Journal Article
Letermovir for the compassionate therapeutic use of cytomegalovirus infection
Lorenz Schubert; Lisa Fisecker; Florian Thalhammer; Heinz Burgmann; Christoph Steininger
European Journal of Clinical Microbiology & Infectious Diseases · Vol. 40, Issue 2 · pp. 435-439 · 2021
Abstract
Purpose Data on the efficacy, dosing and safety of letermovir for the compassionate therapeutic use of CMV infections are limited. Methods Clinical and virological efficacy of letermovir was assessed in a retrospective single-centre study of patients who received letermovir for the compassionate therapeutic use of CMV infections. Results Letermovir initiation yielded prompt treatment response in 7 out of 9 patients (77.7%). Conclusion Letermovir may be an effective and well tolerated option in the compassionate treatment of CMV infections, although recurrence of CMV and emergence of resistance may be issues.
Bibliographic Information
| Journal | European Journal of Clinical Microbiology & Infectious Diseases |
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| Publisher | Springer |
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| Publication Date | 2021-02-01 |
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| Publication Year | 2021 |
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| Volume | 40 |
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| Issue | 2 |
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| Pages | 435-439 |
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| Document Type | Journal Article |
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| Print ISSN | 0934-9723 |
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| eISSN | 1435-4373 |
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| DOI | 10.1007/s10096-020-03990-w |
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