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Nitrosamine drug substance-related impurities cause DNA methylation adducts in vitro and in primary hepatocytes upon Cytochrome P450-dependend metabolic activation

Matthias Vogel; Max J. Carlsson; Claudia Skowron; Christina Felske; Rhys Whomsley; Jörg Fahrer
Regulatory Toxicology and Pharmacology · Vol. 167 · pp. 106036 · 2026
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Bibliographic Information

JournalRegulatory Toxicology and Pharmacology
PublisherAcademic Press
Publication Date2026-05-01
Publication Year2026
Volume167
Pages106036
Document TypeJournal Article
eISSN0273-2300
DOI10.1016/j.yrtph.2026.106036
SubjectEnvironmental Science

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NARA Access Coverage1981-06-01~Current
Journal Homepagehttps://www.sciencedirect.com/science/journal/02732300
Publisher PageOpen Publisher Page
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