Linkages Between Optical and Molecular Signatures of Dissolved Organic Matter Along the Yangtze River Estuary-to-East China Sea Continuum - Xingnian Sun; Penghui Li; Yuping Zhou; Chen He; Fang Cao; Yuntao Wang; Quan Shi; Ding He (Frontiers in Marine Science, 2022)
Changes in the molecular composition of dissolved organic matter (DOM) and its light-absorbing component (CDOM) along the river–coastal ocean continuum are crucial for better understanding the source and fate of DOM in coastal oceans. Both optical (absorbance and fluorescence) techniques and ultrahigh-resolution mass spectrometry have been widely used to trace DOM cycling. However, to the best of our knowledge, the linkage between these two techniques is rarely investigated along the river–coastal ocean continuum. In this regard, bulk characterization, optical techniques, and ultrahigh-resolution mass spectrometry [Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS)] were applied to determine the DOM chemistry along a spatial transect from the Yangtze River Estuary (YRE) to the East China Sea. The results showed that DOM in the YRE was mainly controlled by the mixing of freshwater and seawater. Besides terrestrial input, multiple sources (tributary input from the Huangpu River, wastewater input, and sediment resuspension and subsequent release at the turbidity maximum zone) have been identified. In addition, the linkages between CDOM and thousands of formulas were developed based on Spearman’s rank correlations between optical parameters and FT-ICR MS peaks. The linkages showed that the molecular groups associated with the optical parameters generally agreed with conventional biogeochemical interpretations. Nevertheless, each technique has its unique advantage and weakness in interpreting DOM composition. Therefore, the combination of the untargeted FT-ICR MS approach and optical techniques could be valuable for studying the DOM sources and transformation in large river estuarine systems.

Factors Affecting Burrow Architecture of the Polychaete Perinereis Aibuhitensis - Wei He; Jinghui Fang; Yitao Zhang; Yisu Yan; Zhixin Zhang; Junhang Huang; Jianguang Fang; Yuze Mao; Zengjie Jiang; Junwei Wang (Frontiers in Marine Science, 2022)
Bioturbation of infauna plays an important role in the biogeochemical processing of sediments. Infaunal animals build burrows and enlarge the sediment-water interface by their activities and so bioturbation is closely related with burrow structure and animal behavior in the sediment. The purpose of this study is to explore the characteristics of Perinereis aibuhitensis burrow structures with the factors of months and animal sizes (0-1g, 1-2g, 2-3g, 3-4g, and >4g), which would also provide useful knowledge of infauna behavioral ecology. The dimension and complexity of the burrows of P. aibuhitensis were measured by dissecting sediments. The results showed that there were three burrow shapes of P. aibuhitensis , i.e., I, Y and U shapes. Overall, the order of abundance of each of the three burrow shapes were I > Y > U. Larger P. aibuhitensis are inclined to build Y- and U-shaped burrows in June and August. There were significant differences in the tunnel diameter, burrow depth and burrow length separately between different polychaete size classes ( P < 0.001). In February and August, the burrow depths and burrow lengths of P. aibuhitensis individuals with body weights of 1-2 g and 2-3 g were significantly greater than in other months ( P < 0.001). P. aibuhitensis individuals of 1-2 g and 3-4 g body weight had significantly more burrow openings and branches in August than in February ( P < 0.001). Within the same month, the burrow HEindex increased with increasing polychaete size, and when the sizes were 1-2 g, 2-3 g and 3-4 g, the complexity in August was higher than that in other months. This study suggests that I-shaped burrow dominants the burrow architecture of P. aibuhitensis . The polychaete with large size has a higher HEindex (burrow complexity) indicating a strong bioturbation ability. Y-shaped burrows are more conducive to the survival of P. aibuhitensis in hot weather. In order to adapt to environmental stresses outside, P. aibuhitensis usually builds deeper burrows.

Melatonin inhibits Gram-negative pathogens by targeting citrate synthase - Fang He; Yuan Liu; Pan Li; Xiaoyan Wu; Yaoyao Xia; Dong Zhang; Nengzhang Li; Yuanyi Peng; Guoqiang Zhu; Rüdiger Hardeland; Russel J. Reiter; Wenkai Ren (Science China Life Sciences, 2022)

Effects of various spectral compositions on micro-polluted water purification and biofuel feedstock production using duckweed - Qi Li; Zhuolin Yi; Guili Yang; Yaliang Xu; Yanling Jin; Li Tan; Anping Du; Kaize He; Hai Zhao; Yang Fang (Environmental Science and Pollution Research, 2022)

The scale identification associated with priority zone management of the Yangtze River Estuary - Yang Hu; Ning He; Mingxuan Wu; Pengling Wu; Peimin He; Ying Yang; Qinyi Wang; Maoqiu Wang; Shubo Fang (Ambio, 2022)

Effects of bedform migration on nutrient fluxes at the sediment–water interface: a theoretical analysis - Lei Huang; Qifeng Gao; Hongwei Fang; Guojian He; Danny Reible; Dianchang Wang; Xinghua Wu (Environmental Fluid Mechanics, 2022)

Combined game model and investment decision making of power grid-distributed energy system - Yongxiu He; Wei Xiong; Binyou Yang; Hai-yan Yang; Jiu-fang Zhou; Ming-li Cui; Yan Li (Environment, Development and Sustainability, 2022)

Effect of Probiotics on Juvenile Tachypleus tridentatus Gut Microbiota - Kai Xiong; Fengze Miao; Khor Waiho; Ximei Liu; James K. H. Fang; Jinfeng He; Menghong Hu; Youji Wang (Journal of Ocean University of China, 2022)

Genome-wide SNP analysis reveals the selection signatures of two indigenous buffalo breeds in Sichuan - Wei Wang; Donghui Fang; Yi Shi; Fang He; Jia Gan; Maozhong Fu; Xiaodong Deng; Tao Zhang; Hongbing Shen; Shengchao Zhong; Yueda Aguo; Luxi Chen; et al. (Conservation Genetics Resources, 2022)
Sichuan Province spawned abundant of indigenous buffalo varieties, which probably harbor valuable gene resources beneficial to the genetic improvement of buffalo. However, limited genetic information was publicly available. To better understand their selection signatures between different populations, we performed a restriction site-associated DNA sequencing (RADseq) to explore genome-wide SNPs among two indigenous breeds of Sichuan buffaloes. As a result, a total of 2,110,077 high-quality SNPs were finally obtained. Population genetic analysis indicated a obviously genetic differentiation between two breeds. The detection of selective genes showed that 995 and 910 protein-coding genes underwent positive selection in Yibin buffalo (GYBS) and Dechang buffalo (XCS). Further functional analysis revealed distinctly discrepant selection in two breeds. Candidate genes that positively selected from Yibin buffaloes have mainly occurred in functions closely related to meat quality, complex living environment adaption capability, and disease resistance. While they were significantly enriched in cell proliferation and cell components in Dechang buffalo, indicating the selection pressure primarily derived from the requirement of organism growth and development speed during breed formation. Our dataset constitutes a promising reservoir of genome-wide SNP markers of Sichuan buffaloes and provides potentially traits selected in different local populations. Such comprehensive genetic resources offer an unprecedented opportunity for genetic association analysis of economically important traits and precision breeding programs in buffaloes.

A Shuttling Protein Kank1 Plays Important Role in the Sex Determination in Yellow Drum - Sha Sun; Jieping Liu; Sen Zhang; Qiwei He; Wei Han; Kun Ye; Fang Han; Wanbo Li; Zhiyong Wang (Frontiers in Marine Science, 2022)
Sex is one of the most important scientific topics, and the existence of sex dimorphism is a conserved feature in vertebrate taxa. The research on sex-determining genes and sex chromosome evolution is a hot topic in biology. The majority of sex-determining genes expressed in somatic cells, and reciprocal interactions between germ cells and somatic cells, are important for gonadal differentiation. However, the knowledge of how signals are transmitted between somatic cells and germ cells remains unclear. In this study, we confirmed the 36 dph was a sex determination critical stage in yellow drum through transcriptome analysis at the early development stages. We further found that Kank1 participated in the germ cells’ motility process in yellow drum through KEGG pathway analysis together with protein-protein interaction network. With the dual-luciferase reporter assay, we detected that Kank1 increased the transcription of dmrt1_Luc gene in CHO cells and 293T cells. Additionally, we observed that Kank1 was not only expressed in the cytoplasm but also in the nucleus in CHO cells through a fluorescence microscope. These results suggest that Kank1 acts as a shuttling protein as in humans and may play a difunctional role at the early gonad development stage in yellow drum, and it not only participated in the germ cells’ motility but also increased the expression of dmrt1 in yellow drum.

Heterologous expression and characterization of two novel glucanases derived from sheep rumen microbiota - De-Ying Gao; Xiao-Bao Sun; Ying Fang; Bo He; Jun-Hong Wang; Jian-Xin Liu; Jia-Kun Wang; Qian Wang (World Journal of Microbiology and Biotechnology, 2022)

High concentrations of antagonistic bacterial strains from diseased sanqi ginseng rhizosphere suppressed Fusarium root rot - Yaojun Dong; Binbin Tang; Mimi He; Lili Wang; Kai Wu; Sixia Yang; Jianfeng Liu; Hong Yang; Changmei Wang; Fang Yin; Wudi Zhang (European Journal of Plant Pathology, 2022)

Approximate analytical solution for seepage field of drained tunnel in vertically stratified phreatic aquifer - Wei Meng; Chuan He; Fang-yin Wu; Wen-bo Yang; Hao Kou; Zi-han Zhou; De-ping Guo; Hai-long Meng (Journal of Mountain Science, 2022)

Sympathetic Nerve Mediated Spinal Glia Activation Underlies Itch in a Cutaneous T-Cell Lymphoma Model - Fang Tong; Qianru He; Wan-Jie Du; Huan Yang; Dongping Du; Shaofeng Pu; Qingjian Han (Neuroscience Bulletin, 2022)

Cassiterite oxygen isotopes in magmatic-hydrothermal systems: in situ microanalysis, fractionation factor, and applications - Yang Li; Sheng He; Rong-Qing Zhang; Xian-Wu Bi; Lian-Jun Feng; Guo-Qiang Tang; Wen-Zhong Wang; Fang Huang; Xian-Hua Li (Mineralium Deposita, 2022)

Age-related growth responses of birch to warming along an elevational gradient on Changbai Mountain - Xi Qi; Keyan Fang; Haibo Du; Jianan He; Hongshi He; Zhengfang Wu (European Journal of Forest Research, 2022)

Enzyme-Induced Carbonate Precipitation for the Protection of Earthen Dikes and Embankments Under Surface Runoff: Laboratory Investigations - Jia He; Changhang Fang; Xunyu Mao; Yongshuai Qi; Yundong Zhou; Hailei Kou; Liang Xiao (Journal of Ocean University of China, 2022)

Centrifuge modelling of ground-borne vibrations induced by railway traffic in underground tunnels - Yang Wenbo; Qian Zhihao; Tu Jiulin; Zhou Ziyang; Yan Qixiang; Fang Yong; He Chuan (Earthquake Engineering and Engineering Vibration, 2022)

Accessing performance of transport sector considering risks of climate change and traffic accidents: joint bounded-adjusted measure and Luenberger decomposition - Xiaodong Chen; Anda Guo; Jiahao Zhu; Fang Wang; Yanqiu He (Natural Hazards, 2022)

Different Responses of Phytoplankton to the ENSO in Two Upwelling Systems of the South China Sea - Xiaoyan Dang; Yan Bai; Fang Gong; Xiaoyan Chen; Qiankun Zhu; Haiqing Huang; Xianqiang He (Estuaries and Coasts, 2022)

Hearing loss is associated with increased risk of incident stroke but not coronary heart disease among middle-aged and older Chinese adults: the Dongfeng-Tongji cohort study - Liangle Yang; Qin Fang; Lue Zhou; Hao Wang; Handong Yang; Meian He; Zhichao Wang; Weijia Kong; Xiaomin Zhang (Environmental Science and Pollution Research, 2022)

Removal of SO2 from flue gas using blast furnace dust as an adsorbent - Binghua Xie; Na Geng; Qian Yu; Di He; Fang Wang; Tiancheng Liu; Jiyun Gao; Ping Ning; Xin Song; Lijuan Jia (Environmental Science and Pollution Research, 2022)

High-resolution sea surface wind speeds of Super Typhoon Lekima (2019) retrieved by Gaofen-3 SAR - He Fang; William Perrie; Gaofeng Fan; Zhengquan Li; Juzhen Cai; Yue He; Jingsong Yang; Tao Xie; Xuesong Zhu (Frontiers of Earth Science, 2022)

Processed potatoes intake and risk of type 2 diabetes: a systematic review and meta-analysis of nine prospective cohort studies - Wei Quan; Ye Jiao; Chaoyi Xue; Yong Li; Zhaojun Wang; Maomao Zeng; Fang Qin; Zhiyong He; Jie Chen (Critical Reviews in Food Science and Nutrition, 2022)

Stilbenoids from the roots of Stemona tuberosa - Hong-Mei Li; Tian-Tian He; Miao Zhang; Jia-Ning Liu; Xue Zhao; Jie Liu; Lei Fang (Natural Product Research, 2022)

A study of the phosphorylation proteomic skin characteristics of Tan sheep during the newborn and er-mao stages - Yonghong Chen; Dongqian He; Yachao Li; Fang Luo; Meng Zhang; Junkui Wang; Liyao Chen; Jinzhong Tao (Tropical Animal Health and Production, 2022)
In this experiment, in order to study the formation mechanism of the lamb fur of Tan sheep, skin samples were collected from Tan sheep at the newborn and er-mao stages. Then, the phosphorylated proteomes of the skin samples of Tan sheep at the two different stages were compared and analyzed using a TMT labeled quantitative phosphorylation proteomic technique. A total of 2806 phosphorylated proteins were identified, including 8184 phosphorylation sites. The results of this study’s quantitative analysis showed that when compared with the skin samples at the er-mao stage, the phosphorylation levels of 171 sites had been upregulated in the skin samples at newborn stage. Meanwhile, 125 sites had been downregulated at the same stage. As shown by the results of the functional enrichment analysis of the differentially phosphorylated proteins, they had been mainly enriched in the cysteine and methionine metabolism. In addition, the phosphorylation levels of KAP4.7 and KAP13.1 had also varied during the different skin stages. These results indicated that the cysteine metabolism pathways, as well as the phosphorylation modifications of the keratin associated proteins in the skin, played important roles in the formation of the er-mao stage fur of the Tan sheep. Therefore, the findings of this study provided a new angle for interpreting the formation mechanism of er-mao stage fur properties.

Exogenous IAA Alleviates Arsenic Toxicity to Rice and Reduces Arsenic Accumulation in Rice Grains - Yue He; Ting Zhang; Yu Sun; Xuejing Wang; Qingqing Cao; Zhigang Fang; Ming Chang; Qingsheng Cai; Laiqing Lou (Journal of Plant Growth Regulation, 2022)

Influence of climates and materials on the moisture buffering in office buildings: a comprehensive numerical study in China - Jinzhong Fang; Huibo Zhang; Peng Ren; Bao-Jie He; Mingfang Tang; Chi Feng (Environmental Science and Pollution Research, 2022)

Association between non-optimal temperature and hospitalizations for gout in Anqing, China: a time-series analysis - Yi-Sheng He; Gui-Hong Wang; Zheng-Dong Wu; Napoleon Bellua Sam; Yue Chen; Jin-Hui Tao; Xin-Yu Fang; Zhiwei Xu; Hai-Feng Pan (Environmental Science and Pollution Research, 2022)

Influence of epileptogenic region on brain structural changes in Rolandic epilepsy - Yin Xu; Qiang Xu; Qirui Zhang; Steven M. Stufflebeam; Fang Yang; Yan He; Zheng Hu; Yifei Weng; Junhao Xiao; Guangming Lu; Zhiqiang Zhang (Brain Imaging and Behavior, 2022)

Changes in the growth performance, antioxidant enzymes and stress resistance caused by dietary administration of synbiotic (fructooligosaccharide and probiotics) in juvenile Chinese Mitten Crab, Eriocheir sinensis - Jin-Juan Wan; Jian-lin Pan; Mei-Fang Shen; Hui Xue; Meng-lin Sun; Mei-Qin Zhang; Xi-He Zhu; Xing-kong Ma (Aquaculture International, 2022)

Depth‐dependent drivers of soil microbial necromass carbon across Tibetan alpine grasslands - Mei He; Kai Fang; Leiyi Chen; Xuehui Feng; Shuqi Qin; Dan Kou; Hongbo He; Chao Liang; Yuanhe Yang (Global Change Biology, 2022)
Microbial necromass carbon (C) has been considered an important contributor to persistent soil C pool. However, there still lacks large‐scale systematic observations on microbial necromass C in different soil layers, particularly for alpine ecosystems. Besides, it is still unclear whether the relative importance of biotic and abiotic variables such as plant C input and mineral properties in regulating microbial necromass C would change with soil depth. Based on the combination of large‐scale sampling along a ~2200 km transect across Tibetan alpine grasslands and biomarker analysis, together with a global data synthesis across grassland ecosystems, we observed a relatively low proportion of microbial‐derived C in Tibetan alpine grasslands compared to global grasslands (topsoil: 45.4% vs. 58.1%; subsoil: 41.7% vs. 53.7%). We also found that major determinants of microbial necromass C depended on soil depth. In topsoil, both plant C input and mineral protection exerted dominant effects on microbial necromass C. However, in subsoil, the physico‐chemical protection provided by soil clay particles, iron‐aluminum oxides, and exchangeable calcium dominantly facilitated the preservation of microbial necromass C. The differential drivers over microbial necromass C between soil depths should be considered in Earth system models for accurately forecasting soil C dynamics and its potential feedback to global warming.

Determination of the stable isotope discrimination factor of wild organisms: a case study of the red swamp crayfish in integrated rice–crayfish ( Procambarus clarkii ) culture without artificial diets - Mingdi He; Feng Liu; Fang Wang (Isotopes in Environmental and Health Studies, 2022)

The genomic history of southwestern Chinese populations demonstrated massive population migration and admixture among proto-Hmong–Mien speakers and incoming migrants - Yicheng Wang; Xing Zou; Mengge Wang; Didi Yuan; Li Yang; Yujie Zeng; Fang Cheng; Renkuan Tang; Guanglin He (Molecular Genetics and Genomics, 2022)

Above- and belowground biomass allocation and its regulation by plant density in six common grassland species in China - Yuanfeng Sun; Yupin Wang; Zhengbing Yan; Luoshu He; Suhui Ma; Yuhao Feng; Haojie Su; Guoping Chen; Yinping Feng; Chengjun Ji; Haihua Shen; Jingyun Fang (Journal of Plant Research, 2022)

Bioactive compounds derived from the marine-derived fungus MCCC3A00951 and their influenza neuraminidase inhibition activity in vitro and in silico - Shun-Zhi Liu; Feng-Ming He; Yan-lin Bin; Chu-Fang Li; Bao-Ying Xie; Xi-Xiang Tang; Ying-Kun Qiu (Natural Product Research, 2021)

Replacement of Astaxanthin With Lutein in Diets of Juvenile Litopenaeus vannamei: Effects on Growth Performance, Antioxidant Capacity, and Immune Response - HaoHang Fang; XuanShu He; HuLong Zeng; YongJian Liu; LiXia Tian; Jin Niu (Frontiers in Marine Science, 2021)
An 8-week feeding experiment was conducted to investigate whether diet supplementation of lutein could result in similar growth performance, antioxidant capacity, and immunity of Litopenaeus vannamei when compared to dietary astaxanthin. Juvenile L. vannamei (initial body weight: 0.64 ± 0.04 g) were fed with one of five isonitrogen and isolipids diets with/without lutein or astaxanthin [control group (C); the lutein (L) groups contained 0, 62.5, 75, 87.5 ppm lutein, respectively, the astaxanthin (A) group contained 50 ppm astaxanthin]. Results showed that dietary supplementation of lutein ranging from 62.5 to 75 ppm resulted in similar growth performance (WGR, SGR, FCR, and SR) of L. vannamei compared with the A group ( P > 0.05). Apart from that, no statistical difference was observed in antioxidant parameters (hemolymph T-AOC, hemolymph MDA, and RNA expression level of GSH-PX, CAT), anti-inflammatory ability (Relish, Rho, and HSP70) and apoptosis-related gene expression (Caspase3) among lutein treatments ranging from 62.5 to 87.5 ppm and the A group ( P > 0.05). These results indicate that a dose of 62.5–75 ppm of lutein was suitable in the diet of L. vannamei for substituting dietary astaxanthin.

Economic Evaluation of Water-Saving Irrigation Practices for Sustainable Sugarcane Production in Guangxi Province, China - Shan-Shan He; Yuan Zeng; Zhao-Xu Liang; Yan Jing; ShiYun Tang; Baoqing Zhang; Haifeng Yan; Song Li; Tinglin Xie; Fang Tan; Ming Li (Sugar Tech, 2021)

Recent advances in tissue stem cells - Xin Fu; Qiang He; Yu Tao; Mengdi Wang; Wei Wang; Yalong Wang; Qing Cissy Yu; Fang Zhang; Xiaoyu Zhang; Ye-Guang Chen; Dong Gao; Ping Hu; et al. (Science China Life Sciences, 2021)

Ellagic acid (EA), a tannin was isolated from Eucalyptus citriodora leaves and its anti-inflammatory activity - Yu Qiujian; Feng Zongcai; Huang Liping; He Jingwei; Zhou Zhongliu; Liu Fang (Medicinal Chemistry Research, 2021)

Memory regulation in feeding habit transformation to dead prey fish of Chinese perch (Siniperca chuatsi) - Linjie Shi; Jiao Li; Xu-Fang Liang; Shan He; Yaqi Dou; Jian Peng; Wenjing Cai; Hui Liang (Fish Physiology and Biochemistry, 2021)

Quantitative trait locus mapping and genomic selection of tobacco (Nicotiana tabacum L.) based on high-density genetic map - Zhijun Tong; Zhihui Xiu; Yao Ming; Dunhuang Fang; Xuejun Chen; Yafei Hu; Juhong Zhou; Weiming He; Fangchan Jiao; Chi Zhang; Shancen Zhao; Han Jin; et al. (Plant Biotechnology Reports, 2021)
Tobacco ( Nicotiana tabacum L.) is an economic crop and a model organism for studies of plant biology and genetics. As an allotetraploid plant generated from interspecific hybridization, tobacco has a massive genome (4.5 Gb). Recently, a genetic map with 45,081 single nucleotide polymorphism (SNP) markers was constructed using whole-genome sequencing data for a tobacco population including 274 individuals. This provides a basis for quantitative trait locus (QTL) mapping and genomic selection, which have been widely applied to other crops but have not been feasible in tobacco. Based on this high-density genetic map, we identified QTLs associated with important agronomic traits, chemical compounds in dry leaves, and hazardous substances in processed cigarettes. The LOD values for major QTLs were highest for agronomic traits, followed by chemical compounds and hazardous substances. In addition to the identification of molecular markers, we evaluated genomic selection models and found that BayesB had the highest prediction accuracy for the recombinant inbred line population. Our results offer new insights into the genetic mechanism underlying important traits, such as agronomic traits and quality-related chemical compounds in tobacco, and will be able to support the application of molecular breeding to tobacco.

Impact of an artificial chute cutoff on the river morphology and flow structure in Sipaikou area of the Upper Yellow River - Qiao Qiao; Chun-guang Li; He-fang Jing; Ling-xiao Huang; Cheng Yang (Journal of Mountain Science, 2021)

Role of NPY receptor 8 in regulating of food intake in Chinese perch (Siniperca chuatsi) - Yanpeng Zhang; Zhen Zhang; Xu-Fang Liang; Shan He; Jing Xu (Aquaculture International, 2021)

New cyclopentenoneacrylic acid derivatives from a marine-derived fungus Trichoderma atroviride H548 - Xi-Xiang Tang; Shun-Zhi Liu; Yu-Ying Sun; Feng-Ming He; Guang-Xin Xu; Mei-Juan Fang; Wu Zhen; Ying-Kun Qiu (Natural Product Research, 2021)

The new chimeric chiron genes evolved essential roles in zebrafish embryonic development by regulating NAD+ levels - Chengchi Fang; Xiaoni Gan; Chengjun Zhang; Shunping He (Science China Life Sciences, 2021)

A review on interplay between small RNAs and oxidative stress in cancer progression - Aparimita Das; Harsha Ganesan; Sushmitha Sriramulu; Francesco Marotta; N. R. Rajesh Kanna; Antara Banerjee; Fang He; Asim K. Duttaroy; Surajit Pathak (Molecular and Cellular Biochemistry, 2021)

Development and validation of gene-specific KASP markers for YrAS2388R conferring stripe rust resistance in wheat - Yanling Hu; Xuhui Huang; Fang Wang; Yu He; Lihua Feng; Bo Jiang; Ming Hao; Shunzong Ning; Zhongwei Yuan; Jiajie Wu; Lianquan Zhang; Bihua Wu; et al. (Euphytica, 2021)

Effect of Soil Properties and Aging Time on Oral and Inhalation Bioaccessibility of Copper Oxide Nanoparticles in Soils - Shiwei Li; Yanhua Qiu; Minghui Chang; Zongquan Sun; Fang He; Helian Li (Bulletin of Environmental Contamination and Toxicology, 2021)

Effects of Long-Term Exposure to Copper on the Keap1/Nrf2 Signaling Pathway and Msr-Related Redox Status in the Kidneys of Rats - Gaolong Zhong; Ying He; Fang Wan; Shaofeng Wu; Xuanxuan Jiang; Zhaoxin Tang; Lianmei Hu (Biological Trace Element Research, 2021)

AFAP1-AS1: a rising star among oncogenic long non-coding RNAs - Fang Xiong; Kunjie Zhu; Su Deng; Hongbin Huang; Liting Yang; Zhaojian Gong; Lei Shi; Yi He; Yanyan Tang; Qianjin Liao; Jianjun Yu; Xiaoling Li; et al. (Science China Life Sciences, 2021)

Lithospheric structures across the Qiman Tagh and western Qaidam Basin revealed by magnetotelluric data collected using a self-developed SEP system - Qingyun Di; Guoqiang Xue; Zhongxing Wang; Lanfang He; Renzhong Pei; Tianxin Zhang; Guangyou Fang (Science China Earth Sciences, 2021)

Metabolic responses of Chinese perch (Siniperca chuatsi) to different levels of dietary carbohydrate - Yanpeng Zhang; Xu-fang Liang; Shan He; Jie Wang; Ling Li; Zhen Zhang; Jiao Li; Xu Chen; Lu Li; Muhammad Shoaib Alam (Fish Physiology and Biochemistry, 2021)

Food-grade γ-aminobutyric acid production by immobilized glutamate decarboxylase from Lactobacillus plantarum in rice vinegar and monosodium glutamate system - Li-Li Yao; Jia-Ren Cao; Chang-Jiang Lyu; Fang-Fang Fan; Hong-Peng Wang; Hong-Wei Cao; Jun Huang; Le-He Mei (Biotechnology Letters, 2021)

Interactive effects of nutrient availability, fluctuating supply, and plant parasitism on the post-invasion success of Bidens pilosa - Fang-Lei Gao; Qiao-Sheng He; Ru-Qian Xie; Jia-Hui Hou; Chen-Lu Shi; Jun-Min Li; Fei-Hai Yu (Biological Invasions, 2021)

PEG‐modified subunit vaccine encoding dominant epitope to enhance immune response against spring viraemia of carp virus - Hui‐Xin Duan; Zhao Zhao; Ying‐Jie Jin; Zi‐Long Wang; Jie‐Fang Deng; Jie He; Bin Zhu (Journal of Fish Diseases, 2021)
Spring viraemia of carp (SVC) caused by spring viraemia of carp virus (SVCV) can infect almost all fish of cyprinids, which bring huge economic losses to aquaculture. Glycoprotein (G), as the most important antigenic determinant protein of SVCV, is widely considered as an effective method against SVCV. In our previous study, we found that G3 (131 aa) is the potential dominant antigen epitope that induces strong immune responses similar to G protein (510 aa). Here, in order to further improve the immune effect, we reported a subunit vaccine (PEG‐G3) constructed by PEG‐modified dominant epitope protein (G3). The results of serum antibody production, enzyme activities and immune‐related genes expression showed that PEG‐G3 induces significantly stronger immune protective responses against SVCV than G3. PEG modification significantly increased the serum antibody level of the vaccine, which increased significantly after immunization and reached the peak at 21 day post‐vaccination. T‐AOC and AKP activities in the lowest concentration group (5 μg) of PEG‐G3 were significantly higher than those in the highest concentration group (20 μg) of G3. In PEG‐G3 group, the expression of almost all genes increased at least 4 times compared with the control group. After 14‐day challenge, the RPS (relative percentage survival) of the highest concentration of PEG‐G3 group was 53.6%, while that of G3 group is 38.9%. Therefore, this work shows that PEG modification and dominant epitope screening may be effective methods to improve the immune protective effect of vaccines and to resist the infection of aquatic animal viral diseases.

High-resolution genome-wide association study and genomic prediction for disease resistance and cold tolerance in wheat - Yunlong Pang; Yuye Wu; Chunxia Liu; Wenhui Li; Paul St. Amand; Amy Bernardo; Danfeng Wang; Lei Dong; Xiufang Yuan; Huirui Zhang; Meng Zhao; Linzhi Li; et al. (Theoretical and Applied Genetics, 2021)

Lipidomic analyses reveal enhanced lipolysis in planthoppers feeding on resistant host plants - Xiaohong Zheng; Yeyun Xin; Yaxin Peng; Junhan Shan; Ning Zhang; Di Wu; Jianping Guo; Jin Huang; Wei Guan; Shaojie Shi; Cong Zhou; Rongzhi Chen; et al. (Science China Life Sciences, 2021)

Adaptation of AMPK-mTOR-signal pathways and lipid metabolism in response to low- and high-level rapeseed meal diet in Chinese perch (Siniperca chuatsi) - Jiao Li; Xu-Fang Liang; Muhammad Shoaib Alam; Haocan Luo; Yanpeng Zhang; Binbin Peng; Qianqian Xiao; Zhilu Zhang; Liwei Liu; Shan He (Journal of Comparative Physiology B, 2021)

Smad3 gene C-terminal phosphorylation site mutation exacerbates CCl4-induced hepatic fibrogenesis by promoting pSmad2L/C-mediated signaling transduction - Juan Yang; Yongfang Gong; Wenjing Xu; Lili Li; Zhenghao Shi; Qin Wang; Yinghao He; Chong Zhang; Chenchen Luo; Zhirui Fang; Yan Yang (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Serotonin 2A receptor function and depression-like behavior in rats model of hypothyroidism - Zhicheng Jin; Jianer Ling; Jing Yu; Mengzi He; Pingping Ni; Fang Zhang; Yizhen Wang (Experimental Brain Research, 2021)

A comparison study of applying natural iron minerals and zero-valent metals as Fenton-like catalysts for the removal of imidacloprid - Siwan Liu; Wenwei Yu; Huang Cai; Faying Lai; Hansun Fang; Huajun Huang; Jinbao He (Environmental Science and Pollution Research, 2021)

Abnormal white matter microstructure along the thalamus fiber pathways in women with primary dysmenorrhea - Juan He; Wanghuan Dun; Fang Han; Ke Wang; Jing Yang; Shaohui Ma; Ming Zhang; Jixin Liu; Hongjuan Liu (Brain Imaging and Behavior, 2021)

Variation in Micro-Pores during Dynamic Consolidation and Compression of Soft Marine Soil - Chen-Xiang Dai; Qiong-Fang Zhang; Shao-Heng He; An Zhang; Hua-Feng Shan; Tang-Dai Xia (Journal of Marine Science and Engineering, 2021)
In this study, to explore the microstructure deformation mechanism of marine soft marine soil under cyclic loading, we analyzed the dynamic properties of soft marine soil under cyclic loading via dynamic consolidation compression testing. Then, using Image-Pro Plus (IPP) 6.0 image analysis software, and according to the dynamic consolidation compression test results and the images from a scanning electron microscope (SEM), we determined the weakening effect of soft soils under different consolidation confining pressures, different cyclic stress ratios, and different over-consolidation ratios. After dynamic consolidation and compression, the pore structure of undisturbed soft marine soil tends to compact, the degree of soil particle fragmentation intensifies, small pores increase, large pores decrease, the pores become more regular, and the distribution of pores is directional. Subsequently, for undisturbed soft marine soil, the higher the consolidated confining pressure, cyclic dynamic stress ratio, and over-consolidation ratio, the greater the damage to the pore structure, and the more obvious the structural weakening effect exhibited under cyclic loading.

A Hu sheep genome with the first ovine Y chromosome reveal introgression history after sheep domestication - Ran Li; Peng Yang; Ming Li; Wenwen Fang; Xiangpeng Yue; Hojjat Asadollahpour Nanaei; Shangquan Gan; Duo Du; Yudong Cai; Xuelei Dai; Qimeng Yang; Chunna Cao; et al. (Science China Life Sciences, 2021)

Regulatory mechanism of GA3 on tuber growth by DELLA-dependent pathway in yam (Dioscorea opposita) - Yunyi Zhou; Yuting Li; Mingxia Gong; Fang Qin; Dong Xiao; Jie Zhan; Aiqin Wang; Longfei He (Plant Molecular Biology, 2021)

HDAC3 Downregulation Improves Cerebral Ischemic Injury via Regulation of the SDC1-Dependent JAK1/STAT3 Signaling Pathway Through miR-19a Upregulation - Hua Fang; Hua-Feng Li; Ming-Hai He; Miao Yang; Jian-Ping Zhang (Molecular Neurobiology, 2021)

Association Between Selenium Level in Blood and Glycolipid Metabolism in Residents of Enshi Prefecture, China - Haiqin Fang; Xiaohong He; Yingyu Wu; Siqiang Chen; Mingyuan Zhang; Feng Pan; Jiao Huang; Aidong Liu (Biological Trace Element Research, 2021)

The crustal nature of the northern Mozambique Ridge, Southwest Indian Ocean - Nelta David Matsinhe; Yong Tang; Chun-Feng Li; Jiabiao Li; Estevão Stefane Mahanjane; He Li; Yinxia Fang (Acta Oceanologica Sinica, 2021)

The Sediment Selectivity of Perinereis aibuhitensis Larvae: Active or Passive? - Jinghui Fang; Wei He; Shan Meng; Zengjie Jiang; Jianguang Fang; Yuze Mao; Bo Liang (Frontiers in Marine Science, 2021)
The selectivity of Perinereis aibuhitensis larvae on different sediment types was studied using an experimental behavioral device in the lab. There were six types of sediment with different organic matter content: 2.19, 2.30, 2.86, 3.25, 3.51, and 5.52%. The results indicated significant differences in the six treatments’ organic matter content ( p < 0.05). When the P. aibuhitensis larvae initially attached to the sediment, the larvae’s density showed no significant difference among the six treatments. The density of larvae decreased gradually during the experimental period. It increased with the increasing organic matter content in sediment at every sampling time, but there was no significant difference ( p > 0.05). The larvae’s specific growth rate in the first month was significantly higher than those in the second and third months ( p < 0.05). The mortality showed no significance at different sediments in equal sampling times, but the mortality was lower in high organic matter content sediments. This study showed that the P. aibuhitensis larvae did not make an active selection; random selection happened when initially attached to the sediment with different organic matter contents. Higher organic matter content in the sediment was more conducive to larvae survival, and the organic matter content is the limitation factor on the mortality and the density. The different densities in the natural habitat of P. aibuhitensis might occur due to the passive selection by the environment.

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Exogenous Salicylic Acid Alleviates the Antimony (Sb) Toxicity in Rice (Oryza sativa L.) Seedlings - Wen-Tao Luo; Li He; Fang Li; Jiao-Kun Li (Journal of Plant Growth Regulation, 2021)

Petroleum contamination significantly changes soil microbial communities in three oilfield locations in Delta State, Nigeria - Macdonald Ogorm Mafiana; Xiao-Hu Kang; Yan Leng; Li-Fang He; Shi-Weng Li (Environmental Science and Pollution Research, 2021)

Assessment of the Tidal Current Energy Resources and the Hydrodynamic Impacts of Energy Extraction at the PuHu Channel in Zhoushan Archipelago, China - He Wu; Huaming Yu; Yizhou Fang; Qingwei Zhou; Fengxuan Zhuo; Ryan M. Kelly (Journal of Ocean University of China, 2021)

Correction to: Insights on Droplet Digital PCR–Based Cellular Kinetics and Biodistribution Assay Support for CAR-T Cell Therapy - Hiroshi Sugimoto; Susan Chen; Jean-Pierre Minembe; Johara Chouitar; Xingyue He; Haiqing Wang; Xiaodong Fang; Mark G. Qian (The AAPS Journal, 2021)

Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020 - Encheng Sun; Zhenjiang Zhang; Zilong Wang; Xijun He; Xianfeng Zhang; Lulu Wang; Wenqing Wang; Lianyu Huang; Fei Xi; Haoyue Huangfu; Ghebremedhin Tsegay; Hong Huo; et al. (Science China Life Sciences, 2021)

Molecular model construction of Danhou lignite and study on adsorption of CH4 by oxygen functional groups - Hongqing Zhu; Yujia Huo; Xin He; Wei Wang; Shuhao Fang; Yilong Zhang (Environmental Science and Pollution Research, 2021)

Marinisubtilis pacificus gen. nov., sp. nov., a Member of the Family Microbacteriaceae Isolated From a Deep-Sea Seamount - Fang Qin; Wen-Xuan He; De-Chao Zhang (Current Microbiology, 2021)

Comparison of picoeukaryote community structures and their environmental relationships between summer and autumn in the southern Chukchi Sea - Fang Zhang; Jianfeng He; Haiyan Jin; Qiang Hao; Zhongyong Gao; Heng Sun (Extremophiles, 2021)

Lithium alleviated spinal cord injury (SCI)-induced apoptosis and inflammation in rats via BDNF-AS/miR-9-5p axis - Fang Wang; Sue Chang; Jie Li; Dong Wang; Haopeng Li; Xijing He (Cell and Tissue Research, 2021)

Water and nutrient relations of mistletoes at the drought limit of their hosting evergreen oaks in the semiarid upper Yangtze region, SW China - Xiao-Fang He; Song-Wei Wang; Christian Körner; Yang Yang (Trees, 2021)

Correction to: Icariside II promotes the differentiation of human amniotic mesenchymal stem cells into dopaminergic neuron-like cells - Wei Kuang; Tao Liu; Fang He; Limei Yu; Qian Wang; Changyin Yu (In Vitro Cellular & Developmental Biology - Animal, 2021)

Icariside II promotes the differentiation of human amniotic mesenchymal stem cells into dopaminergic neuron-like cells - Wei Kuang; Tao Liu; Fang He; Limei Yu; Qian Wang; Changyin Yu (In Vitro Cellular & Developmental Biology - Animal, 2021)

Impacts of native vegetation on the hydraulic properties of the concentrated flows in bank gullies - Zheng-an Su; Zhou-yao He; Tao Zhou; Jun-jie Wang; Xiao-yi Wang; Li-juan Wang; Hai-dong Fang; Liang-tao Shi; Yi-han Liu; Zuo Wu (Journal of Mountain Science, 2021)

Correction to: Elevation-specific responses of phenology in evergreen oaks from their low-dry to their extreme high-cold range limits in the SE Himalaya - Song-Wei Wang; Xiao-Fang He; Jian-Guo Chen; Hang Sun; Christian Körner; Yang Yang (Alpine Botany, 2021)

Elevation-specific responses of phenology in evergreen oaks from their low-dry to their extreme high-cold range limits in the SE Himalaya - Song-Wei Wang; Xiao-Fang He; Jian-Guo Chen; Hang Sun; Christian Körner; Yang Yang (Alpine Botany, 2021)

Comparisons of OCO-2 satellite derived XCO2 with in situ and modeled data over global ocean - Siqi Zhang; Yan Bai; Xianqiang He; Haiqing Huang; Qiangkun Zhu; Fang Gong (Acta Oceanologica Sinica, 2021)

Sesquiterpenoids from the roots and rhizomes of Valeriana amurensis and their effects on NGF-induced neurite outgrowth in PC12 cells - Fa-Wu Dong; Fang Li; Jia-Jia Ren; Cheng-Mei Zhao; Hong-Li Diao; Bao-Jing Li; Yan-Ping Li; Jiang-Miao Hu; Hong-Ping He (Natural Product Research, 2021)

Insights on Droplet Digital PCR–Based Cellular Kinetics and Biodistribution Assay Support for CAR-T Cell Therapy - Hiroshi Sugimoto; Susan Chen; Jean-Pierre Minembe; Johara Chouitar; Xingyue He; Haiqing Wang; Xiaodong Fang; Mark G. Qian (The AAPS Journal, 2021)
Characterizing in vivo cellular kinetics and biodistribution of chimeric antigen receptor T (CAR-T) cells is critical for toxicity assessment, nonclinical and clinical efficacy studies. To date, the standardized assay to characterize CAR-T cell distribution, expansion, contraction, and persistence profiles is not readily available. To overcome this limitation and increase comparability among studies, we have established a universal protocol for analysis. We established a duplexing ddPCR protocol for the CAR-T transgene and reference gene to normalize the genomic DNA input prepared from mouse blood and tissues. The high-throughput gDNA extraction method enabled highly reproducible gDNA extraction while eliminating labor-intensive steps. The investigational CAR-T cells were intravenously injected into immunodeficient mice bearing human colorectal cancer xenografts. The blood and tissue samples were collected to measure the cellular kinetics by ddPCR and flow cytometry. The standard curves were linear throughout the calibration range with acceptable intra- and inter-day precision and accuracy. The gDNA recovery study performed by spiking in the exo-gene plasmid DNA or CAR-T cells revealed that the recovery ranged from 60 to 100% in blood and tissue homogenates. The use of both units of copy/μg gDNA and copy/μL blood met the current regulatory requirement and allowed for a systematic understanding of CAR-T cell expansion and a direct comparison with the flow cytometry data. A standardized ddPCR assay, including automated gDNA extraction procedures, has been established for evaluating cellular kinetics and biodistribution in CAR-T cell therapies.

SNI and CFA induce similar changes in TRPV1 and P2X3 expressions in the acute phase but not in the chronic phase of pain - Junfan Fang; Junying Du; Xuaner Xiang; Xiaomei Shao; Xiaofeng He; Yongliang Jiang; Boyi Liu; Yi Liang; Jianqiao Fang (Experimental Brain Research, 2021)

Antimonate removal by diatomite modified with Fe-Mn oxides: application and mechanism study - Qiu-Yi Dong; Yu-Chun Fang; Bin Tan; Aura Ontiveros-Valencia; Ang Li; He-Ping Zhao (Environmental Science and Pollution Research, 2021)

Oceanomicrobium pacificus gen. nov., sp. nov., a member of the family Rhodobacteraceae isolated from seawater of tropical western Pacific - Dadong Dai; Yangjie Li; Wenxuan He; Fang Qin; Jinshui Zheng; Ming Sun; Dechao Zhang (Antonie van Leeuwenhoek, 2021)

Analyzing the spatial network structure of agricultural greenhouse gases in China - Yanqiu He; Xiang Lan; Zuoang Zhou; Fang Wang (Environmental Science and Pollution Research, 2021)

Abscisic acid modulates differential physiological and biochemical responses of roots, stems, and leaves in mung bean seedlings to cadmium stress - Yan Leng; Yi Li; Yan-Hua Ma; Li-Fang He; Shi-Weng Li (Environmental Science and Pollution Research, 2021)

The participation of basolateral amygdala in the efficacy of acupuncture with deqi treating for functional dyspepsia - Ruirui Sun; Zhaoxuan He; Peihong Ma; Shuai Yin; Tao Yin; Xiaoyan Liu; Jin Lu; Yuzhu Qu; Tingting Zhang; Liuyang Huang; Xueling Suo; Du Lei; et al. (Brain Imaging and Behavior, 2021)

Anaerobic biodegradation of phenanthrene by a newly isolated nitrate‐dependent Achromobacter denitrificans strain PheN1 and exploration of the biotransformation processes by metabolite and genome analyses - Zuotao Zhang; Jiao Sun; Haijiao Guo; Chongyang Wang; Tingting Fang; Matthew J. Rogers; Jianzhong He; Hui Wang (Environmental Microbiology, 2021)
Summary Polycyclic aromatic hydrocarbons (PAHs) are widespread and harmful contaminants and are more persistent under anaerobic conditions. The bioremediation of PAHs in anaerobic zones has been enhanced by treating the contamination with nitrate, which is thermodynamically favourable, cost‐effective, and highly soluble. However, anaerobic PAHs biotransformation processes that employ nitrate as an electron acceptor have not been fully explored. In this study, we investigated the anaerobic biotransformation of PAHs by strain PheN1, a newly isolated phenanthrene‐degrading denitrifier, using phenanthrene as a model compound. PheN1 is phylogenetically closely related to Achromobacter denitrificans and reduces nitrate to nitrite (not N 2 ) during the anaerobic phenanthrene degradation process. Phenanthrene biotransformation processes were detected using gas chromatography–mass spectrometry and were further examined by reverse transcription‐quantitative PCR and genome analyses. Carboxylation and methylation were both found to be the initial steps in the phenanthrene degradation process. Downstream biotransformation processed benzene compounds and cyclohexane derivatives. This study describes the isolation of an anaerobic phenanthrene‐degrading bacterium along with the pure‐culture evidence of phenanthrene biotransformation processes with nitrate as an electron acceptor. The findings in this study can improve our understanding of anaerobic PAHs biodegradation processes and guide PAHs bioremediation by adding nitrate to anaerobic environments.

Extracellular enzyme stoichiometry reveals the carbon and phosphorus limitations of microbial metabolisms in the rhizosphere and bulk soils in alpine ecosystems - Yongxing Cui; Haijian Bing; Linchuan Fang; Mao Jiang; Guoting Shen; Jialuo Yu; Xia Wang; He Zhu; Yanhong Wu; Xingchang Zhang (Plant and Soil, 2021)

Identification of 5S and 45S rDNA sites in Chrysanthemum species by using oligonucleotide fluorescence in situ hybridization (Oligo-FISH) - Jun He; Sisi Lin; Zhongyu Yu; Aiping Song; Zhiyong Guan; Weimin Fang; Sumei Chen; Fei Zhang; Jiafu Jiang; Fadi Chen; Haibin Wang (Molecular Biology Reports, 2021)

Nrn1 Overexpression Attenuates Retinal Ganglion Cell Apoptosis, Promotes Axonal Regeneration, and Improves Visual Function Following Optic Nerve Crush in Rats - Tingting Huang; He Li; Shoumei Zhang; Fang Liu; Dong Wang; Jiajun Xu (Journal of Molecular Neuroscience, 2021)

Sources and ecological risk assessment of the seawater potentially toxic elements in Yangtze River Estuary during 2009–2018 - Yang Hu; Ning He; Mingxuan Wu; Pengling Wu; Peimin He; Ying Yang; Qinyi Wang; Maoqiu Wang; Shubo Fang (Environmental Monitoring and Assessment, 2021)

Isolation and characterization of two new chroman-4-ones from the endophytic fungus Penicillium chrysogenum obtained from Eucommia ulmoides Oliver - Sheng-Yue Liu; Li-Zhi Wang; Yue-Fei Wang; Lin Li; Guo-Ying Han; Bing-Yang Zhang; Ying Guo; Yong-Zhi He; Shi-Ming Fang; Han Zhang (Natural Product Research, 2020)

Does Soil Pore Water Salinity or Elevation Influence Vegetation Spatial Patterns along Coasts? A Case Study of Restored Coastal Wetlands in Nanhui, Shanghai - Mingxuan Wu; Yang Hu; Pengling Wu; Peimin He; Ning He; Bolun Zhang; Shengle Zhang; Shubo Fang (Wetlands, 2020)

Treatment of CML-transformed B Cell Acute Lymphoblastic Leukemia (B-ALL) in Adults with Anti-CD19 Chimeric Antigen Receptor T Cell (CAR T) Therapy - Fang Liu; Sha Sha; Gina Ma; Yi Su; Yisong Xiong; Guangcui He; Yecheng Li; William M. Hanes; William Tse (Stem Cell Reviews and Reports, 2020)

Electroacupuncture alleviates diabetic neuropathic pain in rats by suppressing P2X3 receptor expression in dorsal root ganglia - Xueyu Fei; Xiaofen He; Zhaoxia Tai; Hanzhi Wang; Siying Qu; Luhang Chen; Qunqi Hu; Jianqiao Fang; Yongliang Jiang (Purinergic Signalling, 2020)
Diabetic neuropathic pain (DNP) is a troublesome diabetes complication all over the world. P2X3 receptor (P2X3R), a purinergic receptor from dorsal root ganglion (DRG), has important roles in neuropathic pain pathology and nociceptive sensations. Here, we investigated the involvement of DRG P2X3R and the effect of 2 Hz electroacupuncture (EA) on DNP. We monitored the rats’ body weight, fasting blood glucose level, paw withdrawal thresholds, and paw withdrawal latency, and evaluated P2X3R expression in DRG. We found that P2X3R expression is upregulated on DNP, while 2 Hz EA is analgesic against DNP and suppresses P2X3R expression in DRG. To evaluate P2X3R involvement in pain modulation, we then treated the animals with A317491, a P2X3R specific antagonist, or α β-me ATP, a P2X3R agonist. We found that A317491 alleviates hyperalgesia, while α β-me ATP blocks EA’s analgesic effects. Our findings indicated that 2 Hz EA alleviates DNP, possibly by suppressing P2X3R upregulation in DRG.

Spatial correlation of China’s agricultural greenhouse gas emissions: a technology spillover perspective - Yanqiu He; Xueying Cheng; Fang Wang; Ya Cheng (Natural Hazards, 2020)

Etv5 safeguards trophoblast stem cells differentiation from mouse EPSCs by regulating fibroblast growth factor receptor 2 - Kui Zhu; Yuan Liu; Chen Fan; Mengyao Zhang; Hongxia Cao; Xin He; Na Li; Dianfeng Chu; Fang Li; Min Zou; Jinlian Hua; Huayan Wang; et al. (Molecular Biology Reports, 2020)

The Responses of Maize Yield and Water Use to Growth Stage-Based Irrigation on the Loess Plateau in China - Ning Jin; Jianqiang He; Quanxiao Fang; Chao Chen; Qingfu Ren; Liang He; Ning Yao; Libing Song; Qiang Yu (International Journal of Plant Production, 2020)

Valine acts as a nutritional signal in brain to activate TORC1 and attenuate postprandial ammonia-N excretion in Chinese perch (Siniperca chuatsi) - Jie Wang; Xu-Fang Liang; Shan He; Yan-Peng Zhang; Jiao Li; Kang Huang; Lin-Jie Shi; Ping Ren (Fish Physiology and Biochemistry, 2020)

Competitive Adsorption and Mobility of Propiconazole and Difenoconazole on Five Different Soils - Feiyan Wang; Duantao Cao; Lihong Shi; Shuhong He; Xin Li; Hua Fang; Yunlong Yu (Bulletin of Environmental Contamination and Toxicology, 2020)

Colonization by dark septate endophytes improves the growth of Hedysarum scoparium under multiple inoculum levels - Yiling Zuo; Fang Su; Xueli He; Min Li (Symbiosis, 2020)

Greater promotion of DNRA rates and nrfA gene transcriptional activity by straw incorporation in alkaline than in acidic paddy soils - Ren Bai; Yun-Ting Fang; Liu-Ying Mo; Ju-Pei Shen; Lin-Lin Song; Ya-Qi Wang; Li-Mei Zhang; Ji-Zheng He (Soil Ecology Letters, 2020)

The Developmental Plasticity of Boldness and Aggressiveness in Juvenile and Adult Swimming Crab (Portunus trituberculatus) - Qihang Liang; Xianpeng Su; Fang Wang; Baishan Zhu; Mingdi He (Frontiers in Marine Science, 2020)
Boldness and aggressiveness are crucial behavioral traits in the field of animal personality, and both have important ecological and evolutionary significance. As swimming crabs ( Portunus trituberculatus ) are aggressive, their production is affected; thus, it is important to study their behavior. To assess the relationship between boldness and aggressiveness of male P. trituberculatus and the differences between their different life stages, we determined the individual differences in these two traits in juvenile and adult crabs under laboratory conditions. Based on the k-means cluster analysis, boldness of crabs is classified according to their rush to adventure, and aggressiveness of crabs is classified according to their aggressive behavior toward conspecifics. The results show that the personality classification of juvenile and adult crabs was consistent. Boldness was divided into three levels: bold, middle, and shy. Aggressiveness was divided into two levels: aggressiveness and non-aggressiveness. The personality of juveniles and adults P. trituberculatus males was significantly different; juveniles presented higher aggressiveness and lower boldness than adults. Additionally, a significant positive correlation between boldness and aggressiveness of adult crabs was verified ( P = 0.001, ρ = 0.271). However, this correlation in juvenile crabs was not significant ( P = 0.702, ρ = 0.042). These preliminary results indicate that the personality of P. trituberculatus males has developmental plasticity and adults have the boldness-aggressiveness behavioral syndrome.

Activin A affects feeding by promoting the inner diameter and muscle development of the pharynx and oesophagus in zebrafish ( Danio rerio ) larvae - Shulin Tang; Xu‐Fang Liang; Shan He; Muhammad Shoaib Alam; Haocan Luo; Yulan Kuang (Journal of Fish Biology, 2020)
Activin A belongs to the superfamily of transforming growth factor‐β and plays an important role in hormone regulation and tissue development. However, few research studies have been conducted on the effect of activin A on feeding organs in fish. In this study, the zebrafish ( Danio rerio ) larvae were treated with 1 ng ml –1 activin A for 8 days continuously. The haematoxylin and eosin (H&E) staining section results revealed that the transverse inner diameter of the pharynx and oesophagus significantly increased on the third and eighth days after treatment compared with the control group ( P 2 compared to the control group ( P in situ hybridization results also showed that the expression of skeletal muscle‐specific genes ( myog and myod ) was significantly increased in pharyngeal muscle on the eighth day. Furthermore, the qRT‐PCR results showed the expression of gh gene was significantly increased on the eighth day ( P Artemia ) than in the control group on the eighth day. In conclusion, activin A could affect feeding by promoting the inner diameter and muscle development of the pharynx and oesophagus in zebrafish larvae. This study is the first to report that the development of the pharynx and oesophagus can directly affect food intake in fish larvae, which provides a theoretical basis for the study of food intake of fish at an early stage.

Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells - Yiran Sun; Libo He; Taoyu Wang; Wan Hua; Huan Qin; Jingjin Wang; Li Wang; Wanqin Gu; Tingting Li; Na Li; Xinanbei Liu; Fang Chen; et al. (Molecular Neurobiology, 2020)

Improving the thermostability of a GH97 dextran glucosidase by rational design - Xiaomin Zhang; Feiyun Chen; Chao He; Wei Fang; Zemin Fang; Xuecheng Zhang; Xiaotang Wang; Yazhong Xiao (Biotechnology Letters, 2020)

Chemical constituents from Glehnia littoralis and their chemotaxonomic significance - Shouwen Zhang; Fang Cheng; Li Yang; Jinxiang Zeng; Fengyu Han; Xiuling Yu; Yuye Zhu; Guoyue Zhong; Junwei He (Natural Product Research, 2020)

Highly sensitive serological approaches for Pepino mosaic virus detection - Wan-qin He; Jia-yu Wu; Yi-yi Ren; Xue-ping Zhou; Song-bai Zhang; Ya-juan Qian; Fang-fang Li; Jian-xiang Wu (Journal of Zhejiang University-SCIENCE B, 2020)

Technological strategy and mobility of Middle Holocene hunter-gatherers in the high-altitude Qinghai-Tibetan Plateau: a case study from Tshem gzhung kha thog - Fang Han; Yuanhong He; Wei Du; Linghai Cai; Hongliang Lu (Archaeological and Anthropological Sciences, 2020)

Design, Characterization, and Application of a pH-Triggered In Situ Gel for Ocular Delivery of Vinpocetine - Qun Ma; Rui Luo; Huimin Zhang; Manman Dai; Luyu Bai; Qingsong Fei; Fang Lei; Ning He (AAPS PharmSciTech, 2020)

Correction to: Long non-coding RNA H19 promotes osteogenic differentiation of renal interstitial fibroblasts through Wnt-β-catenin pathway - Zewu Zhu; Yu Cui; Fang Huang; Huimin Zeng; Weiping Xia; Feng Zeng; Cheng He; Jinbo Chen; Zhiyong Chen; Hequn Chen; Yang Li (Molecular and Cellular Biochemistry, 2020)

Intranasal Delivery of lincRNA-Cox2 siRNA Loaded Extracellular Vesicles Decreases Lipopolysaccharide-Induced Microglial Proliferation in Mice - Ke Liao; Fang Niu; Raghubendra Singh Dagur; Mengfan He; Changhai Tian; Guoku Hu (Journal of Neuroimmune Pharmacology, 2020)

Enhanced bioremediation of diesel range hydrocarbons in soil using biochar made from organic wastes - Sadia Aziz; Muhammad Ishtiaq Ali; Uzma Farooq; Asif Jamal; Fang-Jing Liu; Huan He; Hongguang Guo; Michael Urynowicz; Zaixing Huang (Environmental Monitoring and Assessment, 2020)

Arrival picking method for microseismic phases based on curve fitting - Zhi-Chao Yu; Jing Yu; Fang-Fang Feng; Yu-Yang Tan; Gui-Ting Hou; Chuan He (Applied Geophysics, 2020)

Revisiting the Concentration Observations and Source Apportionment of Atmospheric Ammonia - Yuepeng Pan; Mengna Gu; Yuexin He; Dianming Wu; Chunyan Liu; Linlin Song; Shili Tian; Xuemei Lü; Yang Sun; Tao Song; Wendell W. Walters; Xuejun Liu; et al. (Advances in Atmospheric Sciences, 2020)

3D printing of food: pretreatment and post-treatment of materials - Chang He; Min Zhang; Zhongxiang Fang (Critical Reviews in Food Science and Nutrition, 2020)

Identification and evaluation of tobacco cytoplasmic male sterile line Nta(gla)S K326 generated from asymmetric protoplast fusion of Nicotiana glauca and N. tabacum followed by backcrossing with N. tabacum K326 - Xue-Jun Chen; Zhi-Jun Tong; Bing-Guang Xiao; Yong-Ping Li; Fang-Chan Jiao; Yong Li; Tao Pang; Dun-Huang Fang; Xing-Fu Wu; Yi-Han Zhang; He Xie; Ge Bai; et al. (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

All-Trans Retinoic Acid Exerts Neuroprotective Effects in Amyotrophic Lateral Sclerosis-Like Tg (SOD1*G93A)1Gur Mice - Yu Zhu; Yue Liu; Fang Yang; Wenzhi Chen; Jianxian Jiang; Pei He; Shishi Jiang; Menhua Li; Renshi Xu (Molecular Neurobiology, 2020)

Association between chronic kidney disease and Alzheimer’s disease: an update - Chun-Yun Zhang; Fang-Fang He; Hua Su; Chun Zhang; Xian-Fang Meng (Metabolic Brain Disease, 2020)

Comparative Pharmacokinetics of Nimodipine in Rat Plasma and Tissues Following Intraocular, Intragastric, and Intravenous Administration - Fang Li; Qingsong Fei; Dan Mao; Qiaoyun Si; Manman Dai; Qun Ma; Huimin Zhang; Luyu Bai; Ning He (AAPS PharmSciTech, 2020)

Long non-coding RNA H19 promotes osteogenic differentiation of renal interstitial fibroblasts through Wnt-β-catenin pathway - Zewu Zhu; Yu Cui; Fang Huang; Huimin Zeng; Weiping Xia; Feng Zeng; Cheng He; Jinbo Chen; Zhiyong Chen; Hequn Chen; Yang Li (Molecular and Cellular Biochemistry, 2020)

An experimental study of the isolation performance of trenches on ground-borne vibration from underground tunnels - Yang Wenbo; Shang Yingchao; Liu Dexiong; Zou Tao; Yan Qixiang; Fang Yong; He Chuan (Earthquake Engineering and Engineering Vibration, 2020)

Production, Identification and Characterization of Erianthus rockii × Narenga porphyrocoma Intergeneric Hybrids as a New Germplasm for Sugarcane Breeding and Genetic Research - Hailong Chang; Qinnan Wang; Yongsheng Qiu; Yuanxia Qin; Xueting Li; Qingdan Wu; Weiping He; Yuqiang Guo; Wei Zhang; Junlv Chen; Na Fang (Sugar Tech, 2020)

Lactobacillus rhamnosus GG and Bifidobacterium bifidum TMC3115 Can Affect Development of Hippocampal Neurons Cultured In Vitro in a Strain-Dependent Manner - Ruyue Cheng; Tong Xu; Yujie Zhang; Feng Wang; Linsen Zhao; Yugang Jiang; Fang He (Probiotics and Antimicrobial Proteins, 2020)

Reversal of Social Recognition Deficit in Adult Mice with MECP2 Duplication via Normalization of MeCP2 in the Medial Prefrontal Cortex - Bin Yu; Bo Yuan; Jian-Kun Dai; Tian-lin Cheng; Sheng-Nan Xia; Ling-Jie He; Yi-Ting Yuan; Yue-Fang Zhang; Hua-Tai Xu; Fu-Qiang Xu; Zhi-Feng Liang; Zi-Long Qiu (Neuroscience Bulletin, 2020)

Input and output of cadmium (Cd) for paddy soil in central south China: fluxes, mass balance, and model predictions - Yun-He Xie; Jian Zhu; Sai-Hua Liu; Shu-Fang Pan; Xiong-Hui Ji (Environmental Science and Pollution Research, 2020)

ENSO’s impacts on the tropical Indian and Atlantic Oceans via tropical atmospheric processes: observations versus CMIP5 simulations - Shan He; Jin-Yi Yu; Song Yang; Shih-Wei Fang (Climate Dynamics, 2020)
This study compares the impacts of the El Niño–Southern Oscillation (ENSO) on sea surface temperatures (SSTs) in the tropical North Atlantic Ocean and the tropical Indian Ocean during 1958–2004. It is found that the tropical atmospheric processes mediating the ENSO impacts are different between the two oceans for two reasons. First, the ENSO-induced anomalous Walker circulation is more extensive over the Atlantic than over the Indian Ocean. As a result, the atmospheric bridge (AB) mechanism is the major contributor to the differences in ENSO teleconnections between the two oceans. Secondly, SSTs in the tropical North Atlantic are under a greater control of the atmospheric thermal forcing than those in the tropical Indian Ocean. Due to these different controls, the tropospheric temperature (TT) mechanism also contributes to the different ENSO teleconnections. When compared with the observations, the mean of thirty-seven models from the Coupled Model Intercomparison Project Phase 5 overestimates the ENSO-induced SST response in the tropical Indian Ocean but underestimates the response in the tropical North Atlantic. The overestimation is brought about by a westward extension of ENSO SST anomalies in the models, which causes the AB mechanism to produce an overly strong impact on Indian Ocean SSTs. On the other hand, the underestimation is caused by a weaker-than-observed sensitivity in the simulated Atlantic SSTs to the thermal forcing produced by the TT mechanism.

Simulation of the landform change process on a purple soil slope due to tillage erosion and water erosion using UAV technology - Chao Yang; Zheng-an Su; Jian-rong Fan; Hai-dong Fang; Liang-tao Shi; Jian-hui Zhang; Zhou-yao He; Tao Zhou; Xiao-yi Wang (Journal of Mountain Science, 2020)

Doxorubicin sensitizes cancer cells to Smac mimetic via synergistic activation of the CYLD/RIPK1/FADD/caspase-8-dependent apoptosis - Chengkui Yang; Qiao Ran; Yifei Zhou; Shan Liu; Cong Zhao; Xiaoliang Yu; Fang Zhu; Yuting Ji; Qian Du; Tao Yang; Wei Zhang; Sudan He (Apoptosis, 2020)

Background Characteristics of Atmospheric CO2 and the Potential Source Regions in the Pearl River Delta Region of China - Boru Mai; Xuejiao Deng; Fang Zhang; Hao He; Tian Luan; Fei Li; Xia Liu (Advances in Atmospheric Sciences, 2020)

Detection of serum IgM and IgG for COVID-19 diagnosis - Ling Zhong; Junlan Chuan; Bo Gong; Ping Shuai; Yu Zhou; Yi Zhang; Zhilin Jiang; Dingding Zhang; Xiaoqi Liu; Shi Ma; Yi Huang; He Lin; et al. (Science China Life Sciences, 2020)

A seven-gene-deleted African swine fever virus is safe and effective as a live attenuated vaccine in pigs - Weiye Chen; Dongming Zhao; Xijun He; Renqiang Liu; Zilong Wang; Xianfeng Zhang; Fang Li; Dan Shan; Hefeng Chen; Jiwen Zhang; Lulu Wang; Zhiyuan Wen; et al. (Science China Life Sciences, 2020)

Home for Marine Species: Seagrass Leaves as Vital Spawning Grounds and Food Source - Zhijian Jiang; Delian Huang; Yang Fang; Lijun Cui; Chunyu Zhao; Songlin Liu; Yunchao Wu; Qiming Chen; Chanaka Isuranga Premarathne Maha Ranvilage; Jialu He; Xiaoping Huang (Frontiers in Marine Science, 2020)

Experimental and Estimation Studies of Resilient Modulus of Marine Coral Sand under Cyclic Loading - Shao-Heng He; Qiong-Fang Zhang; Zhi Ding; Tang-Dai Xia; Xiao-Lu Gan (Journal of Marine Science and Engineering, 2020)
Coral sand is an important filler resource that can solve the shortage of terrestrial fillers in coastal areas. Recently, the foundations of many infrastructures in the South China Sea have been built with coral sand as fillers, which have been subjected to wave and traffic cyclic loads. Resilient modulus (Mr) is an important design parameter in marine engineering, but there are few studies on the resilient modulus response of coral sand under cyclic loading. A series of drained cyclic triaxial tests were carried out to investigate the effects of the initial mean effective stress (p0) and cyclic stress ratio (ζ) on the resilient modulus response of the coral sand from the South China Sea. The change of fractal dimension (αc) can reflect the rule of particle breakage evolution. The αc of coral sand shows a tendency of almost maintaining stable and then increasing rapidly with the increase of mean effective stress p0 under each cyclic stress ratio ζ. There is a threshold of p0, when the p0 exceeds this threshold, αc will increase significantly with the increase of p0. The increase of p0 has a beneficial effect on the improvement of the Mr, while the increase of ζ has both beneficial and detrimental effects on the improvement of the Mr. A new prediction model of the Mr considering particle breakage was established, which can better predict the Mr of coral sand in the whole stress interval. The research results can provide guidance for the design of marine transportation infrastructures, which can promote the development of marine transportation industry and energy utilization.

Three new ɑ-pyrone derivatives induced by chemical epigenetic manipulation of Penicillium herquei , an endophytic fungus isolated from Cordyceps sinensis - Da-Le Guo; Ling Qiu; Dan Feng; Xin He; Xiao-Hua Li; Zhi-Xing Cao; Yu-Cheng Gu; Ling Mei; Fang Deng; Yun Deng (Natural Product Research, 2020)

NAC transcription factors from Aegilops markgrafii reduce cadmium concentration in transgenic wheat - Xuye Du; Fang He; Bin Zhu; Mingjian Ren; Heng Tang (Plant and Soil, 2020)

The effects of Japanese encephalitis virus antibodies on Zika virus infection - Xiaoen He; Xinyue Lang; Jianhai Yu; Li Zhu; Zhiran Qin; Xuling Liu; Pei Chen; Chengguqiu Dai; Tingting Chen; Xujuan Li; Yangyang Chen; Dongrui Zhou; et al. (Medical Microbiology and Immunology, 2020)

Experimental study on the effects of tree planting on slope stability - Huijuan Lan; Daojie Wang; Songtang He; Yingchao Fang; Wenle Chen; Peng Zhao; Yuchao Qi (Landslides, 2020)

To what extent did changes in temperature affect China's socioeconomic development from the Western Han Dynasty to the Five Dynasties period? - Jia He; Yun Su; Xiuqi Fang (Journal of Quaternary Science, 2020)
Analysing the contribution of climate and non‐climate change factors to social development and the occurrence of historical events represents important research on the impact of climate change. This study identifies combinations of social subsystem indices affected by temperature changes using the conceptual framework of food security, a priori knowledge and logical reasoning to statistically analyse three 10‐year data series (grain harvest grades, famine indices and economic levels) from the Western Han Dynasty to the Five Dynasties period of ancient China (210 bc to 960 ad ). The results are as follows. For 94 of the 118 decades in the study period, social development was relatively directly related to temperature effects. On a decadal scale, against a cold background, grain production was closely related to temperature conditions in 40.7% of all decades. Economic prosperity and depressions in 5.1 and 21.2% of these decades, respectively, were directly related to temperature effects. Against a warm background, grain production was closely related to temperature conditions in 39% of all decades. Economic prosperity and depressions in 22 and 8.5% of these decades, respectively, were directly related to the temperature effects. The century and decadal‐scale characteristics were the same. Specifically, when mostly negative combinations of natural–socioeconomic factors dominated, the proportion of decades was slightly higher in cold than in warm periods. This case study enables a scientific understanding of the effect of changes in mean climate values/trends on social development and further demonstrates the different effects of the climate change process and mechanism. Climate cooling and warming may bring more positive than negative impacts in some regions and more negative than positive impacts in others. Complex feedback may amplify or reduce the impact of climate cooling and warming. Climate that evolves unfavourably has an impact more strongly correlated with the socioeconomic system's vulnerability and adaptability. © 2020 John Wiley & Sons, Ltd.

Hostaflavanol A, a new anti-inflammatory and antioxidant activities flavanol from the flowers of Hosta plantaginea - Li Yang; Yi-min Lin; Zhong-wei He; Ting-fang Zhang; Yu Li; Xiao-tong Xie; Yi-feng Wu; Jun-wei He (Medicinal Chemistry Research, 2020)

Quantitative Trait Locus Mapping for Yield-Associated Agronomic Traits in a BC2F6 Population of Japonica Hybrid Rice Liaoyou 5218 - Zhibin Li; Zetian Hua; Li Dong; Wei Zhu; Guangsheng He; Lijun Qu; Na Qi; Zhengjin Xu; Fang Wang (Journal of Plant Growth Regulation, 2020)

Identification of Mycobacterium abscessus species and subspecies using the Cas12a/sgRNA-based nucleic acid detection platform - Guohui Xiao; Su Zhang; Zhihang Liang; Guanqiang Li; Mutong Fang; Yaya Liu; Juanjuan Zhang; Min Ou; Xing He; Tianyu Zhang; Changchun Zeng; Lei Liu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Global vegetation biomass production efficiency constrained by models and observations - Yue He; Shushi Peng; Yongwen Liu; Xiangyi Li; Kai Wang; Philippe Ciais; M. Altaf Arain; Yuanyuan Fang; Joshua B. Fisher; Daniel Goll; Daniel Hayes; Deborah N. Huntzinger; et al. (Global Change Biology, 2020)
Plants use only a fraction of their photosynthetically derived carbon for biomass production (BP). The biomass production efficiency (BPE), defined as the ratio of BP to photosynthesis, and its variation across and within vegetation types is poorly understood, which hinders our capacity to accurately estimate carbon turnover times and carbon sinks. Here, we present a new global estimation of BPE obtained by combining field measurements from 113 sites with 14 carbon cycle models. Our best estimate of global BPE is 0.41 ± 0.05, excluding cropland. The largest BPE is found in boreal forests (0.48 ± 0.06) and the lowest in tropical forests (0.40 ± 0.04). Carbon cycle models overestimate BPE, although models with carbon–nitrogen interactions tend to be more realistic. Using observation‐based estimates of global photosynthesis, we quantify the global BP of non‐cropland ecosystems of 41 ± 6 Pg C/year. This flux is less than net primary production as it does not contain carbon allocated to symbionts, used for exudates or volatile carbon compound emissions to the atmosphere. Our study reveals a positive bias of 24 ± 11% in the model‐estimated BP (10 of 14 models). When correcting models for this bias while leaving modeled carbon turnover times unchanged, we found that the global ecosystem carbon storage change during the last century is decreased by 67% (or 58 Pg C).

Does dietary intake of selenium protect against cancer? A systematic review and meta-analysis of population-based prospective studies - Angelica Kuria; Xin Fang; Mei Li; Hedong Han; Jia He; Jan Olav Aaseth; Yang Cao (Critical Reviews in Food Science and Nutrition, 2020)

Decreased circadian fluctuation in cognitive behaviors and synaptic plasticity in APP/PS1 transgenic mice - Yexin He; Yiying Li; Fang Zhou; Jinshun Qi; Meina Wu (Metabolic Brain Disease, 2020)

Psychometric Testing of the Chinese Version of Supportive Care Needs Survey for Partners and Caregivers of Cancer Patients - Jing-jing Liu; Qun-hui Liu; Hong-ye He; Tian Zhang; Yong-xia Song; Wenru Wang; Jing-fang Hong (Journal of Cancer Education, 2020)

Construction of calcitonin gene-related peptide-modified mesenchymal stem cells and analysis of their effects on the migration and proliferation of vascular smooth muscle cells - Panke Chen; Fang He; Tao Liu; Shuai Ma; Bei Shi (In Vitro Cellular & Developmental Biology - Animal, 2020)

Research on the relationship between energy consumption and air quality in the Yangtze River Delta of China: an empirical analysis based on 20 sample cities - Lingyun He; Fang Yin; Deqing Wang; Xiaolei Yang; Fengmin Xie (Environmental Science and Pollution Research, 2020)

Correction to: Bioaccumulation and growth characteristics of Vallisneria natans (Lour.) Hara after chronic exposure to metal-contaminated sediments - Yu Qian; Changlei Cheng; Ken Drouillard; Qingzhi Zhu; Huan Feng; Shuzhuang He; Yuhong Fang; Shinan Qiao; Marek Kolenčík; Xuexiu Chang (Environmental Science and Pollution Research, 2020)

A simple and low-energy method to prepare loratadine nanosuspensions for oral bioavailability improvement: preparation, characterization, and in vivo evaluation - Dandan Yang; Ruirui Li; Fang Zhang; Li Qin; Feifei Peng; Shanshan Jiang; Huiyang He; Xiumei Lu; Peng Zhang (Drug Delivery and Translational Research, 2020)

miR-142a-3p promotes the proliferation of porcine hemagglutinating encephalomyelitis virus by targeting Rab3a - Peng Fan; Jiyu Guan; Wenqi He; Xiaoling Lv; Shiyu Hu; Yungang Lan; Kui Zhao; Feng Gao; Fang Li; Gencheng Fan; Hongbin He; Zi Li (Archives of Virology, 2020)

Compound C attenuates NLRP3 inflammasome despite AMPK knockdown in LPS plus palmitate-induced THP-1 cells - Yuxing Liu; Honghui He; Liangliang Fan; Jingjing Yuan; Hao Huang; Wenjun Yang; Linghao Wang; Zhaohui Mo; Fang Wang (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

RETRACTED ARTICLE: Emerging protective roles of shengmai injection in septic cardiomyopathy in mice by inducing myocardial mitochondrial autophagy via caspase-3/Beclin-1 axis - Yan Cao; Xiaotong Han; Hongwei Pan; Yu Jiang; Xiang Peng; Weiwei Xiao; Jingjing Rong; Fang Chen; Jin He; Lianhong Zou; Yi Tang; Yanfang Pei; et al. (Inflammation Research, 2020)

Evaluation of the genetic diversity of mango (Mangifera indica L.) seedling germplasm resources and their potential parents with start codon targeted (SCoT) markers - Li Zhou; Xin-Hua He; Hai-Xia Yu; Mei-Yan Chen; Yan Fan; Xiu-Juan Zhang; Zhong-Bing Fang; Cong Luo (Genetic Resources and Crop Evolution, 2020)

Water masses influence bacterioplankton community structure in summer Kongsfjorden - Shunan Cao; Fang Zhang; Jianfeng He; Zhongqiang Ji; Qiming Zhou (Extremophiles, 2020)

Risk profiling using metabolomic characteristics for susceptible individuals of drug-induced liver injury caused by Polygonum multiflorum - Le Zhang; Ming Niu; Ai-wu Wei; Jin-fa Tang; Can Tu; Zhao-fang Bai; Zheng-sheng Zou; Xiao-he Xiao; You-ping Liu; Jia-bo Wang (Archives of Toxicology, 2020)

TRY plant trait database – enhanced coverage and open access - Jens Kattge; Gerhard Bönisch; Sandra Díaz; Sandra Lavorel; Iain Colin Prentice; Paul Leadley; Susanne Tautenhahn; Gijsbert D. A. Werner; Tuomas Aakala; Mehdi Abedi; Alicia T. R. Acosta; George C. Adamidis; et al. (Global Change Biology, 2020)
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits—almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.

Regional assimilation of in situ observed soil moisture into the VIC model considering spatial variability - Jianhong Zhou; Zhiyong Wu; Hai He; Fang Wang; Zhengguang Xu; Xiaotao Wu (Hydrological Sciences Journal, 2019)

Bifidobacterium bifidum TMC3115 Can Characteristically Influence Glucose and Lipid Profile and Intestinal Microbiota in the Middle-Aged and Elderly - Ke Wang; Xiaohong Yu; Yi Li; Yun Guo; Lin Ge; Fangfang Pu; Xinying Ma; Wenjing Cui; Francesco Marrota; Fang He; Ming Li (Probiotics and Antimicrobial Proteins, 2019)

Expression and localization of the small proteoglycans decorin and biglycan in articular cartilage of Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency - Mengying Wang; Senhai Xue; Qian Fang; Meng Zhang; Ying He; Ying Zhang; Mikko J. Lammi; Junling Cao; Jinghong Chen (Glycoconjugate Journal, 2019)

Municipal Wastewater Enriched with Trace Metals for Enhanced Lipid Production of the Biodiesel-Promising Microalga Scenedesmus obliquus - Song-Fang Han; Wenbiao Jin; Abd El-Fatah Abomohra; Renjie Tu; Xu Zhou; Zhongqi He; Chuan Chen; Guo-jun Xie (BioEnergy Research, 2019)

A new phenolic glycoside from the Idesia polycarpa Maxim. leaves - Lei Huang; Tong Peng; Yu Li; Yunyun He; Li Wang; Shiyan Zhang; Yiran Sun; Fang Chen; Lin Tang (Natural Product Research, 2019)

ATRA induces the differentiation of hepatic progenitor cells by upregulating microRNA-200a - Chaoqun Hu; Xiaohua Liang; Shuyu Fang; Lei Xu; Mengjia Gong; Yi Wang; Yang Bi; Siqi Hong; Yun He (In Vitro Cellular & Developmental Biology - Animal, 2019)

Effect of agmatine on food intake in mandarin fish (Siniperca chuatsi) - Liyuan Lv; Xu-Fang Liang; Kang Huang; Shan He (Fish Physiology and Biochemistry, 2019)

Penicillilactone A, a novel antibacterial 7-membered lactone derivative from the sponge-associated fungus Penicillium sp. LS54 - Yong Liu; Lijian Ding; Fang Fang; Shan He (Natural Product Research, 2019)

Soil organic carbon components in inner Mongolian shrub-encroached grasslands - Luhong Zhou; Haihua Shen; Yunping Xu; He Li; Leiyi Chen; Yinghui Wang; Pujin Zhang; Xia Zhao; Taoyu Liu; Huifeng Hu; Jingyun Fang (Plant and Soil, 2019)

The effects of simulated deposited nitrogen on nutrient dynamics in decomposing litters across a wide quality spectrum using a 15N tracing technique - Xue-Min Ye; Yang Zhang; Fu-Sheng Chen; G. Geoff Wang; Xiang-Min Fang; Xiao-Fan Lin; Song-Ze Wan; Ping He (Plant and Soil, 2019)

A global database of paired leaf nitrogen and phosphorus concentrations of terrestrial plants - Di Tian; Jens Kattge; Yahan Chen; Wenxuan Han; Yongkai Luo; Jinsheng He; Huifeng Hu; Zhiyao Tang; Suhui Ma; Zhengbing Yan; Quanhong Lin; Bernhard Schmid; et al. (Ecology, 2019)
Nitrogen (N) and phosphorus (P) are essential components of the basic cell structure of plants. In particular, leaf N and P concentrations and their stoichiometric relationship largely determine the photosynthesis, growth, reproduction, and ecophysiological processes of plants. As important leaf functional traits, leaf N and P concentrations and their stoichiometric relationship play vital roles in indicating plant nutrient‐use strategies and their evolution in terrestrial ecosystems. They also influence physiological and ecological processes in leaves (e.g., growth rate and energy metabolism) and productivity (e.g., net primary production and net ecosystem production) at ecosystem level. However, the lack of a comprehensive data set containing paired leaf N and P concentration records has distinctly limited research on nutrient stoichiometry and leaf functional traits. Here, we provide a global database of paired records of leaf N and P concentrations. A total of 11,354 individual records were acquired spanning 1,291 sites worldwide, including 201 families, 1,265 genera, and 3,227 species. The records span a latitudinal range of 45.28 °S to 68.35 °N and a longitudinal range of 155.5 °W to 168.0 °E. The variables provided for each individual record are (1) geographical location (longitude, latitude, and altitude); (2) matched leaf N and P concentrations and N:P ratio; (3) taxonomic information (family, genera, and species); (4) life form (angiosperm/gymnosperm, monocotyledonous/dicotyledonous and woody plants/herbaceous plants; note that woody plants were further divided into coniferous, deciduous broad‐leaved, and evergreen broad‐leaved woody species and that herbaceous plants were further divided into annual and perennial species); (5) mean annual temperature ( MAT ) and mean annual precipitation ( MAP ); and (6) soil N and P concentrations and pH value in some records. To date, this database is the world's largest database of paired leaf N and P concentrations, which contains matched information of geographical location, environmental factors, and taxa. We believe that the database will play a fundamental and crucial part of ecological stoichiometric studies. There are no copyright restrictions. When using this database, we kindly request that you cite this article, respecting all the authors’ hard work during sample collection and data compilation.

NIS and epithelial-mesenchymal transition marker expression of circulating tumor cells for predicting and monitoring the radioactive iodine-131 therapy effect in differentiated thyroid cancers - Lei Zheng; Guiyu Wang; Wei Guo; Deng Pan; Laiping Xie; Song He; Chaoxue Luo; Hongmin Li; Yaling Ran; Shiyang Wu; Fang Liu; Xiaoli Zhang; et al. (Molecular Biology Reports, 2019)

Phosphorylation residue T175 in RsbR protein is required for efficient induction of sigma B factor and survival of Listeria monocytogenes under acidic stress - Ke He; Yong-ping Xin; Ying Shan; Xian Zhang; Hou-hui Song; Wei-huan Fang (Journal of Zhejiang University-SCIENCE B, 2019)

Spatiotemporal characteristics of precipitation diurnal variations in Chongqing with complex terrain - Shaoying Chen; Yan Yan; Gang Liu; Dexian Fang; Zheng Wu; Jun He; Jianping Tang (Theoretical and Applied Climatology, 2019)

Regulatory network reconstruction of five essential microRNAs for survival analysis in breast cancer by integrating miRNA and mRNA expression datasets - Kan He; Wen-Xing Li; Daogang Guan; Mengting Gong; Shoudong Ye; Zekun Fang; Jing-Fei Huang; Aiping Lu (Functional & Integrative Genomics, 2019)

Bioaccumulation and growth characteristics of Vallisneria natans (Lour.) Hara after chronic exposure to metal-contaminated sediments - Yu Qian; Changlei Cheng; Ken Drouillard; Qingzhi Zhu; Huan Feng; Shuzhuang He; Yuhong Fang; Shinan Qiao; Marek Kolenčíka; Xuexiu Chang (Environmental Science and Pollution Research, 2019)

Dark septate endophytes improve the growth of host and non-host plants under drought stress through altered root development - Xia Li; Chao He; Xueli He; Fang Su; Lifeng Hou; Ying Ren; Yiting Hou (Plant and Soil, 2019)

SAMD9 is a (epi-) genetically regulated anti-inflammatory factor activated in RA patients - Pei He; Long-Fei Wu; Peng-Fei Bing; Wei Xia; Lan Wang; Fang-Fei Xie; Xin Lu; Shu-Feng Lei; Fei-Yan Deng (Molecular and Cellular Biochemistry, 2019)

Roles of eNOS in atherosclerosis treatment - Fen-fang Hong; Xiao-yu Liang; Wei Liu; Sha Lv; Shu-jin He; Hai-bin Kuang; Shu-long Yang (Inflammation Research, 2019)

Allocating on coal consumption and CO2 emission from fair and efficient perspective: empirical analysis on provincial panel data of China - Bang-jun Wang; Jia-lu Zhao; Yan-fang Wu; Chao-qun Zhu; Yin-nan He; Yi-xi Wei (Environmental Science and Pollution Research, 2019)

Molecular transformation of dissolved organic matter in high-temperature hydrogen peroxide oxidation of a refinery wastewater - Xiaocun Zhuo; Haiyan Huang; Fang Lan; Chen He; Qiong Pan; Yahe Zhang; Quan Shi (Environmental Chemistry Letters, 2019)

Sediment load change with erosion processes under simulated rainfall events - Liying Sun; Haiyan Fang; Qiangguo Cai; Xihua Yang; Jijun He; John L. Zhou; Xunming Wang (Journal of Geographical Sciences, 2019)

Water limitation mitigates high-temperature stress injuries in grapevine cultivars through changes in photosystem II efficiency and antioxidant enzyme pathways - Qian Zha; Xiaojun Xi; Yani He; Aili Jiang; Xianping Fang (Acta Physiologiae Plantarum, 2019)

Long-lasting impairments in rodent oxygen-induced retinopathy measured by retinal vessel density and visual function - Xu Wang; Ke Shen; Fang Lu; Shigang He (Science China Life Sciences, 2019)

Complex roles of necroptosis in cancer - Fang Zhu; Wei Zhang; Tao Yang; Su-dan He (Journal of Zhejiang University-SCIENCE B, 2019)

Polychlorinated naphthalene emissions to the atmosphere from typical secondary aluminum smelting plants in southwestern China: concentrations, characterization, and risk evaluation - Yanyan Fang; Zhiqiang Nie; Jinzhong Yang; Qingqi Die; Jie He; Hongjin Yu; Qi Zhou; Qifei Huang (Environmental Science and Pollution Research, 2019)

A facile extraction of keratin from pig hair and its properties - Quan-Fang Li; Yufeng He; Rong-Min Wang (Biologia, 2019)

Chemical composition and health risk indices associated with size-resolved particulate matter in Pearl River Delta (PRD) region, China - Dongqing Fang; Wei Huang; Dagmara S. Antkiewicz; Yuqin Wang; Reza Bashiri Khuzestani; Yang Zhang; Jing Shang; Martin M. Shafer; Lingyan He; James J. Schauer; Yuanxun Zhang; Shuo Zhao (Environmental Science and Pollution Research, 2019)

Selenium Rescues Aflatoxin B1-Inhibited T Cell Subsets and Cytokine Levels in Cecal Tonsil of Chickens - Fengyuan Wang; Zhicai Zuo; Kejie Chen; Xi Peng; Jing Fang; Hengmin Cui; Gang Shu; Min He; Li Tang (Biological Trace Element Research, 2019)

Purification of the total steroidal saponins from fenugreek seeds ( Trigonella foenum - graecum L.) using aqueous two-phase system and determination of diosgenin content using micellar electrokinetic chromatography method - Na Wang; Famei He; Wenliang Li; Xu Fang; Hailing Li (Natural Product Research, 2019)

Magnetic nanoferromanganese oxides modified biochar derived from pine sawdust for adsorption of tetracycline hydrochloride - Jie Liang; Yilong Fang; Yuan Luo; Guangming Zeng; Jiaqin Deng; Xiaofei Tan; Ning Tang; Xuemei Li; Xinyue He; Chunting Feng; Shujing Ye (Environmental Science and Pollution Research, 2019)

Direct and indirect effects of climate on richness drive the latitudinal diversity gradient in forest trees - Chengjin Chu; James A. Lutz; Kamil Král; Tomáš Vrška; Xue Yin; Jonathan A. Myers; Iveren Abiem; Alfonso Alonso; Norm Bourg; David F.R.P. Burslem; Min Cao; Hazel Chapman; et al. (Ecology Letters, 2019)
Climate is widely recognised as an important determinant of the latitudinal diversity gradient. However, most existing studies make no distinction between direct and indirect effects of climate, which substantially hinders our understanding of how climate constrains biodiversity globally. Using data from 35 large forest plots, we test hypothesised relationships amongst climate, topography, forest structural attributes (stem abundance, tree size variation and stand basal area) and tree species richness to better understand drivers of latitudinal tree diversity patterns. Climate influences tree richness both directly, with more species in warm, moist, aseasonal climates and indirectly, with more species at higher stem abundance. These results imply direct limitation of species diversity by climatic stress and more rapid (co‐)evolution and narrower niche partitioning in warm climates. They also support the idea that increased numbers of individuals associated with high primary productivity are partitioned to support a greater number of species.

Early Cretaceous rift-related volcanism in the Songliao Basin, NE China – A geochemical study - Shuang-Qing Li; Yan Wang; Bo-Wen Fang; Jian-Feng He; Fukun Chen; Wolfgang Siebel (International Geology Review, 2019)

Isolation and characterization of mineral-dissolving bacteria from different levels of altered mica schist surfaces and the adjacent soil - Yuan Li Wang; Qi Wang; Rui Yuan; Xia Fang Sheng; Lin Yan He (World Journal of Microbiology and Biotechnology, 2019)