NARA Discovery
Article Details
← Back to Search Results
Journal Article

Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?

Christian Monsé; Rolf Merget; Jürgen Bünger; Dirk Pallapies; Thomas Brüning
Archives of Toxicology · Vol. 97, Issue 10 · pp. 2813-2818 · 2023

Abstract

Exposure to airborne substances such as gases, vapours, and particles remains a relevant health risk in many workplaces. A current topic and cause for discussion is the investigation of the health effects of particles containing zinc oxide (ZnO). Among other data, those collected from our study on human exposure data of ZnO in 2018 prompted the National Research Centre for the Working Environment 2021 to formulate a new, sharply lowered proposed occupational exposure limit (OEL) for zinc in workplaces. Since the publication of the Danish report, further studies have been conducted with ZnO. In the following text, all arguments for deriving this new limit value for zinc from the report are discussed, extended with the more recent data since 2018. It should be noted that especially the application of time extrapolation factors needs further discussion and harmonization between regulatory authorities. From our point of view, the data situation can justify a higher OEL for zinc than that proposed by the Danish National Research Centre for the Working Environment.

Bibliographic Information

JournalArchives of Toxicology
PublisherSpringer
Publication Date2023-10-01
Publication Year2023
Volume97
Issue10
Pages2813-2818
Document TypeJournal Article
Print ISSN0340-5761
eISSN1432-0738
DOI10.1007/s00204-023-03567-4

Access Information

NARA Access Coverage1930-01-01~Current
Journal Homepagehttps://www.springer.com/journal/204
Publisher PageOpen Publisher Page
Full-text access depends on NARA's subscribed coverage and institutional access.