Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project

Amanda E. Coleman; Kate E. Creevy; Rozalyn Anderson; May J. Reed; Virginia R. Fajt; Kathleen M. Aicher; Genna Atiee; Brian G. Barnett; Ryan D. Baumwart; Beth Boudreau; Suzanne M. Cunningham; Matthew D. Dunbar; Bobbie Ditzler; Anna M. Ferguson; Kiersten K. Forsyth; Anya N. Gambino; Sonya G. Gordon; Hillary K. Hammond; Sydney N. Holland; Mary K. Iannaccone; Kate Illing; Saki Kadotani; Shelby A. Knowles; Evan L. MacLean; Brian A. Maran; Lauren E. Markovic; Stephanie McGrath; Rachel L. Melvin; Mikaela S. Mueller; O. Lynne Nelson; Natasha J. Olby; Theresa E. Pancotto; Elizabeth Parsley; Brianna M. Potter; Jena O. Prescott; Ashley B. Saunders; Holly M. Sawyer; Brian A. Scansen; Sarah M. Schmid; Courtney C. Smith; Sonja S. Tjostheim; M. Katherine Tolbert; Melissa A. Tropf; Lance C. Visser; Jessica L. Ward; Sonya R. Wesselowski; Rebecca C. Windsor; Vicky K. Yang; Audrey Ruple; Daniel E. L. Promislow; Matt Kaeberlein; Joshua M. Akey; Brooke Benton; Elhanan Borenstein; Marta G. Castelhano; Amanda E. Coleman; Kate E. Creevy; Annette L. Fitzpatrick; Kyle Crowder; Matthew D. Dunbar; Virginia R. Fajt; Annette L. Fitzpatrick; Unity Jeffery; Erica C. Jonlin; Matt Kaeberlein; Elinor K. Karlsson; Kathleen F. Kerr; Jonathan M. Levine; Jing Ma; Robyn L. McClelland; Daniel E. L. Promislow; Audrey Ruple; Stephen M. Schwartz; Sandi Shrager; Noah M. Snyder-Mackler; M. Katherine Tolbert; Silvan R. Urfer; Benjamin S. Wilfond