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Journal Article

Systems of conductive skin for power transfer in clinical applications

Andreas P. Kourouklis; Julius Kaemmel; Xi Wu; Evgenij Potapov; Nikola Cesarovic; Aldo Ferrari; Christoph Starck; Volkmar Falk; Edoardo Mazza
European Biophysics Journal · Vol. 51, Issue 2 · pp. 171-184 · 2022

Abstract

The primary aim of this article is to review the clinical challenges related to the supply of power in implanted left ventricular assist devices (LVADs) by means of transcutaneous drivelines. In effect of that, we present the preventive measures and post-operative protocols that are regularly employed to address the leading problem of driveline infections. Due to the lack of reliable wireless solutions for power transfer in LVADs, the development of new driveline configurations remains at the forefront of different strategies that aim to power LVADs in a less destructive manner. To this end, skin damage and breach formation around transcutaneous LVAD drivelines represent key challenges before improving the current standard of care. For this reason, we assess recent strategies on the surface functionalization of LVAD drivelines, which aim to limit the incidence of driveline infection by directing the responses of the skin tissue. Moreover, we propose a class of power transfer systems that could leverage the ability of skin tissue to effectively heal short diameter wounds. In this direction, we employed a novel method to generate thin conductive wires of controllable surface topography with the potential to minimize skin disruption and eliminate the problem of driveline infections. Our initial results suggest the viability of the small diameter wires for the investigation of new power transfer systems for LVADs. Overall, this review uniquely compiles a diverse number of topics with the aim to instigate new research ventures on the design of power transfer systems for IMDs, and specifically LVADs.

Bibliographic Information

JournalEuropean Biophysics Journal
PublisherSpringer
Publication Date2022-03-01
Publication Year2022
Volume51
Issue2
Pages171-184
Document TypeJournal Article
Print ISSN0175-7571
eISSN1432-1017
DOI10.1007/s00249-021-01568-8

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NARA Access Coverage1974-01-01~Current
Journal Homepagehttps://www.springer.com/journal/249
Publisher PageOpen Publisher Page
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