Abstract
In recent years, the impacts of global warming, including glacial melting, extreme weather events, food crises, and epidemics, have become increasingly severe, posing significant challenges to global sustainability. The primary driver of the current climate crisis is the substantial emission of greenhouse gases (GHGs), particularly carbon dioxide (CO 2 ). Microalgae, as photoautotrophic microorganisms, offer a promising solution by utilizing CO 2 for biosynthesis. Previous research indicates that microalgae can fix CO 2 at rates exceeding 1.5 kg/m 2 /year under optimal conditions, and produce lipids with high content of unsaturated fatty acids. This review delves into recent advancements understanding the causes and effects of global warming, with a particular focus on agricultural GHG emissions. It critically examines the carbon sequestration mechanisms of microalgae and their potential as single-cell biofactories for carbon neutralization and biomanufacturing. The review highlights their ability to fix CO 2 and produce high-value products such as biofuels, chemicals, pharmaceuticals, and foods. Among these species, the characteristics and value of seven edible microalgae are also described. We outline the technical and economic challenges associated with scaling up microalgae cultivation from laboratory to industrial scale, including the optimization of cultivation systems and the improvement of harvesting and processing techniques. This review serves as a useful and informative reference for the application of CO 2 capture and high-value bioproducts by microalgae, aiming to provide a reference for the realization of carbon neutrality and the mitigation of climate change.