Two-dimensional hydrodynamic modeling for prediction of bank erosion and bed incision in the Indus River - Muhammad Waseem Boota; Chaode Yan; Shan-e-hyder Soomro; Muhammad Awais Zafar; Ziwei Li; Jikun Xu; Ayesha Yousaf (Acta Geophysica, 2023)

Western diet unmasks transient low-level vinyl chloride-induced tumorigenesis; potential role of the (epi-)transcriptome - Silvia Liu; Liqing He; Olivia B. Bannister; Jiang Li; Regina D. Schnegelberger; Charis-Marie Vanderpuye; Andrew D. Althouse; Francisco J. Schopfer; Banrida Wahlang; Matthew C. Cave; Satdarshan P. Monga; Xiang Zhang; et al. (Toxicology and Applied Pharmacology, 2023)

Inter-regional environmental inequality under lasting pandemic exacerbated by residential response - Chunjin Li; Jintai Lin; Lulu Chen; Qi Cui; Yu Liu; Erin E. McDuffie; Mingxi Du; Hao Kong; Jingxu Wang (Science of The Total Environment, 2023)

Streamline unsupervised machine learning to survey and graph indel-based haplotypes from pan-genomes - Bosen Zhang; Haiyan Huang; Laura E. Tibbs-Cortes; Adam Vanous; Zhiwu Zhang; Karen Sanguinet; Kimberly A. Garland-Campbell; Jianming Yu; Xianran Li (Molecular Plant, 2023)

Late Cenozoic history and the role of Beringia in assembling a Holarctic cestode species complex - Kurt E. Galbreath; Arseny A. Makarikov; Kayce C. Bell; Stephen E. Greiman; Julie M. Allen; Genevieve M.S. Haas; Chenhong Li; Joseph A. Cook; Eric P. Hoberg (Molecular Phylogenetics and Evolution, 2023)

Investigation of free amino acids in lactic acid bacteria fermented milk and their ability to activate the calcium sensing receptor - Raise Ahmad; Julie E. Dalziel; Hanh T.H. Nguyen; John Rounce; Li Day; Evelyne Maes (International Dairy Journal, 2023)

A rapid chemometrics model for antioxidant substance mining of Chinese dwarf cherry [Cerasus humilis (Bge.) Sok.] based on polyphenol profile and antioxidant capacity of 30 germplasms - Yushi Zhang; Qingyu Cui; Chang-e Guo; Xiaobing Zhang; Shupeng Liu; Xiaoxue Wang; Jinjiang Zhao; Zihan Zhao; Weidong Li (Food Bioscience, 2023)

Long-term application of controlled-release potassium chloride increases maize yield by affecting soil bacterial ecology, enzymatic activity and nutrient supply - Zeli Li; Lixue Qiu; Tianjiao Zhang; Gaoyang E; Lili Zhang; Lingli Wang; Liang Wu; Yanfeng Wang; Yunfeng Zhang; Jun Dong; Wenjing Li; Zhiguang Liu; et al. (Field Crops Research, 2023)

Fatigue strengthening of damaged steel members using wire arc additive manufacturing - E. Ghafoori; H. Dahaghin; C. Diao; N. Pichler; L. Li; M. Mohri; J. Ding; S. Ganguly; S. Williams (Engineering Structures, 2023)

Impact of different nitrogen additions on microbes and exopolysaccharides excretion in cyanobacterial biocrusts - Long Qian; Jingshang Xiao; Zulin Zhang; Lie Yang; Ling Xia; María E. Farías; Rosa María Torres; Li Wu (Plant and Soil, 2023)

Three-dimensional microCT imaging of mouse heart development from early post-implantation to late fetal stages - Nanbing Li-Villarreal; Tara L. Rasmussen; Audrey E. Christiansen; Mary E. Dickinson; Chih-Wei Hsu (Mammalian Genome, 2023)
Comprehensive detailed characterization of new mouse models can be challenging due to the individual focus involved in developing these models. Often models are engineered to test a specific hypothesis in a limited number of tissues, stages, and/or other contexts. Whether or not the model produces the desired phenotypes, phenotyping beyond the desired context can be extremely work intensive and these studies are often not undertaken. However, the general information resulting from broader phenotyping can be invaluable to the wider scientific community. The International Mouse Phenotyping Consortium (IMPC) and its subsidiaries, like the Knockout Mouse Project (KOMP), has made great strides in streamlining this process. In particular, the use of microCT has been an invaluable resource in examining internal organ systems throughout fetal/developmental stages. Here, we provide several novel vignettes demonstrating the utility of microCT in uncovering cardiac phenotypes both based on human disease correlations and those that are unpredicted.

Correction to: Protecting pollinators and our food supply: understanding and managing threats to pollinator health - H. Siviter; A. Fisher; B. Baer; M. J. F. Brown; I. F. Camargo; J. Cole; Y. Le Conte; B. Dorin; J. D. Evans; W. Farina; J. Fine; L. R. Fischer; et al. (Insectes Sociaux, 2023)

Correction to: Spatial patterns of extreme precipitation and their changes under ~ 2 °C global warming: a large-ensemble study of the western USA - David E. Rupp; Linnia R. Hawkins; Sihan Li; Matthew Koszuta; Nicholas Siler (Climate Dynamics, 2023)

Establishment of Agrobacterium-mediated transformation system to Juglans sigillata Dode ‘Qianhe-7’ - Rong Wei; Wen’e Zhang; Chunxiang Li; Zhenkun Hao; Dong Huang; Wenlong Zhang; Xuejun Pan (Transgenic Research, 2023)

Another Year of Record Heat for the Oceans - Lijing Cheng; John Abraham; Kevin E. Trenberth; John Fasullo; Tim Boyer; Michael E. Mann; Jiang Zhu; Fan Wang; Ricardo Locarnini; Yuanlong Li; Bin Zhang; Fujiang Yu; et al. (Advances in Atmospheric Sciences, 2023)
Changes in ocean heat content (OHC), salinity, and stratification provide critical indicators for changes in Earth’s energy and water cycles. These cycles have been profoundly altered due to the emission of greenhouse gasses and other anthropogenic substances by human activities, driving pervasive changes in Earth’s climate system. In 2022, the world’s oceans, as given by OHC, were again the hottest in the historical record and exceeded the previous 2021 record maximum. According to IAP/CAS data, the 0–2000 m OHC in 2022 exceeded that of 2021 by 10.9 ± 8.3 ZJ (1 Zetta Joules = 10 21 Joules); and according to NCEI/NOAA data, by 9.1 ± 8.7 ZJ. Among seven regions, four basins (the North Pacific, North Atlantic, the Mediterranean Sea, and southern oceans) recorded their highest OHC since the 1950s. The salinity-contrast index, a quantification of the “salty gets saltier—fresh gets fresher” pattern, also reached its highest level on record in 2022, implying continued amplification of the global hydrological cycle. Regional OHC and salinity changes in 2022 were dominated by a strong La Niña event. Global upper-ocean stratification continued its increasing trend and was among the top seven in 2022.

Decision‐making under uncertainty for species introductions into ecological networks - Lucy B. Van Kleunen; Katie A. Peterson; Meghan T. Hayden; Aislyn Keyes; Aaron J. Schwartz; Henry Li; Laura E. Dee (Ecology Letters, 2023)
Ecological communities are increasingly subject to natural and human‐induced additions of species, as species shift their ranges under climate change, are introduced for conservation and are unintentionally moved by humans. As such, decisions about how to manage ecosystems subject to species introductions and considering multiple management objectives need to be made. However, the impacts of gaining new species on ecological communities are difficult to predict due to uncertainty in introduced species characteristics, the novel interactions that will be produced by that species, and the recipient ecosystem structure. Drawing on ecological and conservation decision theory, we synthesise literature into a conceptual framework for species introduction decision‐making based on ecological networks in high‐uncertainty contexts. We demonstrate the application of this framework to a theoretical decision surrounding assisted migration considering both biodiversity and ecosystem service objectives. We show that this framework can be used to evaluate trade‐offs between outcomes, predict worst‐case scenarios, suggest when one should collect additional data, and allow for improving knowledge of the system over time.

Low circulating adropin concentrations predict increased risk of cognitive decline in community-dwelling older adults - Geetika Aggarwal; John E. Morley; Bruno Vellas; Andrew D. Nguyen; Andrew A. Butler; Sophie Guyonnet; Isabelle Carrié; Lauréane Brigitte; Catherine Faisant; Françoise Lala; Julien Delrieu; Hélène Villars; et al. (GeroScience, 2023)
The secreted peptide adropin is highly expressed in human brain tissues and correlates with RNA and proteomic risk indicators for dementia. Here we report that plasma adropin concentrations predict risk for cognitive decline in the Multidomain Alzheimer Preventive Trial (ClinicalTrials.gov Identifier, NCT00672685; mean age 75.8y, SD = 4.5 years, 60.2% female, n = 452). Cognitive ability was evaluated using a composite cognitive score (CCS) that assessed four domains: memory, language, executive function, and orientation. Relationships between plasma adropin concentrations and changes in CCS (∆CCS) were examined using Cox Proportional Hazards Regression, or by grouping into tertiles ranked low to high by adropin values and controlling for age, time between baseline and final visits, baseline CCS, and other risk factors (e.g., education, medication, APOE4 status). Risk of cognitive decline (defined as a ∆CCS of − 0.3 or more) decreased with increasing plasma adropin concentrations (hazard ratio = 0.873, 95% CI 0.780–0.977, P = 0.018). Between adropin tertiles, ∆CCS was significantly different ( P = 0.01; estimated marginal mean ± SE for the 1st to 3rd tertile, − 0.317 ± 0.064; − 0.275 ± 0.063; − 0.042 ± 0.071; n = 133,146, and 130, respectively; P < 0.05 for 1st vs. 2nd and 3rd adropin tertiles). Normalized plasma Aß 42/40 ratio and plasma neurofilament light chain, indicators of neurodegeneration, were significantly different between adropin tertile. These differences were consistent with reduced risk of cognitive decline with higher plasma adropin levels. Overall, these results suggest cognitive decline is reduced in community-dwelling older adults with higher circulating adropin levels. Further studies are needed to determine the underlying causes of the relationship and whether increasing adropin levels can delay cognitive decline.

Shift of phytoplankton and microbial communities cause seasonal dynamics of odor compounds in Oncorhynchus mykiss cultured in a freshwater reservoir - Shuting Li; Fayi Wei; Xuan Dong; Miaojun Pan; Li Li; Xiangli Tian; Qinfeng Gao; Alan E. Wilson (Aquaculture, 2023)

Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition - Jie Yang; Gang Li; Yue'e Huang; Ying Liu (Toxicology and Applied Pharmacology, 2023)

Zircon constraints on gold enrichment in a high-silica porphyry, Yixingzhai region, north of the Trans-North China Orogen - Zi-Hao Wen; Lin Li; Daniel E. Harlov; Sheng-Rong Li (Lithos, 2023)

Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model - Ashley S. Nemec-Bakk; Vijayalakshmi Sridharan; John W. Seawright; Gregory A. Nelson; Maohua Cao; Preeti Singh; Amrita K. Cheema; Bhaldev Singh; Yaoxiang Li; Igor Koturbash; Isabelle R. Miousse; Laura E. Ewing; et al. (Life Sciences in Space Research, 2023)

Proposal of a reliable scoring system for the histological assessment of multiorgan injury in large animal models of ischaemia and shock - C. Palmieri; L. See Hoe; W. Dyer; S. Heinsar; S. Rozencwaig; J.P. Tung; N. Bartnikowski; M. Passmore; M. Bouquet; K. Hislop; E. Wilson; g. Li Bassi; et al. (Journal of Comparative Pathology, 2023)

Machine learning and deep learning based on the small FT-MIR dataset for fine-grained sampling site recognition of boletus tomentipes - Jian-E Dong; Jieqing Li; Honggao Liu; Yuan-Zhong Wang (Food Research International, 2023)

Pore size adjustment of sodium alginate-based composite aerogel spheres by zirconia for efficient selective removal of Cu(II) - Suya Li; Shuyi Yang; Liang Chen; Xin Hao; Tao E; Yun Li (Chemical Engineering Journal, 2023)

Tumor-derived microparticles-based nanomaterial as platform for delivery of tumor antigens to enhance immunogenicity - Qi Tan; Zimo Yang; Shichen Bu; Jiangbin Chen; Wenjuan Chen; Wei Geng; Qi Huang; Limin Duan; Mengfei Guo; Yali Wu; Jingjing Deng; E Zhou; et al. (Chemical Engineering Journal, 2023)

Re-evaluation of equilibrium relationships involving U6+/U4+ and Fe3+/Fe2+ in hydrothermal fluids and their implications for U mineralization - Teng Deng; Guoxiang Chi; Anthony E. Williams-Jones; Zenghua Li; Yumeng Wang; Deru Xu; Zhilin Wang (Chemical Geology, 2023)

Metabolites dynamics exacerbated by external nutrients inputs into a Ceratium hirundinella-dominated bloom in the Pengxi River, Three Gorges Reservoir, China - Amechi S. Nwankwegu; Lei Zhang; Deti Xie; Okugbe E. Ohore; Yiping Li; Guanglang Yang; Xuexing Yao; Zenghui Song; Qing Yang (Aquatic Toxicology, 2023)

Establishment of a point of departure for CBD hepatotoxicity employing human HepaRG spheroids - Jinpeng Li; Joseph W. Zagorski; Norbert E. Kaminski (Toxicology, 2023)

Photolysis frequency of nitrophenols derived from ambient measurements - Yuwen Peng; Bin Yuan; Suxia Yang; Sihang Wang; Xiaoyun Yang; Wenjie Wang; Jin Li; Xin Song; Caihong Wu; Jipeng Qi; E. Zheng; Chenshuo Ye; et al. (Science of The Total Environment, 2023)

Harnessing data assimilation and spatial autocorrelation for forest inventory - Qing Xu; Bo Li; Ronald E. McRoberts; Zengyuan Li; Zhengyang Hou (Remote Sensing of Environment, 2023)

The Bolometric Bond Albedo of Enceladus - Liming Li; Larry Guan; Sherry Li; Cindy Luu; Kevin Heng; Patrick M. Fry; Ellen C. Creecy; Xinyue Wang; Ronald J. Albright; Thishan D. Karandana G.; Xun Jiang; Robert A. West; et al. (Icarus, 2023)

Insights into the pigment and non-pigment phenolic profile of polyphenol extracts of jujube peel and their antioxidant and lipid-lowering activities - Jin-Feng Dou; Cai-E Wu; Gong-Jian Fan; Ting-Ting Li; Xiao-Jing Li; Dan-Dan Zhou; Jin-Peng Zhu; Chun-Mei Li (Food Bioscience, 2023)

Structural annotation and discovery of toxic cyclopeptides and their analogues in lethal mushroom Amanita and Lepiota species using UPLC-HRMS and molecular networking strategy - Zhiyong Zhao; Hengchao E; Enjing Tian; Tingting Fan; Xianli Yang; Xiaobei Li; Yanmei Zhang; Xujiao Li; Ailiang Chen; Changyan Zhou; Xiaoyan Zhao (Food Control, 2023)

Lacustrine-evaporitic microbial dolomite from a Plio-Pleistocene succession recovered by the SG-1 borehole in the Qaidam Basin, NE Tibetan Plateau - Yanyang Zhao; Xiangyu Wei; Zuozhen Han; Chao Han; Xiao Gao; Ruirui Meng; Qiyu Wang; Maurice E. Tucker; Minghui Li; Mónica Sánchez-Román (Chemical Geology, 2023)

Challenges with Cell-based Therapies for Type 1 Diabetes Mellitus - Prakriti Siwakoti; Claire Rennie; Yanan Huang; Jiao Jiao Li; Bernard E Tuch; Lana McClements; Xiaoxue Xu (Stem Cell Reviews and Reports, 2023)

Recapitulation of anti-aging phenotypes by global, but not by muscle-specific, deletion of PAPP-A in mice - Xinna Li; Mary Hager; Madaline McPherson; Michael Lee; Riha Hagalwadi; Mary E. Skinner; David Lombard; Richard A. Miller (GeroScience, 2023)

Kuroshio Intrusion Combined with Coastal Currents Affects Phytoplankton in the Northern South China Sea Revealed by Lipid Biomarkers - Yaoyao Wang; Rong Bi; Jiawei Gao; Hailong Zhang; Li Li; Yang Ding; Gui’e Jin; Meixun Zhao (Journal of Ocean University of China, 2023)

Recent advances in the fabrication of pH-sensitive indicators films and their application for food quality evaluation - Qingying Luo; Alomgir Hossen; Dur E Sameen; Saeed Ahmed; Jianwu Dai; Suqing Li; Wen Qin; Yaowen Liu (Critical Reviews in Food Science and Nutrition, 2023)

Analysing the impact of geopolitical risk and economic policy uncertainty on the environmental sustainability: evidence from BRICS countries - Hua Li; Muhammad Sibt e Ali; Bakhtawer Ayub; Irfan Ullah (Environmental Science and Pollution Research, 2023)

Scavenger receptor BI attenuates oxidized phospholipid-induced pulmonary inflammation - Katelyn Dunigan-Russell; Michael J. Yaeger; Myles X. Hodge; Brita Kilburg-Basnyat; Sky W. Reece; Anastasiya Birukova; Marissa A. Guttenberg; Caymen Novak; Sangwoon Chung; Brandie Michelle Ehrmann; E. Diane Wallace; Debra Tokarz; et al. (Toxicology and Applied Pharmacology, 2023)

Search for CP violation and measurement of branching fractions and decay asymmetry parameters for Λ c + → Λ h + and Λ c + → Σ 0 h + ( h = K , π ) - L.K. Li; W. Shan; K. Kinoshita; I. Adachi; H. Aihara; D.M. Asner; H. Atmacan; T. Aushev; V. Babu; S. Bahinipati; Sw. Banerjee; P. Behera; et al. (Science Bulletin, 2023)

Fish damage due to tubular turbine: Experiments and CFD simulations - Chunxia Yang; Qian Li; Ding'e Xu; Jiawei Wu; Yuan Zheng; Yuquan Zhang; An Yu (Ocean Engineering, 2023)

Number of COVID-19 cases required in a population to detect SARS-CoV-2 RNA in wastewater in the province of Alberta, Canada: Sensitivity assessment - Qiaozhi Li; Bonita E. Lee; Tiejun Gao; Yuanyuan Qiu; Erik Ellehoj; Jiaao Yu; Mathew Diggle; Graham Tipples; Rasha Maal-Bared; Deena Hinshaw; Christopher Sikora; Nicholas J. Ashbolt; et al. (Journal of Environmental Sciences, 2023)

Study of the internal mechanism of L-glutamate for improving the survival rate of Lactiplantibacillus plantarum LIP-1 after freeze-drying - E. Jingjing; Zhang Jingya; Ma Rongze; Chen Zichao; Yao Caiqing; Wang Ruixue; Zhang Qiaoling; Yang Ying; Li Jing; Wang Junguo (Innovative Food Science & Emerging Technologies, 2023)

A comprehensive review on combustion stabilization technologies of micro/meso-scale combustors for micro thermophotovoltaic systems: Thermal, emission, and energy conversion - Lei Cai; Jiaqiang E; Jintao Li; Jiangjun Ding; Bo Luo (Fuel, 2023)

Simple and efficient solid phase extraction based on molecularly imprinted resorcinol–formaldehyde resin nanofibers for determination of trace sulfonamides in animal-origin foods - Yuanyuan Dai; Niu Wu; Li-e Liu; Fei Yu; Yongjun Wu; Ningge Jian (Food Chemistry, 2023)

Effects of palm olein and palm stearin on cecal and fecal microbiota of C57BL/6J mice under low and high fat intakes - Liting Wan; Lin Li; Xia Zhang; Bing Li; Janette M. Harro; Mark E. Shirtliff (Food Chemistry, 2023)

Networks of placental DNA methylation correlate with maternal serum PCB concentrations and child neurodevelopment - Julia S. Mouat; Xueshu Li; Kari Neier; Yihui Zhu; Charles E. Mordaunt; Michele A. La Merrill; Hans-Joachim Lehmler; Michael P. Jones; Pamela J. Lein; Rebecca J. Schmidt; Janine M. LaSalle (Environmental Research, 2023)

Trends in elemental Pb concentrations within atmospheric PM2.5 and associated risk to human health in major cities of China - Qian Cui; Liangzhong Li; Yaqiang Cao; Bo Yang; Lindou Liu; Xiaoyan Dong; Yu'e Cha; Hongjie Ruan; Song Tang; Qiong Wang (Environmental Pollution, 2023)

Bacterial anomalies associated with deep sea hydrocarbon seepage along the Scotian Slope - Carmen Li; Oyeboade Adebayo; Deidra K. Ferguson; Scott Wang; Jayne E. Rattray; Martin Fowler; Jamie Webb; Calvin Campbell; Natasha Morrison; Adam MacDonald; Casey R.J. Hubert (Deep Sea Research Part I: Oceanographic Research Papers, 2023)

A 1000-year hydroclimate record from the Asian summer monsoon-Westerlies transition zone in the northeastern Qinghai-Tibetan Plateau - Luo Qin; Guangxin Liu; Xiangzhong Li; E. Chongyi; Jiang Li; Changrun Wu; Xin Guan; Yuan Wang (Climatic Change, 2023)

A Device for Transcutaneous Stimulation of the Diaphragm - R. V. Li; N. N. Potrakhov; A. A. Ukhov; S. V. Shapovalov; L. E. Klyachkin; N. T. Bagraev; A. M. Malyarenko; V. A. Mazurok (Biomedical Engineering, 2023)

Cloning and expression of tonoplast membrane intrinsic protein genes in leaves of Vitis heyneana and overexpression of VhTIP2;1 in Arabidopsis confer drought tolerance - Wen’e Zhang; Jingming Hu; Fei Li; Erjuan Chen; Ting Zhao; Xuejun Pan (Acta Physiologiae Plantarum, 2023)

Spatio‐temporal patterns in the woodiness of flowering plants - Ao Luo; Xiaoting Xu; Yunpeng Liu; Yaoqi Li; Xiangyan Su; Yichao Li; Tong Lyu; Dimitar Dimitrov; Markku Larjavaara; Shijia Peng; Yongsheng Chen; Qinggang Wang; et al. (Global Ecology and Biogeography, 2023)
Aim Woody and herbaceous habits represent one of the most distinct contrasts among angiosperms, and the proportion of woody species in floras (i.e., “woodiness” hereafter) represents a fundamental structural element of plant diversity. Despite its core influence on ecosystem processes, spatio‐temporal patterns in woodiness remain poorly understood. Here, we aim to demonstrate the global spatio‐temporal patterns in angiosperm woodiness and their relationship with environmental factors. Location Global. Time period Cenozoic, 66 Ma to present. Major taxa studied Angiosperms. Methods Using newly compiled data on the growth forms and distributions of c . 300,000 angiosperm species and an angiosperm phylogeny, we mapped the current global geographical patterns in angiosperm woodiness, reconstructed ancestral states of growth forms through the angiosperm phylogeny and demonstrated the Cenozoic evolutionary dynamics of woodiness. We evaluated the relationships between woodiness and current climate and palaeoclimate. Results We found that c . 42.7% of angiosperms are woody. Woodiness decreased spatially from the equator towards high latitudes, temporally since the early Cenozoic. Temperature was the best predictor of the spatio‐temporal decline in woodiness and was positively correlated with woodiness. Despite the temporal decline in woodiness, macroevolutionary herbaceous‐to‐woody transitions increased through time and contributed to the evolution of woody floras in temperate drylands, whereas the opposite transitions decreased through time and contributed to herbaceous floras in tropical and subtropical drylands. Main conclusions Our study improves understanding of the spatio‐temporal dynamics of angiosperm woodiness. Our findings suggest that temperature is likely to be a determinant of spatio‐temporal variations in woodiness, highlighting the role of temperature in maintaining the growth form composition of ecosystems. Our study also calls for attention to growth form transitions (e.g., secondary woodiness) in temperate drylands that have been neglected before.

A novel hybrid random forest linear model approach for forecasting groundwater fluoride contamination - Mouigni Baraka Nafouanti; Junxia Li; Edwin E. Nyakilla; Grant Charles Mwakipunda; Alvin Mulashani (Environmental Science and Pollution Research, 2023)

Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter - Baoqiang Li; Andriy Yabluchanskiy; Stefano Tarantini; Srinivasa Rao Allu; Ikbal Şencan-Eğilmez; Ji Leng; Mohammed Ali H. Alfadhel; Jason E. Porter; Buyin Fu; Chongzhao Ran; Sefik Evren Erdener; David A. Boas; et al. (GeroScience, 2023)

How Comamonas testosteroni and Rhodococcus ruber enhance nitrification in the presence of quinoline - Ge Zhu; Haiyun Zhang; Ru Yuan; Meng Huang; Fei Liu; Mo Li; Yongming Zhang; Bruce E. Rittmann (Water Research, 2023)

Multi-stage planning of LID-GREI urban drainage systems in response to land-use changes - Yu Zhang; Mo Wang; Dongqing Zhang; Zhongming Lu; Amin E. Bakhshipour; Ming Liu; Zhiyu Jiang; Jianjun Li; Soon Keat Tan (Science of The Total Environment, 2023)

Effects of exogenous organic/inorganic nitrogen addition on carbon pool distribution and transformation in grassland soil - Menghan Wang; Fucui Li; Lili Dong; Xiang Wang; Liebao Han; Jørgen E. Olesen (Science of The Total Environment, 2023)

Histological types of lung cancer attributable to fine particulate, smoking, and genetic susceptibility - Xiaojie Wang; Tingting Wang; Junjie Hua; Miao Cai; Zhengmin Qian; Chongjian Wang; Haitao Li; Stephen Edward McMillin; Hannah E. Aaron; Chuanbo Xie; Hualiang Lin (Science of The Total Environment, 2023)

Enhanced degradation of bisphenol A: Influence of optimization of removal, kinetic model studies, application of machine learning and microalgae-bacteria consortia - Wenxian Fu; Xiong'e Li; Yuru Yang; Donghui Song (Science of The Total Environment, 2023)

Airborne hyperspectral imaging of cover crops through radiative transfer process-guided machine learning - Sheng Wang; Kaiyu Guan; Chenhui Zhang; Chongya Jiang; Qu Zhou; Kaiyuan Li; Ziqi Qin; Elizabeth A. Ainsworth; Jingrui He; Jun Wu; Dan Schaefer; Lowell E. Gentry; et al. (Remote Sensing of Environment, 2023)

Prehistoric sea-salt manufacture as an adaptation strategy to coastal flooding in East China - Tongtong Zheng; Shao Lei; Zhanghua Wang (王张华); Wenjing Li; Shuwen Mei; Jiehua Wang; Michael E. Meadows (Quaternary Science Reviews, 2023)

Biological conversion of sulfisoxazole in an autotrophic hydrogen-based membrane biofilm reactor - Lin Yang; Si Pang; Jingzhou Zhou; Chengyang Wu; Xiaodi Li; Mengying Yao; Siqing Xia; Bruce E. Rittmann (Journal of Water Process Engineering, 2023)

Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens - Quan Mo; Muhammad Fakhar-e-Alam Kulyar; Chuxian Quan; Yanmei Ding; Yan Zhang; Lihong Zhang; Huachun Pan; Jiakui Li (Journal of Hazardous Materials, 2023)

Characterization of a new chlorimuron-ethyl-degrading strain Cedecea sp. LAM2020 and biodegradation pathway revealed by multiomics analysis - Qingyun Ma; Xiaoyan Han; Jinlong Song; Jie Wang; Qingqing Li; Rebecca E. Parales; Lin Li; Zhiyong Ruan (Journal of Hazardous Materials, 2023)

Opportunities to reduce energy consumption and CO₂ emissions from ironmaking blast furnace using CO₂ electrolysis to CO for carbon recycling - Yichao Hu; Thomas E. Rufford; Jian Chen; Liangyuan Hao; Mengran Li; Yinxuan Qiu; Sahil Garg; Victor Rudolph; Geoff Wang (Journal of Cleaner Production, 2023)

Ecophysiology of seed dormancy and germination in the alpine-subalpine medicinal plant species Sinopodophyllum hexandrum (Royle) T. S. Ying - De-Li Peng; Bo-Yang Geng; Ying-Bo Qin; Li-E Yang; Carol C. Baskin; Jerry M. Baskin (Journal of Applied Research on Medicinal and Aromatic Plants, 2023)

Rice straw application improves yield marginally and increases carbon footprint of double cropping paddy rice (Oryza sativa L.) - Xiaobo Qin; Yanhong Lu; Yunfan Wan; Bin Wang; Jun Nie; Yu’e Li; Yulin Liao (Field Crops Research, 2023)

A 15-year follow-up study of mortality in a pooled cohort of World Trade Center rescue and recovery workers - Jiehui Li; Charles B. Hall; Janette Yung; Rebecca D. Kehm; Rachel Zeig-Owens; Ankura Singh; James E. Cone; Robert M. Brackbill; Mark R. Farfel; Baozhen Qiao; Maria J. Schymura; Moshe Z. Shapiro; et al. (Environmental Research, 2023)

Combining molecular simulation and experiment to understand the effect of moisture on methane adsorption in kerogens - Wei Li; Lee A. Stevens; Bo Zhang; Dingye Zheng; Colin E. Snape (Chemical Engineering Journal, 2023)

Sequential melting of deep crustal source rocks in a rift system: An example from southern Tibet - Li-E Gao; Lingsen Zeng; Linghao Zhao; Lilong Yan (Chemical Geology, 2023)

Calcification of cell membranes: From ions to minerals - Xiao Gao; Jie Li; Kaiming Hu; Yanyang Zhao; Yu Han; Fang Liu; Maurice E. Tucker; Zuozhen Han (Chemical Geology, 2023)

Oxidative stress induced by plasma-activated water stimulates astaxanthin production in Phaffia rhodozyma - Wenshao Li; Carlos H. Luna-Flores; Raveendra Anangi; Renwu Zhou; Xinle Tan; Marius Jessen; Lian Liu; Rusen Zhou; Tianqi Zhang; Alexander Gissibl; Patrick J. Cullen; Kostya (Ken) Ostrikov; et al. (Bioresource Technology, 2023)

Short-term ambient particulate matter pollution of different sizes and respiratory hospital admission in the Beibu Gulf area of Southern China - Haopeng Li; Lizhong Liang; Shiyu Zhang; Zhengmin (Min) Qian; Miao Cai; Xiaojie Wang; Stephen Edward McMillin; Amy E. Keith; Jing Wei; Yan Geng; Hualiang Lin (Atmospheric Environment, 2023)

An Efficient Protocol for Agrobacterium-Mediated Transformation and Regeneration of Sugar Beet (Beta vulgaris L.) based on Blade–Petiole Transition Zone Explants - Ziqiang Zhang; Huizhong Zhang; Liang Wang; Bizhou Zhang; Zengjuan Fu; Shangmin Zhao; E Yuanyuan; Wenzhe Zheng; Hui Zhang; Pingan Han; Wenjin Chen; Yue Chang; et al. (Sugar Tech, 2023)

Application of the rapid leaf A–Ci response (RACiR) technique: examples from evergreen broadleaved species - Quanhong Lin; Di Tian; Changti Zhao; Bin Wang; Zhengbing Yan; Benjamin D. Stocker; Yu’e Li; Jingyun Fang (Photosynthesis Research, 2023)

Protecting pollinators and our food supply: understanding and managing threats to pollinator health - H. Siviter; A. Fisher; B. Baer; M. J. F. Brown; I. F. Camargo; J. Cole; Y. Le Conte; B. Dorin; J. D. Evans; W. Farina; J. Fine; L. R. Fischer; et al. (Insectes Sociaux, 2023)
Global pollinator declines threaten food production and natural ecosystems. The drivers of declines are complicated and driven by numerous factors such as pesticide use, loss of habitat, rising pathogens due to commercial bee keeping and climate change. Halting and reversing pollinator declines will require a multidisciplinary approach and international cooperation. Here, we summarize 20 presentations given in the symposium ‘Protecting pollinators and our food supply: Understanding and managing threats to pollinator health’ at the 19th Congress of the International Union for the Study of Social Insects in San Diego, 2022. We then synthesize the key findings and discuss future research areas such as better understanding the impact of anthropogenic stressors on wild bees.

Synthesis and potential applications of cyclodextrin-based metal–organic frameworks: a review - Yang Xu; Ahmed K. Rashwan; Ahmed I. Osman; Eman M. Abd El-Monaem; Ahmed M. Elgarahy; Abdelazeem S. Eltaweil; Mirna Omar; Yuting Li; Abul-Hamd E. Mehanni; Wei Chen; David W. Rooney (Environmental Chemistry Letters, 2023)
Metal–organic frameworks are porous polymeric materials formed by linking metal ions with organic bridging ligands. Metal–organic frameworks are used as sensors, catalysts for organic transformations, biomass conversion, photovoltaics, electrochemical applications, gas storage and separation, and photocatalysis. Nonetheless, many actual metal–organic frameworks present limitations such as toxicity of preparation reagents and components, which make frameworks unusable for food and pharmaceutical applications. Here, we review the structure, synthesis and properties of cyclodextrin-based metal–organic frameworks that could be used in bioapplications. Synthetic methods include vapor diffusion, microwave-assisted, hydro/solvothermal, and ultrasound techniques. The vapor diffusion method can produce cyclodextrin-based metal–organic framework crystals with particle sizes ranging from 200 nm to 400 μm. Applications comprise food packaging, drug delivery, sensors, adsorbents, gas separation, and membranes. Cyclodextrin-based metal–organic frameworks showed loading efficacy of the bioactive compounds ranging from 3.29 to 97.80%.

Declining Amazon biomass due to deforestation and subsequent degradation losses exceeding gains - Dominic Fawcett; Stephen Sitch; Philippe Ciais; Jean Pierre Wigneron; Celso H. L. Silva‐Junior; Viola Heinrich; Christelle Vancutsem; Frédéric Achard; Ana Bastos; Hui Yang; Xiaojun Li; Clément Albergel; et al. (Global Change Biology, 2023)
In the Amazon, deforestation and climate change lead to increased vulnerability to forest degradation, threatening its existing carbon stocks and its capacity as a carbon sink. We use satellite L‐Band Vegetation Optical Depth (L‐VOD) data that provide an integrated (top‐down) estimate of biomass carbon to track changes over 2011–2019. Because the spatial resolution of L‐VOD is coarse (0.25°), it allows limited attribution of the observed changes. We therefore combined high‐resolution annual maps of forest cover and disturbances with biomass maps to model carbon losses (bottom‐up) from deforestation and degradation, and gains from regrowing secondary forests. We show an increase of deforestation and associated degradation losses since 2012 which greatly outweigh secondary forest gains. Degradation accounted for 40% of gross losses. After an increase in 2011, old‐growth forests show a net loss of above‐ground carbon between 2012 and 2019. The sum of component carbon fluxes in our model is consistent with the total biomass change from L‐VOD of 1.3 Pg C over 2012‐2019. Across nine Amazon countries, we found that while Brazil contains the majority of biomass stocks (64%), its losses from disturbances were disproportionately high (79% of gross losses). Our multi‐source analysis provides a pessimistic assessment of the Amazon carbon balance and highlights the urgent need to stop the recent rise of deforestation and degradation, particularly in the Brazilian Amazon.

RecruitNet : A global database of plant recruitment networks - Miguel Verdú; Jose L. Garrido; Julio M. Alcántara; Alicia Montesinos‐Navarro; Salomón Aguilar; Marcelo A. Aizen; Ali A. Al‐Namazi; Mohamed Alifriqui; David Allen; Kristina J. Anderson‐Teixeira; Cristina Armas; Jesús M. Bastida; et al. (Ecology, 2023)
Plant recruitment interactions (i.e., what recruits under what) shape the composition, diversity, and structure of plant communities. Despite the huge body of knowledge on the mechanisms underlying recruitment interactions among species, we still know little about the structure of the recruitment networks emerging in ecological communities. Modeling and analyzing the community‐level structure of plant recruitment interactions as a complex network can provide relevant information on ecological and evolutionary processes acting both at the species and ecosystem levels. We report a data set containing 143 plant recruitment networks in 23 countries across five continents, including temperate and tropical ecosystems. Each network identifies the species under which another species recruits. All networks report the number of recruits (i.e., individuals) per species. The data set includes >850,000 recruiting individuals involved in 118,411 paired interactions among 3318 vascular plant species across the globe. The cover of canopy species and open ground is also provided. Three sampling protocols were used: (1) The Recruitment Network (RN) protocol (106 networks) focuses on interactions among established plants (“canopy species”) and plants in their early stages of recruitment (“recruit species”). A series of plots was delimited within a locality, and all the individuals recruiting and their canopy species were identified; (2) The paired Canopy‐Open (pCO) protocol (26 networks) consists in locating a potential canopy plant and identifying recruiting individuals under the canopy and in a nearby open space of the same area; (3) The Georeferenced plot (GP) protocol (11 networks) consists in using information from georeferenced individual plants in large plots to infer canopy‐recruit interactions. Some networks incorporate data for both herbs and woody species, whereas others focus exclusively on woody species. The location of each study site, geographical coordinates, country, locality, responsible author, sampling dates, sampling method, and life habits of both canopy and recruit species are provided. This database will allow researchers to test ecological, biogeographical, and evolutionary hypotheses related to plant recruitment interactions. There are no copyright restrictions on the data set; please cite this data paper when using these data in publications.

Implicit satiety goals and food-related expectations predict portion size in older adults: Findings from the BAMMBE cohort - Aimee E. Pink; Li Ling Lee; Dorrain Yanwen Low; Yifan Yang; LaiGuan Zoey Fong; Alicia Yi Hui Kang; Peijia Liu; Hyejin Kim; Yulan Wang; Parasuraman Padmanabhan; Lynne Cobiac; Balázs Gulyás; et al. (Appetite, 2023)

Nondestructive and rapid method for sex identification of the tropical sea cucumber Holothuria scabra by anal swab sampling - Zixuan E; Chuhang Cheng; Feifei Wu; Chunhua Ren; Rong Chen; Yingzhu Rao; Bo Ma; Xiao Jiang; Peng Luo; Xiaomin Li; Xin Zhang; Fajun Jiang; et al. (Aquaculture, 2023)

Environmental microplastics exposure decreases antioxidant ability, perturbs gut microbial homeostasis and metabolism in chicken - Aoyun Li; Yingli Wang; Muhammad Fakhar-e-Alam Kulyar; Mudassar Iqbal; Renhao Lai; Huaisen Zhu; Kun Li (Science of The Total Environment, 2023)

Does normalization of SARS-CoV-2 concentrations by Pepper Mild Mottle Virus improve correlations and lead time between wastewater surveillance and clinical data in Alberta (Canada): comparing twelve SARS-CoV-2 normalization approaches - Rasha Maal-Bared; Yuanyuan Qiu; Qiaozhi Li; Tiejun Gao; Steve E. Hrudey; Sudha Bhavanam; Norma J. Ruecker; Erik Ellehoj; Bonita E. Lee; Xiaoli Pang (Science of The Total Environment, 2023)

In situ formed CaSO4 on waste dander biochar to inhibit the mineralization of soil organic carbon - Cheng Ji; Shuyi Yang; Ying Cheng; Lin Liu; Daohan Wang; Shujing Zhu; Tao E; Yun Li (Science of The Total Environment, 2023)

How swimming style and schooling affect the hydrodynamics of two accelerating wavy hydrofoils - Zhonglu Lin; Amneet Pal Singh Bhalla; Boyce E. Griffith; Zi Sheng; Hongquan Li; Dongfang Liang; Yu Zhang (Ocean Engineering, 2023)

Phytoplankton productivity and community structure changes in the middle Okinawa Trough since the last deglaciation - Mengna Chen; Da-Wei Li; Li Li; Gui'e Jin; Guangxue Li; Jishang Xu; Meixun Zhao (Palaeogeography, Palaeoclimatology, Palaeoecology, 2023)

A peat core Hg stable isotope reconstruction of Holocene atmospheric Hg deposition at Amsterdam Island (37.8oS) - Chuxian Li; Maxime Enrico; Oliver Magand; Beatriz F. Araujo; Gaël Le Roux; Stefan Osterwalder; Aurélien Dommergue; Yann Bertrand; Jérôme Brioude; François De Vleeschouwer; Jeroen E. Sonke (Geochimica et Cosmochimica Acta, 2023)

Fabrication of P-MoO2-Fe3O4 nanobelts for efficient overall water splitting - Zhijie Cui; Tiantian Feng; Xuehong Wang; Pengfei Guo; Wenpin Wang; Mei-E Yue; Zhongcheng Li (Fuel, 2023)

Investigation of the heat release rate and particle generation during fixed bed gasification of sweet sorghum stalk - Francis O. Olanrewaju; Gordon E. Andrews; Hu Li; Herodotos N. Phylaktou; Bintu G. Mustafa; Miss H. Mat Kiah (Fuel, 2023)

Multi-scale deterioration of physical and mechanical properties of argillaceous siltstone under cyclic wetting-drying of Yangtze River water - Wenmin Yao; Changdong Li; Qirui Ke; Yibo Fan; Bingchen Li; Hongbin Zhan; Robert E. Criss (Engineering Geology, 2023)

Recovery from persistent nutrient-N limitation following the Permian–Triassic mass extinction - Yong Du; Huyue Song; Stephen E. Grasby; Teng Xing; Haijun Song; Li Tian; Daoliang Chu; Yuyang Wu; Jacopo Dal Corso; Thomas J. Algeo; Jinnan Tong (Earth and Planetary Science Letters, 2023)

Toughing epoxy nanocomposites with graphene-encapsulated liquid metal framework - Da Li; E Peng; Fei Lu; Baolong Wang; Yibo Shen; Pengxiang Liu; Li Liu; Yudong Huang; Zhen Hu (Chemical Engineering Journal, 2023)

Ethane-driven chromate and nitrate bioreductions in a membrane biofilm reactor - Zifang Chi; Shijie Ju; Wenjing Wang; Huai Li; Yi-Hao Luo; Bruce E. Rittmann (Chemical Engineering Journal, 2023)

Tumor cell-derived microparticles packaging monocarboxylate transporter4 inhibitor fluvastatin suppress lung adenocarcinoma via tumor microenvironment remodeling and improve chemotherapy - Wenjuan Chen; Qi Tan; Mengfei Guo; Tingting Liao; Yumei Li; Zhengrong Yin; E. Zhou; Jingjing Deng; Minglei Li; Zimo Yang; Jiangbin Chen; Jiaping Chen; et al. (Chemical Engineering Journal, 2023)

Temperature tolerant all-solid-state touch panel with high stretchablity, transparency and self-healing ability - Zhenglin Chen; Fang Li; Likun Zhang; Zhengyang Lei; Canhui Yang; Chufan Xiao; Lijin Lian; Xi Yuan; Gul Ijaz; Jia'e Yang; Zijun Lin; Yunfeng He; et al. (Chemical Engineering Journal, 2023)

Impact of social reward on the evolution of cooperation in voluntary prisoner’s dilemma - Yu’e Wu; Jing Jing Li (BioSystems, 2023)

Genome‐wide SNPs confirm plumage polymorphism and hybridisation within a Cyornis flycatcher species complex - Elize Y. X. Ng; Siqi Li; Dezhi Zhang; Kritika M. Garg; Gang Song; Jonathan Martinez; Le Manh Hung; Vuong Tan Tu; Jérôme Fuchs; Lu Dong; Urban Olsson; Yuan Huang; et al. (Zoologica Scripta, 2023)
Morphology has been a leading taxonomic guiding light to systematists for the last couple of hundred years. However, the genetic and – more recently – genomic revolution have produced numerous demonstrations of erroneous classifications that were based on labile morphological traits. We used thousands of genome‐wide markers to shed light on evolutionary dynamics in a confusing and taxonomically obscure group of Asian Cyornis flycatchers. Using genomic data, we corroborated recent findings based on three mitochrondrial and five nuclear genes that the two taxa hainanus and klossi which were previously treated as separate species ( Cyornis hainanus and Cyornis rubeculoides klossi , respectively) are genomically homogeneous and form a single species, C. hainanus . We also uncovered a novel case of interbreeding between C. hainanus and a non‐sister species, C. glaucicomans , illustrating these flycatchers' ability to hybridise in marginal situations even after substantial times of divergence. Our study illustrates how genome‐wide loci can shed light on complicated taxonomic problems, resulting in a better integration of phenotypic and genotypic data.

Experimental temperatures shape host microbiome diversity and composition - Jingdi Li; Kieran A. Bates; Kim L. Hoang; Tobias E. Hector; Sarah C. L. Knowles; Kayla C. King (Global Change Biology, 2023)
Global climate change has led to more extreme thermal events. Plants and animals harbour diverse microbial communities, which may be vital for their physiological performance and help them survive stressful climatic conditions. The extent to which microbiome communities change in response to warming or cooling may be important for predicting host performance under global change. Using a meta‐analysis of 1377 microbiomes from 43 terrestrial and aquatic species, we found a decrease in the amplicon sequence variant‐level microbiome phylogenetic diversity and alteration of microbiome composition under both experimental warming and cooling. Microbiome beta dispersion was not affected by temperature changes. We showed that the host habitat and experimental factors affected microbiome diversity and composition more than host biological traits. In particular, aquatic organisms—especially in marine habitats—experienced a greater depletion in microbiome diversity under cold conditions, compared to terrestrial hosts. Exposure involving a sudden long and static temperature shift was associated with microbiome diversity loss, but this reduction was attenuated by prior‐experimental lab acclimation or when a ramped regime (i.e., warming) was used. Microbial differential abundance and co‐occurrence network analyses revealed several potential indicator bacterial classes for hosts in heated environments and on different biome levels. Overall, our findings improve our understanding on the impact of global temperature changes on animal and plant microbiome structures across a diverse range of habitats. The next step is to link these changes to measures of host fitness, as well as microbial community functions, to determine whether microbiomes can buffer some species against a more thermally variable and extreme world.

Ginsenoside Rg1 regulates thiram-induced chondrocytes’ apoptosis and angiogenesis in broiler chickens - Huaisen Zhu; Muhammad Fakhar-e-Alam Kulyar; Yanmei Ding; Wangyuan Yao; Quan Mo; Jiakui Li (Environmental Science and Pollution Research, 2022)

Cognitive Intra-individual Variability in HIV: an Integrative Review - David E. Vance; Victor A. Del Bene; Jennifer Sandson Frank; Rebecca Billings; Kristen Triebel; Alison Buchholz; Leah H. Rubin; Steven Paul Woods; Wei Li; Pariya L. Fazeli (Neuropsychology Review, 2022)

Subjective Cognitive Decline: Level of Risk for Future Dementia and Mild Cognitive Impairment, a Meta-Analysis of Longitudinal Studies - Kerryn E. Pike; Marina G. Cavuoto; Lily Li; Bradley J. Wright; Glynda J. Kinsella (Neuropsychology Review, 2022)

The nature of spatial variability of four soil chemical properties and the implications for soil sampling - R. C. Hayes; M. Rohan; G. D. Li; S. E. Orgill; G. J. Poile; A. A. Oates; M. K. Conyers (Journal of Soils and Sediments, 2022)

2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Sergey V. Alkhovsky; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Martina Bandte; Martin Beer; Nicolas Bejerman; Éric Bergeron; et al. (Archives of Virology, 2022)

Electronic cigarette vaping with aged coils causes acute lung injury in mice - Shunsaku Goto; Robert M. H. Grange; Riccardo Pinciroli; Ivy A. Rosales; Rebecca Li; Sophie L. Boerboom; Katrina F. Ostrom; Eizo Marutani; Hatus V. Wanderley; Aranya Bagchi; Robert B. Colvin; Lorenzo Berra; et al. (Archives of Toxicology, 2022)

Characteristics of antibiotic resistance gene distribution in rainfall runoff and combined sewer overflow - Xin-rong Pan; Lei Chen; Li-ping Zhang; Jian-e Zuo (Environmental Science and Pollution Research, 2022)

Group-specific functional patterns of mitochondrion-related organelles shed light on their multiple transitions from mitochondria in ciliated protists - Zhicheng Chen; Jia Li; Dayana E. Salas-Leiva; Miaoying Chen; Shilong Chen; Senru Li; Yanyan Wu; Zhenzhen Yi (Marine Life Science & Technology, 2022)

Usher syndrome type IV: clinically and molecularly confirmed by novel ARSG variants - Hedwig M. Velde; Janine Reurink; Sebastian Held; Catherina H. Z. Li; Suzanne Yzer; Jaap Oostrik; Jack Weeda; Lonneke Haer-Wigman; Helger G. Yntema; Susanne Roosing; Laurenz Pauleikhoff; Clemens Lange; et al. (Human Genetics, 2022)
Usher syndrome (USH) is an autosomal recessively inherited disease characterized by sensorineural hearing loss (SNHL) and retinitis pigmentosa (RP) with or without vestibular dysfunction. It is highly heterogeneous both clinically and genetically. Recently, variants in the arylsulfatase G ( ARSG ) gene have been reported to underlie USH type IV. This distinct type of USH is characterized by late-onset RP with predominantly pericentral and macular changes, and late onset SNHL without vestibular dysfunction. In this study, we describe the USH type IV phenotype in three unrelated subjects. We identified three novel pathogenic variants, two novel likely pathogenic variants, and one previously described pathogenic variant in ARSG . Functional experiments indicated a loss of sulfatase activity of the mutant proteins. Our findings confirm that ARSG variants cause the newly defined USH type IV and support the proposed extension of the phenotypic USH classification.

Oxygen-containing groups in cellulose and lignin biochar: their roles in U(VI) adsorption - Yongzhong Feng; Xiaoyi Qiu; Zhuolin Tao; Zhengyang E; Jiayu Song; Yaqiong Dong; Jianjun Liang; Ping Li; Qiaohui Fan (Environmental Science and Pollution Research, 2022)

Mesoscale oceanographic features drive divergent patterns in connectivity for co‐occurring estuarine portunid crabs - Daniel E. Hewitt; Hayden T. Schilling; Roshan Hanamseth; Jason D. Everett; Junde Li; Moninya Roughan; Daniel D. Johnson; Iain M. Suthers; Matthew D. Taylor (Fisheries Oceanography, 2022)
Larval dispersal and connectivity have important implications for fisheries management, especially for species with life cycles influenced by ocean boundary currents. Giant Mud Crab ( Scylla serrata ) and Blue Swimmer Crab ( Portunus armatus ) are two estuarine portunid crabs (Family: Portunidae) that support significant commercial and recreational harvest in eastern Australia. Giant Mud Crab migrate to coastal waters to spawn, and while Blue Swimmer Crab spawn primarily within estuaries they occasionally migrate to coastal waters to spawn, followed by larval dispersal in the East Australian Current (EAC). Here, we coupled a high‐resolution oceanographic model with a Lagrangian particle tracking framework to simulate larval dispersal and determine the extent of population connectivity in this region. Our simulations indicate broad‐scale connectivity (~40–400 km), characterised by high inter‐estuary connectivity. Overall, our results suggest a north‐to‐south source‐sink structure for both species, with contributions of particles from the north ranging from 51% to 99%. Recruitment to a given estuary is dependent on the proximity of mesoscale oceanographic features of the EAC. Most notably, the EAC separation acts as a barrier to recruitment between spawning and settlement to the north/south of this region. This significantly limits interjurisdictional connectivity for these species, especially Blue Swimmer Crab, likely due to a shorter pelagic larval duration than Giant Mud Crab. Our results provide evidence to inform the assessment and management of these species.

Improved Growth and High Inheritance of Melanocortin-4 Receptor (mc4r) Mutation in CRISPR/Cas-9 Gene-Edited Channel Catfish, Ictalurus punctatus - Michael Coogan; Veronica Alston; Baofeng Su; Karim Khalil; Ahmed Elaswad; Mohd Khan; Andrew Johnson; De Xing; Shangjia Li; Jinhai Wang; Rhoda M. C. Simora; Cuiyu Lu; et al. (Marine Biotechnology, 2022)

Effect of posaconazole on the concentration of intravenous and oral cyclosporine in patients undergoing hematopoietic stem cell transplantation - Li-E Zhu; Hui-Ping Huang; Yi-Peng Cai; Yan Wang; Bao-Hua Xu; Mao-Bai Liu; Xue-Mei Wu (European Journal of Clinical Pharmacology, 2022)

Environmental filtering in the dry season and spatial structuring in the wet: different fish community assembly rules revealed in a large subtropical floodplain lake - Xiao Chen; Zhengfei Li; Pál Boda; Izaias Médice Fernandes; Zhicai Xie; E. Zhang (Environmental Science and Pollution Research, 2022)

Spatial patterns of extreme precipitation and their changes under ~ 2 °C global warming: a large-ensemble study of the western USA - David E. Rupp; Linnia R. Hawkins; Sihan Li; Matthew Koszuta; Nicholas Siler (Climate Dynamics, 2022)

Improving the combined GNSS/INS positioning by using tightly integrated RTK - Bofeng Li; Guang’e Chen (GPS Solutions, 2022)

Evaluation of short-term probabilistic eruption forecasting at Whakaari, New Zealand - D. E. Dempsey; A. W. Kempa-Liehr; A. Ardid; A. Li; S. Orenia; J. Singh; A. J. Tyler; S. J. Cronin (Bulletin of Volcanology, 2022)
Phreatic explosions at volcanoes are difficult to forecast but can be locally devastating, as illustrated by the deadly 2019 Whakaari (New Zealand) eruption. Quantifying eruption likelihood is essential for risk calculations that underpin volcano access decisions and disaster response. But estimating eruption probabilities is notoriously difficult for sudden onset eruptions. Here, we describe two retrospectively developed models for short-term (48 h) probabilistic forecasting of phreatic eruptions at Whakaari. The models are based on a pseudo-prospective analysis of seven Whakaari eruptions whose precursors were identified by time series feature engineering of continuous seismic data. The first model, an optimized warning system, could anticipate six out of seven eruptions at the cost of 14 warning days each year. While a warning is in effect, the probability of eruption is about 8% in 48 h, which is about 126 times higher than outside the warning. The second model used isotonic calibration to translate the output of the forecast model onto a probability scale. When applied pseudo-prospectively in the 48 h prior to the December 2019 eruption, it indicated an eruption probability up to 400 times higher than the background. Finally, we quantified the accuracy of these seismic data-driven forecasts, alongside an observatory expert elicitation that used multiple data sources. To do this, we used a forecast skill score that was benchmarked against the average rate of eruptions at Whakaari between 2011 and 2019. This exercise highlights the conditions under which the three different forecasting approaches perform well and where potential improvements could be made.

Local and remote forcing on the interannual variations of the sedimentary δ15N in Santa Barbara Basin during the past 80 years - Hanyue Xu; Da-Wei Li; Hong-Chun Li; Meixun Zhao; William M. Berelson; Gui’e Jin; Li Li; Satabdi Misra (Frontiers in Marine Science, 2022)
Sedimentary nitrogen isotope (δ 15 N sed ) in Santa Barbara Basin (SBB) has been mostly interpreted as the record of the eastern tropical North Pacific (ETNP) intermediate water denitrification process. Nevertheless, debate remains regarding sources and control mechanisms of δ 15 N sed signal in SBB. Multi-proxy analyses including δ 15 N sed , total organic carbon (TOC), total nitrogen (TN), C/N ratio, and marine biomarkers were performed on a 46-cm sediment core (SBB-190629) collected from SBB in 2019. The core was dated with varve counting and 210 Pb dating method, showing a depositional history of 1938–2019 CE with a sedimentation rate of 0.564 cm/year. The findings show that the δ 15 N sed record (at ~0.25-year resolution) ranges from 6.24‰ to 7.43‰, which was affected by both local and remote forcing. The long-term variations of the SBB δ 15 N sed signature show a general decreasing trend from 1940 to the late 1980s, low values during 1980~2000, and an increase afterward, which is thought to reflect changes in ETNP denitrification induced by the strength of tropical trade winds. Our results also reveal a series of abrupt annual to multiannual changes, superimposed on the long-term variation mentioned above. The SBB local δ 15 N signal (Δδ 15 N SBB ) is accessed by using the deviation from the mean δ 15 N (Δδ 15 N) of SBB-190629 to subtract the Δδ 15 N of the ETNP. The Δδ 15 N SBB record compares well with redox-sensitive proxies (Re/Mo ratio and C 29 stanol/stenol ratio) from the SBB bottom water and with the OC marine content calculated based on the C/N ratio mixing model, indicating that the Δδ 15 N SBB is mainly controlled by bottom water denitrification, which was induced by the change of upwelling intensity and marine productivity. Since various climatic factors (e.g., El Niño–Southern Oscillation (ENSO), Pacific Decadal Oscillation (PDO), and North Pacific Gyre Oscillation (NPGO)) have different impacts on the upwelling intensity (hence the marine productivity and denitrification) in SBB on different timescales, the influence of combined climatic factors on SBB denitrification is time dependent.

Innovating transcriptomics for practitioners in freshwater fish management and conservation: best practices across diverse resource-sector users - C. A. D. Semeniuk; K. M. Jeffries; T. Li; C. M. Bettles; S. J. Cooke; B. A. Dufour; E. A. Halfyard; J. W. Heath; K. Keeshig; N. E. Mandrak; A. J. Muir; L. Postma; et al. (Reviews in Fish Biology and Fisheries, 2022)

Triphenylpyrazoline ketone chlorophenols as potential candidate compounds against Parkinson’s disease: design, synthesis, and biological evaluation - Ning Ning Cheng; Le Hua Zhang; Rui Ge; Xiu E. Feng; Qing Shan Li (Medicinal Chemistry Research, 2022)

Ambiguity resolution for smartphone GNSS precise positioning: effect factors and performance - Bofeng Li; Weikai Miao; Guang’e Chen; Zhong Li (Journal of Geodesy, 2022)

Short-term deformation characteristics, displacement prediction, and kinematic mechanism of Baijiabao landslide based on updated monitoring data - Wenmin Yao; Changdong Li; Yuancheng Guo; Robert E. Criss; Qingjun Zuo; Hongbin Zhan (Bulletin of Engineering Geology and the Environment, 2022)

Effect of co-fermentation system with isolated new yeasts on soymilk: microbiological, physicochemical, rheological, aromatic, and sensory characterizations - Sameh A. Korma; Li Li; Mohamed Ghamry; Qiyang Zhou; Peipei An; Khaled A. E. Abdrabo; Muhammad Faisal Manzoor; Abdur Rehman; Sobia Niazi; Ilaria Cacciotti (Brazilian Journal of Microbiology, 2022)

Tallo: A global tree allometry and crown architecture database - Tommaso Jucker; Fabian Jörg Fischer; Jérôme Chave; David A. Coomes; John Caspersen; Arshad Ali; Grace Jopaul Loubota Panzou; Ted R. Feldpausch; Daniel Falster; Vladimir A. Usoltsev; Stephen Adu‐Bredu; Luciana F. Alves; et al. (Global Change Biology, 2022)
Data capturing multiple axes of tree size and shape, such as a tree's stem diameter, height and crown size, underpin a wide range of ecological research—from developing and testing theory on forest structure and dynamics, to estimating forest carbon stocks and their uncertainties, and integrating remote sensing imagery into forest monitoring programmes. However, these data can be surprisingly hard to come by, particularly for certain regions of the world and for specific taxonomic groups, posing a real barrier to progress in these fields. To overcome this challenge, we developed the Tallo database, a collection of 498,838 georeferenced and taxonomically standardized records of individual trees for which stem diameter, height and/or crown radius have been measured. These data were collected at 61,856 globally distributed sites, spanning all major forested and non‐forested biomes. The majority of trees in the database are identified to species (88%), and collectively Tallo includes data for 5163 species distributed across 1453 genera and 187 plant families. The database is publicly archived under a CC‐BY 4.0 licence and can be access from: https://doi.org/10.5281/zenodo.6637599 . To demonstrate its value, here we present three case studies that highlight how the Tallo database can be used to address a range of theoretical and applied questions in ecology—from testing the predictions of metabolic scaling theory, to exploring the limits of tree allometric plasticity along environmental gradients and modelling global variation in maximum attainable tree height. In doing so, we provide a key resource for field ecologists, remote sensing researchers and the modelling community working together to better understand the role that trees play in regulating the terrestrial carbon cycle.

Comparison of different ensemble precipitation forecast system evaluation, integration and hydrological applications - Yehai Tang; Qiang Wu; Shan-e-hyder Soomro; Xiang Li; Yue Sun; Caihong Hu (Acta Geophysica, 2022)

The genetic basis for panicle trait variation in switchgrass (Panicum virgatum) - Li Zhang; Alice MacQueen; Xiaoyu Weng; Kathrine D. Behrman; Jason Bonnette; John L. Reilley; Francis M. Rouquette; Philip A. Fay; Yanqi Wu; Felix B. Fritschi; Robert B. Mitchell; David B. Lowry; et al. (Theoretical and Applied Genetics, 2022)
Key message We investigate the genetic basis of panicle architecture in switchgrass in two mapping populations across a latitudinal gradient, and find many stable, repeatable genetic effects and limited genetic interactions with the environment. Abstract Grass species exhibit large diversity in panicle architecture influenced by genes, the environment, and their interaction. The genetic study of panicle architecture in perennial grasses is limited. In this study, we evaluate the genetic basis of panicle architecture including panicle length, primary branching number, and secondary branching number in an outcrossed switchgrass QTL population grown across ten field sites in the central USA through multi-environment mixed QTL analysis. We also evaluate genetic effects in a diversity panel of switchgrass grown at three of the ten field sites using genome-wide association (GWAS) and multivariate adaptive shrinkage. Furthermore, we search for candidate genes underlying panicle traits in both of these independent mapping populations. Overall, 18 QTL were detected in the QTL mapping population for the three panicle traits, and 146 unlinked genomic regions in the diversity panel affected one or more panicle trait. Twelve of the QTL exhibited consistent effects (i.e., no QTL by environment interactions or no QTL × E), and most (four of six) of the effects with QTL × E exhibited site-specific effects. Most (59.3%) significant partially linked diversity panel SNPs had significant effects in all panicle traits and all field sites and showed pervasive pleiotropy and limited environment interactions. Panicle QTL co-localized with significant SNPs found using GWAS, providing additional power to distinguish between true and false associations in the diversity panel.

REGγ drives Lgr5+ stem cells to potentiate radiation induced intestinal regeneration - Xiangzhan Zhu; Minglei Yang; Zaijun Lin; Solomon Kibreab Mael; Ya Li; Lili Zhang; Yaqi Kong; Yaodong Zhang; Yuping Ren; Jianhui Li; Zimeng Wang; Ying Zhang; et al. (Science China Life Sciences, 2022)

Generalist endophyte Phomopsis liquidambaris colonization of Oryza sativa L. promotes plant growth under nitrogen starvation - Jun Zhou; Peng-Wei Huang; Xin Li; Fabián E. Vaistij; Chuan-Chao Dai (Plant Molecular Biology, 2022)

Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment - Jiehui Jiang; Can Sheng; Guanqun Chen; Chunhua Liu; Shichen Jin; Lanlan Li; Xueyan Jiang; Ying Han; Michael W. Weiner; Paul Aisen; Ronald Petersen; Clifford R. Jack; et al. (GeroScience, 2022)

Assessing the joint effects of brain aging and gut microbiota on the risks of psychiatric disorders - Huijie Zhang; Li Liu; Shiqiang Cheng; Yumeng Jia; Yan Wen; Xuena Yang; Peilin Meng; Chun’e Li; Chuyu Pan; Yujing Chen; Zhen Zhang; Jingxi Zhang; et al. (Brain Imaging and Behavior, 2022)

Wilderness forms and their implications for global environmental policy and conservation - Katharina‐Victoria Pérez‐Hämmerle; Katie Moon; Rubén Venegas‐Li; Sean Maxwell; Jeremy S. Simmonds; Oscar Venter; Stephen T. Garnett; Hugh P. Possingham; James E. M. Watson (Conservation Biology, 2022)
With the intention of securing industry‐free land and seascapes, protecting wilderness entered international policy as a formal target for the first time in the zero draft of the Post‐2020 Global Biodiversity Framework under the Convention on Biological Diversity. Given this increased prominence in international policy, it is timely to consider the extent to which the construct of wilderness supports global conservation objectives. We evaluated the construct by overlaying recently updated cumulative human pressure maps that offer a global‐scale delineation of industry‐free land as wilderness with maps of carbon stock, species richness, and ground travel time from urban centers. Wilderness areas took variable forms in relation to carbon stock, species richness, and proximity to urban centers, where 10% of wilderness areas represented high carbon and species richness, 20% low carbon and species richness, and 3% high levels of remoteness (>48 h), carbon, and species richness. Approximately 35% of all remaining wilderness in 2013 was accessible in

Electrospun nanofibers food packaging: trends and applications in food systems - Dur E. Sameen; Saeed Ahmed; Rui Lu; Rui Li; Jianwu Dai; Wen Qin; Qing Zhang; Suqing Li; Yaowen Liu (Critical Reviews in Food Science and Nutrition, 2022)

Sensor placement and seismic response reconstruction for structural health monitoring using a deep neural network - Yuxin Pan; Carlos E. Ventura; Teng Li (Bulletin of Earthquake Engineering, 2022)

Anthropocene Geochemical and Technological Signatures of an Experimental Landfill Bioreactor in the Central Valley of California - Gry H. Barfod; Reinhard Seiser; Ramin Yazdani; Li Wang; Charles E. Lesher; Bryan M. Jenkins; Peter Thy (Anthropocene Science, 2022)
The geochemical signatures of a 12-year-old experimental bioreactor at a California landfill are used to identify elemental concentrations and ratios that characterize the landfill and relate it to the age and state of technology of the deposited waste. The bioreactor was constructed and sealed with a synthetic liner during 2001–2002 and operated and monitored as an anaerobic digester to enhance methane production. In 2013, the bioreactor was sampled and trace element concentrations of the extracted fine fractions were determined. The concentrations normalized to a regional soil composition, reveal systematic peaks for transition metals, alkali metals, heavy metals, and various metalloids and non-metals. A group of potential solder elements (Cu, Zn, Cd, In, Sn, Pb, Bi, and Sb) shows moderate to strong co-variations and is largely attributed to household electronic components and other similar products, while elements that correlated well with rare-earth and other elements are related to the diluting effect of a soil component used as cover. Batteries show modest to little effects on the overall concentrations. Circulating fluids (recycled leachate) in the controlled reactor did not completely redistribute and homogenize the elemental signatures within the time frame of the bioreactor. It is concluded that the present experimental landfill defines an Anthropocene marker identifiable by building material (plaster), PVC plastic, and household electronic components (Pb–Sn solder). These marker elements and ratios are variably diluted by soil components identified by alkali metals, rare-earths, and high field-strength elements (Hf, Zr, Nb, and Ta).

Evidence of interactions between sharks and Indo‐Pacific humpback dolphins ( Sousa chinensis ) in the northern South China Sea - Agathe Serres; Wenzhi Lin; Eric E. G. Clua; Mingli Lin; Mingming Liu; Songhai Li (Marine Mammal Science, 2022)

Diversity and Structure of Demersal Fish Community Over the Northern Slope in the South China Sea - Jun Zhang; Kui Zhang; Yan-e Jiang; Yuan-jie Li; Jiang-tao Fan; Wen-ming Yu; Zuo-zhi Chen (Frontiers in Marine Science, 2022)
Three bottom trawl surveys over the northern continental slope in the South China Sea (18°50′–20°40′N, 112°50′–115°10′E) were carried out, in June 2015, March 2017 and September 2018, to investigate species composition, biodiversity and community structure of demersal fish. Surveys in 2015, 2017 and 2018 captured 97 fish species (representing 77 genera, 52 families, 26 orders), 108 fish species (representing 84 genera, 61 families, 19 orders) and 126 fish species (representing 105 genera, 74 families, 25 orders), respectively. Three surveys captured a total of 252 fish species, representing 164 genera, 97 families, 30 orders. Perciformes dominated. Species richness in station linking shallow continental shelf with deep slope was the lowest among stations. In three surveys, 16 species occurred in the catches of three surveys, accounting for 6.35% of all species. Species replacement rate between stations showed a significant linear relationship with the depth difference and latitude difference. Margalef’s species richness index ( D ), Shannon–Weiner diversity index ( H’ ) and Pielou’s evenness index ( J’ ) among stations ranged 2.65–6.74, 1.02–4.15 and 0.28–1.14, respectively. Differences of D , H ’ and J ’ were insignificant among seasons. There were significant positive linear relations between H’ and J’ and latitude. D , H’ and J’ decreased with increasing sampling depth, however the relations were not significant. Based on multivariate statistical analysis, fish community at species level was divided into five groups with average dissimilarities of 95.69%–99.96%. In terms of genus and family, average dissimilarities among groups were more than 88.11% and 82.69%. There were significant differences in species composition between depths, but no significant differences between seasons and temperatures, as well as in genus and family composition.

Probiotic Potential of Bacillus licheniformis and Bacillus pumilus Isolated from Tibetan Yaks, China - Zhibo Zeng; Jiabin Zhang; Yan Li; Kewei Li; Saisai Gong; Feiran Li; Pengpeng Wang; Mudassar Iqbal; Muhammad Fakhar-e-Alam Kulyar; Jiakui Li (Probiotics and Antimicrobial Proteins, 2022)

Aberrant Immunoglobulin G Glycosylation in Multiple Sclerosis - Peter G. E. Kennedy; Michael Graner; Tiffany Pointon; Xiaomeng Li; Kayo Tanimoto; Kathryn Dennison; Gina Im; Anthony Fringuello; Wenbo Zhou; Arin Graner; Stefan Sillau; Timothy Vollmer; et al. (Journal of Neuroimmune Pharmacology, 2022)

Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume - Lidija Milicic; Michael Vacher; Tenielle Porter; Vincent Doré; Samantha C. Burnham; Pierrick Bourgeat; Rosita Shishegar; James Doecke; Nicola J. Armstrong; Rick Tankard; Paul Maruff; Colin L. Masters; et al. (GeroScience, 2022)
The concept of age acceleration, the difference between biological age and chronological age, is of growing interest, particularly with respect to age-related disorders, such as Alzheimer’s Disease (AD). Whilst studies have reported associations with AD risk and related phenotypes, there remains a lack of consensus on these associations. Here we aimed to comprehensively investigate the relationship between five recognised measures of age acceleration, based on DNA methylation patterns (DNAm age), and cross-sectional and longitudinal cognition and AD-related neuroimaging phenotypes (volumetric MRI and Amyloid-β PET) in the Australian Imaging, Biomarkers and Lifestyle (AIBL) and the Alzheimer’s Disease Neuroimaging Initiative (ADNI). Significant associations were observed between age acceleration using the Hannum epigenetic clock and cross-sectional hippocampal volume in AIBL and replicated in ADNI. In AIBL, several other findings were observed cross-sectionally, including a significant association between hippocampal volume and the Hannum and Phenoage epigenetic clocks. Further, significant associations were also observed between hippocampal volume and the Zhang and Phenoage epigenetic clocks within Amyloid-β positive individuals. However, these were not validated within the ADNI cohort. No associations between age acceleration and other Alzheimer’s disease-related phenotypes, including measures of cognition or brain Amyloid-β burden, were observed, and there was no association with longitudinal change in any phenotype. This study presents a link between age acceleration, as determined using DNA methylation, and hippocampal volume that was statistically significant across two highly characterised cohorts. The results presented in this study contribute to a growing literature that supports the role of epigenetic modifications in ageing and AD-related phenotypes.

Investigating the combination of plasma amyloid-beta and geroscience biomarkers on the incidence of clinically meaningful cognitive decline in older adults - Wan-Hsuan Lu; Kelly Virecoulon Giudici; John E. Morley; Sophie Guyonnet; Angelo Parini; Geetika Aggarwal; Andrew D. Nguyen; Yan Li; Randall J. Bateman; Bruno Vellas; Philipe de Souto Barreto; Bruno Vellas; et al. (GeroScience, 2022)

Prediction of disability-free survival in healthy older people - Johannes Tobias Neumann; Le T. P. Thao; Anne M. Murray; Emily Callander; Prudence R. Carr; Mark R. Nelson; Rory Wolfe; Robyn L. Woods; Christopher M. Reid; Raj C. Shah; Anne B. Newman; Jeff D. Williamson; et al. (GeroScience, 2022)
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disability-free survival outcome was defined as absence of dementia, persistent disability or death. Selection of potential predictors from amongst 25 biomedical, psychosocial and lifestyle variables including recognized geriatric risk factors, utilizing a machine-learning approach. Separate models were developed for men and women. The selected predictors were evaluated in a multivariable Cox proportional hazards model and validated internally by bootstrapping. We included 19,114 Australian and US participants aged ≥65 years (median 74 years, IQR 71.6–77.7). Common predictors of a worse prognosis in both sexes included higher age, lower Modified Mini-Mental State Examination score, lower gait speed, lower grip strength and abnormal (low or elevated) body mass index. Additional risk factors for men included current smoking, and abnormal eGFR. In women, diabetes and depression were additional predictors. The biased-corrected areas under the receiver operating characteristic curves for the final prognostic models at 5 years were 0.72 for men and 0.75 for women. Final models showed good calibration between the observed and predicted risks. We developed a prediction model in which age, cognitive function and gait speed were the strongest predictors of disability-free survival in healthy older people. Trial registration Clinicaltrials.gov (NCT01038583)

Correction to: Pterocarpus marsupium extract extends replicative lifespan in budding yeast - Mitchell B. Lee; Michael G. Kiflezghi; Mitsuhiro Tsuchiya; Brian Wasko; Daniel T. Carr; Priya A. Uppal; Katherine A. Grayden; Yordanos C. Elala; Tu Anh Nguyen; Jesse Wang; Priya Rastogi; Sunny Nguyen; et al. (GeroScience, 2022)

Correction to: The role of human-induced climate change in heavy rainfall events such as the one associated with Typhoon Hagibis - Sihan Li; Friederike E. L. Otto (Climatic Change, 2022)

Correction to: Connecting the human microbiome and pancreatic cancer - Rachel E. Sexton; Md Hafz Uddin; Sahar Bannoura; Husain Yar Khan; Yousef Mzannar; Yiwei Li; Amro Aboukameel; Mohammad Najeeb Al-Hallak; Bayan Al-Share; Amr Mohamed; Misako Nagasaka; Bassel El-Rayes; et al. (Cancer and Metastasis Reviews, 2022)

Connecting the Human Microbiome and Pancreatic Cancer - Rachel E. Sexton; Md Hafiz Uddin; Sahar Bannoura; Husain Yar Khan; Yousef Mzannar; Yiwei Li; Amro Aboukameel; Mohammad Najeeb Al-Hallak; Bayan Al-Share; Amr Mohamed; Misako Nagasaka; Bassel El-Rayes; et al. (Cancer and Metastasis Reviews, 2022)

An adaptive data cleaning framework: a case study of the water quality monitoring system in China - Zeng Chen; Peng Jiang; Jun Liu; Song Zheng; Zhenyu Shan; Zhihua Li; Huan Xu; Igor V. Bychkov; Alexei E. Hmelnov (Hydrological Sciences Journal, 2022)

Four new triterpene glucosides from Salacia cochinchinensis Lour - Lu Gao; Li-Kun Duan; Jin-E Feng; Yun-Tao Jiang; Jun Gao; Jun-Ting Fan; Rong Dai; Zhi-Yong Jiang (Natural Product Research, 2022)

River Flood Susceptibility and Basin Maturity Analyzed Using a Coupled Approach of Geo-morphometric Parameters and SWAT Model - Shan-e-hyder Soomro; Caihong Hu; Muhammad Waseem Boota; Zubair Ahmed; Liu Chengshuai; Han Zhenyue; Li Xiang; Mairaj Hyder Alias Aamir Soomro (Water Resources Management, 2022)

Immunostimulatory effect of quaternary degree and acetyl group of quaternized chitosan on macrophages RAW 264.7 - Xiaomin Li; Rong’e Xing; Chaojie Xu; Song Liu; Yukun Qin; Kecheng Li; Huahua Yu; Pengcheng Li (Journal of Oceanology and Limnology, 2022)

Impact of land use on surface water quality: a case study of active agriculturally disturbed basin in China - L. Zhang; X. Liu; H. Wei; C. Yang; E. Li; Z. Wang (International Journal of Environmental Science and Technology, 2022)

Waste rocks from the industrial mining process: hazard metals stabilization behavior evaluating and reusing as construction materials - E. Li; H. Chen; F. Huang; L. Zhou; Z. Yu (International Journal of Environmental Science and Technology, 2022)

The role of human-induced climate change in heavy rainfall events such as the one associated with Typhoon Hagibis - Sihan Li; Friederike E. L. Otto (Climatic Change, 2022)
Around October 12, 2019, torrential rainfall from Typhoon Hagibis caused large-scale flooding in a large area around the metropole region of Tokyo leading to large-scale destruction including losses of lives, livelihoods, and economic losses of well over $10 bn US dollars. In this paper we use a multi-method probabilistic event attribution framework to assess the role of human-induced climate change in the heavy rainfall event responsible for a large proportion of the damages. Combining different observational datasets and various climate model simulations, we find an increase in the likelihood of such an event to occur of 15–150%. We use this assessment and the calculated fraction of attributable risk (FAR) to further estimate the economic costs attributable to anthropogenic climate change based on the insured economic losses. Our conservative estimate is that ~$4bn of the damages due to the extreme heavy rainfall associated with Typhoon Hagibis are due to human-induced climate change.

Research progress on antimicrobial materials for food packaging - Saeed Ahmed; Dur E. Sameen; Rui Lu; Rui Li; Jianwu Dai; Wen Qin; Yaowen Liu (Critical Reviews in Food Science and Nutrition, 2022)

Association between antidepressant use and second breast cancer event after ductal carcinoma in situ diagnosis: a nested case–control study - Elizabeth T. Mansi; Kathleen E. Malone; Mei-Tzu Tang; Nicole C. Loroña; Christopher I. Li (Cancer Causes & Control, 2022)

Vertical community patterns of Labyrinthulomycetes protists reveal their potential importance in the oceanic biological pump - Mohan Bai; Ningdong Xie; Yaodong He; Jiaqian Li; Jackie L. Collier; Dana E. Hunt; Zackary I. Johnson; Nianzhi Jiao; Guangyi Wang (Environmental Microbiology, 2022)
Summary The biological pump plays a vital role in exporting organic particles into the deep ocean for long‐term carbon sequestration. However, much remains unknown about some of its key microbial players. In this study, Labyrinthulomycetes protists (LP) were used to understand the significance of heterotrophic microeukaryotes in the transport of particulate organic matter from the surface to the dark ocean. Unlike the sharp vertical decrease of prokaryotic biomass, the LP biomass only slightly decreased with depth and eventually exceeded prokaryotic biomass in the bathypelagic layer. Sequencing identified high diversity of the LP communities with a dominance of Aplanochytrium at all depths. Notably, ASVs that were observed in the surface layer comprised ~20% of ASVs and ~60% of sequences in each of the deeper (including bathypelagic) layers, suggesting potential vertical export of the LP populations to the deep ocean. Further analyses of the vertical patterns of the 50 most abundant ASVs revealed niche partitioning of LP phylotypes in the pelagic ocean, including those that could decompose organic detritus and/or facilitate the formation of fast‐sinking particles. Overall, this study presents several lines of evidence that the LP can be an important component of the biological pump through their multiple ecotypes in the pelagic ocean.

Sterols and triterpenoids from Ganoderma lucidum and their reversal activities of tumor multidrug resistance - Min Wu; Cui-e Shen; Qiao-fa Lin; Jin-yi Zhong; Yan-fei Zhou; Ben-chen Liu; Jian-hua Xu; Zhi-qiang Zhang; Peng Li (Natural Product Research, 2022)

Biological Matrix Supply Chain Shortages: More Matrices Are Now Rare—the Case for Surrogate Matrices - Evan A. Dubiel; Heather Myler; Mark E. Arnold; Patrick Bennett; Jeff Gatz; Elizabeth Groeber; Seema Gupta; Cheikh Kane; Fumin Li; William Mylott; Courtney Noah; Mark O’Dell; et al. (The AAPS Journal, 2022)

Optimizing Method of Main Caverns in Large Underground Water-Sealed Storage Cavern - Yang An; E-Chuan Yan; Xing-Ming Li; Shao-Ping Huang (Geotechnical and Geological Engineering, 2022)

Another Record: Ocean Warming Continues through 2021 despite La Niña Conditions - Lijing Cheng; John Abraham; Kevin E. Trenberth; John Fasullo; Tim Boyer; Michael E. Mann; Jiang Zhu; Fan Wang; Ricardo Locarnini; Yuanlong Li; Bin Zhang; Zhetao Tan; et al. (Advances in Atmospheric Sciences, 2022)
The increased concentration of greenhouse gases in the atmosphere from human activities traps heat within the climate system and increases ocean heat content (OHC). Here, we provide the first analysis of recent OHC changes through 2021 from two international groups. The world ocean, in 2021, was the hottest ever recorded by humans, and the 2021 annual OHC value is even higher than last year’s record value by 14 ± 11 ZJ (1 zetta J = 10 21 J) using the IAP/CAS dataset and by 16 ± 10 ZJ using NCEI/NOAA dataset. The long-term ocean warming is larger in the Atlantic and Southern Oceans than in other regions and is mainly attributed, via climate model simulations, to an increase in anthropogenic greenhouse gas concentrations. The year-to-year variation of OHC is primarily tied to the El Niño-Southern Oscillation (ENSO). In the seven maritime domains of the Indian, Tropical Atlantic, North Atlantic, Northwest Pacific, North Pacific, Southern oceans, and the Mediterranean Sea, robust warming is observed but with distinct inter-annual to decadal variability. Four out of seven domains showed record-high heat content in 2021. The anomalous global and regional ocean warming established in this study should be incorporated into climate risk assessments, adaptation, and mitigation.

Cover Image: Volume 25 Number 3, March 2022 - Joseph A. Tobias; Catherine Sheard; Alex L. Pigot; Adam J. M. Devenish; Jingyi Yang; Ferran Sayol; Montague H. C. Neate‐Clegg; Nico Alioravainen; Thomas L. Weeks; Robert A. Barber; Patrick A. Walkden; Hannah E. A. MacGregor; et al. (Ecology Letters, 2022)

AVONET: morphological, ecological and geographical data for all birds - Joseph A. Tobias; Catherine Sheard; Alex L. Pigot; Adam J. M. Devenish; Jingyi Yang; Ferran Sayol; Montague H. C. Neate‐Clegg; Nico Alioravainen; Thomas L. Weeks; Robert A. Barber; Patrick A. Walkden; Hannah E. A. MacGregor; et al. (Ecology Letters, 2022)
Functional traits offer a rich quantitative framework for developing and testing theories in evolutionary biology, ecology and ecosystem science. However, the potential of functional traits to drive theoretical advances and refine models of global change can only be fully realised when species‐level information is complete. Here we present the AVONET dataset containing comprehensive functional trait data for all birds, including six ecological variables, 11 continuous morphological traits, and information on range size and location. Raw morphological measurements are presented from 90,020 individuals of 11,009 extant bird species sampled from 181 countries. These data are also summarised as species averages in three taxonomic formats, allowing integration with a global phylogeny, geographical range maps, IUCN Red List data and the eBird citizen science database. The AVONET dataset provides the most detailed picture of continuous trait variation for any major radiation of organisms, offering a global template for testing hypotheses and exploring the evolutionary origins, structure and functioning of biodiversity.

CropPol : A dynamic, open and global database on crop pollination - Alfonso Allen‐Perkins; Ainhoa Magrach; Matteo Dainese; Lucas A. Garibaldi; David Kleijn; Romina Rader; James R. Reilly; Rachael Winfree; Ola Lundin; Carley M. McGrady; Claire Brittain; David J. Biddinger; et al. (Ecology, 2022)
Seventy five percent of the world's food crops benefit from insect pollination. Hence, there has been increased interest in how global change drivers impact this critical ecosystem service. Because standardized data on crop pollination are rarely available, we are limited in our capacity to understand the variation in pollination benefits to crop yield, as well as to anticipate changes in this service, develop predictions, and inform management actions. Here, we present CropPol, a dynamic, open, and global database on crop pollination. It contains measurements recorded from 202 crop studies, covering 3,394 field observations, 2,552 yield measurements (i.e., berry mass, number of fruits, and fruit density [kg/ha], among others), and 47,752 insect records from 48 commercial crops distributed around the globe. CropPol comprises 32 of the 87 leading global crops and commodities that are pollinator dependent. Malus domestica is the most represented crop (32 studies), followed by Brassica napus (22 studies), Vaccinium corymbosum (13 studies), and Citrullus lanatus (12 studies). The most abundant pollinator guilds recorded are honey bees (34.22% counts), bumblebees (19.19%), flies other than Syrphidae and Bombyliidae (13.18%), other wild bees (13.13%), beetles (10.97%), Syrphidae (4.87%), and Bombyliidae (0.05%). Locations comprise 34 countries distributed among Europe (76 studies), North America (60), Latin America and the Caribbean (29), Asia (20), Oceania (10), and Africa (7). Sampling spans three decades and is concentrated on 2001–2005 (21 studies), 2006–2010 (40), 2011–2015 (88), and 2016–2020 (50). This is the most comprehensive open global data set on measurements of crop flower visitors, crop pollinators and pollination to date, and we encourage researchers to add more datasets to this database in the future. This data set is released for non‐commercial use only. Credits should be given to this paper (i.e., proper citation), and the products generated with this database should be shared under the same license terms (CC BY‐NC‐SA).

Democracy and case fatality rate of COVID-19 at early stage of pandemic: a multicountry study - Lan Yao; Minghui Li; Jim Y. Wan; Scott C. Howard; James E. Bailey; Joyce Carolyn Graff (Environmental Science and Pollution Research, 2022)

Mantle Source Components and Magmatic Evolution for the Comei Large Igneous Province: Evidence from the Early Cretaceous Niangzhong Mafic Magmatism in Tethyan Himalaya - Yaying Wang; Lingsen Zeng; Kejun Hou; Li’e Gao; Qian Wang; Linghao Zhao; Jiahao Gao; Guangxu Li (Journal of Earth Science, 2022)

Handelin extends lifespan and healthspan of Caenorhabditis elegans by reducing ROS generation and improving motor function - Huijie Zhang; Jiawei Qin; Xinqiang Lan; Weirong Zeng; Jing Zhou; Tian-E Huang; Wan-Li Xiao; Qi-Quan Wang; Sujiao Sun; Weiting Su; Wenhui Nie; Shan Yang; et al. (Biogerontology, 2022)

The genetics of vigour-related traits in chickpea (Cicer arietinum L.): insights from genomic data - Duong T. Nguyen; Julie E. Hayes; Judith Atieno; Yongle Li; Ute Baumann; Angela Pattison; Helen Bramley; Kristy Hobson; Manish Roorkiwal; Rajeev K. Varshney; Timothy D. Colmer; Tim Sutton (Theoretical and Applied Genetics, 2022)

Investigation of the risk of valproic acid–induced tremor: clinical, neuroimaging, and genetic factors - Lili Lan; Xu Zhao; Si Jian; Cun Li; Man Wang; Qing Zhou; Shanshan Huang; Suiqiang Zhu; Huicong Kang; Heidi E. Kirsch (Psychopharmacology, 2022)

Effects of environmental factors on plant functional traits across different plant life forms in a temperate forest ecosystem - Xiaoqin Cheng; Tain Ping; Zuzheng Li; Tian Wang; Hairong Han; Howard E. Epstein (New Forests, 2022)

Circular RNA screening identifies circMYLK4 as a regulator of fast/slow myofibers in porcine skeletal muscles - Haigang Cao; Jieming Liu; Tianning Du; Yihao Liu; Xiaoyu Zhang; Yuan Guo; Jie Wang; Xiaomin Zhou; Xiao Li; Gongshe Yang; Xin’e Shi (Molecular Genetics and Genomics, 2022)
The type of myofiber is related to the quality of meat. The slow oxidized myofiber helps to increase the tenderness and juiciness of muscle. Numerous studies have shown that circRNA plays a key role in skeletal muscle development. However, the role of circRNA in porcine skeletal myofiber types is unclear. In this study, we performed high-throughput RNA sequencing to study the differential expression of circRNA in the longissimus dorsi and the soleus muscle. A total of 40,757 circRNAs were identified, of which 181 were significantly different. Interestingly, some circRNAs were involved in metabolism pathways, AMPK, FoxO, and PI3K-Akt signaling pathways. Besides, we focused on a novel circRNA-circMYLK4. By injecting circMYLK4-AAV into piglets, we found that circMYLK4 significantly increased the mRNA and protein levels of the slow muscle marker genes. In summary, our study laid an essential foundation for further research of circRNA in myofiber type conversion and higher meat quality.

Genesis of the Hebaoshan gold deposit in Fujian Province of Southeast China: constraints from a combined fluid inclusion, H-O-C-S-Pb-He-Ar isotope and geochronological study - Ying Ma; Shao-Yong Jiang; Hartwig E. Frimmel; Lü-Yun Zhu; Suo-Fei Xiong; Run-Sheng Chen; Xue-Xie Li (Mineralium Deposita, 2022)

Breast intraductal nanoformulations for treating ductal carcinoma in situ II: Dose de-escalation using a slow releasing/slow bioconverting prodrug strategy - Firas Al-Zubaydi; Dayuan Gao; Dipti Kakkar; Shike Li; Jennifer Holloway; Zoltan Szekely; Nancy Chan; Shicha Kumar; Hatem E. Sabaawy; Susan Love; Patrick J. Sinko (Drug Delivery and Translational Research, 2022)

Integer ambiguity resolution and precise positioning for tight integration of BDS-3, GPS, GALILEO, and QZSS overlapping frequencies signals - Guang’e Chen; Bofeng Li; Zhiteng Zhang; Tianxia Liu (GPS Solutions, 2022)

Functional trait data for vascular plant species from northeastern North America - Donald M. Waller; Alison K. Paulson; Jeannine H. Richards; William S. Alverson; Kathryn L. Amatangelo; Chengke Bai; Sarah E. Johnson; Daijiang Li; Grégory Sonnier; Rachel H. Toczydlowski (Ecology, 2022)
Wisconsin's plant communities are responding to shifting disturbance regimes, habitat fragmentation, aerial nitrogen deposition, exotic species invasions, ungulate herbivory, and successional processes. To better understand how plant functional traits mediate species' responses to changing environmental conditions, we collected a large set of functional trait data for vascular plant species occupying Wisconsin forests and grasslands. We used standard protocols to make 76,213 measurements of 34 quantitative traits. These data provide rich information on genome size, physical leaf traits (length, width, circularity, thickness, dry matter content, specific leaf area, etc.), chemical leaf traits (carbon, nitrogen, phosphorus, potassium, calcium, magnesium, ash), life history traits (vegetative and flower heights, seed mass), and traits affecting plant palatability (leaf fiber, fat, and lignin). These trait values derive from replicate measurements on 12+ individuals of each species from multiple sites and 45+ individuals for a selected subset of species. Measurements typically reflect values for individuals although some chemical traits involved composite samples from several individuals at the same site. We also qualitatively characterized each species by plant family, woodiness, functional group, and Raunkiaer lifeform. These data allow us to characterize trait dimensionality, differentiation, and covariation among temperate plant species (e.g., leaf and stem economic syndromes). We can also characterize species' responses to environmental gradients and drivers of ecological change. With survey and resurvey data available from >400 sites in Wisconsin, we can analyze variation in community trait distributions and diversity over time and space. These data therefore allow us to assess how trait divergence vs. convergence affects community assembly and how traits may be related to half‐century shifts in the distribution and abundance of these species. The data set can be used for non‐commercial purposes. The data set is licensed as follows: CC‐By Attribution 4.0 International. We request users cite both the OSF data set and this Ecology data paper publication.

The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke - Yong-Ming Zhu; Liang Lin; Chao Wei; Yi Guo; Yuan Qin; Zhong-Sheng Li; Thomas A. Kent; Claire E. McCoy; Zhan-Xiang Wang; Yong Ni; Xian-Yong Zhou; Hui-Ling Zhang (Translational Stroke Research, 2021)
Necroptosis initiation relies on the receptor-interacting protein 1 kinase (RIP1K). We recently reported that genetic and pharmacological inhibition of RIP1K produces protection against ischemic stroke-induced astrocytic injury. However, the role of RIP1K in ischemic stroke-induced formation of astrogliosis and glial scar remains unknown. Here, in a transient middle cerebral artery occlusion (tMCAO) rat model and an oxygen and glucose deprivation and reoxygenation (OGD/Re)-induced astrocytic injury model, we show that RIP1K was significantly elevated in the reactive astrocytes. Knockdown of RIP1K or delayed administration of RIP1K inhibitor Nec-1 down-regulated the glial scar markers, improved ischemic stroke-induced necrotic morphology and neurologic deficits, and reduced the volume of brain atrophy. Moreover, knockdown of RIP1K attenuated astrocytic cell death and proliferation and promoted neuronal axonal generation in a neuron and astrocyte co-culture system. Both vascular endothelial growth factor D (VEGF-D) and its receptor VEGFR-3 were elevated in the reactive astrocytes; simultaneously, VEGF-D was increased in the medium of astrocytes exposed to OGD/Re. Knockdown of RIP1K down-regulated VEGF-D gene and protein levels in the reactive astrocytes. Treatment with 400 ng/ml recombinant VEGF-D induced the formation of glial scar; conversely, the inhibitor of VEGFR-3 suppressed OGD/Re-induced glial scar formation. RIP3K and MLKL may be involved in glial scar formation. Taken together, these results suggest that RIP1K participates in the formation of astrogliosis and glial scar via impairment of normal astrocyte responses and enhancing the astrocytic VEGF-D/VEGFR-3 signaling pathways. Inhibition of RIP1K promotes the brain functional recovery partially via suppressing the formation of astrogliosis and glial scar. Graphical Abstract

Biallelic variants in YRDC cause a developmental disorder with progeroid features - Julia Schmidt; Jonas Goergens; Tatiana Pochechueva; Annika Kotter; Niko Schwenzer; Maren Sitte; Gesa Werner; Janine Altmüller; Holger Thiele; Peter Nürnberg; Jörg Isensee; Yun Li; et al. (Human Genetics, 2021)
The highly conserved YrdC domain-containing protein (YRDC) interacts with the well-described KEOPS complex, regulating specific tRNA modifications to ensure accurate protein synthesis. Previous studies have linked the KEOPS complex to a role in promoting telomere maintenance and controlling genome integrity. Here, we report on a newborn with a severe neonatal progeroid phenotype including generalized loss of subcutaneous fat, microcephaly, growth retardation, wrinkled skin, renal failure, and premature death at the age of 12 days. By trio whole-exome sequencing, we identified a novel homozygous missense mutation, c.662T > C, in YRDC affecting an evolutionary highly conserved amino acid (p.Ile221Thr). Functional characterization of patient-derived dermal fibroblasts revealed that this mutation impairs YRDC function and consequently results in reduced t 6 A modifications of tRNAs. Furthermore, we established and performed a novel and highly sensitive 3-D Q-FISH analysis based on single-telomere detection to investigate the impact of YRDC on telomere maintenance. This analysis revealed significant telomere shortening in YRDC-mutant cells. Moreover, single-cell RNA sequencing analysis of YRDC-mutant fibroblasts revealed significant transcriptome-wide changes in gene expression, specifically enriched for genes associated with processes involved in DNA repair. We next examined the DNA damage response of patient’s dermal fibroblasts and detected an increased susceptibility to genotoxic agents and a global DNA double-strand break repair defect. Thus, our data suggest that YRDC may affect the maintenance of genomic stability. Together, our findings indicate that biallelic variants in YRDC result in a developmental disorder with progeroid features and might be linked to increased genomic instability and telomere shortening.

Chlorogenic acid inhibits apoptosis in thiram-induced tibial dyschondroplasia via intrinsic pathway - Jialu Zhang; Bihao Luo; Juanjuan Liu; Muhammad Waqas; Muhammad Fakhar-e-Alam Kulyar; Kangkang Guo; Jiakui Li (Environmental Science and Pollution Research, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

Effects of Varied Stimulation Parameters on Adipose-Derived Stem Cell Response to Low-Level Electrical Fields - Nora Hlavac; Deanna Bousalis; Raffae N. Ahmad; Emily Pallack; Angelique Vela; Yuan Li; Sahba Mobini; Erin Patrick; Christine E. Schmidt (Annals of Biomedical Engineering, 2021)

Investigation of the Compressive Viscoelastic Properties of Brain Tissue Under Time and Frequency Dependent Loading Conditions - Weiqi Li; Duncan E. T. Shepherd; Daniel M. Espino (Annals of Biomedical Engineering, 2021)
The mechanical characterization of brain tissue has been generally analyzed in the frequency and time domain. It is crucial to understand the mechanics of the brain under realistic, dynamic conditions and convert it to enable mathematical modelling in a time domain. In this study, the compressive viscoelastic properties of brain tissue were investigated under time and frequency domains with the same physical conditions and the theory of viscoelasticity was applied to estimate the prediction of viscoelastic response in the time domain based on frequency-dependent mechanical moduli through Finite Element models. Storage and loss modulus were obtained from white and grey matter, of bovine brains, using dynamic mechanical analysis and time domain material functions were derived based on a Prony series representation. The material models were evaluated using brain testing data from stress relaxation and hysteresis in the time dependent analysis. The Finite Element models were able to represent the trend of viscoelastic characterization of brain tissue under both testing domains. The outcomes of this study contribute to a better understanding of brain tissue mechanical behaviour and demonstrate the feasibility of deriving time-domain viscoelastic parameters from frequency-dependent compressive data for biological tissue, as validated by comparing experimental tests with computational simulations.

Seasonal Rainfall Forecasts for the Yangtze River Basin in the Extreme Summer of 2020 - Philip E. Bett; Gill M. Martin; Nick Dunstone; Adam A. Scaife; Hazel E. Thornton; Chaofan Li (Advances in Atmospheric Sciences, 2021)

The Seasonal Prediction of the Exceptional Yangtze River Rainfall in Summer 2020 - Chaofan Li; Riyu Lu; Nick Dunstone; Adam A. Scaife; Philip E. Bett; Fei Zheng (Advances in Atmospheric Sciences, 2021)

Mapping flood extend and its impact on land use/land cover and settlements variations: a case study of Layyah District, Punjab, Pakistan - Shan-e-hyder Soomro; Caihong Hu; Muhammad Waseem Boota; Mairaj Hyder Alias Aamir Soomro; Shengqi Jian; Zeeshan Zafar; Xiaoping Li (Acta Geophysica, 2021)

Correction to: Considerations for Updates to ICH Q1 and Q5C Stability Guidelines: Embracing Current Technology and Risk Assessment Strategies - Megan E. McMahon; Alexander Abbott; Yelizaveta Babayan; Jenny Carhart; Chi-wan Chen; Elke Debie; Mingkun Fu; Cherokee Hoaglund-Hyzer; Andrew Lennard; Hanlin Li; Tony Mazzeo; Lori McCaig; et al. (The AAPS Journal, 2021)

Considerations for Updates to ICH Q1 and Q5C Stability Guidelines: Embracing Current Technology and Risk Assessment Strategies - Megan E. McMahon; Alexander Abbott; Yelizaveta Babayan; Jenny Carhart; Chi-wan Chen; Elke Debie; Mingkun Fu; Cherokee Hoaglund-Hyzer; Andrew Lennard; Hanlin Li; Tony Mazzeo; Lori McCaig; et al. (The AAPS Journal, 2021)

Systemic Elevation of n-3 Polyunsaturated Fatty Acids (n-3-PUFA) Is Associated with Protection against Visual, Motor, and Emotional Deficits in Mice following Closed-Head Mild Traumatic Brain Injury - Koushik Mondal; Haruka Takahashi; Jerome Cole; Nobel A. Del Mar; Chunyan Li; Daniel J. Stephenson; Jeremy Allegood; L. Ashley Cowart; Charles E. Chalfant; Anton Reiner; Nawajes Mandal (Molecular Neurobiology, 2021)

A 168-year temperature recording based on tree rings and latitude differences in temperature changes in northeast China - Yangao Jiang; Yuting Cao; Junhui Zhang; Zhuo Li; Guoqiang Shi; Shijie Han; Cassius E. O. Coombs; Chuan Liu; Xiaoguang Wang; Junwei Wang; Lin Hao; Qi Xu; et al. (International Journal of Biometeorology, 2021)

Emergy-based ecological efficiency evaluation and optimization method for logistics park - Cui Wang; Cuixia Zhang; Fagang Hu; Yuan Wang; Li’e Yu; Conghu Liu (Environmental Science and Pollution Research, 2021)

Bacterial Viruses Subcommittee and Archaeal Viruses Subcommittee of the ICTV: update of taxonomy changes in 2021 - Mart Krupovic; Dann Turner; Vera Morozova; Mike Dyall-Smith; Hanna M. Oksanen; Rob Edwards; Bas E. Dutilh; Susan M. Lehman; Alejandro Reyes; Diana P. Baquero; Matthew B. Sullivan; Jumpei Uchiyama; et al. (Archives of Virology, 2021)
In this article, we – the Bacterial Viruses Subcommittee and the Archaeal Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV) – summarise the results of our activities for the period March 2020 – March 2021. We report the division of the former Bacterial and Archaeal Viruses Subcommittee in two separate Subcommittees, welcome new members, a new Subcommittee Chair and Vice Chair, and give an overview of the new taxa that were proposed in 2020, approved by the Executive Committee and ratified by vote in 2021. In particular, a new realm, three orders, 15 families, 31 subfamilies, 734 genera and 1845 species were newly created or redefined (moved/promoted).

Nitrogen addition amplifies the nonlinear drought response of grassland productivity to extended growing‐season droughts - Bo Meng; Junqin Li; Gregory E. Maurer; Shangzhi Zhong; Yuan Yao; Xuechen Yang; Scott L. Collins; Wei Sun (Ecology, 2021)
Understanding the response of grassland production and carbon exchange to intra‐annual variation in precipitation and nitrogen addition is critical for sustainable grassland management and ecosystem restoration. We introduced growing‐season drought treatments of different lengths (15, 30, 45 and 60 d drought) by delaying growing‐season precipitation in a long‐term nitrogen addition experiment in a low diversity meadow steppe in northeast China. Response variables included aboveground biomass (AGB), ecosystem net carbon exchange (NEE), and leaf net carbon assimilation rate ( A ). In unfertilized plots drought decreased AGB by 13.7% after a 45‐d drought and 31.7% after a 60‐d drought (47.6% in fertilized plots). Progressive increases in the drought response of NEE were also observed. The effects of N addition on the drought response of productivity increased as drought duration increased, and these responses were a function of changes in AGB and biomass allocation, particularly root to shoot ratio. However, no significant effects of drought occurred in fertilized or unfertilized plots in the growing season a year after the experiment, N addition did limit the recovery of AGB from severe drought during the remainder of the current growing season. Our results imply that chronic N enrichment could exacerbate the effects of growing‐season drought on grassland productivity caused by altered precipitation seasonality under climate change, but that these effects do not carry over to the next growing season.

W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34 - Raghavendra Y. Nagaraja; David M. Sherry; Jennifer L. Fessler; Megan A. Stiles; Feng Li; Karanpreet Multani; Albert Orock; Mohiuddin Ahmad; Richard S. Brush; Robert E. Anderson; Martin-Paul Agbaga; Ferenc Deák (Molecular Neurobiology, 2021)
Spinocerebellar ataxia (SCA) is a neurodegenerative disorder characterized by ataxia and cerebellar atrophy. A number of different mutations gives rise to different types of SCA with characteristic ages of onset, symptomatology, and rates of progression. SCA type 34 (SCA34) is caused by mutations in ELOVL4 (ELOngation of Very Long-chain fatty acids 4), a fatty acid elongase essential for biosynthesis of Very Long Chain Saturated and Polyunsaturated Fatty Acids (VLC-SFA and VLC-PUFA, resp., ≥28 carbons), which have important functions in the brain, skin, retina, Meibomian glands, testes, and sperm. We generated a rat model of SCA34 by knock-in of the SCA34-causing 736T>G (p.W246G) ELOVL4 mutation. Rats carrying the mutation developed impaired motor deficits by 2 months of age. To understand the mechanism of these motor deficits, we performed electrophysiological studies using cerebellar slices from rats homozygous for W246G mutant ELOVL4 and found marked reduction of long-term potentiation at parallel fiber synapses and long-term depression at climbing fiber synapses onto Purkinje cells. Neuroanatomical analysis of the cerebellum showed normal cytoarchitectural organization with no evidence of degeneration out to 6 months of age. These results point to ELOVL4 as essential for motor function and cerebellar synaptic plasticity. The results further suggest that ataxia in SCA34 patients may arise from a primary impairment of synaptic plasticity and cerebellar network desynchronization before onset of neurodegeneration and progression of the disease at a later age.

Spartina alterniflora saltmarsh soil organic carbon properties and sources in coastal wetlands - Jin-e Liu; Dailan Deng; Caiyu Zou; Ruiming Han; Yue Xin; Zihao Shu; Li-min Zhang (Journal of Soils and Sediments, 2021)

The Toxicology Investigators Consortium 2020 Annual Report - Meghan B. Spyres; Kim Aldy; Lynn A Farrugia; A. Min Kang; Jennifer S. Love; Sharan L. Campleman; Shao Li; Alexandra Amaducci; Evan Schwarz; Paul M. Wax; Jeffery Brent; J. Acciani; et al. (Journal of Medical Toxicology, 2021)

Pterocarpus marsupium extract extends replicative lifespan in budding yeast - Mitchell B. Lee; Michael G. Kiflezghi; Mitsuhiro Tsuchiya; Brian Wasko; Daniel T. Carr; Priya A. Uppal; Katherine A. Grayden; Yordanos C. Elala; Tu Anh Nguyen; Jesse Wang; Priya Ragosti; Sunny Nguyen; et al. (GeroScience, 2021)

Relaxation of Selective Constraint on the Ultra-Large Mitochondrial Genomes of Arcidae (Mollusca: Bivalvia) - Shao’e Sun; Qi Li; Lingfeng Kong (Journal of Ocean University of China, 2021)

The glycosyltransferase ST3GAL2 modulates virus proliferation and the inflammation response in porcine reproductive and respiratory syndrome virus infection - Xiaoyang Li; Yanyu Guo; Yinna Song; Ruiqi Sun; Min Zhu; Zheng Tan; Umm E Swaiba; Lilin Zhang; Jinhai Huang (Archives of Virology, 2021)

Capabilities and limitations of using DNA metabarcoding to study plant–pollinator interactions - Katherine A. Arstingstall; Sandra J. DeBano; Xiaoping Li; David E. Wooster; Mary M. Rowland; Skyler Burrows; Kenneth Frost (Molecular Ecology, 2021)
Many pollinator populations are experiencing declines, emphasizing the need for a better understanding of the complex relationship between bees and flowering plants. Using DNA metabarcoding to describe plant–pollinator interactions eliminates many challenges associated with traditional methods and has the potential to reveal a more comprehensive understanding of foraging behaviour and pollinator life history. Here we use DNA metabarcoding of ITS2 and rbcL gene regions to identify plant species present in pollen loads of 404 bees from three habitats in eastern Oregon. Our specific objectives were to (i) determine whether plant species identified using DNA metabarcoding are consistent with plant species identified using observations, (ii) compare characterizations of diet breadth derived from foraging observations to those based on plant species assignments obtained using DNA metabarcoding, and (iii) compare plant species assignments produced by DNA metabarcoding using a “regional” reference database to those produced using a “local” database. At the three locations, 31%–86% of foraging observations were consistent with DNA metabarcoding data, 8%–50% of diet breadth characterizations based on observations differed from those based on DNA metabarcoding data, and 22%–25% of plant species detected using the regional database were not known to occur in the study area in question. Plant–pollinator networks produced from DNA metabarcoding data had higher sampling completeness and significantly lower specialization than networks based on observations. Here, we examine some strengths and limitations of using DNA metabarcoding to identify plant species present in bee pollen loads, make ecological inferences about foraging behaviour and provide guidance for future research.

Shifting roles of the East China Sea in the phylogeography of red nanmu in East Asia - Kai Jiang; Xin Tong; Yan‐Qian Ding; Zheng‐Wei Wang; Li‐Yuan Miao; Yue‐E Xiao; Wei‐Chang Huang; Yong‐Hong Hu; Xiao‐Yong Chen (Journal of Biogeography, 2021)
Aim The effect of eustasy driven by climatic oscillations on species diversification across the East China Sea (ECS) remains unclear. In this study, Machilus thunbergii (红楠, red nanmu in Chinese) was used as a model species to determine whether the ECS acted as either a “species pump” or “species vacuum” during the Pleistocene. Locations Eastern China, and southern and central Japan. Taxon Lauraceae. Methods Ecological niche modelling was employed to predict the potential distribution of M . thunbergii during the Last Glacial Maximum (LGM) and the last interglacial period. Nuclear microsatellite and chloroplast markers were used to reveal the phylogeographic pattern and infer the population history of 33 M . thunbergii populations. Results The ecological niche models suggested that the ECS provided potentially suitable habitats for M. thunbergii during the LGM. A sharp change in cpDNA haplotypes was found along the eastern China coasts, while microsatellites revealed a clinal pattern for genetic composition from eastern China to central Japan. The divergent lineages formed an admixture on the Zhoushan Archipelago of China and Kyushu Island of Japan. The estimated divergent and admixture times were c . 68 kyr and c . 15 kyr, corresponding to the periods where there were rising sea levels after the MIS4 glaciation and falling sea levels during the LGM, respectively. Main conclusions Machilus thunbergii probably underwent alternating population isolation during interglacial periods and connection during glacial maxima across the ECS, but such periodicity of isolation and connection seems not to have promoted diversification as suggested by the species pump hypothesis. Incipient divergence has been periodically wiped out due to frequent coalescence, rendering the ECS more like a “species vacuum”, particularly for species with relatively long generation lengths.

Seasonal changes in GPP/SIF ratios and their climatic determinants across the Northern Hemisphere - Anping Chen; Jiafu Mao; Daniel Ricciuto; Dan Lu; Jingfeng Xiao; Xing Li; Peter E. Thornton; Alan K. Knapp (Global Change Biology, 2021)
Satellite‐derived sun‐induced chlorophyll fluorescence (SIF) has been increasingly used for estimating gross primary production (GPP). However, the relationship between SIF and GPP has not been well defined, impeding the translation of satellite observed SIF to GPP. Previous studies have generally assumed a linear relationship between SIF and GPP at daily and longer time scales, but support for this assumption is lacking. Here, we used the GPP/SIF ratio to investigate seasonal variations in the relationship between SIF and GPP over the Northern Hemisphere (NH). Based on multiple SIF products and MODIS and FLUXCOM GPP data, we found strong seasonal hump‐shaped patterns for the GPP/SIF ratio over northern latitudes, with higher values in the summer than in the spring or autumn. This hump‐shaped GPP/SIF seasonal variation was confirmed by examining different SIF products and was evident for most vegetation types except evergreen broadleaf forests. The seasonal amplitude of the GPP/SIF ratio decreased from the boreal/arctic region to drylands and the tropics. For most of the NH, the lowest GPP/SIF values occurred in October or September, while the maximum GPP/SIF values were evident in June and July. The most pronounced seasonal amplitude of GPP/SIF occurred in intermediate temperature and precipitation ranges. GPP/SIF was positively related to temperature in the early and late parts of the growing season, but not during the peak growing months. These shifting relationships between temperature and GPP/SIF across different months appeared to play a key role in the seasonal dynamics of GPP/SIF. Several mechanisms may explain the patterns we observed, and future research encompassing a broad range of climate and vegetation settings is needed to improve our understanding of the spatial and temporal relationships between SIF and GPP. Nonetheless, the strong seasonal variation in GPP/SIF we identified highlights the importance of incorporating this behavior into SIF‐based GPP estimations.

Rice domestication influences the composition and function of the rhizosphere bacterial chemotaxis systems - Yu Sun; Lei Tian; Jingjing Chang; Shaohua Shi; Jianfeng Zhang; Hongwei Xie; Yaohui Cai; Dazhou Chen; Eiko E. Kuramae; Johannes A. van Veen; Weiqiang Li; Lam-Son Phan Tran; et al. (Plant and Soil, 2021)