Engineering a thermostable imine reductase through ancestral sequence reconstruction enables one-pot chemoenzymatic synthesis of (S)-nicotine - Luyun Ji; Guangyao Li; Yuhao Zhuang; Xiaorui Chen; Zhiwei Deng; Changmei Liu; Zhengshan Luo; Yan Zhang; Yijian Rao; Zhenbo Yuan (Food Bioscience, 2026)