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A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response

Tyler A. U. Hilsabeck; Ru Liu-Bryan; Tracy Guo; Kenneth A. Wilson; Neelanjan Bose; Daniel Raftery; Jennifer N. Beck; Sven Lang; Kelly Jin; Christopher S. Nelson; Tal Oron; Marshall Stoller; Daniel Promislow; Rachel B. Brem; Robert Terkeltaub; Pankaj Kapahi
GeroScience · Vol. 44, Issue 4 · pp. 2195-2211 · 2022

Abstract

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Bibliographic Information

JournalGeroScience
PublisherSpringer
Publication Date2022-08-01
Publication Year2022
Volume44
Issue4
Pages2195-2211
Document TypeJournal Article
eISSN2509-2723
DOI10.1007/s11357-022-00557-9

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NARA Access Coverage1978-01-01~Current
Journal Homepagehttps://www.springer.com/journal/11357
Publisher PageOpen Publisher Page
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