Abstract
The microalgae Dunaliella tertiolecta phototrophically generates glycerol as an osmolyte in response to salt stress. This biogenic carbon sink is also a platform intermediate for the chemical sector. A synergistic genome and time resolved proteome analysis deciphered the metabolic pathways activated under salt stress. Immediately (30 min) Ca 2+ signaling pathways and ions channels are activated, while in the longer term (24 h) cellular energy production and homeostasis pathways are upregulated.