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Journal Article

Optimising Fronto-Orbital Distraction for Management of Unicoronal Craniosynostosis

Yunus Samiepour; Jonas Mellgren; Ce Liang; Philip G. Cox; Hans Delye; Karin Säljö; Lars Kölby; Mehran Moazen
Annals of Biomedical Engineering · 2026

Abstract

Purpose Unicoronal craniosynostosis (UCS) involves premature fusion of the left or right coronal suture, resulting in skull deformities and facial asymmetry. Fronto-orbital distraction (FOD) has proven effective for surgically correcting UCS; however, determining optimal surgical parameters (e.g. distraction angle, length, and distractor number) remains challenging. This study aimed to optimise FOD for UCS using finite element (FE) analysis and simulated surgical outcomes. Methods We developed a patient-specific FE model using pre- and postoperative computed tomography (CT) scans from a 23-day-old UCS patient. The model simulated FOD with varying distraction angles (20°, 30°, 40°), lengths (20–40 mm), and use of single or dual distractors. Thirty-six scenarios were analysed to evaluate impact on skull morphology, orbital symmetry, and facial correction. The model was validated against clinical outcomes using postoperative CT scans. Key metrics included orbital index symmetry and orbital dystopia angle (ODA). Results Distraction length most significantly impacted outcomes, with 40-mm advancement yielding superior orbital symmetry. The optimal configuration (single distractor, 40°, 40-mm advancement) achieved an ODA of 2.2° and orbital index difference (OID) of 0.2%. Dual distractors offered only marginal improvements (ODA: 1.7°; OID: 0.2%) and introduced risks of excessive anterior displacement. Conclusion These findings suggest that optimal FOD outcomes for UCS can be achieved with a single distractor at 40° and 40-mm advancement. Dual distractors provided minimal additional benefit and may increase surgical complexity and risks. The validated FE model offers a quantitative framework for surgical planning and improving the precision of craniosynostosis correction.

Bibliographic Information

JournalAnnals of Biomedical Engineering
PublisherSpringer
Publication Date2026-08-24
Publication Year2026
Document TypeJournal Article
Print ISSN0090-6964
eISSN1573-9686
DOI10.1007/s10439-026-04322-3

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NARA Access Coverage1972-01-01~Current
Journal Homepagehttps://www.springer.com/journal/10439
Publisher PageOpen Publisher Page
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