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The use of total versus unbound exposures for reporting safety margins during drug development: An IQ consortium analysis of pharmaceutical industry practice

Bart A. Jessen; William Angus; Vijay P. Kale; Malar Pannirselvam; Tristan S. Maurer; Shannon Dallas; Nancy Chen
Regulatory Toxicology and Pharmacology · Vol. 170 · pp. 106123 · 2026
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Bibliographic Information

JournalRegulatory Toxicology and Pharmacology
PublisherAcademic Press
Publication Date2026-09-01
Publication Year2026
Volume170
Pages106123
Document TypeJournal Article
eISSN0273-2300
DOI10.1016/j.yrtph.2026.106123
SubjectEnvironmental Science

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NARA Access Coverage1981-06-01~Current
Journal Homepagehttps://www.sciencedirect.com/science/journal/02732300
Publisher PageOpen Publisher Page
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