Characteristic analysis and improvement methods of the indoor thermal environment in post-disaster temporary residential buildings: A systematic review - Mingyuan Qin; Bee Teng Chew; Yat Huang Yau; Zhen Yang; Xiaofei Han; Li Chang; Yiqiao Liu; Song Pan (Building and Environment, 2023)

Facile Synthesis of Lanthanum-Doped Fe-Based MOF for Phosphate Removal from Water: High Adsorption Capacity, Tuneability, and Reproducibility - Yi Liu; Dengjie Zhong; Yunlan Xu; Haixing Chang; Lin Dong; Zhuofan Han; Jun Li; Nianbing Zhong (Water, Air, & Soil Pollution, 2023)

Biomarkers of aging - Hainan Bao; Jiani Cao; Mengting Chen; Min Chen; Wei Chen; Xiao Chen; Yanhao Chen; Yu Chen; Yutian Chen; Zhiyang Chen; Jagadish K. Chhetri; Yingjie Ding; et al. (Science China Life Sciences, 2023)

Montmorillonite-based aerogels assisted environmental remediation - Chang Liu; Zhizheng Li; Bing Li; Huacheng Zhang; Jie Han (Applied Clay Science, 2023)

Comparison of deterministic wind speed generation models for wind erosion modeling - Xue Han; Chunping Chang; Zhongling Guo; Shuiqing Yin; Jifeng Li; Huiru Li; Rende Wang; Qing Li (Agricultural and Forest Meteorology, 2023)

Linking seed size and number to trait syndromes in trees - Michal Bogdziewicz; Marie‐Claire Aravena Acuña; Robert Andrus; Davide Ascoli; Yves Bergeron; Daniel Brveiller; Thomas Boivin; Raul Bonal; Thomas Caignard; Maxime Cailleret; Rafael Calama; Sergio Donoso Calderon; et al. (Global Ecology and Biogeography, 2023)
Aim Our understanding of the mechanisms that maintain forest diversity under changing climate can benefit from knowledge about traits that are closely linked to fitness. We tested whether the link between traits and seed number and seed size is consistent with two hypotheses, termed the leaf economics spectrum and the plant size syndrome, or whether reproduction represents an independent dimension related to a seed size–seed number trade‐off. Location Most of the data come from Europe, North and Central America and East Asia. A minority of the data come from South America, Africa and Australia. Time period 1960–2022. Major taxa studied Trees. Methods We gathered 12 million observations of the number of seeds produced in 784 tree species. We estimated the number of seeds produced by individual trees and scaled it up to the species level. Next, we used principal components analysis and generalized joint attribute modelling (GJAM) to map seed number and size on the tree traits spectrum. Results Incorporating seed size and number into trait analysis while controlling for environment and phylogeny with GJAM exposes relationships in trees that might otherwise remain hidden. Production of the large total biomass of seeds [product of seed number and seed size; hereafter, species seed productivity (SSP)] is associated with high leaf area, low foliar nitrogen, low specific leaf area (SLA) and dense wood. Production of high seed numbers is associated with small seeds produced by nutrient‐demanding species with softwood, small leaves and high SLA. Trait covariation is consistent with opposing strategies: one fast‐growing, early successional, with high dispersal, and the other slow‐growing, stress‐tolerant, that recruit in shaded conditions. Main conclusions Earth system models currently assume that reproductive allocation is indifferent among plant functional types. Easily measurable seed size is a strong predictor of the seed number and species seed productivity. The connection of SSP with the functional traits can form the first basis of improved fecundity prediction across global forests.

Analysis of natural disasters and energy efficiency in China - Zhong Fang; Yung-ho Chiu; Tai-Yu Lin; Tzu-Han Chang; Yi-Nuo Lin (Environment, Development and Sustainability, 2023)

Changes of dissolved organic matter fractions and formation of oxidation byproducts during electrochemical treatment of landfill leachates: Development of spectroscopic indicators for process optimization - Bi-Cun Jiang; Ye-Chao Tian; Ai-Min Li; Yu-Ze Han; Ze-Tao Wu; Chang Lu; Hai-Ou Song; Rong Ji; Wen-Tao Li; Gregory V. Korshin (Water Research, 2023)

Ecological security evaluation and early warning in the water source area of the Middle Route of South-to-North Water Diversion Project - Ken Sun; Wenbo He; Yufang Shen; Tianshu Yan; Chang Liu; Zhenzhen Yang; Jingmin Han; Weisheng Xie (Science of The Total Environment, 2023)

Foaming properties of dried egg white at different outlet temperatures - Junhua Li; Jinjing Sun; Luping Gu; Yujie Su; Yanjun Yang; Cuihua Chang; Qi Han (Journal of Food Engineering, 2023)

Tracking the life-cycle greenhouse gas emissions of municipal solid waste incineration power plant: A case study in Shanghai - Xiaoqu Han; Hongzhang Chang; Chuan Wang; Jun Tai; Sotirios Karellas; Junjie Yan; Lijie Song; Zhujie Bi (Journal of Cleaner Production, 2023)

Remediation of the black-odor water body by aquatic plants with plant growth-promoting Rhizobacteria: Lab and pilot tests - Bing Xu; Xiaoyuan Zhang; Jo-Shu Chang; Hongliang Guo; Song Han; Duu-Jong Lee (Environmental Research, 2023)

Severe shoot topping slows down berry sugar accumulation rate, alters the vine growth and photosynthetic capacity, and influences the flavoromics of Cabernet Sauvignon grapes in a semi-arid region - Hao-Cheng Lu; Meng-Bo Tian; Ning Shi; Xiao Han; Hui-Qing Li; Chi-Fang Cheng; Wu Chen; Shu-De Li; Fei He; Chang-Qing Duan; Jun Wang (European Journal of Agronomy, 2023)

Co-contaminants of ethinylestradiol and sulfamethoxazole in groundwater exacerbate ecotoxicity and ecological risk and compromise the energy budget of C. elegans - Yu-Hsuan Kuo; Chun Ming How; Chi-Wei Huang; Pei-Ling Yen; Chan-Wei Yu; Chun-Han Chang; Vivian Hsiu-Chuan Liao (Aquatic Toxicology, 2023)

Corticostriatal Projections Relying on GABA Levels Mediate Exercise-Induced Functional Recovery in Cerebral Ischemic Mice - Ying Xing; Anjing Zhang; Congqin Li; Jing Han; Jun wang; Lu Luo; Xuechun Chang; Zhanzhuang Tian; Yulong Bai (Molecular Neurobiology, 2023)

Machine learning in establishing the stage–discharge rating curve of an irrigation canal - Yen-Chang Chen; Han-Chung Yang; Shin-Ping Lee; Cheng-Hsuan Ho (Paddy and Water Environment, 2023)

Tunable nanochannel resistive pulse sensing device using a novel multi-module self-assembly - Wenwei Pan; Rui You; Shuaihua Zhang; Ye Chang; Feng Zhou; Quanning Li; Xuejiao Chen; Xuexin Duan; Ziyu Han (Analytica Chimica Acta, 2023)

Algae-mediated bioremediation of ciprofloxacin through a symbiotic microalgae-bacteria consortium - Yue Wang; Weihao Ning; Meina Han; Changfei Gao; Wanqian Guo; Jo-Shu Chang; Shih-Hsin Ho (Algal Research, 2023)

Grape polysaccharides: compositional changes in grapes and wines, possible effects on wine organoleptic properties, and practical control during winemaking - Si-Yu Li; Chang-Qing Duan; Zhen-Hai Han (Critical Reviews in Food Science and Nutrition, 2023)

The Cost of Forest Thinning Operations in the Western United States: A Systematic Literature Review and New Thinning Cost Model - Heesol Chang; Han-Sup Han; Nathaniel Anderson; Yeon-Su Kim; Sang-Kyun Han (Journal of Forestry, 2023)
Mechanical forest thinning treatments are implemented across the western United States (US) to improve forest health and reduce hazardous fuels. However, the main challenge in thinning operations is low financial feasibility. This study synthesized the stump-to-truck cost of forest thinning operations in the western US based on operations research articles published over the last 40 years (1980–2020). We systematically selected and reviewed 20 thinning studies to analyze key variables affecting machine productivity and harvesting costs. The average cost of forest thinning was lowest for a mechanized whole-tree thinning operation at $21.34/ton or $2,075/ha. Feller-bunchers and skidders showed the highest productivity in felling and extraction machines, respectively. We found that extraction cost accounted for the largest proportion of the stump-to-truck cost of forest thinning (33%, 43%, and 34% in whole-tree, tree-length, and cut-to-length thinning, respectively). Tree diameter and machine travel distance are common variables affecting thinning productivity and thus cost, regardless of the harvesting methods used. With thinning productivity and cost data from the selected studies, we developed a spreadsheet-based model to estimate thinning costs for various harvesting systems. This literature synthesis and new thinning cost model can help foresters develop a cost-effective plan for thinning operations.

Flexible guided anti-collision device for bridge pier protection against ship collision: Numerical simulation and ship collision field test - Fei Wang; Hui-Juan Chang; Bo-Han Ma; Yong-Gang Wang; Li-Ming Yang; Jun Liu; Xin-Long Dong (Ocean Engineering, 2023)

Concomitant oxidation of fatty acids other than DHA and EPA plays a role in the characteristic off-odor of fish oil - Yun-Qi Wen; Chang-Hu Xue; Hong-Wei Zhang; Li-Li Xu; Xiao-Han Wang; Shi-Jie Bi; Qian-Qian Xue; Yong Xue; Zhao-Jie Li; Joaquín Velasco; Xiao-Ming Jiang (Food Chemistry, 2023)

Integrative mRNA-miRNA interaction analysis associated with the immune response of Strongylocentrotus intermedius to Vibrio harveyi infection - Pengfei Hao; Lingshu Han; Zijiao Quan; Xin Jin; Yuanxin Li; Yanglei Wu; Xianglei Zhang; Wenpei Wang; Chuang Gao; Luo Wang; Heng Wang; Weijie Zhang; et al. (Fish & Shellfish Immunology, 2023)

Effect mechanism of block convexity on the shear behaviors of soil-rock mixtures by the developed 3D spherical harmonics-based modeling approach - Han Zhang; Xinli Hu; Lehua Wang; Erping Zhao; Chang Liu (Computers and Geotechnics, 2023)

Chronological implications of changes in the accumulation rate of long marine cores from the continental shelf, southeastern Korea - Hyun Ho Yoon; Jin Cheul Kim; Dong-Geun Yoo; Chang-Pyo Jun; Gwang-Soo Lee; Seok-Hwi Hong; Han-Woo Choi (Marine Geophysical Research, 2023)

Classifying Temporomandibular Disorder with Artificial Intelligent Architecture Using Magnetic Resonance Imaging - Zih-Kai Kao; Neng-Tai Chiu; Hung-Ta Hondar Wu; Wan-Chen Chang; Ding-Han Wang; Yen-Ying Kung; Pei-Chi Tu; Wen-Liang Lo; Yu-Te Wu (Annals of Biomedical Engineering, 2023)

A Data-Driven Intelligent Prediction Approach for Collision Responses of Honeycomb Reinforced Pipe Pile of the Offshore Platform - Lei Yang; Hong Lin; Chang Han; Hassan Karampour; Haochen Luan; Pingping Han; Hao Xu; Shuo Zhang (Journal of Marine Science and Engineering, 2023)
The potential collision between the ship and the pipe piles of the jacket structure brings huge risks to the safety of an offshore platform. Due to their high energy-absorbing capacity, honeycomb structures have been widely used as impact protectors in various engineering applications. This paper proposes a data-driven intelligent approach for the prediction of the collision response of honeycomb-reinforced structures under ship collision. In the proposed model, the artificial neural network (ANN) is combined with the dynamic particle swarm optimization (DPSO) algorithm to predict the collision responses of honeycomb reinforced pipe piles, including the maximum collision depth (δmax) and maximum absorption energy (Emax). Furthermore, a data-driven evaluation method, known as grey relational analysis (GRA), is proposed to evaluate the collision responses of the honeycomb-reinforced pipe piles of offshore platforms. Results of the case study demonstrate the accuracy of the DPSO-BP-ANN model, with measured mean-square-error (MSE) of 5.06 × 10−4 and 4.35 × 10−3 and R2 of 0.9906 and 0.9963 for δmax and Emax, respectively. It is shown that the GRA method can provide a comprehensive evaluation of the performance of a honeycomb structure under impact loads. The proposed model provides a robust and efficient assessment tool for the safe design of offshore platforms under ship collisions.

Effects of prenatal exposure to THC on hippocampal neural development in offspring - Hao Peng; Han Li; Yingying Wei; Ruonan Zhang; Xinwen Chang; Lulu Meng; Kai Wang; Qizhi He; Tao Duan (Toxicology Letters, 2023)

A novel ultrasensitive and fast aptamer biosensor of SEB based on AuNPs-assisted metal-enhanced fluorescence - Xueyu Chang; Yaqian Cheng; Xinke Wang; Yonghui Wang; Xueli Liu; Tie Han; Zhixian Gao; Huanying Zhou (Science of The Total Environment, 2023)

Synthesis of gelatin aerogel-containing Al-metal organic framework for the removal of phenolic contaminants from aqueous solutions - Taeyeon Kim; Keunyoung Yun; Nahyun Kim; Byungjun Cha; Jonghun Han; Lewis Kamande Njaramba; S.SD. Elanchezhiyan; Chang Min Park (Journal of Water Process Engineering, 2023)

Greenhouse gas emission indicators, energy consumption efficiency, and optimal carbon emission allowance allocation of the EU countries in 2030 - Tai-Yu Lin; Yung-Ho Chiu; Yi-Nuo Lin; Tzu-Han Chang; Pei-Yu Lin (Gas Science and Engineering, 2023)

Modeling on the phase equilibrium of gas hydrate in electrolytes containing system - Jin Cai; Xiao-Hui Wang; Peng Xiao; Han Tang; Bei Liu; Chang-Yu Sun; Guang-Jin Chen (Fuel, 2023)

Quality relationship between smoked and air-dried bacon of Sichuan-Chongqing in China: Free amino acids, volatile compounds, and microbial diversity - Li Yang; Hongjun Li; Han Wu; Chang Su; Zhifei He (Food Research International, 2023)

Deciphering biochar compost co-application impact on microbial communities mediating carbon and nitrogen transformation across different stages of corn development - Ayodeji Bello; Wanying Liu; Nuo Chang; Kehinde Olajide Erinle; Liting Deng; Ugochi Uzoamaka Egbeagu; Busayo Joshua Babalola; Han Yue; Yu Sun; Zimin Wei; Xiuhong Xu (Environmental Research, 2023)

Asymmetric intramolecular charge transfer enables highly efficient red thermally activated delayed fluorescent emitters - Chao Qu; Huiqin Wang; Yi Man; Zhe Li; Peng Ma; Peng Chang; Xin Li; Chunmiao Han; Yudong Pang; Hui Xu (Chemical Engineering Journal, 2023)

Dual metal-organic frameworks-derived Fe-atomic sites bounded to fine Fe/Fe C nanoparticles for enhanced oxygen electroreduction - Meixin Chen; Fantao Kong; Heliang Yao; Yafeng Chen; Ge Meng; Ziwei Chang; Chang Chen; Han Tian; Lianzhou Wang; Xiangzhi Cui; Jianlin Shi (Chemical Engineering Journal, 2023)

Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival - Zhiwen Jiang; Yijie Zhang; Yanting Wang; Shuo Wang; Jing Chang; Wanshun Liu; Baoqin Han (Carbohydrate Polymers, 2023)

A novel ternary deep eutectic solvent pretreatment for the efficient separation and conversion of high-quality gutta-percha, value-added lignin and monosaccharide from Eucommia ulmoides seed shells - Cong-Jia Duan; Xu Han; Yuan-Hang Chang; Jian Xu; Gan-Lu Yue; Ying Zhang; Yu-Jie Fu (Bioresource Technology, 2023)

Optimizing heterotrophic production of Chlorella sorokiniana SU-9 proteins potentially used as a sustainable protein substitute in aquafeed - Chun-Yen Chen; Jhih-Ci Lu; Yu-Han Chang; Jih-Heng Chen; Dillirani Nagarajan; Duu-Jong Lee; Jo-Shu Chang (Bioresource Technology, 2023)

Anti-Osteoarthritic Effects of Cartilage-Derived Extracellular Matrix in a Rat Osteoarthritis Model - Sang-Hun Lee; Sung-Han Jo; Seon-Hwa Kim; Chang-Su Kim; Sang-Hyug Park (Tissue Engineering and Regenerative Medicine, 2023)

An Efficient Protocol for Agrobacterium-Mediated Transformation and Regeneration of Sugar Beet (Beta vulgaris L.) based on Blade–Petiole Transition Zone Explants - Ziqiang Zhang; Huizhong Zhang; Liang Wang; Bizhou Zhang; Zengjuan Fu; Shangmin Zhao; E Yuanyuan; Wenzhe Zheng; Hui Zhang; Pingan Han; Wenjin Chen; Yue Chang; et al. (Sugar Tech, 2023)

Genome-wide signatures of the geographic expansion and breeding of soybean - Ying-Hui Li; Chao Qin; Li Wang; Chengzhi Jiao; Huilong Hong; Yu Tian; Yanfei Li; Guangnan Xing; Jun Wang; Yongzhe Gu; Xingpeng Gao; Delin Li; et al. (Science China Life Sciences, 2023)

Spatiotemporal Dynamics of the Molecular Expression Pattern and Intercellular Interactions in the Glial Scar Response to Spinal Cord Injury - Leilei Gong; Yun Gu; Xiaoxiao Han; Chengcheng Luan; Chang Liu; Xinghui Wang; Yufeng Sun; Mengru Zheng; Mengya Fang; Shuhai Yang; Lai Xu; Hualin Sun; et al. (Neuroscience Bulletin, 2023)
Nerve regeneration in adult mammalian spinal cord is poor because of the lack of intrinsic regeneration of neurons and extrinsic factors – the glial scar is triggered by injury and inhibits or promotes regeneration. Recent technological advances in spatial transcriptomics (ST) provide a unique opportunity to decipher most genes systematically throughout scar formation, which remains poorly understood. Here, we first constructed the tissue-wide gene expression patterns of mouse spinal cords over the course of scar formation using ST after spinal cord injury from 32 samples. Locally, we profiled gene expression gradients from the leading edge to the core of the scar areas to further understand the scar microenvironment, such as neurotransmitter disorders, activation of the pro-inflammatory response, neurotoxic saturated lipids, angiogenesis, obstructed axon extension, and extracellular structure re-organization. In addition, we described 21 cell transcriptional states during scar formation and delineated the origins, functional diversity, and possible trajectories of subpopulations of fibroblasts, glia, and immune cells. Specifically, we found some regulators in special cell types, such as Thbs1 and Col1a2 in macrophages, CD36 and Postn in fibroblasts, Plxnb2 and Nxpe3 in microglia, Clu in astrocytes, and CD74 in oligodendrocytes. Furthermore, salvianolic acid B, a blood–brain barrier permeation and CD36 inhibitor, was administered after surgery and found to remedy fibrosis. Subsequently, we described the extent of the scar boundary and profiled the bidirectional ligand-receptor interactions at the neighboring cluster boundary, contributing to maintain scar architecture during gliosis and fibrosis, and found that GPR37L1_PSAP, and GPR37_PSAP were the most significant gene-pairs among microglia, fibroblasts, and astrocytes. Last, we quantified the fraction of scar-resident cells and proposed four possible phases of scar formation: macrophage infiltration, proliferation and differentiation of scar-resident cells, scar emergence, and scar stationary. Together, these profiles delineated the spatial heterogeneity of the scar, confirmed the previous concepts about scar architecture, provided some new clues for scar formation, and served as a valuable resource for the treatment of central nervous system injury.

Forest gaps accelerate the degradation of cellulose and lignin in decaying logs in a subalpine forest - Zhuang Wang; Bo Tan; Wanqin Yang; Qin Wang; Chenhui Chang; Lifeng Wang; Han Li; Chengming You; Rui Cao; Yurui Jiang; Jörg Müller (European Journal of Forest Research, 2023)

Crop types and irrigation regimes as drivers of plastisphere bacterial communities in plastic-mulching croplands of subtropical China - Gongwen Luo; Qirui Zhu; Tuo Jin; Jianwei Peng; Ning Zuo; Huiru Zhang; Mengjiao Geng; Ying Huang; Yongliang Han; Chang Tian; Yong Yang; Jiangchi Fei (Applied Soil Ecology, 2023)

Targeted isolation of antitubercular cycloheptapeptides and an unusual pyrroloindoline-containing new analog, asperpyrroindotide A, using LC–MS/MS-based molecular networking - Yi-Qian Han; Qun Zhang; Wei-Feng Xu; Yang Hai; Rong Chao; Cui-Fang Wang; Xue-Mei Hou; Mei-Yan Wei; Yu-Cheng Gu; Chang-Yun Wang; Chang-Lun Shao (Marine Life Science & Technology, 2023)
Further insights on the secondary metabolites of a soft coral-derived fungus Aspergillus versicolor under the guidance of MS/MS-based molecular networking led to the isolation of seven known cycloheptapeptides, namely, asperversiamides A–C ( 1 – 3 ) and asperheptatides A–D ( 4 – 7 ) and an unusual pyrroloindoline-containing new cycloheptapeptide, asperpyrroindotide A ( 8 ). The structure of 8 was elucidated by comprehensive spectroscopic data analysis, and its absolute configuration was determined by advanced Marfey’s method. The semisynthetic transformation of 1 into 8 was successfully achieved and the reaction conditions were optimized. Additionally, a series of new derivatives ( 10 − 19 ) of asperversiamide A ( 1 ) was semi-synthesized and their anti-tubercular activities were evaluated against Mycobacterium tuberculosis H37Ra. The preliminary structure−activity relationships revealed that the serine hydroxy groups and the tryptophan residue are important to the activity.

Editorial: Oceanographic processes linking nearshore, continental shelf, and shelf break - Feng-Hsun Chang; Yun-Chi Lin; Kuo-Ping Chiang; Ya-Han Nien; Chih-hao Hsieh; Wei-Jen Chen; Chin-Chang Hung; Toru Kobari; Hiroaki Saito; William Savidge (Frontiers in Marine Science, 2023)

Investigation of Neuromodulatory Effect of Anodal Cerebellar Transcranial Direct Current Stimulation on the Primary Motor Cortex Using Functional Near-Infrared Spectroscopy - Zeshan Shoaib; Won Kee Chang; Jongseung Lee; Stephanie Hyeyoung Lee; Zephaniah Phillips V; Seung Hyun Lee; Nam-Jong Paik; Han-Jeong Hwang; Won-Seok Kim (The Cerebellum, 2023)

Variation of lead bioaccessibility in soil reference materials: Intra- and inter-laboratory assessments - Xiaoyue Huang; Minghui Chang; Lei Han; Jie Li; Shi-Wei Li; Hong-Bo Li (Chemosphere, 2023)

Growth, health status and gut microbiota of the scalloped spiny lobster (Panulirus homarus) at different salinities - Hu Chen; Junfeng Pan; Yongzhen Wang; Yanbing Qiao; Fenglu Han; Chang Xu; Ardavan Farhadi; Erchao Li (Aquaculture, 2023)

β-catenin facilitates fowl adenovirus serotype 4 replication through enhancing virus-induced autophagy - Ting Wang; Chongyang Wang; Jinjie Han; Xiaolan Hou; Ruochen Hu; Wenchi Chang; Lizhen Wang; Xuefeng Qi; Jingyu Wang (Veterinary Microbiology, 2023)

Triptolide exposure induces oxidative stress and decreases oocyte quality in mouse - Qian-Qian Hao; Zhi-Ran Xu; Han Nie; Feng-Xin Qiao; Ming-Xin Sun; Yue-Cen Liu; Hai-Long Wang; Zhong-Quan Qi; Chang-Long Xu; Yu Liu (Toxicon, 2023)

Carbon capture by macroalgae Sarcodia suae using aquaculture wastewater and solar energy for cooling in subtropical regions - W. Sanjaya Weerakkody; Ka Hin Ling; Hsueh-Han Hsieh; Vicente G. Abedneko; Jeng-Feng Shyu; Tse-Min Lee; Yung-Yen Shih; R.R.M.K.P. Ranatunga; Peter H. Santschi; Chin-Chang Hung (Science of The Total Environment, 2023)

Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson - Ai-Zhu Wang; Hua Han; Qiang-Qiang Fang; Chang-Heng Tan (Phytochemistry, 2023)

Exploration of β-glucosidase-producing microorganisms community structure and key communities driving cellulose degradation during composting of pure corn straw by multi-interaction analysis - Yue Han; Wanying Liu; Nuo Chang; Lei Sun; Ayodeji Bello; Liting Deng; Liyan Zhao; Ugochi Uzoamaka Egbeagu; Bo Wang; Yan Zhao; Mingming Zhao; Ruixin Bi; et al. (Journal of Environmental Management, 2023)

The Cretaceous stationary Lhasa terrane constrained by the paleolatitude of 103 Ma volcanic rocks from the Nima area - Chao Niu; Yiming Ma; Huapei Wang; Tianshui Yang; Haiyan Li; Fei Han; Chang Xu; Junxiang Miao; Zongyong Yang; Hongzhu Cai; Wenpin Gong; Shihong Zhang (Global and Planetary Change, 2023)

Region, vintage, and grape maturity co-shaped the ionomic signatures of the Cabernet Sauvignon wines - Xiao Han; Hao-Cheng Lu; Yu Wang; Xiao-Tong Gao; Hui-Qing Li; Meng-Bo Tian; Ning Shi; Ming-Yu Li; Xiao-Li Yang; Fei He; Chang-Qing Duan; Jun Wang (Food Research International, 2023)

A chemometric study on the identification of 5-methylfurfural and 2-acetylfuran as particular volatile compounds of oxidized fish oil based on SHS-GC-IMS - Yun-Qi Wen; Hong-Wei Zhang; Chang-Hu Xue; Xiao-Han Wang; Shi-Jie Bi; Li-Li Xu; Qian-Qian Xue; Yong Xue; Zhao-Jie Li; Joaquín Velasco; Xiao-Ming Jiang (Food Chemistry, 2023)

Distribution and toxicity of submicron plastic particles in mice - Tsung-Yen Tsou; Sheng-Han Lee; Tzu-Hsuan Kuo; Chu-Chun Chien; Hsin-Chang Chen; Tsun-Jen Cheng (Environmental Toxicology and Pharmacology, 2023)

Analysis on the thermal performance of low-temperature radiant floor coupled with intermittent stratum ventilation (LTR-ISV) for space heating - Xiangfei Kong; Yufan Chang; Man Fan; Han Li (Energy and Buildings, 2023)

ε-Poly( -lysine)-based bioreducible nanogels for mitochondria-targeted delivery and release: Hydrophobicity-tuned nucleus-to-mitochondria organelle-targeting switch and slow disulfide cleavage - Hana Cho; Yeon Su Choi; Da Gyeom Choung; Won Gu Choi; Min Seo Lee; Yong-Yeon Cho; Joo Young Lee; Hye Suk Lee; Han Chang Kang (Chemical Engineering Journal, 2023)

Two-Phase improves Bio-hydrogen and Bio-methane production of anaerobic membrane bioreactor from waste activated sludge with digestate recirculation - Wanjiang Li; Teng Cai; Xueqin Lu; Yule Han; Dilibaierkezi kudisi; Guohua Chang; Ke Dong; Guangyin Zhen (Chemical Engineering Journal, 2023)

Overview of preparation, modification, and application of tunicate-derived nanocellulose - Xiaoyu Lv; Jianing Han; Min Liu; Hui Yu; Kaihua Liu; Yifan Yang; Yi Sun; Panpan Pan; Zhenlin Liang; Lirong Chang; Jingdi Chen (Chemical Engineering Journal, 2023)

Liquid flow behavior in the concentric mesh packing with novel fiber cross-sectional shape in a rotating packed bed - Zhang-Nan Wen; Yan-Bin Li; Han-Zhuo Xu; Ying-Chun Xu; Bao-Chang Sun; Hai-Kui Zou; Guang-Wen Chu (Chemical Engineering Journal, 2023)

Ultrathin metal organic framework nanosheets with rich defects for enhanced fluoride removal - Junyu Su; Maosen Yuan; Lu Han; Hongxia Deng; Jiahao Chang; Yuting Zhuang; Jinyi Wang; Yue Zhang (Chemical Engineering Journal, 2023)

Efficient sunlight promoted nitrogen fixation from air under room temperature and ambient pressure via Ti/Mo composites - Liangchen Chen; Jingxuan Shou; Yutong Chen; Weihang Han; Xuewei Tu; Luping Zhang; Qiang Sun; Jun Cao; Yurong Chang; Hui Zheng (Chemical Engineering Journal, 2023)

Physiological equivalent temperature-based and universal thermal climate index-based adaptive-rational outdoor thermal comfort models - Sheng Zhang; Xia Zhang; Dun Niu; Zhaosong Fang; Han Chang; Zhang Lin (Building and Environment, 2023)

The involvement of AtMKK1 and AtMKK3 in plant-deleterious microbial volatile compounds-induced defense responses - Ching-Han Chang; Wu-Guei Wang; Pei-Yu Su; Yu-Shuo Chen; Tri-Phuong Nguyen; Jian Xu; Masaru Ohme-Takagi; Tetsuro Mimura; Ping-Fu Hou; Hao-Jen Huang (Plant Molecular Biology, 2023)

Responses of seven wetlands carbon sources and sinks to permafrost degradation in Northeast China - Lidong Han; Changcheng Mu; Ning Jiang; Zhongqi Shen; Yihui Chang; Li Hao; Wenhong Peng (Journal of Soils and Sediments, 2023)

Assembling plant diversity mitigates greenhouse gas emissions and achieves high nitrogen removal when treating the low-C/N wastewater by constructed wetlands - Hang Jiang; Yuanyuan Du; Wenjuan Han; Lichunxiao Wang; Chenxu Xiang; Ying Ge; Jie Chang (Environmental Science and Pollution Research, 2023)

A novel stochastic generation method of shale blocks in S-RM considering the particle size effect of morphological features - Chang Liu; Han Zhang; Xinli Hu; Shuangshuang Wu; Xu He; Peng Xia (Bulletin of Engineering Geology and the Environment, 2023)

A symbiosis between Euploea butterflies and yeasts - Wan-Rou Lin; Yi-Ping Chang; Hui-Lin Wu; I-Cheng Hsu; Pi-Han Wang (Symbiosis, 2023)

A mechanism-based understanding of altered drug pharmacokinetics by gut microbiota - Aneela Gulnaz; Ji-Eun Chang; Han-Joo Maeng; Kwang-Hee Shin; Kyeong-Ryoon Lee; Yoon-Jee Chae (Journal of Pharmaceutical Investigation, 2023)

Ecological groups and isotopic niches of earthworms - Gen-Chang Hsu; Katalin Szlavecz; Csaba Csuzdi; Michael Bernard; Chih-Han Chang (Applied Soil Ecology, 2023)

Sensitive electrochemical sensing platform based on Au nanoflower-integrated carbon fiber for detecting interleukin-6 in human serum - Sekar Madhu; Jang Hee Han; Chang Wook Jeong; Jungil Choi (Analytica Chimica Acta, 2023)

Exploration of algal biorefinery frameworks: Optimization, quantification of environmental impacts and economics - Karthickeyan Viswanathan; Jheng-Ming Huang; Tsung-Han Tsai; Jo-Shu Chang; Wei Wu (Algal Research, 2023)

An optimized strategy for inter-satellite links assignments in GNSS - Bingbing Xu; Kai Han; Qianyi Ren; Wenbin Gong; Fengwei Shao; Yukai Wang; Jiachao Chang (Advances in Space Research, 2023)

Analysis of space debris impact source localization based on PVDF piezoelectric film - Enling Tang; Chengrui Xie; Kai Guo; Yafei Han; Chuang Chen; Mengzhou Chang; Liping He (Advances in Space Research, 2023)

Antiviral activity of canine interferon lambda 3 expressed using a recombinant adenovirus against canine coronavirus, canine parvovirus, and canine distemper virus - Dong-Hwi Kim; Sang-Hoon Han; Hyeon-Jeong Go; Da-Yoon Kim; Jae-Hyeong Kim; Joong-Bok Lee; Seung-Yong Park; Chang-Seon Song; Sang-Won Lee; In-Soo Choi (Veterinary Research Communications, 2022)

DLGAP1-AS2 promotes human colorectal cancer progression through trans-activation of Myc - Chunfeng Ren; Hongbin Han; Jingjing Pan; Qian Chang; Wanhai Wang; Xiaobing Guo; Jing Bian (Mammalian Genome, 2022)

Differential bone metabolism and protein expression in mice fed a high-fat diet versus Daurian ground squirrels following natural pre-hibernation fattening - Xuli Gao; Shenyang Shen; Qiaohua Niu; Weilan Miao; Yuting Han; Ziwei Hao; Ning An; Yingyu Yang; Yu Zhang; Han Zhang; Kenneth B. Storey; Hui Chang (Journal of Zhejiang University-SCIENCE B, 2022)

GITRL impairs the immunosuppressive function of MDSCs via PTEN-mediated signaling pathway in experimental Sjögren syndrome - Jie Tian; Beibei Zhang; Qingfang Yuan; Xueqing Sun; Na Peng; Bo Zhu; Chang Liu; Xiaoran Wang; Man Han; Meng Cao; Fan Xiao; Shengjun Wang; et al. (Inflammation Research, 2022)

Morphological classification and molecular marker development of white clover (Trifolium repens L.) parents and hybrids - Seong Seop Han; Hyeon Jin Sun; Chang Ho Eun; Hyo Yeon Lee (Plant Biotechnology Reports, 2022)

Effects of dietary glutathione on the growth performance, skin mucus antioxidant capacity, and immune responses of juvenile taimen Hucho taimen - Chang’an Wang; Shaoxia Lu; Ze Fan; Shicheng Han; Yang Liu; Haibo Jiang; Hongbai Liu (Aquaculture International, 2022)

Decomposition analysis, decoupling status, and future trends of energy consumption in China’s iron and steel industry - Xiaoling Wang; Chang Lu; Baofeng Shi; Yu Chen; Zixuan Han; Jatin Nathwani (Environment, Development and Sustainability, 2022)

Numerical Investigation on Performance Optimization of Offshore Sandwich Blast Walls with Different Honeycomb Cores Subjected to Blast Loading - Hong Lin; Chang Han; Lei Yang; Lin Zhang; Haochen Luan; Pingping Han; Hao Xu; Shuo Zhang (Journal of Marine Science and Engineering, 2022)
As an important protective facility on offshore platform, the blast wall is of great significance in resisting oil and gas explosions. Honeycomb structures are widely used due to their unique deformation and mechanical properties under dynamic impact loads. The aim of this research is to develop an optimized design for an offshore sandwich blast wall with different honeycomb cores. The uniqueness of this paper is providing the quantitative optimization scheme for topological configurations and unit cell geometric parameters of honeycomb structures according to mass consistency and the proposed synthetic evaluation index of anti-blast performance. By using the numerical simulation software ANSYS/LS-DYNA, the CONWEP algorithm was first validated and then adopted to conduct the dynamical performance analysis of the honeycomb blast wall. For comparison purposes, simulating studies on a series of different blast walls were carried out by considering various influential parameters. According to different criteria, the blast resistance of the sandwich honeycomb structures was evaluated. It is found that the sandwich plate with concave arc honeycomb core has the best anti-blast performance compared to that of arrow honeycomb core and concave hexagonal honeycomb core. For the concave arc honeycomb structure, the geometric parameters such as concave angle and aspect ratio of honeycomb unit cell have great influence on the blast-resistance performance. Moreover, the concave arc honeycomb structure with positive gradient arrangement has better anti-blast performance than the negative one. The curved blast wall with the curvature of 1/20 achieves better anti-blast performance than the flat blast wall.

Effects of Dietary Tannic Acid on Growth, Digestion, Immunity and Resistance to Ammonia Stress, and Intestinal Microbial Community in Pacific White Shrimp (Litopenaeus vannamei) - Han Gong; Zhen Qin; Zhao Chen; Jitao Li; Zhiqiang Chang; Jian Li; Ping Chen (Fishes, 2022)
Tannic acid (TA) has great potential as a new feed additive. In this study, we investigated the effects of dietary TA on growth, digestion, nonspecific immunity, and resistance to ammonia stress and intestinal microbiota in Litopenaeus vannamei. The shrimp were fed diets containing different levels of TA: 0 mg/kg (TA-0), 200 mg/kg (TA-200), 400 mg/kg (TA-400), and 800 mg/kg (TA-800) for 56 days, followed by acute ammonia stress for 48 h. The results showed that dietary TA increased the survival rate of the TA-800 group. Dietary TA could improve the morphology of the hepatopancreas and intestinal tissues. After feeding different levels of TA for 56 days, the activities of amylase (AMS) and trypsin (Tryp) were increased, but the activity of lipase (LPS) was decreased. The activities of T-AOC, SOD, and PPO were higher in the hepatopancreas of the three TA treatment groups (p

Numerical Simulation of the Maneuvering Motion Wake of an Underwater Vehicle in Stratified Fluid - Chang Shi; Xide Cheng; Zuyuan Liu; Kunyu Han; Penghui Liu; Long Jiang (Journal of Marine Science and Engineering, 2022)
When a vehicle moves underwater, disturbance is generated and a wake remains that destroys the original free surface and produces a new wake. In order to study the mechanism and characteristics of the wave-making wake generated by the maneuvering motion of an underwater vehicle in density-stratified fluid, the k-ε model and the VOF method that is based on the RANS equation were used in this paper to analyze the SUBOFF model in stratified fluid at different drift angles. Numerical simulation of the maneuvering motion was carried out under these angles, and the corresponding changes in flow field caused by this motion were analyzed. The results from the comparison and analysis of the surface wave wakes under different drift angles in stratified fluid show that with the increasing drift angle, the motion wake of the vehicle still exhibits obvious Kelvin wave system characteristics. However, there are significant changes in hydrodynamic performance. The asymmetry of the surrounding flow field will increase with the increase in the drift angle. The pressure of the underwater vehicle is inversely proportional to the velocity of the surrounding flow field, and the amplitude of the peak and trough of the free surface wave is linearly related to the change in the drift angle. The numerical simulation can serve as a reference for the non-acoustic detection of the motion heading of an underwater vehicle and the motion trajectory of anti-reconnaissance underwater vehicles under actual sea conditions.

Near-surface wind profile test based on accuracy verification of UAV anemometer lifting height in an urban fringe built-up area - Wei Ding; Hong Chen; Han Chang; Yupeng Wang; Dian Zhou; Wei Feng (Environmental Science and Pollution Research, 2022)

Evaluation of the Potential of the Hard Clam (Meretrix meretrix) Shell Which Can Be Used as the Bioindicator for Heavy Metal Accumulation - Yen-Ting Lin; Fang-Chi Chang; Ming-Tsung Chung; Ze-Kai Li; Chang-Chuan Chan; Ying-Sheng Huang; Kuo-Fang Huang; Yu-San Han (Fishes, 2022)
Clams, Meretrix meretrix, were one of the favorite aquatic products in Taiwan and the world. It was reported that the water pollutants such as heavy metals and chemicals might accumulate in the clam body and shell through filter-feeding behavior. Thus, the bivalves could be used as bioindicators in the aquatic environment. The present study analyzed 20 trace elements, Mg, Sr, Li, Cd, Ba, Mn, Al, U, Ti, Pb, Nd, B, S, Zn, Fe, P, Na, K, Cu, and Ni, in the shells of the clams collected from the wild coastal area and cultured ponds to evaluate which elements have the potential to be biomarkers. The concentrations of 20 elements were detected by Solution-Based Inductively Coupled Plasma Mass Spectrometry (SB-ICPMS). Among them, Cd, Al, U, Ti, Nd, S, and K were below the detection limit. The remaining elements were analyzed for accumulation. The levels of Zn, Fe, and Ni possess high variation in an identical environment; so, a PCA was conducted without these three elements to reduce noise. The PCA result proved that the clam could absorb specific trace elements from the habitat. After a period of time, the contents of the absorption in the shells of the clams living in an identical environment became more similar. The analyzed element, Pb, was not found with a special difference in this study. The levels of Na, Sr, Mg, B, Mn, P, Ba, Li, and Cu reflected different sampling sites, which suggested that these elements in the species M. meretrix had the potential to be used as biomarkers for assessing heavy metal accumulation in the environment.

The influence of climate change on the allocation efficiency of new and tradition energy - Kuei-Ying Huang; Yung-ho Chiu; Tzu-Han Chang; Tai-Yu Lin (Environmental Science and Pollution Research, 2022)

Importance of surface charge of soot nanoparticles in determining inhalation toxicity in mice - Ta-Chih Hsiao; Chia-Li Han; Tzu-Ting Yang; Yueh-Lun Lee; Yu-Fang Shen; Yu-Teng Jheng; Chii-Hong Lee; Jer-Hwa Chang; Kian Fan Chung; Han-Pin Kuo; Hsiao-Chi Chuang (Environmental Science and Pollution Research, 2022)

Characterization of Fish Assemblages and Standard Length Distributions among Different Sampling Gears Using an Artificial Neural Network - Tae-Sik Yu; Chang Woo Ji; Young-Seuk Park; Kyeong-Ho Han; Ihn-Sil Kwak (Fishes, 2022)
Several sampling gears are used to collect fish in the lentic ecosystem. The collected fish differ in their characteristics and community structure depending on the sampling gear. The objectives of this study were to 1) compare the community structure of fish assemblages sampled using four sampling gears (kick net, cast net, gill net, and fyke net) in the Singal (SG), Yedang (YD), and Juam (JA) reservoirs, and 2) to understand the characteristics of fishes collected by each sampling gear. A total of 1887 individuals of 14 species, 9113 individuals of 15 species, and 9294 individuals of 27 species were collected, respectively, from the SG, YD, and JA reservoirs. Among the four sampling gears tested, the fyke net collected the largest numbers of species and individuals, while the gill net collections had the highest diversity index. The results obtained with the self-organizing map (SOM) provided a more detailed characterization of the sampled fish than the metrics that are typically used to evaluate sampling gears. In particular, SOM analysis showed a similar pattern of the standard length of fish and sampling gear. Since each sampling gear has unique characteristics, the selection of an appropriate sampling gear should be based on the study objectives and features of the sampling sites.

Seasonal Interaction of River Water-Groundwater-Salt Lake Brine and Its Influence on Water-Salt Balance in the Nalenggele River Catchment in Qaidam Basin, NW China - Jibin Han; Jianxin Xu; Lei Yi; Zheng Chang; Jianping Wang; Haizhou Ma; Baoyun Zhang; Hongchen Jiang (Journal of Earth Science, 2022)

Chestnut caching behavior of Chinese white-bellied rats (Niviventer confucianus) and South China field mice (Apodemus draco): effects of seed size and insect infestation - Xiao-Lei An; Bo Zhang; Tuo Feng; Ning Han; Jing Wang; Xiao-Ning Chen; Ji-Dong Zhao; Ming Qin; Gang Chang; Xiang Hou (Behavioral Ecology and Sociobiology, 2022)

Acute resource pulses from periodical cicadas propagate to belowground food webs but do not affect tree performance - Heikki Setälä; Katalin Szlavecz; Jamie D. Pullen; John D. Parker; Yumei Huang; Chih‐Han Chang (Ecology, 2022)
Acute resource pulses can have dramatic legacies for organismal growth, but the legacy effects of resource pulses on broader aspects of community structure and ecosystem processes are less understood. Mass emergence of periodical cicadas ( Magicicada spp.) provides an excellent opportunity to shed light on the influence of resource pulses on community and ecosystem dynamics: the adults emerge every 13 or 17 years in vast numbers over much of eastern North America, with a smaller but still significant number becoming incorporated into forest food webs. To study the potential effects of such arthropod resource pulse on primary production and belowground food webs, we added adult cicada bodies to the soil surface surrounding sycamore trees and assessed soil carbon and nitrogen concentrations, plant‐available nutrients, abundance and community composition of soil fauna occupying various trophic levels, decomposition rate of plant litter after 50 and 100 days, and tree performance for 4 years. Contrary to previous studies, we did not find significant cicada effects on tree performance despite observing higher plant‐available nutrient levels on cicada addition plots. Cicada addition did change the community composition of soil nematodes and increased the abundance of bacterial‐ and fungal‐feeding nematodes, while plant feeders, omnivores, and predators were not influenced. Altogether, acute resource pulses from decomposing cicadas propagated belowground to soil microbial‐feeding invertebrates and stimulated nutrient mineralization in the soil, but these effects did not transfer up to affect tree performance. We conclude that, despite their influence on soil food web and processes they carry out, even massive resource pulses from arthropods do not necessarily translate to NPP, supporting the view that ephemeral nutrient pulses can be attenuated relatively quickly despite being relatively large in magnitude.

Corrigendum: Sea urchins in acute high temperature and low oxygen environments: The regulatory role of microRNAs in response to environmental stress - Lingshu Han; Yanglei Wu; Pengfei Hao; Beichen Ding; Yuanxin Li; Wenpei Wang; Xianglei Zhang; Chuang Gao; Heng Wang; Luo Wang; Weijie Zhang; Yaqing Chang; et al. (Frontiers in Marine Science, 2022)

Household solid fuel use with diabetes and fasting blood glucose levels among middle-aged and older adults in China - Yuxiong Chen; Siqin Feng; Zhen’ge Chang; Yakun Zhao; Jia Fu; Yijie Liu; Siqi Tang; Yitao Han; Yanbo Liu; Yuanxun Zhang; Shuyang Zhang; Zhongjie Fan (Environmental Science and Pollution Research, 2022)

Identification and QTL mapping of important agronomic traits based on rice short-wide grain CSSL-Z752 with restorer line Xihui 18 as background - Lin-Jun Cai; Han Yun; Xiao-Long Zhong; Dan Du; Xi-Man Peng; Ji-Chao Dai; Zhen-Lin Yang; Fang-Ming Zhao; Chang-Wei Zhang (Cereal Research Communications, 2022)

Site flatfile of Korea meteorological administration’s seismic stations in Korea - Hyung-Ik Cho; Moon-Gyo Lee; Jae-Kwang Ahn; Chang-Guk Sun; Han-Saem Kim (Bulletin of Earthquake Engineering, 2022)

Dynamic Performance and Crashworthiness Assessment of Honeycomb Reinforced Tubular Pipe in the Jacket Platform under Ship Collision - Hong Lin; Chang Han; Lei Yang; Hassan Karampour; Haochen Luan; Pingping Han; Hao Xu; Shuo Zhang (Journal of Marine Science and Engineering, 2022)
The collision between the pipe legs of jacket platforms and bypassing ships is of great concern for the safety assessment of platforms. Honeycomb structures have been widely used owing to their unique deformation and mechanical properties under dynamic impact loads. In this paper, two typical honeycomb structures, namely hexagonal honeycomb and arrow honeycomb, were constructed for the impact protection of inclined pipe legs in jacket platforms, and the present study aimed to assess the dynamical performance and crushing resistance of the designed honeycomb reinforced structure under ship collision by using the numerical simulation software ANSYS/LS-DYNA. The dynamical performance of the honeycomb reinforced pipe leg was investigated considering various influential parameters, including the impact velocity and impact direction. The crashworthiness of the two types of honeycomb was evaluated and compared by different criteria, namely the maximum impact depth (δmax), specific energy absorption (SEA) and the proposed index offset sliding (OS). The results demonstrated that both the hexagonal honeycomb structure and the arrow honeycomb structure can reduce the damage of inclined pipe legs caused by ship collision, while the hexagonal honeycomb can provide the better anti-collision capacity, which can well reduce the offset sliding and better protect the pipe leg from ship collision.

Biomechanical Analysis of Mandibular Implant-Assisted Removable Partial Denture with Distal Extension - Yung-Chung Chen; Chi-Lun Lin; Chen-Han Yu; Hung-Chih Chang; Yang-Ming Lin; Jia-Wei Lin (Journal of Medical and Biological Engineering, 2022)

Inhibition of visfatin alleviates sepsis-induced intestinal damage by inhibiting Hippo signaling pathway - Zhong-Shen Kuang; Yu-Xin Leng; Ning Yang; Zheng-Qian Li; Ya-Nan Zong; Deng-Yang Han; Yue Li; Jin-Dan He; Xing-Ning Mi; Zhu-Kai Cong; Xi Zhu; Chang-Yi Wu; et al. (Inflammation Research, 2022)
Background The aim of this study is to investigate role of Visfatin, one of the pro-inflammatory adipokines, in sepsis-induced intestinal injury and to clarify the potential mechanism. Methods C57BL/6 mice underwent cecal ligation and puncture (CLP) surgery to establish sepsis model in vivo. Intestinal epithelial cells were stimulated with LPS to mimic sepsis-induced intestinal injury in vitro. FK866 (the inhibitor of Visfatin) with or without XMU-MP-1 (the inhibitor of Hippo signaling) was applied for treatment. The expression levels of Visfatin, NF-κB and Hippo signaling pathways-related proteins were detected by western blot or immunohistochemistry. The intestinal cell apoptosis and intestinal injury were investigated by TUNEL staining and H&E staining, respectively. ELISA was used to determine the production of inflammatory cytokines. Results The expression of Visfatin increased in CLP mice. FK866 reduced intestinal pathological injury, inflammatory cytokines production, and intestinal cell apoptosis in sepsis mice. Meanwhile, FK866 affected NF-κB and Hippo signaling pathways. Additionally, the effects of FK866 on inflammatory response, apoptosis, Hippo signaling and NF-κB signaling were partly abolished by XMU-MP-1, the inhibitor of Hippo signaling. In vitro experiments also revealed that FK866 exhibited a protective role against LPS-induced inflammatory response and apoptosis in intestinal cells, as well as regulating NF-κB and Hippo signaling, whereas addition of XMU-MP-1 weakened the protective effects of FK866. Conclusion In short, this study demonstrated that inhibition of Visfatin might alleviate sepsis-induced intestinal injury through Hippo signaling pathway, supporting a further research on Visfatin as a therapeutic target.

Two new 2,5-diketopiperazine derivatives from mangrove-derived endophytic fungus Nigrospora camelliae-sinensis S30 - Dan-Yu Huang; Xu-Hua Nong; Yu-Qin Zhang; Wei Xu; Long-Yu Sun; Tao Zhang; Guang-Ying Chen; Chang-Ri Han (Natural Product Research, 2022)

Revealing Selection in Breeding and Genetic Characteristics of Economically Important Traits of New Species of Apostichopus Japonicas Based on Genome Resequencing and GWAS Analysis - Chao Guo; Yuanxin Li; Jiahui Xie; Lingshu Han; Youquan Wang; Xianglei Zhang; YangLei Wu; Jian Song; Yaqing Chang; Jun Ding (Frontiers in Marine Science, 2022)
Apostichopus japonicas is an economically important species with high nutritional value. However, our knowledge of its genetic diversity and the genetic changes that occurred during its domestication or trait selection is quite limited. In this study, the whole genomes of 254 A . japonicas samples were resequenced. Analyses of the population genetic structure revealed that the genetic diversity of A. japonicas in the north of China is generally high, there was no difference in the population structure among the six cultured populations, and they were divided into two subpopulations together with AY-1 (new species). The results also showed that the genetic diversity of the AY-1 population was relatively low, the degree of linkage of alleles was high, and this population had been subjected to more positive selection. Based on Tajima’s D, F ST analysis, and ROD analysis, the selected intervals and genes of the AY-1 population were identified, with some of the candidate intervals being related to an economically important trait and breeding target, namely, the number of parapodia. Gene Ontology analysis of the candidate genes revealed that the two subpopulations differed in their immune function, protein synthesis, decomposition, and transport, among others. Using GWAS, we identified 39 candidate genes for four economically important traits of A. japonicas , and we verified that those genes contained non-synonymous SNPs. Through this verification, BSL78_00022 and BSL78_00023 were found to be key genes for the number of parapodia in A. japonicas . Of these two genes, BSL78_00022 encodes a protein related to cell differentiation and proliferation, so it was assumed that three non-synonymous substitutions (Ser-Phe, Glu-Asp, and Ala-Val) in this gene are related to the changes in the number of parapodia. Meanwhile, the pleiotropic gene BSL78_04631, which is related to body weight and body wall weight, and promotes protein synthesis and cell growth, has a non-synonymous substitution (IlE-Val), which is assumed to be the reason for the difference in body weight and body wall weight of A. japonicas . These results provide a new perspective for explaining the genetic structure characteristics of A. japonicas and analyzing the selection and economically important traits in the breeding of new species.

Establishment of a set of wheat-rye addition lines with resistance to stem rust - Chang Liu; Jing Wang; Shulan Fu; Long Wang; Hongwei Li; Mian Wang; Yuhong Huang; Qinghua Shi; Yonghong Zhou; Xianrui Guo; Congle Zhu; Jing Zhang; et al. (Theoretical and Applied Genetics, 2022)

Characterization, heterologous expression and engineering of trehalase for biotechnological applications - Han Gao; Jin-Song Gong; Chang Su; Heng Li; Zheng-Hong Xu; Jin-Song Shi (Systems Microbiology and Biomanufacturing, 2022)

Salt sealing induced in situ N-doped porous carbon derived from wheat bran for the removal of doxycycline from aqueous solution - Linlin Liang; Xinyong Niu; Xiuli Han; Chun Chang; Junying Chen (Environmental Science and Pollution Research, 2022)

Species identity but not richness affects effluent nitrogen, phosphorus, and potassium concentrations and the ratios in floating-constructed wetlands - Wenjuan Han; Yuanyuan Du; Chenxu Xiang; Yu Liu; Jie Chang; Ying Ge (Environmental Science and Pollution Research, 2022)

The combined effects of telmisartan and ramipril on hypertension and cardiovascular injury - Do-Hyung Lee; Min-Tae Kim; Hyung-Won Lee; Joo-Hui Han; Chang-Seon Myung (Journal of Pharmaceutical Investigation, 2022)

Sea Urchins in Acute High Temperature and Low Oxygen Environments: The Regulatory Role of microRNAs in Response to Environmental Stress - Lingshu Han; Yanglei Wu; Pengfei Hao; Beichen Ding; Yuanxin Li; Wenpei Wang; Xianglei Zhang; Chuang Gao; Heng Wang; Luo Wang; Weijie Zhang; Yaqing Chang; et al. (Frontiers in Marine Science, 2022)
Strongylocentrotus intermedius is an economically valuable sea urchin species in China. However, its growth and survival are severely constrained by ocean warming and the hypoxia that often accompanies high water temperatures. MicroRNAs (miRNAs) are important regulators of gene expression in response to environmental change. In this study, high-throughput RNA sequencing was used to investigate changes in miRNA expression in S. intermedius under heat (25°C), hypoxia (2 mg/L O 2 ), and combined heat and hypoxia stresses. Twelve small RNAs libraries were constructed and 17, 14, and 23 differentially expressed miRNAs (DEMs) were identified in the heat, hypoxia, and combined stress groups ( P <0.05), respectively. Gene ontology and Kyoto Encyclopedia of Genes and Genomes pathway functional analyses of putative target genes of the DEMs suggested that these miRNAs were important in basal metabolism, apoptosis, oxidative stress, and immune-related pathways. By co-analysis with published transcriptome data, key DEMs (miR-193, miR-184, miR-133, miR-125, miR-2008) and their key target genes ( EGF3 , ABCB4 , CYCL , PAN2 , CALN ) were identified. Quantitative real-time PCR analysis of the expression of 10 DEMs and their key target genes confirmed the RNA sequencing results. These results provide information on gene expression regulation of the molecular mechanisms underlying the response of S. intermedius to multi-cause environmental stresses.

Influence of Block form on the Shear Behaviour of Soft Soil–Rock Mixtures by 3D Block Modelling Approaches - Han Zhang; Daniela Boldini; Lehua Wang; Huafeng Deng; Chang Liu (Rock Mechanics and Rock Engineering, 2022)
The influence of block forms on the shear behaviour of soil–rock mixtures with soft blocks (soft S–RMs) can be efficiently investigated by the discrete element method (DEM) on the basis of accurate 3D models accounting for the block breakage. This paper proposes a novel modelling approach, based on the spherical harmonics series, for the generation of 3D block geometries with different forms but same convexity and angularity. An already existing non-overlapping modelling approach was improved, characterized by a reduced computational cost, for the set-up of 3D block DEM models accounting for the block breakage. A number of soft S–RM DEM samples, subjected to numerical direct shear tests, were generated to analyze the influence of block forms and volumetric block proportion VBP on the mesoscopic and macroscopic behaviours. The results showed that the breakage degree is maximum for the spheroidal blocks, followed by the oblate, prolate and blade ones, due to the combined influence of the block frictional sliding and rotation. The shear strength of soft S–RMs is mainly controlled by the block interlocking and breakage, being maximum in the case of spheroidal block samples when the applied normal stress is low and in the case of prolate and blade ones for a high normal stress. It was found that a nonlinear Mohr–Coulomb criterion can provide a good description of the shear strength envelope of soft S–RMs. Soft S–RMs are characterized by a higher friction angle if composed by spheroidal and prolate blocks when the VBP is 40%, due to their elevated block interlocking, and in the case of prolate and blade blocks when the VBP is 60% at the higher normal stress, due to their lower block breakage degree.

Energy performance of European countries by considering the role of forest - Liang Chun Lu; Shih-Yung Chiu; Yung-Ho Chiu; Tzu-Han Chang; William Tang (Environmental Science and Pollution Research, 2022)

Society organization, not pathogenic viruses, is the fundamental cause of pandemics - Qianqian Wang; Jie Han; Hong Chang; Chaoqi Wang; Eric Lichtfouse (Environmental Chemistry Letters, 2022)

Comparative analysis of genome-based CAZyme cassette in Antarctic Microbacterium sp. PAMC28756 with 31 other Microbacterium species - Sushma Gupta; So-Ra Han; Byeollee Kim; Chang-Muk Lee; Tae-Jin Oh (Genes & Genomics, 2022)

Prognostic significance of three endothelial nitric oxide synthase (eNOS) polymorphisms and metabolic syndrome (MetS) in patients with colorectal cancer - Eun Ju Ko; Eo Jin Kim; Hye Jung Cho; Jisu Oh; Han Sung Park; Chang Soo Ryu; Jung Oh Kim; Hak Hoon Jun; So Young Chong; Jong Woo Kim; Nam Keun Kim (Genes & Genomics, 2022)

Relationships of multiple metals exposure, global DNA methylation, and urothelial carcinoma in central Taiwan - Hui-Tsung Hsu; Hui-Ling Lee; Hsu-Hui Cheng; Chao-Hsiang Chang; Chiu-Shong Liu; Po-Jen Hsiao; Han Chang; Chi-Shun Lien; Mu-Chi Chung; Chi-Jung Chung (Archives of Toxicology, 2022)

Integrinβ3 mediates the protective effects of soluble receptor for advanced glycation end-products during myocardial ischemia/reperfusion through AKT/STAT3 signaling pathway - Xuejie Han; Xinying Guo; Jing Chang; Jie Zhang; Lu Chen; Hongxia Wang; Fenghe Du; Xiangjun Zeng; Caixia Guo (Apoptosis, 2022)

Globally, tree fecundity exceeds productivity gradients - Valentin Journé; Robert Andrus; Marie‐Claire Aravena; Davide Ascoli; Roberta Berretti; Daniel Berveiller; Michal Bogdziewicz; Thomas Boivin; Raul Bonal; Thomas Caignard; Rafael Calama; Jesús Julio Camarero; et al. (Ecology Letters, 2022)
Lack of tree fecundity data across climatic gradients precludes the analysis of how seed supply contributes to global variation in forest regeneration and biotic interactions responsible for biodiversity. A global synthesis of raw seedproduction data shows a 250‐fold increase in seed abundance from cold‐dry to warm‐wet climates, driven primarily by a 100‐fold increase in seed production for a given tree size. The modest (threefold) increase in forest productivity across the same climate gradient cannot explain the magnitudes of these trends. The increase in seeds per tree can arise from adaptive evolution driven by intense species interactions or from the direct effects of a warm, moist climate on tree fecundity. Either way, the massive differences in seed supply ramify through food webs potentially explaining a disproportionate role for species interactions in the wet tropics.

Organic Carbon Oxidation in the Sediment of the Ulleung Basin in the East Sea - Jae Seong Lee; Sung-Han Kim; Ju-Wook Baek; Kyung-Tae Kim; Dongseon Kim; Young-il Kim; Won-Chan Lee; Sung-Uk An; Chang Hwan Kim; Chan Hong Park; Sokjin Hong (Journal of Marine Science and Engineering, 2022)
We characterized the biogeochemical organic carbon (Corg) cycles in the surface sediment layer of the Ulleung Basin (UB) of the East Sea. The total oxygen uptake (TOU) rate and the diffusive oxygen uptake (DOU) rate of the sediment were measured using an autonomous in situ benthic lander equipped with a benthic chamber (KIOST BelcII) and a microprofiler (KIOST BelpII). The TOU rate was in the range of 1.51 to 1.93 mmol O2 m−2 d−1, about double the DOU rate. The high TOU/DOU ratio implies that the benthic biological activity in the upper sediment layer is one of the important factors controlling benthic remineralization. The in situ oxygen exposure time was about 20 days, which is comparable to the values of other continental margin sediments. The sedimentary Corg oxidation rates ranged from 6.4 to 6.5 g C m−2 yr−1, which accounted for ~2% of the primary production in UB. The Corg burial fluxes ranged from 3.14 ± 0.12 to 3.48 ± 0.60 g C m−2 yr−1, corresponding to more than 30% of the deposited Corg buried into the inactive sediment deep layer.

One new piperazinedione isolated from a mangrove-derived fungus Aspergillus niger JX-5 - Meng Bai; Yue Wang; Ting Liu; Yu-Xing Lian; Qi-Qi Bai; Xiao-Ping Song; Chang-Ri Han; Cai-Juan Zheng; Guang-Ying Chen (Natural Product Research, 2022)

Combination analysis of single-molecule long-read and Illumina sequencing provides insights into the anthocyanin accumulation mechanism in an ornamental grass, Pennisetum setaceum cv. Rubrum - Lingyun Liu; Ke Teng; Xifeng Fan; Chao Han; Hui Zhang; Juying Wu; Zhihui Chang (Plant Molecular Biology, 2022)

The active ingredient (DSH-20) of Salvia miltiorrhiza flower reduces oxidative damage and apoptosis in cardiomyocytes by regulating miR-1 - Panxia Cao; Yanpin Xue; Mengjiao Guo; Xue Jiang; Zhen Lei; Shuibo Gao; Xinzhou Wang; Haixia Gao; Yongjun Han; Hongbo Chang; Shanshan Liu; Liping Dai; et al. (Molecular Biology Reports, 2022)

Bioremediation of decabromodiphenyl ether or benzo(a)pyrene-contaminated rice-paddy soil - Han-Hsin Li; Shu-Chi Chang (Journal of Soils and Sediments, 2022)

Do Forests help environmental development of Cities in China? - Liang Chun Lu; Yung-ho Chiu; Shih-Yung Chiu; Tzu-Han Chang (Environment, Development and Sustainability, 2022)

Comparative Lipidome and Transcriptome Provide Novel Insight Into Polyunsaturated Fatty Acids Metabolism of the Sea Urchin - Heng Wang; Wenfei Zhao; Xiaoyu Liu; Debao Gang; Rantao Zuo; Lingshu Han; Yaqing Chang; Jun Ding (Frontiers in Marine Science, 2022)
The sea urchin Strongylocentrotus intermedius is one of the most economically important echinoids harvested from northeast Pacific Ocean coastal waters. The gonads of sea urchins have high nutritional value and are primarily a candidate source of polyunsaturated fatty acids (PUFA). PUFAs are essential for human health, and the biological synthesis and industry production of PUFA have attracted more and more attention from the scientific community. Moreover, PUFAs are important necessary nutrients that determine not only the nutritional value of sea urchins but guarantee their normal growth and reproduction. In this study, we divided 178 sea urchins into three groups (high, medium, and low concentration PUFA groups) according to the concentration of PUFAs, and conducted integrative lipidomics and transcriptomics analyses of different PUFA abundances of S. intermedius to determine the critical genes related to PUFA metabolism in sea urchin gonads. Illumina sequencing generated 894,295,712 clean reads (133.28 Gb) in 18 cDNA libraries. Among all of the unigenes, nine up- and seven down-regulated unigenes were found in a comparison of the “high vs low” concentration PUFA groups of gonads. Interestingly, we found that tudor domain-containing protein 3 (TDRD3) was up-regulated in the high concentration PUFA group, and this gene was significantly related to eicosapentaenoic acid (EPA) in the correlation analysis (p<0.05), and may be used as a candidate marker for EPA biosynthesis and metabolism in the sea urchin. The lipidome and transcriptome information will provide a basic resource for further studies designed to elucidate the molecular mechanism of PUFA metabolism in marine invertebrates, and act as a valuable resource for the practical applications and regulation of the sea urchin aquaculture industry in the future.

Hypothermal Effects on Energy Supply for Ionocytes in Gills of Freshwater- and Seawater-Acclimated Milkfish, Chanos chanos - Chia-Hao Chang; Chia-Jui Liu; Wei-Jie Lu; Li-Yang Wu; Kuang-Jie Lai; Yu-Ting Lin; Tsung-Han Lee (Frontiers in Marine Science, 2022)
The milkfish, Chanos chanos , is an important aquaculture species that can be cultured in freshwater (FW) and seawater (SW) ponds because of its high euryhalinity. In winter, cold snap leading to high mortality of this tropical species is a critical issue for the aquaculture industry in Taiwan. Under hypothermal stress, however, changes in energy supply for osmoregulation of this euryhaline species is intriguing. In this study, we used an antibody against glycogen phosphorylase (GP) to identify glycogen-rich (GR) cells distributed adjacent to the mitochondria-rich (MR) ionocytes in milkfish gills. Glucose transporter 1 (GLUT1), which plays a major role in energy supply, was also identified and localized in GR cells. Moreover, the expression of indicators of aerobic metabolism and energy production, citrate synthase (CS) and cytochrome c oxidase (COX), were analyzed in gills of FW- and SW-acclimated milkfish to reveal different strategies of energy utilization under hypothermal stress. When exposed to a low-temperature environment, SW individuals used branchial glycogen and lactate to match the energy demands of aerobic metabolism in ionocytes, and elevated aerobic capacity to support and maintain normal functions in gills. However, branchial glycogen mainly localized in the GR cells of FW milkfish was not utilized under hypothermal stress. Meanwhile, a similar level of branchial COX activity and COXIV protein abundance at low temperatures between FW and SW milkfish indicated similar energy requirements in gills. This suggested that another source, but not branchial glycogen, maintained the energy demand in FW milkfish. The present study illustrated differential energy supply strategies in gills between SW- and FW-acclimated milkfish for osmoregulation under low temperatures.

Curcumin Inhibits Cell Damage and Apoptosis Caused by Thapsigargin-Induced Endoplasmic Reticulum Stress Involving the Recovery of Mitochondrial Function Mediated by Mitofusin-2 - He-Yan Zhou; Yu-Ying Sun; Ping Chang; Han-Chang Huang (Neurotoxicity Research, 2022)

Targeting GATA1 and p2x7r Locus Binding in Spinal Astrocytes Suppresses Chronic Visceral Pain by Promoting DNA Demethylation - Yan-Yan Wu; Hai-Long Zhang; Xiaomin Lu; Han Du; Yong-Chang Li; Ping-An Zhang; Guang-Yin Xu (Neuroscience Bulletin, 2022)
Irritable bowel syndrome is a gastrointestinal disorder of unknown etiology characterized by widespread, chronic abdominal pain associated with altered bowel movements. Increasing amounts of evidence indicate that injury and inflammation during the neonatal period have long-term effects on tissue structure and function in the adult that may predispose to gastrointestinal diseases. In this study we aimed to investigate how the epigenetic regulation of DNA demethylation of the p2x7r locus guided by the transcription factor GATA binding protein 1 (GATA1) in spinal astrocytes affects chronic visceral pain in adult rats with neonatal colonic inflammation (NCI). The spinal GATA1 targeting to DNA demethylation of p2x7r locus in these rats was assessed by assessing GATA1 function with luciferase assay, chromatin immunoprecipitation, patch clamp, and interference in vitro and in vivo . In addition, a decoy oligodeoxynucleotide was designed and applied to determine the influence of GATA1 on the DNA methylation of a p2x7r CpG island. We showed that NCI caused the induction of GATA1, Ten-eleven translocation 3 (TET3), and purinergic receptors (P2X7Rs) in astrocytes of the spinal dorsal horn, and demonstrated that inhibiting these molecules markedly increased the pain threshold, inhibited the activation of astrocytes, and decreased the spinal sEPSC frequency. NCI also markedly demethylated the p2x7r locus in a manner dependent on the enhancement of both a GATA1–TET3 physical interaction and GATA1 binding at the p2x7r promoter. Importantly, we showed that demethylation of the p2x7r locus (and the attendant increase in P2X7R expression) was reversed upon knockdown of GATA1 or TET3 expression, and demonstrated that a decoy oligodeoxynucleotide that selectively blocked the GATA1 binding site increased the methylation of a CpG island in the p2x7r promoter. These results demonstrate that chronic visceral pain is mediated synergistically by GATA1 and TET3 via a DNA-demethylation mechanism that controls p2x7r transcription in spinal dorsal horn astrocytes, and provide a potential therapeutic strategy by targeting GATA1 and p2x7r locus binding.

Hydrochloric acid-treated Bacillus subtilis ghosts induce IL-1 beta, IL-6, and TNF-alpha in murine macrophage - Young-Min Kim; Kwang-Su Lee; Won-Mun Kim; Min Kim; Han-Oh Park; Chang Won Choi; Joong-Soo Han; Shin-Young Park; Ki-Sung Lee (Molecular & Cellular Toxicology, 2022)
Background Bacterial ghosts (BGs) are empty cell envelopes commonly generated using Gram-negative bacteria; they represent a potential platform for efficient adjuvant and vaccine delivery systems. However, the efficient production of BGs from bacteria in a short period of time is challenging. Objective The purpose of this study was to investigate the possibility of producing BGs in the Gram-positive Bacillus subtilis using various chemicals, and the potential application of BGs as a novel immunomodulatory agent. Results In this study, Bacillus subtilis ghosts (BSGs) were generated, for the first time to the best of our knowledge, using the minimum inhibitory concentration (MIC) of hydrochloric acid (HCl; 6.25 mg/mL), sulfuric acid (H 2 SO 4 ; 3.125 mg/mL), and nitric acid (HNO 3 ; 6.25 mg/mL). Among the BSGs generated using these chemicals, HCl-induced BSGs were completely DNA-free as confirmed by real-time polymerase chain reaction. Scanning electron microscopy showed the formation of transmembrane lysis tunnel structures in HCl-induced BSGs. Murine macrophages exposed to the HCl-induced BSGs at a concentration of 1 × 10 5 CFU/mL showed a cell viability of 97.8%. Additionally, HCl-induced BSGs upregulated the expression of pro-inflammatory cytokines including interleukin (IL)-1β, tumor necrosis factor alpha, and IL-6. Furthermore, we found differences in the protein expression profiles between intact live bacteria and BSGs using two-dimensional electrophoresis coupled with peptide mass fingerprinting/matrix-assisted laser desorption/ionization-time of flight mass spectrometry analysis. Conclusion These data suggest that the HCl-induced BSGs may be potentially safe and effective candidates for inactivated bacterial vaccines and/or immunostimulants.

Analysis of genotype–phenotype relationships in 90 Chinese probands with Waardenburg syndrome - Guojian Wang; Xiaohong Li; Xue Gao; Yu Su; Mingyu Han; Bo Gao; Chang Guo; Dongyang Kang; Shasha Huang; Yongyi Yuan; Pu Dai (Human Genetics, 2022)

Fault reactivation with rapid slip along subsidiary faults in the Yangsan Fault zone, SE Korea - Chang-Min Kim; Youngbeom Cheon; Raehee Han; Gi Young Jeong; Jong Ok Jeong (Geosciences Journal, 2022)

The significance of riparian communities in the energy flow of subtropical stream ecosystems - Yi-Chang Liao; An-Cheng Lin; Han-Ni Tsai; Yu-Ting Yen; Chyng-Shyan Tzeng; Man-Miao Yang; Hsing-Juh Lin (Aquatic Sciences, 2022)

A new isoflavone from the fruits of Ficus auriculata and its antibacterial activity - Tai-Ming Shao; Hai-Xia Liao; Xiao-Bao Li; Guang-Ying Chen; Xiao-Ping Song; Chang-Ri Han (Natural Product Research, 2022)

The biogeographical history of giant earthworms of the Metaphire formosae species group (Clitellata: Megascolecidae) in Taiwan and the Ryukyu Archipelago, with the description of a new species from Yonagunijima, Southern Ryukyus - Huei-Ping Shen; Chih-Han Chang; Hidetoshi Ota (Organisms Diversity & Evolution, 2022)

Groundwater contamination source identification using improved differential evolution Markov chain algorithm - Yukun Bai; Wenxi Lu; Jiuhui Li; Zhengbo Chang; Han Wang (Environmental Science and Pollution Research, 2022)

Prospects and challenges of epigenomics in crop improvement - Yuhong Huang; Yang Liu; Chang Liu; James A. Birchler; Fangpu Han (Genes & Genomics, 2022)

Bacteria-based nanosystems for enhanced antitumor therapy - Yu Han; Miao Fan; Dandan Han; Kun Ge; Jin Chang; Jinchao Zhang (Science China Life Sciences, 2022)

Transcriptomic and Metabolomic Analyses Provide Insights into the Growth and Development Advantages of Triploid Apostichopus japonicus - Jiahui Xie; Yi Sun; Yue Cao; Lingshu Han; Yuanxin Li; Beichen Ding; Chuang Gao; Pengfei Hao; Xin Jin; Yaqing Chang; Jian Song; Donghong Yin; et al. (Marine Biotechnology, 2022)
Polyploid breeding is widely used in aquaculture as an important area of new research. We have previously grown Apostichopus japonicus triploids with a growth advantage. The body length, body weight, and aestivation time of triploid and diploid A. japonicus were measured in this study, and the transcriptome and metabolome were used to examine the growth advantage of triploids A. japonicus . The results showed that the proportion of triploid A. japonicus with a body length of 6–12 cm and 12–18 cm was significantly higher than that of diploid A. japonicus , and triploid A. japonicus had a shorter aestivation time (39 days) than diploid (63 days). We discovered 3296 differentially expressed genes (DEGs); 13 DEGs (for example, cyclin-dependent kinase 2 ) related to growth advantage, immune regulation, and energy storage were screened as potential candidates. According to Gene Ontology (GO) enrichment analysis, DEGs were significantly enriched in the cytoplasm (cellular component), ATP binding process (molecular function), oxidation–reduction process (biological process), and other pathways. According to the Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment data, DEGs were significantly enriched in ribosome production and other areas. We discovered 414 significant differential metabolites (SDMs), with 11 important SDMs (for example, nocodazole) linked to a growth advantage. SDMs are significantly enriched in metabolic pathways, as well as other pathways, according to the KEGG enrichment results. According to a combined transcriptome and metabolome analysis, 6 DEGs have regulatory relationships with 11 SDMs, which act on 11 metabolic pathways together. Our results further enrich the biological data of triploid A. japonicus and provide useful resources for genetic improvement of this species.

Mortality outcomes and survival patterns of patients with myeloproliferative neoplasms in Malaysia - Yee Yee Yap; Jameela Sathar; Kian Boon Law; Sen Mui Tan; Ngee Siang Lau; Tee Chuan Ong; Ai Sim Goh; Teng Keat Chew; Soo Min Lim; See Guan Toh; Xavier Yoon Han Sim; Padmini Menon; et al. (Cancer Causes & Control, 2022)

Petrogenesis of the Late Triassic Mengsong strongly peraluminous granites in the southeastern Tibetan Plateau: highly fractionated from crystal mush - Feng Cong; Fu-Yuan Wu; Wen-Chang Li; De-Feng He; Zai-Bo Sun; Xiao-Ming Huang; Zhi-Zhong Hu; Han Zhao (International Geology Review, 2022)

A new N -containing phenolic glycoside from Capsicum annuum L. - Changwei Song; Changyan Yu; Xinting Zhu; Xirong Luo; Yong Zhang; Lingjie Meng; Yong Luo; Han Chang; Cheng Qin; Yun Liu (Natural Product Research, 2022)

Subjective visual vertical imprecision during lateral head tilt in patients with chronic dizziness - Ariel A. Winnick; Chia-Han Wang; Yu-Hung Ko; Tzu-Pu Chang (Experimental Brain Research, 2022)

Antibiotic resistance genes on the Qinghai-Tibet Plateau above an elevation of 5,000 m - Xiaomin Wang; Chang Han; Bangrui Lan; Cheng Wang; Guibing Zhu (Environmental Science and Pollution Research, 2022)

Geochemical characteristics and origin of Chang-9 crude oil of Triassic Yanchang Formation in Zhidan area, Ordos Basin, China - Zhengyu Wu; Shijia Chen; Chengshan Li; Jian Yu; Yibo Chang; Zixing Lu; Xin He; Haifeng Zhang; Han Meimei (Arabian Journal of Geosciences, 2022)

A preliminary study of natural environmental change and its impact on early Late Paleolithic people in the northeast central Korean Peninsula during Marine Istope Stage 3 (40–30k cal a bp ) - Sangheon Yi; Chang‐Gyun Han; Keun‐Chang Oh; In Sun Seo; Dongwook Kim; Jaeyoung Lee; Min Han; Hanwoo Choi; Jaesoo Lim; Sujeong Park; Chang‐Pyo Jun; Taesop Cho (Journal of Quaternary Science, 2022)
We comprehensively analyzed sediments obtained from an archeological excavation. A trench sediment profile of Maedun Cave (MC), South Korea, was analyzed geoarchaeologically. Multi‐proxy analyses (palynomorphs, grain size, magnetic susceptibility, animal bones and artifacts) reflected the vegetation, hydroclimate and lives of prehistoric people at Marine Isotope Stage (MIS) 3 (ca. 40–30k cal a bp ) in the early Late Paleolithic. The palynoflora consisted of pollen and non‐pollen palynomorphs. Under the air‐circulation system in the cave, anemophilous pollen flowed in during the day, whereas waterborne pollen and spores, and freshwater algae, were transported by flooding during the summer monsoon rainy season. Mixed conifer and deciduous broad‐leaved forest with an understory of pteridophytes flourished around the north‐east central Korean Peninsula during MIS 3. Freshwater algae and grass pollen records may reflect precipitation intensity. It is assumed that they had flowed in during flooding caused by high precipitation during the enhanced East Asian summer monsoon, corresponding to Dansgaard–Oeschger (D/O) events 5 and 8 of δ 18 O GISP2 and Hulu Cave. The prehistoric people hunted herbivorous animals in the area around MC and sheltered inside it seasonally. They also used the grains of oats growing near the dwelling as a source of food.

Six-DOF CFD Simulations of Underwater Vehicle Operating Underwater Turning Maneuvers - Kunyu Han; Xide Cheng; Zuyuan Liu; Chenran Huang; Haichao Chang; Jianxi Yao; Kangli Tan (Journal of Marine Science and Engineering, 2021)
Maneuverability, which is closely related to operational performance and safety, is one of the important hydrodynamic properties of an underwater vehicle (UV), and its accurate prediction is essential for preliminary design. The purpose of this study is to analyze the turning ability of a UV while rising or submerging; the computational fluid dynamics (CFD) method was used to numerically predict the six-DOF self-propelled maneuvers of submarine model BB2, including steady turning maneuvers and space spiral maneuvers. In this study, the overset mesh method was used to deal with multi-body motion, the body force method was used to describe the thrust distribution of the propeller at the model scale, and the numerical prediction also included the dynamic deflection of the control planes, where the command was issued by the autopilot. Then, this study used the published model test results of the tank to verify the effectiveness of the CFD prediction of steady turning maneuvers, and the prediction of space spiral maneuvers was carried out on this basis. The numerical results show that the turning motion has a great influence on the depth and pitch attitude of the submarine, and a “stern heavier” phenomenon occurs to a submarine after steering. The underwater turning of a submarine can not only reduce the speed to brake but also limit the dangerous depth. The conclusion is of certain reference significance for submarine emergency maneuvers.

MdKCS2 increased plant drought resistance by regulating wax biosynthesis - Xin-Yu Lian; Huai-Na Gao; Han Jiang; Chang Liu; Yuan-Yuan Li (Plant Cell Reports, 2021)

Short-term effects of exposure to particulate matter and air pollution on hospital admissions for asthma and chronic obstructive pulmonary disease in Gyeonggi-do, South Korea, 2007–2018 - Chang Hoon Han; Haeyong Pak; Jae Ho Chung (Journal of Environmental Health Science and Engineering, 2021)

Association between ozone exposure and prevalence of mumps: a time-series study in a Megacity of Southwest China - Wenjun Xie; Han Zhao; Chang Shu; Bin Wang; Wen Zeng; Yu Zhan (Environmental Science and Pollution Research, 2021)

Comparing the effects of plant diversity on the nitrogen removal and stability in floating and sand-based constructed wetlands under ammonium/nitrate ratio disturbance - Yuanyuan Du; Shaodan Niu; Hang Jiang; Bin Luo; Qian Wang; Wenjuan Han; Yu Liu; Jie Chang; Ying Ge (Environmental Science and Pollution Research, 2021)

Turnover Time of the East Sea (Sea of Japan) Meridional Overturning Circulation - MyeongHee Han; Yeon S. Chang; Hyoun-Woo Kang; Dong-Jin Kang; Yong Sun Kim (Frontiers in Marine Science, 2021)
The East Sea (ES; Sea of Japan) meridional overturning circulation (MOC) serves as a crucial mechanism for the transportation of dissolved, colloidal, and suspended particulate matters, including pollutants, on the surface to deep waters via thermohaline circulation. Therefore, understanding the structure of the ES MOC is critical for characterizing its temporal and spatial distribution. Numerous studies have estimated these parameters indirectly using chemical tracers, severely limiting the accuracy of the results. In this study, we provide a method for directly estimating the turnover times of the ES MOC using the stream functions calculated from HYbrid Coordinate Ocean Model (HYCOM) reanalysis data by averaging the flow pattern in the meridional 2-D plane. Because the flow pattern is not consistent but various over time, three cases of stream function fields were computed over a 20-year period. The turnover time was estimated by calculating the time required for water particles to circulate along the streamlines. In the cases of multiple (two or three) convection cells, we considered all possible scenarios of the exchange of water particles between adjacent cells, so that they circulated over those cells until finally returning to the original position and completing the journey on the ES MOC. Three different cell cases were tested, and each case had different water particle exchange scenarios. The resulting turnover times were 17.91–58.59 years, 26.41–37.28 years, and 8.68–45.44 years for the mean, deep, and shallow convection cases, respectively. The maximum turnover time, namely 58.59 years, was obtained when circulating the water particle over all three cells, and it was approximately half of that estimated by the chemical tracers in previous studies (∼100 years). This underestimation arose because the streamlines and water particle movement were not calculated in the shallow (<300 m) and deep areas (>3,000 m) in this study. Regardless, the results of this study provide insight into the ES MOC dynamics and indicate that the traditional chemical turnover time represents only one of the various turnover scenarios that could exist in the ES.

Red light enhances folate accumulation in wheat seedlings - Jianwei Chang; Chong Xie; Pei Wang; Zhenxin Gu; Yongbin Han; Runqiang Yang (Journal of Zhejiang University-SCIENCE B, 2021)

Methacrylic functionalized hybrid carbon nanomaterial for the selective adsorption and detection of progesterone in wastewater - Xia Cui; Hua Shu; Lu Wang; Guoning Chen; Jili Han; Qianqian Hu; Kamran Bashir; Zhimin Luo; Chun Chang; Jia Zhang; Qiang Fu (Environmental Science and Pollution Research, 2021)

The second wave of earthworm invasions in North America: biology, environmental impacts, management and control of invasive jumping worms - Chih-Han Chang; Marie L. C. Bartz; George Brown; Mac A. Callaham; Erin K. Cameron; Andrea Dávalos; Annise Dobson; Josef H. Görres; Bradley M. Herrick; Hiroshi Ikeda; Samuel W. James; Marie R. Johnston; et al. (Biological Invasions, 2021)

Mutation of the sixth amino acid of the Rep protein has no effect on porcine circovirus 2b but enhances porcine circovirus 2d replication in vitro - Xiaoyan Wu; Shuo Wang; Changxun Xin; Chen Li; Jianli Shi; Zhe Peng; Chang Liu; Hong Han; Ying Yang; Yao Tian; Jiaxin Li; Shaojian Xu; et al. (Archives of Virology, 2021)

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Impacts of pH on the Fitness and Immune System of Pacific White Shrimp - Veran Weerathunga; Wei-Jen Huang; Sam Dupont; Hsueh-Han Hsieh; Nathangi Piyawardhana; Fei-Ling Yuan; Jhe-Syuan Liao; Chia-Yu Lai; Wei-Ming Chen; Chin-Chang Hung (Frontiers in Marine Science, 2021)
The atmospheric partial pressure of CO 2 ( p CO 2 ) has been increasing dramatically since the beginning of the industrial revolution and about 30% of the CO 2 produced by anthropogenic activities was absorbed by the ocean. This led to a perturbation of the seawater carbonate chemistry resulting in a decrease of the average surface ocean pH by 0.1 and termed ocean acidification (OA). Projections suggest that p CO 2 may reach 900 μatm by the end of the twenty-first century lowering the average pH of the surface ocean by 0.4 units. The negative impacts of OA on many species of marine invertebrates such as mollusks, echinoderms, and crustaceans are well documented. However, less attention has been paid to the impacts of low pH on fitness and immune system in crustaceans. Here, we exposed Pacific white shrimps to 3 different pHs (nominal pH 8.0, 7.9, and 7.6) over a 100-days experiment. We found that, even though there were no significant effects on fitness parameters (survival, growth and allometries between length and weight), some immune markers were modified under low pH. A significant decrease in total hemocyte count and phenoloxidase activity was observed in shrimps exposed to pH 7.6 as compared to pH 8.0; and phagocytosis rate significantly decreased with decreasing pH. A significant increase in superoxide production was also observed at pH 7.6 as compared to pH 8.0. All these results suggest that a 100-days exposure to pH 7.6 did not have a direct effect on fitness but lead to a modulation of the immune response.

Numerical Analysis of the Effect of Binary Typhoons on Ocean Surface Waves in Waters Surrounding Taiwan - Tzu-Yin Chang; Hongey Chen; Shih-Chun Hsiao; Han-Lun Wu; Wei-Bo Chen (Frontiers in Marine Science, 2021)
The ocean surface waves during Super Typhoons Maria (2018), Lekima (2019), and Meranti (2016) were reproduced using hybrid typhoon winds and a fully coupled wave-tide-circulation modeling system (SCHISM-WWM-III). The hindcasted significant wave heights are in good agreement with the along-track significant wave heights measured by the altimeters aboard the SARAL (Satellite with ARgos and ALtiKa) and Jason-2 satellites. Two numerical experiments pairing Super Typhoons Maria (2018) and Meranti (2016) and Super Typhoons Lekima (2019) and Meranti (2016) were conducted to analyze the storm wave characteristics of binary and individual typhoons. Four points located near the tracks of the three super typhoons were selected to elucidate the effects of binary typhoons on ocean surface waves. The comparisons indicate that binary typhoons not only cause an increase in the significant wave height simulations at four selected pints but also result in increases in the one-dimensional wave energy and two-dimensional directional wave spectra. Our results also reveal that the effects of binary typhoons on ocean surface waves are more significant at the periphery of the typhoon than near the center of the typhoon. The interactions between waves generated by Super Typhoons Maria (2018) and Meranti (2016) or Super Typhoons Lekima (2019) and Meranti (2016) might be diminished by Taiwan Island even if the separation distance between two typhoons is <700 km.

Decontamination of Uranium-Contaminated Soil by Acid Washing with Uranium Recovery - Seeun Chang; Hyun-Kyu Lee; Han-Byeol Kang; Tack-Jin Kim; Sungbin Park; Hongrae Jeon (Water, Air, & Soil Pollution, 2021)

An iterative updating heuristic search strategy for groundwater contamination source identification based on an ACPSO–ELM surrogate system - Han Wang; Wenxi Lu; Zhenbo Chang (Stochastic Environmental Research and Risk Assessment, 2021)

Nitrogen removal processes coupled with nitrification in coastal sediments off the north East China Sea - Yongkai Chang; Guoyu Yin; Lijun Hou; Min Liu; Yanling Zheng; Ping Han; Hongpo Dong; Xia Liang; Dengzhou Gao; Cheng Liu (Journal of Soils and Sediments, 2021)

Short-term exposure to air pollution and hospital admission for heart failure among older adults in metropolitan cities: a time-series study - Dong-Wook Lee; Chang-Woo Han; Yun-Chul Hong; Jong-Min Oh; Hyun-Joo Bae; Soontae Kim; Youn-Hee Lim (International Archives of Occupational and Environmental Health, 2021)

Long-term nitrogen addition further increased carbon sequestration in a boreal forest - Guancheng Liu; Guoyong Yan; Mengyu Chang; Binbin Huang; Xingyu Sun; Shijie Han; Yajuan Xing; Qinggui Wang (European Journal of Forest Research, 2021)

Tiller Outgrowth in Rice (Oryza sativa L.) is Controlled by OsGT1, Which Acts Downstream of FC1 in a PhyB-Independent Manner - Vikranth Kumar; Sung Hoon Kim; Moch Rosyadi Adnan; Jung Heo; Jin Hee Jeong; Ryza A. Priatama; Jeung Joo Lee; Chul Min Kim; Byoung Il Je; Soon Ju Park; Yuan Hu Xuan; Chang-deok Han (Journal of Plant Biology, 2021)

Effects on the STAT3-shRNA in Non-Small-Cell Lung Cancer Therapy: Design, Induction of Apoptosis, and Conjugation with Chitosan-Based Gene Vectors - Wangwang Zhang; Yan Zhang; Zhiwen Jiang; Le Sun; Litong Wang; Zhiyang Gu; Wenya Li; Lili Guo; Xiaotong Chen; Haibin Zhang; Baoqin Han; Jing Chang (Journal of Ocean University of China, 2021)

Three-dimensional dynamic sea surface modeling based on ocean wave spectrum - Zhimiao Chang; Fuxing Han; Zhangqing Sun; Zhenghui Gao; Lili Wang (Acta Oceanologica Sinica, 2021)

Eutrophication and Hypoxia in Tropical Negombo Lagoon, Sri Lanka - Hsueh-Han Hsieh; Ming-Hsiu Chuang; Yung-Yen Shih; W. Sanjaya Weerakkody; Wei-Jen Huang; Chin-Chang Hung; François L. L. Muller; R. R. M. K. P. Ranatunga; D. S. Wijethunga (Frontiers in Marine Science, 2021)
Hypoxic events are becoming frequent in some estuaries and coastal waters due to over-enrichment of anthropogenic nutrients, organic matter, and/or due to restricted water circulation. The coastal lagoons and estuaries of Sri Lanka are facing high population pressure and lacking sufficient infrastructure. Coastal lagoons may receive high anthropogenic inputs of natural or untreated nitrogen and phosphorus wastes, and consequently result in hypoxic conditions while sluggish circulation occurred. In this study, we examined the spatiotemporal variability of eutrophication and hypoxia in the Negombo Lagoon, one of the most productive and sensitive coastal ecosystems in Sri Lanka. Based on seasonal measurements of dissolved oxygen, nutrients, chlorophyll- a (Chl- a ), particulate and dissolved organic carbon (POC and DOC), we concluded that eutrophication and hypoxia occurred in both the dry and wet seasons. The main contributing factors were high seawater temperature and poor water circulation in the dry season and high nutrient loading combined with elevated POC and DOC inputs in the wet season.

Identification and spatial pattern analysis of alpine timberline by remote sensing methods in Yarlung Zangpo Grand Canyon - Bei Zhu; Shi-yan Wang; Wei Su; Kai-qi Chen; Chang Liu; Yan-liang Du; Liang Wang; Zhen Han; Jiang-xiang Zou (Journal of Mountain Science, 2021)

Hypothermal effects on expression of regucalcin, a calcium-binding protein, in the livers of seawater- and fresh water–acclimated milkfish, Chanos chanos - Chia-Hao Chang; Tsung-Han Lee (Fish Physiology and Biochemistry, 2021)

Recycle of synthetic calcium fluoride and waste sulfuric acid to produce electronic grade hydrofluoric acid - Min-Fa Lin; Jhong-Lin Wu; Ken-Lin Chang; Wen-Jhy Lee; Chih-Ping Chang; Yung-Chang Lin; Po-Han Chen (Environmental Science and Pollution Research, 2021)

Dietary Shifts and Risks of Artifact Ingestion for Argentine Shortfin Squid Illex argentinus in the Southwest Atlantic - Ssu-Wei Chang; Ruei-Gu Chen; Tsung-Han Liu; Yao-Chang Lee; Chih-Shin Chen; Tai-Sheng Chiu; Chia-Ying Ko (Frontiers in Marine Science, 2021)
Cephalopods play an important role in both ecology and fisheries. Variations in the dietary compositions of squids with large populations further promote interactions between different trophic levels in marine ecosystems. Moreover, due to marine pollution, squids are also at risks of artifact ingestion, and there is limited understanding about the influence of artifacts on the feeding behavior of squids. We examined 296 stomachs of the Argentine shortfin squid Illex argentinus collected through commercial catches across the Southwest Atlantic from February to April of 2018 and 2019 to establish the monthly dietary compositions and risks of artifact ingestion. The results supported typical observations that the Argentine shortfin squids switched from a diet dominated by crustaceans at small sizes to consuming larger prey, predominantly fishes and/or cephalopods, at large sizes during their growth and southward migration. Significantly higher consumption of fishes was observed in recent years compared with that observed in other studies since 1992. The ingested artifacts examined were composed of plastic and non-plastic materials. Artifacts were observed in 19.9% of the total number of stomachs, with 20.5% of the empty stomachs containing artifact remains. The results indicate that although the main dietary compositions of the Argentine shortfin squid maintain the taxonomic groups of prey compositions, the dietary structure, i.e., composition percentage, is varying. The detection of artifacts suggests that environmental monitoring is needed in this region in order to manage and conserve the squid and safeguard aquatic food safety.

Deep Learning Model for the Automated Detection and Histopathological Prediction of Meningioma - Hua Zhang; Jiajie Mo; Han Jiang; Zhuyun Li; Wenhan Hu; Chao Zhang; Yao Wang; Xiu Wang; Chang Liu; Baotian Zhao; Jianguo Zhang; Kai Zhang (Neuroinformatics, 2021)

Effects of rifampicin on hepatic antioxidant enzymes in PXR and CAR double humanized mice - Young Jae Choi; Chang Seon Ryu; Sang Yoon Lee; Ha Gyeong Kim; Nan Young Kim; Ji-Yoon Lee; Soo Jin Oh; Han-Jin Park; Seung-Woo Cho; Jong-Hoon Kim; Sang Kyum Kim (Molecular & Cellular Toxicology, 2021)

Simultaneous identification of groundwater contamination source and aquifer parameters with a new weighted–average wavelet variable–threshold denoising method - Han Wang; Wenxi Lu; Zhenbo Chang (Environmental Science and Pollution Research, 2021)

Effect of Depth-Induced Breaking on Wind Wave Simulations in Shallow Nearshore Waters off Northern Taiwan during the Passage of Two Super Typhoons - Shih-Chun Hsiao; Han-Lun Wu; Wei-Bo Chen; Wen-Dar Guo; Chih-Hsin Chang; Wen-Ray Su (Journal of Marine Science and Engineering, 2021)
Super Typhoons Maria (2018) and Lekima (2019) were adopted for this case study, although they only passed the northern offshore waters of Taiwan without making landfall. A direct modification technique was employed to create the atmospheric conditions for a wave-circulation model to hindcast large typhoon-driven waves. The radius of the modified scale (Rtrs) for a hybrid typhoon wind plays an important role in the significant wave height (SWH) simulations during the passage of typhoons. The maximum increment in peak SWH reached 3.0 m and 5.0 m in the deep ocean for Super Typhoons Maria (2018) and Lekima (2019), respectively if the Rtrs was increased from 4 × Rmax (radius of the maximum wind) to 7 × Rmax. The SWHs induced by the typhoon winds in the surf zone were more sensitive to different wave-breaking formulations used in the wave-circulation model. The maximum difference in peak SWH reached 2.5 m and 1.2 m for Super Typhoons Maria (2018) and Lekima (2019), respectively, when the wave-breaking formulations of BJ78 (proposed by Battjes and Janssen in 1978) and CT93 (proposed by Church and Thornton in 1993) were introduced to the wave-circulation model. The SWH simulations in the surf zone were insensitive to the wave-breaking criterion (γ) during the passage of typhoons. In shallow nearshore waters, the utilization of a constant γ for the wave-circulation model always produces peak SWHs that are smaller than those using γ based on local steepness or peak steepness.

Devonian-Carboniferous boundary in China - Wenkun Qie; Yuanlin Sun; Wen Guo; Ting Nie; Bo Chen; Junjun Song; Kun Liang; Baoan Yin; Shupeng Han; Junying Chang; Xiangdong Wang (Palaeobiodiversity and Palaeoenvironments, 2021)

Using the Metabolome to Understand the Mechanisms Linking Chronic Arsenic Exposure to Microglia Activation, and Learning and Memory Impairment - Rui-Yuan Zhang; Jie-Bai Tu; Rui-Tu Ran; Wen-Xuan Zhang; Qiang Tan; Ping Tang; Tao Kuang; Shu-Qun Cheng; Cheng-Zhi Chen; Xue-Jun Jiang; Chang Chen; Ting-Li Han; et al. (Neurotoxicity Research, 2021)

High-order conservative and oscillation-suppressing transport on irregular hexagonal grids - Han Jiao; Xindong Peng; Yuzhang Che; Jun Chang (Meteorology and Atmospheric Physics, 2021)

Identification and functional characterization of a PDR transporter in Tripterygium wilfordii Hook.f. that mediates the efflux of triptolide - Guopeng Miao; Juan Han; Yan-bo Huo; Cheng-run Wang; Shun-chang Wang (Plant Molecular Biology, 2021)

Effects of combination treatment with cilnidipine and telmisartan on hypertension, cardiovascular injury, and high blood glucose - Jun-Hwan Jo; Do-Hyung Lee; Joo-Hui Han; Miji Lee; Keun-Woo Jang; Chang-Seon Myung (Journal of Pharmaceutical Investigation, 2021)

Correction to: Pontibacter fetidus sp. nov. and Pontibacter burrus sp. nov., isolated from the soil - Yuna Park; Soohyun Maeng; Joo Hyun Han; Sang Eun Lee; Yoonjee Chang; Myung Kyum Kim (Archives of Microbiology, 2021)

Molecular characterization and expression of the SiUCP2 gene in sea urchin Strongylocentrotus intermedius - Lingshu Han; Zijiao Quan; Bing Han; Beichen Ding; Xiaofang Huang; Heng Wang; Yaqing Chang; Jun Ding (Journal of Oceanology and Limnology, 2021)

Aristololactam alkaloids from the roots of Dasymaschalon rostratum - Yue Wang; Wen-Hao Chen; Xiao-Ping Song; Chang-Ri Han (Natural Product Research, 2021)

Evidence-based Customized Ankle-Foot Orthosis with Energy Storage - Chih-Chun Lin; Chien-Hsien Yeh; Yi-Chun Tsai; Li-Chieh Kuo; Hsiu-Yun Hsu; Ping-Han Chuang; Kai Chang; Fong-Chin Su (Journal of Medical and Biological Engineering, 2021)

Dynamic shift of the epibacterial communities on commercially cultivated Saccharina japonica from mature sporophytes to sporelings and juvenile sporophytes - Qi Han; Xiaoyang Zhang; Lirong Chang; Luyang Xiao; Rafiq Ahmad; Mahasweta Saha; Hongyan Wu; Gaoge Wang (Journal of Applied Phycology, 2021)

Molecular Cloning, Expression and Characterization of Peroxisome Proliferators-Activated Receptors Gamma in the Sea Urchin (Strongylocentrotus intermedius) - Zijiao Quan; Lingshu Han; Yue Cao; Pingping Gao; Xiaoyu Liu; Yaqing Chang; Jun Ding (Journal of Ocean University of China, 2021)

Association of genetic variants of RNF213 with ischemic stroke risk in Koreans - Young Seok Park; Hyeon Woo Park; Han Sung Park; Chang Soo Ryu; Jeong Yong Lee; Eun Ju Ko; Jung Hoon Sung; Jinkwon Kim; Ok Joon Kim; Nam Keun Kim (Genes & Genomics, 2021)

New secondary metabolite with cytotoxicity from spawning soft coral Asterospicularia laurae in Taiwan - Jui-Hsin Su; Chih-I Liu; Mei-Chin Lu; Chi-I Chang; Min-Ying Hsieh; Yu-Chi Lin; Chang-Feng Dai; Ya-Han Zhang; Zheng-Yu Lin; Yun-Sheng Lin (Natural Product Research, 2021)

A review of the microseismic focal mechanism research - Han Li; Xu Chang (Science China Earth Sciences, 2021)

Plateau lake ecological response to environmental change during the last 60 years: a case study from freshwater Lake Yangzong, SW China - Han Wu; Hucai Zhang; Yanling Li; Fengqin Chang; Lizeng Duan; Xiaonan Zhang; Wei Peng; Qi Liu; Fengwen Liu; Yun Zhang (Journal of Soils and Sediments, 2021)

Simultaneous identification of groundwater contaminant sources and simulation of model parameters based on an improved single-component adaptive Metropolis algorithm - Zhenbo Chang; Wenxi Lu; Han Wang; Jiuhui Li; Jiannan Luo (Hydrogeology Journal, 2021)

Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis - Tsung-Ying Tsai; Li-Wei Lo; Shin-Huei Liu; Wen-Han Cheng; Yu-Hui Chou; Wei-Lun Lin; Yenn-Jiang Lin; Shih-Lin Chang; Yu-Feng Hu; Fa-Po Chung; Jo-Nan Liao; Tze-Fan Chao; et al. (Environmental Science and Pollution Research, 2021)

Pontibacter fetidus sp. nov. and Pontibacter burrus sp. nov., isolated from the soil - Yuna Park; Soohyun Maeng; Joo Hyun Han; Sang Eun Lee; Yoonjee Chang; Myung Kyum Kim (Archives of Microbiology, 2021)

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study - Hao Wang; Xue Han; Mei Jin; Li-yan Wang; Zong-li Diao; Wang Guo; Peng Zhang; Zheng Wang; Han Lv; He-yu Ding; Zheng-yu Zhang; Peng-fei Zhao; et al. (Brain Imaging and Behavior, 2021)

Dapagliflozin suppresses ER stress and protects doxorubicin-induced cardiotoxicity in breast cancer patients - Wei-Ting Chang; Yu-Wen Lin; Chung-Han Ho; Zhih-Cherng Chen; Ping-Yen Liu; Jhih-Yuan Shih (Archives of Toxicology, 2021)

Corrigendum: Use of Synthetic Salmon GnRH and Domperidone (Ovaprim®) in Sharks: Preparation for ex situ Conservation - Sang Wha Kim; Won Hee Hong; Se Jin Han; Jun Kwon; Heejun Ko; Sung Bin Lee; Sib Sankar Giri; Sang Guen Kim; Byung Yeop Kim; Goo Jang; Byeong Chun Lee; Dong Wan Kim; et al. (Frontiers in Marine Science, 2021)

Changes in reference evapotranspiration over the non‐monsoon region of China during 1961–2017: Relationships with atmospheric circulation and attributions - Yiyang Dong; Yong Zhao; Jiaqi Zhai; Jianshi Zhao; Jingyan Han; Qingming Wang; Guohua He; Huanyu Chang (International Journal of Climatology, 2021)
Reference evapotranspiration (ET 0 ) is an essential component of the hydrological cycle and is crucial to water resources management and assessment. Spatiotemporal variations in ET 0 and their attribution to five climatic variables (maximum and minimum air temperatures, solar radiation, vapour pressure, and wind speed) were estimated for the non‐monsoon region of China from 1961–2017 meteorological data by using the Penman–Monteith equation and the partial‐differential method. The association between ET 0 and atmospheric circulation patterns was explored by applying Pearson's correlation analysis. The annual ET 0 series had two earlier shift points, the first showing a significant increase from 1961 to 1973 (period I) and the second showing a significant decrease from 1974 to 1994 (period II). ET 0 has significantly increased again since 1994 (period III). Wind speed has been the dominant contributing factor to ET 0 followed by maximum air temperature during all three periods, but the contribution gap between minimum and maximum air temperatures is narrowing. ET 0 has been strongly correlated with eight selected teleconnection indices in some regions, but the locations and spatial extents have varied considerably for different indices. Eight relationships with ET 0 were divided into four groups: North Atlantic Oscillation and Arctic Oscillation (mainly the northwest non‐monsoon region), Pacific North American Index and Pacific Decadal Oscillation (mainly the northern non‐monsoon region), Antarctic Oscillation and Atlantic Multidecadal Oscillation (mainly the Hexi Corridor and the southern Xinjiang), and East Asian Summer Monsoon Index and South China Sea Summer Monsoon Index (mainly the southeast non‐monsoon region). The Antarctic Oscillation, Atlantic Multidecadal Oscillation, and South China Sea Summer Monsoon Index indicated more potential for predicting ET 0 . When we used Pearson's correlation analysis to analyse the relationship between atmospheric circulation and the dominant factors affecting ET 0 , we found that the circulation patterns are likely to affect the variation in ET 0 by influencing the dominant climatic variables.

Two new alkaloids from the tubers of Corydalis ambigua subsp. amurensis and their anti-proliferative activity - Zhihui Liu; Zhenru Mi; Panpan Wang; Sheng Chang; Na Han; Jun Yin (Natural Product Research, 2020)

Regulation of photosystem I-light-harvesting complex I from a red alga Cyanidioschyzon merolae in response to light intensities - Lijing Chang; Lirong Tian; Fei Ma; Zhiyuan Mao; Xiaochi Liu; Guangye Han; Wenda Wang; Yanyan Yang; Tingyun Kuang; Jie Pan; Jian-Ren Shen (Photosynthesis Research, 2020)