Short-term ambient particulate matter pollution of different sizes and respiratory hospital admission in the Beibu Gulf area of Southern China - Haopeng Li; Lizhong Liang; Shiyu Zhang; Zhengmin (Min) Qian; Miao Cai; Xiaojie Wang; Stephen Edward McMillin; Amy E. Keith; Jing Wei; Yan Geng; Hualiang Lin (Atmospheric Environment, 2023)

Bixasteroid, a new compound from the fruits of Bixa orellana and its anti-inflammatory activity - Yi-min Chen; Tian-qi Xu; Xiao-qi Zhang; Chun-lin Fan; Wen-cai Ye; Wei Xu; Guang-xiong Zhou (Natural Product Research, 2023)

Intercropping with maize (Zea mays L.) enhanced the suppression of pepper (Capsicum annuum L.) Phytophthora blight by arbuscular mycorrhizal fungi - Junli Hu; Shaowei Hou; Peng Cai; Minghui Li; Zhang Cheng; Fuyong Wu; Xiangui Lin (Journal of Soils and Sediments, 2023)

Inhibitory Effects of Bacillus Coagulans TL3 on the Ileal Oxidative Stress and Inflammation Induced by Lipopolysaccharide in Rats - Jia Chen; Jing Cai; Jiaxi Lin; Ziyang Cheng; Miao Long (Current Microbiology, 2023)

Association of Dietary and Plasma Magnesium with Glycaemic Markers in a Chinese Population - Min Xu; Jiansheng Cai; Xiaoting Mo; Qiumei Liu; Junling Zhang; Yanfei Wei; Shuzhen Liu; Yinxia Lin; Shenxiang Huang; Chunbao Mo; Tingyu Mai; Dechan Tan; et al. (Biological Trace Element Research, 2023)

Spatiotemporal Characteristics and Future Scenario Simulation of the Trade-offs and Synergies of Mountain Ecosystem Services: A Case Study of the Dabie Mountains Area, China - Lin Fang; Yanxiao Liu; Canfeng Li; Jun Cai (Chinese Geographical Science, 2023)

Phosphorus availability mediates plant–plant interaction and field productivity in maize-grass pea intercropping system: Field experiment and its global validation - Shuang-Guo Zhu; Hong-Yan Tao; Wen-Bo Li; Rui Zhou; Yan-Wen Gui; Li Zhu; Xiao-Lin Zhang; Wei Wang; Bao-Zhong Wang; Fu-Jian Mei; Hao Zhu; You-Cai Xiong (Agricultural Systems, 2023)

Immune‐enhancing effects of Astragalus polysaccharides and Ganoderma lucidum polysaccharides on Vibrio harveyi flgJ DNA vaccine in grouper - Guixiang Lin; Fan Da; Xiaoju Wan; Yucong Huang; Shiping Yang; Jichang Jian; Shuanghu Cai (Journal of Fish Diseases, 2023)
Astragalus polysaccharides (APS) and Ganoderma lucidum polysaccharides (GLP) have been shown to possess strong immunoregulatory properties in aquatic animals. In this study, the fragment containing Vibrio harveyi flgJ gene was ligated into pcDNA3.1(+) vector and pcDNA3.1(+)‐flgJ was constructed as DNA vaccine. APS and GLP were used as DNA vaccine adjuvants to evaluate the immunoregulatory effect by intramuscular injection to pearl gentian grouper ( ♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus ). The results showed that pcDNA3.1(+)‐flgJ combined with APS or GLP could significantly up‐regulate the innate and adaptive immune response in fish, including serum‐specific antibody titres, catalase and lysozyme activities. At the same time, DNA vaccine combined with APS or GLP significantly up‐regulated the expression levels of CD8α , IgM , IL‐1β , MHC‐Iα , MyD88 and TLR3 genes in thymus, head kidney, spleen and liver of pearl gentian grouper in comparison with those of the pFlgJ group. After 42 days post‐vaccination, V. harveyi was used to challenge pearl gentian grouper by intraperitoneal injection. The relative percentage of survival (RPS) of pFlgJ, pFlgJ +APS, pFlgJ +GLP and pFlgJ+APS+GLP groups were 69%, 81%, 77% and 88%, respectively. These results suggested APS and GLP were potential adjuvants for DNA vaccine against V. harveyi infection in pearl gentian grouper.

Temperature-dependent effects of neonicotinoids on the embryonic development of zebrafish (Danio rerio) - Yolina Yu Lin Wang; Yan-Er Cai; Syed Shabi Ul Hassan Kazmi; Jing Yang; Yuwen Wang; Ping Li; Wenhua Liu; Zhen Wang (Frontiers in Marine Science, 2023)
The agricultural use of neonicotinoids is increasing worldwide and poses a threat to non-target organisms. The existing toxicity data of neonicotinoids that is mainly focused on widely used neonicotinoids ignores the influence of environmental factors, like temperature, related to climate changes, etc . To fill this data gap, the present study assessed the temperature-dependent toxicity of six neonicotinoids at four temperatures. Briefly, a fish embryo toxicity test was performed at the following temperatures—20, 23, 28, and 33°C—on zebrafish embryos to evaluate the lethal and sublethal effects of these toxicants. At 28°C, the lethal toxicity (LC 50 ) values for these toxicants were cycloxaprid—3.36 mg/L, nitenpyram—7.08 mg/L, paichongding—17.2 mg/L, imidaclothiz—738.6 mg/L, dinotefuran—2,096 mg/L, and thiamethoxam—4,293 mg/L, respectively. Among the sublethal effects, the enzymatic activities changed significantly in neonicotinoid treatments, which revealed oxidative stress, metabolic disorders, and neurotoxicity. Particularly, acetylcholinesterase inhibition and glutathione S-transferase activation showed a significant dose–response relationship. However, cycloxaprid, nitenpyram, and paichongding were found to be more potent compared with imidaclothiz and thiamethoxam. The influence of temperature on these neonicotinoids demonstrated an inverted V-shaped relationship, in which toxicity decreased with the increase of temperature and then increased with the increase of temperature after exceeding the optimum temperature. This study provides a reference for the multiscale effects and potential mechanisms of neonicotinoids. Temperature-dependent toxicity is of great significance for future toxicity testing and risk assessment of chemicals in the face of global climate changes.

Revealing microcystin-LR ecotoxicity to earthworm (Eisenia fetida) at the intestinal cell level - Xiang Liu; Jin-Cheng Ye; Fen Li; Rong-Jun Gao; Xiao-Xiao Wang; Ji-Liang Cheng; Bai-Lin Liu; Lei Xiang; Yan-Wen Li; Quan-Ying Cai; Hai-Ming Zhao; Ce-Hui Mo; et al. (Chemosphere, 2023)

Ambient air pollution, bone mineral density and osteoporosis: Results from a national population-based cohort study - Yin Yang; Rui Li; Miao Cai; Xiaojie Wang; Haopeng Li; Yinglin Wu; Lan Chen; Hongtao Zou; Zilong Zhang; Haitao Li; Hualiang Lin (Chemosphere, 2023)

Using habitat classification and large-scale spatial planning model to identify environmental areas: A case study in the area of the Northwest Pacific Ocean - Huang Hao; Cai Lei; Lei Wang; Weiwen Li; Ou Danyun; Wu Lijun; Ou Rimei; Lin Lianghua (Marine Policy, 2023)

VUV/UV oxidation performance for the elimination of recalcitrant aldehydes in water and its variation along the light-path - Wan-Yue Ouyang; Wen-Long Wang; Yi-Lin Zhang; Han-Ying Cai; Qian-Yuan Wu (Water Research, 2023)

Ambient particulate matter pollution of different sizes associated with recurrent stroke hospitalization in China: A cohort study of 1.07 million stroke patients - Miao Cai; Xiaojun Lin; Xiaojie Wang; Shiyu Zhang; Zhengmin (Min) Qian; Stephen Edward McMillin; Hannah E. Aaron; Hualiang Lin; Jing Wei; Zilong Zhang; Jay Pan (Science of The Total Environment, 2023)

Banana MaERF124 negatively modulates carotenoid accumulation during fruit ripening through repression of carotenogenesis genes - Danling Cai; Hong Xu; Zongli Liu; Nanhui Chen; Lisha Zhu; Zengxiang Lin; Chaojie Wu; Wei Shan; Jianye Chen; Wangjin Lu; Lin Chen; Jianfei Kuang (Postharvest Biology and Technology, 2023)

Estimating small structural motions from multi-view video measurement - Enjian Cai; Yi Zhang; Xiaodong Ji; Xinzheng Lu; Linlin Xie; Yuncheng Zhuang; Taisen Zhao; Guangwei Lin (Engineering Structures, 2023)

Dual-activation interfacial polymerization based anionic covalent organic framework nanofiltration membrane for high-flux dye separation - Yixin Yang; Guorong Li; Dan Ouyang; Zongwei Cai; Zian Lin (Chemical Engineering Journal, 2023)

Cation-doped V2O5 microsphere as a bidirectional catalyst to activate sulfur redox reactions for lithium-sulfur batteries - Fan-Jun Liu; Wen-Lin Luo; Ze Zhang; Ji Yu; Jian-Xin Cai; Zhen-Yu Yang (Chemical Engineering Journal, 2023)

Constructing efficient CuO -CeO2 catalyst for NO reduction by CO: New insights into the structure–activity relationship - Wei Tan; Yandi Cai; Shaohua Xie; Juntian Xu; Kaili Ma; Kailong Ye; Lu Ma; Steven N. Ehrlich; Weixin Zou; Fei Gao; Lin Dong; Fudong Liu (Chemical Engineering Journal, 2023)

Developing membrane reactors with suspended polyphthalocyanine nanoplatelets for upscaling syntheses of protein-polymer bioconjugates - Wen Fang Wei; Wan Lin Guo; Min Jian; Liu Shu Qin; Xue Li; Tao Cai (Chemical Engineering Journal, 2023)

Dual-targeting celecoxib nanoparticles protect intestinal epithelium and regulate macrophage polarization for ulcerative colitis treatment - Ruijie Chen; Xinlu Lin; Qian Wang; Xingsi An; Xinyu Zhao; Yujie Lin; Tuyue Sun; Chenyang Yan; Aimin Cai; Weilan Cao; Youting Zhang; Qing Yao; et al. (Chemical Engineering Journal, 2023)

Corrigendum to “Novel diketopyrrolopyrrole NIR-II fluorophores and DDR inhibitors for in vivo Chemo-photodynamic therapy of Osteosarcoma” [Chem. Eng. J. 446 (2022) 136929] - Xiaoding Cheng; Chong Zhang; Kun Shen; Huifan Liu; Caihong Bai; Qihang Ding; Mengting Guan; Junzhu Wu; Zhiquan Tian; Deliang Chen; Lin Cai; Xuechuan Hong; et al. (Chemical Engineering Journal, 2023)

K+ and CeO2 nanoparticles modified OMS-2 nanorods for enhanced activity and stability of photocatalytic toluene oxidation: K+ charge modulation and mechanistic investigation - Pingping Yu; Nan Li; Weixin Zou; Xiaoqian Wei; Jiawei Ji; Li Han; Yandi Cai; Wei Tan; Bin Gao; Lin Dong (Chemical Engineering Journal, 2023)

In-situ growth of bimetallic FeCo-MOF on magnetic biochar for enhanced clearance of tetracycline and fruit preservation - Yi-Cai Jiang; Meng-Fan Luo; Zi-Nuo Niu; Si-Yuan Xu; Yue Gao; Yuan Gao; Wen-Juan Gao; Jing-Jing Luo; Rui-Lin Liu (Chemical Engineering Journal, 2023)

Lightweight Flexible Polyimide-Derived Laser-Induced Graphenes for High-Performance Thermal Management Applications - Yu-Sheng Hsiao; Cai-Wan Chang-Jian; Tzu-Yen Huang; Ying-Lin Chen; Chung-Wei Huang; Jen-Hsien Huang; Nian-Jheng Wu; Shih-Chieh Hsu; Chih-Ping Chen (Chemical Engineering Journal, 2023)

Filling the gap between molecular and aggregate states: how does molecular packing affect photophysical properties? - Xu-Min Cai; Yuting Lin; Zhenguo Tang; Xuedan Zhang; Tianqi Mu; Shenlin Huang; Zheng Zhao; Ben Zhong Tang (Chemical Engineering Journal, 2023)

Ammonia fiber expansion-assisted deep eutectic solvent treatment for wheat straw fraction separation and bioconversion - Mingyang Hu; Lin Yuan; Ziyuan Cai; Weihua Zhang; Qiang Fu; Dandan Ji (Bioresource Technology, 2023)

SATB1/SLC7A11/HO-1 Axis Ameliorates Ferroptosis in Neuron Cells After Ischemic Stroke by Danhong Injection - Sikai Zhan; Jiayin Liang; Huiting Lin; Jiale Cai; Xinxin Yang; Hongwei Wu; Junying Wei; Shumei Wang; Minghua Xian (Molecular Neurobiology, 2023)

A microfluidic immunosensor based on magnetic separation for rapid detection of okadaic acid in marine shellfish - Yuxiang Ji; Gaozhe Cai; Cheng Liang; Zehang Gao; Weimin Lin; Zizhen Ming; Shilun Feng; Hongwei Zhao (Analytica Chimica Acta, 2023)

The emergence of prolonged deadly humid heatwaves - Xiang‐Sheng Wang; Lei He; Xiao‐Hu Ma; Qiang Bie; Lin Luo; You‐Cai Xiong; Jian‐Sheng Ye (International Journal of Climatology, 2022)
Deadly humid heat conditions exceeding human thermoregulatory capacity have been reported; however, whether and where the deadly humid heat events occur consecutively across the land surface are largely unknown. We calculate the maximum consecutive days of deadly humid heat, defined as daily maximum wet‐bulb temperature (TWmax) ≥35°C, for observations of 9,278 meteorological stations and for simulations of 14 global climate models. We further define short and long deadly humid heatwaves as a period of 3–4 and ≥5 consecutive days with daily TWmax ≥35°C, respectively. Our analyses show that six stations in some subtropical regions have experienced deadly humid heat with daily TWmax ≥35°C, but only occurs in individual days. Deadly humid heatwaves increase exponentially as the global mean temperature rising. When limiting global warming within 1.5°C, long deadly humid heatwaves will not occur across the land surface, and short deadly humid heatwaves will only emerge in some drylands but not in humid areas. Under 2°C warming, 0.09% of the global land, 0.42% of the human population, and 0.56% of the global centres of crop diversity are projected to be exposed to long deadly humid heatwaves. Meanwhile, 18% of the deadly humid heatwaves lasting ≥3 consecutive days will occur in humid areas; the fractions are projected to rapidly increase in humid areas as temperature rising further. At the end of the century, the percentage of land areas and human population exposed to deadly humid heatwaves lasting ≥3 consecutive days are expected to be 76‐times higher than that under 1.5°C warming level. Our finding suggests that keeping global warming within 1.5°C will significantly constrain the emergence of prolonged deadly humid heatwaves and thus reduce the risk of the human population especially outdoor agricultural workers.

Cloning, characterization and expression analysis of caspase-8 genes from the golden pompano (Trachinotus ovatus) - Fan Da; Xiaoju Wan; Guixiang Lin; Jichang Jian; Shuanghu Cai (Frontiers in Marine Science, 2022)
Bacterial infection triggers apoptosis and immunity by regulating the expression of caspases. In this article, we report two caspase-8 paralogs, termed ToCas8 and ToCas8 -like, from an economically important teleost golden pompano ( Trachinotus ovatus ). Caspase-8 is a classic cysteine protease that is essential for the initiation and execution of apoptosis and is a critical regulator in initiating death receptor-induced programmed cell death. The two proteins encoded by ToCas8 and ToCas8 -like were characterized by multiple sequence alignment and protein structure analysis showing similarity to their counterparts in vertebrates and exhibiting typical features of the Caspase-8 protein family. Gene synteny analysis further confirmed that two isoforms of caspase-8 genes exactly existed in golden pompano. Phylogenetic analysis showed that the Caspase-8 proteins of the selected species in the study were clustered together, and Cas8 and Cas8-like were clustered into two different subgroups. In addition, ToCas8 and ToCas8 -like were widely distributed and both were expressed at high levels in gill, kidney and intestinal tissues. Transcript levels of ToCas8 and ToCas8 -like were significantly upregulated in response to LPS and Poly(I:C) challenges, suggesting that caspase-8 genes are involved in the immune response to pathogens. In summary, we have identified two isoforms of caspase-8 in golden pompano that are involved in the immune response. These findings will expand our understanding of the evolutionary history and functional characteristics of caspase-8 genes in vertebrates.

Isolation and evaluation of strong endogenous promoters for the heterologous expression of proteins in Pichia pastoris - Yafei Zhang; Shengyan Wang; Lingfang Lu; Chenshan Zhang; Fan Cai; Yao Lin; Yide Huang (World Journal of Microbiology and Biotechnology, 2022)

Rapid Determination in the Quality Control of Chinese Patent Medicine - Shao Hua Lu; Ming Cai Zhang; Hong Lin Zhai; Ke Xin Bi; Bing Qiang Zhao (Journal of Pharmaceutical Innovation, 2022)

Locus-level antagonistic selection shaped the polygenic architecture of human complex diseases - Weichen Song; Kai Yuan; Zhe Liu; Wenxiang Cai; Jue Chen; Shunying Yu; Min Zhao; Guan Ning Lin (Human Genetics, 2022)

An association study on the risk, glucocorticoids effectiveness, and prognosis of systemic lupus erythematosus: insight from mitochondrial DNA copy number - Zhen Li; Qi-Qun Zong; Chun-Xia Zhai; Guang-Hui Yu; Wan-Qin Hu; Yu-Hua Wang; Lin-Lin Wang; Zi-Ye Yan; Ting-Yu Zhang; Ying Teng; Shuang Liu; Jing Cai; et al. (Immunologic Research, 2022)

Mechanism of simultaneous lead and chromium removal from contaminated wastewater by a schwertmannite-like mineral - Mingyan Shi; Yali Zhang; Weibin Hong; Jiayu Liu; Huijie Zhu; Xu Liu; Yuxin Geng; Zhenyin Cai; Shaonan Lin; Chengzhi Ni (Environmental Science and Pollution Research, 2022)

A comprehensive review on water stable metal-organic frameworks for large-scale preparation and applications in water quality management based on surveys made since 2015 - R. Y. Li; Z. S. Wang; Z. Y. Yuan; Constance Van Horne; Viatcheslav Freger; M. Lin; R. K. Cai; J. P. Chen (Critical Reviews in Environmental Science and Technology, 2022)

Design of deep-sea chemical data collector for the seafloor observatory network - Bin Lv; Jie Chen; Hai-lin Liu; Chao Liu; Zhao-wen Zhang; Xiao-nan Zhang; Hao Gao; Yu-long Cai (Marine Georesources & Geotechnology, 2022)

Synthesis and biological evaluation of new thiazolyl-urea derivatives as potential dual C-RAF/FLT3 inhibitors - Zhi-Hua Zhang; Bi-Fan Zeng; Zhe-Xue Song; Ying-Yu Yang; Kai-yun Zhang; Xue Du; Lin-lin Zhang; Dong Cai (Medicinal Chemistry Research, 2022)

Prediction of black carbon in marine engines and correlation analysis of model characteristics based on multiple machine learning algorithms - Ying Sun; Lin Lü; Yun-kai Cai; Peng Lee (Environmental Science and Pollution Research, 2022)

Genome sequence of the novel freshwater Microcystis cyanophage Mwe-Yong1112-1 - Ruqian Cai; Dengfeng Li; Wei Lin; Weinan Qin; Lingting Pan; Fei Wang; Minhua Qian; Wencai Liu; Qin Zhou; Chengxu Zhou; Yigang Tong (Archives of Virology, 2022)

The particle fluxes in sediment traps from Niulang Guyot area in the Northwest Pacific Ocean - Xiuwu Sun; Jinmin Chen; Baohong Chen; Cai Lin; Yang Liu; Jiang Huang; Zhong Pan; Kaiwen Zhou; Qing He; Fangfang Kuang; Hui Lin (Acta Oceanologica Sinica, 2022)

Nutrient distributions and nitrogen-anomaly (N*) in the tropical North Pacific Ocean - Aiqin Han; Yu Wang; Yunlong Huo; Cai Lin; Kaiwen Zhou; Fangfang Kuang; Hui Lin (Acta Oceanologica Sinica, 2022)

Baseline establishment for metals in the western Clarion-Clipperton Zone - Cai Lin; Yang Liu; Ronggen Jiang; Jinmin Chen; Baohong Chen; Weili Wang; Kaiwen Zhou; Hui Lin (Acta Oceanologica Sinica, 2022)

Identification of serum metabolites enhancing inflammatory responses in COVID-19 - Chen-Song Zhang; Bingchang Zhang; Mengqi Li; Xiaoyan Wei; Kai Gong; Zhiyong Li; Xiangyang Yao; Jianfeng Wu; Cixiong Zhang; Mingxia Zhu; Lei Zhang; Xiufeng Sun; et al. (Science China Life Sciences, 2022)

Positive predictive value of noninvasive prenatal testing for sex chromosome abnormalities - Nan Guo; Meiying Cai; Min Lin; Huili Xue; Hailong Huang; Liangpu Xu (Molecular Biology Reports, 2022)
Background Early and intermediate serological screening cannot detect sex chromosome abnormalities. Currently, noninvasive prenatal testing (NIPT) is the only procedure available for screening such disorders; however, its use is controversial. Methods and Results A total of 47,855 pregnant women underwent NIPT at our referral center from January 2014 to December 2020. Of the 314 patients with a positive NIPT indicating sex chromosome abnormalities, 260 were screened via karyotype analysis and single nucleotide polymorphism (SNP) array after amniotic fluid extraction; 96 cases were confirmed. Karyotype analysis and SNP array were consistent in the diagnosis of 88 out of the 96 fetuses. The positive predictive value (PPV) for sex chromosome abnormalities was found to be 36.9%. The PPV in patients aged 30–34 years was significantly higher than that in patients aged < 30 years. No statistically significant difference was observed on the PPV among patients with or without previous adverse pregnancy outcomes. Moreover, 83 women carrying fetuses were diagnosed with a sex chromosome abnormality terminated their pregnancy. Conclusions Improvements in detection and analytical technologies are needed to increase the accuracy of sex chromosome abnormalities detection. Pregnant women with a positive NIPT for these abnormalities may require invasive diagnostic procedures such as karyotype analysis and SNP array for better genetic counseling.

Identification of a 5-gene-risk score model for predicting luminal A-invasive lobular breast cancer survival - Yi-Huan Chen; Tao-Feng Zhang; Yi-Yuan Liu; Jie-Hua Zheng; Wei-Xun Lin; Yao-Kun Chen; Jie-Hui Cai; Juan Zou; Zhi-Yang Li (Genetica, 2022)

Variations of suspended sediment transport caused by changes in shoreline and bathymetry in the Zhujiang (Pearl) River Estuary in the wet season - Shicheng Lin; Jianwei Niu; Guangping Liu; Xing Wei; Shuqun Cai (Acta Oceanologica Sinica, 2022)

Microbial transformation of distinct exogenous substrates into analogous composition of recalcitrant dissolved organic matter - Jie Lian; Xiaoxuan Zheng; Xiaocun Zhuo; Yi‐Lung Chen; Chen He; Qiang Zheng; Ta‐Hui Lin; Jia Sun; Weidong Guo; Quan Shi; Nianzhi Jiao; Ruanhong Cai (Environmental Microbiology, 2022)

Potential and Distribution of Natural Gas Hydrate Resources in the South China Sea - Pibo Su; Lin Lin; Yaoyao Lv; Jinqiang Liang; Yunbao Sun; Wei Zhang; Huice He; Baiquan Yan; Zhanhuai Ji; Lifeng Wang; Feifei Wang; Mengya Cai (Journal of Marine Science and Engineering, 2022)
The amount of natural gas contained in the world’s gas hydrate accumulations is enormous, but these estimates remain highly speculative. So far, it is still challenging to locate spatial distribution of marine gas hydrate and quantitatively characterize the evaluation parameters and systematic improvement of evaluation systems. Considering the systematic review of the key accumulation factors, such as heat flow, deposition rate and total organic carbon in the typical passive continental margin, the evaluation results of global marine gas hydrate resources were analyzed based on the characteristics of gas hydrate geology, geophysics and geochemistry anomalies in the South China Sea. We analyze the problems on the evaluation of marine gas hydrate resources, probing into the geological characteristics and distribution laws of marine gas hydrate resources in the South China Sea, and estimate the parameters for in-place resource evaluation, in which the volume method based on Monte Carlo probability was used to evaluate the gas hydrate potential resources in the South China Sea. The probability distribution ranges from 37.6 billion (with 90% probability) to 117.7 billion (with 10% probability) tons of oil equivalent, with an expected value of 74.4 billion tons of oil equivalent. The study results show that the gas hydrate resource density in the South China Sea is similar to that in the typical sea areas, and the estimated global resources are basically consistent with the assessment results at this stag; this shows that the South China Sea has great potential for gas hydrate resources. The research results can provide guidance for the evaluation of global climate change and the exploration and development of hydrate resources.

Boundary Layer Features of One Winter Fog in the Yangtze River Delta, China - Peifeng Shen; Duanyang Liu; Ismail Gultep; Huijuan Lin; Ninghao Cai; Shuya Cao; Zida Wang (Pure and Applied Geophysics, 2022)

Two new clerodane diterpenoids and a new pyran-2-one derivative with anti-neuroinflammatory activities from Croton crassifolius - Zhi-Peng Ling; Qing Tang; Can-Jie Li; Jin-Lin Tan; Hai-Yue Zhao; Yi-Kun Hao; Zhao-Chun Zhan; Zhong-Nan Wu; Yu-Bo Zhang; Qing Zheng; Guo-Cai Wang (Journal of Natural Medicines, 2022)

Identification and QTL mapping of important agronomic traits based on rice short-wide grain CSSL-Z752 with restorer line Xihui 18 as background - Lin-Jun Cai; Han Yun; Xiao-Long Zhong; Dan Du; Xi-Man Peng; Ji-Chao Dai; Zhen-Lin Yang; Fang-Ming Zhao; Chang-Wei Zhang (Cereal Research Communications, 2022)

Ancylostoma ceylanicum Infection in a Miniature Schnauzer Dog Breed - Xu-Hui Lin; Hai-Ming Cai; Zhuan-Qiang Yan; Shen-Quan Liao; Min-Na Lv; Cai-Yan Wu; Juan Li; Jun-Jing Hu; Wen-Wan Xiao; Jian-Fei Zhang; Nan-Shan Qi; Ming-Fei Sun (Acta Parasitologica, 2022)

Identification and molecular mapping of YrBm for adult plan resistance to stripe rust in Chinese wheat landrace Baimangmai - Chaoyue Hu; Fengtao Wang; Jing Feng; Cai Sun; Jiyuan Guo; Xiaowei Lang; Jinghuang Hu; Bin Bai; Wentao Zhang; Hongjie Li; Ruiming Lin; Shichang Xu (Theoretical and Applied Genetics, 2022)

Characteristics and comparative analysis of Mesona chinensis Benth chloroplast genome reveals DNA barcode regions for species identification - Danfeng Tang; Yang Lin; Fan Wei; Changqian Quan; Kunhua Wei; Yanyan Wei; Zhongquan Cai; Muhammad Haneef Kashif; Jianhua Miao (Functional & Integrative Genomics, 2022)

Effects of different carbon sources and carbon–nitrogen ratios on the survival, growth, intestinal biochemical parameters, and water quality of seahorse juveniles cultured under zero-water exchange conditions - Tingting Lin; Yishan Cai; Xin Liu; Siping Li; Dong Zhang; Lianjun Xia (Aquaculture International, 2022)

High animal protein diet and gut microbiota in human health - Jie Cai; Zhongxu Chen; Wei Wu; Qinlu Lin; Ying Liang (Critical Reviews in Food Science and Nutrition, 2022)

Three new sesquiterpene lactones from the whole plants of Elephantopus scaber - Ding-Chai Lin; Qing Tang; Xue-Fang Zhuo; Wen-Zhi Wang; Can-Jie Li; Guang-Kai Kuang; Zhong-Nan Wu; Yu-Bo Zhang; Guo-Cai Wang; Yao-Lan Li (Natural Product Research, 2022)

Efficient de novo assembly and modification of large DNA fragments - Shuangying Jiang; Yuanwei Tang; Liang Xiang; Xinlu Zhu; Zelin Cai; Ling Li; Yingxi Chen; Peishuang Chen; Yuge Feng; Xin Lin; Guoqiang Li; Jafar Sharif; et al. (Science China Life Sciences, 2022)

Green supply chain game model and contract design: risk neutrality vs. risk aversion - Jianhu Cai; Huazhen Lin; Xiaoqing Hu; Minyan Ping (Environmental Science and Pollution Research, 2022)

Derivation of water quality criteria for glyphosate and its formulations to protect aquatic life in China - Yili Fan; Kaibo Zhang; Ruiqing Zhang; Guanghui Guo; Huixian Li; Yingchen Bai; Ying Lin; Ting Cai (Environmental Science and Pollution Research, 2022)

Associations Between Plasma Metals and Cognitive Function in People Aged 60 and Above - Junling Zhang; Qiumei Liu; Min Xu; Jiansheng Cai; Yanfei Wei; Yinxia Lin; Xiaoting Mo; Shenxiang Huang; Shuzhen Liu; Chunbao Mo; Tingyu Mai; Dechan Tan; et al. (Biological Trace Element Research, 2022)

Enhanced Extracellular Matrix Degradation in Growth Plate Contributes to Manganese Deficiency-Induced Tibial Dyschondroplasia in Broiler Chicks - Peng-Fei Dong; Cong Jin; Cai-Yu Lian; Lin Wang; Zhen-Yong Wang (Biological Trace Element Research, 2022)

Biochemical and structural characterization of the cyanophage‐encoded phosphate‐binding protein: implications for enhanced phosphate uptake of infected cyanobacteria - Fangxin Zhao; Xingqin Lin; Kun Cai; YongLiang Jiang; Tianchi Ni; Yue Chen; Jianrong Feng; Shangyu Dang; Cong‐Zhao Zhou; Qinglu Zeng (Environmental Microbiology, 2022)
Summary To acquire phosphorus, cyanobacteria use the typical bacterial ABC‐type phosphate transporter, which is composed of a periplasmic high‐affinity phosphate‐binding protein PstS and a channel formed by two transmembrane proteins PstC and PstA. A putative pstS gene was identified in the genomes of cyanophages that infect the unicellular marine cyanobacteria Prochlorococcus and Synechococcus . However, it has not been determined whether the cyanophage PstS protein is functional during infection to enhance the phosphate uptake rate of host cells. Here we showed that the cyanophage P‐SSM2 PstS protein was abundant in the infected Prochlorococcus NATL2A cells and the host phosphate uptake rate was enhanced after infection. This is consistent with our biochemical and structural analyses showing that the phage PstS protein is indeed a high‐affinity phosphate‐binding protein. We further modelled the complex structure of phage PstS with host PstCA and revealed three putative interfaces that may facilitate the formation of a chimeric ABC transporter. Our results provide insights into the molecular mechanism by which cyanophages enhance the phosphate uptake rate of cyanobacteria. Phosphate acquisition by infected bacteria can increase the phosphorus contents of released cellular debris and virus particles, which together constitute a significant proportion of the marine dissolved organic phosphorus pool.

Biflavonoids from the twigs and leaves of Cephalotaxus oliveri Mast. and their α -glucosidase inhibitory activity - Min Song; Tong Xiao; Qiu-Shuang Wu; Hang Fai Kwok; Ging Chan; Li-Gen Lin; Xiao-Qi Zhang; Wen-Cai Ye; Sheng-Jiang He; Qing-Wen Zhang (Natural Product Research, 2022)

Ergosterol peroxide: an effect-directed detecting method from Anoectochilus elwesii and evaluation of anticancer activity - Yanduan Lin; Bingqin Wen; Ziwei Zhang; Jinyan Cai (Natural Product Research, 2022)

Near-Optimal Control for Offshore Structures with Nonlinear Energy Sink Mechanisms - Wei Chen; Xingyu Du; Bao-Lin Zhang; Zhihui Cai; Zhongqiang Zheng (Journal of Marine Science and Engineering, 2022)
To improve the safety and reliability of offshore structures subject to wave loading, the active vibration control problem is always one of significant issues in the field of ocean engineering. This paper deals with the near–optimal control problem of offshore structures with a nonlinear energy sink (NES) mechanism. By taking the dominant vibration mode of the offshore structure with the NES into account, a nonlinear dynamic model of the steel–jacket structure subject to wave loading is presented first. Then, using the parameter perturbation approach to solve a nonlinear two–point boundary value problem, an NES–based optimal controller with the form of infinite series sum is presented to suppress the vibration of the offshore structure. Third, an iteration algorithm is provided to obtain the near–optimal controller. Simulation results demonstrate that the NES–based near–optimal controller can mitigate the oscillation amplitude of offshore structures significantly. Moreover, the NES–based optimal controller outperforms the one based on active tuned mass damper.

Sandstorms cause shrinkage of Haloxylon ammodendron shrubs and limit their self-renewal - Sheng-bo Shi; Dang-wei Zhou; Fang-lin Wang; Rui Shi; Tao Sun; Tian-cai Li; Jia-lin Ma; Xiang Wan; Jian-ping Ma; Jing-nian Tang (Theoretical and Experimental Plant Physiology, 2022)
Haloxylon ammodendron is an excellent windproof and sand-fixing species whose shrubs are widely cultivated in arid desert areas of northwest China but are now at risk of degradation and shrinkage. Using the chlorophyll fluorescence image analysis technique, the response of photosystem II (PSII) photochemical efficiency and non-photochemical quenching capacity to sediment-carrying wind and sand-free wind (both 12 m s −1 ) lasting for 10, 20, and 40 min were studied with seedlings in a wind tunnel. The results indicated that the sand-free wind had little influence on the maximum quantum efficiency of PSII photochemistry, F v / F m , which was approximately 0.80 on average; however, the F v / F m decreased over exposure time in the sediment-carrying wind group, with values smaller than those in the wind-only group. The non-photochemical quenching was sensitive to wind erosion, and sediment-carrying wind could aggravate the reduction in non-photochemical quenching ( NPQ ). Except for the 10 min duration, the maximum quantum efficiency of PSII photochemistry after dark recovery for 15 min, F v r / F m r , was lower in seedlings exposed to sediment-carrying wind than in those in the wind-only group. Compared to wind-only, wind-blown sand led to a water imbalance and withering in seedlings, causing the concentration of photosynthetic pigments (when based on the fresh mass of green branches) to not decrease. With a longer exposure time to sediment-carrying wind, both the probability and extent of lignified spots occurring increased in green assimilative branches. Our results demonstrated that sediment-carrying wind at 12 m s −1 lasting for 20 min or more could cause irreversible damage to the photosynthetic apparatus of H. ammodendron seedlings. Therefore, frequent and strong sandstorms are the main disturbance factors leading to shrinkage of shrubs and limiting their self-renewal.

Phosphorus fertilization affects soybean rhizosphere phosphorus dynamics and the bacterial community in karst soils - Jihui Tian; Xing Lu; Qianqian Chen; Xizhi Kuang; Cuiyue Liang; Lansheng Deng; Dongjiao Lin; Kunzheng Cai; Jiang Tian (Plant and Soil, 2022)

Moss biocrusts buffer the negative effects of karst rocky desertification on soil properties and soil microbial richness - Cai Cheng; Yujie Li; Mingzhong Long; Min Gao; Yuandong Zhang; Jiayu Lin; Xiaona Li (Plant and Soil, 2022)

Molecular cloning, characterization and expression analysis of two 12-oxophytodienoate reductases (NtOPR1 and NtOPR2) from Nicotiana tabacum - Feiyan Huang; Farhat Abbas; Dylan O’Neill Rothenberg; Muhammad Imran; Sajid Fiaz; Naveed ur Rehman; Sikandar Amanullah; Afifa Younas; Yan Ding; Xianjie Cai; Xiaolong Chen; Lei Yu; et al. (Molecular Biology Reports, 2022)

miR-21-5p serves as a promoter in renal cell carcinoma progression through ARHGAP24 downregulation - Bin Meng; Pengfei Wang; Chaofei Zhao; Guangwei Yin; Xin Meng; Lin Li; Shengyong Cai; Chengquan Yan (Environmental Science and Pollution Research, 2022)

Comparison of the Macrozoobenthic Community and Sedimentary Environment with and Without Horseshoe Crab Presence in the Crocodile Island Intertidal Zone, Xiamen, China - Lizhe Cai; Xiaoyu Zhao; Wenqing Peng; Jingxiang Lin; Deyuan Yang; Yiyong Rao; Sujing Fu; Xinwei Chen; Wenzhi Cao (Journal of Ocean University of China, 2022)

Secoiridoid glycosides from the fruits of Cornus officinalis - Xin Wang; Xiang-Jian Zhong; Na Zhou; Lin-Lin Ji; Jin-Jie Li; Ning Cai; Qing-Bo Wang; Peng-Cheng Lin; Xiao-Ya Shang (Natural Product Research, 2022)

Global burden of chronic obstructive pulmonary disease attributable to ambient particulate matter pollution and household air pollution from solid fuels from 1990 to 2019 - Yinglin Wu; Shiyu Zhang; Bingting Zhuo; Miao Cai; Zhengmin Min Qian; Michael G. Vaughn; Stephen Edward McMillin; Zilong Zhang; Hualiang Lin (Environmental Science and Pollution Research, 2022)

Baculoviruses hijack the visual perception of their caterpillar hosts to induce climbing behaviour thus promoting virus dispersal - Xiaoming Liu; Zhiqiang Tian; Limei Cai; Zhongjian Shen; J. P. Michaud; Lin Zhu; Shuo Yan; Vera I. D. Ros; Kelli Hoover; Zhen Li; Songdou Zhang; Xiaoxia Liu (Molecular Ecology, 2022)
Baculoviruses can induce climbing behaviour in their caterpillar hosts to ensure they die at elevated positions to enhance virus transmission, providing an excellent model to study parasitic manipulation of host behaviour. Here, we demonstrate that climbing behaviour occurred mostly during daylight hours, and that the height at death of Helicoverpa armigera single nucleopolyhedrovirus (HearNPV)‐infected larvae increases with the height of the light source. Phototaxic and electroretinogram (ERG) responses were enhanced after HearNPV‐infection in host larvae, and ablation of stemmata in infected larvae prevented both phototaxis and climbing behaviour. Through transcriptome and quantitative PCR, we confirmed that two opsin genes (a blue light‐sensitive gene, HaBL ; and a long wave‐sensitive gene, HaLW ) as well as the TRPL (transient receptor potential‐like channel protein) gene, all integral to the host's visual perception pathway, were significantly upregulated after HearNPV infection. Knockout of HaBL , HaLW , or TRPL genes using the CRISPR/Cas9 system resulted in significantly reduced ERG responses, phototaxis, and climbing behaviour in HearNPV‐infected larvae. These results reveal that HearNPV alters the expression of specific genes to hijack host visual perception at fundamental levels—photoreception and phototransduction—in order to induce climbing behaviour in host larvae.

The RNA-binding protein SND1 promotes the degradation of GPX4 by destabilizing the HSPA5 mRNA and suppressing HSPA5 expression, promoting ferroptosis in osteoarthritis chondrocytes - Min Lv; Yuanzhen Cai; Weikun Hou; Kan Peng; Ke Xu; Chao Lu; Wenxing Yu; Weisong Zhang; Lin Liu (Inflammation Research, 2022)

Lipoxin A4 regulates M1/M2 macrophage polarization via FPR2–IRF pathway - Jixiang Yuan; Feihong Lin; Lichen Chen; Weikang Chen; Xiaodong Pan; Yongheng Bai; Yong Cai; Hong Lu (Inflammopharmacology, 2022)

Characterization of a Diguanylate Cyclase VAGM001033 of Vibrio alginolyticus and Protective Efficacy as a Live Attenuated Vaccine Candidate in Pearl Gentian Grouper - Huiming Tan; Fan Da; Guixiang Lin; Xiaoju Wan; Jichang Jian; Shuanghu Cai (Frontiers in Marine Science, 2022)
Vibrio alginolyticus ( V. alginolyticus ) is one of the important epizootic pathogens in marine animals. VAGM001033 belongs to a diguanylate cyclase, responsible for the synthesis of dimeric guanosine monophosphate (c-di-GMP), a ubiquitous second messenger involved in the function of biofilm formation, motility, and virulence. This study confirmed that VAGM001033 was an active diguanylate cyclase by Congo red assay. The red-stained, dry, and rough form of colonies were observed with the increasing concentration of the L-arabinose on Congo red plates. Also, an in-frame deleted Δ VAGM001033 mutant was constructed and changes of Δ VAGM001033 mutant in physiology and pathogenicity were detected. The Δ VAGM001033 mutant displayed similar morphology and growth curve with the wild-type strain showing no significant differences. The swarming ability of the Δ VAGM001033 mutant was significantly enhanced showing bigger swarming circles, while the biofilm formation, extracellular proteases, and virulence were significantly attenuated. The results of the test for antibiotic susceptibility showed that the wild type and Δ VAGM001033 mutant had similar sensitivity or resistance to most antibiotics used in this study, except cefotaxime and nitrofurantoin. The mutant was sensitive to cefotaxime and nitrofurantoin, while the wild type was intermediate. A total of 756 differentially expressed genes (DEGs) were identified by RNA-seq, of which 109 were upregulated and 647 were downregulated. Flagellar assembly, two-component system, ATP-binding cassette (ABC) transporters, and peptidoglycan biosynthesis were significantly enriched in the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway. Moreover, the Δ VAGM001033 mutant induced high antibody titers and provided immune protectivity with a relative percent survival (RPS) of 82%. Immune-related genes of pearl gentian grouper ( ♀Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus ), namely, IgM , MHC-I α, interleukin-1β ( IL-1 β), interleukin-16 ( IL-16 ), and tumor necrosis factor-α ( TNF- α) were upregulated after vaccination. Overall, the results suggested that VAGM001033 plays a crucial role in V. alginolyticus . The Δ VAGM001033 mutant might be applied as an effective live vaccine candidate against V. alginolyticus .

MoOpy2 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae - Ying‐Ying Cai; Jing‐Yi Wang; Xi‐Yu Wu; Shuang Liang; Xue‐Ming Zhu; Lin Li; Jian‐Ping Lu; Xiao‐Hong Liu; Fu‐Cheng Lin (Environmental Microbiology, 2022)
Summary The development and pathogenicity of the fungus Magnaporthe oryzae , the causal agent of destructive rice blast disease, require it to perceive external environmental signals. Opy2, an overproduction‐induced pheromone‐resistant protein 2, is a crucial protein for sensing external signals in Saccharomyces cerevisiae . However, the biological functions of the homologue of Opy2 in M. oryzae are unclear. In this study, we identified that MoOPY2 is involved in fungal development, pathogenicity, and autophagy in M. oryzae . Deletion of MoOPY2 resulted in pleiotropic defects in hyphal growth, conidiation, germ tube extension, appressorium formation, appressorium turgor generation, and invasive growth, therefore leading to attenuated pathogenicity. Furthermore, MoOpy2 participates in the Osm1 MAPK pathway and the Mps1 MAPK pathway by interacting with the adaptor protein Mst50. The interaction sites of Mst50 and MoOpy2 colocalized with the autophagic marker protein MoAtg8 in the preautophagosomal structure sites (PAS). Notably, the Δ Moopy2 mutant caused cumulative MoAtg8 lipidation and rapid GFP‐MoAtg8 degradation in response to nitrogen starvation, showing that MoOpy2 is involved in the negative regulation of autophagy activity. Taken together, our study revealed that MoOpy2 of M. oryzae plays an essential role in the orchestration of fungal development, appressorium penetration, autophagy and pathogenesis.

The interplay between respectfulness and lexical-semantic in reading Chinese: evidence from ERPs - Liyan Ji; Lin Cai (Cognitive Neurodynamics, 2022)

3D geomechanics modeling of Indonesia B oilfield and its application in wellbore stability - Wenjun Cai; Jingen Deng; Yongcun Feng; Hai Lin; Yanguang Yuan; Dongdong Liu (Arabian Journal of Geosciences, 2022)

Pre- and postharvest measures used to control decay and mycotoxigenic fungi in potato ( Solanum tuberosum L.) during storage - Jia Liu; Zhiqiang Sun; Yuping Zou; Wenhua Li; Fangyun He; Xiaoya Huang; Chenglin Lin; Qingnian Cai; Michael Wisniewski; Xuehong Wu (Critical Reviews in Food Science and Nutrition, 2022)

Isolation and structural elucidation of a low-molecular-weight polysaccharide from the roots of Panax ginseng C. A. Meyer - Bin Zhao; Xin-Ying Wang; Wen Luo; Yue Lin; Chong-Ning Lv; Jin-Cai Lu (Natural Product Research, 2022)

Highly selective monoclonal antibody-based lateral flow immunoassay for visual and sensitive determination of conazole fungicides propiconazole in vegetables - Ze-Ke Xu; Jing-Nan Meng; Yi Lei; Xing-Xing Yang; Yi-Yong Yan; Hai-Hong Liu; Hong-Tao Lei; Ting-Cai Wang; Xing Shen; Zhen-Lin Xu (Food Additives & Contaminants: Part A, 2022)

Technical methodologies for the assessment of the impacts of reclamation projects on marine ecology - Yurong Ouyang; Lin Wu; Juanjuan Dai; Yaojian Wu; Ling Cai; Qingsheng Li; Jianwei Wu; Shang Jiang (Environmental Science and Pollution Research, 2022)

Distribution and source determination of rare earth elements in sediment collected from the continental shelf off Hainan Island, China - Pengjie Cai; Guanqiang Cai; Xuejie Li; Xin Chen; Jie Lin; Shun Li; Zhao Li (Environmental Science and Pollution Research, 2022)

Multi-loop pipe freezing optimization of deep shaft considering seepage effect - Haibing Cai; Fangxing Yao; Rongbao Hong; Jian Lin; Kun Zeng (Arabian Journal of Geosciences, 2022)

Temporal and spatial distribution characteristics of nutrients in Clarion-Clipperton Fracture Zone in the Pacific in 2017 - Baohong Chen; Kaiwen Zhou; Kang Wang; Jigang Wang; Sumin Wang; Xiuwu Sun; Jinmin Chen; Cai Lin; Hui Lin (Acta Oceanologica Sinica, 2022)

210Pb-Derived Bioturbation Rates in Sediments Around Seamounts in the Tropical Northwest Pacific - Feng Lin; Cai Lin; Hui Lin; Xiuwu Sun; Li Lin (Frontiers in Marine Science, 2021)
To evaluate bioturbation coefficients (D B ) and mixing depths (L), 210 Pb and 226 Ra activity was measured in two sediments cores (from water depths of 5,398 m and 4,428 m), which were collected from seamount areas in the Northwest Pacific. Using a steady-state diffusion mode, we estimated D B values of 16.8 and 24.1 cm 2 /a, higher than those in abyssal sediments and those predicted by traditional empirical equations. Corresponding L values varied between 19.3 and 23.1 cm. These high values indicate that seamounts are the area of active bioturbation. A one-dimensional model for the transport of total organic carbon (TOC) from the surface layer of sediments to the deep layer was developed using the distribution pattern of the specific activity of excess 210 Pb ( 210 Pb ex ) and its relationship with TOC. The model showed that the TOC flux transmitted downward by bioturbation was 0.09 mmol/(cm 2 ⋅a) and 0.12 mmol/(cm 2 ⋅a).

Human Bone Marrow Mesenchymal Stem Cell–Derived Exosomes Attenuate Blood–Spinal Cord Barrier Disruption via the TIMP2/MMP Pathway After Acute Spinal Cord Injury - Wang Xin; Shi Qiang; Ding Jianing; Liang Jiaming; Lin Fangqi; Cai Bin; Chen Yuanyuan; Zhang Guowang; Xu Jianguang; Lian Xiaofeng (Molecular Neurobiology, 2021)

Expression profiling of WRKY transcription factors in Spinach - Yaying Ma; Shuai Chen; Hongying Yu; Ruoyu Li; Zhicong Lin; Mingxing Cai; Min Tang; Xingtan Zhang; Ray Ming (Euphytica, 2021)

Applicability evaluation and improvement of different snow evaporation calculation methods in the Great Xing’an mountains - Youwei Lin; Tijiu Cai; Cunyong Ju; Xueqing Cui (Earth Science Informatics, 2021)

MiR-34b-3p Impaired HUVECs Viability and Migration via Targeting PDK1 in an In Vitro Model of Gestational Diabetes Mellitus - Feiluan Song; Anli Cai; Qianwen Ye; Xiang Chen; Lin Lin; Xi Hao (Biochemical Genetics, 2021)

Three new ester glycosides with cytotoxic activity from the seeds of Caesalpinia sappan - Min Wang; Juan Tan; Jun Chen; Tian Xie; Liang-Mo Lin; Li-Li Zhong; Xing-Jun Cai; Qiong-Shi Wu (Natural Product Research, 2021)

Dopaminergic Projection from Ventral Tegmental Area to Substantia Nigra Pars Reticulata Mediates Chronic Social Defeat Stress–Induced Hypolocomotion - Feng He; Pei Zhang; Qian Zhang; Guangjian Qi; Hongwei Cai; Tongxia Li; Ming Li; Jiazhen Lu; Jiaen Lin; Jie Ming; Bo Tian (Molecular Neurobiology, 2021)

Evaluation of the antifungal activity of Lysurus mokusin extract against Pestalotiopsis neglecta and GC–MS analysis of the active components - Lian-Nan Lin; Jing Yang; Guo-Cai Zhang; Xiao-Bo Zhang; Ting-Yu Wang; De-Dong Wu (Journal of Plant Pathology, 2021)

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Late Cretaceous adakitic rocks from the western Tibetan Plateau: implications for the subduction of the Neo-Tethys Ocean - Wei Wang; Qing-Guo Zhai; Pei-Yuan Hu; Sun-Lin Chung; Yue Tang; Hai-Tao Wang; Zhi-Cai Zhu; Hao Wu; Zhi-Qiang Huang (International Geology Review, 2021)

Alfalfa (Medicago sativa L.) MsCML46 gene encoding calmodulin-like protein confers tolerance to abiotic stress in tobacco - Binghao Du; Naiyu Chen; Lili Song; Dan Wang; Hongsheng Cai; Lin Yao; Xiuting Li; Changhong Guo (Plant Cell Reports, 2021)

Production of purple Ma bamboo (Dendrocalamus latiflorus Munro) with enhanced drought and cold stress tolerance by engineering anthocyanin biosynthesis - Mengqi Xiang; WenSha Ding; Chu Wu; Wenjia Wang; Shanwen Ye; Changyang Cai; Xin Hu; Nannan Wang; Weiyuan Bai; Xiaoshan Tang; Caiping Zhu; Xiaomin Yu; et al. (Planta, 2021)

Evaluating a Modified High Purity Polysorbate 20 Designed to Reduce the Risk of Free Fatty Acid Particle Formation - Nidhi Doshi; Kyle Ritchie; Tamanna Shobha; Jamie Giddings; Kathrin Gregoritza; Rosalynn Taing; Stephen Rumbelow; Jeff Chu; Anthony Tomlinson; Aadithya Kannan; Miguel Saggu; Si Kai Cai; et al. (Pharmaceutical Research, 2021)

Magnetic Resonance Imaging-Guided and Navigated Individualized Repetitive Transcranial Magnetic Stimulation for Cognitive Impairment in Schizophrenia - Xu-Sha Wu; Tian-Cai Yan; Xian-Yang Wang; Yang Cao; Xiao-Fan Liu; Yu-Fei Fu; Lin Wu; Yin-Chuan Jin; Hong Yin; Long-Biao Cui (Neuroscience Bulletin, 2021)

Effect of Quicklime on Microbial Community in Strong Acidic Soil - Junwei Liang; Xiangquan Yu; Yafan Cao; Jiguang Zhang; Ning Yan; Lin Xue; Xianjie Cai; Guoming Shen (Journal of Soil Science and Plant Nutrition, 2021)

The relationship between anthocyanin accumulation and photoprotection in young leaves of two dominant tree species in subtropical forests in different seasons - Zheng-Chao Yu; Wei Lin; Xiao-Ting Zheng; Wah Soon Chow; Yan-Na Luo; Min-Ling Cai; Chang-Lian Peng (Photosynthesis Research, 2021)

The major photoprotective role of anthocyanins in leaves of Arabidopsis thaliana under long-term high light treatment: antioxidant or light attenuator? - Xiao-Ting Zheng; Zheng-Chao Yu; Jun-Wei Tang; Min-Ling Cai; Yi-Lin Chen; Cheng-Wei Yang; Wah Soon Chow; Chang-Lian Peng (Photosynthesis Research, 2021)

Photosynthetic compensation of non-leaf organ stems of the invasive species Sphagneticola trilobata (L.) Pruski at low temperature - Min-ling Cai; Wen-qiao Ding; Jun-jie Zhai; Xiao-ting Zheng; Zheng-chao Yu; Qi-lei Zhang; Xiao-hua Lin; Wah Soon Chow; Chang-lian Peng (Photosynthesis Research, 2021)

Genipin Attenuates Tau Phosphorylation and Aβ Levels in Cellular Models of Alzheimer’s Disease - Meiting Li; Nan Cai; Liang Gu; Lijun Yao; Decheng Bi; Weishan Fang; Zhijian Lin; Yan Wu; Hong Xu; Hui Li; Zhangli Hu; Xu Xu (Molecular Neurobiology, 2021)

Dynamic changes in size‐fractionated dissolved organic matter composition in a seasonally ice‐covered Arctic River - Hui Lin; Huacheng Xu; Yihua Cai; Claude Belzile; Robie W. Macdonald; Laodong Guo (Limnology and Oceanography, 2021)
Arctic rivers are sensitive to climate and environmental change, but the biogeochemical response remains poorly understood. Monthly size‐fractionated dissolved organic matter (DOM) samples from the lower Yukon River were characterized using UV–visible, fluorescence, and Fourier transform‐infrared (FT‐IR) spectroscopy techniques. The EEM‐PARAFAC analysis revealed three major fluorescent DOM components, including two humic‐like components (C 480 and C 400 ) and one protein‐like component (C 310 ), with their relative importance following the order of C 480 ≥ C 400 > C 310 in the high‐molecular‐weight DOM (1 kDa–0.4 μ m) and C 400 > C 480 > C 310 in the low‐molecular‐weight DOM pool ( S 275–295 ) and specific UV absorbance at 254 nm (SUVA 254 ). These changes occurred within different DOM size‐fractions and among ice‐covered, spring freshet, and open seasons. Joint analysis of EEM and FT‐IR spectra using a data fusion technique showed that humic‐like DOM is mostly associated with C─H, C═C, and C─O bonds, while protein‐like DOM is correlated more with C─N and N─H related structures. DOM aromaticity and the ratios of HIX to BIX and protein‐like to humic‐like components may be used as a compelling proxy to measure change in source waters and to infer permafrost dynamics. Our results provide insight into the seasonal variation in DOM composition for different size‐fractions in the lower Yukon River, and a baseline dataset against which future changes can be understood in the context of arctic basin biogeochemical cycling.

The developmental regulator PatD modulates assembly of the cell‐division protein FtsZ in the cyanobacterium Anabaena sp. PCC 7120 - Li Wang; Tian‐Cai Niu; Ana Valladares; Gui‐Ming Lin; Ju‐Yuan Zhang; Antonia Herrero; Wen‐Li Chen; Cheng‐Cai Zhang (Environmental Microbiology, 2021)
Summary FtsZ is a tubulin‐like GTPase that polymerizes to initiate the process of cell division in bacteria. Heterocysts are terminally differentiated cells of filamentous cyanobacteria that have lost the capacity for cell division and in which the ftsZ gene is downregulated. However, mechanisms of FtsZ regulation during heterocyst differentiation have been scarcely investigated. The patD gene is NtcA dependent and involved in the optimization of heterocyst frequency in Anabaena sp. PCC 7120. Here, we report that the inactivation of patD caused the formation of multiple FtsZ‐rings in vegetative cells, cell enlargement, and the retention of peptidoglycan synthesis activity in heterocysts, whereas its ectopic expression resulted in aberrant FtsZ polymerization and cell division. PatD interacted with FtsZ, increased FtsZ precipitation in sedimentation assays, and promoted the formation of thick straight FtsZ bundles that differ from the toroidal aggregates formed by FtsZ alone. These results suggest that in the differentiating heterocysts, PatD interferes with the assembly of FtsZ. We propose that in Anabaena FtsZ is a bifunctional protein involved in both vegetative cell division and regulation of heterocyst differentiation. In the differentiating cells PatD‐FtsZ interactions appear to set an FtsZ activity that is insufficient for cell division but optimal to foster differentiation.

Numerical Investigation on Hydrodynamic Performance of a Portable AUV - Lin Hong; Renjie Fang; Xiaotian Cai; Xin Wang (Journal of Marine Science and Engineering, 2021)
This paper conducts a numerical investigation on the hydrodynamic performance of a portable autonomous underwater vehicle (AUV). The portable AUV is designed to cruise and perform some tasks autonomously in the underwater world. However, its dynamic performance is strongly affected by hydrodynamic effects. Therefore, it is crucial to investigate the hydrodynamic performance of the portable AUV for its accurate dynamic modeling and control. In this work, based on the designed portable AUV, a comprehensive hydrodynamic performance investigation was conducted by adopting the computational fluid dynamics (CFD) method. Firstly, the mechanical structure of the portable AUV was briefly introduced, and the dynamic model of the AUV, including the hydrodynamic term, was established. Then, the unknown hydrodynamic coefficients in the dynamic model were estimated through the towing experiment and the plane-motion-mechanism (PMM) experiment simulation. In addition, considering that the portable AUV was affected by wave forces when cruising near the water surface, the influence of surface waves on the hydrodynamic performance of the AUV under different wave conditions and submerged depths was analyzed. Finally, the effectiveness of our method was verified by experiments on the standard models, and a physical experiment platform was built in this work to facilitate hydrodynamic performance investigations of some portable small-size AUVs.

Mid-Level Riverine Outflow Matters: A Case of Microplastic Transport in the Jiulong River, China - Yifan Li; Siguang Liu; Mengyang Liu; Wei Huang; Kai Chen; Yongcheng Ding; Fangzhu Wu; Hongwei Ke; Linghao Lou; Yan Lin; Mingyu Zhang; Fengjiao Liu; et al. (Frontiers in Marine Science, 2021)
Riverine outflow is one of the major pathways for microplastic transportation to coastal environments. Research on the output of microplastics in small- or medium-sized rivers will help accurately understand the status of their marine loads. In this study, we used both trawling and pumping methods to collect microplastics of different sizes in the Jiulong River Estuary and Xiamen Bay. We found that the abundance of small microplastics (44 μm–5.0 mm) was at least 20 times higher than the large particles (0.33–5.0 mm). The abundance of the large particles ranges from 4.96 to 16.3 particles/m 3 , and that of the small particles ranged from 82.8 to 918 particles/m 3 . Granule was the dominant shape (>60%), and polyethylene (PE), polypropylene (PP), and polyethylene terephthalate (PET) were the most common components. The riverine flux of small microplastics (44 μm–5 mm, 472 ± 230 t/y) was at a medium level and was eight times greater than that of large particles (0.33–5.0 mm, 61.2 ± 2.6 t/y). The behavior of the large microplastics was relatively conservative, whose abundance had a significant correlation with salinity ( R 2 = 0.927) and was mainly influenced by physical factors. In contrast, results of statistical analysis revealed that more complicated factors influenced the small microplastics.

Dissociable plasticity of visual-motor system in functional specialization and flexibility in expert table tennis players - Dazhi Yin; Xuefei Wang; Xiaoyou Zhang; Qiurong Yu; Yu Wei; Qing Cai; Mingxia Fan; Lin Li (Brain Structure and Function, 2021)

Activation of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) with Lidocaine Provokes Pyroptosis of Glioblastoma Cells - B. Zhou; Y. Lin; S. Chen; J. Cai; Z. Luo; S. Yu; J. Lu (Bulletin of Experimental Biology and Medicine, 2021)

Five matrine-type alkaloids from Sophora tonkinensis - Qing Tang; Ding Luo; Ding-Chai Lin; Wen-Zhi Wang; Can-Jie Li; Xue-Fang Zhuo; Zhong-Nan Wu; Yu-Bo Zhang; Guo-Cai Wang; Yao-Lan Li (Journal of Natural Medicines, 2021)

Luteolin alleviates ulcerative colitis through SHP-1/STAT3 pathway - Bo-Lin Li; Dan-Yang Zhao; Peng-Li Du; Xiao-Tian Wang; Qian Yang; Yan-Ru Cai (Inflammation Research, 2021)

Microbial transformation of distinct exogenous substrates into analogous composition of recalcitrant dissolved organic matter - Jie Lian; Xiaoxuan Zheng; Xiaocun Zhuo; Yi‐Lung Chen; Chen He; Qiang Zheng; Ta‐Hui Lin; Jia Sun; Weidong Guo; Quan Shi; Nianzhi Jiao; Ruanhong Cai (Environmental Microbiology, 2021)
Summary Oceanic dissolved organic matter (DOM) comprises a complex molecular mixture which is typically refractory and homogenous in the deep layers of the ocean. Though the refractory nature of deep‐sea DOM is increasingly attributed to microbial metabolism, it remains unexplored whether ubiquitous microbial metabolism of distinct carbon substrates could lead to similar molecular composition of refractory DOM. Here, we conducted microbial incubation experiments using four typically bioavailable substrates (L‐alanine, trehalose, sediment DOM extract, and diatom lysate) to investigate how exogenous substrates are transformed by a natural microbial assemblage. The results showed that although each‐substrate‐amendment induced different changes in the initial microbial assemblage and the amended substrates were almost depleted after 90 days of dark incubation, the bacterial community compositions became similar in all incubations on day 90. Correspondingly, revealed by ultra‐high resolution mass spectrometry, molecular composition of DOM in all incubations became compositionally consistent with recalcitrant DOM and similar toward that of DOM from the deep‐sea. These results indicate that while the composition of natural microbial communities can shift with substrate exposures, long‐term microbial transformation of distinct substrates can ultimately lead to a similar refractory DOM composition. These findings provide an explanation for the homogeneous and refractory features of deep‐sea DOM.

Mortality burden caused by diurnal temperature range: a nationwide time-series study in 364 Chinese locations - Min Cai; Jianxiong Hu; Chunliang Zhou; Zhulin Hou; Yanjun Xu; Maigeng Zhou; Yize Xiao; Biao Huang; Xiaojun Xu; Lifeng Lin; Tao Liu; Jianpeng Xiao; et al. (Stochastic Environmental Research and Risk Assessment, 2021)

Decoding Cortical Glial Cell Development - Xiaosu Li; Guoping Liu; Lin Yang; Zhenmeiyu Li; Zhuangzhi Zhang; Zhejun Xu; Yuqun Cai; Heng Du; Zihao Su; Ziwu Wang; Yangyang Duan; Haotian Chen; et al. (Neuroscience Bulletin, 2021)
Mouse cortical radial glial cells (RGCs) are primary neural stem cells that give rise to cortical oligodendrocytes, astrocytes, and olfactory bulb (OB) GABAergic interneurons in late embryogenesis. There are fundamental gaps in understanding how these diverse cell subtypes are generated. Here, by combining single-cell RNA-Seq with intersectional lineage analyses, we show that beginning at around E16.5, neocortical RGCs start to generate ASCL1 + EGFR + apical multipotent intermediate progenitors (MIPCs), which then differentiate into basal MIPCs that express ASCL1, EGFR, OLIG2, and MKI67. These basal MIPCs undergo several rounds of divisions to generate most of the cortical oligodendrocytes and astrocytes and a subpopulation of OB interneurons. Finally, single-cell ATAC-Seq supported our model for the genetic logic underlying the specification and differentiation of cortical glial cells and OB interneurons. Taken together, this work reveals the process of cortical radial glial cell lineage progression and the developmental origins of cortical astrocytes and oligodendrocytes.

Population-based meta-analysis of chloroquine: informing chloroquine pharmacokinetics in COVID-19 patients - Xueting Yao; Xiaoyu Yan; Xiaohan Wang; Ting Cai; Shun Zhang; Cheng Cui; Xiaoxu Wang; Zhe Hou; Qi Liu; Haiyan Li; Jing Lin; Zi Xiong; et al. (European Journal of Clinical Pharmacology, 2021)
Aims Chloroquine (CQ) has been repurposed to treat coronavirus disease 2019 (COVID-19). Understanding the pharmacokinetics (PK) in COVID-19 patients is essential to study its exposure–efficacy/safety relationship and provide a basis for a possible dosing regimen optimization. Subject and methods In this study, we used a population-based meta-analysis approach to develop a population PK model to characterize the CQ PK in COVID-19 patients. An open-label, single-center study (ethical review approval number: PJ-NBEY-KY-2020-063-01) was conducted to assess the safety, efficacy, and pharmacokinetics of CQ in patients with COVID-19. The sparse PK data from 50 COVID-19 patients, receiving 500 mg CQ phosphate twice daily for 7 days, were combined with additional CQ PK data from 18 publications. Results A two-compartment model with first-order oral absorption and first-order elimination and an absorption lag best described the data. Absorption rate (ka) was estimated to be 0.559 h −1 , and a lag time of absorption (ALAG) was estimated to be 0.149 h. Apparent clearance (CL/F) and apparent central volume of distribution (V2/F) was 33.3 l/h and 3630 l. Apparent distribution clearance (Q/F) and volume of distribution of peripheral compartment (Q3/F) were 58.7 l/h and 5120 l. The simulated CQ concentration under five dosing regimens of CQ phosphate were within the safety margin (400 ng/ml). Conclusion Model-based simulation using PK parameters from the COVID-19 patients shows that the concentrations under the currently recommended dosing regimen are below the safety margin for side-effects, which suggests that these dosing regimens are generally safe. The derived population PK model should allow for the assessment of pharmacokinetics–pharmacodynamics (PK-PD) relationships for CQ when given alone or in combination with other agents to treat COVID-19.

The relationship between ambient temperature and acute respiratory and cardiovascular diseases in Shenyang, China - Yang Shen; Xudong Zhang; Cai Chen; Qianqian Lin; Xiyuan Li; Wenxiu Qu; Xuejian Liu; Li Zhao; Shijie Chang (Environmental Science and Pollution Research, 2021)

Crenobacter intestini sp. nov., Isolated from the Intestinal Tract of Konosirus punctatus - Song-Biao Shi; Jia-Fa Wu; Li-Fang Yang; Ming-Guo Jiang; Cai-Mi Gao; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2021)

Relative contributions of global warming, AMO and IPO to the land precipitation variabilities since 1930s - Li Tao; X. San Liang; Lin Cai; Jiuwei Zhao; Meng Zhang (Climate Dynamics, 2021)

Mapping paddy rice using Landsat time series data in the Ganfu Plain irrigation system, Southern China, from 1988−2017 - Jingjing Cao; Xueliang Cai; Junwei Tan; Yuanlai Cui; Hengwang Xie; Fangping Liu; Lin Yang; Yufeng Luo (International Journal of Remote Sensing, 2021)

Seasonal variations in the water residence time in the Bohai Sea using 3D hydrodynamic model study and the adjoint method - Chongxin Luo; Lei Lin; Jie Shi; Zhe Liu; Zhongya Cai; Xinyu Guo; Huiwang Gao (Ocean Dynamics, 2021)

Projections from Infralimbic Cortex to Paraventricular Thalamus Mediate Fear Extinction Retrieval - Yan Tao; Cheng-Yun Cai; Jia-Yun Xian; Xiao-Lin Kou; Yu-Hui Lin; Cheng Qin; Hai-Yin Wu; Lei Chang; Chun-Xia Luo; Dong-Ya Zhu (Neuroscience Bulletin, 2021)

Astrocyte-Derived Lactate Modulates the Passive Coping Response to Behavioral Challenge in Male Mice - Ya-Nan Yin; Jian Hu; Yi-Li Wei; Ze-Lin Li; Zhou-Cai Luo; Rui-Qi Wang; Ke-Xin Yang; Shu-Ji Li; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2021)

Improved control of Frankliniella occidentalis on greenhouse pepper through the integration of Orius sauteri and neonicotinoid insecticides - Qing-cai Lin; Hao Chen; Dirk Babendreier; Jin-ping Zhang; Feng Zhang; Xiao-yan Dai; Zuo-wen Sun; Zhao-peng Shi; Xiao-lin Dong; Guang-an Wu; Yi Yu; Li Zheng; et al. (Journal of Pest Science, 2021)

Amniotic fluid mesenchymal stem cells repair mouse corneal cold injury by promoting mRNA N4-acetylcytidine modification and ETV4/JUN/CCND2 signal axis activation - Xinfeng Fei; Yuying Cai; Feng Lin; Yongyi Huang; Te Liu; Yan Liu (Human Cell, 2021)
Severe corneal injury is one of the main causes of loss of visual function. Mesenchymal stem cells (MSCs) have the ability to repair damaged cells in vivo. The present study aimed to explore whether MSCs could function as a cell therapy tool to replace traditional methods to treat corneal injury. CD44 + /CD105 + mesenchymal stem cells isolated from mouse amniotic fluid (mAF-MSCs) were injected into mice after cryoinjury to induce corneal endothelial cell injury. Histopathological assays indicated that mAF-MSCs could promote the growth of corneal epithelial cells, reduce keratitis, and repair the corneal damage caused by low temperature. cDNA microarray analysis revealed that the mAF-MSCs affected the expression patterns of mRNAs related to cell proliferation and differentiation pathways in the mice after transplantation. The results of quantitative real-time PCR and western blotting revealed that NAT12, NAT10, and the ETV4/JUN/CCND2 signaling axis were elevated significantly in the mAF-MSC-transplantation group, compared with those in the phosphate-buffered saline-treated groups. High performance liquid chromatography–mass spectroscopy results revealed that mAF-MSCs could promote mRNA N4-acetylcytidine (ac4C) modification and high expression of N -acetyltransferase in the eyeballs. RNA immunoprecipitation-PCR results showed that a specific product comprising Vegfa , Klf4 , Ccnd2 , Jun , and Etv4 mRNA specific coding region sites could be amplified using PCR from complexes formed in mAF-MSC-transplanted samples cross-linked with anti-ac4C antibodies. Thus, mouse amniotic fluid MSCs could repair the mouse corneal cold injury by promoting the ETV4/JUN/CCND2 signal axis activation and improving its stability by stimulating N4-acetylcytidine modification of their mRNAs.

Association between postnatal second-hand smoke exposure and ADHD in children: a systematic review and meta-analysis - Anyan Huang; Kusheng Wu; Zemin Cai; Yuhang Lin; Xuanzhi Zhang; Yanhong Huang (Environmental Science and Pollution Research, 2021)

A DEM fusion method for ascending and descending orbit StereoSAR DEMs in complicated mountain areas considering SAR echo intensity - Guo-lin Cai; Dong Shen; Ao-li Zhang; Hai-hua Yu; Xuan-yu Zhang (Journal of Mountain Science, 2021)

Determination and Comparison of the Solubility, Oil–Water Partition Coefficient, Intestinal Absorption, and Biliary Excretion of Carvedilol Enantiomers - Qi Zhang; Xin Wang; Hongjiao Xue; Baolin Huang; Zimin Lin; Zheng Cai (AAPS PharmSciTech, 2021)

Uncovering the mysterious identity of Taisui—an old Chinese folk legend - Erwei Li; Jinwei Ren; Qian Chen; Hanxing Zhang; Bin Lin; Hui Zhang; Shumin Zhang; Xiaoling Zhang; Lei Cai; Xingzhong Liu (Science China Life Sciences, 2020)

Effects of Short-Term Application of Chemical and Organic Fertilizers on Bacterial Diversity of Cornfield Soil in a Karst Area - Ying Li; Xiuming Liu; Lin Zhang; Yuanhuan Xie; Xianli Cai; Shijie Wang; Bin Lian (Journal of Soil Science and Plant Nutrition, 2020)

Evaluations of the serological test in the diagnosis of 2019 novel coronavirus (SARS-CoV-2) infections during the COVID-19 outbreak - Dachuan Lin; Lei Liu; Mingxia Zhang; Yunlong Hu; Qianting Yang; Jiubiao Guo; Youchao Dai; Yuzhong Xu; Yi Cai; Xinchun Chen; Kaisong Huang; Zheng Zhang (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Improved Brassica oleracea JZS assembly reveals significant changing of LTR-RT dynamics in different morphotypes - Xu Cai; Jian Wu; Jianli Liang; Runmao Lin; Kang Zhang; Feng Cheng; Xiaowu Wang (Theoretical and Applied Genetics, 2020)

Divergence in flowering time is a major component contributing to reproductive isolation between two wild rice species (Oryza rufipogon and O. nivara) - Xun Xu; Qing-Lin Meng; Mu-Fan Geng; Ning-Ning Ren; Lian Zhou; Yu-Su Du; Zhe Cai; Mei-Xia Wang; Xin Wang; Xiu-Hua Wang; Jing-Dan Han; Shuai Jiang; et al. (Science China Life Sciences, 2020)

Prenatal diagnosis of 22q11.2 copy number abnormalities in fetuses via single nucleotide polymorphism array - Meiying Cai; Na Lin; Linjuan Su; Xiaoqing Wu; Xiaorui Xie; Ying Li; Yuan Lin; Hailong Huang; Liangpu Xu (Molecular Biology Reports, 2020)
The q11.2 region on chromosome 22 contains numerous low-copy repeats that lead to deleted or duplicated regions in the chromosome, thereby resulting in different syndromes characterized by intellectual disabilities or congenital anomalies. The association between patient phenotypes and 22q11.2 copy number abnormalities has been previously described in postnatal cases; however, these features have not been systematically evaluated in prenatal cases because of limitations in phenotypic identification in prenatal testing. In this study, we investigated the detection rate of 22q11.2 copy number abnormalities in 2500 fetuses using single nucleotide polymorphism (SNP) array and determined the common abnormal ultrasound findings in fetuses carrying the 22q11.2 copy number abnormalities. The 22q11.2 copy number abnormalities were identified in 13 fetuses with cardiovascular malformations (6/13), kidney malformations (3/13), isolated ultrasound markers (3/13), or high-risk Down syndrome based on maternal serum screening (1/13). Approximately 0.5% (13/2500) of the fetuses harbored 22q11.2 copy number abnormalities. The most frequent ultrasound findings in fetuses with these abnormalities were cardiovascular malformations, followed by kidney malformations and isolated ultrasound markers. Prenatal diagnosis of these genetic abnormalities allows for the delineation of differential diagnoses, characterization of a wide spectrum of associated malformations, and determination of associations that exist between prenatal diagnosis and obstetrical outcomes.

A novel peroxiredoxin from the antagonistic endophytic bacterium Enterobacter sp. V1 contributes to cotton resistance against Verticillium dahliae - Lin Zhang; Ye Tao; Suya Zhao; Xiaoyan Yin; Junmei Chen; Miao Wang; Yingfan Cai; Qiuhong Niu (Plant and Soil, 2020)

Three new species of Terriera (Rhytismatales, Ascomycota) from China - Shu-Rui Cai; Shi-Juan Wang; Tu Lv; Cheng-Lin Hou (Mycological Progress, 2020)

Genome-wide identification of the Sec-dependent secretory protease genes in Erwinia amylovora and analysis of their expression during infection of immature pear fruit - Wang-bin Zhang; Hai-lin Yan; Zong-cai Zhu; Chao Zhang; Pei-xiu Du; Wen-jun Zhao; Wei-min Li (Journal of Zhejiang University-SCIENCE B, 2020)

Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study - Shao-rui Hao; Ren Yan; Shan-yan Zhang; Jiang-shan Lian; Huan Cai; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

CO2 flux of soil respiration in natural recovering karst abandoned farmland in Southwest China - Yanwei Wang; Weijun Luo; Guangneng Zeng; Hanling Yang; Meifang Wang; Yina Lyu; Anyun Cheng; Lin Zhang; Xianli Cai; Jia Chen; Shijie Wang (Acta Geochimica, 2020)

Relationship Between Seismic Moment and Source Duration for Seismogenic Earthquakes in Taiwan: Implications for the Product of Static Stress Drop and the Cube of Rupture Velocity - Ruey-Der Hwang; Cheng-Ying Ho; Tzu-Wei Lin; Wen-Yen Chang; Yi-Ling Huang; Cai-Yi Lin; Chiung-Yao Lin (Pure and Applied Geophysics, 2020)

Metabolomics analysis of nitrogen-containing metabolites between two Dendrobium plants - Cheng Song; Chunyan Jiao; Qing Jin; Cunwu Chen; Yongping Cai; Yi Lin (Physiology and Molecular Biology of Plants, 2020)

Biological activity and safety profile of monoterpenes against Plutella xylostella L. (Lepidoptera: Plutellidae) - Yuehong Cai; Xian Hu; Pan Wang; Yongjian Xie; Zhufeng Lin; Zhilin Zhang (Environmental Science and Pollution Research, 2020)

Modeling the Impacts of Nitrogen Dynamics on Regional Terrestrial Carbon and Water Cycles over China with Noah-MP-CN - Jingjing Liang; Zong-Liang Yang; Xitian Cai; Peirong Lin; Hui Zheng; Qingyun Bian (Advances in Atmospheric Sciences, 2020)

GPI7‐mediated glycosylphosphatidylinositol anchoring regulates appressorial penetration and immune evasion during infection of Magnaporthe oryzae - Caiyun Liu; Junjie Xing; Xuan Cai; Ahmed Hendy; Wenhui He; Jun Yang; Junbing Huang; You‐Liang Peng; Lauren Ryder; Xiao‐Lin Chen (Environmental Microbiology, 2020)
Summary Glycosylphosphatidylinositol (GPI) anchoring plays key roles in many biological processes by targeting proteins to the cell wall; however, its roles are largely unknown in plant pathogenic fungi. Here, we reveal the roles of the GPI anchoring in Magnaporthe oryzae during plant infection. The GPI‐anchored proteins were found to highly accumulate in appressoria and invasive hyphae. Disruption of GPI7 , a GPI anchor‐pathway gene, led to a significant reduction in virulence. The Δ gpi7 mutant showed significant defects in penetration and invasive growth. This mutant also displayed defects of the cell wall architecture, suggesting GPI7 is required for cell wall biogenesis. Removal of GPI‐anchored proteins in the wild‐type strain by hydrofluoric acid (HF) pyridine treatment exposed both the chitin and β‐1,3‐glucans to the host immune system. Exposure of the chitin and β‐1,3‐glucans was also observed in the Δ gpi7 mutant, indicating GPI‐anchored proteins are required for immune evasion. The GPI anchoring can regulate subcellular localization of the Gel proteins in the cell wall for appressorial penetration and abundance of which for invasive growth. Our results indicate the GPI anchoring facilitates the penetration of M. oryzae into host cells by affecting the cell wall integrity and the evasion of host immune recognition.

Perilipin LDP1 coordinates lipid droplets formation and utilization for appressorium‐mediated infection in Magnaporthe oryzae - Xuan Cai; Jingjing Yan; Caiyun Liu; Junjie Xing; Zhiyong Ren; Ahmed Hendy; Lu Zheng; Junbin Huang; Xiao‐Lin Chen (Environmental Microbiology, 2020)
Summary Lipid droplets (LDs) serve as one of the major reservoirs in conidia of Magnaporthe oryzae and are quickly utilized during appressorium formation. Here, we identified a gene, LDP1 , encoding a perilipin that is important for LD formation and utilization during appressorium maturation. LDP1 is highly expressed in conidium and immature appressorium. Disruption mutants of LDP1 were significantly reduced in virulence, due to appressorial turgor reduction and difficulty in penetration. LDs were significantly reduced in the Δ ldp1 mutant, indicating LDP1 was required for LDs formation. LDP1 was colocalized with the LDs in conidium and immature appressorium but was gradually separated during appressorium maturation. A typical intracellular triacylglycerol lipase, TGL1‐2, was clearly separated with LDs in conidium and immature appressorium but was well colocalized with LDs during appressorium maturation. The subcellular localization of TGL1‐2 was affected by LDP1. These data suggested that LDP1 was bound to LDs for protecting from utilization in conidia and at the early appressorium stage but was separated from LDs for lipase entering and degradation. LDP1 was phosphorylated by CPKA at Thr96, which was essential for its localization and functions. These data indicate perilipin LDP1 can coordinate LD formation and utilization for appressorium‐mediated infection of M . oryzae .

Identification of PP2A and S6 Kinase as Modifiers of Leucine-Rich Repeat Kinase-Induced Neurotoxicity - Joan Poh Ling Sim; Wang Ziyin; Adeline Henry Basil; Shuping Lin; Zhongcan Chen; Chengwu Zhang; Li Zeng; Yu Cai; Kah-Leong Lim (NeuroMolecular Medicine, 2020)
Mutations in LRRK2 are currently recognized as the most common monogenetic cause of Parkinsonism. The elevation of kinase activity of LRRK2 that frequently accompanies its mutations is widely thought to contribute to its toxicity. Accordingly, many groups have developed LRRK2-specific kinase inhibitors as a potential therapeutic strategy. Given that protein phosphorylation is a reversible event, we sought to elucidate the phosphatase(s) that can reverse LRRK2-mediated phosphorylation, with the view that targeting this phosphatase(s) may similarly be beneficial. Using an unbiased RNAi phosphatase screen conducted in a Drosophila LRRK2 model, we identified PP2A as a genetic modulator of LRRK2-induced neurotoxicity. Further, we also identified ribosomal S6 kinase (S6K), a target of PP2A, as a novel regulator of LRRK2 function. Finally, we showed that modulation of PP2A or S6K activities ameliorates LRRK2-associated disease phenotype in Drosophila .

Grenville-age orogenic event along the northeastern margin of the Quanji massif, NW China: constraints from ~1.1 Ga migmatite - Zhouxuan Xiao; Licheng Ma; Wan Jiang; Ran Wang; Yuyan Yao; Jie Cai; Jingyu Lin; Lu Li (Geosciences Journal, 2020)

Clinical strategies for differentiating IgG4-related cholecystitis from gallbladder carcinoma to avoid unnecessary surgical resection - Rui Zhang; Hao-Ming Lin; Zhao-Xi Cai; Su-Juan Du; Hong Zeng; Lei-Bo Xu; Jie Wang; Chao Liu (Science China Life Sciences, 2020)

Comparison of epidemiological and clinical characteristics of COVID-19 patients with and without Wuhan exposure - Jiang-shan Lian; Huan Cai; Shao-rui Hao; Xi Jin; Xiao-li Zhang; Lin Zheng; Hong-yu Jia; Jian-hua Hu; Shan-yan Zhang; Guo-dong Yu; Jue-qing Gu; Chan-yuan Ye; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

An overview of COVID-19 - Yu Shi; Gang Wang; Xiao-peng Cai; Jing-wen Deng; Lin Zheng; Hai-hong Zhu; Min Zheng; Bo Yang; Zhi Chen (Journal of Zhejiang University-SCIENCE B, 2020)

Opportunistic bacteria use quorum sensing to disturb coral symbiotic communities and mediate the occurrence of coral bleaching - Jin Zhou; Zi‐Jun Lin; Zhong‐Hua Cai; Yan‐Hua Zeng; Jian‐Ming Zhu; Xiao‐Peng Du (Environmental Microbiology, 2020)
Summary Coral associated microorganisms, especially some opportunistic pathogens can utilize quorum‐sensing (QS) signals to affect population structure and host health. However, direct evidence about the link between coral bleaching and dysbiotic microbiomes under QS regulation was lacking. Here, using 11 opportunistic bacteria and their QS products (AHLs, acyl‐homoserine‐lactones), we exposed Pocillopora damicornis to three different treatments: test groups (A and B: mixture of AHLs‐producing bacteria and cocktail of AHLs signals respectively); control groups (C and D: group A and B with furanone added respectively); and a blank control (group E: only seawater) for 21 days. The results showed that remarkable bleaching phenomenon was observed in groups A and B. The operational taxonomic units‐sequencing analysis shown that the bacterial network interactions and communities composition were significantly changed, becoming especially enhanced in the relative abundances of Vibrio , Edwardsiella , Enterobacter , Pseudomonas , and Aeromonas . Interestingly, the control groups (C and D) were found to have a limited influence upon host microbial composition and reduced bleaching susceptibility of P. damicornis . These results indicate bleaching's initiation and progression may be caused by opportunistic bacteria of resident microbes in a process under regulation by AHLs. These findings add a new dimension to our understanding of the complexity of bleaching mechanisms from a chemoecological perspective.

Co-infections of SARS-CoV-2 with multiple common respiratory pathogens in infected patients - Dachuan Lin; Lei Liu; Mingxia Zhang; Yunlong Hu; Qianting Yang; Jiubiao Guo; Yongchao Guo; Youchao Dai; Yuzhong Xu; Yi Cai; Xinchun Chen; Zheng Zhang; et al. (Science China Life Sciences, 2020)

Immunogenicity noninferiority study of 2 doses and 3 doses of an Escherichia coli-produced HPV bivalent vaccine in girls vs. 3 doses in young women - Yue-Mei Hu; Meng Guo; Chang-Gui Li; Kai Chu; Wen-Gang He; Jing Zhang; Jian-Xiang Gu; Juan Li; Hui Zhao; Xiang-Hong Wu; BiZhen Lin; Zhi-Jie Lin; et al. (Science China Life Sciences, 2020)

Heat stress induces apoptosis through disruption of dynamic mitochondrial networks in dairy cow mammary epithelial cells - Kun-Lin Chen; Hui-Li Wang; Lin-Zheng Jiang; Yong Qian; Cai-Xia Yang; Wei-Wei Chang; Ji-Feng Zhong; Guang-Dong Xing (In Vitro Cellular & Developmental Biology - Animal, 2020)

ANN Model Development for Air Permeability in Biochar Amended Unsaturated Soil - Weiling Cai; Himanshu Kumar; Shan Huang; Sanandam Bordoloi; Ankit Garg; Peng Lin; Phani Gopal (Geotechnical and Geological Engineering, 2020)

Correction to: Competitive sequestration of Ni(II) and Eu(III) on montmorillonite: role of molar Ni:Eu ratios and coexisting oxalate - Lin Xu; Wei Liu; Yawen Cai; Chunfang Wu; Lei Chen; Shitong Yang; Xiangke Wang; Guoxun Ji; Shuao Wang (Environmental Science and Pollution Research, 2020)

Impacts of elevated temperature and pCO2 on the brooded larvae of Pocillopora damicornis from Luhuitou Reef, China: evidence for local acclimatization - Lei Jiang; Ming-Lan Guo; Fang Zhang; Yu-Yang Zhang; Guo-Wei Zhou; Xin-Ming Lei; Xiang-Cheng Yuan; You-Fang Sun; Tao Yuan; Lin Cai; Jian-Sheng Lian; Sheng Liu; et al. (Coral Reefs, 2020)

NLRP3 Deficiency Attenuates Secondary Degeneration of Visual Cortical Neurons Following Optic Nerve Injury - Zhou Zhang; Wenyi Liu; Yubin Huang; Linlin Luo; Xiaofeng Cai; Yunjia Liu; Liqianyu Ai; Jun Yan; Sen Lin; Jian Ye (Neuroscience Bulletin, 2020)

Interspecific interactions in dual-species biofilms of soil bacteria: effects of fertilization practices - Xiaojie Sun; Peng Cai; Søren J. Sørensen; Monika Mortimer; Chunhui Gao; Qiaoyun Huang; Yiming Wang; Xiangui Lin; Yichao Wu; Di Zhu; Ruirui Chen (Journal of Soils and Sediments, 2020)

Southward subduction of the Bangong-Nujiang Tethys Ocean: insights from ca. 161–129 Ma arc volcanic rocks in the north of Lhasa terrane, Tibet - Yue Tang; Qing-Guo Zhai; Pei-Yuan Hu; Sun-Lin Chung; Xu-Chang Xiao; Hai-Tao Wang; Zhi-Cai Zhu; Wei Wang; Hao Wu; Hao-Yang Lee (International Journal of Earth Sciences, 2020)

Prolonged Neo-Tethyan magmatic arc in Myanmar: evidence from geochemistry and Sr–Nd–Hf isotopes of Cretaceous mafic–felsic intrusions in the Banmauk–Kawlin area - Jin-Xiang Li; Wei-Ming Fan; Li-Yun Zhang; Tou-Ping Peng; Ya-Li Sun; Lin Ding; Fu-Long Cai; Kyaing Sein (International Journal of Earth Sciences, 2020)

Transcriptome analysis of axillary bud differentiation in a new dual-axillary bud genotype of sugarcane - Dan Chen; Xin Lu; Xiaoyang Wu; Xiongmei Ying; Wenjie Long; Huosheng Su; Hongbo Liu; Xiuqin Lin; Chaohua Xu; Qing Cai (Genetic Resources and Crop Evolution, 2020)

Genetic diversity of oolong tea (Camellia sinensis) germplasms based on the nanofluidic array of single-nucleotide polymorphism (SNP) markers - Yi Lin; Wentao Yu; Lin Zhou; Xiaojing Fan; Feiquan Wang; Pengjie Wang; Wanping Fang; Chunping Cai; Naixing Ye (Tree Genetics & Genomes, 2020)

Variation of functional brain connectivity in epileptic seizures: an EEG analysis with cross-frequency phase synchronization - Haitao Yu; Lin Zhu; Lihui Cai; Jiang Wang; Chen Liu; Nan Shi; Jing Liu (Cognitive Neurodynamics, 2020)

Exploring global food security pattern from the perspective of spatio-temporal evolution - Jianming Cai; Enpu Ma; Jing Lin; Liuwen Liao; Yan Han (Journal of Geographical Sciences, 2020)

The acclimation of leaf photosynthesis of wheat and rice to seasonal temperature changes in T‐FACE environments - Chuang Cai; Gang Li; Lijun Di; Yunjie Ding; Lin Fu; Xuanhe Guo; Paul C. Struik; Genxing Pan; Haozheng Li; Weiping Chen; Weihong Luo; Xinyou Yin (Global Change Biology, 2020)
Crops show considerable capacity to adjust their photosynthetic characteristics to seasonal changes in temperature. However, how photosynthesis acclimates to changes in seasonal temperature under future climate conditions has not been revealed. We measured leaf photosynthesis ( A n ) of wheat ( Triticum aestivum L.) and rice ( Oryza sativa L.) grown under four combinations of two levels of CO 2 (ambient and enriched up to 500 µmol/mol) and two levels of canopy temperature (ambient and increased by 1.5–2.0°C) in temperature by free‐air CO 2 enrichment (T‐FACE) systems. Parameters of a biochemical C 3 ‐photosynthesis model and of a stomatal conductance ( g s ) model were estimated for the four conditions and for several crop stages. Some biochemical parameters related to electron transport and most g s parameters showed acclimation to seasonal growth temperature in both crops. The acclimation response did not differ much between wheat and rice, nor among the four treatments of the T‐FACE systems, when the difference in the seasonal growth temperature was accounted for. The relationships between biochemical parameters and leaf nitrogen content were consistent across leaf ranks, developmental stages, and treatment conditions. The acclimation had a strong impact on g s model parameters: when parameter values of a particular stage were used, the model failed to correctly estimate g s values of other stages. Further analysis using the coupled g s –biochemical photosynthesis model showed that ignoring the acclimation effect did not result in critical errors in estimating leaf photosynthesis under future climate, as long as parameter values were measured or derived from data obtained before flowering.

The Arabidopsis kinase-associated protein phosphatase KAPP, interacting with protein kinases SnRK2.2/2.3/2.6, negatively regulates abscisic acid signaling - Kai Lu; Ya-Dong Zhang; Chun-Fang Zhao; Li-Hui Zhou; Qing-Yong Zhao; Tao Chen; Cai-Lin Wang (Plant Molecular Biology, 2020)

Synthesis of Carbon Dots and their Application as Turn Off–On Fluorescent Sensor for Mercury (II) and Glutathione - Lin Cai; Zheng Fu; Fengling Cui (Journal of Fluorescence, 2020)

Metallothionein induction attenuates the progression of lung injury in mice exposed to long-term intermittent hypoxia - Xingyu Lin; Rekha Jagadapillai; Jun Cai; Lu Cai; Guoguang Shao; Evelyne Gozal (Inflammation Research, 2020)

Mechanistic examination of methimazole-induced hepatotoxicity in patients with Grave’s disease: a metabolomic approach - Xuesong Li; Jialin Yang; Shasha Jin; Yu Dai; Yujuan Fan; Xiaofang Fan; Zhigang Li; Jianhua Yang; Wai-Ping Yau; Haishu Lin; Weimin Cai; Xiaoqiang Xiang (Archives of Toxicology, 2020)

Influence of salinity on the biological treatment of domestic ship sewage using an air-lift multilevel circulation membrane reactor - Yuhang Cai; Asad A. Zaidi; Yue Shi; Kun Zhang; Xin Li; Shihao Xiao; Aqiang Lin (Environmental Science and Pollution Research, 2019)

Fine-mapping QTLs and the validation of candidate genes for Aluminum tolerance using a high-density genetic map - Zhandong Cai; Yanbo Cheng; Peiqi Xian; Rongbin Lin; Qiuju Xia; Xueke He; Qiwen Liang; Tengxiang Lian; Qibin Ma; Hai Nian (Plant and Soil, 2019)

A new indole-type alkaloid from the roots of Clematis florida var. plena - Kai-Hui Sun; Xin-Hua Ma; Xian-Ming Zeng; Zhong-Yue Lin; Yu-Mei Cai; Hai-Tao Zhang; Xiao-Yan Lin; Shi-Biao Feng; Tian-Hua Zhong; Yong-Hong Zhang (Natural Product Research, 2019)

Adsorption Removal of Cr(VI) with Activated Carbon Prepared by Co-pyrolysis of Rice Straw and Sewage Sludge with ZnCl2 Activation - Liangqian Fan; Wenxin Wan; Xianda Wang; Jie Cai; Fenghui Chen; Wei Chen; Lin Ji; Hongbing Luo; Lin Cheng (Water, Air, & Soil Pollution, 2019)

Two-factor ANOVA of SSH and RNA-seq analysis reveal development-associated Pi-starvation genes in oilseed rape - Zhong-Wei Zhang; Ling-Yang Feng; Jian-Hui Wang; Yu-Fan Fu; Xin Cai; Chang-Quan Wang; Jun-Bo Du; Ming Yuan; Yang-Er Chen; Pei-Zhou Xu; Ting Lan; Guang-Deng Chen; et al. (Planta, 2019)

Three new Coccomyces species from Shennongjia National Nature Reserve in China - Tu Lv; Wan-Peng Tang; Shu-Rui Cai; Cheng-Lin Hou (Mycological Progress, 2019)

Discovery of a virus of the species Enterovirus F in goats - Xiaoran Chang; Qian Lin; Junying Hu; Xu Wang; Xin Li; Menglu Cai; Weiyu Wang; Zecai Zhang; Xinping Wang (Archives of Virology, 2019)

A new furostanol saponin from Dendrobium chrysanthum Lindl. with cytotoxic activity - Chao Yang; Weilong Lin; Lin Zhao; Jinyan Cai (Natural Product Research, 2019)

Identification and Expression Analysis of TCP Genes in Saccharum spontaneum L - Jishan Lin; Mengting Zhu; Mingxing Cai; Wenping Zhang; Mahpara Fatima; Haifeng Jia; Feifei Li; Ray Ming (Tropical Plant Biology, 2019)

Long term experimental drought alters community plant trait variation, not trait means, across three semiarid grasslands - Wentao Luo; Xiaoan Zuo; Robert J. Griffin-Nolan; Chong Xu; Wang Ma; Lin Song; Kenny Helsen; Yingchao Lin; Jiangping Cai; Qiang Yu; Zhengwen Wang; Melinda D. Smith; et al. (Plant and Soil, 2019)

Correction to: Particulate matter 2.5 induced arrhythmogenesis mediated by TRPC3 in human induced pluripotent stem cell-derived cardiomyocytes - Cheng Cai; Min Ling; Jiayi Huang; Yongping Lin; Weilun Miao; Pei Chen; Xing Chen; Jiaxian Wang; Minglong Chen; Qian Bian (Archives of Toxicology, 2019)

Four LysR-type transcriptional regulator family proteins (LTTRs) involved in antibiotic resistance in Aeromonas hydrophila - Yuying Fu; Qilan Cai; Yuqian Wang; Wanxin Li; Jing Yu; Guidi Yang; Wenxiong Lin; Xiangmin Lin (World Journal of Microbiology and Biotechnology, 2019)

Dynamics of MiRNA Transcriptome in Turbot (Scophthalmus maximus L.) Intestine Following Vibrio anguillarum Infection - Chengbin Gao; Xin Cai; Qiang Fu; Ning Yang; Lin Song; Baofeng Su; Fenghua Tan; Baining Liu; Chao Li (Marine Biotechnology, 2019)

Ocean Climate Observing Requirements in Support of Climate Research and Climate Information - Detlef Stammer; Annalisa Bracco; Krishna AchutaRao; Lisa Beal; Nathaniel L. Bindoff; Pascale Braconnot; Wenju Cai; Dake Chen; Matthew Collins; Gokhan Danabasoglu; Boris Dewitte; Riccardo Farneti; et al. (Frontiers in Marine Science, 2019)

Effect of pH on Pollutants Removal of Ship Sewage Treatment in an Innovative Aerobic-Anaerobic Micro-Sludge MBR System - Yuhang Cai; Teng Ben; Asad A. Zaidi; Yue Shi; Kun Zhang; Aqiang Lin; Chen Liu (Water, Air, & Soil Pollution, 2019)

The effects of early life polyunsaturated fatty acids and ruminant trans fatty acids on allergic diseases: A systematic review and meta-analysis - Weijia Wu; Lizi Lin; Bijun Shi; Jin Jing; Li Cai (Critical Reviews in Food Science and Nutrition, 2019)

Influence of design probe and sequence mismatches on the efficiency of fluorescent RPA - Xiaoqing Liu; Qiongying Yan; Jianfei Huang; Jing Chen; Zhengyang Guo; Zhongdong Liu; Lin Cai; Risheng Li; Yan Wang; Guowu Yang; Quanxue Lan (World Journal of Microbiology and Biotechnology, 2019)

Exosomal long non-coding RNAs: biological properties and therapeutic potential in cancer treatment - Jie Luo; Yan Xiong; Pei-fen Fu; En-chun Li; Lei Qu; Xiao Fan; Zhi-jian Cai; Ai-fu Lin (Journal of Zhejiang University-SCIENCE B, 2019)

Role of mTOR complex in IGF-1 induced neural differentiation of DPSCs - Dan Huang; Shuling Shen; Ming Cai; Lin Jin; Jun Lu; Ke Xu; Jinlong Zhang; Guijuan Feng; Yingzi Hu; Ke Zheng; Xingmei Feng (Journal of Molecular Histology, 2019)

Identification and validation of a novel major QTL for all-stage stripe rust resistance on 1BL in the winter wheat line 20828 - Jian Ma; Nana Qin; Ben Cai; Guoyue Chen; Puyang Ding; Han Zhang; Congcong Yang; Lin Huang; Yang Mu; Huaping Tang; Yaxi Liu; Jirui Wang; et al. (Theoretical and Applied Genetics, 2019)

Knockout of Atg5 inhibits proliferation and promotes apoptosis of DF-1 cells - Zhihong Liao; Zhenkai Dai; Chenyu Cai; Xinheng Zhang; Aijun Li; Huanmin Zhang; Yiming Yan; Wencheng Lin; Yu Wu; Hongxin Li; Haiyun Li; Qingmei Xie (In Vitro Cellular & Developmental Biology - Animal, 2019)

Mercury–Organic Matter Interactions in Soils and Sediments: Angel or Devil? - Mei He; Lei Tian; Hans Fredrik Veiteberg Braaten; Qingru Wu; Jie Luo; Li-Mei Cai; Jiang-Hui Meng; Yan Lin (Bulletin of Environmental Contamination and Toxicology, 2019)

Family-1 UDP glycosyltransferases in pear (Pyrus bretschneideri): Molecular identification, phylogenomic characterization and expression profiling during stone cell formation - Xi Cheng; Abdullah Muhammad; Guohui Li; Jingyun Zhang; Jun Cheng; Jingxiang Qiu; Taoshan Jiang; Qing Jin; Yongping Cai; Yi Lin (Molecular Biology Reports, 2019)

Particulate matter 2.5 induced arrhythmogenesis mediated by TRPC3 in human induced pluripotent stem cell-derived cardiomyocytes - Cheng Cai; Jiayi Huang; Yongping Lin; Weilun Miao; Pei Chen; Xing Chen; Jiaxian Wang; Minglong Chen (Archives of Toxicology, 2019)

Attribute recognition model for risk assessment of water inrush - Jing Wang; Shu-cai Li; Li-ping Li; Peng Lin; Zhen-hao Xu; Cheng-lu Gao (Bulletin of Engineering Geology and the Environment, 2019)