A High Threshold of Biotherapeutic Aggregate Numbers is Needed to Induce an Immunogenic Response In Vitro, In Vivo, and in the Clinic

Joseph R. Cohen; Stephen R. Brych; Siddharth Prabhu; Vivian Bi; Ahmed Elbaradei; Joshua M. Tokuda; Cathie Xiang; Martha Hokom; Xiaohong Cui; Claudia Ly; Nathan Amos; Jilin Sun; Dominador Calamba; Jonathan Herskovitz; Allyson Capili; Kimya Nourbakhsh; Anthony Merlo; Julia Carreon; Jette Wypych; Linda O. Narhi; Vibha Jawa; Marisa K. Joubert