Journal Article
Genetic analysis of human parainfluenza virus type 4 associated with severe acute respiratory infection in children in Luohe City, Henan Province, China, during 2017–2018
Shanshan Zhou; Naiying Mao; Yan Zhang; Aili Cui; Zhen Zhu; Ruiping Hu; Jin Xu; Wenbo Xu
Archives of Virology · Vol. 166, Issue 9 · pp. 2585-2590 · 2021
Abstract
During 2017–2018, nasopharyngeal aspirates (NPAs) from 627 hospitalized patients with severe acute respiratory infection at Luohe Center Hospital were tested by RT-PCR for human parainfluenza virus 4 (HPIV-4). Fourteen (2.2%) of the 627 samples were positive for HPIV-4. The complete HN gene was amplified from nine positive samples and sequenced. Sequence comparisons showed that the HPIV-4 strains circulating in the city of Luohe are closely related to HPIV-4A strains. Our study indicated that there were multiple lineages of HPIV-4 circulating in Henan Province in China during the study period. This will improve our understanding of the epidemiological and clinical characteristics of HPIV-4.
Bibliographic Information
| Journal | Archives of Virology |
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| Publisher | Springer |
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| Publication Date | 2021-09-01 |
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| Publication Year | 2021 |
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| Volume | 166 |
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| Issue | 9 |
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| Pages | 2585-2590 |
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| Document Type | Journal Article |
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| Print ISSN | 0304-8608 |
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| eISSN | 1432-8798 |
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| DOI | 10.1007/s00705-021-05154-3 |
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