Second-tier trio exome sequencing after negative solo clinical exome sequencing: an efficient strategy to increase diagnostic yield and decipher molecular bases in undiagnosed developmental disorders

Frederic Tran Mau-Them; Sebastien Moutton; Caroline Racine; Antonio Vitobello; Ange-Line Bruel; Sophie Nambot; Steven A. Kushner; Femke M. S. de Vrij; Daphné Lehalle; Nolwenn Jean-Marçais; François Lecoquierre; Julian Delanne; Julien Thevenon; Charlotte Poe; Thibaut Jouan; Martin Chevarin; David Geneviève; Marjolaine Willems; Christine Coubes; Nada Houcinat; Alice Masurel-Paulet; Anne-Laure Mosca-Boidron; Emilie Tisserant; Patrick Callier; Arthur Sorlin; Yannis Duffourd; Laurence Faivre; Christophe Philippe; Christel Thauvin-Robinet