Mitochondria are enveloped by an outer membrane (OM) and possess a highly complex inner membrane (IM) with multiple cristae invaginations. We asked how the dynamics of the receptor Tom20 in the OM and ATP synthase in the IM would be affected by the membrane architecture. Single molecule tracking of fluorescence-labeled single particles revealed striking differences in the mobility patterns and diffusion coefficients: ATP synthase is trapped in cristae, while Tom20 is highly diffusive.
| Journal | BIOspektrum |
|---|---|
| Publisher | Springer |
| Publication Date | 2022-10-01 |
| Publication Year | 2022 |
| Volume | 28 |
| Issue | 6 |
| Pages | 586-589 |
| Document Type | Journal Article |
| Print ISSN | 0947-0867 |
| eISSN | 1868-6249 |
| DOI | 10.1007/s12268-022-1830-6 |
| NARA Access Coverage | 2011-01-01~Current |
|---|---|
| Journal Homepage | https://www.springer.com/journal/12268 |
| Publisher Page | Open Publisher Page |