Recyclable nanocomposites for carbon dioxide fixation and membrane separation using waste polycarbonate - Ying-Chi Huang; Li-Fan Chen; Yu-Hsiang Huang; Chien-Chieh Hu; Chien-Hsin Wu; Ru-Jong Jeng (Chemical Engineering Journal, 2023)

Design of bipolar polymer electrodes for symmetric Li-dual-ion batteries - Bangshuai Wei; Yan Hong; Wu Tang; Meichen Guo; Xuesong He; Chenbin Tang; Jiahui Hu; Cong Fan (Chemical Engineering Journal, 2023)

Chitosan based photothermal scaffold fighting against bone tumor-related complications: Recurrence, infection, and defects - Yao Zhao; Xu Peng; Xiaoyang Xu; Mingzhen Wu; Fan Sun; Qiangwei Xin; Hongbo Zhang; Liangrui Zuo; Yilin Cao; Yuhang Xia; Jun Luo; Chunmei Ding; et al. (Carbohydrate Polymers, 2023)

Recent progress of electrolytes and electrocatalysts in neutral aqueous zinc-air batteries - Wei-Fan Wu; Xingbin Yan; Yi Zhan (Chemical Engineering Journal, 2023)

Corrigendum to “Bio-synthesis of co-doped FeMnOx and its efficient activation of peroxymonosulfate for the degradation of moxifloxacin” [Chem. Eng. J. 435 (2022) 134695] - Anlin Xu; Donghong Wu; Ren Zhang; Siyan Fan; Albert T. Lebedev; Yongjun Zhang (Chemical Engineering Journal, 2023)

Synergistically enhanced heat conductivity-microwave absorption capabilities of g-C3N4@Fe@C hollow micro-polyhedra via interface and composition modulation - Baoxin Fan; Lu Xing; Kaixia Yang; Fanjie Zhou; Qianmei He; Guoxiu Tong; Wenhua Wu (Chemical Engineering Journal, 2023)

Polar Co9S8 anchored on Pyrrole-Modified graphene with in situ growth of CNTs as multifunctional Self-Supporting medium for efficient Lithium-Sulfur batteries - Lin Sun; Yanxiu Liu; Jie Xie; Lele Fan; Jun Wu; Ruiyu Jiang; Zhong Jin (Chemical Engineering Journal, 2023)

The pre-addition of “blocking” proteins decreases subsequent cellulase adsorption to lignin and enhances cellulose hydrolysis - Jingyun Liu; Jie Wu; Yi Lu; Huaiyu Zhang; Qi Hua; Ran Bi; Orlando Rojas; Scott Renneckar; Senqing Fan; Zeyi Xiao; Jack Saddler (Bioresource Technology, 2023)

Source apportionment of VOCs based on photochemical loss in summer at a suburban site in Beijing - Yajun Wu; Xiaolong Fan; Yan Liu; Jingqiao Zhang; Han Wang; Luna Sun; Tiange Fang; Hongjun Mao; Jun Hu; Lin Wu; Jianfei Peng; Shulan Wang (Atmospheric Environment, 2023)

Groundwater Quality Evaluation and Analysis Technology Based on AHP-EWM-GRA and Its Application - Menghua Li; Bo Li; Jingyan Chu; Huang Wu; Zhicheng Yang; Juan Fan; Lei Yang; Pu Liu; Jie Long (Water, Air, & Soil Pollution, 2023)

Single-cell transcriptomics of immune cells in lymph nodes reveals their composition and alterations in functional dynamics during the early stages of bubonic plague - Yifan Zhao; Tong Wang; Ziyang Liu; Yuehua Ke; Ruoyan Li; Hongyan Chen; Yang You; Gengshan Wu; Shiyang Cao; Zongmin Du; Fan Bai; Ruifu Yang (Science China Life Sciences, 2023)

Conserved and divergent evolution of the bZIP transcription factor in five diploid Gossypium species - Fangting Ye; Xiaogang Zhu; Shaofang Wu; Yunyue Du; Xinfeng Pan; Yuchen Wu; Zhengyi Qian; Zhaowei Li; Wenxiong Lin; Kai Fan (Planta, 2023)

Interaction mechanism between nitrogen conversion and the microbial community in the hydrodynamic heterogeneous interaction zone - Lei Duan; Jinghui Fan; Yike Wang; Yakun Wu; Chenchen Xie; Fei Ye; Jiajia Lv; Ming Mao; Yaqiao Sun (Environmental Science and Pollution Research, 2023)

Long-Term Phosphorus Addition Strongly Weakens the Carbon Sink Function of a Temperate Peatland - Fan Lu; Jianghua Wu; Boli Yi; Zhiwei Xu; Meng Wang; Sebastian Sundberg; Zhao-Jun Bu (Ecosystems, 2023)

Effect of herbaceous plants on the response of loose silty sand slope under rainfall - Pei Tai; Fan Wu; Rui Chen; Jingqi Zhu; Xiong Wang; Min Zhang (Bulletin of Engineering Geology and the Environment, 2023)

How can diverse national food and land-use priorities be reconciled with global sustainability targets? Lessons from the FABLE initiative - Aline Mosnier; Guido Schmidt-Traub; Michael Obersteiner; Sarah Jones; Valeria Javalera-Rincon; Fabrice DeClerck; Marcus Thomson; Frank Sperling; Paula Harrison; Katya Pérez-Guzmán; Gordon Carlos McCord; Javier Navarro-Garcia; et al. (Sustainability Science, 2023)
There is an urgent need for countries to transition their national food and land-use systems toward food and nutritional security, climate stability, and environmental integrity. How can countries satisfy their demands while jointly delivering the required transformative change to achieve global sustainability targets? Here, we present a collaborative approach developed with the FABLE—Food, Agriculture, Biodiversity, Land, and Energy—Consortium to reconcile both global and national elements for developing national food and land-use system pathways. This approach includes three key features: (1) global targets, (2) country-driven multi-objective pathways, and (3) multiple iterations of pathway refinement informed by both national and international impacts. This approach strengthens policy coherence and highlights where greater national and international ambition is needed to achieve global goals (e.g., the SDGs). We discuss how this could be used to support future climate and biodiversity negotiations and what further developments would be needed.

Rapid discrimination of enantiomers by ion mobility mass spectrometry and chemical theoretical calculation: Chiral mandelic acid and its derivatives - Huanhuan Wang; Fangling Wu; Xinhua Dai; Xiang Fang; Chuan-Fan Ding (Analytica Chimica Acta, 2023)

Data-driven prescribed performance control for satellite with large rotational component - Ziran Liu; Chengfei Yue; Fan Wu; Feng Wang; Xibin Cao (Advances in Space Research, 2023)

What adverse health effects will environmental heavy metal co-exposure bring us: based on a biological monitoring study of sanitation workers - Zhilin Li; Hongxuan Kuang; Leizi Li; Maorong Wu; Zengquan Liao; Keqin Zeng; Yufeng Ye; Ruifang Fan (Environmental Science and Pollution Research, 2022)

Water consumption prediction and influencing factor analysis based on PCA-BP neural network in karst regions: a case study of Guizhou Province - Zhicheng Yang; Bo Li; Huang Wu; MengHua Li; Juan Fan; Mengyu Chen; Jie Long (Environmental Science and Pollution Research, 2022)

Nucleosides and amino acids, isolated from Cordyceps sinensis, protected against cyclophosphamide-induced myelosuppression in mice - Yu Zhang; Jie Liu; Yan Wang; Chengpeng Sun; Wenjia Li; Jianjian Qiu; Yanling Qiao; Fan Wu; Xiaokui Huo; Yue An; Baojing Zhang; Shuangcheng Ma; et al. (Natural Product Research, 2022)

Radial growth response of Quercus liaotungensis to climate change–a case study on the central Loess Plateau, China - Maierdang Keyimu; Zongshan Li; Lei Jiao; Weiliang Chen; Xiuchen Wu; Zexin Fan; Fanjiang Zeng; Bojie Fu (Trees, 2022)

QNE1 is a key flowering regulator determining the length of the vegetative period in soybean cultivars - Zhengjun Xia; Hong Zhai; Yanfeng Zhang; Yaying Wang; Lu Wang; Kun Xu; Hongyan Wu; Jinglong Zhu; Shuang Jiao; Zhao Wan; Xiaobin Zhu; Yi Gao; et al. (Science China Life Sciences, 2022)

Correction to: Brucine-Induced Neurotoxicity by Targeting Caspase 3: Involvement of PPARγ/NF-κB/Apoptosis Signaling Pathway - Yaying Lei; Fangqin Hou; Xiaoyu Wu; Yang Yi; Fan Xu; Qihai Gong; Jianmei Gao (Neurotoxicity Research, 2022)

Brucine-Induced Neurotoxicity by Targeting Caspase 3: Involvement of PPARγ/NF-κB/Apoptosis Signaling Pathway - Yaying Lei; Fangqin Hou; Xiaoyu Wu; Yang Yi; Fan Xu; Qihai Gong; Jianmei Gao (Neurotoxicity Research, 2022)

Viral Tools for Neural Circuit Tracing - Qing Liu; Yang Wu; Huadong Wang; Fan Jia; Fuqiang Xu (Neuroscience Bulletin, 2022)

Correction: Topotecan Reduces Neuron Death after Spinal Cord Injury by Suppressing Caspase-1-Dependent Pyroptosis - Wu Jiang; Fan He; Guoming Ding; Junsong Wu (Molecular Neurobiology, 2022)

Temporal Dynamics of Antibiotic Resistance Genes in Vegetable Greenhouse Soils Following Different Manure Applications - Xuexia Yuan; Yong Zhang; Lixia Fan; Wenbo Wang; Yuanjuan Wu (Journal of Soil Science and Plant Nutrition, 2022)

Renoprotective effects of empagliflozin in type 1 and type 2 models of diabetic nephropathy superimposed with hypertension - Jan M. Williams; Sydney R. Murphy; Wenjie Wu; Jane J. Border; Fan Fan; Richard J. Roman (GeroScience, 2022)

Co-axial Projective Imaging for Augmented Reality Telementoring in Skin Cancer Surgery - Fan Zhang; Carlo M. Contreras; Pengfei Shao; Liping Zhao; Bingxuan Wu; Chenmeng Li; Feng Lin; Xiaohong Zhong; Zhongliang Lang; Peng Liu; Ronald X. Xu (Annals of Biomedical Engineering, 2022)

Identification of nitrogen pollution sources and transport transformation processes in groundwater of different landforms using C, H, N, and O isotope techniques: an example from the lower Weihe River - Lei Duan; Yakun Wu; Jinghui Fan; Fei Ye; Chenchen Xie; Xinyi Fu; Yaqiao Sun (Environmental Science and Pollution Research, 2022)

Production of Hydroxyl Radicals from Oxygenation of Simulated Acid Mine Drainage in Presence of Extracellular Polymers Substances - Xuewen Zhong; Fang Liu; Pan Wu; Feifei Fan; Jian Zhu (Bulletin of Environmental Contamination and Toxicology, 2022)

Rapid emergence of a PB2 D701N substitution during adaptation of an H9N2 avian influenza virus in mice - Fan Yang; Xiaodi Zhang; Fumin Liu; Hangping Yao; Nanping Wu; Haibo Wu (Archives of Virology, 2022)

The effects of human care on the blowhole and gut microbiotas of two cohabiting dolphin species based on a year-round surveillance - Xiaoling Wan; Jia Li; Renmao Tian; Richard William McLaughlin; Yujiang Hao; Junyi Wu; Zhengyang Wang; Fei Fan; Ding Wang; Jinsong Zheng (Frontiers in Marine Science, 2022)
Understanding the effects of human care on the dynamics of the host-associated microbiota is critical for the health management of dolphins living in an aquarium. Yet this aspect remains relatively unexplored. Here, by utilizing 16S rRNA gene sequencing, we profiled the blowhole and gut bacterial communities of two bottlenose dolphins ( Tursiops truncatus ) and a Chinese white dolphin ( Sousa chinensis ) reared in the same indoor pool, based on year-round surveillance. In addition, we compared these dolphin microbiotas with those previously published datasets from wild dolphins. Our results showed that both the blowhole and the gut of the two dolphin species under human care shared a more similar microbiome than members of the same dolphin species across different habitats (human care vs wild). However, the effects of human care on the dolphin microbiome from the two body sites varied. In the aquarium, bacterial alpha diversities differed significantly between the two body sites, and the seasonal stability of the bacterial community was more evident in the gut than in the blowhole. Additionally, the blowhole bacterial composition and the predicted functional capacity from the two dolphin species showed differences and were less convergent than their gut microbiota over a decade-long cohabitation. Further analyses showed that heterogeneous and homogeneous selections (i.e., deterministic processes) contributed more to the blowhole than to the gut bacterial communities, while a dispersal limitation (i.e., a stochastic process) was more important for the gut microbiota. The present study provides the first comparative evidence that the gut microbiota may be more plastic in response to the human care environment than the blowhole microbiota. This improves our understanding of dolphin health management under human care and helps to predict their microbial responses to environmental changes.

Visualization and quantification of carbon “rusty sink” by rice root iron plaque: Mechanisms, functions, and global implications - Liang Wei; Zhenke Zhu; Bahar S. Razavi; Mouliang Xiao; Maxim Dorodnikov; Lichao Fan; Hongzhao Yuan; Andrey Yurtaev; Yu Luo; Weiguo Cheng; Yakov Kuzyakov; Jinshui Wu; et al. (Global Change Biology, 2022)
Paddies contain 78% higher organic carbon (C) stocks than adjacent upland soils, and iron (Fe) plaque formation on rice roots is one of the mechanisms that traps C. The process sequence, extent and global relevance of this C stabilization mechanism under oxic/anoxic conditions remains unclear. We quantified and localized the contribution of Fe plaque to organic matter stabilization in a microoxic area (rice rhizosphere) and evaluated roles of this C trap for global C sequestration in paddy soils. Visualization and localization of pH by imaging with planar optodes, enzyme activities by zymography, and root exudation by 14 C imaging, as well as upscale modeling enabled linkage of three groups of rhizosphere processes that are responsible for C stabilization from the micro‐ (root) to the macro‐ (ecosystem) levels. The 14 C activity in soil (reflecting stabilization of rhizodeposits) with Fe 2+ addition was 1.4–1.5 times higher than that in the control and phosphate addition soils. Perfect co‐localization of the hotspots of β‐glucosidase activity (by zymography) with root exudation ( 14 C) showed that labile C and high enzyme activities were localized within Fe plaques. Fe 2+ addition to soil and its microbial oxidation to Fe 3+ by radial oxygen release from rice roots increased Fe plaque (Fe 3+ ) formation by 1.7–2.5 times. The C amounts trapped by Fe plaque increased by 1.1 times after Fe 2+ addition. Therefore, Fe plaque formed from amorphous and complex Fe (oxyhydr)oxides on the root surface act as a “rusty sink” for organic matter. Considering the area of coverage of paddy soils globally, upscaling by model revealed the radial oxygen loss from roots and bacterial Fe oxidation may trap up to 130 Mg C in Fe plaques per rice season. This represents an important annual surplus of new and stable C to the existing C pool under long‐term rice cropping.

The impact of cross-shareholding under different power structures considering green investment and green marketing - Hao Liu; Sheng Wu; Xinyue Zhao; Haodong Chen; Guobao Wang; Zhigang Song; Yuqing Fan (Environmental Science and Pollution Research, 2022)

Stochastic simulation of seawater intrusion in the Longkou area of China based on the Monte Carlo method - Yue Fan; Qinghua Wu; Haodong Cui; Wenxi Lu; Wanli Ren (Environmental Science and Pollution Research, 2022)

Short-term effect of ambient temperature and ambient temperature changes on the risk of warts outpatient visits in Hefei, China: a retrospective time-series study - Bo Liu; Xin-Yu Fang; Yu-Lu Yan; Jun Wu; Xiao-Jie Lv; Jie Zhang; Liang-Wei Qi; Ting-Ting Qian; Yu-Yu Cai; Yin-Guang Fan; Dong-Qing Ye (Environmental Science and Pollution Research, 2022)

Co-pyrolysis of biomass and phosphate tailing to produce potential phosphorus-rich biochar: efficient removal of heavy metals and the underlying mechanisms - Fan Yang; Junfan Lv; Yingying Zhou; Shuang Wu; Jingke Sima (Environmental Science and Pollution Research, 2022)

Fine mapping of the reduced height gene Rht22 in tetraploid wheat landrace Jianyangailanmai (Triticum turgidum L.) - Chao Wang; Yunjing Bao; Qin Yao; Dan Long; Xue Xiao; Xing Fan; Houyang Kang; Jian Zeng; Lina Sha; Haiqin Zhang; Dandan Wu; Yonghong Zhou; et al. (Theoretical and Applied Genetics, 2022)

Ketamine induces rapid antidepressant effects via the autophagy-NLRP3 inflammasome pathway - Dongbin Lyu; Fan Wang; Mengke Zhang; Weichieh Yang; Haijing Huang; Qinte Huang; Chenglin Wu; Nuoshi Qian; Meiti Wang; Huanfei Zhang; Sichai Zheng; Jing Chen; et al. (Psychopharmacology, 2022)

Topotecan Reduces Neuron Death after Spinal Cord Injury by Suppressing Caspase-1-Dependent Pyroptosis - Wu Jiang; Fan He; Guoming Ding; Junsong Wu (Molecular Neurobiology, 2022)

Effects of the aeration mode on nitrogen removal in a compact constructed rapid infiltration system for advanced wastewater treatment - Xiejuan Lu; Minggang Gao; Si Yang; Dingding Tang; Fan Yang; Yangfan Deng; Yan Zhou; Xiaohui Wu; Feixiang Zan (Environmental Science and Pollution Research, 2022)

Detecting and monitoring tumors in orthotopic colorectal liver metastatic animal models with high-resolution ultrasound - Shengcai Wei; Yiqun Liu; Yuwei Xin; Caizhen Feng; Yinli Zhang; Xiaoxuan Jia; Fan Chai; Jiaqi Zhao; Yulu Liu; Xun Yao; Xiaoyi Liu; Jing Wu; et al. (Clinical & Experimental Metastasis, 2022)

Increased virulence of a novel reassortant H1N3 avian influenza virus in mice as a result of adaptive amino acid substitutions - Fan Yang; Xiaodi Zhang; Fumin Liu; Hangping Yao; Nanping Wu; Haibo Wu (Virus Genes, 2022)

Outcrop modeling of flow units and reductant within a sandstone uranium reservoir in the Zhiluo Formation, eastern Ordos Basin: implications for the uranium mineralization mechanism - Zhenpeng Tao; Liqun Wu; Yangquan Jiao; Hui Rong; Fan Zhang; Xuesong Lu (Geosciences Journal, 2022)

Siccirubricoccus soli sp. nov., a novel bacterial species isolated from Jiaozi Mountain soil - Guo-Xing Zhu; Ya-Jie Wu; Yan-Ru Cao; Bing-Jun Fan; Yu Jiao; Xiu-Li Hou; Zi-Chao Liu; Yue Zhang; Jiang-Bo He; Lian-Ming Liang (Antonie van Leeuwenhoek, 2022)

Analysis of urban carbon emission efficiency and influencing factors in the Yellow River Basin - Weifeng Gong; Haixia Zhang; Chuanhui Wang; Bin Wu; Yaqi Yuan; Shengjie Fan (Environmental Science and Pollution Research, 2022)

Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway - Jie Shen; Xiushan Wu; Ping Zhu; Jian Zhuang; Bin Qin; Fang Sun; Wuzhou Yuan; Xiongwei Fan; Zhigang Jiang; Fang Li; Yongqing Li; Yuequn Wang; et al. (Human Cell, 2022)

A fungal mycelium elicitor efficiently improved ginsenoside synthesis during adventitious root culture of Panax ginseng - X. L. An; Y. Yu; M. Z. Fan; X. H. Wu; X. F. Li; X. C. Piao; M. L. Lian (Journal of Plant Biochemistry and Biotechnology, 2022)

Improving Potato Yield, Water Productivity and Nitrogen Use Efficiency by Managing Irrigation Based on Potato Root Distribution - Lan Wu; Li Li; Zhong Ma; Mingshou Fan (International Journal of Plant Production, 2022)
Potato is a typical shallow-root crop and a good understanding of its root distribution is critical in potato water management, which is especially important for potato production in areas such as Inner Mongolia where water resource is limited. We conducted field experiments to investigate the dynamic distribution of potato root in the soil, then used this as a basis to design a new irrigation method for potato production in the region; effects of the improved irrigation and conventional method were analyzed as well by measuring plant growth, yield, water productivity and nitrogen use efficiency. The results showed that large difference existed in root distribution of potato plants at different growth stages in Inner Mongolia, suggesting the present water management strategy of uniform irrigation during potato production is inefficient and has great potential for improvement. Adjusting irrigation amount so that the wet soil zone depth covered 80% of root distribution during potato growth significantly increased water productivity, decreased N leaching, improved N absorption, nitrogen use efficiency and plant growth, leading to increased tuber yield. Therefore, the improved water management method can be used extensively.

Effects of passenger blockage on smoke flow properties in subway station fires - Fan Wu; Yan Wang; Ru Zhou; Juncheng Jiang (Environmental Science and Pollution Research, 2022)

Investigation on the application of by-product steam in iron ore sintering: performance and function mechanism - Yufeng Wu; Xiaohui Fan; Zhiyun Ji; Min Gan; Haoyu Zhou; Haorui Li; Xuling Chen; Yuanjie Zhao; Rongchang Zhang; Ruisi Lai (Environmental Science and Pollution Research, 2022)

Surface Soil Water Content Before and After Coal Mining and its Influencing Factors—A Case Study of the Daliuta Coal Mine in Shaanxi Province, China - Zhiyuan Wu; Fan Cui; Junli Nie (Mine Water and the Environment, 2022)

Elevated mir-145-5p is associated with skeletal muscle dysfunction and triggers apoptotic cell death in C2C12 myotubes - Jing Jin; Fanyi Li; Caihong Fan; Yu Wu; Chunhui He (Journal of Muscle Research and Cell Motility, 2022)

Disciplinary structure of geographic science in China - Fahu Chen; Xin Li; Shaohong Wu; Jie Fan; Juhua Xiong; Guoyou Zhang (Journal of Geographical Sciences, 2022)

Overexpression of sonic hedgehog enhances the osteogenesis in rat ectomesenchymal stem cells - Weijiang Wu; Zhe Wang; Zhijian Zhang; Wenjing Yang; Xin Fan; Jili Xu; Zhiqiang Huang; Qixiang Shao (Cell and Tissue Banking, 2022)

Correction: Co-axial Projective Imaging for Augmented Reality Telementoring in Skin Cancer Surgery - Fan Zhang; Carlo M. Contreras; Pengfei Shao; Liping Zhao; Bingxuan Wu; Chenmeng Li; Tao Lin; Xiaohong Zhong; Zhongliang Lang; Peng Liu; Ronald X. Xu (Annals of Biomedical Engineering, 2022)

Evaluation of four novel protein sources as alternatives to soybean meal for two specifications of cage-farmed grass carp (Ctenopharyngodon idellus) deeds: Effect on growth performance, flesh quality, and expressions of muscle-related genes - Ze Fan; Chenhui Li; Di Wu; Jinnan Li; Liansheng Wang; Dingchen Cao; Linghong Miao; Shouqi Xie (Frontiers in Marine Science, 2022)
Costs associated with the use of soybean as a food source in aquaculture have imposed constraints on its use in this industry. Thus, research is now focusing on alternative sources of protein for use in aquaculture. Here, we assessed the effect of total replacement of soybean meal (SBM) by Clostridium autoethanogenum protein (CAP), Tenebrio molitor meal (TMM), cottonseed protein concentrate (CPC), and chlorella powder (CHP) in diets for small specimens (initial body weight: 239.72 ± 10.75 g) and large specimens (initial body weight: 638.32 ± 12.64 g) of grass carp. For that purpose, five isonitrogenous (300 g/kg) and isoaliphatic (58 g/kg) diets were formulated with SBM, CAP, TMM, CPC, and CHP as the only dietary protein source. Triplicate groups of fish were fed the experimental diets for 56 days. Results showed that irrespective of protein sources, large specimens of grass carp obtained the significantly reduced weight gain rate (WGR), specific growth rate, moisture, crude ash contents, drip loss rate, and gene expressions of muscle S6K, MyoD, and Myf-5, and the significantly increased crude protein and crude lipid contents, hardness, cohesiveness, adhesiveness, springiness, chewiness and shear force of muscles, and gene expressions of muscle TOR, 4EBP1, MyoG, MRF4, and MSTN-1. Regardless of size, the CHP group possessed markedly higher WGR, protein efficiency ratio, crude protein contents, hardness, adhesiveness, chewiness values, and gene expression levels of muscle TOR, 4EBP1, Myf-5, and MRF4, and significantly lower feed conversion rate, drip loss rate, and gene expressions of muscle S6K and MSTN-1. For small specimens or for large specimens, the essential amino acid contents of the CHP group were highest, and CHP markedly elevated the delicious amino acid and glycine contents in comparison with the SBM. Moreover, the CPC group also realized the function of promoting the growth and improving the flesh quality to a certain degree. However, total replacement of soybean meal by CAP and TMM in grass carp diets restrained the growth and damaged the flesh quality in varying degrees. Overall, comparatively, total replacement of SBM with CHP not only improved growth performance and feed use, but also enhanced the flavor and texture of the fish by improving the amino acid composition and water-holding capacity of muscle, as well as improving muscle growth by positively impacting the expression of genes associated with the regulation of growth and development. Therefore, CHP could be a potential protein source to replace SBM in diets for use in the aquaculture of grass carp.

Human Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorate Skin Aging of Nude Mice Through Autophagy-Mediated Anti-Senescent Mechanism - Ting Li; Li Zhou; Mengqiang Fan; Zuxiang Chen; Li Yan; Haishan Lu; Ming Jia; Huiling Wu; Letian Shan (Stem Cell Reviews and Reports, 2022)

Impact of COVID-19 pandemic on the pregnancy outcomes of women undergoing assisted reproductive techniques (ARTs): a systematic review and meta-analysis - Weihuan Hu; Yuhang Zhu; Yan Wu; Fangfang Wang; Fan Qu (Journal of Zhejiang University-SCIENCE B, 2022)

PLXDC2 enhances invadopodium formation to promote invasion and metastasis of gastric cancer cells via interacting with PTP1B - Bin Wu; Yan-xia Wang; Jun-jie Wang; Dong-fang Xiang; Meng-si Zhang; Ze-xuan Yan; Wen-ying Wang; Jing-ya Miao; Xi Lan; Jia-jia Liu; Zheng-yan Li; Chuan Li; et al. (Clinical & Experimental Metastasis, 2022)
Plexin-domain containing 2 (PLXDC2) has been reported as an oncoprotein in several human malignancies. However, its expression and roles in gastric cancer remain largely unclear. In this study, we found that PLXDC2 was highly expressed in gastric cancer tissues, and the expression levels were positively correlated with clinicopathological features, but negatively with the patients’ outcome. Cox regression analysis identified PLXDC2 as an independent prognostic indicator for the patients. Knockdown of PLXDC2 markedly suppressed the in vitro invasion and in vivo metastasis of gastric cancer cells, while overexpression of PLXDC2 resulted in opposite effects. Mechanistically, PLXDC2 enhanced the level of phosphorylated Cortactin (p-Cortactin) by physically interacting with protein tyrosine phosphatase 1B (PTP1B), an important dephosphorylase, to prevent its dephosphorylating of p-Cortactin, thereby promoting the formation of invadopodia. Collectively, our results indicate that PLXDC2 contributes to the invasion and metastasis of gastric cancer by inhibiting PTP1B to facilitate the invadopodium formation, and may serve as a potential prognostic biomarker and a therapeutic target for this disease.

Molecular characteristics and pathogenicity of an equid alphaherpesvirus 1 strain isolated in China - Yue Hu; Qinrui Jia; Jianhua Liu; Wencheng Sun; Zilei Bao; Chuanzhong Che; Guiling Wu; Bin Fan; Jarhen; Duoliang Ran (Virus Genes, 2022)

Modified catalytic performance of Lactobacillus fermentum l-lactate dehydrogenase by rational design - Aiai Wu; Yajun Bai; TaiPing Fan; Xiaohui Zheng; Yujie Cai (Systems Microbiology and Biomanufacturing, 2022)

The impacts of ambient relative humidity and temperature on supine position-related obstructive sleep apnea in adults - Wen-Te Liu; Yuan-Hung Wang; Li-Te Chang; Chih-Da Wu; Dean Wu; Cheng-Yu Tsai; Chen-Chen Lo; Kang Lo; Kian Fan Chung; Ta-Yuan Chang; Kai-Jen Chuang; Yueh-Lun Lee; et al. (Environmental Science and Pollution Research, 2022)

Equation of state of elbaite at high pressure up to 21.1 GPa and room temperature - Wei Chen; Shijie Huang; Zhilin Ye; Jiamei Song; Shanrong Zhang; Mengzeng Wu; Dawei Fan; Wenge Zhou (Physics and Chemistry of Minerals, 2022)

The functional evolution and system equilibrium of urban and rural territories - Jie Fan; Sisi Li; Zhongrui Sun; Rui Guo; Kan Zhou; Dong Chen; Jianxiong Wu (Journal of Geographical Sciences, 2022)

Streptococcus vulneris sp. nov., isolated from wound of patient with diabetic foot ulcer (DFU) - Jen-hao Chung; Li-Ting Wang; Yi-Sheng Chen; Yun-Shien Lee; Shih-Ting Lin; Yu-Chung Chang; Hui-Chung Wu; Yu-Jie Dai; Wei-Qi Liao; Fan-Ching Kao; Jui-hsiang Li (Archives of Microbiology, 2022)

Application of enzymatic hydrolysate of Ulva clathrata as biostimulant improved physiological and metabolic adaptation to salt-alkaline stress in wheat - Feiyu Li; Zhihua Wu; Siqi Zuo; Li Fan; Zhengpeng Wei; Ling Ma; Wenke Sun; Chunying Du; Ruizhi Liu; Peng Wang (Journal of Applied Phycology, 2022)

Investigating the effect of compaction on the anaerobic digestion process of rice straw - Guang-Yin Chen; Hai-Nan Cao; Xue-Qian Fan; Yi-Chen Sun; Jing Wang; Jin-Zhu Dong; Pei Wu (BioEnergy Research, 2022)

Research for type 2 diabetes mellitus in endemic arsenism areas in central China: role of low level of arsenic exposure and KEAP1 rs11545829 polymorphism - Chenlu Fan; Zaihong Zhan; Xin Zhang; Qun Lou; Ning Guo; Mengyao Su; Yue Gao; Ming Qin; Liaowei Wu; Wei Huang; Meichen Zhang; Fanshuo Yin; et al. (Archives of Toxicology, 2022)

Liver transcriptome analyses of acute poisoning and recovery of male ICR mice exposed to the mushroom toxin α-amanitin - Zhijun Wu; Haijiao Li; Yizhe Zhang; Chunguang Ding; Wenjin Zhao; Jing Dai; Chengmin Yu; Qunmei Yao; Fenshuang Zheng; Jingguang Fan; Chengye Sun (Archives of Toxicology, 2022)

Bacteria in biofloc technology aquaculture systems: roles and mediating factors - Godwin Abakari; Xia Wu; Xi He; Lipeng Fan; Guozhi Luo (Reviews in Aquaculture, 2022)
The abundance of nitrogen compounds, phosphorous compounds and organic matter in biofloc technology (BFT) aquaculture systems creates an ideal medium for increasing microbial communities and load. The abundance of microbial DNA found in BFT aquaculture systems is hypothesised to be among the greatest in current aquaculture systems. Several factors mediate the bacterial diversity, relative abundance and dynamics in BFT systems. This review focusses on the bacteria in BFT aquaculture systems, their role as food for animals present in the culture and their various relationships with major nutrients. The analytical techniques available for determining bacterial integrity and function are reviewed along with the factors that affect microbial community structure, water quality and production performance. Future investigations to characterise bacteria in BFT aquaculture systems and their roles and mediating factors are suggested.

Volcanic rocks of the Elashan Formation in the Dulan-Xiangride Basin, East Kunlun Orogenic Belt, NW China: Petrogenesis and implications for Late Triassic geodynamic evolution - Xingzhu Fan; Fengyue Sun; Chenghan Xu; Dongqian Wu; Lu Yu; Li Wang; Cheng Yan; Shahzad Bakht (International Geology Review, 2022)

Linking phytosterols and oxyphytosterols from food to brain health: origins, effects, and underlying mechanisms - Fan Jie; Xuan Yang; Lipeng Wu; Mengmeng Wang; Baiyi Lu (Critical Reviews in Food Science and Nutrition, 2022)

Combination analysis of single-molecule long-read and Illumina sequencing provides insights into the anthocyanin accumulation mechanism in an ornamental grass, Pennisetum setaceum cv. Rubrum - Lingyun Liu; Ke Teng; Xifeng Fan; Chao Han; Hui Zhang; Juying Wu; Zhihui Chang (Plant Molecular Biology, 2022)

Archaeal diversity in the seawater of Changjiang River estuary reveals its adaptability to bottom seawaters - Yan Huang; Wu Qu; Yingping Fan; Jianxin Wang (Journal of Oceanology and Limnology, 2022)

Rapid LC–MS/MS detection of different carbapenemase types in carbapenemase-producing Enterobacterales - Gen Li; Zhihan Ye; Wenyan Zhang; Nianzhen Chen; Yangqin Ye; Yuchao Wang; Fei Wu; Keli Wang; Lieying Fan (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Association between glucagon-like peptide-1 receptor gene polymorphism and treatment response to GLP1R agonists in Chinese patients with type 2 diabetes: a prospective cohort study - Ziwan Guan; Yue Du; Rui Li; Shufang Zhang; Yuedong Xu; Xiaoqian Zhang; Fan Zhang; Ying Yin; Kunrong Wu; Xiaoli Li; Yan Li (European Journal of Clinical Pharmacology, 2022)

Field measurement and numerical simulation of dust migration in a high-rise building of the mine hoisting system - Xinyue Feng; Fan Geng; Haixu Teng; Changgeng Gui; Siqi Wu; Shihang Li; Fubao Zhou; Shilong Yuan (Environmental Science and Pollution Research, 2022)

Fluoride contamination, spatial variation, and health risk assessment of groundwater using GIS: a high-density survey sampling in Weifang City, North China - Jiutan Liu; Yuanyuan Ma; Zongjun Gao; Yuqi Zhang; Zengbing Sun; Tianzhu Sun; Haibin Fan; Bin Wu; Mingbo Li; Lili Qian (Environmental Science and Pollution Research, 2022)

Exogenous H2S Ameliorates High Salt-Induced Hypertension by Alleviating Oxidative Stress and Inflammation in the Paraventricular Nucleus in Dahl S Rats - Yingying Liao; Yuanyuan Fan; Qinglin He; Yuwei Li; Dongdong Wu; Enshe Jiang (Cardiovascular Toxicology, 2022)
Hydrogen sulfide (H 2 S) is an important gaseous signaling molecule that regulates cardiovascular activity in animals. The hypothalamic paraventricular nucleus (PVN) is a major integrative region involved in blood pressure (BP) regulation. We explored whether exogenous H 2 S application by intraperitoneal injection of sodium hydrosulfide (NaHS) alleviates BP increase induced by a high salt diet (HSD) and the role of PVN in Dahl salt-sensitive ( Dahl S ) rats. Dahl S rats were divided into four groups according to diet regime (normal salt diet [NSD] and HSD) and treatment method (daily intraperitoneal NaHS or saline injection). We monitored BP, food and water intake, and body weight for 8 weeks. Plasma, kidney, and brain tissues were collected at the end of the experiment. We found that exogenous H 2 S not only delayed BP elevation but also attenuated the increase in the levels of norepinephrine, cystatin C, and blood urea nitrogen in the plasma of Dahl S rats with an HSD. Furthermore, H 2 S enhanced the total antioxidant capacity, superoxide dismutase, and glutathione peroxidase in the PVN. Exogenous H 2 S attenuated the protein expression of the nuclear factor-κB pathway and proinflammatory cytokines, which were significantly higher in the PVN in rats with an HSD than in rats with an NSD. Additionally, exogenous H 2 S relieved PVN neuronal apoptosis induced by an HSD. These findings suggest that exogenous H 2 S attenuates hypertension caused by an HSD by ameliorating oxidative stress, inflammation, and apoptosis in the PVN. This study provides evidence of the benefits of peripheral H 2 S therapy for hypertension.

Fast and sensitive graphene oxide‐DNAzyme‐based biosensor for Vibrio alginolyticus detection - Xueqing Tian; Jinfei Hu; Tong Wei; Wen Ding; Qingzhen Miao; Zhe Ning; Shihui Fan; Hangjie Wu; Jing Lu; Mingsheng Lyu; Shujun Wang (Journal of Fish Diseases, 2022)
DNAzymes have been widely and effectively used for the detection of pathogenic bacteria, which pose a serious public health threat. However, the rapid and cost‐effective detection of such bacteria remains a major challenge. In this study, we successfully selected Vibrio alginolyticus ‐specific DNAzymes. The activity of the candidates was assessed via fluorescence intensity and gel electrophoresis. The DNAzyme DT1 had a detection limit of 31 CFU/ml for V. alginolyticus and exhibited high specificity. Graphene oxide (GO) was used to develop a DNAzyme‐based fluorescent sensor for the detection of V. alginolyticus , which significantly improved detection performance and shortened the reaction time as little as 10 s. The proposed method was then validated using crab, shrimp, fish, clam, and oyster samples. This study thus provides a new method for the rapid and sensitive detection of V. alginolyticus .

On the Response of Zhejiang Coastal Waters to 12 Typhoons from 2011 to 2015 - Yunhe Pan; Anzhou Cao; Yuqian Wu; Shiming Lu; Luteng Fan; Peiliang Li (Journal of Marine Science and Engineering, 2022)
Based on the hybrid coordinate ocean model (HYCOM) reanalysis data, the dynamical and thermal response of Zhejiang coastal waters to 12 typhoons from 2011 to 2015 was studied, and the relationship between the oceanic response and typhoon characteristics was analyzed. The HYCOM reanalysis data were validated by satellite-observed sea surface temperature data. Results show that all the 12 typhoons caused near-inertial waves, sea surface cooling and seafloor warming, but significant differences existed among them. Based on statistics, it was found that the domain-averaged near-inertial kinetic energy and seafloor warming are significantly correlated with the typhoon’s maximum wind speed, both of which show a positive relationship. The domain-averaged seafloor warming also decreases with the typhoon’s translation speed. Moreover, there exists a positive correlation between the domain-averaged sea surface cooling and seafloor warming. The different mechanisms that caused the seafloor warming for the 12 typhoons were also investigated in this study.

A new cyclopeptide alkaloid from Clematis Florida - Ying Wu; Yi-Fan Zhang; Hai-Tao Zhang; Xin-Hua Ma; Na-Na Yang; Shi-Biao Feng; Tian-Hua Zhong; Yong-Hong Zhang (Natural Product Research, 2022)

Migration and Deposition Characteristics of Particles in Sand Layers with Fluctuating Water Levels - Xianze Cui; Tao Wen; Jin Li; Dazhou Wu; Yong Fan; Ying Jin; Siyuan He; Yucong Pan (Water, Air, & Soil Pollution, 2022)

Lineage tracing reveals the origin of Nestin-positive cells are heterogeneous and rarely from ependymal cells after spinal cord injury - Xiaoyu Xue; Muya Shu; Zhifeng Xiao; Yannan Zhao; Xing Li; Haipeng Zhang; Yongheng Fan; Xianming Wu; Bing Chen; Bai Xu; Yaming Yang; Weiyuan Liu; et al. (Science China Life Sciences, 2022)

Anterior Cingulate Cortex Mediates Hyperalgesia and Anxiety Induced by Chronic Pancreatitis in Rats - Dan Ren; Jia-Ni Li; Xin-Tong Qiu; Fa-Ping Wan; Zhen-Yu Wu; Bo-Yuan Fan; Ming-Ming Zhang; Tao Chen; Hui Li; Yang Bai; Yun-Qing Li (Neuroscience Bulletin, 2022)
Central sensitization is essential in maintaining chronic pain induced by chronic pancreatitis (CP), but cortical modulation of painful CP remains elusive. Here, we examined the role of the anterior cingulate cortex (ACC) in the pathogenesis of abdominal hyperalgesia in a rat model of CP induced by intraductal administration of trinitrobenzene sulfonic acid (TNBS). TNBS treatment resulted in long-term abdominal hyperalgesia and anxiety in rats. Morphological data indicated that painful CP induced a significant increase in FOS-expressing neurons in the nucleus tractus solitarii (NTS) and ACC, and some FOS-expressing neurons in the NTS projected to the ACC. In addition, a larger portion of ascending fibers from the NTS innervated pyramidal neurons, the neural subpopulation primarily expressing FOS under the condition of painful CP, rather than GABAergic neurons within the ACC. CP rats showed increased expression of vesicular glutamate transporter 1, and increased membrane trafficking and phosphorylation of the N -methyl-D-aspartate receptor (NMDAR) subunit NR2B and the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) subunit GluR1 within the ACC. Microinjection of NMDAR and AMPAR antagonists into the ACC to block excitatory synaptic transmission significantly attenuated abdominal hyperalgesia in CP rats, which was similar to the analgesic effect of endomorphins injected into the ACC. Specifically inhibiting the excitability of ACC pyramidal cells via chemogenetics reduced both hyperalgesia and comorbid anxiety, whereas activating these neurons via optogenetics failed to aggravate hyperalgesia and anxiety in CP rats. Taken together, these findings provide neurocircuit, biochemical, and behavioral evidence for involvement of the ACC in hyperalgesia and anxiety in CP rats, as well as novel insights into the cortical modulation of painful CP, and highlights the ACC as a potential target for neuromodulatory interventions in the treatment of painful CP.

Evaluation of historical CMIP6 model simulations and future projections of temperature over the Pan-Third Pole region - Xuewei Fan; Qingyun Duan; Chenwei Shen; Yi Wu; Chang Xing (Environmental Science and Pollution Research, 2022)
The Pan-Third Pole (PTP) region, which encompasses the Eurasian highlands and their surroundings, has experienced unprecedented, accelerated warming during the past decades. This study evaluates the performance of historical simulation runs of the Coupled Model Intercomparison Project (CMIP6) in capturing spatial patterns and temporal variations observed over the PTP region for mean and extreme temperatures. In addition, projected changes in temperatures under four Shared Socioeconomic Pathway (SSP) scenarios (SSP1‐2.6, SSP2‐4.5, SSP3-7.0, and SSP5‐8.5) are also reported. Four indices were used to characterize changes in temperature extremes: the annual maximum value of daily maximum temperature (TXx), the annual minimum value of daily minimum temperature (TNn), and indices for the percentage of warm days (TX90p) and warm nights (TN90p). Results indicate that most CMIP6 models generally capture the characteristics of the observed mean and extreme temperatures over the PTP region, but there still are slight cold biases in the Tibetan Plateau. Future changes of mean and extreme temperatures demonstrate that a strong increase will occur for the entire PTP region during the twenty-first century under all four SSP scenarios. Between 2015 and 2099, ensemble area-averaged annual mean temperatures are projected to increase by 1.24 °C/100 year, 3.28 °C/100 year, 5.57 °C/100 year, and 7.40 °C/100 year for the SSP1-2.6, SSP2-4.5, SSP3-7.0, and SSP5-8.5 scenarios, respectively. For TXx and TNn, the most intense warming is projected in Central Asia. The greatest number of projected TX90p and TN90p will occur in the Southeast Asia and Tibetan Plateau, respectively.

Origin of Dispersed Organic Matter within Sandstones and Its Implication for Uranium Mineralization: A Case Study from Dongsheng Uranium Ore Filed in China - Fan Zhang; Yangquan Jiao; Shuangming Wang; Liqun Wu; Hui Rong (Journal of Earth Science, 2022)

Markers and Genetic Mechanisms of Primary and Epigenetic Oxidation of an Aeolian Depositional System of the Luohandong Formation, Ordos Basin - Yao Xiang; Yangquan Jiao; Liqun Wu; Hui Rong; Fan Zhang (Journal of Earth Science, 2022)

Functional traits explain the consistent resistance of biodiversity to plant invasion under nitrogen enrichment - Shao‐peng Li; Pu Jia; Shu‐ya Fan; Yingtong Wu; Xiang Liu; Yani Meng; Yue Li; Wen‐sheng Shu; Jin‐tian Li; Lin Jiang (Ecology Letters, 2022)
Elton's biotic resistance hypothesis, which posits that diverse communities should be more resistant to biological invasions, has received considerable experimental support. However, it remains unclear whether such a negative diversity–invasibility relationship would persist under anthropogenic environmental change. By using the common ragweed ( Ambrosia artemisiifolia ) as a model invader, our 4‐year grassland experiment demonstrated consistently negative relationships between resident species diversity and community invasibility, irrespective of nitrogen addition, a result further supported by a meta‐analysis. Importantly, our experiment showed that plant diversity consistently resisted invasion simultaneously through increased resident biomass, increased trait dissimilarity among residents, and increased community‐weighted means of resource‐conservative traits that strongly resist invasion, pointing to the importance of both trait complementarity and sampling effects for invasion resistance even under resource enrichment. Our study provides unique evidence that considering species’ functional traits can help further our understanding of biotic resistance to biological invasions in a changing environment.

Flexural performances of pre-stressed concrete piles reinforced with hybrid BFRP and steel bars - Ping Wu; Yang Guo; Dayong Zhu; Weiliang Jin; Chack-fan Lee (European Journal of Environmental and Civil Engineering, 2022)

Hypoglycemic and hypolipidemic effects of sugar beet (Beta vulgaris L.) extract on C57BL/KsJ db/db mice - Zhipan Wu; Haitao Gong; Yuhang Shen; Haote Han; Wei Zhu; Jingkui Tian; Hua Fan; Shouxin Li (Rendiconti Lincei. Scienze Fisiche e Naturali, 2022)

Assessment of potential sediment disasters and resilience management of mountain roads using environmental indicators - Chao-Yuan Lin; Yuan-Chung Lai; Shao-Wei Wu; Fan-Chung Mo; Cheng-Yu Lin (Natural Hazards, 2022)
In recent years, extreme rainfall events occur frequently, causing serious watershed sediment disasters, destroying mountain roads, and endangering the safety of residents' lives and property. This study aims to deal with the spatial change of potential sediment movement on the road slope pre-disaster and to screen disaster hot spots for early warning and control system. The conceptual model is used to simulate the distribution of primary and/or derived disasters on a watershed scale to assess the impact of sediment disasters caused by heavy rain event. Correlation analysis shows that the models in assessment of primary disaster and derived disaster are significantly correlated with the collapse ratio and disaster ratio, respectively. Since the primary disaster has been considered when calculating the derived disaster risk, the terrain subdivision along Provincial Highway 21 (Tai-21) is extracted to understand the derived sediment disaster on the road slope. The model can effectively evaluate the road sections prone to disasters. According to the risk level, the hot spot of road slope disasters and the management of disaster resilience are determined and can be the reference for disaster prevention and control.

Administration of rTMS Alleviates Stroke-Induced Cognitive Deficits by Modulating miR-409-3p/CTRP3/AMPK/Sirt1 Axis - Tianya Wu; Chunrong Tang; Junwei Fan; Jian Tao (Journal of Molecular Neuroscience, 2022)

Correction to: Data-driven analysis and evaluation of regional agriculture for high quality development of Anhui Province in the Yangtze River Delta - Fan Liu; Cui Wang; Yingyan Zhang; Shuling Zhou; Yaliu Yang; Xue Wu; Fagang Hu; Conghu Liu (Environmental Science and Pollution Research, 2022)

Data-driven analysis and evaluation of regional agriculture for high-quality development of Anhui Province in the Yangtze River Delta - Fan Liu; Cui Wang; Yingyan Zhang; Shuling Zhou; Yaliu Yang; Xue Wu; Fagang Hu; Conghu Liu (Environmental Science and Pollution Research, 2022)

Acute exposure to paraquat affects the phenotypic differentiation of substantia nigra microglia in rats - Wendi Zhang; Xiaobei Fan; Zhuo Fan; Bailin Wu; Mengchao Wang; Wanyu Duan; Bo Song (Environmental Science and Pollution Research, 2022)

A numerical model for landslide movement - Yunyun Fan; Fengyuan Wu (Bulletin of Engineering Geology and the Environment, 2022)

Groundwater source identification based on principal component analysis and improved extreme learning machine algorithm using the genetic algorithm: a case study from the Dagushan iron mine, Liaoning Province, China - Qian Hao; Xiong Wu; Wenping Mu; Fan Yu (Arabian Journal of Geosciences, 2022)

Mesoporous Silica Carrier-Based Composites for Taste-Masking of Bitter Drug: Fabrication and Palatability Evaluation - Weifeng Zhang; Guoxiang Li; Chaoqiang Xiao; Xin Chang; Ying Sun; Weiping Fan; Bing Tian; Di Gao; Yao Xiao; Xueping Wu; Shuwang He; Guangxi Zhai (AAPS PharmSciTech, 2022)

Sugarcane Breeding, Germplasm Development and Related Molecular Research in China - Yongwen Qi; Xiaoning Gao; Qiaoying Zeng; Zhao Zheng; Caiwen Wu; Rongzhong Yang; Xiaomin Feng; Zilin Wu; Lina Fan; Zhenghui Huang (Sugar Tech, 2022)

Long-term, multidomain analyses to identify the breed and allelic effects in MSTN-edited pigs to overcome lameness and sustainably improve nutritional meat production - Ziyao Fan; Zhiguo Liu; Kui Xu; Tianwen Wu; Jinxue Ruan; Xinmin Zheng; Shideng Bao; Yulian Mu; Tad Sonstegard; Kui Li (Science China Life Sciences, 2022)

Single-cell RNA sequencing reveals Nestin+ active neural stem cells outside the central canal after spinal cord injury - Muya Shu; Xiaoyu Xue; Hu Nie; Xianming Wu; Minghan Sun; Lianyong Qiao; Xing Li; Bai Xu; Zhifeng Xiao; Yannan Zhao; Yongheng Fan; Bing Chen; et al. (Science China Life Sciences, 2022)

Loss of O-GlcNAcylation on MeCP2 at Threonine 203 Leads to Neurodevelopmental Disorders - Juanxian Cheng; Zhe Zhao; Liping Chen; Ying Li; Ruijing Du; Yan Wu; Qian Zhu; Ming Fan; Xiaotao Duan; Haitao Wu (Neuroscience Bulletin, 2022)

Effects of protein oxidation, cathepsins, and various freezing temperatures on the quality of superchilled sturgeon fillets - Nana Zhao; Xianqing Yang; Yujin Li; Haohao Wu; Yiping Chen; Ruichang Gao; Feng Xiao; Fan Bai; Jinlin Wang; Zunying Liu; Xin Gao; Yuanhui Zhao (Marine Life Science & Technology, 2022)

Development of molecular markers based on LTR retrotransposon in the Cleistogenes songorica genome - Tiantian Ma; Xingyi Wei; Yufei Zhang; Jie Li; Fan Wu; Qi Yan; Zhuanzhuan Yan; Zhengshe Zhang; Gisele Kanzana; Yufeng Zhao; Yingbo Yang; Jiyu Zhang (Journal of Applied Genetics, 2022)

Astrocytic modulation on neuronal electric mode selection induced by magnetic field effect - Zhixuan Yuan; Peihua Feng; Yongchen Fan; Yangyang Yu; Ying Wu (Cognitive Neurodynamics, 2022)

Investigation of Antibiotic-Resistant Bacterial Communities and Antibiotic-Resistant Genes in Wastewater Treatment Plants: Removal of Antibiotic-Resistant Genes by the BBR Process - Zi-fan Weng; Yu-qin He; Guo-xiang Li; Xiao-tong Wu; Yi Dai; Peng Bao (Bulletin of Environmental Contamination and Toxicology, 2022)

Drivers of Regional Environmental Pollution Load and Zoning Control: A Case Study of the Yangtze River Economic Belt, China - Kan Zhou; Jianxiong Wu; Jie Fan; Hanchu Liu (Chinese Geographical Science, 2022)

Preface to the Special Issue: Climate Change and Variability of Tropical Cyclone Activity - Liguang Wu; Bin Wang; Johnny C. L. Chan; Kyung-Ja Ha; Il-Ju Moon; Jun Matsumoto; Zhemin Tan; Ke Fan (Advances in Atmospheric Sciences, 2022)

Formation of the Huajiang Grand Canyon (southwestern China) driven by the evolution of a Late Pleistocene tiankeng - Yunlong Fan; Andrea Columbu; Kangning Xiong; Guangjie Luo; Song Li; Xuefeng Wang; Yangyang Wu (Acta Geochimica, 2022)

Tropical tall forests are more sensitive and vulnerable to drought than short forests - Liyang Liu; Xiuzhi Chen; Philippe Ciais; Wenping Yuan; Fabienne Maignan; Jin Wu; Shilong Piao; Ying‐Ping Wang; Jean‐Pierre Wigneron; Lei Fan; Pierre Gentine; Xueqin Yang; et al. (Global Change Biology, 2022)
Our limited understanding of the impacts of drought on tropical forests significantly impedes our ability in accurately predicting the impacts of climate change on this biome. Here, we investigated the impact of drought on the dynamics of forest canopies with different heights using time‐series records of remotely sensed Ku‐band vegetation optical depth (Ku‐VOD), a proxy of top‐canopy foliar mass and water content, and separated the signal of Ku‐VOD changes into drought‐induced reductions and subsequent non‐drought gains. Both drought‐induced reductions and non‐drought increases in Ku‐VOD varied significantly with canopy height. Taller tropical forests experienced greater relative Ku‐VOD reductions during drought and larger non‐drought increases than shorter forests, but the net effect of drought was more negative in the taller forests. Meta‐analysis of in situ hydraulic traits supports the hypothesis that taller tropical forests are more vulnerable to drought stress due to smaller xylem‐transport safety margins. Additionally, Ku‐VOD of taller forests showed larger reductions due to increased atmospheric dryness, as assessed by vapor pressure deficit, and showed larger gains in response to enhanced water supply than shorter forests. Including the height‐dependent variation of hydraulic transport in ecosystem models will improve the simulated response of tropical forests to drought.

The adjoint-based Two Oceans One Sea State Estimate (TOOSSE) - Xiaowei Wang; Chuanyu Liu; Armin Köhl; Wu Geng; Fan Wang; Detlef Stammer (Journal of Oceanology and Limnology, 2022)

Retraction Note to: Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes - Michael Nothnagel; Guangyao Fan; Fei Guo; Yongfeng He; Yiping Hou; Shengping Hu; Jiang Huang; Xianhua Jiang; Wook Kim; Kicheol Kim; Chengtao Li; Hui Li; et al. (Human Genetics, 2022)

Exploratory analysis of the associations between urinary phytoestrogens and thyroid hormones among adolescents and adults in the United States: National Health and Nutrition Examination Survey 2007–2010 - Yun Fan; Hong Qian; Zhuo Wu; Zhi Li; Xiuzhu Li; Yan Zhang; Qiaoqiao Xu; Chuncheng Lu; Xinru Wang (Environmental Science and Pollution Research, 2022)

Molecular epidemiology of type I and II feline coronavirus from cats with suspected feline infectious peritonitis in China between 2019 and 2021 - Lishan Lin; Dawei Yao; Lei Wu; Rubin Fan; Yang Liu; Zhenlei Zhou (Archives of Virology, 2022)

Effect of feed restriction on the intestinal microbial community structure of growing ducks - Jun-peng Li; Qi-fan Wu; Sheng-chao Ma; Jian-mei Wang; Bin Wei; Yang Xi; Chun-chun Han; Liang Li; Hua He; He-he Liu (Archives of Microbiology, 2022)

Comparison of the Anthropogenic Emission Inventory for CMIP6 Models with a Country-Level Inventory over China and the Simulations of the Aerosol Properties - Tianyi Fan; Xiaohong Liu; Chenglai Wu; Qiang Zhang; Chuanfeng Zhao; Xin Yang; Yanglian Li (Advances in Atmospheric Sciences, 2022)

Environmental drivers of phytoplankton crops and taxonomic composition in northeastern Antarctic Peninsula adjacent sea area - Yubin Feng; Dong Li; Jun Zhao; Zhengbing Han; Jianming Pan; Gaojing Fan; Haisheng Zhang; Ji Hu; Haifeng Zhang; Jiaqi Wu; Qiuhong Zhu (Acta Oceanologica Sinica, 2022)

Optimization and Application of an Efficient and Stable Inhalation Exposure System for Rodents - Zi Fan; Bo Zhou; Yujia Liu; Wu Sun; Yuntao Fang; Hongguo Lu; Dongya Chen; Kuikui Lu; Xinyue Wu; Tian Xiao; Wenjing Xie; Qian Bian (AAPS PharmSciTech, 2022)

Temperature sensitivity of anaerobic methane oxidation versus methanogenesis in paddy soil: Implications for the CH 4 balance under global warming - Lichao Fan; Michaela A. Dippold; Volker Thiel; Tida Ge; Jinshui Wu; Yakov Kuzyakov; Maxim Dorodnikov (Global Change Biology, 2022)
The global methane (CH 4 ) budget is based on a sensitive balance between methanogenesis and CH 4 oxidation (aerobic and anaerobic). The response of these processes to climate warming, however, is not quantified. This largely reflects our lack of knowledge about the temperature sensitivity ( Q 10 ) of the anaerobic oxidation of CH 4 (AOM)—a ubiquitous process in soils. Based on a 13 CH 4 labeling experiment, we determined the rate, Q 10 and activation energy of AOM and of methanogenesis in a paddy soil at three temperatures (5, 20, 35°C). The rates of AOM and of methanogenesis increased exponentially with temperature, whereby the AOM rate was significantly lower than methanogenesis. Both the activation energy and Q 10 of AOM dropped significantly from 5–20 to 20–35°C, indicating that AOM is a highly temperature‐dependent microbial process. Nonetheless, the Q 10 of AOM and of methanogenesis were similar at 5–35°C, implying a comparable temperature dependence of AOM and methanogenesis in paddy soil. The continuous increase of AOM Q 10 over the 28‐day experiment reflects the successive utilization of electron acceptors according to their thermodynamic efficiency. The basic constant for Q 10 of AOM was calculated to be 0.1 units for each 3.2 kJ mol −1 increase of activation energy. We estimate the AOM in paddy soils to consume 2.2~5.5 Tg CH 4 per year on a global scale. Considering these results in conjunction with literature data, the terrestrial AOM in total consumes ~30% of overall CH 4 production. Our data corroborate a similar Q 10 of AOM and methanogenesis. As the rate of AOM in paddy soils is lower than methanogenesis, however, it will not fully compensate for an increased methane production under climate warming.

Ubiquitination of p21 by E3 Ligase TRIM21 Promotes the Proliferation of Human Neuroblastoma Cells - Fan Wang; Zerui Wu; Qun Li; Zhihui Ni; Chengde Wang; Jianglong Lu (NeuroMolecular Medicine, 2021)

Major histocompatibility complex class II genetic diversity and the genetic influence on gut microbiota in Guizhou minipigs - Gang Yao; Min Fan; Jian Zhang; Yanjun Wu; Hai Zhao; Hui Zhang; Longfei Li; Shuguang Wu (Folia Microbiologica, 2021)

Adsorption Performance and Mechanism of Synthetic Schwertmannite to Remove Low-Concentration Fluorine in Water - Zehong Zhang; Le Wang; Bo Zhou; Sichang Wang; Lin Fan; Sihai Hu; Yaoguo Wu (Bulletin of Environmental Contamination and Toxicology, 2021)

Enhanced expression of DNA methyltransferase 1-associated protein1 gene thermotolerance in a high-temperature acclimated predatory mite Neoseiulus barkeri - Ya-Ying Li; Chuan-Bei Tian; Yi-Xia Wu; Tian-Di Niu; Hao Wang; Wen-Hui Fan; Huai Liu (BioControl, 2021)

Luteirhabdus pelagi gen. nov., sp. nov., a novel member of the family Flavobacteriaceae, isolated from the West Pacific Ocean - Wen-Ting Ren; Fan-Xu Meng; Li-Li Guo; Li Sun; Xue-Wei Xu; Peng Zhou; Yue-Hong Wu (Archives of Microbiology, 2021)
A Gram-stain-negative, aerobic, and yellow-pigmented bacterium, designated A3-108 T , was isolated from seawater of the West Pacific Ocean. Cells were non-motile and rod-shaped, with carotenoid-type pigments. Strain A3-108 T grew at pH 6.0–8.5 (optimum 6.5) and 15–40 °C (optimum 28 °C), in the presence of 0.5–10% (w/v) NaCl (optimum 1.0%). It possessed the ability to produce H 2 S. Based on the 16S rRNA gene analysis, strain A3-108 T exhibited highest similarity with Aureisphaera salina A6D-50 T (90.6%). Phylogenetic analysis shown that strain A3-108 T affiliated with members of the family Flavobacteriaceae and represented an independent lineage. The principal fatty acids were iso-C 15:0 , iso-C 17:0 3-OH, iso-C 15:1 G, and summed feature 3 (C 16:1 ω 7 c and/or C 16:1 ω 6 c ). The sole isoprenoid quinone was MK-6. The major polar lipids were phosphatidylethanolamine, one unidentified aminophospholipid, one unidentified aminolipid and one unidentified lipid. The ANIb, in silico DDH and AAI values among the genomes of strain A3-108 T and three reference strains were 67.3–71.1%, 18.7–22.1%, and 58.8–71.4%, respectively. The G + C content was 41.0%. Distinctness of the phylogenetic position as well as differentiating chemotaxonomic and other phenotypic traits revealed that strain A3-108 T represented a novel genus and species of the family Flavobacteriaceae , for which the name Luteirhabdus pelagi gen. nov., sp. nov. is proposed (type strain, A3-108 T = CGMCC 1.18821 T = KCTC 82563 T ).

Inhibitory effects of redroot pigweed and crabgrass on switchgrass germination and growth—from lab to field - Xincun Hou; Xu Hu; Yuesen Yue; Qiang Guo; Chunqiao Zhao; Xifeng Fan; Juying Wu (Plant Ecology, 2021)

Mutation of the sixth amino acid of the Rep protein has no effect on porcine circovirus 2b but enhances porcine circovirus 2d replication in vitro - Xiaoyan Wu; Shuo Wang; Changxun Xin; Chen Li; Jianli Shi; Zhe Peng; Chang Liu; Hong Han; Ying Yang; Yao Tian; Jiaxin Li; Shaojian Xu; et al. (Archives of Virology, 2021)

Streptococcus vaginalis sp. nov., a novel bacterial species isolated from vaginal swabs of a pregnant woman with diabetes - An-Shine Chao; Chiao-Yun Lin; Angel Chao; Yun-Shien Lee; Yu-Chung Chang; Hui-Chung Wu; Yu-Jie Dai; Wei-Qi Liao; Fan-Ching Kao; Yi-Sheng Chen (Archives of Microbiology, 2021)

Corrigendum: The Effects of Storage in vitro on Functions, Transcriptome, Proteome, and Oxidation Resistance of Giant Grouper Sperm - Yang Yang; Tong Wang; Sen Yang; Xi Wu; Wenhua Huang; Bin Fan; Junhong Xia; Zining Meng; Xiaochun Liu (Frontiers in Marine Science, 2021)

Design and Development of Tracked Sugarcane Transporter - Tao Wu; Hebin Wu; Qingting Liu; Xiaoling Liang; Qiuju Fan; Cong Xie (Sugar Tech, 2021)

Sustained growth of the largest uninhabited alluvial island in the Changjiang Estuary under the drastic reduction of river discharged sediment - Xiaodong Zhang; Rui Xie; Daidu Fan; Zuosheng Yang; Hongmin Wang; Chuang Wu; Yuhan Yao (Science China Earth Sciences, 2021)

Genome-wide development and application of miRNA-SSR markers in Melilotus genus - Gisele Kanzana; Jean Musaza; Fan Wu; Zifeng Ouyang; Yimeng Wang; Tiantian Ma; Bakhit Ishag Rahama Akoy; Jiyu Zhang (Physiology and Molecular Biology of Plants, 2021)

Updated taxonomy of Chinese Phylloporus (Boletaceae, Boletales): six new taxa and four redescribed species - Lu-Ling Wu; Zhi-Qun Liang; Ming-Sheng Su; Yu-Guang Fan; Ping Zhang; Shuai Jiang; Yan-Liu Chen; Yan-Jia Hao; Nian-Kai Zeng (Mycological Progress, 2021)

Increased uterine androgen receptor protein abundance results in implantation and mitochondrial defects in pregnant rats with hyperandrogenism and insulin resistance - Yuehui Zhang; Min Hu; Fan Yang; Yizhuo Zhang; Shuting Ma; Dongqi Zhang; Xu Wang; Amanda Nancy Sferruzzi-Perri; Xiaoke Wu; Mats Brännström; Linus R. Shao; Håkan Billig (Journal of Molecular Medicine, 2021)
In this study, we show that during normal rat pregnancy, there is a gestational stage-dependent decrease in androgen receptor (AR) abundance in the gravid uterus and that this is correlated with the differential expression of endometrial receptivity and decidualization genes during early and mid-gestation. In contrast, exposure to 5α-dihydrotestosterone (DHT) and insulin (INS) or DHT alone significantly increased AR protein levels in the uterus in association with the aberrant expression of endometrial receptivity and decidualization genes, as well as disrupted implantation. Next, we assessed the functional relevance of the androgen-AR axis in the uterus for reproductive outcomes by treating normal pregnant rats and pregnant rats exposed to DHT and INS with the anti-androgen flutamide. We found that AR blockage using flutamide largely attenuated the DHT and INS-induced maternal endocrine, metabolic, and fertility impairments in pregnant rats in association with suppressed induction of uterine AR protein abundance and androgen-regulated response protein and normalized expression of several endometrial receptivity and decidualization genes. Further, blockade of AR normalized the expression of the mitochondrial biogenesis marker Nrf1 and the mitochondrial functional proteins Complexes I and II, VDAC, and PHB1. However, flutamide treatment did not rescue the compromised mitochondrial structure resulting from co-exposure to DHT and INS. These results demonstrate that functional AR protein is an important factor for gravid uterine function. Impairments in the uterine androgen-AR axis are accompanied by decreased endometrial receptivity, decidualization, and mitochondrial dysfunction, which might contribute to abnormal implantation in pregnant PCOS patients with compromised pregnancy outcomes and subfertility. Key messages The proper regulation of uterine androgen receptor (AR) contributes to a normal pregnancy process, whereas the aberrant regulation of uterine AR might be linked to polycystic ovary syndrome (PCOS)-induced pregnancy-related complications. In the current study, we found that during normal rat pregnancy there is a stage-dependent decrease in AR abundance in the gravid uterus and that this is correlated with the differential expression of the endometrial receptivity and decidualization genes Spp1 , Prl , Igfbp1 , and Hbegf . Pregnant rats exposed to 5α-dihydrotestosterone (DHT) and insulin (INS) or to DHT alone show elevated uterine AR protein abundance and implantation failure related to the aberrant expression of genes involved in endometrial receptivity and decidualization in early to mid-gestation. Treatment with the anti-androgen flutamide, starting from pre-implantation, effectively prevents DHT + INS-induced defects in endometrial receptivity and decidualization gene expression, restores uterine mitochondrial homeostasis, and increases the pregnancy rate and the numbers of viable fetuses. This study adds to our understanding of the mechanisms underlying poor pregnancy outcomes in PCOS patients and the possible therapeutic use of anti-androgens, including flutamide, after spontaneous conception.

Hydrochemical characteristics of groundwater and evaluation of water quality in arid area of Northwest China: a case study in the plain area of Kuitun River Basin - Zhang Fuchu; Wu Bin; Gao Fan; Du Mingliang; Xu Liantong (Arabian Journal of Geosciences, 2021)

Changes of Extreme Precipitation and its Associated Mechanisms in Northwest China - Shan Lu; Zeyong Hu; Haipeng Yu; Weiwei Fan; Chunwei Fu; Di Wu (Advances in Atmospheric Sciences, 2021)

Experimental study on integrated and autonomous conductivity-temperature-depth (CTD) sensor applied for underwater glider - Bin Lv; Hai-lin Liu; Yi-fan Hu; Cheng-xuan Wu; Jie Liu; Hai-jing He; Jie Chen; Jian Yuan; Zhao-wen Zhang; Lin Cao; Hui Li (Marine Georesources & Geotechnology, 2021)

Magnetic Resonance Imaging-Guided and Navigated Individualized Repetitive Transcranial Magnetic Stimulation for Cognitive Impairment in Schizophrenia - Xu-Sha Wu; Tian-Cai Yan; Xian-Yang Wang; Yang Cao; Xiao-Fan Liu; Yu-Fei Fu; Lin Wu; Yin-Chuan Jin; Hong Yin; Long-Biao Cui (Neuroscience Bulletin, 2021)

Gastrodin Regulates the Notch Signaling Pathway and Sirt3 in Activated Microglia in Cerebral Hypoxic-Ischemia Neonatal Rats and in Activated BV-2 Microglia - Jing Guo; Xiao-Li-Na Zhang; Zhang-Rui Bao; Xue-Ke Yang; Ling-Shuang Li; Yu Zi; Fan Li; Chun-Yun Wu; Juan-Juan Li; Yun Yuan (NeuroMolecular Medicine, 2021)

Potential economic impact of invasive fall armyworm on mainly affected crops in China - Pengxiang Wu; Fengming Wu; Jingyu Fan; Runzhi Zhang (Journal of Pest Science, 2021)

Study on the comprehensive utilization of solid residues of Flammulina velutipes and vinegar and their application as feed in Eisenia fetida earthworm culture - Tong Xu; Fan Fei; Yangyang Ding; Yongchao Liu; Guanghua Mao; Liuqing Yang; Ting Zhao; Taotao Liao; Weiwei Feng; Xiangyang Wu (Environmental Science and Pollution Research, 2021)

The Wind Effect on Biogeochemistry in Eddy Cores in the Northern South China Sea - Chun Hoe Chow; Yung-Yen Shih; Ya-Tang Chien; Jing Yi Chen; Ning Fan; Wei-Chang Wu; Chin-Chang Hung (Frontiers in Marine Science, 2021)
Cyclonic and anticyclonic eddies are usually characterized by upwelling and downwelling, respectively, which are induced by eddy pumping near their core. Using a repeated expendable bathythermograph transect (XBT) and Argo floats, and by cruise experiments, we determined that not all eddies in the northern South China Sea (NSCS) were accompanied by eddy pumping. The weakening of background thermocline was attributed to the strengthening of eddy pumping, affected by (1) wind-induced meridional Sverdrup transports and (2) Kuroshio intrusion into the NSCS. Higher particulate organic carbon (POC) fluxes (> 100 mg-C m −2 day −1 ) were found near the eddy cores with significant eddy pumping (defined by a depth change of 22°C isotherm near the thermocline for over 10 m), although the satellite-estimated POC fluxes were inconsistent with the in-situ POC fluxes. nitrogen limitation transition and high POC flux were even found near the core of a smaller mesoscale (diameter < 100 km) cyclonic eddy in May 2014, during the weakening of the background thermocline in the NSCS. This finding provides evidence that small mesoscale eddies can efficiently provide nutrients to the subsurface, and that they can remove carbon from the euphotic zone. This is important for global warming, which generally strengthens upper ocean stratification.

A whole-genome association approach for large-scale interspecies traits - Huizhong Fan; Lei Chen; Yibo Hu; Guohui Shi; Yi Dai; Fuwen Wei; Qi Wu (Science China Life Sciences, 2021)

Correction to: MiR-26a regulated adipogenic differentiation of ADSCs induced by insulin through CDK5/FOXC2 pathway - Xu-Xiang Zhang; Yu-Ming Wang; Yan-Dan Su; Fan Zuo; Bin Wu; Xin Nian (Molecular and Cellular Biochemistry, 2021)

Involvement of Putrescine, Nitric Oxide, and Hydrogen Peroxide in Methyl Jasmonate-Induced Ginsenoside Synthesis in Adventitious Root Cultures of Panax ginseng C.A. Meyer - Xiao-Han Wu; Ming-Zhi Fan; Xue-Feng Li; Xuan-Chun Piao; Ri Gao; Mei-Lan Lian (Journal of Plant Growth Regulation, 2021)

A novel index of functional connectivity: phase lag based on Wilcoxon signed rank test - Xuan Li; Yunqiao Wu; Mengting Wei; Yiyun Guo; Zhenhua Yu; Haixian Wang; Zhanli Li; Hui Fan (Cognitive Neurodynamics, 2021)

Well logging curve reconstruction based on kernel ridge regression - Pengpeng Fan; Rui Deng; Jinquan Qiu; Zhongliang Zhao; Shengli Wu (Arabian Journal of Geosciences, 2021)

Dietary magnesium requirement on dietary minerals and physiological function of juvenile hybrid sturgeon (Acipenser schrenckii♀ × Acipenser baerii♂) - Yuanyuan Zhang; Ze Fan; Di Wu; Jinnan Li; Qiyou Xu; Hongbai Liu; Liansheng Wang (Aquaculture International, 2021)
Sturgeons are an economically important freshwater aquacultural fish in China and elsewhere. Research was conducted to study the magnesium requirement of juvenile hybrid sturgeon ( Acipenser schrenckii ♀ × Acipenser baerii ♂) based on mineral composition, proximate chemical analysis, antioxidant enzyme levels, and growth metrics. Different levels of magnesium supplements (43.2, 157.3, 326.5, 549.6, 743.9, 938.4, and 1118.2 mg kg −1 ) were fed to juvenile sturgeon for 8 weeks. Five hundred twenty-five juvenile hybrid sturgeons (an average initial body weight of 7.65 g) were randomly divided into 7 groups with 3 replicates each (25 fish per replicate, tanks of 100×50×50 cm, dissolved oxygen ≥ 5.0 mg L −1 , 12 light:12 dark) and fed 4 times per day with the experimental diets containing 40.78% crude protein and 10.03% crude fat. The body tissues and blood of fish were then sampled and analyzed. Growth performance was not significantly different between treatments ( P> 0.05). The optimal dietary magnesium requirement for hybrid sturgeon was estimated to be 355.16, 573.6, or 584.6 mg kg −1 dietary magnesium based on whole-body Mg retention, the whole-body or vertebrae magnesium content versus dietary magnesium levels. The whole-body calcium to phosphorus ratio of the 43.2 and 326.5 mg kg −1 groups was significantly higher than that of the 938.4 mg kg −1 group ( P −1 improved the antioxidant capacity by decreasing the serum malondialdehyde and enhancing serum superoxide dismutase, glutathione peroxidase, and catalase activities.

Lysobacter enzymogenes antagonizes soilborne bacteria using the type IV secretion system - Xi Shen; Bingxin Wang; Nianda Yang; Lulu Zhang; Danyu Shen; Huijun Wu; Ying Dong; Ben Niu; Shan‐Ho Chou; Gerardo Puopolo; Jiaqin Fan; Guoliang Qian (Environmental Microbiology, 2021)
Summary Soil microbiome comprises numerous microbial species that continuously interact with each other. Among the modes of diverse interactions, cell–cell killing may play a key role in shaping the microbiome composition. Bacteria deploy various secretion systems to fend off other microorganisms and Type IV Secretion System (T4SS) in pathogenic bacteria was shown to function as a contact‐dependent, inter‐bacterial killing system only recently. The present study investigated the role played by T4SS in the killing behaviour of the soilborne biocontrol bacterium Lysobacter enzymogenes OH11. Results showed that L . enzymogenes OH11 genome encompasses genes encoding all the components of T4SS and effectors potentially involved in inter‐bacterial killing system. Generation of knock‐out mutants revealed that L . enzymogenes OH11 uses T4SS as the main contact‐dependent weapon against other soilborne bacteria. The T4SS‐mediated killing behaviour of L . enzymogenes OH11 decreased the antibacterial and antifungal activity of two Pseudomonas spp. but at the same time, protected carrot from infection by Pectobacterium carotovorum . Overall, this study showed for the first time the involvement of T4SS in the killing behaviour of L . enzymogenes and its impact on the multiple interactions occurring in the soil microbiome.

The Effects of Storage in vitro on Functions, Transcriptome, Proteome, and Oxidation Resistance of Giant Grouper Sperm - Yang Yang; Tong Wang; Sen Yang; Xi Wu; Wenhua Huang; Bin Fan; Junhong Xia; Zining Meng; Xiaochun Liu (Frontiers in Marine Science, 2021)
Asynchrony of sexual maturity is a huge limitation in the reproduction of grouper sperm. Cold storage of sperm is an effective method to solve the problem of asynchronization. However, sperms gradually lose their activity with the prolonged storage time in vitro . In order to explore causes, the effects of cold storage on transcriptome, proteome and oxidation resistance of giant grouper sperm were analyzed. Firstly, the absolute RNA quantity and consistent transcripts existed in each spermatozoon were estimated. With the prolonged storage, the RNA quantity gradually decreased both in the cytoplasm and in the mitochondria of the spermatozoon. The decreased transcripts were mainly enriched with energy metabolism and stress response. Similar to RNAs, the absolute protein quantity was also significantly decreased during the storage of sperm. Decreased proteins were mainly enriched with the oxidative phosphorylation pathway. Proteins involved in the oxidative phosphorylation showed a faster degradation rate compared to the average total protein. In addition, the oxidation resistance and adenosine triphosphate (ATP) contents showed a significant decrease in the sperm during storage in vitro . These results implied that damages of transcriptome, proteome, and oxidation resistance have negative effects on the normal functions of sperm, especially their energy metabolism. The present study provides essential foundation for improving the storage of sperm in vitro .

The Effects on Water Particle Velocity of Wave Peaks Induced by Nonlinearity under Different Time Scales - Aifeng Tao; Shuya Xie; Di Wu; Jun Fan; Yini Yang (Journal of Marine Science and Engineering, 2021)
The water particle velocity of the wave peaks is closely related to the wave load borne by offshore structures. It is of great value for marine disaster prevention to study the water particle velocity of nonlinear extreme waves represented by Freak waves. This study applies the High-order Spectral Method (HOS) numerical model to analyze the characteristics and influencing factors of the water particle velocity of Freak wave peak with two different generation mechanisms under the initial condition of a weakly modulated Stokes wave train. Our results show that the water particle velocity of the wave peak increases linearly with wave height and initial wave steepness in the evolution stage of modulation instability. While in the later stage, the relationship becomes exponential. Under the condition of similar wave heights, the deformation degrees of Freak waves with different generation mechanisms are distinct, the deformation degree of modulation instability stage is smaller than that of the later stage. The water particle velocity of the wave peaks increases with the deformation degrees. Furthermore, the correlation between wave peak height and water particle velocity is a quadratic function. This provides a theoretical basis for further understanding of nonlinear waves and the prediction of marine disasters.

Comparison of Representative Heuristic Algorithms for Multi-Objective Reservoir Optimal Operation - Wenzhuo Wang; Benyou Jia; Slobodan P. Simonovic; Shiqiang Wu; Ziwu Fan; Li Ren (Water Resources Management, 2021)

Coupling loss characteristics of N-P-C through runoff and sediment in the hilly region of SE China under simulated rainfall - Longzhou Deng; Tianyu Sun; Kai Fei; Liping Zhang; Xiaojuan Fan; Yanhong Wu; Liang Ni; Rui Sun (Environmental Science and Pollution Research, 2021)

Using seismic sedimentology in delineating a distributary channel type shallow-water lacustrine delta: first member of the Cretaceous Yaojia Formation in Changling area, South of Songliao Basin - Jun Wang; Kai Zeng; Bowen Wu; Jianzheng Ji; Zhidong Bao; Bin Cheng; Hongjing Zhang; Ping Xiong; Fan Diao (Arabian Journal of Geosciences, 2021)

Identification, expression and enzyme activity of the group III sPLA 2 s in Cyprinus carpio L - Yuxin Xu; Hongxia Li; Dihui Xu; Jianlin Li; Fan Yu; Meiyao Wang; Qin Wang; Yunsheng Wu; Qiyuan Zhang; Yongkai Tang; Juhua Yu (Journal of Fish Biology, 2021)
Five group III secreted phospholipase (pla2g3s) homologous genes located on different linkage groups were identified from common carp ( Cyprinus carpio ), which we named Ccpla2g3a1 , Ccpla2g3a2 , Ccpla2g3b , Ccpla2g3c1 and Ccpla2g3c2 . The five genes encode 530, 525, 461, 752 and 753 amino acids, respectively. Sequence analysis showed that the Ccpla2g3a s contain seven exons and the others contain four exons. Synteny analysis of fish pla2g3s indicated that pla2g3a and pla2g3b were from the same ancestor gene, and Ccpla2g3a 1, Ccpla2g3a 2, Ccpla2g3c 1 and Ccpla2g3c 2 were from the specific genome duplication of common carp. Due to the significant variation of the pla2g3bs from common carp and zebrafish ( Danio rerio ), they formed a separate group in the phylogenetic tree. The tissue distributions of Ccpla2g3 s coincided with their expression profiles during the embryo stages. The expression levels of Ccpla2g3a s and Ccpla2g3c s were low at the embryo stages, and they were abundant in the liver and brain, respectively, whereas the expression of Ccpla2g3b was high at 0.5 h after fertilization and in the ovary. We obtained three soluble recombinant proteins of the bee venom‐like PLA2 (BVLP) from Ccpla2g3 and evaluated their PLA 2 enzyme properties. The optimum pHs of MBP‐a1‐BVLP, MBP‐b‐BVLP and MBP‐c1‐BVLP were 7.5, 7.0 and 8.0, respectively, and specific activities were 7.68 ± 0.66, 4.155 ± 0.158 and 1.93 ± 0.05 U μmol –1 , respectively. The K d for Ca 2+ of MBP‐b‐BVLP was the lowest (2.6 μM), whereas the values for both MBP‐a1‐BVLP and MBP‐c1‐BVLP were about 15 μM. The K m values of three proteins ranged from 31.9 to 41.91 μM.

Quantitative Proteomics Analysis of Sugarcane Ratoon Crop Chlorosis - Ye-Geng Fan; Rong-Fa Chen; Li-Hang Qiu; Zhong-Feng Zhou; Hui-Wen Zhou; Ji-Guang Wei; Xiu-Peng Song; Ting Luo; Prakash Lakshmanan; Xing Huang; Jian-Ming Wu; Yang-Rui Li (Sugar Tech, 2021)

Influence of cold-storage of eggs of Menochilus sexmaculatus (Coleoptera: Coccinellidae) on the biology and predatory efficiency - QingHeng Tian; YongMei Fan; Muhammad Musa Khan; Jianhui Wu; Liangde Tang (International Journal of Tropical Insect Science, 2021)

Research on the Formation and Development of Plastic Zones in Surrounding Rocks of Roadways Containing Gas - Lei Fan; Weijun Wang; Chao Yuan; Hai Wu; Wenqing Peng (Geotechnical and Geological Engineering, 2021)

The influence of recipient SLCO1B1 rs2291075 polymorphism on tacrolimus dose–corrected trough concentration in the early period after liver transplantation - Yi Wu; Fang Fang; Zhaowen Wang; Peihao Wen; Junwei Fan (European Journal of Clinical Pharmacology, 2021)
Purpose To explore the relationship between rs2291075 polymorphism in SLCO1B1 gene, which encodes an influx transmembrane protein transporter, and tacrolimus dose–corrected trough concentration (C/D, ng ml −1 mg −1 kg −1 ) in the early period after liver transplantation. Methods CYP3A5 rs776746 and SLCO1B1 rs2291075 polymorphisms of 210 liver transplantation patients and their corresponding donor livers were assessed by PCR amplification and DNA sequencing. The influence of gene polymorphisms on C/D values of tacrolimus was analyzed. The early postoperative period after liver transplantation was divided into the convalescence phase (1–14 days) and stationary phase (15–28 days) according to the change of liver function and tacrolimus C/D values. Results The combined analysis of donor and recipient CYP3A5 rs776746 could distinguish the metabolic phenotype of tacrolimus into three groups: fast elimination (FE), intermediate elimination (IE), and slow elimination (SE), which was entitled the FIS classification system. Tacrolimus C/D ratios of recipient SLCO1B1 rs2291075 CT and TT carriers were very close and were significantly lower than those of recipient SLCO1B1 rs2291075 CC genotype carriers in convalescence phase ( p = 0.0195) and in stationary phase ( p = 0.0152). There were no statistically significant differences between tacrolimus C/D ratios of patients carried with SLCO1B1 rs2291075 CT, TT genotype donors, and those carried with SLCO1B1 rs2291075 CC genotype donors. A model consisting of tacrolimus daily dose, total bilirubin, FIS classification, and recipient SLCO1B1 rs2291075 could predict tacrolimus C/D ratios in the convalescence phase by multivariate analysis. However, recipient SLCO1B1 rs2291075 genotype failed to enter forecast model for C/D ratios in stationary phase. Recipient SLCO1B1 rs2291075 genotype had significant effect on tacrolimus C/D ratios in convalescence phase ( p = 0.0300) and stationary phase ( p = 0.0400) in subgroup, which excluded the interference come from donor and recipient CYP3A5 rs776746. Conclusion SLCO1B1 rs2291075 could be a novel genetic locus associated with tacrolimus metabolism. The combined analysis of donor and recipient CYP3A5 rs776746, recipient SLCO1B1 rs2291075 genotypes, could be helpful to guide the personalized administration of tacrolimus in early period after liver transplantation.

Correction to: Effects of zinc oxide nanoparticles on arsenic stress in rice (Oryza sativa L.): germination, early growth, and arsenic uptake - Fan Wu; Qing Fang; Shiwei Yan; Ling Pan; Xianjin Tang; Wenling Ye (Environmental Science and Pollution Research, 2021)

Hydrolysis Kinetics of a Novel 3,4-Dichloroisothiazole Plant-Activator Candidate LY5-24-2 by UPLC-Q-TOF - Shuangyu Song; Chengkui Qiao; Lijun Han; Hanzhong Xie; Yingying Bi; Fayi Qin; Qifan Wu; Yuedong Li; Zhijin Fan (Bulletin of Environmental Contamination and Toxicology, 2021)

Effects of high temperature on the mechanical behaviors of sandstone under true-triaxial unloading conditions - Fan Xiao; Deyi Jiang; Fei Wu; Quanle Zou; Jie Chen; Bo Chen; Zhongguang Sun (Bulletin of Engineering Geology and the Environment, 2021)

Optimization of microfine-cement-based slurry containing microfine fly ash and nano-CaCO3 for microfracture grouting - Shuai Zhang; Wei-Guo Qiao; Yue Wu; Zhen-Wang Fan; Lei Zhang (Bulletin of Engineering Geology and the Environment, 2021)

Seismic behaviour of a steel-reinforced concrete inclined column transfer structure under different axial force ratios - Jiyang Zhang; Yuhui Fan; Shiming Zhou; Bo Shen; Kejian Ma; Hongmei Wu; Bo Liu (Arabian Journal of Geosciences, 2021)

Probiotics supplementation improves hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes mellitus: An update of meta-analysis - Tingting Liang; Lei Wu; Yu Xi; Ying Li; Xinqiang Xie; Congcong Fan; Lingshuang Yang; Shuanghong Yang; Xuefeng Chen; Jumei Zhang; Qingping Wu (Critical Reviews in Food Science and Nutrition, 2021)

Antifungal Effect of Long Noncoding RNA 9708-1 in the Vulvovaginal Candidiasis Murine Model - Ying Wu; Lisha Jiang; Lingling Zhang; Xia Liu; Lina Yan; Ting Luan; Can Rui; Zhiyuan Mao; Chong Fan; Yu Liu; Ping Li; Xin Zeng (Mycopathologia, 2021)
Vulvovaginal candidiasis (VVC) caused by Candida spp. affects 70–75% of women at least once during their lives. We aim to elucidate the potential mechanism of VVC and investigate the therapeutic effects of long noncoding RNA 9708-1. Female BALB/c mice were randomized to four treatment groups, including the blank control group, VVC control group, vehicle control group and lncRNA 9708-1-overexpressed group. Mice were euthanized on Day 4, Day 7 and Day 14 after treatment. Colony-forming unit (CFU) was measured, and the inflammation was detected by hematoxylin and eosin (H&E). Gene and protein expression levels of lncRNA 9708-1 and FAK were determined by real-time PCR, Western blot and immunohistochemistry. The overexpression of lncRNA 9708-1 significantly decreased the fungal load from Day 4 to 7. H&E staining indicated that the impaired histological profiles were improved in lncRNA 9708-1-overexpressed group. LncRNA 9708-1 led to a significant increase in FAK level of vagina tissue which is expressed mainly in epithelial basal layer. This study suggests that lncRNA 9708-1 played a protective role on murine experimental VVC by upregulating the expression levels of FAK.

Dual-Specificity Phosphatase 15 (DUSP15) Modulates Notch Signaling by Enhancing the Stability of Notch Protein - Noopur Bhore; Bo-Jeng Wang; Po-Fan Wu; Yen-Lurk Lee; Yun-Wen Chen; Wen-Ming Hsu; Hsinyu Lee; Yi-Shuian Huang; Ding-I Yang; Yung-Feng Liao (Molecular Neurobiology, 2021)

Isolation and genetic characteristics of a neurotropic teschovirus variant belonging to genotype 1 in northeast China - Hailong Ma; Mengjia Zhang; Meizhou Wu; Ahmed.H. Ghonaim; Shengxian Fan; Qigai He (Archives of Virology, 2021)

Global scale life cycle environmental impacts of single- and multi-walled carbon nanotube synthesis processes - Sila Temizel-Sekeryan; Fan Wu; Andrea L. Hicks (The International Journal of Life Cycle Assessment, 2021)

Development and Application of Cutterhead Working Status Monitoring System for Shield TBM Tunnelling - Qiuming Gong; Fan Wu; Dujuan Wang; Haifeng Qiu; Lijun Yin (Rock Mechanics and Rock Engineering, 2021)

Metabolite analysis reveals distinct spatio-temporal accumulation of anthocyanins in two teinturier variants of cv. ‘Gamay’ grapevines (Vitis vinifera L.) - Junhua Kong; Jing Wu; Le Guan; Ghislaine Hilbert; Serge Delrot; Peige Fan; Zhenchang Liang; Benhong Wu; José Tomás Matus; Eric Gomès; Zhanwu Dai (Planta, 2021)

MiR-26a regulated adipogenic differentiation of ADSCs induced by insulin through CDK5/FOXC2 pathway - Xu-Xiang Zhang; Yu-Ming Wang; Yan-Dan Su; Fan Zuo; Bin Wu; Xin Nian (Molecular and Cellular Biochemistry, 2021)

Transgenic eukaryotic microalgae as green factories: providing new ideas for the production of biologically active substances - Qianwen Shi; Cheng Chen; Wei Zhang; Ping Wu; Meng Sun; Hui Wu; Haizhen Wu; Pengcheng Fu; Jianhua Fan (Journal of Applied Phycology, 2021)

Dynamics of leukocyte telomere length in adults aged 50 and older: a longitudinal population-based cohort study - Zhezhou Huang; Chazhen Liu; Ye Ruan; Yanfei Guo; Shuangyuan Sun; Yan Shi; Fan Wu (GeroScience, 2021)

Structural network performance for early diagnosis of spastic cerebral palsy in periventricular white matter injury - Haoxiang Jiang; Heng Liu; Tingting Huang; Liang Wu; Fan Wu; Congcong Liu; Miaomiao Wang; Chao Jin; Jian Yang; Xianjun Li (Brain Imaging and Behavior, 2021)

In vitro regeneration of the colorful fern Pteris aspericaulis var. tricolor via green globular bodies system - Rongpei Yu; Fan Li; Guoxian Wang; Jiwei Ruan; Lifang Wu; Min Wu; Chunmei Yang; Qinli Shan (In Vitro Cellular & Developmental Biology - Plant, 2021)

Isolation and characterization of two novel reassortant H5N6 avian influenza viruses from waterfowl in eastern China - Fan Yang; Yixin Xiao; Fumin Liu; Hangping Yao; Nanping Wu; Haibo Wu (Archives of Virology, 2021)

Human endogenous retrovirus W family envelope protein (HERV-W env) facilitates the production of TNF-α and IL-10 by inhibiting MyD88s in glial cells - Xiuling Wang; Xiulin Wu; Jin Huang; Haiyan Li; Qiujin Yan; Fan Zhu (Archives of Virology, 2021)

Effect of Nonlinear Deformational Macrojoint on Stress Wave Propagation Through a Double-Scale Discontinuous Rock Mass - L. F. Fan; M. Wang; Z. J. Wu (Rock Mechanics and Rock Engineering, 2021)

A novel of transforming wastewater pollution into resources for desertification control by sand-consolidating cyanobacteria, Scytonema javanicum - Qiuheng Zhu; Li Wu; Guowen Li; Xiaoguang Li; Chen Zhao; Caili Du; Fan Wang; Wei Li; Lieyu Zhang (Environmental Science and Pollution Research, 2021)

A single nucleotide polymorphism variant located in the cis ‐regulatory region of the ABCG2 gene is associated with mallard egg colour - Hehe Liu; Jian Hu; Zhanbao Guo; Wenlei Fan; Yaxi Xu; Suyun Liang; Dapeng Liu; Yunsheng Zhang; Ming Xie; Jing Tang; Wei Huang; Qi Zhang; et al. (Molecular Ecology, 2021)
Avian egg coloration is shaped by natural selection, but its genetic basis remains unclear. Here, we used genome‐wide association analysis and identity by descent to finely map green egg colour to a 179‐kb region of Chr4 based on the resequencing of 352 ducks ( Anas platyrhynchos ) from a segregating population resulting from the mating of Pekin ducks (white‐shelled eggs) and mallards (green‐shelled eggs). We further narrowed the candidate region to a 30‐kb interval by comparing genome divergence in seven indigenous duck populations. Among the genes located in the finely mapped region, only one transcript of the ABCG2 gene (XM_013093252.2) exhibited higher uterine expression in green‐shelled individuals than in white‐shelled individuals, as supported by transcriptome data from four populations. ABCG2 has been reported to encode a protein that functions as a membrane transporter for biliverdin. Sanger sequencing of the whole 30‐kb candidate region (Chr4: 47.41–47.44 Mb) and a plasmid reporter assay helped to identify a single nucleotide polymorphism (Chr4: 47,418,074 G>A) located in a conserved predicted promoter region whose variation may alter ABCG2 transcription activity. We provide a useful molecular marker for duck breeding and contribute data to the research on ecological evolution based on egg colour patterns among birds.

Soil Moisture Estimation based on the Distributed Scatterers Adaptive Filter over the QTP Permafrost Region using Sentinel-1 and High-resolution TerraSAR-X Data - Xuefei Zhang; Hong Zhang; Chao Wang; Yixian Tang; Bo Zhang; Fan Wu; Jing Wang; Zhengjia Zhang (International Journal of Remote Sensing, 2021)

Comparison of Long-Term Outcomes of Endoscopic and Minimally Invasive Catheter Evacuation for the Treatment of Spontaneous Cerebellar Hemorrhage - Leiyang Li; Haixiao Liu; Jianing Luo; Zhijun Tan; Junmei Gao; Ping Wang; Wenting Jing; Ruixi Fan; Xiaoyang Zhang; Hao Guo; Hao Bai; Wenxing Cui; et al. (Translational Stroke Research, 2021)
Recently, minimally invasive techniques, including endoscopic evacuation and minimally invasive catheter (MIC) evacuation, have been used for the treatment of patients with spontaneous cerebellar hemorrhage (SCH). However, credible evidence is still needed to validate the effects of these techniques. To explore the long-term outcomes of both surgical techniques in the treatment of SCH. Fifty-two patients with SCH who received endoscopic evacuation or MIC evacuation were retrospectively reviewed. Six-month mortality and the modified Rankin Scale (mRS) score were the primary and secondary outcomes, respectively. A multivariate logistic regression model was used to assess the effects of the different surgical techniques on patient outcomes. In the present study, the mortality rate for the entire cohort was 34.6%. Univariate analysis showed that the surgical technique and preoperative Glasgow Coma Scale (GCS) score affected 6-month mortality. However, no variables were found to be correlated with 6-month mRS scores. Further multivariate analysis demonstrated that 6-month mortality in the endoscopic evacuation group was significantly lower than that in the MIC evacuation group (OR = 4.346, 95% CI 1.056 to 17.886). The 6-month mortality rate in the preoperative GCS 9–14 group was significantly lower than that in the GCS 3–8 group (OR = 7.328, 95% CI 1.723 to 31.170). Compared with MIC evacuation, endoscopic evacuation significantly decreased 6-month mortality in SCH patients. These preliminary results warrant further large, prospective, randomized studies.

Preparation and Evaluation of a Xanthan Gum–Containing Linezolid Ophthalmic Solution for Topical Treatment of Experimental Bacterial Keratitis - Fan Zhang; Dongmei Jia; Qiqi Li; Mengmeng Zhang; Hongyun Liu; Xianggen Wu (Pharmaceutical Research, 2021)

Deep Placement of Nitrogen Fertilizer Affects Grain Yield, Nitrogen Recovery Efficiency, and Root Characteristics in Direct-Seeded Rice in South China - Yunyan Chen; Pingshan Fan; Zhaowen Mo; Leilei Kong; Hua Tian; Meiyang Duan; Lin Li; Liji Wu; Zaimang Wang; Xiangru Tang; Shenggang Pan (Journal of Plant Growth Regulation, 2021)

First report of Chaetomella raphigera causing brown spot on Eucalyptus urophylla × E. grandis in China - Xiu-Xiu Cao; Ji-Guang Wei; Jian-Gan Hou; Chun-Li Fan; Ji Luo; Yao-Jun Wu; Xiu-Hao Yang; Ji-Tong Luo; Xiao-Bing Yang (Journal of Plant Pathology, 2021)

Reproductive Parameters of Captive Female Northern White-Cheeked (Nomascus leucogenys) and Yellow-Cheeked (Nomascus gabriellae) Gibbons - Penglai Fan; Xin He; Yuzhao Yang; Xuefeng Liu; Haibo Zhang; Li Yuan; Wu Chen; Dingzhen Liu; Pengfei Fan (International Journal of Primatology, 2021)

Germanium fractions in typical paddy soil and its interaction with humic substances - Bolun Fan; Molan Tang; Lingyang Yao; Aobo Zhang; Hanqin Yin; Weilin Yang; Zhenzhen Ma; Wu Xiang; Zhengyu Bao (Environmental Science and Pollution Research, 2021)

Bioaccumulation and risk assessment of heavy metals in soil-crop systems in Liujiang karst area, Southwestern China - Molan Tang; Guanghui Lu; Bolun Fan; Wu Xiang; Zhengyu Bao (Environmental Science and Pollution Research, 2021)

Assessment of uranium migration and pollution sources in river sediments of the Ili River Basin using multiply statistical techniques - Lingfeng Dong; Zhanfei He; Fan Zhang; Tao Xu; Jingyi Wu; Kaifang Yan; Xiangliang Pan; Daoyong Zhang (Environmental Science and Pollution Research, 2021)

Correlation of exosomal microRNA clusters with bone metastasis in non-small cell lung cancer - Xiao-Rong Yang; Can Pi; Ruoying Yu; Xiao-Jun Fan; Xiao-Xiao Peng; Xu-Chao Zhang; Zhi-Hong Chen; Xue Wu; Yang Shao; Yi-Long Wu; Qing Zhou (Clinical & Experimental Metastasis, 2021)
20–40% of lung cancer patients develop bone metastasis (BM) with significantly decreased overall survival. Currently, BM is mainly diagnosed by computerized tomography (CT) scan or magnetic resonance imaging (MRI) when symptom develops. Novel biomarkers with higher prediction value of BM are needed. Plasma-derived exosomal microRNAs had been isolated and sequenced of total 30 non-small cell lung cancer (NSCLC) patients including 16 with bone metastasis and 14 without bone metastasis. Hierarchical clustering based on the total miRNA profile can clearly separate cancer patients and healthy individuals (H), but not patients with (BM +) or without (BM−) BM. Weight Co-expression network of miRNAs (WGCNA) analyses identified three consensus clusters (A, B, C) of highly correlated miRNAs, among which cluster B (144 miRNAs) showed significantly differential expression in lung cancer patients, especially in BM + group. Pathway analysis of cluster B miRNAs revealed enrichment in metabolic pathways that may involve in preconditioning of the metastatic niche. Three differentially expressed miRNAs between BM + and BM− patients within cluster B were identified as miR-574-5p, a suppressor of Wnt/β-catenin pathway, was down-regulated, while miR-328-3p and miR-423-3p, two activators of the same pathway, were up-regulated in BM + patients. Cluster A miRNAs (n = 49) also showed trend of upregulation in BM + patients. Interestingly, pathway analysis indicated that 43 of them are associated with chromosome14, which has been suggested to promote epithelial-mesenchymal transition (EMT) and bone metastasis.

Isolation and characterization of the novel Pseudomonas stutzeri bacteriophage 8P - Xinwu Liu; Zhou Feng; Xiangyu Fan; Yong Nie; Xiao-Lei Wu (Archives of Virology, 2021)

Rapid and highly efficient genomic engineering with a novel iEditing device for programming versatile extracellular electron transfer of electroactive bacteria - Yang‐Yang Fan; Qiang Tang; Yang Li; Feng‐He Li; Jing‐Hang Wu; Wen‐Wei Li; Han‐Qing Yu (Environmental Microbiology, 2021)
Summary The advances in synthetic biology bring exciting new opportunities to reprogram microorganisms with novel functionalities for environmental applications. For real‐world applications, a genetic tool that enables genetic engineering in a stably genomic inherited manner is greatly desired. In this work, we design a novel genetic device for rapid and efficient genome engineering based on the i ntron‐encoded homing‐endonuclease empowered genome editing (iEditing). The iEditing device enables rapid and efficient genome engineering in Shewanella oneidensis MR‐1, the representative strain of the electroactive bacteria group. Moreover, combining with the Red or RecET recombination system, the genome‐editing efficiency was greatly improved, up to approximately 100%. Significantly, the iEditing device itself is eliminated simultaneously when genome editing occurs, thereby requiring no follow‐up to remove the encoding system. Then, we develop a new extracellular electron transfer (EET) engineering strategy by programming the parallel EET systems to enhance versatile EET. The engineered strains exhibit sufficiently enhanced electron output and pollutant reduction ability. Furthermore, this device has demonstrated its great potential to be extended for genome editing in other important microbes. This work provides a useful and efficient tool for the rapid generation of synthetic microorganisms for various environmental applications.

Effects of Different Component Contents of Colistin Methanesulfonate on the Pharmacokinetics of Prodrug and Formed Colistin in Human - Ya-Xin Fan; Yuan-Cheng Chen; Yi Li; Ji-Cheng Yu; Xing-Chen Bian; Xin Li; Wan-Zhen Li; Bei-Ning Guo; Hai-Lan Wu; Xiao-Fen Liu; Yu Wang; Xiao-Yong Xu; et al. (Pharmaceutical Research, 2021)

Conditional Deletion of Foxg1 Alleviates Demyelination and Facilitates Remyelination via the Wnt Signaling Pathway in Cuprizone-Induced Demyelinated Mice - Fuxing Dong; Dajin Liu; Feiyu Jiang; Yaping Liu; Xiuxiang Wu; Xuebin Qu; Jing Liu; Yan Chen; Hongbin Fan; Ruiqin Yao (Neuroscience Bulletin, 2021)
The massive loss of oligodendrocytes caused by various pathological factors is a basic feature of many demyelinating diseases of the central nervous system (CNS). Based on a variety of studies, it is now well established that impairment of oligodendrocyte precursor cells (OPCs) to differentiate and remyelinate axons is a vital event in the failed treatment of demyelinating diseases. Recent evidence suggests that Foxg1 is essential for the proliferation of certain precursors and inhibits premature neurogenesis during brain development. To date, very little attention has been paid to the role of Foxg1 in the proliferation and differentiation of OPCs in demyelinating diseases of the CNS. Here, for the first time, we examined the effects of Foxg1 on demyelination and remyelination in the brain using a cuprizone (CPZ)-induced mouse model. In this work, 7-week-old Foxg1 conditional knockout and wild-type (WT) mice were fed a diet containing 0.2% CPZ w/w for 5 weeks, after which CPZ was withdrawn to enable remyelination. Our results demonstrated that, compared with WT mice, Foxg1 -knockout mice exhibited not only alleviated demyelination but also accelerated remyelination of the demyelinated corpus callosum. Furthermore, we found that Foxg1 knockout decreased the proliferation of OPCs and accelerated their differentiation into mature oligodendrocytes both in vivo and in vitro . Wnt signaling plays a critical role in development and in a variety of diseases. GSK-3β, a key regulatory kinase in the Wnt pathway, regulates the ability of β-catenin to enter nuclei, where it activates the expression of Wnt target genes. We then used SB216763, a selective inhibitor of GSK-3β activity, to further demonstrate the regulatory mechanism by which Foxg1 affects OPCs in vitro . The results showed that SB216763 clearly inhibited the expression of GSK-3β, which abolished the effect of the proliferation and differentiation of OPCs caused by the knockdown of Foxg1 . These results suggest that Foxg1 is involved in the proliferation and differentiation of OPCs through the Wnt signaling pathway. The present experimental results are some of the first to suggest that Foxg1 is a new therapeutic target for the treatment of demyelinating diseases of the CNS.

Improved control of Frankliniella occidentalis on greenhouse pepper through the integration of Orius sauteri and neonicotinoid insecticides - Qing-cai Lin; Hao Chen; Dirk Babendreier; Jin-ping Zhang; Feng Zhang; Xiao-yan Dai; Zuo-wen Sun; Zhao-peng Shi; Xiao-lin Dong; Guang-an Wu; Yi Yu; Li Zheng; et al. (Journal of Pest Science, 2021)

Critical roles of macrophages in pressure overload-induced cardiac remodeling - Dan Yang; Han-Qing Liu; Fang-Yuan Liu; Nan Tang; Zhen Guo; Shu-Qing Ma; Peng An; Ming-Yu Wang; Hai-Ming Wu; Zheng Yang; Di Fan; Qi-Zhu Tang (Journal of Molecular Medicine, 2021)