Fondaparinux attenuates methotrexate-induced hepatotoxicity by regulating coagulation, endothelial dysfunction, and inflammatory signaling via the TLR4/NLRP3 and NF-κB/IL-1β/MCP-1 pathways

Asmaa Saleh; Nahed A. Raslan; Heba Mohammed Refat M. Selim; Ahmed Mohamed Farghly; Abdel-Gawad S. Shalkami; Mohamed Fathy Mohamed Sallam; Shaza M. Elhusseiny; Saad Ali S. Aljohani; Manar Seleem Fouda; Mohammed Hegazy Hassan Ali; Alaa A. A Abd allatif; Mohamed Fathy AbdElhamid Mohamed; Safaa M. Hanafy; Amany F. Mohamed; Amina Ibrahim Badawy; Somia Mokabel Mohamed; Asmaa Magdy Elashrey; Sara Nagdy Mahmoud Mousa; Ahmed M. El-Dessouki