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Effects of cytochrome P450 (CYP3A4 and CYP2C19) inhibition and induction on the exposure of selumetinib, a MEK1/2 inhibitor, in healthy subjects: results from two clinical trials

Angela W. Dymond; Karen So; Paul Martin; Yifan Huang; Paul Severin; David Mathews; Eleanor Lisbon; Gabriella Mariani
European Journal of Clinical Pharmacology · Vol. 73, Issue 2 · pp. 175-184 · 2017
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Bibliographic Information

JournalEuropean Journal of Clinical Pharmacology
PublisherSpringer
Publication Date2017-02-01
Publication Year2017
Volume73
Issue2
Pages175-184
Document TypeJournal Article
Print ISSN0031-6970
eISSN1432-1041
DOI10.1007/s00228-016-2153-7

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NARA Access Coverage1968-01-01~Current
Journal Homepagehttps://www.springer.com/journal/228
Publisher PageOpen Publisher Page
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