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Journal Article

Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever

Sheila B. Buijs; Sanne K. Stuart; Jan Jelrik Oosterheert; Steffi Karhof; Andy I. M. Hoepelman; Nicole H. M. Renders; André S. van Petersen; Chantal P. Bleeker-Rovers; Peter C. Wever; Olivier H. J. Koning
European Journal of Clinical Microbiology & Infectious Diseases · Vol. 40, Issue 7 · pp. 1569-1572 · 2021

Abstract

We evaluated the long-term serological follow-up of patients with vascular risk factors for chronic Q fever that were previously C oxiella burnetii seropositive. C. burnetii phase I IgG titers were reevaluated in patients that gave informed consent or retrospectively collected in patients already deceased or lost to follow-up. Of 107 patients, 25 (23.4%) became seronegative, 77 (72.0%) retained a profile of past resolved Q fever infection, and five (4.7%) developed chronic Q fever. We urge clinicians to stay vigilant for chronic Q fever beyond two years after primary infection and perform serological testing based on clinical presentation.

Bibliographic Information

JournalEuropean Journal of Clinical Microbiology & Infectious Diseases
PublisherSpringer
Publication Date2021-07-01
Publication Year2021
Volume40
Issue7
Pages1569-1572
Document TypeJournal Article
Print ISSN0934-9723
eISSN1435-4373
DOI10.1007/s10096-021-04179-5

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NARA Access Coverage1982-01-01~Current
Journal Homepagehttps://www.springer.com/journal/10096
Publisher PageOpen Publisher Page
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