Journal Article
Induction of spermiation in common carp after enhanced intestinal uptake of sGnRH‐A and Pimozide
I. Roelants; T. Mikolajczyk; P. Epler; F. Ollevier; J. Chyb; B. Breton
Journal of Fish Biology · Vol. 56, Issue 6 · pp. 1398-1407 · 2000
Abstract
The inherent ability of the carp Cyprinus carpio gut to absorb intact salmon gonadotropin hormone‐releasing hormone analogue (sGnRH‐a)+Pimozide (Pim), without loss of their bioactivity is very limited. Artificial intestinal absorption enhancement boosted sGnRH‐a and Pim induced GtH II release and milt production significantly. The intraperitoneal route of administration was more effective than the oral one. A potential application of the oral route for peptidergic drug delivery and the possibility of developing a dietary delivery system is discussed.
Bibliographic Information
| Journal | Journal of Fish Biology |
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| Publisher | Wiley |
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| Publication Date | 2000-06-01 |
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| Publication Year | 2000 |
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| Volume | 56 |
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| Issue | 6 |
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| Pages | 1398-1407 |
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| Document Type | Journal Article |
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| Print ISSN | 0022-1112 |
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| eISSN | 1095-8649 |
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| DOI | 10.1111/j.1095-8649.2000.tb02152.x |
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| Subject | General Aquaculture, Fisheries & Fish Science |
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