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Deriving safe limits for N-nitroso-bisoprolol by error-corrected next-generation sequencing (ecNGS) and benchmark dose (BMD) analysis, integrated with QM modeling and CYP-docking analysis

Stephanie Simon; Jörg Schlingemann; George Johnson; Christian Brenneis; Brunhilde Guessregen; Jakub Kostal; Jessica Dieckhoff
Archives of Toxicology · Vol. 99, Issue 10 · pp. 3935-3962 · 2025
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Bibliographic Information

JournalArchives of Toxicology
PublisherSpringer
Publication Date2025-10-01
Publication Year2025
Volume99
Issue10
Pages3935-3962
Document TypeJournal Article
Print ISSN0340-5761
eISSN1432-0738
DOI10.1007/s00204-025-04103-2

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NARA Access Coverage1930-01-01~Current
Journal Homepagehttps://www.springer.com/journal/204
Publisher PageOpen Publisher Page
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