Cytotoxic steroidal glycosides from the rhizomes of Paris polyphylla var. yunnanensis - Yang Liu; Mei-You Liu; Lin-Lin Bi; Yun-Yuan Tian; Peng-Cheng Qiu; Xiao-Ying Qian; Min-Chang Wang; Hai-Feng Tang; Yun-Yang Lu; Bang-Le Zhang (Phytochemistry, 2023)

Early Neoproterozoic well-preserved stromatolites from southern Liaoning, North China: characteristics and paleogeographic implications - Yong-Li Zhang; Guan-Ming Lai; En-Pu Gong; Mark A. Wilson; Wen-Tao Huang; Chang-Qing Guan; Ding-Cheng Yuan (Palaeoworld, 2023)

Cobalt nanoparticles induce mitochondrial damage and β-amyloid toxicity via the generation of reactive oxygen species - Jingrong Chen; Cheng Chen; Na Wang; Chunyu Wang; Zhaohui Gong; Jingxian Du; Honglin Lai; Xinpei Lin; Wei Wang; Xiangyu Chang; Michael Aschner; Zhenkun Guo; et al. (NeuroToxicology, 2023)

One-pot generation of lignin microspheres and digestible substrate with a polyol-DES pretreatment in high solid loading - Jinyuan Cheng; Yunni Zhan; Xuze Liu; Chen Huang; Xuelian Zhou; Jia Wang; Xianzhi Meng; Chang Geun Yoo; Guigan Fang; Arthur J. Ragauskas (Journal of Cleaner Production, 2023)

Hybrid persulfate/sonocatalysis for degradation of acid orange 7 in the presence of Ag2O/CuWO4 composite: Operating parameters and sonocatalytic mechanism - Yang-Cheng Liu; Xuan Liu; Xin Wang; Zi-Hao Li; Chang-Lan Chen; Zheng Xiang (Journal of Cleaner Production, 2023)

Development of a novel resilient anchor cable and its large shear deformation performance - Chang Zhou; Cheng Huang; Youdong Chen; Qinghong Dong; Wanghua Sui (International Journal of Rock Mechanics and Mining Sciences, 2023)

Manipulating the severe shoot topping delays the harvest date and modifies the flavor composition of Cabernet Sauvignon wines in a semi-arid climate - Hao-Cheng Lu; Li Hu; Yao Liu; Chi-Fang Cheng; Wu Chen; Shu-De Li; Fei He; Chang-Qing Duan; Jun Wang (Food Chemistry, 2023)

Free astaxanthin-rich diets enhanced astaxanthin accumulation in egg yolks compared to esterified astaxanthin-rich diets - Ying-Cai Zhao; Xiao-Yue Li; Cheng-Cheng Wang; Jin-Yue Yang; Chang-Hu Xue; Tian-Tian Zhang; Yu-Ming Wang (Food Chemistry, 2023)

Volatomics of ‘Cabernet Sauvignon’ grapes and wines under the fan training system revealed the nexus of microclimate and volatile compounds - Meng-Bo Tian; Yao Liu; Hao-Cheng Lu; Li Hu; Yu Wang; Chi-Fang Cheng; Wu Chen; Shu-De Li; Fei He; Chang-Qing Duan; Jun Wang (Food Chemistry, 2023)

Effectiveness of various cacao pod husk extraction byproducts in promoting growth and immunocompetence in Litopenaeus vannamei - Chin-Chyuan Chang; Hsin-Wei Kuo; Winton Cheng (Fish & Shellfish Immunology, 2023)

Insect biorefinery: A circular economy concept for biowaste conversion to value-added products - Phei Er Kee; Yu-Shen Cheng; Jo-Shu Chang; Hip Seng Yim; John Choon Yee Tan; Su Shiung Lam; John Chi-Wei Lan; Hui Suan Ng; Kuan Shiong Khoo (Environmental Research, 2023)

The impact of hazes on schizophrenia admissions and the synergistic effect with the combined atmospheric oxidation capacity in Hefei, China - Jiajun Yuan; Weiwei Chang; Zhenhai Yao; Liying Wen; Jintao Liu; Rubing Pan; Weizhuo Yi; Jian Song; Shuangshuang Yan; Xuanxuan Li; Li Liu; Ning Wei; et al. (Environmental Research, 2023)

Exploring the heterogeneity in drivers of energy-saving behaviours among hotel guests: Insights from the theory of planned behaviour and personality profiles - Qian-Cheng Wang; Yi-Tian Ren; Xuan Liu; Rui-Dong Chang; Jian Zuo (Environmental Impact Assessment Review, 2023)

Nitrogen and boron co-doped lignin biochar for enhancing calcium peroxide activation toward organic micropollutants decontamination in waste activated sludge and related microbial structure dynamics - Chang-Mao Hung; Chiu-Wen Chen; Chin-Pao Huang; Cheng-Di Dong (Bioresource Technology, 2023)

Combinatorial metabolic engineering and tolerance evolving of Escherichia coli for high production of 2′-fucosyllactose - Xue Sun; Zetao Peng; Chang Li; Yanling Zheng; Ya'nan Cheng; Jianfei Zong; Fuping Lu; Yu Li; Qinggang Li (Bioresource Technology, 2023)

Taxonomic Revision of the Genus Croaker Johnius (Perciformes: Sciaenidae) in Taiwanese Waters - Norhafiz Hanafi; Meng-Hsien Chen; Ying Giat Seah; Chih-Wei Chang; Shang Yin Vanson Liu; Chien-Cheng Lai; Ning Labbish Chao (Journal of Marine Science and Engineering, 2023)
Given the identification of the new species Johnius taiwanesis, the Johnius genus in Taiwanese water is here reviewed through a collection of field samples, museum specimens, and a review of the Taiwanese scientific literature. Seven valid Johnius species were successfully identified and distinguished based on gill raker length, tip of upper jaw to mouth hinge length, tip of lower jaw to mouth hinge length, and length of second spine of anal fin. Our phylogenetic tree based on cytochrome oxidase subunit I (COI) showed the existence of high interspecific genetic diversity within the genus Johnius forming a monophyletic group. The Johnius species in Taiwan are mainly distributed in a latitude ranging from Xingda (22.4° N) to Hsinchu (24.8° N) with J. taiwanensis, J. distinctus, and J. belangerii representing the most abundant species caught throughout the year. Johnius amblycephalus and J. borneensis were only caught in the summer, while J. trewavasae was rarely caught. In conclusion, we provide a dichotomous key for the genus Johnius in Taiwan waters.

Chemical investigations and cytotoxic effects of metabolites from Antrodia camphorata against human hepatocellular carcinoma cells - Yih-Fung Chen; Ho-Cheng Wu; Jia-Min Chang; Horng-Huey Ko; Chu-Hung Lin; Hsun-Shuo Chang (Natural Product Research, 2023)

Effects of consumer perceptions on carbon-offset payment through mediating and moderating mechanisms - Bao Quoc Truong-Dinh; Tessa Tien Nguyen; Tzu-Chang Forrest Cheng; Julian Ming-Sung Cheng (Transportation Research Part D: Transport and Environment, 2023)

Ambient relative humidity-dependent obstructive sleep apnea severity in cold season: A case-control study - Kuan-Jen Bai; Wen-Te Liu; Yuan-Chien Lin; Yansu He; Yueh-Lun Lee; Dean Wu; Ta-Yuan Chang; Li-Te Chang; Chun-Yeh Lai; Cheng-Yu Tsai; Kian Fan Chung; Kin-Fai Ho; et al. (Science of The Total Environment, 2023)

A novel ultrasensitive and fast aptamer biosensor of SEB based on AuNPs-assisted metal-enhanced fluorescence - Xueyu Chang; Yaqian Cheng; Xinke Wang; Yonghui Wang; Xueli Liu; Tie Han; Zhixian Gao; Huanying Zhou (Science of The Total Environment, 2023)

Application of an improved maximum entropy sampling method in hull form optimization - Xuyu Ouyang; Haichao Chang; Baiwei Feng; Zuyuan Liu; Chengsheng Zhan; Xide Cheng (Ocean Engineering, 2023)

A PSR-AHP-GE model for evaluating environmental impacts of spoil disposal areas in high-speed railway engineering - Baoquan Cheng; Ruidong Chang; Quanhua Yin; Jianchang Li; Jianling Huang; Huihua Chen (Journal of Cleaner Production, 2023)

A colon-targeted delivery system of torularhodin encapsulated in electrospinning microspheres, and its co-metabolic regulation mechanism of gut microbiota - Chang Liu; Yahui Guo; Yuliang Cheng; He Qian (Food Hydrocolloids, 2023)

Torularhodin bilosomes attenuate high-fat diet-induced chronic kidney disease in mice by regulating the TLR4/NF-κB pathway - Ciwan Wang; Chang Liu; Wenqian Xu; Yuliang Cheng; Yahui Guo; Yong Zhao; Fanglin Shen; He Qian (Food Bioscience, 2023)

Seasonal and source characteristics of organophosphorus flame retardants in air and house dust in Taiwan residential microenvironments: Implications for young children's exposure and risk assessment using a probabilistic approach - Quang-Oai Lu; Chien-Cheng Jung; Yu-Hsuan Liu; Wei-Hsiang Chang (Environmental Pollution, 2023)

Enhanced production of high-value polyunsaturated fatty acids (PUFAs) from potential thraustochytrid Aurantiochytrium sp. - Ajeet Singh Chauhan; Anil Kumar Patel; Chiu-Wen Chen; Jo-Shu Chang; Philippe Michaud; Cheng-Di Dong; Reeta Rani Singhania (Bioresource Technology, 2023)

Microbial community structure and potential function associated with poly-3-hydroxybutyrate biopolymer-boosted activation of peroxymonosulfate for waste-activated sludge decontamination - Chang-Mao Hung; Chiu-Wen Chen; Chin-Pao Huang; Der-Shyan Sheu; Cheng-Di Dong (Bioresource Technology, 2023)

Removal of heavy metal vanadium from aqueous solution by nanocellulose produced from Komagataeibacter europaeus employing pineapple waste as carbon source - Yi Sheng Tseng; Reeta Rani Singhania; Ann-Chang Cheng; Chiu-Wen Chen; Cheng-Di Dong; Anil Kumar Patel (Bioresource Technology, 2023)

Study on adsorption of ammonium and nitrate in wastewater by modified biochar - Jih-Hsing Chang; PratimaDevi Sivasubramanian; Cheng-Di Dong; Mohanraj Kumar (Bioresource Technology Reports, 2023)

Correction: RNA m6A methylation promotes the formation of vasculogenic mimicry in hepatocellular carcinoma via Hippo pathway - Kailiang Qiao; Yantao Liu; Zheng Xu; Haohao Zhang; Heng Zhang; Chao Zhang; Zhi Chang; Xinyan Lu; Zhongwei Li; Ce Luo; Yanrong Liu; Cheng Yang; et al. (Angiogenesis, 2023)

Ectopic expression of MmCYP1A1, a mouse cytochrome P450 gene, positively regulates stress tolerance in apple calli and Arabidopsis - Xiao-Na Wang; Fei Yang; Jiu-Cheng Zhang; Yi-Ran Ren; Jian-Ping An; Da-Yong Chang; Xiao-Fei Wang; Chun-Xiang You (Plant Cell Reports, 2023)

Pathology, Enzyme Activity and Immune Responses after Cryptocaryon irritans Infection of Golden Pompano Trachinotus ovatus (Linnaeus 1758) - Hua-Yang Guo; Wen-Fu Li; Ke-Cheng Zhu; Bao-Suo Liu; Nan Zhang; Bo Liu; Jing-Wen Yang; Dian-Chang Zhang (Journal of Marine Science and Engineering, 2023)
Golden pompano (Trachinotus ovatus) has become an economically important fish in China in the past decade. However, Cryptocaryon irritans, a parasitic ciliate, causes considerable economic losses in the mariculture of T. ovatus. To characterize the pathogenesis of C. irritans in T. ovatus, the pathological properties, immune-related enzyme activity and expression of the NEMO gene was analysed. The results from the histological sections showed that there was considerable metamorphosis and hyperplasia in the parasitized sites (skin) with leukocyte aggregation and mucous cell increases after C. irritans infection. Moreover, the activities of four enzymes, that is, alkaline phosphatase (AKP), acid phosphatase (ACP), superoxide dismutase (SOD) and lysozyme (LZM), were significantly increased in different tissues after C. irritans infection. Furthermore, the ORF of T. ovatus NF-kappa-B essential modulator (ToNEMO) measures 1650 bp, encoding 548 amino acids. The ToNEMO transcripts were universally expressed in all examined tissues, with higher levels being observed in the immune-relevant and central nervous tissues. The mRNA levels of ToNEMO after C. irritans infection were significantly increased in the gill, skin, liver, spleen and head kidney. These results suggested that ToNEMO might be involved in immune responses and helped to elucidate the physiological response after the C. irritans infection of fish.

Targeted isolation of antitubercular cycloheptapeptides and an unusual pyrroloindoline-containing new analog, asperpyrroindotide A, using LC–MS/MS-based molecular networking - Yi-Qian Han; Qun Zhang; Wei-Feng Xu; Yang Hai; Rong Chao; Cui-Fang Wang; Xue-Mei Hou; Mei-Yan Wei; Yu-Cheng Gu; Chang-Yun Wang; Chang-Lun Shao (Marine Life Science & Technology, 2023)
Further insights on the secondary metabolites of a soft coral-derived fungus Aspergillus versicolor under the guidance of MS/MS-based molecular networking led to the isolation of seven known cycloheptapeptides, namely, asperversiamides A–C ( 1 – 3 ) and asperheptatides A–D ( 4 – 7 ) and an unusual pyrroloindoline-containing new cycloheptapeptide, asperpyrroindotide A ( 8 ). The structure of 8 was elucidated by comprehensive spectroscopic data analysis, and its absolute configuration was determined by advanced Marfey’s method. The semisynthetic transformation of 1 into 8 was successfully achieved and the reaction conditions were optimized. Additionally, a series of new derivatives ( 10 − 19 ) of asperversiamide A ( 1 ) was semi-synthesized and their anti-tubercular activities were evaluated against Mycobacterium tuberculosis H37Ra. The preliminary structure−activity relationships revealed that the serine hydroxy groups and the tryptophan residue are important to the activity.

Research on the Karhunen–Loève Transform Method and Its Application to Hull Form Optimization - Haichao Chang; Chengjun Wang; Zuyuan Liu; Baiwei Feng; Chengsheng Zhan; Xide Cheng (Journal of Marine Science and Engineering, 2023)
Hull form optimization becomes prone to the curse of dimensionality as the number of design variables increases. The traditional sensitivity analysis method requires massive computational fluid dynamics (CFD) computations and analyzing the effects of all variables on the output; thus, it is extremely time-consuming. Considering this, the development of a rapid and effective dimensionality reduction method is particularly important. The Karhunen–Loève (K–L) transform method projects data from a high-dimensional space onto a low-dimensional space in the direction of the eigenvectors corresponding to large-variance eigenvalues. It extracts the principal components that represent the hull offset information to represent the hull geometric characteristics by analyzing the relationship between the variables in the sample offset matrix. The geometric information matrices of new hull forms can be rapidly reconstructed from the principal components. Compared with direct optimization methods, fewer variables are used to control the deformation of the hull form from the perspective of geometric deformation, avoid a large number of CFD calculations, and improve the efficiency of optimization. This study examined the relevant K–L matrix solution methods and the corresponding hull form reconstruction methods and proposed eigenvalue-based hull form reconstruction equations. The K–L transform method was combined with a previously developed multidisciplinary platform for a comprehensive optimization of ship hydrodynamic performance for hull form optimization, and its effectiveness was verified by using it to optimize DTMB 5415. The results showed that the K–L transform–based dimensionality reduction method significantly reduces the time consumption of optimization while maintaining an acceptable optimization performance.

Transcriptome Analysis of the Immune Process of Golden Pompano (Trachinotus ovatus) Infected with Streptococcus agalactiae - Jie Gao; Hua-Yang Guo; Ming-Jian Liu; Ke-Cheng Zhu; Bo Liu; Bao-Suo Liu; Nan Zhang; Shi-Gui Jiang; Dian-Chang Zhang (Fishes, 2023)
The golden pompano (Trachinotus ovatus) is one of the most economically valuable marine fishes in South China. Streptococcus agalactiae, an infectious Gram-positive bacterium that is highly destructive for golden pompano culture, has recently caused massive losses to the golden pompano industry. This study aimed to investigate the dynamic immune response of golden pompano to S. agalactiae infection, using RNA-seq analysis at two different time points after infection. Abundances of differentially expressed genes (DEGs) gradually increased in the liver and spleen 48–120 h post-infection, whereas those in the head kidney were lower at 120 h than at 48 h. Pathway enrichment analysis of DEGs revealed that genes related to the complement system were continuously transcribed between 48 and 120 h. Metabolic and immune-regulation-related pathways were highly enriched in the liver 48 h after infection. Transcriptome analysis was verified using quantitative PCR for eight genes with similar expression trends. This study revealed the inflammatory response of golden pompano after S. agalactiae infection, including inflammation-related chemokines and signaling pathways. Our findings provide a theoretical basis for studying S. agalactiae resistance in golden pompano and provide a reliable resource for the genetic breeding of fish.

Black soldier fly larvae replace traditional iced trash fish diet to enhance the delicious flavor of Chinese mitten crab (Eriocheir sinensis) - Jian-Feng Qiu; Cheng Luo; Li-Hua Ren; Wei Li; Tai-Ming Dai; Guang Wang; Xiao-Ning Sun; Kou-Chang Chong Moua; Yang-Hu Sima; Shi-Qing Xu (Frontiers in Marine Science, 2023)
Chinese mitten crabs ( Eriocheir sinensis ) are traditionally fed iced trash fish, but the industry is facing problems such as low breeding safety. Black soldier fly ( Hermetia illucens ) is an alternative protein source in animal diets, including diets for aquatic animals, due to its high nutritional value. However, studies on the effects of black soldier fly on the flavor characteristics of aquatic animals are still limited. In the present study, we investigated the effects of the complete replacement of iced trash fish with black soldier fly larvae during the fattening period of Chinese mitten crab on the flavor molecule contents and evaluation indices. The levels of free amino acids and nucleotides were determined in three edible parts (muscle, hepatopancreas, and gonads) of crab. Taste activity value analysis showed that glutamic acid, glycine, alanine, and arginine were the main amino acids contributing to the umami taste and sweetness, while histidine, lysine, valine, and methionine were the main amino acids contributing to the bitterness. Equivalent umami concentration (EUC) analysis showed that female gonads had the strongest umami taste, followed by the hepatopancreas and muscle. Sweetness value (SWT) analysis showed that the sweetness of muscle was the highest. Feeding black soldier fly larvae affected the flavor characteristics of crabs with tissue and sex differences. The EUC of the female gonads and SWT of the muscle were significantly increased. Meanwhile, the EUC of the hepatopancreas and SWT of the gonads were slightly decreased in male crabs. Our results indicate that the complete replacement of iced trash fish with black soldier fly larvae during the fattening period significantly enhances the flavor characteristics of crabs based on the contents of flavoring amino acids and nucleotides. It is important for sustainable aquaculture to replace animal protein with alternative protein sources such as black soldier fly larvae.

Corrigendum to “Grafting with an invasive Xanthium strumarium improves tolerance and phytoremediation of native congener X. sibiricum to cadmium/copper/nickel tailings” [Chemosphere, 308 (2022) 136561] - Chenyang Xue; Lizong Sun; Bo Qu; Yingmei Gao; Zhi Liu; Cheng Guo; Wanbin Liu; Wenyue Chang; Peidong Tai (Chemosphere, 2023)

Characteristics of microplastic pollution in golden pompano (Trachinotus ovatus) aquaculture areas and the relationship between colonized-microbiota on microplastics and intestinal microflora - Ming-Jian Liu; Hua-Yang Guo; Jie Gao; Ke-Cheng Zhu; Liang Guo; Bao-Suo Liu; Nan Zhang; Shi-Gui Jiang; Dian-Chang Zhang (Science of The Total Environment, 2023)

Infusing satellite data into aerosol forecast for near real-time episode detection and diagnosis in East Asia - Sheng-Po Chen; Cheng-Hsuan (Sarah) Lu; James E. Davies; Chang-Feng Ou-Yang; Neng-Huei Lin; Amy K. Huff; Bradley R. Pierce; Shobha Kondragunta; Jia-Lin Wang (Science of The Total Environment, 2023)

Corrigendum to “Comparative efficacy of omega-3 polyunsaturated fatty acids on major cardiovascular events: A network meta-analysis of randomized controlled trials” [Progress in Lipid Research. 2022 Oct 28;88:101196. doi: 10.1016/j.plipres.2022.101196] - Bo Yang; Ping-Tao Tseng; Xiang Hu; Bing-Yan Zeng; Jane Pei-Chen Chang; Yang Liu; Wei-Jie Chu; Shuang-Shuang Zhang; Zhi-Liang Zhou; Chih-Sheng Chu; Cheng-Ho Chang; Yu-Kang Tu; et al. (Progress in Lipid Research, 2023)

Microbiome reengineering by four environmental factors for the rapid biodegradation of trichloroethylene - Yu-Hsuan Cheng; Shu-Chi Chang; Yan-Lin Lai; Chung-Chi Hu (Journal of Environmental Management, 2023)

Region, vintage, and grape maturity co-shaped the ionomic signatures of the Cabernet Sauvignon wines - Xiao Han; Hao-Cheng Lu; Yu Wang; Xiao-Tong Gao; Hui-Qing Li; Meng-Bo Tian; Ning Shi; Ming-Yu Li; Xiao-Li Yang; Fei He; Chang-Qing Duan; Jun Wang (Food Research International, 2023)

Performance and mechanism of a novel S-scheme heterojunction sonocatalyst CuS/BaWO4 for degradation of bisphenol A by ultrasonic activation - Yang-Cheng Liu; Xuan Liu; Gui-Hong Zhang; Wei Liu; Jia-Qi Wang; Xin Wang; Chang-Lan Chen; Yang Wang; Zheng Xiang (Environmental Research, 2023)

The remediation of di-(2-ethylhexyl) phthalate-contaminated sediments by water hyacinth biochar activation of calcium peroxide and its effect on cytotoxicity - Chang-Mao Hung; Chin-Pao Huang; Shu-Ling Hsieh; Ya-Ting Chen; Chiu-Wen Chen; Cheng-Di Dong (Environmental Research, 2023)

Using cluster algorithms with a machine learning technique and PMF models to quantify local-specific origins of PM2.5 and associated metals in Taiwan - Chin-Yu Hsu; Jhy-Charm Soo; Sheng-Lun Lin; Chih-Da Wu; Kai Hsien Chi; Wen-Chang Hsu; Chun-Chieh Tseng; Yu-Cheng Chen (Environmental Pollution, 2023)

Distribution and toxicity of submicron plastic particles in mice - Tsung-Yen Tsou; Sheng-Han Lee; Tzu-Hsuan Kuo; Chu-Chun Chien; Hsin-Chang Chen; Tsun-Jen Cheng (Environmental Toxicology and Pharmacology, 2023)

Pricing strategy for household energy-saving option (HESO): A novel option-based intervention for promoting household energy efficiency - Qian Xu; Shengping Li; Liyin Shen; Ruidong Chang; Qian-Cheng Wang; Xuan Liu; Yang Chen (Environmental Impact Assessment Review, 2023)

Demystifying viscous isoalkanes as the organic solvent in interfacial polymerization for manufacturing desalination membranes - Zhao-Yu Ma; Chang Liu; Yu-Ren Xue; Cheng-Ye Zhu; Jian Wu; Zhi-Kang Xu (Desalination, 2023)

Evaluation of LiNiO2 with minimal cation mixing as a cathode for Li-ion batteries - Rio Akbar Yuwono; Fu-Ming Wang; Nae-Lih Wu; Yan-Cheng Chen; Hsi Chen; Jin-Ming Chen; Shu-Chih Haw; Jyh-Fu Lee; Rui-Kun Xie; Hwo-Shuenn Sheu; Po-Ya Chang; Chusnul Khotimah; et al. (Chemical Engineering Journal, 2023)

Removal of heavy metals from water by macro-mesoporous calcium alginate–exfoliated clay composite sponges - Shella Permatasari Santoso; Alfin Kurniawan; Artik Elisa Angkawijaya; Hardy Shuwanto; I.D.A.A. Warmadewanthi; Chang-Wei Hsieh; Hsien-Yi Hsu; Felycia Edi Soetaredjo; Suryadi Ismadji; Kuan-Chen Cheng (Chemical Engineering Journal, 2023)

Construction of a single-atom palladium catalyst by electronic metal-support interaction and interface confinement effect with remarkable performance in Suzuki coupling reaction - Siqi Ji; Xiaowen Lu; Mingyang Zhang; Leipeng Leng; Hongxue Liu; Kuibo Yin; Chang Xu; Cheng He; J. Hugh Horton; Jiangwei Zhang; Zhijun Li (Chemical Engineering Journal, 2023)

Molten salt-induction of geometrically deformed ruthenium single atom catalysts with high performance for aerobic oxidation of alcohols - Xiuli Dong; Yufei Jia; Mingyang Zhang; Siqi Ji; Leipeng Leng; J. Hugh Horton; Chang Xu; Cheng He; Qiang Tan; Jiangwei Zhang; Zhijun Li (Chemical Engineering Journal, 2023)

Amygdalin alleviated TGF-β-induced epithelial-mesenchymal transition in bronchial epithelial cells - An-nan Zhang; Nan Li; Zhuo-chang Chen; Ya-li Guo; Cui-jie Tian; Dong-jun Cheng; Xue-yi Tang; Xiao-yu Zhang (Chemico-Biological Interactions, 2023)

CmHY5 functions in apigenin biosynthesis by regulating flavone synthase II expression in chrysanthemum flowers - Chang Luo; Lei Liu; Jian Zhao; Yanjie Xu; Hua Liu; Dongliang Chen; Xi Cheng; Junping Gao; Bo Hong; Conglin Huang; Chao Ma (Planta, 2023)

Attenuation of experimental osteoarthritis with human adipose-derived mesenchymal stem cell therapy: inhibition of the pyroptosis in chondrocytes - Liang Xu; Feng Zhang; Gang Cheng; Xiaoyang Yuan; Yujiao Wu; Huaxun Wu; Qingtong Wang; Jingyu Chen; Jiajie Kuai; Yan Chang; Wei Wei; Shangxue Yan (Inflammation Research, 2023)

Gas-phase and PM2.5-bound phthalates in nail salons: characteristics, exposure via inhalation, and influencing factors - Chia-Ling Chang; Hui-Tzu Chen; Chung-Yu Chen; En-Yu Chen; Kuan-Ting Lin; Chien-Cheng Jung (Environmental Science and Pollution Research, 2023)

A symbiosis between Euploea butterflies and yeasts - Wan-Rou Lin; Yi-Ping Chang; Hui-Lin Wu; I-Cheng Hsu; Pi-Han Wang (Symbiosis, 2023)

Step Approximation on Water Wave Breaking and Dissipation over Variable Bottoms across the Surf Zone - Jen-Yi Chang; Chia-Cheng Tsai (Journal of Marine Science and Engineering, 2023)
This study investigates the combined effect of the breaking and energy dissipation of water waves by variable bottoms across the surf zone. The shoreline is set up as a partially reflecting vertical wall in the solution technique, with shelves between the steps that approximate the geometric profile of the varied bottom over the surf zone. The eigenfunctions over the shelves are matched on the connecting step using the conservations of mass and momentum. The impacts of breaking and energy dissipation are implemented in the proposed eigenfunction matching method using the energy-dissipation factors, which are modeled by empirical formulas. The proposed model is validated by comparing its results with the experimental data available in the literature. Some benchmark results of wave scattering by a rectangular breakwater near a partially reflecting vertical wall are provided and discussed. In addition, wave breaking and dissipation in the proposed model using different empirical formulas are discussed.

Interaction between the parasitic barnacle Polyascus planus (Cirripedia: Rhizocephala) and its brachyuran host Metopograpsus thukuhar during the development of the externa of the parasite: Control of the gonadal development and vitellogenin synthesis of the host - Hsiang-Yin Chen; Chien-Hsun Lee; Chih-Cheng Tsai; Hung-Chang Liu; Su-Ling Yang; Chi-Ying Lee (Frontiers in Marine Science, 2022)
Developmental profile of the female reproductive apparatus (the externa) of Polyascus planus parasitizing the thukuhar shore-crab Metopograpsus thukuhar is described. The development is divided into 4 stages, which are named based on the distinct color of the externa at each stage. The effects of parasitism on the gonad and hepatopancreas of the host were then examined. The ovary was heavily infiltrated by the rootlet of the parasite, with the oocytes being arrested at the pre-vitellogenic state, whereas the testis, not being infiltrated, still contained abundant amounts of spermatozoa. The hepatopancreas of the hosts of both sexes was heavily infiltrated by the rootlets. Regarding the synthesis of vitellogenin (Vg), the hemolymph precursor of the major yolk protein (vitellin, Vn), expression of host Vg gene was detected in the ovary and hepatopancreas of both non-parasitized and parasitized females, and, importantly, its expression found to be induced in the hepatopancreas of parasitized males. Furthermore, results of quantitative gene expression assays showed that expression levels of the host Vg in the ovary and hepatopancreas did not change significantly among the various parasitization status (i.e., host bearing externa of different developmental stages), nor did those of the parasite Vg in the externa among the developmental stage of the externa. The Vg expression levels in the hepatopancreas of parasitized males and in the externa were however negatively correlated. Finally, analysis of tryptic peptide fragments derived from hemolymph proteins of high molecular weight in the parasitized males confirmed the induction of synthesis of the host Vg, whereas analysis of externa proteins of similar molecular weight revealed that Vg of both host and parasite origins contributes to the formation of parasite Vn. The combined results indicate that the parasitized hosts, regardless of sex, synthesize Vg for the ovarian maturation of the parasite, to which Vg of parasite origin also contributes. Discussion is also made with regard to the strategy the parasite adopts toward hosts of different sexes. The profile of the development of externa established would serve as a temporal framework against which studies of host/parasite interaction can be conducted in a developmental context.

Development of integrated multitrophic aquaculture–based cage rearing system in an underutilized fishing port and its application in marine stock enhancement - Hung-Tai Lee; Yung-Cheng Chang; Cheng-Hsin Liao; Te-Hua Hsu (Frontiers in Marine Science, 2022)
Human activity and global climate change have severely affected marine ecosystems and fishery resources. Habitat conservation and stock enhancement are considered effective methods. Moreover, with the gradual disappearance of fishery resources, fishing ports have become underutilized spaces. Currently, 73 of the 221 fishing ports in Taiwan are underutilized. Therefore, we, for the first time, developed an integrated multitrophic aquaculture (IMTA)-based cage rearing system suitable for stock enhancement and applied it in an optimal underutilized fishing port after the site evaluation and selection of 17 potential fishing ports fishing. We further tested that hypothesis that hatchery-produced organisms can be reared and monitored appropriately in this cage rearing system with good survival and growth as well as less environmental impact and handling stress. Through the collocation of various release organisms of different trophic levels, the cage rearing system can reduce environmental impacts as evidenced by the steady water quality (stable pH and undetectable levels of ammonia nitrogen, nitrates, and nitrites). As for the fish welfare, this semiartificial rearing system could also reduce the discomforts of hatchery-produced organisms after transportation and facilitate their adaptations to the released environments as evidenced by positive growth and high survival rates (94%–98%). The cultured and naturally grown shellfish and algae on the cage nets could provide habitats for hatchery-produced and wild organisms that facilitate habitat conservation and stock enhancement. Taken together, we have demonstrated that it is feasible to implement this novel IMTA-based cage rearing system in an underutilized fishing port required for marine stock enhancement.

Mesenchymal Stem Cell Secreted-Extracellular Vesicles are Involved in Chondrocyte Production and Reduce Adipogenesis during Stem Cell Differentiation - Yu-Chen Tsai; Tai-Shan Cheng; Hsiu-Jung Liao; Ming-Hsi Chuang; Hui-Ting Chen; Chun-Hung Chen; Kai-Ling Zhang; Chih-Hung Chang; Po-Cheng Lin; Chi-Ying F. Huang (Tissue Engineering and Regenerative Medicine, 2022)
Background: Extracellular vesicles (EVs) are derived from internal cellular compartments, and have potential as a diagnostic and therapeutic tool in degenerative disease associated with aging. Mesenchymal stem cells (MSCs) have become a promising tool for functional EVs production. This study investigated the efficacy of EVs and its effect on differentiation capacity. Methods: The characteristics of MSCs were evaluated by flow cytometry and stem cell differentiation analysis, and a production mode of functional EVs was scaled from MSCs. The concentration and size of EVs were quantitated by Nanoparticle Tracking Analysis (NTA). Western blot analysis was used to assess the protein expression of exosome-specific markers. The effects of MSC-derived EVs were assessed by chondrogenic and adipogenic differentiation analyses and histological observation. Results: The range of the particle size of adipose-derived stem cells (ADSCs)- and Wharton’s jelly -MSCs-derived EVs were from 130 to 150 nm as measured by NTA, which showed positive expression of exosomal markers. The chondrogenic induction ability was weakened in the absence of EVs in vitro . Interestingly, after EV administration, type II collagen, a major component in the cartilage extracellular matrix, was upregulated compared to the EV-free condition. Moreover, EVs decreased the lipid accumulation rate during adipogenic induction. Conclusion: The results indicated that the production model could facilitate production of effective EVs and further demonstrated the role of MSC-derived EVs in cell differentiation. MSC-derived EVs could be successfully used in cell-free therapy to guide chondrogenic differentiation of ADSC for future clinical applications in cartilage regeneration.

Pollution characteristics and health risk assessment of PM2.5-bound arsenic: a 7-year observation in the urban area of Jinan, China - Shaofeng Sui; Yanxin Gao; Tao Yuan; Chang He; Cheng Peng; Yan Wang; Zhiyan Liu (Environmental Geochemistry and Health, 2022)

Correction to: Non-normal distribution of radon and residual radon and short-term abnormal precursors of residual radon before major earthquakes - Xiaobing Jin; Junwei Bu; Guilan Qiu; Li Ma; Zhongming Chen; Tao Chen; Junwei Wu; Bo Pan; Hai Ji; Jingxuan Tian; Xiaoxiao Wu; Zhipeng Li; et al. (Earth Science Informatics, 2022)

Non-normal distribution of radon and residual radon and short-term abnormal precursors of residual radon before major earthquakes - Xiaobing Jin; Junwei Bu; Guilan Qiu; Li Ma; Zhongming Chen; Tao Chen; Junwei Wu; Bo Pan; Hai Ji; Jingxuan Tian; Xiaoxiao Wu; Zhipeng Li; et al. (Earth Science Informatics, 2022)

Numerical Simulation of the Maneuvering Motion Wake of an Underwater Vehicle in Stratified Fluid - Chang Shi; Xide Cheng; Zuyuan Liu; Kunyu Han; Penghui Liu; Long Jiang (Journal of Marine Science and Engineering, 2022)
When a vehicle moves underwater, disturbance is generated and a wake remains that destroys the original free surface and produces a new wake. In order to study the mechanism and characteristics of the wave-making wake generated by the maneuvering motion of an underwater vehicle in density-stratified fluid, the k-ε model and the VOF method that is based on the RANS equation were used in this paper to analyze the SUBOFF model in stratified fluid at different drift angles. Numerical simulation of the maneuvering motion was carried out under these angles, and the corresponding changes in flow field caused by this motion were analyzed. The results from the comparison and analysis of the surface wave wakes under different drift angles in stratified fluid show that with the increasing drift angle, the motion wake of the vehicle still exhibits obvious Kelvin wave system characteristics. However, there are significant changes in hydrodynamic performance. The asymmetry of the surrounding flow field will increase with the increase in the drift angle. The pressure of the underwater vehicle is inversely proportional to the velocity of the surrounding flow field, and the amplitude of the peak and trough of the free surface wave is linearly related to the change in the drift angle. The numerical simulation can serve as a reference for the non-acoustic detection of the motion heading of an underwater vehicle and the motion trajectory of anti-reconnaissance underwater vehicles under actual sea conditions.

Protective effect of ginsenoside Rd on military aviation noise-induced cochlear hair cell damage in guinea pigs - Xue-min Chen; Yu-hui Liu; Shuai-fei Ji; Xin-miao Xue; Lin-lin Wang; Min Zhang; Yao-ming Chang; Xiao-cheng Wang (Environmental Science and Pollution Research, 2022)

A 10-miRNA risk score-based prediction model for pathological complete response to neoadjuvant chemotherapy in hormone receptor-positive breast cancer - Chang Gong; Ziliang Cheng; Yaping Yang; Jun Shen; Yingying Zhu; Li Ling; Wanyi Lin; Zhigang Yu; Zhihua Li; Weige Tan; Chushan Zheng; Wenbo Zheng; et al. (Science China Life Sciences, 2022)

Distribution of ultrafine aerosols and volatile organic compounds from surgical smoke during electrocauterization - Chi-Tsung Chen; Shiang-Fu Huang; Cheng-Jung Li; Jou-Mien Huang; Kai-Ping Chang; Gwo-Hwa Wan (Air Quality, Atmosphere & Health, 2022)

Surfactin isoforms isolated from a mushroom derived Bacillus halotolerans DMG-7-2 - Guo-Feng Zhou; Lin Yang; Shu-Hua Zhang; Yi Wang; Yu Yang; Rui Xu; Xue Zhao; Dan Nie; Junjie Shan; Cheng-Bin Cui; Chang-Wei Li (Natural Product Research, 2022)

Plasma Matrix Metalloproeteinase-9 Is Associated with Seizure and Angioarchitecture Changes in Brain Arteriovenous Malformations - Yo-Tsen Liu; Cheng-Chia Lee; Chun-Fu Lin; Hsiu-Mei Wu; Wan-Yuo Guo; Huai-Che Yang; Feng-Chi Chang; Kang-Du Liou; Chung-Jung Lin (Molecular Neurobiology, 2022)

Greenhouse gas emission benefits of adopting new energy vehicles in Suzhou City, China: A case study - Cui Da; Xinyu Gu; Chunchen Lu; Ruiqi Hua; Xinyue Chang; Yuanyuan Cheng; Feiyue Qian; Yiheng Wang (Environmental Science and Pollution Research, 2022)

Artificial consortia of Bacillus amyloliquefaciens HM618 and Bacillus subtilis for utilizing food waste to synthetize iturin A - Chang-Hao Miao; Xiao-Feng Wang; Bin Qiao; Qiu-Man Xu; Chun-Yang Cao; Jing-Sheng Cheng (Environmental Science and Pollution Research, 2022)

Multi-cutting and sheep excrement influence plant growth and soil nitrogen mineralization in sown grassland - Xinzhou Zhao; Lina Shi; Shenghua Chang; Cheng Zhang; Shicheng Yan; Wuchen Du; Qianmin Jia; Fujiang Hou (Plant and Soil, 2022)

Use of an Effective Variance Chemical Mass Balance Model for Source Apportionment of Metal Elements in a Polluted River - Pei-Yuan Hsieh; Chi-Chang Ho; Gen-Shuh Wang; Yuan-Cheng Hsu; Di-Wen Wang; Yu-Man Shang; Chang-Fu Wu (Environmental Processes, 2022)

Particle breakage mechanism and particle shape evolution of calcareous sand under impact loading - Xing Wang; Ying Wang; Cheng Liao; Jie Cui; Jian-Hua Shen; Xin-Zhi Wang; Chang-Qi Zhu (Bulletin of Engineering Geology and the Environment, 2022)

Analysis of lateral orbitofrontal cortex activation on acquisition of fear extinction and neuronal activities in fear circuit - Cheng-Chia Shih; Yu-Hsuan Chang; Ruei-Jen Chiou; Chun-hui Chang (Brain Structure and Function, 2022)

Home Composting for Onsite Treatment of Household Organic Solid Waste: A Review - Jingwen Cheng; Rongrong Yin; Wenhai Luo; Yanming Li; Lingxiao Wang; Ruixue Chang (Current Pollution Reports, 2022)

CRIF1 promotes the progression of non-small-cell lung cancer by SIRT3- mediated deacetylation of PYCR1 - Qi Wang; Zhuolin Xie; Chang Li; Chun Xu; Cheng Ding; Sheng Ju; Jun Chen; Zihan Cui; Chen Chen; Biao Gu; Tengteng Wei; Jun Zhao (Journal of Molecular Histology, 2022)

Association of cognitive impairment and reduced cortical thickness in prefrontal cortex and anterior cingulate cortex with treatment-resistant depression - Mu-Hong Chen; Wan-Chen Chang; Pei-Chi Tu; Wei-Chen Lin; Cheng-Ta Li; Wen-Sheng Huang; Ya-Mei Bai; Shih-Jen Tsai; Tung-Ping Su (Brain Imaging and Behavior, 2022)

Armochaetoglasins J and K: new cytochalasans from Chaetomium globosum - Li Cheng; Xi Zheng; Qin Li; Meng-Sha Wei; Chun-Mei Chen; Hu-Cheng Zhu; Chang-Li Zeng; Xin-Cai Hao; Yong-Hui Zhang (Natural Product Research, 2022)

Nuclear Factor-κB Plays a Positive Role in TNFα Expression in Golden Pompano, Trachinotus ovatus (Linnaeus 1758) - Ke-Cheng Zhu; Hua-Yang Guo; Liang Guo; Bao-Suo Liu; Nan Zhang; Shi-Gui Jiang; Dian-Chang Zhang (Frontiers in Marine Science, 2022)
Tumour necrosis factor-α (TNFα) is a multifarious mediator of lymphoid tissue growth and antimicrobial defence mechanisms, and it acts as a pro-inflammatory regulator. The function of TNFα in parasite infection and the underlying mechanism through which nuclear factor-κB (NF-κB) regulates TNFα remain largely unclear in teleosts. In the present study, TNFα ( ToTNF α) from golden pompano ( Trachinotus ovatus ) was identified, and its sequence features and expression levels were determined. The genomic DNA sequence is composed of 1,130 bp, consists of four exons and three introns, and encodes 341 amino acid polypeptides. The putative protein sequence shares 34.7%–61.9% identity with fish TNFα and possesses a TNF family signature and two conserved cysteine residues. Moreover, the expressions of ToNF- κ B and ToTNF α are constitutively expressed in all examined tissues, with higher levels observed in the immune relevant tissues. Both ToNF- κ B and ToTNF α transcription was increased in the local infection sites (skin and gill) and system immune tissues (liver, spleen and head kidney) after Cryptocaryon irritans stimulation. In addition, to investigate whether ToNF-κB is a regulator of ToTNF α, promoter analysis was performed. The region from -970 to +79 bp is known as the core promoter by different truncated mutants of ToTNF α. Subsequently, the activity of the ToTNF α -p2 promoter was dramatically reduced after targeted mutation of the M6-binding site. Additionally, an electrophoretic mobile shift assay (EMSA) verified that ToNF-κB interacted with the M6-binding site in the ToTNF α promoter region to control the expression of ToTNF α. In conclusion, the present study provides the positive regulation of TNF α transcription by NF-κB and contributes to a better understanding of the transcriptional mechanism of TNF α in fish.

Striatal dopamine synthesis capacity and its association with negative symptoms upon resolution of positive symptoms in first-episode schizophrenia and delusional disorder - Stephanie M. Y. Wong; Y. N. Suen; Charlotte W. C. Wong; Sherry K. W. Chan; Christy L. M. Hui; W. C. Chang; Edwin H. M. Lee; Calvin P. W. Cheng; Garrett C. L. Ho; Gladys Goh Lo; Eric Y. L. Leung; Paul K. M. Au Yeung; et al. (Psychopharmacology, 2022)

Air pollution associated with cognitive decline by the mediating effects of sleep cycle disruption and changes in brain structure in adults - Chen-Chen Lo; Wen-Te Liu; Yueh-Hsun Lu; Dean Wu; Chih-Da Wu; Ting-Chieh Chen; Yu-Ting Fang; Yu-Chun Lo; You-Yin Chen; Lo Kang; Cheng-Yu Tsai; Yueh-Lun Lee; et al. (Environmental Science and Pollution Research, 2022)

The impacts of ambient relative humidity and temperature on supine position-related obstructive sleep apnea in adults - Wen-Te Liu; Yuan-Hung Wang; Li-Te Chang; Chih-Da Wu; Dean Wu; Cheng-Yu Tsai; Chen-Chen Lo; Kang Lo; Kian Fan Chung; Ta-Yuan Chang; Kai-Jen Chuang; Yueh-Lun Lee; et al. (Environmental Science and Pollution Research, 2022)

Brain Reactions to Opening and Closing the Eyes: Salivary Cortisol and Functional Connectivity - Shen-Da Chang; Po-Chih Kuo; Karl Zilles; Tim Q. Duong; Simon B. Eickhoff; Andrew C. W. Huang; Arthur C. Tsai; Philip E. Cheng; Michelle Liou (Brain Topography, 2022)
This study empirically assessed the strength and duration of short-term effects induced by brain reactions to closing/opening the eyes on a few well-known resting-state networks. We also examined the association between these reactions and subjects’ cortisol levels. A total of 55 young adults underwent 8-min resting-state fMRI (rs-fMRI) scans under 4-min eyes-closed and 4-min eyes-open conditions. Saliva samples were collected from 25 of the 55 subjects before and after the fMRI sessions and assayed for cortisol levels. Our empirical results indicate that when the subjects were relaxed with their eyes closed, the effect of opening the eyes on conventional resting-state networks (e.g., default-mode, frontal-parietal, and saliency networks) lasted for roughly 60-s, during which we observed a short-term increase in activity in rs-fMRI time courses. Moreover, brain reactions to opening the eyes had a pronounced effect on time courses in the temporo-parietal lobes and limbic structures, both of which presented a prolonged decrease in activity. After controlling for demographic factors, we observed a significantly positive correlation between pre-scan cortisol levels and connectivity in the limbic structures under both conditions. Under the eyes-closed condition, the temporo-parietal lobes presented significant connectivity to limbic structures and a significantly positive correlation with pre-scan cortisol levels. Future research on rs-fMRI could consider the eyes-closed condition when probing resting-state connectivity and its neuroendocrine correlates, such as cortisol levels. It also appears that abrupt instructions to open the eyes while the subject is resting quietly with eyes closed could be used to probe brain reactivity to aversive stimuli in the ventral hippocampus and other limbic structures.

Quantifying soil nitrous oxide emissions in spring freezing-thawing period over different vegetation types in Northeast China - Bin Wu; Chang-cheng Mu; Hui Liu; Ya-kun Xu; Yue Zhang; Jia-shuo Yang; Wen-nian Xu (Journal of Mountain Science, 2022)

A novel flavonoid with antioxidant activity from Patrinia villosa (Thunb.) Juss - Yang-Cheng Liu; Nan Sui; Jia-Qi Wang; Xin Wang; Wei Liu; Zheng Xiang; Chang-Lan Chen (Natural Product Research, 2022)

Passive Surface-Wave Waveform Inversion for Source-Velocity Joint Imaging - Changjiang Zhou; Jianghai Xia; Feng Cheng; Jingyin Pang; Xinhua Chen; Huaixue Xing; Xiaojun Chang (Surveys in Geophysics, 2022)

Lactobacillus plantarum PS128 Promotes Intestinal Motility, Mucin Production, and Serotonin Signaling in Mice - Chih-Ming Chen; Chien-Chen Wu; Chin-Lin Huang; Min-Yu Chang; Shih-Hsuan Cheng; Ching-Ting Lin; Ying-Chieh Tsai (Probiotics and Antimicrobial Proteins, 2022)
Lactobacillus plantarum PS128 has been reported as a psychobiotic to improve mental health through the gut–brain axis in experimental animal models. To explore its mechanism of action in the gut, this study aimed to analyze the effects of L. plantarum PS128 ingestion on naïve and loperamide (Lop)-induced constipation mice. We found that, in the two mouse models, the weight, number, and water content of feces in the L. plantarum PS128 group were higher than those in the vehicle control group. Histological observation revealed that L. plantarum PS128 increased the level of colonic mucins including the major mucin MUC2. In addition, the charcoal meal test showed that L. plantarum PS128 significantly increased the small intestine transit in naïve mice, but not in the Lop-treated mice. Since intestinal serotonin has been found to modulate motility, we further analyzed the expression of genes related to serotonin signal transduction in the small intestine of naïve mice. The results showed that L. plantarum PS128 significantly altered the expression levels of Tph1 , Chga , Slc6a4 , and Htr4 , but did not affect the expression levels of Tph2 , Htr3a , and Maoa . Furthermore, immunohistochemistry revealed that L. plantarum PS128 significantly increased the number of serotonin-containing intestinal cells in mice. Taken together, our results suggest that L. plantarum PS128 could promote intestinal motility, mucin production, and serotonin signal transduction, leading to a laxative effect in mice.

Using DeepLab v3 + -based semantic segmentation to evaluate platelet activation - Tsung-Chen Kuo; Ting-Wei Cheng; Ching-Kai Lin; Ming-Che Chang; Kuang-Yao Cheng; Yun-Chien Cheng (Medical & Biological Engineering & Computing, 2022)

TREM-2 mediates dendritic cell–induced NO to suppress Th17 activation and ameliorate chronic kidney diseases - Ching-Cheng Lin; Ti-Yung Chang; Yong-Chen Lu; Yun-Syuan Wu; Wei Huang; Wei-Chi Lo; Guan-Fu Liu; Wei-Chan Hsu; Pamela S. Ohashi; Tak W. Mak; Jong-Ling Fuh; Hui-Chen Chen; et al. (Journal of Molecular Medicine, 2022)

Prediction of disability-free survival in healthy older people - Johannes Tobias Neumann; Le T. P. Thao; Anne M. Murray; Emily Callander; Prudence R. Carr; Mark R. Nelson; Rory Wolfe; Robyn L. Woods; Christopher M. Reid; Raj C. Shah; Anne B. Newman; Jeff D. Williamson; et al. (GeroScience, 2022)
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disability-free survival outcome was defined as absence of dementia, persistent disability or death. Selection of potential predictors from amongst 25 biomedical, psychosocial and lifestyle variables including recognized geriatric risk factors, utilizing a machine-learning approach. Separate models were developed for men and women. The selected predictors were evaluated in a multivariable Cox proportional hazards model and validated internally by bootstrapping. We included 19,114 Australian and US participants aged ≥65 years (median 74 years, IQR 71.6–77.7). Common predictors of a worse prognosis in both sexes included higher age, lower Modified Mini-Mental State Examination score, lower gait speed, lower grip strength and abnormal (low or elevated) body mass index. Additional risk factors for men included current smoking, and abnormal eGFR. In women, diabetes and depression were additional predictors. The biased-corrected areas under the receiver operating characteristic curves for the final prognostic models at 5 years were 0.72 for men and 0.75 for women. Final models showed good calibration between the observed and predicted risks. We developed a prediction model in which age, cognitive function and gait speed were the strongest predictors of disability-free survival in healthy older people. Trial registration Clinicaltrials.gov (NCT01038583)

Relationships of multiple metals exposure, global DNA methylation, and urothelial carcinoma in central Taiwan - Hui-Tsung Hsu; Hui-Ling Lee; Hsu-Hui Cheng; Chao-Hsiang Chang; Chiu-Shong Liu; Po-Jen Hsiao; Han Chang; Chi-Shun Lien; Mu-Chi Chung; Chi-Jung Chung (Archives of Toxicology, 2022)

Geographic distance, sedimentation, and substrate shape cryptic crustose coralline algal assemblages in the world’s largest subtropical intertidal algal reef - Shing Hei Zhan; Ling Chen; Chen‐Pan Liao; Wun‐Ruei Chang; Cheng‐Chin Li; Guang‐You Tang; Ching‐Yu Liou; Wei‐Lung Wang; Shih‐Wei Wang; Shao‐Lun Liu (Molecular Ecology, 2022)
Algal reefs, concreted by crustose coralline algae (CCA), are the main biotic reefs in temperate waters but rare in the subtropics and tropics. The world's largest known intertidal algal reef in the subtropics is the Taoyuan Algal Reef (TAR) located in the northwestern coast of Taiwan. The biodiversity and ecology of the TAR are scarcely explored, and now the reef is imperiled by industrialization. Here, we document cryptic species of CCA in Taiwan, particularly the TAR, by sequencing the psb A genes of over 1800 specimens collected across Taiwan. We also examine the ecological background of the TAR by surveying its benthic composition and measuring its environmental parameters. Our data reveal that the TAR harbours a high diversity of cryptic CCA species (27 molecular operational taxonomic units, or mOTUs), many of which are potentially new to science (18 mOTUs) and/or endemic to the TAR (9 mOTUs). Comparing the CCA species inventory of the TAR with the rest of Taiwan shows that the TAR represents a unique hotspot of CCA taxa in the waters of Taiwan. Our analyses show that variation in the CCA assemblages in the TAR is associated with geographic distance, sedimentation, and substrate type (for example, reef vs. hermit crab shell), suggesting that dispersal limitation and contemporary environmental selection shape the CCA assemblages in the TAR. The data from this study can inform the monitoring of human impacts on the health of the TAR and contribute to our understanding of the ecological processes underlying algal reef development.

NURBS-Based Parametric Design for Ship Hull Form - Hui Zhou; Baiwei Feng; Zuyuan Liu; Haichao Chang; Xide Cheng (Journal of Marine Science and Engineering, 2022)
Recently, the NURBS technique has been widely used in the 3D design software for ships. However, in most research, the NURBS technique is only applied to the mathematical representation of hull curves and surfaces, and the parametric deformation of hull surfaces based on geometric feature parameters is less understood. The aims of this paper are to establish the parametric design process of hull surfaces through the classification of geometric feature parameters and the design of feature curves, apply the NURBS technique to the parametric geometric modeling of hull curves and surfaces, and finally achieve the parametric deformation of hull surfaces driven by geometric feature parameters and develop the parametric deformation software. Taking the Series 60 ship as an example, we first analyze the hull geometric features and parameters, then design the longitudinal feature curves and cross-section curves based on the NURBS technique and establish the correlation between them, and finally generate the smooth hull surface by the skinning technique to achieve the parametric geometric deformation of the Series 60 ship. The research in this paper shows that the smoothness of the surfaces generated by the NURBS-based parametric design method is good. Additionally, the extracted feature parameters have a clear geometric meaning and can automatically generate hull forms to meet the design requirements quickly and effectively, which has some practical engineering value.

Interleukin-6 transiently promotes proliferation of osteoclast precursors and stimulates the production of inflammatory mediators - Peng-Yuan Chang; Hung-Kang Wu; Yu-Hsu Chen; Yu-Pao Hsu; Ming-Te Cheng; Ching-Hsiao Yu; Shau-Kwaun Chen (Molecular Biology Reports, 2022)

Isolation and characterization of 112 SNP markers in Yellowfin seabream (Acanthopagrus latus) using RAD sequencing - Ke-Cheng Zhu; Ya-Ling Li; Wei-Bin Wu; Bao-Suo Liu; Hua-Yang Guo; Nan Zhang; Liang Guo; Dian-Chang Zhang (Conservation Genetics Resources, 2022)

Xidaosterols A and B, two new steroids with unusual α -keto-enol functionality from the South China Sea sponge Neopetrosia chaliniformis - Bao Chen; Yu-Cheng Gu; Nicole J. de Voogd; Chang-Yun Wang; Yue-Wei Guo (Natural Product Research, 2022)

Chrysomutanin and related meroterpenoids from a DES mutant of the marine-derived fungus Penicillium chrysogenum S-3-25 - Hua Qiao; Shu-Hua Zhang; Yuan Dong; Yu Yang; Rui Xu; Bo Chen; Yi Wang; Tian-Jiao Zhu; Cheng-Bin Cui; Guo-Gang Zhang; Chang-Wei Li (Natural Product Research, 2022)

Flavonoid components and gene expression analysis reveal flower pigmentation difference between Magnolia biondii and its variety M. biondii var. purpurascens - Ning-hang Wang; Meng-yi Dai; Gang Zheng; Peng-jie Chang; Ling-juan Xuan; Zhi-gao Liu; Ya-ling Wang; Shao-yu Cheng; Zhuo-wei Wang; Hai-long Wang; Cui-hua Gu; Chao Zhang; et al. (Trees, 2022)

The significance of riparian communities in the energy flow of subtropical stream ecosystems - Yi-Chang Liao; An-Cheng Lin; Han-Ni Tsai; Yu-Ting Yen; Chyng-Shyan Tzeng; Man-Miao Yang; Hsing-Juh Lin (Aquatic Sciences, 2022)

Effects of Antrodia camphorata-Supplemented Diets on the Non-Specific Immune Responses and Disease Resistance of Orange-Spotted Grouper (Epinephelus coioides) against Vibrio alginolyticus and Streptococcus iniae - Hsiang-Chieh Chuang; Yin-Ze Shi; Chiu-Min Cheng; Chieh-Yu Pan; Ann-Chang Cheng (Journal of Marine Science and Engineering, 2022)
In Taiwan, the mushroom Antrodia camphorata (AC) is used for medicinal purposes, including cancer prevention and treatment. This study aimed to investigate the effect of AC-supplemented diets on the innate immunity and disease resistance of the orange-spotted grouper Epinephelus coioides against two bacterial infections—Vibrio alginolyticus and Streptococcus iniae. Orange-spotted groupers were fed AC-supplemented diets at 0 (control), 1.5, 3.0, 4.5, and 6.0 g kg−1 for 28 days and examined for innate immune responses and survival rates against V. alginolyticus and S. iniae. The results showed that the innate cellular and humoral immune parameters, including respiratory burst, phagocytic activity, and lysozyme activity of leukocytes, along with serum alternative complement activity (ACH50) and superoxide dismutase activity, as well as interleukin (IL)-4 and IL-6, were all significantly increased in groupers fed AC-supplemented diets. Groupers fed diets containing AC at doses higher than 3.0 g kg−1 had better survival rates than the control group 3–18 days after V. alginolyticus or S. iniae challenge. The enhanced disease resistance may be attributable to AC-induced innate immunity, suggesting that utilizing AC as a dietary supplement at 3.0 g kg−1 may enhance the disease resistance of orange-spotted groupers against Vibrio or Streptococcus infection.

Wave Forces on a Partially Reflecting Wall by Oblique Bragg Scattering with Porous Breakwaters over Uneven Bottoms - Jen-Yi Chang; Chia-Cheng Tsai (Journal of Marine Science and Engineering, 2022)
In this study, the scattering of oblique water waves by multiple variable porous breakwaters near a partially reflecting wall over uneven bottoms are investigated using the eigenfunction matching method (EMM). In the solution procedure, the variable breakwaters and bottom profiles are sliced into shelves separated steps and the solutions on the shelves are composed of eigenfunctions with unknown coefficients representing the wave amplitudes. Using the conservations of mass and momentum as well as the condition for the partially reflecting sidewall, a system of linear equations is resulted that can be solved by a sparse-matrix solver. The proposed EMM is validated by comparing its results with those in the literature. Then, the EMM is applied for studying oblique Bragg scattering by periodic porous breakwaters near a partially reflecting wall over uneven bottoms. The constructive and destructive Bragg scattering are discussed. Numerical results suggest that the partially reflecting wall should be separated from the last breakwater by half wavelength of the periodic breakwaters to migrate the wave force on the vertical wall.

Potential Plasticity of Artificial Feed Preference in Juvenile Pharaoh Cuttlefish (Sepia pharaonis) Through Progressive Training Programs - Chia-Huan Ma; Chih-Hung Lin; Yung-Cheng Chang; Hung-Tai Lee; Chyng-Hwa Liou; Te-Hua Hsu (Frontiers in Marine Science, 2022)
The cuttlefish is a commercially important marine species across the world; however, due to the lack of appropriate artificial feed, there is limited future aquaculture development of the cuttlefish. We proposed a novel process comprising (1) feed preference tests and (2) progressive training programs. Through this process, artificial diets can become more suitable for pharaoh cuttlefish ( Sepia pharaonis ). Feed preference tests (based on vision, touch, and smell) revealed that pharaoh cuttlefish preferred rod-shaped feed to flat rod-shaped or ball-shaped feed, moist feed over dry feed (DF), and DF with agar coating to DF without agar coating. Without olfactory training, some cuttlefish refused to eat artificial feed and eventually died. Through progressive training programs (3- and 6-week programs), a survival rate of >80% was achieved. Although the artificial diets examined in this study resulted in a lower conversion ratio for S. pharaonis than for fresh shrimp, available artificial feed can potentially be adopted for cuttlefish aquaculture through the use of our progressive training program.

Exploring of the spatially varying completeness of a tsunami catalogue - Li X. Ning; Chang X. Cheng; Ana M. Cruz; Emmanuel Garnier (Natural Hazards, 2022)

Adaptation capability of rainfall hotspots in water resilient cities using QGIS: a case study of Taichung City in Taiwan - Ming-jen Cheng; Wei-liang Sia; Feng-chi Liao; Li-shin Chang (Environmental Monitoring and Assessment, 2022)

A comprehensive exploration on the health risk quantification assessment of soil potentially toxic elements from different sources around large-scale smelting area - Chang-Chen Huang; Li-Mei Cai; Yao-Hui Xu; Luo Jie; Lai-Guo Chen; Guo-Cheng Hu; Hui-Hao Jiang; Xu-Bang Xu; Jing-Xian Mei (Environmental Monitoring and Assessment, 2022)

Load transfer laws of tensile anchors in rock masses with weak interlayers based on a shear-slipping updating model - Yan Wang; Xin Xiang; Chang-dong Li; Guo-qiang Zhu; Cheng-bin Song; Jin-ye Xian; Jia-jun Zhang (Journal of Mountain Science, 2022)

Severe introduced predator impacts despite attempted functional eradication - Brian S. Cheng; Jeffrey Blumenthal; Andrew L. Chang; Jordanna Barley; Matthew C. Ferner; Karina J. Nielsen; Gregory M. Ruiz; Chela J. Zabin (Biological Invasions, 2022)

Seasonal to decadal spatiotemporal variations of the global ocean carbon sink - Min Zhang; Yangyan Cheng; Ying Bao; Chang Zhao; Gang Wang; Yuanling Zhang; Zhenya Song; Zhaohua Wu; Fangli Qiao (Global Change Biology, 2022)
The global ocean has absorbed approximately 30% of anthropogenic CO 2 since the beginning of the industrial revolution. However, the spatiotemporal evolution of this important global carbon sink varies substantially on all timescales and has not yet been well evaluated. Here, based on a reconstructed observation‐based product of surface ocean pCO 2 and air–sea CO 2 flux (the MPI‐SOMFFN method), we investigated seasonal to decadal spatiotemporal variations of the ocean CO 2 sink during the past three decades using an adaptive data analysis method. Two predominant variations are modulated annual cycles and decadal fluctuations, which account for approximately 46% and 25% of all extracted components, respectively. Although the whole summer to non‐summer seasonal difference pattern is determined by the Southern Ocean, the non‐summer CO 2 sink at mid‐latitudes in both hemispheres shows an increasing trend (a total increase of approximately 1.0 PgC during the period 1982–2019), while it is relatively stable in summer. On decadal timescales for the global ocean carbon sink, unlike the weakening decade (1990–1999) and the reinvigoration decade (2000–2009) in which the Southern Ocean plays the dominant role, the reinforcement decade (2010–2019) is mainly the result from the weakening source effect in the equatorial Pacific Ocean. Our results suggest that except for the Southern Ocean's role in the global ocean carbon sink, the strengthening non‐summer's sink at mid‐latitudes in both hemispheres and the decadal or longer timescales of equatorial Pacific Ocean dynamics should be fully considered in understanding the oceanic carbon cycle on a global scale.

Sustainable consumption: research on examining the influence of the psychological process of consumer green purchase intention by using a theoretical model of consumer affective events - Tai-Wei Chang; Cheng-Ze Hung (Environment, Development and Sustainability, 2022)

Structure modification, antialgal, antiplasmodial, and toxic evaluations of a series of new marine-derived 14-membered resorcylic acid lactone derivatives - Wei-Feng Xu; Na-Na Wu; Yan-Wei Wu; Yue-Xuan Qi; Mei-Yan Wei; Laura M. Pineda; Michelle G. Ng; Carmenza Spadafora; Ji-Yong Zheng; Ling Lu; Chang-Yun Wang; Yu-Cheng Gu; et al. (Marine Life Science & Technology, 2022)
Marine natural products play critical roles in the chemical defense of many marine organisms and are essential, reputable sources of successful drug leads. Sixty-seven 14-membered resorcylic acid lactone derivatives 3 – 27 and 30 – 71 of the natural product zeaenol ( 1 ) isolated from the marine-derived fungus Cochliobolus lunatus were semisynthesized by chlorination, acylation, esterification, and acetalization in one to three steps. The structures of these new derivatives were established by HRESIMS and NMR techniques. All the compounds ( 1 – 71 ) were evaluated for their antialgal and antiplasmodial activities. Among them, 14 compounds displayed antifouling activities against adhesion of the fouling diatoms. In particular, 9 and 34 exhibited strong and selective inhibitory effects against the diatoms Navicula laevissima and Navicula exigua (EC 50 = 6.67 and 8.55 μmol/L), respectively, which were similar in efficacy to those of the positive control SeaNine 211 (EC 50 = 2.90 and 9.74 μmol/L). More importantly, 38 , 39 , and 69 – 71 showed potent antiplasmodial activities against Plasmodium falciparum with IC 50 values ranging from 3.54 to 9.72 μmol/L. Very interestingly, the five antiplasmodial derivatives displayed non-toxicity in the cytotoxicity assays and the zebrafish embryos model, thus, representing potential promising antiplasmodial drug agents. The preliminary structure–activity relationships indicated that biphenyl substituent at C-2, acetonide at positions C-5′ and C-6′, and tri- or tetra-substituted of acyl groups increased the antiplasmodial activity. Therefore, combining evaluation of chemical ecology with pharmacological models will be implemented as a systematic strategy, not only for environmentally friendly antifoulants but also for structurally novel drugs.

Evolution of research topics on the Tibetan Plateau environment and ecology from 2000 to 2020: a paper mining - Keke Chang; Junyu Tao; Cheng Fang; Jian Li; Wenwu Zhou; Xutong Wang; Beibei Yan; Dan Zeng; Guanyi Chen (Environmental Science and Pollution Research, 2022)

A poly-(L-serine)/reduced graphene oxide–Nafion supported on glassy carbon (PLS/rGO−Nafion/GCE) electrode for the detection of naproxen in aqueous solutions - Chang-Mao Hung; Chin-Pao Huang; Chiu-Wen Chen; Cheng-Di Dong (Environmental Science and Pollution Research, 2022)

Genomic characterization of bacteriophage pSal-SNUABM-01, a novel elongated-head phage infecting Salmonella sp. - Jun Kwon; Sang Guen Kim; Sib Sankar Giri; Hyoun Joong Kim; Sang Wha Kim; Jeong Woo Kang; Sung Bin Lee; Won Jun Jung; Cheng Chi; Se Chang Park (Archives of Virology, 2022)

The Opportunistic Pathogen Chryseobacterium balustinum WLT: Pathogenicity and Antibiotic Resistance - Won Joon Jung; Sang Guen Kim; Sib Sankar Giri; Sang Wha Kim; Jeong Woo Kang; Jun Kwon; Woo Taek Oh; Sung Bin Lee; Young Min Lee; Su Jin Jo; Cheng Chi; Jin Woo Jun; et al. (Fishes, 2022)
This study aimed to re-evaluate the pathogenic characteristics of Chryseobacterium balustinum, generally known as a food spoilage bacterium. We observed mass mortality in a rainbow trout farm in Jeonbuk province, Republic of Korea. Fewer studies have reported on rainbow trout mortality or infections in Korea than in other countries; among these, few studies have reported cases of Chryseobacterium infections. Sequencing analysis revealed that this bacterium is closely related (99.24%) to Chryseobacterium balustinum. Bacterial identification assays, including the API test, sequencing, and phylogenetic analysis, found the 24 isolates to be C. balustinum. The strain showed multiple resistance to 18 of 25 antibiotics tested. Primary clinical symptoms of its infection are damage to the fins, necrosis, and cytoplasmic vacuolation in hepatocytes. The pathogenicity of the strain was determined following Koch’s postulates and the challenge test. The present results suggest that C. balustinum WLT can be considered a multidrug-resistant zoonotic pathogen responsible for mortality and economic losses.

A new N -containing phenolic glycoside from Capsicum annuum L. - Changwei Song; Changyan Yu; Xinting Zhu; Xirong Luo; Yong Zhang; Lingjie Meng; Yong Luo; Han Chang; Cheng Qin; Yun Liu (Natural Product Research, 2022)

Effects of B-azolemiteacrylic on life-history traits and demographic parameters of two-spotted spider mite, Tetranychus urticae (Acari: Tetranychidae) - Suqin Shang; Yun Chang; Wei-Zhen Li; Wang Chang-Qing; Nie Peng-Cheng (Experimental and Applied Acarology, 2022)
The present study was conducted to evaluate sublethal effects of B-azolemiteacrylic on the two-spotted spider mite, Tetranychus urticae Koch (Acari: Tetranychidae). Female adults of T. urticae were exposed to LC 10 and LC 30 of the acaricide, and the effects on treated females and their offspring were evaluated. The results showed that the fecundity of F 0 female adults treated with LC 10 and LC 30 of B-azolemiteacrylic was reduced by 30.9 and 39.2%, respectively. Longevity and oviposition period of the females were significantly reduced as well. The developmental duration of egg and deutonymph stage of the F 1 generation were not significantly different from that of the control. The protonymph stage after LC 30 treatment lasted significantly longer, whereas the larva, deutonymph and female stage were significantly shorter than the control. The oviposition period of the F 1 generation was significantly shortened, the fecundity of each female decreased significantly, and the ratio of female-to-male was reduced too. Moreover, the average generation period of T. urticae after LC 10 and LC 30 treatments was shorter than that of the control, and the net production rate ( R 0 ), intrinsic rate of increase ( r m ) and finite rate of increase ( λ ) were all reduced by 33.3, 7.5 and 1.9% (LC 10 treatment) and by 51.3, 14.8 and 3.6% (LC 30 treatment), respectively. The population doubling time was prolonged by 7.5 and 14.8% after LC 10 and LC 30 treatments, respectively, compared with the control. These results indicate that B-azolemiteacrylic may effectively inhibit the development rate of the F 0 and F 1 populations of T. urticae , which will help design integrated strategies for the comprehensive control of T. urticae and rational use of pesticides in the field.

Associations between lung-deposited dose of particulate matter and culture-positive pulmonary tuberculosis pleurisy - Kuan-Jen Bai; Nguyen Thanh Tung; Ta-Chih Hsiao; Tsai-Ling Chen; Kian Fan Chung; Shu-Chuan Ho; Cheng-Yu Tsai; Jen-Kun Chen; Chun-Nin Lee; Kang-Yun Lee; Chih-Cheng Chang; Tzu-Tao Chen; et al. (Environmental Science and Pollution Research, 2022)

Antibiotic resistance genes on the Qinghai-Tibet Plateau above an elevation of 5,000 m - Xiaomin Wang; Chang Han; Bangrui Lan; Cheng Wang; Guibing Zhu (Environmental Science and Pollution Research, 2022)

Six-DOF CFD Simulations of Underwater Vehicle Operating Underwater Turning Maneuvers - Kunyu Han; Xide Cheng; Zuyuan Liu; Chenran Huang; Haichao Chang; Jianxi Yao; Kangli Tan (Journal of Marine Science and Engineering, 2021)
Maneuverability, which is closely related to operational performance and safety, is one of the important hydrodynamic properties of an underwater vehicle (UV), and its accurate prediction is essential for preliminary design. The purpose of this study is to analyze the turning ability of a UV while rising or submerging; the computational fluid dynamics (CFD) method was used to numerically predict the six-DOF self-propelled maneuvers of submarine model BB2, including steady turning maneuvers and space spiral maneuvers. In this study, the overset mesh method was used to deal with multi-body motion, the body force method was used to describe the thrust distribution of the propeller at the model scale, and the numerical prediction also included the dynamic deflection of the control planes, where the command was issued by the autopilot. Then, this study used the published model test results of the tank to verify the effectiveness of the CFD prediction of steady turning maneuvers, and the prediction of space spiral maneuvers was carried out on this basis. The numerical results show that the turning motion has a great influence on the depth and pitch attitude of the submarine, and a “stern heavier” phenomenon occurs to a submarine after steering. The underwater turning of a submarine can not only reduce the speed to brake but also limit the dangerous depth. The conclusion is of certain reference significance for submarine emergency maneuvers.

DAGDU: center location of tropical cyclones using Deviation Angle Gradient Distribution Uniformity from infrared satellite images - Chang-Jiang Zhang; Xiao-Jie Wang; Li-Cheng Xue (International Journal of Remote Sensing, 2021)

Increasing nitrogen supply to phosphorus-deficient Medicago sativa decreases shoot growth and enhances root exudation of tartrate to discharge surplus carbon dependent on nitrogen form - Honghua He; Zekun Zhang; Qi Peng; Chao Chang; Rui Su; Xiao Cheng; Yingxin Li; Jiayin Pang; Sheng Du; Hans Lambers (Plant and Soil, 2021)

Correction to: μ-Opioid Receptor–Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation - Hui Gao; Yuxin Zhang; Yansong Li; Haiqing Chang; Bo Cheng; Na Li; Wei Yuan; Shuang Li; Qiang Wang (Molecular Neurobiology, 2021)

Electrical Impedance Tomography Analysis Between Two Similar Respiratory System Compliance During Decremetal PEEP Titration in ARDS Patients - Po-Lan Su; Wei-Chieh Lin; Yen-Fen Ko; Kuo-Sung Cheng; Chang-Wen Chen (Journal of Medical and Biological Engineering, 2021)
Purpose The positive end-expiratory pressure (PEEP) level with best respiratory system compliance (Crs) is frequently used for PEEP selection in acute respiratory distress syndrome (ARDS) patients. On occasion, two similar best Crs (where the difference between the Crs of two PEEP levels is < 1 ml/cm H 2 O) may be identified during decremental PEEP titration. Selecting PEEP under such conditions is challenging. The aim of this study was to provide supplementary rationale for PEEP selection by assessing the global and regional ventilation distributions between two PEEP levels in this situation. Methods Eight ARDS cases with similar best Crs at two different PEEP levels were analyzed using examination-specific electrical impedance tomography (EIT) measures and airway stress index (SIaw). Five Crs were measured at PEEP values of 25 cm H 2 O (PEEP 25 ), 20 cm H 2 O (PEEP 20 ), 15 cm H 2 O (PEEP H ), 11 cm H 2 O (PEEP I ), and 7 cm H 2 O (PEEP L ). The higher PEEP value of the two PEEPs with similar best Crs was designated as PEEP upper , while the lower designated as PEEP lower . Results PEEP H and PEEP I shared the best Crs in two cases, while similar Crs was found at PEEP I and PEEP L in the remaining six cases. SIaw was higher with PEEP upper as compared to PEEP lower (1.06 ± 0.10 versus 0.99 ± 0.09, p = 0.05). Proportion of lung hyperdistension was significantly higher with PEEP upper than PEEP lower (7.0 ± 5.1% versus 0.3 ± 0.5%, p = 0.0002). In contrast, proportion of recruitable lung collapse was higher with PEEP lower than PEEP upper (18.6 ± 4.4% versus 5.9 ± 3.7%, p < 0.0001). Cyclic alveolar collapse and reopening during tidal breathing was higher at PEEP lower than PEEP upper (34.4 ± 19.3% versus 16.0 ± 9.1%, p = 0.046). The intratidal gas distribution (ITV) index was also significantly higher at PEEP lower than PEEP upper (2.6 ± 1.3 versus 1.8 ± 0.7, p = 0.042). Conclusions PEEP upper is a rational selection in ARDS cases with two similar best Crs. EIT provides additional information for the selection of PEEP in such circumstances.

Application of thermal desorption for measuring PAHs on PM2.5 - Yuan Cheng Hsu; Yen Chen Hsu; Moo Been Chang (Environmental Science and Pollution Research, 2021)

Global gross nitrification rates are dominantly driven by soil carbon‐to‐nitrogen stoichiometry and total nitrogen - Ahmed S. Elrys; Jing Wang; Mohamed A. S. Metwally; Yi Cheng; Jin‐Bo Zhang; Zu‐Cong Cai; Scott X. Chang; Christoph Müller (Global Change Biology, 2021)
Soil gross nitrification (GN) is a critical process in the global nitrogen (N) cycle that results in the formation of nitrate through microbial oxidation of ammonium or organic N, and can both increase N availability to plants and nitrous oxide emissions. Soil GN is thought to be mainly controlled by soil characteristics and the climate, but a comprehensive analysis taking into account the climate, soil characteristics, including microbial characteristics, and their interactions to better understand the direct and indirect controlling factors of GN rates globally is lacking. Using a global meta‐analysis based on 901 observations from 330 15 N‐labeled studies, we show that GN differs significantly among ecosystem types, with the highest rates found in croplands, in association with higher pH which stimulates nitrifying bacteria activities. Autotrophic and heterotrophic nitrifications contribute 63% and 37%, respectively, to global GN. Soil GN increases significantly with soil total N, microbial biomass, and soil pH, but decreases significantly with soil carbon (C) to N ratio (C:N). Structural equation modeling suggested that GN is mainly controlled by C:N and soil total N. Microbial biomass and pH are also important factors controlling GN and their effects are similar. Precipitation and temperature affect GN by altering C:N and/or soil total N. Soil total N and temperature drive heterotrophic nitrification, whereas C:N and pH drive autotrophic nitrification. Moreover, GN is positively related to nitrous oxide and carbon dioxide emissions. This synthesis suggests that changes in soil C:N, soil total N, microbial population size, and/or soil pH due to anthropogenic activities may influence GN, which will affect nitrate accumulation and gaseous emissions of soils under global climate and land‐use changes.

A Unique Diel Pattern in Carbonate Chemistry in the Seagrass Meadows of Dongsha Island: The Enhancement of Metabolic Carbonate Dissolution in a Semienclosed Lagoon - Wen-Chen Chou; Lan-Feng Fan; Chang-Chang Yang; Ying-Hsuan Chen; Chin-Chang Hung; Wei-Jen Huang; Yung-Yen Shih; Keryea Soong; Hsiao-Chun Tseng; Gwo-Ching Gong; Hung-Yu Chen; Cheng-Kuan Su (Frontiers in Marine Science, 2021)
In contrast to other seagrass meadows where seawater carbonate chemistry generally shows strong diel variations with higher pH but lower partial pressure of CO 2 ( p CO 2 ) during the daytime and lower pH but higher p CO 2 during nighttime due to the alternation in photosynthesis and respiration, the seagrass meadows of the inner lagoon (IL) on Dongsha Island had a unique diel pattern with extremely high pH and low p CO 2 across a diel cycle. We suggest that this distinct diel pattern in pH and p CO 2 could be associated with the enhancement of total alkalinity (TA) production coupled to carbonate sediment dissolution in a semienclosed lagoon. The confinement of the IL may hamper water exchange and seagrass detritus export to the adjacent open ocean, which may result in higher organic matter loading to the sediments, and longer residence time of the water in the IL, accompanied by microbial respiration (both aerobic and anaerobic) that may reduce carbonate saturation level to drive carbonate dissolution and thus TA elevation, thereby forming such a unique diel pattern in carbonate chemistry. This finding further highlights the importance of considering TA production through metabolic carbonate dissolution when evaluating the potential of coastal blue carbon ecosystems to buffer ocean acidification and to absorb atmospheric CO 2 , in particular in a semienclosed setting.

Cytotoxic triterpenoid glycosides from leaves of Cyclocarya paliurus - Hui-Hui Sun; Wen-Yan Lv; Jie Tan; Yu-Cheng Tang; Hui Zhu; Jian-Bo Qu; Jing Li; Jian-Ping Wu; Xi-Wen Chang; Zhi-Chun Yang; Wen-Xuan Wang; Zu-Hui Chen; et al. (Natural Product Research, 2021)

RETRACTED ARTICLE: Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine Sulfate - Chang Ren; Yao Wang; Mei Zhang; Dexuan Kong; Chen Ning; Yujie Cheng; Yueying Bian; Mengqi Sun; Shengdi Su; Yucong Wang; Yongjie Zhang; Yang Lu; et al. (Pharmaceutical Research, 2021)

The intriguing chemistry and biology of sulfur-containing natural products from marine microorganisms (1987–2020) - Yang Hai; Mei-Yan Wei; Chang-Yun Wang; Yu-Cheng Gu; Chang-Lun Shao (Marine Life Science & Technology, 2021)
Natural products derived from marine microorganisms have received great attention as a potential resource of new compound entities for drug discovery. The unique marine environment brings us a large group of sulfur-containing natural products with abundant biological functionality including antitumor, antibiotic, anti-inflammatory and antiviral activities. We reviewed all the 484 sulfur-containing natural products (non-sulfated) isolated from marine microorganisms, of which 59.9% are thioethers, 29.8% are thiazole/thiazoline-containing compounds and 10.3% are sulfoxides, sulfones, thioesters and many others. A selection of 133 compounds was further discussed on their structure–activity relationships, mechanisms of action, biosynthesis, and druggability. This is the first systematic review on sulfur-containing natural products from marine microorganisms conducted from January 1987, when the first one was reported, to December 2020.

Transformation of bisphenol AF by chlorination: kinetic study and product identification - Jingyi Chang; Wenrui Xiang; Ruijuan Qu; Cheng Sun; Zunyao Wang; Feng Zhu; Zongli Huo (Environmental Science and Pollution Research, 2021)

Impact of rhizosphere microorganisms on arsenic (As) transformation and accumulation in a traditional Chinese medical plant - Jiao-Jiao Li; Long Yang; Cui-Ping Miao; Ya-Jun Teng; Zi-Hao Fu; Chang-Lei Cheng; Xue-Xiu Chang; Yu Qian; Li-Xing Zhao (Environmental Science and Pollution Research, 2021)

Differential metabolism-associated gene expression of duck pancreatic cells in response to two strains of duck hepatitis A virus type 1 - Zhen Chen; Shao-hua Shi; Yu Huang; Cui-qin Huang; Rong-chang Liu; Long-fei Cheng; Guang-hua Fu; Hong-mei Chen; Chun-he Wan; Qiu-ling Fu (Archives of Virology, 2021)
Several outbreaks of duck hepatitis A virus type 1 (DHAV-1), which were characterized by yellow coloration and hemorrhage in pancreatic tissues, have occurred in China. The causative agent is called pancreatitis-associated DHAV-1. The mechanisms involved in pancreatitis-associated DHAV-1 infection are still unclear. Transcriptome analysis of duck pancreas infected with classical-type DHAV-1 and pancreatitis-associated DHAV-1 was carried out. Deep sequencing with Illumina-Solexa resulted in a total of 53.9 Gb of clean data from the cDNA library of the pancreas, and a total of 29,597 unigenes with an average length of 993.43 bp were generated by de novo sequence assembly. The expression levels of D-3-phosphoglycerate dehydrogenase, phosphoserine aminotransferase, and phosphoserine phosphatase, which are involved in glycine, serine, and threonine metabolism pathways, were significantly downregulated in ducks infected with pancreatitis-associated DHAV-1 compared with those infected with classical-type DHAV-1. These findings provide information regarding differences in expression levels of metabolism-associated genes between ducks infected with pancreatitis-associated DHAV-1 and those infected with classical-type DHAV-1, indicating that intensive metabolism disorders may contribute to the different phenotypes of DHAV-1-infection.

Patterns and drivers of global gross nitrogen mineralization in soils - Ahmed S. Elrys; Ahmad Ali; Huimin Zhang; Yi Cheng; Jinbo Zhang; Zu‐Cong Cai; Christoph Müller; Scott X. Chang (Global Change Biology, 2021)
Soil gross nitrogen (N) mineralization (GNM), a key microbial process in the global N cycle, is mainly controlled by climate and soil properties. This study provides for the first time a comprehensive analysis of the role of soil physicochemical properties and climate and their interactions with soil microbial biomass (MB) in controlling GNM globally. Through a meta‐analysis of 970 observations from 337 published papers from various ecosystems, we found that GNM was positively correlated with MB, total carbon, total N and precipitation, and negatively correlated with bulk density (BD) and soil pH. Our multivariate analysis and structural equation modeling revealed that GNM is driven by MB and dominantly influenced by BD and precipitation. The higher total N accelerates GNM via increasing MB. The decrease in BD stimulates GNM via increasing total N and MB, whereas higher precipitation stimulates GNM via increasing total N. Moreover, the GNM varies with ecosystem type, being greater in forests and grasslands with high total carbon and MB contents and low BD and pH compared to croplands. The highest GNM was observed in tropical wet soils that receive high precipitation, which increases the supply of soil substrate (total N) to microbes. Our findings suggest that anthropogenic activities that affect soil microbial population size, BD, soil substrate availability, or soil pH may interact with changes in precipitation regime and land use to influence GNM, which may ultimately affect ecosystem productivity and N loss to the environment.

Vertical Nitrate Flux Induced by Kelvin–Helmholtz Billows Over a Seamount in the Kuroshio - Cristy S. Acabado; Yu-Hsin Cheng; Ming-Huei Chang; Chung-Chi Chen (Frontiers in Marine Science, 2021)
Kelvin–Helmholtz (KH) billows can facilitate microscale turbulent mixing around seamounts in the Kuroshio. This study sought to describe the influence of billow intensity (i.e., “intermittent and small” and “steady and large” billows) on vertical nitrate fluxes. KH billows led to turbulent kinetic energy dissipation rates [ε = O (10 –7 to 10 –6 ) W kg –1 ] and eddy diffusivities [K ρ = O (10 –4 to 10 –3 ) m 2 s –1 ] that were significantly stronger than those outside the billow depths. The mean nitrate flux estimated using K ρ in the billow depths had a maximal value of 10.0 mmol m –2 day –1 , which was much higher than estimates for the open ocean. The nitrate flux associated with the shallow KH billows at two vertical levels contributed to enrich the subsurface phytoplankton maximum, while the deeper billows closer to the summit were found to induce a large amount of nitrate flux from the deeper to the subsurface water. This study showed that KH billows make important contributions to seamount ecosystems, particularly in the cycling and vertical mixing of nutrients to make them available for potential downstream transport.

Comparison of Primary Production Using in situ and Satellite-Derived Values at the SEATS Station in the South China Sea - Yung-Yen Shih; Fuh-Kwo Shiah; Chao-Chen Lai; Wen-Chen Chou; Jen-Hua Tai; Yu-Shun Wu; Cheng-Yang Lai; Chia-Ying Ko; Chin-Chang Hung (Frontiers in Marine Science, 2021)
Satellite-based observations of primary production (PP) are broadly used to assess carbon fixation rate of phytoplankton in the global ocean with small spatiotemporal limitations. However, the remote sensing can only reach the ocean surface, the assumption of a PP vertically exponential decrease with increasing depth from the surface to the bottom of euphotic zone may cause a substantial and potential discrepancy between in situ measurements and satellite-based observations of PP. This study compared euphotic zone integrated PP derived from measurements based on ship-based in situ incubation (i.e., PP in situ ) and those derived from the satellite-based vertically generalized production model (VGPM; PP VGPM ) for the period 2003∼2016 at the South East Asian Time-series Study (SEATS) station. PP values obtained during the NE-monsoon (NEM: Nov∼Mar; PP in situ = 323 ± 134; PP VGPM = 443 ± 142 mg-C m –2 d –1 ) were ∼2-fold higher than those recorded during the SW-monsoon (SWM: Apr∼Oct; PP in situ = 159 ± 58; PP VGPM = 250 ± 36 mg-C m –2 d –1 ), regardless of the method used for derivation. The main reason for the higher PP values during the NEM appears to have been a greater abundance of inorganic nutrients were made available by vertical advection. Note that on average, PP in situ estimates were ∼50% lower than PP VGPM estimates, regardless of the monsoon. These discrepancies can be mainly attributed to differences from the euphotic zone depth between satellite-based and in situ measurements. The significantly negative relationship between PP measurements obtained in situ and sea surface temperatures observed throughout this study demonstrates that both methods are effective indicators in estimating PP. Overall, our PP in situ analysis indicates that a warming climate is unfavorable for primary production in low-latitude open ocean ecosystems.

Overexpression of HOTAIR attenuates Pi-induced vascular calcification by inhibiting Wnt/β-catenin through regulating miR-126/Klotho/SIRT1 axis - Yan Chen; Chong Huang; Shu-Ying Zhu; Hong-Chang Zou; Cheng-Yun Xu; Yan-Xia Chen (Molecular and Cellular Biochemistry, 2021)

Distinct population histories among three unique species of oceanic skaters Halobates Eschscholtz, 1822 (Hemiptera: Heteroptera: Gerridae) in the Eastern Pacific Ocean - Wendy Y. Wang; Jia Jin Marc Chang; Richard Norris; Danwei Huang; Lanna Cheng (Marine Biology, 2021)

Correction to: Organic matter degradation state affects dissimilatory nitrate reduction processes in Knysna estuarine sediment, South Africa - Yongkai Chang; Lijun Hou; Dengzhou Gao; Min Liu; Cheng Liu; Zongxiao Zhang (Journal of Soils and Sediments, 2021)

Nitrogen removal processes coupled with nitrification in coastal sediments off the north East China Sea - Yongkai Chang; Guoyu Yin; Lijun Hou; Min Liu; Yanling Zheng; Ping Han; Hongpo Dong; Xia Liang; Dengzhou Gao; Cheng Liu (Journal of Soils and Sediments, 2021)

Organic matter degradation state affects dissimilatory nitrate reduction processes in Knysna estuarine sediment, South Africa - Yongkai Chang; Lijun Hou; Dengzhou Gao; Min Liu; Cheng Liu; Zongxiao Zhang (Journal of Soils and Sediments, 2021)

Application of Basis Functions for Hull Form Surface Modification - Baiwei Feng; Chengsheng Zhan; Zuyuan Liu; Xide Cheng; Haichao Chang (Journal of Marine Science and Engineering, 2021)
Basis functions are key in constructing interpolation equations in hull surface modification based on radial basis functions (RBF) interpolation. However, few have studied the selection of basis functions in depth. By comparing several typical basis functions through a theoretical analysis and two-dimensional modification examples, the Wendland ψ3,1 (W) function is selected. The advantages of hull form surface modification based on W function interpolation are further validated through a case study. Finally, the modification method is used to optimize a trimaran model. An optimal hull form with fair lines is obtained, and its wave-making resistance coefficient and total resistance are reduced by 8.3% and 3.8%, respectively, compared to those of the original model. These findings not only further illustrate that the W function is relatively suitable for hull form surface modification, but also validate the feasibility and value of the RBF interpolation-based surface modification method in engineering practice.

Numerical Study on the Hydrodynamic Characteristics of a Double-Row Floating Breakwater Composed of a Pontoon and an Airbag - Xiaofei Cheng; Chang Liu; Qilong Zhang; Ming He; Xifeng Gao (Journal of Marine Science and Engineering, 2021)
By adding a cylindrical airbag on the leeward side of a cuboid pontoon, a new-type double-row floating breakwater is designed to improve the wave attenuation performance, and its hydrodynamic characteristics are studied through numerical simulations. First, based on the smoothed particle hydrodynamics (SPH) method, a numerical model used to simulate the interaction between waves and moored floating bodies is built. The fluid motion is governed by the Navier–Stokes equations. The motion of the floating body is computed according to Newton’s second law. The modified dynamic boundary condition is employed to treat the solid boundary. The lumped-mass method is adopted to implement the mooring system. Then, two physical model experiments on waves interaction with cuboid and dual cylindrical floating pontoons are reproduced. By comparing the experimental and numerical wave transmission coefficients, wave reflection coefficients, response amplitude operators and mooring force, the reliability of the numerical model is validated. Finally, the validated numerical model is applied to study the influence of separation distance and wave parameters on the hydrodynamic characteristics of the double-row floating breakwater. The results indicate that the optimal separation distance between pontoon and airbag is 0.75 times the wavelength. At such separation distance and within the concerned 1–4 m wave heights and 4–7 s wave periods, the pontoon-airbag system presents better wave attenuation performance than a single pontoon. This improvement weakens as wave height increases while it strengthens as the wave period increases. In addition, the double-row floating breakwater is more effective in a high-wave regime than in a low-wave regime. In the case of short waves, attention should be paid to the stability and mooring reliability of the seaward pontoon, while in the case of long waves, care needs to be taken of the leeward airbag.

Information Matrix-Based Adaptive Sampling in Hull Form Optimisation - Xuyu Ouyang; Haichao Chang; Baiwei Feng; Zuyuan Liu; Chengsheng Zhan; Xide Cheng (Journal of Marine Science and Engineering, 2021)
Hull form optimisation involves challenges such as large design spaces, numerous design variables, and high nonlinearity. Therefore, optimisation that only use global approximate models alone cannot yield desirable results. An information matrix-based method is proposed for dynamically embedded local approximate models (IM-DEAM) in this paper, which uses the Gaussian-function information matrix to extract one or more subspaces for additional sampling and a Latin hypercube design (LHD) for adaptive sampling. In addition, to prevent overfitting by global approximate models in some spaces because of the uneven distribution of the samples, local approximate models are embedded in the subspaces identified for additional sampling to enable accurate description of subspaces. The effectiveness and robustness of the method are validated and analysed by applying the proposed method to optimise mathematical functions and the hull form of the DTMB 5415. The results demonstrate that the proposed method is effective for improving the accuracies and can produce reliable optimisation results.

Applying Artificial Intelligence (AI) Techniques to Implement a Practical Smart Cage Aquaculture Management System - Chung-Cheng Chang; Jung-Hua Wang; Jenq-Lang Wu; Yi-Zeng Hsieh; Tzong-Dar Wu; Shyi-Chy Cheng; Chin-Chun Chang; Jih-Gau Juang; Chyng-Hwa Liou; Te-Hua Hsu; Yii-Shing Huang; Cheng-Ting Huang; et al. (Journal of Medical and Biological Engineering, 2021)
Purpose This paper presents our team’s results to establish an AIoT smart cage culture management system. Methods According to the built system, the farmed field information is transmitted to the data platform of Ocean Cloud, and all collected data and analysis results can be applied to the cage culture field after the bigdata analysis. Results This management system successfully integrates AI and IoT technologies and is applied in cage culture. Using underwater biological analysis images and AI feeding as examples, this paper explains how the system integrates AI and IoT into a feasible framework that can constantly acquire information about the health status of fish, survival rate of fish, as well as the feed residuals. Conclusion The results of our research enable the aquaculture operators or owners to efficiently reduce the feed residual, monitor the growth of fish, and increase fish survival rate, thereby increasing the feed conversion rate.

Thinner Sea Ice Contribution to the Remarkable Polynya Formation North of Greenland in August 2018 - Xiaoyi Shen; Chang-Qing Ke; Bin Cheng; Wentao Xia; Mengmeng Li; Xuening Yu; Haili Li (Advances in Atmospheric Sciences, 2021)
In August 2018, a remarkable polynya was observed off the north coast of Greenland, a perennial ice zone where thick sea ice cover persists. In order to investigate the formation process of this polynya, satellite observations, a coupled ice-ocean model, ocean profiling data, and atmosphere reanalysis data were applied. We found that the thinnest sea ice cover in August since 1978 (mean value of 1.1 m, compared to the average value of 2.8 m during 1978−2017) and the modest southerly wind caused by a positive North Atlantic Oscillation (mean value of 0.82, compared to the climatological value of −0.02) were responsible for the formation and maintenance of this polynya. The opening mechanism of this polynya differs from the one formed in February 2018 in the same area caused by persistent anomalously high wind. Sea ice drift patterns have become more responsive to the atmospheric forcing due to thinning of sea ice cover in this region.

The major photoprotective role of anthocyanins in leaves of Arabidopsis thaliana under long-term high light treatment: antioxidant or light attenuator? - Xiao-Ting Zheng; Zheng-Chao Yu; Jun-Wei Tang; Min-Ling Cai; Yi-Lin Chen; Cheng-Wei Yang; Wah Soon Chow; Chang-Lian Peng (Photosynthesis Research, 2021)

Mediation Effect of Health Beliefs in the Relationship Between Health Knowledge and Uptake of Mammography in a National Breast Cancer Screening Program in Taiwan - Hui-Min Hsieh; Wei-Chieh Chang; Cheng-Ting Shen; Yi Liu; Fang-Ming Chen; Ya-Ting Kang (Journal of Cancer Education, 2021)

μ-Opioid Receptor–Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation - Hui Gao; Yuxin Zhang; Yansong Li; Haiqing Chang; Bo Cheng; Na Li; Wei Yuan; Shuang Li; Qiang Wang (Molecular Neurobiology, 2021)

Characterization Of Secondary Metabolites From The Rhizome Of Cynara Scolymus And Their Antioxidant Properties - Chia-Lin Lee; Kuo-Chen Liao; Chien-Chih Chen; Yen-An Lin; Tung-Ying Wu; Yun-Lian Jhan; Chao-Jung Chen; Juan-Cheng Yang; Yang-Chang Wu (Natural Product Research, 2021)

Step Approximation for Water Wave Scattering by Multiple Thin Barriers over Undulated Bottoms - Chang-Thi Tran; Jen-Yi Chang; Chia-Cheng Tsai (Journal of Marine Science and Engineering, 2021)
This paper investigates the scattering of oblique water waves by multiple thin barriers over undulation bottoms using the eigenfunction matching method (EMM). In the solution procedures of the EMM, the bottom topographies are sliced into shelves separated by steps. On each step, surface-piercing or/and bottom-standing barriers can be presented or not. For each shelf, the solution is composed of eigenfunctions with unknown coefficients representing the wave amplitudes. Then applying the conservations of mass and momentum, a system of linear equations is resulted and can be solved by a sparse-matrix solver. If no barriers are presented on the steps, the proposed EMM formulation degenerates to the water wave scattering over undulating bottoms. The effects on the barrier lengths, barrier positions and oblique wave incidences by different undulated bottoms are studied. In addition, the EMM is also applied to solve the Bragg reflections of normal and oblique water waves by periodic barrier over sinusoidal bottoms. The accuracy of the solution is demonstrated by comparing it with the results in the literature.

Using the Metabolome to Understand the Mechanisms Linking Chronic Arsenic Exposure to Microglia Activation, and Learning and Memory Impairment - Rui-Yuan Zhang; Jie-Bai Tu; Rui-Tu Ran; Wen-Xuan Zhang; Qiang Tan; Ping Tang; Tao Kuang; Shu-Qun Cheng; Cheng-Zhi Chen; Xue-Jun Jiang; Chang Chen; Ting-Li Han; et al. (Neurotoxicity Research, 2021)

Identification and functional characterization of a PDR transporter in Tripterygium wilfordii Hook.f. that mediates the efflux of triptolide - Guopeng Miao; Juan Han; Yan-bo Huo; Cheng-run Wang; Shun-chang Wang (Plant Molecular Biology, 2021)

Fibroblast Growth Factor 9 Stimulates Neuronal Length Through NF-kB Signaling in Striatal Cell Huntington’s Disease Models - Issa Olakunle Yusuf; Hsiu-Mei Chen; Pei-Hsun Cheng; Chih-Yi Chang; Shaw-Jenq Tsai; Jih-Ing Chuang; Chia-Ching Wu; Bu-Miin Huang; H. Sunny Sun; Chuan-Mu Chen; Shang-Hsun Yang (Molecular Neurobiology, 2021)

First report of cucurbit chlorotic yellows virus infecting melon, watermelon and wild melon in the Philippines - Hsin-Yi Chang; Li-Cheng Chen; Chung-Cheng Lin; Wen-Shi Tsai (Journal of Plant Pathology, 2021)

Effects of oxytetracycline on plant growth, phosphorus uptake, and carboxylates in the rhizosheath of alfalfa - Zekun Zhang; Rui Su; Chao Chang; Xiao Cheng; Qi Peng; Hans Lambers; Honghua He (Plant and Soil, 2021)

Dietary berberine can ameliorate glucose metabolism disorder of Megalobrama amblycephala exposed to a high-carbohydrate diet - Chang He; Xiaoyan Jia; Li Zhang; Fan Gao; Weibo Jiang; Chuang Wen; Cheng Chi; Xiangfei Li; Guangzhen Jiang; Haifeng Mi; Wenbin Liu; Dingdong Zhang (Fish Physiology and Biochemistry, 2021)

Mechanism of colluvial landslide induction by rainfall and slope construction: A case study - Zhou Zhou; Jun-hui Shen; Ying Li; Wei-feng Duan; Ri-chang Yang; Jun-cheng Shu; He-wei Li; Sheng-yu Tao; Sheng-zhe Zheng (Journal of Mountain Science, 2021)

Carbon monoxide-triggered health effects: the important role of the inflammasome and its possible crosstalk with autophagy and exosomes - Rong-Jane Chen; Yu-Hsuan Lee; Tzu-Hao Chen; Yu-Ying Chen; Ya-Ling Yeh; Ching-Ping Chang; Chien-Cheng Huang; How-Ran Guo; Ying-Jan Wang (Archives of Toxicology, 2021)

Investigation of the Arctic Sea ice volume from 2002 to 2018 using multi‐source data - Mengmeng Li; Chang‐Qing Ke; Xiaoyi Shen; Bin Cheng; Haili Li (International Journal of Climatology, 2021)
The Arctic sea ice volume (SIV) was investigated by applying sea ice concentration (SIC) and multi‐source sea ice thickness (SIT) products from the Pan‐Arctic Ice‐Ocean Modelling and Assimilation System (PIOMAS), Envisat and CryoSat‐2 (CS‐2) products. The SIV was estimated during the sea ice growth season (October–April) from October 2002 to December 2018. During the Envisat period (October 2002–April 2010), negative SIV trends were estimated by a hybrid Envisat and PIOMAS SIT dataset (defined as Envi‐PIO); the declining trends for both the maximum/minimum SIV were 360 and 177 km 3 ⋅year −1 , respectively; similar SIV trends were obtained by applying only the PIOMAS SIT data. During the CS‐2 period (October 2010–December 2018), no clear trends in the SIV were estimated by either CS‐2 or PIOMAS, except for clear increases in the SIV in northern Greenland and the Canadian Arctic Archipelago (CAA) using the CS‐2 SIT data. The age of sea ice plays an important role in SIV variability. For example, the SIV trend was found to be similar to the multi‐year ice trend between 2003 and 2007. The correlation coefficients between the monthly mean SIV and surface air temperature (SAT) and sea surface temperature (SST) were −0.60 and −0.82, respectively. The decreasing trend in the SIV during the Envisat period was influenced by the increase in the annual maximum SST and minimum SAT. The significant increase in the SIV in northern Greenland and the CAA during the CS‐2 period was related to ice deformation.

Salinity and nutrient modulate soil bacterial communities in the coastal wetland of the Yellow River Delta, China - Qingli Cheng; Huiping Chang; Xue Yang; Ding Wang; Wenlin Wang (Environmental Science and Pollution Research, 2021)

Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis - Tsung-Ying Tsai; Li-Wei Lo; Shin-Huei Liu; Wen-Han Cheng; Yu-Hui Chou; Wei-Lun Lin; Yenn-Jiang Lin; Shih-Lin Chang; Yu-Feng Hu; Fa-Po Chung; Jo-Nan Liao; Tze-Fan Chao; et al. (Environmental Science and Pollution Research, 2021)

Corrigendum: Quantifying Coral Reef Resilience to Climate Change and Human Development: An Evaluation of Multiple Empirical Frameworks - Ashley H. Y. Bang; Chao-Yang Kuo; Colin Kuo-Chang Wen; Kah-Leng Cherh; Ming-Jay Ho; Nien-Yun Cheng; Yen-Chia Chen; Chaolun Allen Chen (Frontiers in Marine Science, 2021)

Projections from Infralimbic Cortex to Paraventricular Thalamus Mediate Fear Extinction Retrieval - Yan Tao; Cheng-Yun Cai; Jia-Yun Xian; Xiao-Lin Kou; Yu-Hui Lin; Cheng Qin; Hai-Yin Wu; Lei Chang; Chun-Xia Luo; Dong-Ya Zhu (Neuroscience Bulletin, 2021)

NDRG2 is expressed on enteric glia and altered in conditions of inflammation and oxygen glucose deprivation/reoxygenation - Yuxin Zhang; Hui Gao; Na Li; Haiqing Chang; Bo Cheng; Yansong Li; Jiwen Miao; Shuang Li; Qiang Wang (Journal of Molecular Histology, 2021)

Effects of physical driving experience on body movement and motion sickness among passengers in a virtual vehicle - Chih-Hui Chang; Thomas A. Stoffregen; Kuangyou B. Cheng; Man Kit Lei; Chung-Chieh Li (Experimental Brain Research, 2021)

RNA m6A methylation promotes the formation of vasculogenic mimicry in hepatocellular carcinoma via Hippo pathway - Kailiang Qiao; Yantao Liu; Zheng Xu; Haohao Zhang; Heng Zhang; Chao Zhang; Zhi Chang; Xinyan Lu; Zhongwei Li; Ce Luo; Yanrong Liu; Cheng Yang; et al. (Angiogenesis, 2021)

PapA , a peptidoglycan‐associated protein, interacts with OmpC and maintains cell envelope integrity - Yun‐Hao Wang; Hong‐He Chen; Zhou Huang; Xiao‐Jing Li; Nan Zhou; Chang Liu; Cheng‐Ying Jiang; De‐Feng Li; Shuang‐Jiang Liu (Environmental Microbiology, 2021)
Summary The bacterial cell envelope is critical to support and maintain cellular life. In Gram‐negative bacterial cells, the outer membrane and the peptidoglycan layer are two important parts of the cell envelope and they harbour abundant proteins. Here, we report the identification and characterization of a previously unknown p eptidoglycan‐ a ssociated p rotein, PapA, from the Gram‐negative Comamonas testosteroni . PapA bound peptidoglycan with its C‐terminal domain and interacted with the outer‐membrane porin OmpC. The PapA‐OmpC complex riveted the outer membrane and the peptidoglycan layer, and played a role in maintaining cell envelope integrity. When papA was disrupted, the mutant CNB‐1Δ papA apparently had an outer membrane partly separated from the peptidoglycan layer. Phenotypically, the mutant CNB‐1Δ papA lost chemotactic responses and had longer lag‐phase of growth, less flagellation and higher sensitivity to harsh environments. Totally, 1093 functionally unknown PapA homologues were identified from the public NR protein database and they were mainly distributed in Burkholderiales of Betaproteobacteria. Our finding provides a clue that the PapA homologous proteins might function as a rivet to maintain cell envelope integrity in those Gram‐negative bacteria.

The substrate‐dependent regulatory effects of the AfeI /R system in Acidithiobacillus ferrooxidans reveals the novel regulation strategy of quorum sensing in acidophiles - Xue‐Yan Gao; Chang‐Ai Fu; Likai Hao; Xiu‐Feng Gu; Rui Wang; Jian‐Qiang Lin; Xiang‐Mei Liu; Xin Pang; Cheng‐Jia Zhang; Jian‐Qun Lin; Lin‐Xu Chen (Environmental Microbiology, 2021)
Summary A LuxI/R‐like quorum sensing (QS) system (AfeI/R) has been reported in the acidophilic and chemoautotrophic Acidithiobacillus spp. However, the function of AfeI/R remains unclear because of the difficulties in the genetic manipulation of these bacteria. Here, we constructed different afeI mutants of the sulfur‐ and iron‐oxidizer A . ferrooxidans , identified the N‐acyl homoserine lactones (acyl‐HSLs) synthesized by AfeI, and determined the regulatory effects of AfeI/R on genes expression, extracellular polymeric substance synthesis, energy metabolism, cell growth and population density of A . ferrooxidans in different energy substrates. Acyl‐HSLs‐mediated distinct regulation strategies were employed to influence bacterial metabolism and cell growth of A . ferrooxidans cultivated in either sulfur or ferrous iron. Based on these findings, an energy‐substrate‐dependent regulation mode of AfeI/R in A . ferrooxidans was illuminated that AfeI/R could produce different types of acyl‐HSLs and employ specific acyl‐HSLs to regulate specific genes in response to different energy substrates. The discovery of the AfeI/R‐mediated substrate‐dependent regulatory mode expands our knowledge on the function of QS system in the chemoautotrophic sulfur‐ and ferrous iron‐oxidizing bacteria, and provides new insights in understanding energy metabolism modulation, population control, bacteria‐driven bioleaching process, and the coevolution between the acidophiles and their acidic habitats.

Quantifying Coral Reef Resilience to Climate Change and Human Development: An Evaluation of Multiple Empirical Frameworks - Ashley H. Y. Bang; Chao-Yang Kuo; Colin Kuo-Chang Wen; Kah-Leng Cherh; Ming-Jay Ho; Nien-Yun Cheng; Yen-Chia Chen; Chaolun Allen Chen (Frontiers in Marine Science, 2021)
The integrity of coral reefs has increasingly been threatened by human development and climate change. As a result, the concept of ecological resilience – an ecosystem's capability to resist and recover from environmental stressors – has become an important aspect of coral reef conservation. In this study, coral reef resilience was quantitatively scored in Kenting National Park (KNP), Taiwan, using four different assessment frameworks: the first uses the opinions of local reef experts, the second includes metrics specific to the local reef context, the third combines the previous two approaches, and the fourth relies solely on ecological metrics from biodiversity surveys. To evaluate the accuracy of each assessment, the resulting resilience scores were compared with historical coral recovery rates, which served as a proxy for resilience. While each approach to measuring resilience has its merits and drawbacks, the picture of resilience became clearest when a few key indicators were included to reflect core ecosystem processes. Trends in resilience scores varied depending on the makeup of the assessment's indicators, and there was little correlation between the baseline metrics measured using different data collection methods. However, all resilience assessment trends indicated that KNP's Nanwan area is high in resilience. This is likely due to the effects of local tidally-induced upwelling, which significantly relieve the growing thermal stress placed on surrounding coral communities. Ultimately, the most successful assessments were those that empirically quantified ecological processes and local factors with only a few indicators, rather than broader approaches that measured many indicators. These findings are particularly relevant for reef managers to consider as they develop and employ resilience-based management strategies.

A CCR4-associated factor 1, OsCAF1B, confers tolerance of low-temperature stress to rice seedlings - Jhen-Cheng Fang; Yin-Chuan Tsai; Wei-Lun Chou; Hsin-Yi Liu; Chun-Chen Chang; Shaw-Jye Wu; Chung-An Lu (Plant Molecular Biology, 2021)

FOXO3 is targeted by miR-223-3p and promotes osteogenic differentiation of bone marrow mesenchymal stem cells by enhancing autophagy - Cheng Long; Shiqiang Cen; Zhou Zhong; Chang Zhou; Gang Zhong (Human Cell, 2021)
Mesenchymal stem cells (MSCs) are a promising regenerative medicine. The roles of miRNAs in osteogenic differentiation of bone marrow MSCs (BM-MSCs) remained less reported. Forkhead Box O3 (FOXO3) and alkaline phosphatase (ALP) levels in the BM-MSCs were measured on 3, 7, and 14 days after osteogenic differentiation. After transfection of FOXO3 overexpression plasmids or siFOXO3 into BM-MSCs, factors related to osteogenic differentiation or cell autophagy were determined. Besides, 3-methyladenine or rapamycin, as well as miR-223-3p mimic or inhibitor were applied to further determine the effect of FOXO3 in BM-MSCs. FOXO3 and ALP levels were increased in a time-dependent manner with osteogenic differentiation, supported by Alizarin Red Staining. Furthermore, up-regulated FOXO3 increased levels of ALP and factors related to osteogenic differentiation by increasing levels of autophagy-related factors. FOXO3, targeted by miR-223-3p, reversed the effects of miR-223-3p on factors related to BM-MSC autophagy and osteogenic differentiation. Down-regulated miR-223-3p expression promoted osteogenic differentiation of BM-MSCs by enhancing autophagy via targeting FOXO3, suggesting the potential of miR-223-3p as a therapeutic target for enhancing bone functions.

Long-term impact of accidental pollution on the distribution and risks of metals and metalloids in the sediment of the Longjiang River, China - Qian-Li Ma; Ling-Ai Yao; Qing-Wei Guo; Guang-Jie Zhou; Rong-Chang Liang; Qiao-Li Fang; Zhen-Cheng Xu; Xue-Min Zhao (Environmental Science and Pollution Research, 2021)

Land-use changes and ecosystem services under different scenarios in Nansi Lake Basin, China - Yande Jing; Yuqing Chang; Xiyu Cheng; Dan Wang (Environmental Monitoring and Assessment, 2021)

Concurrent increases in post-pacing action potential duration and contractility predict occurrence of ventricular arrhythmia - Chih-Min Liu; Feng-Zhi Lin; Yao-Chang Chen; Yung-Kuo Lin; Yen-Yu Lu; Cheng-I Wu; Satoshi Higa; Shih-Ann Chen; Yi-Jen Chen (Pflügers Archiv - European Journal of Physiology, 2020)

The Effects of Non-invasive Brain Stimulation on Impulsivity in People with Mental Disorders: a Systematic Review and Explanatory Meta-Analysis - Cheng-Chang Yang; Laura Mauer; Birgit Völlm; Najat Khalifa (Neuropsychology Review, 2020)

Treatment of murine colitis by Saccharomyces boulardii secreting atrial natriuretic peptide - Cheng-Hao Liu; Jen-Hsuan Chang; You-Chiun Chang; Kurt Yun Mou (Journal of Molecular Medicine, 2020)

A Clipless Pedal-Sensor System for Three Dimensional Kinetic Analysis During Cycling - Kai-Han Liang; Hong-Wen Wu; Li-Cheng Hsieh; Yi-Wen Chang (Journal of Medical and Biological Engineering, 2020)

Geographical origin differentiation of Chinese Angelica by specific metal element fingerprinting and risk assessment - Lei Sun; Xiao Ma; Hong-Yu Jin; Chang-jun Fan; Xiao-dong Li; Tian-Tian Zuo; Shuang-Cheng Ma; Sicen Wang (Environmental Science and Pollution Research, 2020)

Differential time-lag effects of ambient PM2.5 and PM2.5-bound PAHs on asthma emergency department visits - Shih-Chang Hsu; Jer-Hwa Chang; Chon-Lin Lee; Wen-Cheng Huang; Yuan-Pin Hsu; Chung-Te Liu; Shio-Shin Jean; Shau-Ku Huang; Chin-Wang Hsu (Environmental Science and Pollution Research, 2020)

Comparative performance assessment of landslide susceptibility models with presence-only, presence-absence, and pseudo-absence data - Dong-mei Zhao; Yuan-mei Jiao; Jin-liang Wang; Yin-ping Ding; Zhi-lin Liu; Cheng-jing Liu; Ying-mei Qiu; Juan Zhang; Qiu-e Xu; Chang-run Wu (Journal of Mountain Science, 2020)

Isolation and characterization of 100 SNP markers in lined seahorse (Hippocampus erectus) using RAD sequencing - Ke-Cheng Zhu; Qiwei Ma; Dian-Chang Zhang (Conservation Genetics Resources, 2020)

Sulfide ore prospecting in carbon-containing stratum using comprehensive time-domain induced polarization and controlled-source audio-frequency magnetotellurics - Ren-Bin Sun; Li-Xia Chu; Gui-Bin Zhang; Qiu-Ming Cheng; Yun-Chuan Xiang; Bin Hu; Chang-Rong Zhang; Jian-Fu Li; Yi-Jun Zhao (Applied Geophysics, 2020)

Optimizing the MIC breakpoints of amoxicillin and tetracycline for antibiotic selection in the rescue therapy of H. pylori with bismuth quadruple regimen - Ming-Tsung Hsieh; Wei-Lun Chang; Chung-Tai Wu; Hsiao-Bai Yang; Hsin-Yu Kuo; Meng-Ying Lin; Hsiu-Chi Cheng; Yu-Chin Tsai; Bor-Shyang Sheu (European Journal of Clinical Pharmacology, 2020)

Prevalence of Clonorchis sinensis infection in fish in South‐East Asia: A systematic review and meta‐analysis - Ying Zhang; Qing‐Long Gong; Qing‐Bo Lv; Yang‐Yuan Qiu; Yan‐Chun Wang; Hong‐Yu Qiu; Xin‐Rui Guo; Jun‐Feng Gao; Qiao‐Cheng Chang; Chun‐Ren Wang (Journal of Fish Diseases, 2020)
Clonorchis sinensis , an important fish‐borne zoonotic trematode, is widely distributed in South‐East Asia, especially in China. Infections from human and animal reservoir hosts occur due to the consumption of raw or undercooked fish with C. sinensis metacercariae. This study aimed to evaluate the prevalence of C. sinensis metacercariae in fish in South‐East Asia via systematic review and meta‐analysis. We searched PubMed, ScienceDirect, China National Knowledge Infrastructure, Wanfang and Chongqing VIP databases for studies published between 1976 and 2020 that are related to the prevalence of C. sinensis metacercariae in fish. Studies were screened with keywords based on inclusion and exclusion criteria. Seventy‐one eligible articles were identified, covering three countries: China, Korea and Vietnam. The pooled prevalence of C. sinensis metacercariae in fish from South‐East Asia was 30.5%, with 35.1% in China, 29.7% in Korea and 8.4% in Vietnam. In subgroup analyses of climate, season, water source and publication date, the highest prevalence was identified in the Dwb climate type (43.3%), summer (70.2%), river (34.5%) and pre‐2001 publications (38.9%), respectively. In comparison, the lowest prevalence was found in the Dfa climate type (14.5%), winter (19.5%), lake (8.0%) and post‐2001 publications (23.8%). Meta‐regression results indicated that country ( p = .009), the published time ( p = .035) and water source subgroups ( p = .003) may be the source of heterogeneity. Overall, our study indicates that a high prevalence of C. sinensis infections occurs in fish in China, Korea and Vietnam, illuminating a significant public health concern in these countries.

Matriptase and prostasin proteolytic activities are differentially regulated in normal and wounded skin - Shun-Cheng Chang; Chien-Ping Chiang; Chih-Hsin Lai; Po-Wen A. Du; Yu-Sin Hung; Yu-Hsuan Chen; Hui-Yu Yang; Hao-Yu Fang; Shiao-Pieng Lee; Hung-Jen Tang; Jehng-Kang Wang; Michael D. Johnson; et al. (Human Cell, 2020)

Removal of polycyclic aromatic hydrocarbon (PAH)-contaminated sediments by persulfate oxidation and determination of degradation product cytotoxicity based on HepG2 and ZF4 cell lines - Cheng-Di Dong; Mei-Ling Tsai; Tsing-Hai Wang; Jih-Hsing Chang; Chiu-Wen Chen; Chang-Mao Hung (Environmental Science and Pollution Research, 2020)

Upregulation of miR-133a-3p in the Sciatic Nerve Contributes to Neuropathic Pain Development - Lin-Li Chang; Hung-Chen Wang; Kuang-Yi Tseng; Miao-Pei Su; Jaw-Yuan Wang; Yi-Ta Chuang; Yi-Hsuan Wang; Kuang-I Cheng (Molecular Neurobiology, 2020)

Genesis of the Linghu Au deposit in Xiaoqinling Region, Henan province, China: Constraints from fluid inclusions and isotope systematics - Wei Zeng; Zhi-gao Wang; Duo Wan; Feng-yue Sun; Cheng-dong Li; Reng-an Yu; Jia-ying Wang; Jian-chang Xu (Arabian Journal of Geosciences, 2020)

Two new diprenylated flavanones from Derris laxiflora Benth - Hui-Chi Huang; Shih-Chang Chien; Ching-Chuan Kuo; Ming-Der Wu; Ming-Jen Cheng; Jih-Jung Chen; Hsi-Lin Chiu; Yueh-Hsiung Kuo (Natural Product Research, 2020)

Blockade of HCN2 Channels Provides Neuroprotection Against Ischemic Injury via Accelerating Autophagic Degradation in Hippocampal Neurons - Cheng Chen; Li Liu; Ya-Qiao Shu; Ping Jing; Yun Lu; Xiao-Xue Zhang; Xian-Gang Zong; Lian-Jun Guo; Chang-Jun Li (Neuroscience Bulletin, 2020)

A Near Infrared Spectroscopy System for Assessing Rehabilitation on Peripheral Arterial Occlusion Patients - Shao-Hung Lu; Cheng-Lun Tsai; Tieh-Cheng Fu; Po-Hung Chang; Shao-Ming Lu (Journal of Medical and Biological Engineering, 2020)
Purpose A near-infrared spectroscopy system was developed to evaluate peripheral arterial occlusive disease (PAOD). The wireless device can take measurements when patients are doing rehabilitation exercise. Methods Two LED modules with wavelengths of 740 nm, 808 nm and 850 nm were placed over 32 mm away from the photodiode to detect the deep backscattering from muscle tissue. The absorbance difference from the extent of tissue oxygenation was extracted using a modified Beer’s law. Measurements taken on different muscle groups were applied to determine which branch of artery is occluded. Results The changes in oxygenation of gastrocnemius and tibialis anterior muscle were recorded when PAOD patients were riding a stationary bicycle. The drop in oxygenation with exercise generally should recover within 15 min of continuing exercise. Otherwise, the artery is not capable to provide enough blood supply to the exercising muscles. Since gastrocnemius is the primary muscle used in biking exercise, the compensatory vasodilation in gastrocnemius leads to hypoperfusion in tibialis anterior muscle. Conclusion This NIRS system is helpful for detecting the changes in tissue oxygenation during exercise. Muscle hypoxia was more obvious during exercise when the artery had some degree of occlusion.

The Health Promoting Mindfulness or Qigong Educational Programs for Beneficial Lifestyle Changes of Cancer Survivors - Tse-Chou Cheng; Yi-Hua Lee; Chun-Lin Mar; Wen-Tsung Huang; Yuan-Ping Chang (Journal of Cancer Education, 2020)

Mixture of Pb, Zn and Cu on root permeability and radial oxygen loss in the mangrove Bruguiera gymnorrhiza - Hao Cheng; You-Shao Wang; Chang-Da Li; Zhi-Hong Ye; Shafi Muhammad; Mei-Lin Wu; Fun-Lin Sun (Ecotoxicology, 2020)

Dynamics of radial oxygen loss in mangroves subjected to waterlogging - Hao Cheng; Mei-Lin Wu; Chang-Da Li; Fu-Lin Sun; Cui-Ci Sun; You-Shao Wang (Ecotoxicology, 2020)

Salt tolerance and exclusion in the mangrove plant Avicennia marina in relation to root apoplastic barriers - Hao Cheng; Anifiok Inyang; Chang-Da Li; Jiao Fei; Yan-Wu Zhou; You-Shao Wang (Ecotoxicology, 2020)

Reconnaissance and learning after the February 6, 2018, earthquake in Hualien, Taiwan - Jui-Liang Lin; Chun-Hsiang Kuo; Yu-Wen Chang; Shu-Hsien Chao; Yi-An Li; Wen-Cheng Shen; Chung-Han Yu; Cho-Yen Yang; Fan-Ru Lin; Hsiao-Hui Hung; Chun-Chung Chen; Chin-Kuo Su; et al. (Bulletin of Earthquake Engineering, 2020)

Relationship Between Seismic Moment and Source Duration for Seismogenic Earthquakes in Taiwan: Implications for the Product of Static Stress Drop and the Cube of Rupture Velocity - Ruey-Der Hwang; Cheng-Ying Ho; Tzu-Wei Lin; Wen-Yen Chang; Yi-Ling Huang; Cai-Yi Lin; Chiung-Yao Lin (Pure and Applied Geophysics, 2020)

The trichome-specific acetolactate synthase NtALS1 gene, is involved in acylsugar biosynthesis in tobacco (Nicotiana tabacum L.) - Ai-Xia Chang; Biao Chen; Ai-Guo Yang; Ri-Sheng Hu; Quan-Fu Feng; Ming Chen; Xiao-Ning Yang; Cheng-Gang Luo; Yang-Yang Li; Yuan-Ying Wang (Planta, 2020)