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Lead change of a HIF-2α antagonist guided by multiparameter optimization and utilization of an Olp→π*Ar interaction

Paul M. Wehn; Song Yang; Jonas A. Grina; James P. Rizzi; Stephen T. Schlachter; Bin Wang; Rui Xu; Hanbiao Yang; Xinlin Du; Guangzhou Han; Keshi Wang; Robert M. Czerwinski; Emily L. Ged; Heli Huang; Megan M. Halfmann; Melissa A. Maddie; Emily R. Morton; Sarah R. Olive; Huiling Tan; Shanhai Xie; John A. Josey; Eli M. Wallace
Medicinal Chemistry Research · Vol. 32, Issue 7 · pp. 1510-1531 · 2023
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Bibliographic Information

JournalMedicinal Chemistry Research
PublisherSpringer
Publication Date2023-07-01
Publication Year2023
Volume32
Issue7
Pages1510-1531
Document TypeJournal Article
Print ISSN1054-2523
eISSN1554-8120
DOI10.1007/s00044-023-03088-w

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NARA Access Coverage2004-01-01~Current
Journal Homepagehttps://www.springer.com/journal/44
Publisher PageOpen Publisher Page
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