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Mini-PBPK-Based Population Model and Covariate Analysis to Assess the Complex Pharmacokinetics and Pharmacodynamics of RO7449135, an Anti-KLK5/KLK7 Bispecific Antibody in Cynomolgus Monkeys

Hao Cai; Xun Tao; Jeongsup Shim; Rebecca N. Bauer; Meire Bremer; Wei Bu; Jason LaMar; Rachel Basile; Edward Dere; Tien Nguyen; Steven Laing; Pamela Chan; Tangsheng Yi; James T. Koerber; Gizette Sperinde; Eric Stefanich
The AAPS Journal · Vol. 25, Issue 4 · 2023
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Abstract

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Bibliographic Information

JournalThe AAPS Journal
PublisherSpringer
Publication Date2023-06-23
Publication Year2023
Volume25
Issue4
Document TypeJournal Article
eISSN1550-7416
DOI10.1208/s12248-023-00829-y

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NARA Access Coverage1999-01-01~Current
Journal Homepagehttps://www.springer.com/journal/12248
Publisher PageOpen Publisher Page
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