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Journal Article

New progress of tuberculosis scar carcinoma

Wenwen Sun; Yujin Liu; Lishu Zhao; Hao Wang; Li Ye; Xinyue Liu; Kandi Xu; Yu Chen; Lin Fan
Cancer and Metastasis Reviews · Vol. 42, Issue 3 · pp. 653-659 · 2023

Abstract

It has been demonstrated that scar tissue and fibrosis may increase the likelihood of developing malignancies. Specifically, scar tissue has been linked to the occurrence and progression of lung cancer (LC), though the precise mechanisms necessitate further research for explanation. Lung scarring can stem from various causes, with carcinogenesis on scarring lesions in pulmonary tuberculosis (PTB) being the most frequent (accounting for approximately 75% of cases). Notably, having previously cured, PTB is the second most common risk factor for LC after smoking, with approximately 3% of PTB patients experiencing LC as a secondary condition. This essay will delve into the mechanisms, treatment, and prognosis of tuberculosis scar carcinoma (TSC).

Bibliographic Information

JournalCancer and Metastasis Reviews
PublisherSpringer
Publication Date2023-09-01
Publication Year2023
Volume42
Issue3
Pages653-659
Document TypeJournal Article
eISSN1573-7233
DOI10.1007/s10555-023-10128-9

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NARA Access Coverage1982-01-01~Current
Journal Homepagehttps://www.springer.com/journal/10555
Publisher PageOpen Publisher Page
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