Selective phosphodiesterase 4 inhibitor roflumilast reduces inflammation and lung injury in models of betacoronavirus infection in mice

Vinícius Amorim Beltrami; Flávia Rayssa Braga Martins; Débora Gonzaga Martins; Celso Martins Queiroz-Junior; Franciel Batista Félix; Letícia Cassiano Resende; Felipe Rocha da Silva Santos; Larisse de Souza Barbosa Lacerda; Victor Rodrigues de Melo Costa; Walison Nunes da Silva; Pedro Pires Goulart Guimaraes; Goulart Guimaraes; Frederico Marianetti Soriani; Mauro Martins Teixeira; Vivian Vasconcelos Costa; Vanessa Pinho