Discerning the Putative U and V Chromosomes of Saccharina japonica (Phaeophyta) by Cytogenetic Mapping of Sex-Linked Molecular Markers - Yu Du; Peng-Fei Liu; Zhi Li; Qian Zheng; Yan-Hui Bi; Zhi-Gang Zhou (Frontiers in Marine Science, 2022)
Saccharina japonica , an importantly industrial species in brown seaweeds, has a typical alternate life history of heteromorphic generations and UV sex determination system. But up to now, the sex chromosomes, U and V, in this kelp remain to be evidenced cytologically. In the present study, the female-linked (SJ-f_000170 and MSj68-58-2) and male-linked (SJ-13_001840 and MSj68-16-2) molecular markers developed on the basis of Ectocarpus sex-determining regions (SDRs) were selected after PCR amplification and Southern blotting analysis. Mono-color fluorescence in situ hybridization (FISH) to the kelp metaphase chromosomes with each of these confirmed sex-linked markers as a probe indicated that the hybridization signals were confined to either female or male gametophytes exclusively. The shape and size of hybridized chromosomes and the relative location of these sex-linked markers on them suggested that the marked chromosomes in a sex were the same, which was further confirmed by dual-color FISH observations. SJ-f_000170 and SJ-13_001840, corresponding to each sex, were therefore used to map the sporophyte metaphase chromosomes by dual-color FISH technique, and they were hybridized on different chromosomes as expected. The sporophyte metaphase chromosomes as hybridized by SJ-f_000170 and SJ-13_001840 resembled those in either female or male gametophytes, suggesting that they were the putative U and V, respectively, chromosomes in S . japonica . To further demonstrate the reliability of this inference, genomic information of the screened bacterial artificial chromosome (BAC) clones carrying two female-linked markers, for example, from the constructed BAC libraries of the kelp female gametophytes was provided. The insert sequencing of two selected BAC clones revealed that repetitive elements were rich whereas gene density was poor, which was characterized as non-recombining SDR sequences in brown seaweed Ectocarpus sp. and liverwort Marchantia polymorpha . The present study laid a solid foundation for unveiling the mystery of S . japonica sex chromosomes.

Litter nitrogen concentration changes mediate effects of drought and plant species richness on litter decomposition - Jiang Wang; Yuan Ge; Johannes H. C. Cornelissen; Xiao-Yan Wang; Song Gao; Yi Bai; Tong Chen; Zhong-Wang Jing; Chong-Bang Zhang; Wen-Li Liu; Jun-Min Li; Fei-Hai Yu (Oecologia, 2022)

Why SNP rs3755955 is associated with human bone mineral density? A molecular and cellular study in bone cells - Pei He; Fei Jiang; Long-Fei Wu; Xu Zhou; Shu-Feng Lei; Fei-Yan Deng (Molecular and Cellular Biochemistry, 2022)

Development of the specific molecular markers of the thin-blade strain (HR-5) in Pyropia haitanensis - Hong-Chang Ding; Qin-Jiao Fei; Xing-Hong Yan (Journal of Applied Phycology, 2022)

Will the artificial populations be sustainable? A genetic assessment on Caragana korshinskii afforestation in the semiarid regions of North China - Xiaoyue Yin; Chaoju Qian; Xia Yan; Tingzhou Fang; Xingke Fan; Shanshan Zhou; Xiao-Fei Ma (European Journal of Forest Research, 2022)

Oxygen isotope temperature calibrations for modern Tridacna shells in western Pacific - Guozhen Wang; Hong Yan; Chengcheng Liu; Tao Han; Pengchao Zhou; Nanyu Zhao; Hanfeng Wen; Haobai Fei; John Dodson (Coral Reefs, 2022)

Overexpression of miR-122 Impairs Intestinal Barrier Function and Aggravates Acute Pancreatitis by Downregulating Occludin Expression - Wei Yang; Hong-Wei Xu; Xi-Rong Lu; Qian-Fei Xu; Ming-Hao Tao; Yan-Miao Dai (Biochemical Genetics, 2022)

Numerical investigation of the control factors driving Zhe-Min Coastal Current - Yang Zhang; Fei Chai; Joseph Zhang; Yang Ding; Min Bao; Yunwei Yan; Hong Li; Wei Yu; Liang Chang (Acta Oceanologica Sinica, 2022)

Climate warming promotes deterministic assembly of arbuscular mycorrhizal fungal communities - Xinyu Xu; Yunpeng Qiu; Kangcheng Zhang; Fei Yang; Mengfei Chen; Xi Luo; Xuebin Yan; Peng Wang; Yi Zhang; Huaihai Chen; Hui Guo; Lin Jiang; et al. (Global Change Biology, 2022)
Arbuscular mycorrhizal fungi (AMF) significantly contribute to plant resource acquisition and play important roles in mediating plant interactions and soil carbon (C) dynamics. However, it remains unclear how AMF communities respond to climate change. We assessed impacts of warming and precipitation alterations (30% increase or decrease) on soil AMF communities, and examined major ecological processes shaping the AMF community assemblage in a Tibetan alpine meadow. Our results showed that warming significantly increased root biomass, and available nitrogen (N) and phosphorus (P) in soil. While precipitation alterations increased AMF abundances, they did not significantly affect the composition or diversity of AMF communities. In contrast, warming altered the composition of AMF communities and reduced their Shannon–Wiener index and Pielou's evenness. In particular, warming shifted the AMF community composition in favor of Diversisporaceae over Glomeraceae, likely through its impact on soil N and P availability. In addition, AMF communities were phylogenetically random in the unwarmed control but clustered in warming plots, implying more deterministic community assembly under climate warming. Warming enhancement of root growth, N and P availability likely reduced plant C‐allocation to AMF, imposing stronger environmental filtering on AMF communities. We further proposed a conceptual framework that integrates biological and geochemical processes into a mechanistic understanding of warming and precipitation changes’ effects on AMF. Taken together, these results suggest that soil AMF communities may be more sensitive to warming than expected, highlighting the need to monitor their community structure and associated functional consequences on plant communities and soil C dynamics under the future warmer climate.

Two new nor -lignans from Selaginella pulvinata (Hook. & Grev.) Maxim and their antihyperglycemic activities - Hua-Wei Lv; Yu-Xia Li; Meng Luo; Jia-Meng Qi; Ze-Fei Fu; Hong-Jian Zhang; Yuan-Qiang Guo; Chu Chu; Han-Bing Li; Ji-Zhong Yan (Natural Product Research, 2022)

Taxonomical and functional bacterial community selection in the rhizosphere of the rice genotypes with different nitrogen use efficiencies - Wei Chen; Yan Gao; Jie Yang; Fangjun Fan; Weiguo Zhang; Jiangye Li; Cong Zhou; Gaoling Shi; Fei Tong; Guangping Fan (Plant and Soil, 2022)

Correction to: Physalin A induces G2/M phase cell cycle arrest in human non-small cell lung cancer cells: involvement of the p38 MAPK/ROS pathway - Ning Kang; Jun-feng Jian; Shi-jie Cao; Qiang Zhang; Yi-wei Mao; Yi-yuan Huang; Yan-fei Peng; Feng Qiu; Xiu-mei Gao (Molecular and Cellular Biochemistry, 2022)

Retraction Note to: Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes - Michael Nothnagel; Guangyao Fan; Fei Guo; Yongfeng He; Yiping Hou; Shengping Hu; Jiang Huang; Xianhua Jiang; Wook Kim; Kicheol Kim; Chengtao Li; Hui Li; et al. (Human Genetics, 2022)

Azospirillum tabaci sp. nov., a bacterium isolated from rhizosphere soil of Nicotiana tabacum L - Yan-Qing Duan; Xing-Kui Zhou; Neeli Habib; Shi-Qiang Gao; Li-Min Dong; Xiao-Fei Liu; Yang-Mei Shi; Wen-Jun Li; Gang Du (Archives of Microbiology, 2022)

Mesorhizobium xinjiangense sp. nov., isolated from rhizosphere soil of Alhagi sparsifolia - Dong Meng; Yu-Ling Liu; Jun-Jie Zhang; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Heng Meng; Zong-Jun Du; Wei-Min Li; Qiang Li (Archives of Microbiology, 2022)

Study on Dynamic Characteristics of Diorite Under Dry–Wet Cycle - Jiangbo Xu; Haohui Sun; Yilun Cui; Dongyang Fei; Hengxing Lan; Changgen Yan; Han Bao; Faquan Wu (Rock Mechanics and Rock Engineering, 2021)

A case study on the triggering mechanisms of localized warm-sector rainstorm - Lihua He; Linxue Long; Biying Chen; Yongqing Wang; Fei Geng; Xuejin Yan (Meteorology and Atmospheric Physics, 2021)

Characterization of the novel hybrid cultivar E25 of Saccharina japonica in the northern farming region of China - Li Su; Ti Feng Shan; Jing Li; Su Qin Gao; Shao Jun Pang; Xiao Fei Leng; Yan Zhang; Ming Fu Zhang; Hong Tao Gao (Journal of Applied Phycology, 2021)

Treatment of the actual landfill leachate in different constructed wetlands through intermittent and varied aeration mode - Yi Wang; Wen-Huai Wang; Heng Zhang; Fei-Long Yan; Jia-Jun Li (Environmental Science and Pollution Research, 2021)

Detection of anthropogenically driven trends in Arctic amplification - Yu Wang; Pengcheng Yan; Taichen Feng; Fei Ji; Shankai Tang; Guolin Feng (Climatic Change, 2021)

Identification and Expression of PPAR in Sinonovacula constricta and Their Potential Regulatory Effects on Δ6 Fad Transcription - Zhaoshou Ran; Fei Kong; Kai Liao; Jilin Xu; Xingwang Liu; Peng Shi; Mengqi Zhang; Kaibin Wu; Xiaojun Yan (Journal of Ocean University of China, 2021)

Summery Intra-Tidal Variations of Suspended Sediment Transportation – Topographical Response and Dynamical Mechanism in the Aoshan Bay and Surrounding Area, Shandong Peninsula - Yan Wang; Yanguang Dou; Liang Zou; Fei Gao; Dapeng Su; Rui Hu; Baojing Yue; Biying Xue (Journal of Ocean University of China, 2021)

Complete genome sequence of a putative novel ilarvirus isolated from Eleocharis dulcis - Lanqing Lv; Xinyang Wu; Jiajia Weng; Yuchao Lai; Kelei Han; Yuwen Lu; Jiejun Peng; Lin Lin; Shaofei Rao; Guanwei Wu; Jianping Chen; Hongying Zheng; et al. (Archives of Virology, 2021)

Pandemic threat posed by H3N2 avian influenza virus - Yaping Zhang; Conghui Zhao; Yujie Hou; Yan Chen; Fei Meng; Yichao Zhuang; Liling Liu; Yasuo Suzuki; Jianzhong Shi; Guohua Deng; Hualan Chen (Science China Life Sciences, 2021)

Correlation between the positive rate of SAA in children with respiratory tract infection and ambient temperature - Shanshui Zeng; Mengru Han; Fei Liu; Yan Long; Ming Jiang; Hongling Yang (Environmental Science and Pollution Research, 2021)

Substrate damage and recovery after giant clam shell mining at remote coral reefs in the southern South China Sea - Shengnan Zhou; Qi Shi; Hongqiang Yang; Xiyang Zhang; Xiaoju Liu; Fei Tan; Pin Yan (Journal of Geographical Sciences, 2021)

Reduced acetylcholine and elevated muscarinic receptor 2 in duodenal mucosa contribute to the impairment of mucus secretion in 6-hydroxydopamine-induced Parkinson’s disease rats - Jing-Ting Yan; Xiao-Yu Liu; Jing-Hua Liu; Guang-Wen Li; Li-Fei Zheng; Xiao-Li Zhang; Yue Zhang; Xiao-Yan Feng; Jin-Xia Zhu (Cell and Tissue Research, 2021)

Complete Coverage Path Planning of an Unmanned Surface Vehicle Based on a Complete Coverage Neural Network Algorithm - Peng-Fei Xu; Yan-Xu Ding; Jia-Cheng Luo (Journal of Marine Science and Engineering, 2021)
In practical applications, an unmanned surface vehicle (USV) generally employs a task of complete coverage path planning for exploration in a target area of interest. The biological inspired neural network (BINN) algorithm has been extensively employed in path planning of mobile robots, recently. In this paper, a complete coverage neural network (CCNN) algorithm for the path planning of a USV is proposed for the first time. By simplifying the calculation process of the neural activity, the CCNN algorithm can significantly reduce calculation time. To improve coverage efficiency and make the path more regular, the optimal next position decision formula combined with the covering direction term is established. The CCNN algorithm has increased moving directions of the path in grid maps, which in turn has further reduced turning-angles and makes the path smoother. Besides, an improved A* algorithm that can effectively decrease path turns is presented to escape the deadlock. Simulations are carried out in different environments in this work. The results show that the coverage path generated by the CCNN algorithm has less turning-angle accumulation, deadlocks, and calculation time. In addition, the CCNN algorithm is capable to maintain the covering direction and adapt to complex environments, while effectively escapes deadlocks. It is applicable for USVs to perform multiple engineering missions.

Cytochalasins from endophytic Diaporthe sp. GDG-118 - Xishan Huang; Dexiong Zhou; Yan Liang; Xiaobo Liu; Fei Cao; Yuyue Qin; Tuxiang Mo; Zhaolong Xu; Jun Li; Ruiyun Yang (Natural Product Research, 2021)

Liquid–Solid Flow Characteristics in Vertical Swirling Hydraulic Transportation with Tangential Jet Inlet - Jiyang Qi; Jie Yin; Fei Yan; Ping Liu; Tieli Wang; Chen Chen (Journal of Marine Science and Engineering, 2021)
In order to improve the efficiency and safety of vertical hydraulic transport systems for non-spherical particles, a new pipeline transport system with a tangential jet inlet is adopted in this study, and a modified non-spherical drag coefficient model is used to analyze the liquid–solid flow characteristics based on the CFD-DEM (Computational Fluid Dynamics-Discrete Element Method) coupling method. The focus of the study is on the influence of different tangential flow proportions in terms of the velocity distribution, the vorticity, the total pressure, the concentration and drag force of particles of various shapes. The conveying efficiency is measured according to the fluid velocity distribution and the particle concentration, and the safety of conveying is evaluated according to the flow structure and drag force of the particles. The result shows that the velocity of the swirling pipes is significantly higher than the straight pipe. With the increase of the tangential flow proportion, the swirling number and the vorticity magnitude increase, and the vortex core is broken and merged more quickly. Furthermore, the concentration gap and axial drag force gap between particles of various shapes are reduced with the effect of swirling flow, the particle concentration increases, and the particles of each component are uniformly mixed and transported.

Transcriptional memory and response to adverse temperatures in plants - Wei Xie; Qianqian Tang; Fei Yan; Zeng Tao (Journal of Zhejiang University-SCIENCE B, 2021)

Jiella mangrovi sp. nov., a novel endophytic bacterium isolated from leaf of Rhizophora stylosa - Ming-Sheng Chen; Fei-Na Li; Xiao-Hui Chen; Zi-Hao Huang; Xiao-Rui Yan; Li Tuo (Antonie van Leeuwenhoek, 2021)

Record Arctic Ozone Loss in Spring 2020 is Likely Caused by North Pacific Warm Sea Surface Temperature Anomalies - Yan Xia; Yongyun Hu; Jiankai Zhang; Fei Xie; Wenshou Tian (Advances in Atmospheric Sciences, 2021)

Association between large artery stenosis, cerebral small vessel disease and risk of ischemic stroke - Fei Han; Ding-Ding Zhang; Fei-Fei Zhai; Jun Xue; Jiang-Tao Zhang; Shuang Yan; Li-Xin Zhou; Jun Ni; Ming Yao; Meng Yang; Ming-Li Li; Zheng-Yu Jin; et al. (Science China Life Sciences, 2021)

Magnetic Resonance Imaging-Guided and Navigated Individualized Repetitive Transcranial Magnetic Stimulation for Cognitive Impairment in Schizophrenia - Xu-Sha Wu; Tian-Cai Yan; Xian-Yang Wang; Yang Cao; Xiao-Fan Liu; Yu-Fei Fu; Lin Wu; Yin-Chuan Jin; Hong Yin; Long-Biao Cui (Neuroscience Bulletin, 2021)

Organic acid metabolites involved in local adaptation to altitudinal gradient in Agriophyllum squarrosum, a desert medicinal plant - Shanshan Zhou; Jian Yang; Chaoju Qian; Xiaoyue Yin; Xia Yan; Xingke Fan; Tingzhou Fang; Yuan Gao; Yuxiao Chang; Xiao-Fei Ma (Journal of Plant Research, 2021)

Characterization of a transcription factor SlNAC7 gene from Suaeda liaotungensis and its role in stress tolerance - Hong-Fei Wang; Hong-Yan Shan; He Shi; Dan-Dan Wu; Tong-Tong Li; Qiu-Li Li (Journal of Plant Research, 2021)

Influencing factors and physiochemical changes of embryogenesis through in vitro isolated microspore culture in Brassica species - Yan-Qi Dong; Yu-Hong Gao; Te Zhao; Guang-Qian Ren; Yan-Li Liu; Bin Guan; Rong-Xian Jin; Fei Gao; Yan-Li Zhang; Xiu-Fang Tan; Hong-Cai Zhu; Yu-Hong Zhang; et al. (Biologia, 2021)

Modulation of the 5-HT 3 A receptor current by desacylbaldrinal - Li-Xia Wang; Hu-Lan Chen; Hong-Ling Yan; Fei Tang; Hai Zhang; Hong-Xiang Li; Qiang Ye; Cheng Peng; Yu-Zhu Tan (Natural Product Research, 2021)

Effect of first-stage aeration on treatment of domestic sewage in different hybrid constructed wetlands - Fei-Long Yan; Yi Wang; Wen-Huai Wang; Heng Zhang; Yu-Cong Zheng; Xiao-Mei Kou; Shi-Zhang Wu; Tian Shao (Environmental Science and Pollution Research, 2021)

Soil actinobacteria tend to have neutral interactions with other co‐occurring microorganisms, especially under oligotrophic conditions - Bingfa Yan; Ning Liu; Minghao Liu; Xueyuan Du; Fei Shang; Ying Huang (Environmental Microbiology, 2021)
Summary Actinobacteria produce a variety of secondary metabolites that can influence the survival or behaviour of other organisms. The understanding of the ecological roles of actinobacteria has significantly improved in the past decades, but a systematic insight into the interactions between actinobacteria and other microbes in nature is warranted. Here, we studied the pairwise effects of actinobacteria on other microbes isolated from red soils under different nutritional conditions. We found that neutral effects dominated the interactions, accounting for 68.1% of the interactions in eutrophic conditions and for a significantly higher proportion (86.2%) in oligotrophic conditions. High nutrient levels boosted active metabolism of actinobacteria and generally made them more aggressive, supporting the stress gradient hypothesis. The secondary metabolites produced by actinobacteria played a pivotal role in interference competition with other microbes, of which the role of desferrioxamine siderophores could not be ignored. Niche overlap seemed to be another cause of competition, notably under oligotrophic conditions. Moreover, the large‐scale phylogeny had a much greater impact on the interaction than the location origin of the microbes. These results provide an understanding of the coexistence of actinobacteria with other microbes in nature and suggest neutrality as a key mechanism for maintaining microbial diversity in soils.

Shared genetic study gives insights into the shared and distinct pathogenic immunity components of IgA nephropathy and SLE - Yue-miao Zhang; Xu-jie Zhou; Yan-Na Wang; Xing-zi Liu; Yong-Fei Wang; Yu-lung Lau; Wan-ling Yang; Hong Zhang (Molecular Genetics and Genomics, 2021)

FSTL1 aggravates OVA-induced inflammatory responses by activating the NLRP3/IL-1β signaling pathway in mice and macrophages - Yan Wang; Dong Zhang; Tian Liu; Jun-fei Wang; Jin-xiang Wu; Ji-ping Zhao; Jia-wei Xu; Jin-tao Zhang; Liang Dong (Inflammation Research, 2021)

MFGE8 mitigates brain injury in a rat model of SAH by maintaining vascular endothelial integrity via TIGβ5/PI3K/CXCL12 signaling - Jikai Wang; Yiping Wang; Yuchun Zuo; Jiajia Duan; Aihua Pan; Jian-Ming Li; Xiao-Xin Yan; Fei Liu (Experimental Brain Research, 2021)

Deformation of the Zhangjiazhuang high-speed railway tunnel: an analysis of causal mechanisms using geomorphological surveys and D-InSAR monitoring - Xing-min Meng; Tian-jun Qi; Yan Zhao; Tom Dijkstra; Wei Shi; Yin-fei Luo; Yuan-zhao Wu; Xiao-jun Su; Fu-meng Zhao; Jin-hui Ma; Yi Zhang; Guan Chen; et al. (Journal of Mountain Science, 2021)

Potential sediment sources identification of debris flows in the Jiangjia Gully, China - Xia-fei Tian; Yong Li; Quan-yan Tian (Journal of Mountain Science, 2021)

Application of an enhanced BP neural network model with water cycle algorithm on landslide prediction - Yong-gang Zhang; Jun Tang; Rao-ping Liao; Ming-fei Zhang; Yan Zhang; Xiao-ming Wang; Zheng-yang Su (Stochastic Environmental Research and Risk Assessment, 2021)

The effect of organic solvent washing on the structure of hydrochar-based dissolved organic matters and its potential environmental toxicity - Guangping Fan; Fei Tong; Weiguo Zhang; Gaoling Shi; Wei Chen; Lizhu Liu; Jiangye Li; Zhenhua Zhang; Yan Gao (Environmental Science and Pollution Research, 2021)

Genesis of the Ordovician Ma55 sub-member dolomites in the Ordos Basin, China - Xiyan Yang; Yawen Li; Yan Zhan; Fei Huo; Xingzhi Wang (Carbonates and Evaporites, 2021)

Altered structural and functional connectivity in CSF1R-related leukoencephalopathy - Fei-Xia Zhan; Ze-Yu Zhu; Qing Liu; Hai-Yan Zhou; Xing-Hua Luan; Xiao-Jun Huang; Xiao-Li Liu; Wo-Tu Tian; Shi-Ge Wang; Xiao-Xuan Song; Guang Chen; Ming-Liang Zhao; et al. (Brain Imaging and Behavior, 2021)

Comparative transcriptome analysis to identify genes involved in terpenoid biosynthesis in Agriophyllum squarrosum, a folk medicinal herb native to Asian temperature deserts - Xiaoyue Yin; Xia Yan; Chaoju Qian; Shanshan Zhou; Tingzhou Fang; Xingke Fan; Yuan Gao; Yuxiao Chang; Jian Yang; Xiao-Fei Ma (Plant Biotechnology Reports, 2021)

Brachybacterium halotolerans sp. nov., a halotolerant, endophytic actinomycete isolated from branch of Bruguiera gymnoirhiza - Ming-Sheng Chen; Fei-Na Li; Xiao-Hui Chen; Xiao-Rui Yan; Li Tuo (Antonie van Leeuwenhoek, 2021)

Identification and integrated analysis of mRNAs, lncRNAs, and microRNAs of developing seeds in high oleic acid sunflower (Helianthus annuus L.) - Yan Liu; Fei Zhou; Xutang Huang; Wenjun Wang; Shuquan Zhang; Fujuan Feng (Acta Physiologiae Plantarum, 2021)

Ecological thresholds of phytoplankton community across environmental gradients in the harmful algal blooms-frequently-occurring, subtropical coastal waters, East China Sea - Ran Ye; Chunying Ge; Qiong Wang; Qing Xu; Guofeng Xu; Yongkang Yan; Mingli Qin; Yanhong Cai; Yuejun Fei (Acta Oceanologica Sinica, 2021)

Neuromodulation-Based Stem Cell Therapy in Brain Repair: Recent Advances and Future Perspectives - Ti-Fei Yuan; Yi Dong; Li Zhang; Jieyu Qi; Chun Yao; Yongjun Wang; Renjie Chai; Yan Liu; Kwok-Fai So (Neuroscience Bulletin, 2021)

Construction of an infectious full-length cDNA clone of potato aucuba mosaic virus - Buyang Chen; Qi Lin; Yueyan Yin; Liangliang Jiang; Fang Wang; Shuzhen Hu; Xinyang Wu; Fei Xu; Jiejun Peng; Hongying Zheng; Chengqi Yan; Xiaohan Mo; et al. (Archives of Virology, 2021)

Complete genome sequence of passiflora virus Y infecting passion fruit in China - Binghua Chen; Dali Wu; Hongying Zheng; Guangze Li; Yuhao Cao; Jianping Chen; Fei Yan; Xuemei Song; Lin Lin (Archives of Virology, 2021)

Study on characteristics of waterflooding in fractured reservoirs based on discrete fracture model - Fanle Meng; Junjian Li; Hanqiao Jiang; Lin Zhao; Linkai Li; Yan Qiao; Yu Zhou; Fei Xu (Arabian Journal of Geosciences, 2021)

Far-Field Impacts of a Super Typhoon on Upper Ocean Phytoplankton Dynamics - Guoqiang Qiu; Xiaogang Xing; Fei Chai; Xiao-Hai Yan; Zhiyu Liu; Haili Wang (Frontiers in Marine Science, 2021)
Super typhoon Rammasun (2014) traveled across the South China Sea on July 16–18. Its far-field impacts on phytoplankton dynamics in the upper ocean were documented by a Biogeochemical-Argo (BGC-Argo) float located 200 km to the left of its track. Both surface chlorophyll-a concentration (Chla) and particulate backscattering coefficient ( b bp ) were observed to increase substantially within two distinct stages. The initial increase occurred during the passage of the typhoon, and the subsequent increase happened 5 days after the typhoon. In contrast, depth-integrated Chla and b bp in the upper 150 m underwent negligible changes throughout the entire period. The key lies in the fact that surface phytoplankton increases in the far-field region resulted from the physically driven vertical redistribution of particles, rather than from biological alternations. The first increase was attributed to the typhoon-induced strong turbulence which deepened the surface mixed layer, and thus entrained subsurface particles to the surface; the second was due to the post-typhoon adiabatic quasi-geostrophic adjustment of the upper ocean that gradually raised the isopycnals (and thus subsurface particles). These results challenge the prevailing wisdom on typhoon impacts, and thus shed new lights on the nature of the upper ocean responses to typhoons from both physical and biological perspectives.

Evaluation of the efficacy and safety of hydroxychloroquine in comparison with chloroquine in moderate and severe patients with COVID-19 - Qiuyu Li; Cheng Cui; Fei Xu; Jianping Zhao; Nan Li; Haichao Li; Tianbing Wang; Hua Zhang; Na Liu; Yudong Wei; Xiaoye Niu; Yan Xu; et al. (Science China Life Sciences, 2021)

The role of microglia in chronic pain and depression: innocent bystander or culprit? - Nan Yin; Enshi Yan; Wenbin Duan; Changyuan Mao; Qin Fei; Chun Yang; Yimin Hu; Xiaolin Xu (Psychopharmacology, 2021)

Propofol-Induced Anesthesia Alters Corticocortical Functional Connectivity in the Human Brain: An EEG Source Space Analysis - Xue Zhao; Yubo Wang; Yun Zhang; Haidong Wang; Junchan Ren; Fei Yan; Dawei Song; Ruini Du; Qiang Wang; Liyu Huang (Neuroscience Bulletin, 2021)

Uremic toxin indoxyl sulfate promotes proinflammatory macrophage activation by regulation of β-catenin and YAP pathways - Ying Li; Jing Yan; Minjia Wang; Jing Lv; Fei Yan; Jin Chen (Journal of Molecular Histology, 2021)
Evidence has been shown that indoxyl sulfate (IS) could impair kidney and cardiac functions. Moreover, macrophage polarization played important roles in chronic kidney disease and cardiovascular disease. IS acts as a nephron-vascular toxin, whereas its effect on macrophage polarization during inflammation is still not fully elucidated. In this study, we aimed to investigate the effect of IS on macrophage polarization during lipopolysaccharide (LPS) challenge. THP-1 monocytes were incubated with phorbol 12-myristate-13-acetate (PMA) to differentiate into macrophages, and then incubated with LPS and IS for 24 h. ELISA was used to detect the levels of TNFα, IL-6, IL-1β in THP-1-derived macrophages. Western blot assay was used to detect the levels of arginase1 and iNOS in THP-1-derived macrophages. Percentages of HLA-DR-positive cells (M1 macrophages) and CD206-positive cells (M2 macrophages) were detected by flow cytometry. IS markedly increased the production of the pro-inflammatory factors TNFα, IL-6, IL-1β in LPS-stimulated THP-1-derived macrophages. In addition, IS induced M1 macrophage polarization in response to LPS, as evidenced by the increased expression of iNOS and the increased proportion of HLA-DR+ macrophages. Moreover, IS downregulated the level of β-catenin, and upregulated the level of YAP in LPS-stimulated macrophages. Activating β-catenin signaling or inhibiting YAP signaling suppressed the IS-induced inflammatory response in LPS-stimulated macrophages by inhibiting M1 polarization. IS induced M1 macrophage polarization in LPS-stimulated macrophages via inhibiting β-catenin and activating YAP signaling. In addition, this study provided evidences that activation of β-catenin or inhibition of YAP could alleviate IS-induced inflammatory response in LPS-stimulated macrophages. This finding may contribute to the understanding of immune dysfunction observed in chronic kidney disease and cardiovascular disease.

Chelativorans alearense sp. nov., A Novel Bacterial Species Isolated From Soil in Alear, China - Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Wei-Min Li; Zong-Jun Du; Qiang Li (Current Microbiology, 2021)

CYT387, a Novel JAK2 Inhibitor, Suppresses IL-13-Induced Epidermal Barrier Dysfunction Via miR-143 Targeting IL-13Rα1 and STAT3 - Yan Zu; Xiao-Fei Chen; Qiang Li; Shu-Ting Zhang (Biochemical Genetics, 2021)

The effects of land use changes on climate warming by source-sink theory - Shuang-shuang Hou; Li-fei Yu; Wei Yan; Shu-hong Gu; Xiao-ping Gu (Arabian Journal of Geosciences, 2021)

Nocardioides acrostichi sp. nov., a novel endophytic actinobacterium isolated from leaf of Acrostichum aureum - Xiao-Hui Chen; Fei Li; Fei-Na Li; Ming-Sheng Chen; Xiao-Rui Yan; Zi-Bang He; Shun-Lian Li; You-Lang Wu; Li Tuo (Antonie van Leeuwenhoek, 2021)

Simultaneous detection of multiple bacterial and viral aquatic pathogens using a fluorogenic loop‐mediated isothermal amplification‐based dual‐sample microfluidic chip - Qian‐Jin Zhou; Jian‐Fei Lu; Xiu‐Rong Su; Jing‐Lei Jin; Shang‐Yang Li; Yan Zhou; Lei Wang; Xin‐Bin Shao; Yao‐Hua Wang; Mao‐Cang Yan; Ming‐Yun Li; Jiong Chen (Journal of Fish Diseases, 2021)
Rapid and user‐friendly diagnostic tests are necessary for early diagnosis and immediate detection of diseases, particularly for on‐site screening of pathogenic microorganisms in aquaculture. In this study, we developed a dual‐sample microfluidic chip integrated with a real‐time fluorogenic loop‐mediated isothermal amplification assay (dual‐sample on‐chip LAMP) to simultaneously detect 10 pathogenic microorganisms, that is Aeromonas hydrophila , Edwardsiella tarda , Vibrio harveyi , V. alginolyticus , V. anguillarum , V. parahaemolyticus , V. vulnificus , infectious hypodermal and haematopoietic necrosis virus, infectious spleen and kidney necrosis virus, and white spot syndrome virus. This on‐chip LAMP provided a nearly automated protocol that can analyse two samples simultaneously, and the tests achieved limits of detection (LOD) ranging from 10 0 to 10 –1 pg/μl for genomic DNA of tested bacteria and 10 –4 to 10 –5 pg/μl for recombinant plasmid DNA of tested viruses, with run times averaging less than 30 min. The coefficient of variation for the time‐to‐positive value was less than 10%, reflecting a robust reproducibility. The clinical sensitivity and specificity were 93.52% and 85.53%, respectively, compared to conventional microbiological or clinical methods. The on‐chip LAMP assay provides an effective dual‐sample and multiple pathogen analysis, and thus would be applicable to on‐site detection and routine monitoring of multiple pathogens in aquaculture.

Unnatural trend of global land long‐term surface air temperature change - Yu Wang; Pengcheng Yan; Fei Ji; Shankai Tang; Liu Yang; Shujuan Hu; Guolin Feng (International Journal of Climatology, 2021)
In the context of global warming, determining to what extent natural variability and external forcing have an impact on climate change is crucial for formulating mitigation policies and adaptation plans. We quantifiably and effectively separate unnatural trends from the global land surface air temperature (SAT) changes during 1951–2015 by calculating the long‐term correlation exponent through detrended fluctuation analysis and applying mainly probability statistics methods. We provide effective discriminated evidence for whether the observed SAT change exceeds its natural internal variability. Furthermore, we search the range of SAT changes caused by unnatural trends, and identify their corresponding minimum contributions to warming relative trends in different regions. The unnatural warming of the mid‐ to high latitude inland areas of Eurasia and North America is basically high, and the warming responses to unnatural forcing are most intense in these areas. Compared to earlier detection, we find the minimum unnatural trend contributes more than 80% to the observed SAT change in North America, northern Greenland, eastern Africa, and the mid‐ to high latitudes of Eurasia. In addition, the temporal evolutions of unnatural trends in key areas are determined. In North Africa, Western Australia, the United States and Mexico, the unnatural impact became significant at the earliest. Meanwhile, the overall unnatural trend in North Africa is the most significant, followed by western Brazil, and grows most rapidly over time in the two key areas.

The Combined Effects of Increased pCO2 and Warming on a Coastal Phytoplankton Assemblage: From Species Composition to Sinking Rate - Yuanyuan Feng; Fei Chai; Mark L. Wells; Yan Liao; Pengfei Li; Ting Cai; Ting Zhao; Feixue Fu; David A. Hutchins (Frontiers in Marine Science, 2021)
In addition to ocean acidification, a significant recent warming trend in Chinese coastal waters has received much attention. However, studies of the combined effects of warming and acidification on natural coastal phytoplankton assemblages here are scarce. We conducted a continuous incubation experiment with a natural spring phytoplankton assemblage collected from the Bohai Sea near Tianjin. Experimental treatments used a full factorial combination of temperature (7 and 11°C) and pCO 2 (400 and 800 ppm) treatments. Results suggest that changes in pCO 2 and temperature had both individual and interactive effects on phytoplankton species composition and elemental stoichiometry. Warming mainly favored the accumulation of picoplankton and dinoflagellate biomass. Increased pCO 2 significantly increased particulate organic carbon to particulate organic phosphorus (C:P) and particulate organic carbon to biogenic silica (C:BSi) ratios, and decreased total diatom abundance; in the meanwhile, higher pCO 2 significantly increased the ratio of centric to pennate diatom abundance. Warming and increased pCO 2 both greatly decreased the proportion of diatoms to dinoflagellates. The highest chlorophyll a biomass was observed in the high pCO 2 , high temperature phytoplankton assemblage, which also had the slowest sinking rate of all treatments. Overall, there were significant interactive effects of increased pCO 2 and warming on dinoflagellate abundance, pennate diatom abundance, diatom vs. dinoflagellates ratio and the centric vs. pennate ratio. These findings suggest that future ocean acidification and warming trends may individually and cumulatively affect coastal biogeochemistry and carbon fluxes through shifts in phytoplankton species composition and sinking rates.

Unraveling Physiological and Metabolomic Responses Involved in Phlox subulata L. Tolerance to Drought Stress - Yan Xiong; Yanting Qu; Hui Han; Fei Chen; Li Li; Huanwei Tang; Daidi Che; Xing Zhang (Plant Molecular Biology Reporter, 2021)

Phytoremediation of Cadmium Contaminated Soil: Impacts on Morphological Traits, Proline Content and Stomata Parameters of Sweet Sorghum Seedlings - Xicun Dong; Yan Chang; Rong Zheng; Xueqiang Wang; Xia Yan; Xiao-Fei Ma (Bulletin of Environmental Contamination and Toxicology, 2021)

Complete genome sequence of a novel foveavirus isolated from Allium sativum L. in China - Qi Luo; Shuzhen Hu; Qi Lin; Fei Xu; Jiejun Peng; Hongying Zheng; Guanwei Wu; Shaofei Rao; Jianping Chen; Yuwen Lu; Fengling Guo; Fei Yan (Archives of Virology, 2021)

Chelativorans xinjiangense sp. nov., a novel bacterial species isolated from soil in Xinjiang, China - Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Wei-Min Li; Zong-Jun Du; Qiang Li (Archives of Microbiology, 2021)

Improvement and application of preprocessing technique for multitrace seismic impedance inversion - Zhong Fei-Yan; Zhou Lu; Dai Rong-Huo; Yin Cheng; Zhao Hu; Xu Liang-Jun (Applied Geophysics, 2021)

Antagonism of Protease-Activated Receptor 4 Protects Against Traumatic Brain Injury by Suppressing Neuroinflammation via Inhibition of Tab2/NF-κB Signaling - Jianing Luo; Xun Wu; Haixiao Liu; Wenxing Cui; Wei Guo; Kang Guo; Hao Guo; Kai Tao; Fei Li; Yingwu Shi; Dayun Feng; Hao Yan; et al. (Neuroscience Bulletin, 2021)

Effect of initial minimum principal stress and unloading rate on the spalling and rockburst of marble: a true triaxial experiment investigation - Quan Jiang; Meizhu Zhang; Fei Yan; Guoshao Su; Xiating Feng; Dingping Xu; Guangliang Feng (Bulletin of Engineering Geology and the Environment, 2021)

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study - Hao Wang; Xue Han; Mei Jin; Li-yan Wang; Zong-li Diao; Wang Guo; Peng Zhang; Zheng Wang; Han Lv; He-yu Ding; Zheng-yu Zhang; Peng-fei Zhao; et al. (Brain Imaging and Behavior, 2021)

NUIST ESM v3 Data Submission to CMIP6 - Jian Cao; Libin Ma; Fei Liu; Jing Chai; Haikun Zhao; Qiong He; Bo Wang; Yan Bao; Juan Li; Young-min Yang; Hua Deng; Bin Wang (Advances in Atmospheric Sciences, 2021)
This paper introduces the experimental designs and outputs of the Diagnostic, Evaluation and Characterization of Klima (DECK), historical, Scenario Model Intercomparison Project (MIP), and Paleoclimate MIP (PMIP) experiments from the Nanjing University of Information Science and Technology Earth System Model version 3 (NESM3). Results show that NESM3 reasonably simulates the modern climate and the major internal modes of climate variability. In the Scenario MIP experiment, changes in the projected surface air temperature (SAT) show robust “Northern Hemisphere (NH) warmer than Southern Hemisphere (SH)” and “land warmer than ocean” patterns, as well as an El Niño-like warming over the tropical Pacific. Changes in the projected precipitation exhibit “NH wetter than SH” and “eastern hemisphere gets wetter and western hemisphere gets drier” patterns over the tropics. These precipitation patterns are driven by circulation changes owing to the inhomogeneous warming patterns. Two PMIP experiments show enlarged seasonal cycles of SAT and precipitation over the NH due to the seasonal redistribution of solar radiation. Changes in the climatological mean SAT, precipitation, and ENSO amplitudes are consistent with the results from PMIP4 models. The NESM3 outputs are available on the Earth System Grid Federation nodes for data users.

Failure Performance of 3DP Physical Twin-Tunnel Model and Corresponding Safety Factor Evaluation - Quan Jiang; Xiaopei Liu; Fei Yan; Yao Yang; Dingping Xu; Guangliang Feng (Rock Mechanics and Rock Engineering, 2021)

A moso bamboo transcription factor, Phehdz1, positively regulates the drought stress response of transgenic rice - Yameng Gao; Huanlong Liu; Kaimei Zhang; Fei Li; Min Wu; Yan Xiang (Plant Cell Reports, 2021)

Amniotic fluid mesenchymal stem cells repair mouse corneal cold injury by promoting mRNA N4-acetylcytidine modification and ETV4/JUN/CCND2 signal axis activation - Xinfeng Fei; Yuying Cai; Feng Lin; Yongyi Huang; Te Liu; Yan Liu (Human Cell, 2021)
Severe corneal injury is one of the main causes of loss of visual function. Mesenchymal stem cells (MSCs) have the ability to repair damaged cells in vivo. The present study aimed to explore whether MSCs could function as a cell therapy tool to replace traditional methods to treat corneal injury. CD44 + /CD105 + mesenchymal stem cells isolated from mouse amniotic fluid (mAF-MSCs) were injected into mice after cryoinjury to induce corneal endothelial cell injury. Histopathological assays indicated that mAF-MSCs could promote the growth of corneal epithelial cells, reduce keratitis, and repair the corneal damage caused by low temperature. cDNA microarray analysis revealed that the mAF-MSCs affected the expression patterns of mRNAs related to cell proliferation and differentiation pathways in the mice after transplantation. The results of quantitative real-time PCR and western blotting revealed that NAT12, NAT10, and the ETV4/JUN/CCND2 signaling axis were elevated significantly in the mAF-MSC-transplantation group, compared with those in the phosphate-buffered saline-treated groups. High performance liquid chromatography–mass spectroscopy results revealed that mAF-MSCs could promote mRNA N4-acetylcytidine (ac4C) modification and high expression of N -acetyltransferase in the eyeballs. RNA immunoprecipitation-PCR results showed that a specific product comprising Vegfa , Klf4 , Ccnd2 , Jun , and Etv4 mRNA specific coding region sites could be amplified using PCR from complexes formed in mAF-MSC-transplanted samples cross-linked with anti-ac4C antibodies. Thus, mouse amniotic fluid MSCs could repair the mouse corneal cold injury by promoting the ETV4/JUN/CCND2 signal axis activation and improving its stability by stimulating N4-acetylcytidine modification of their mRNAs.

Income inequality and growth from functional orientation and spatial policy: Case study of Tibet, China - Yan-nan Zhao; Jie Fan; Ya-fei Wang; Bo Liang; Lu Zhang (Journal of Mountain Science, 2021)

Complete genome sequence of a new achyranthes virus A isolate from Achyranthes bidentata in China - Xinyang Wu; Yuchao Lai; Lanqing Lv; Kelei Han; Ziqiang Chen; Yuwen Lu; Jiejun Peng; Lin Lin; Jianping Chen; Hongying Zheng; Fei Yan (Archives of Virology, 2021)

A new cyclic peptide from the fibrous root of Pseudostellaria heterophylla - Xiao-fei Zhao; Qian Zhang; Han-tao Zhao; Yan-da Zhang; Han-ru Liu; Lu-jiang Yuan; Qian-feng Chen (Natural Product Research, 2020)

Association of in-hospital intensive statins dosage and death in arteriosclerotic cardiovascular disease with percutaneous coronary intervention: insights of multicentre cohort from China - Peng-yuan Chen; Yuan-hui Liu; Chong-yang Duan; Hua-lin Fan; Li-huan Zeng; Wei Guo; Lei Jiang; Xue-biao Wei; Wen-fei He; Sha Tao; Zhi-qiang Guo; Ji-yan Chen; et al. (European Journal of Clinical Pharmacology, 2020)

miR-217/Mafb Axis Involve in High Glucose-Induced β-TC-tet Cell Damage Via Regulating NF-κB Signaling Pathway - Huizhen Zheng; Xinying Li; Xinyu Yang; Fei Yan; Chuan Wang; Jinbo Liu (Biochemical Genetics, 2020)

Microplastics in the soil environment: Occurrence, risks, interactions and fate – A review - Baile Xu; Fei Liu; Zachary Cryder; Dan Huang; Zhijiang Lu; Yan He; Haizhen Wang; Zhenmei Lu; Philip C. Brookes; Caixian Tang; Jay Gan; Jianming Xu (Critical Reviews in Environmental Science and Technology, 2020)

Physiological and transcriptional response to heat stress in heat-resistant and heat-sensitive maize (Zea mays L.) inbred lines at seedling stage - De-Chuan Wu; Jia-Fei Zhu; Zhong-Ze Shu; Wei Wang; Cheng Yan; Shan-Bin Xu; De-Xiang Wu; Cheng-Yu Wang; Zhao-rong Dong; Genlou Sun (Protoplasma, 2020)

Illumina sequencing revealed roles of microRNAs in different aluminum tolerance of two citrus species - Yang-Fei Zhou; Yan-Yu Wang; Wei-Wei Chen; Li-Song Chen; Lin-Tong Yang (Physiology and Molecular Biology of Plants, 2020)

Evolution mechanism study of flow slide catastrophes in large waste dumps at the Nanfen iron mine - Hai-bin Wang; Fei Yan; Xiao-chun Li; Zi-jun Mi; Xiang-ming Li; Shao-quan Wang (Bulletin of Engineering Geology and the Environment, 2020)

Arthrobacter sedimenti sp. nov., isolated from river sediment in Yuantouzhu park, China - Pei Lin; Zheng-Fei Yan; Chang-Tian Li (Archives of Microbiology, 2020)

Incidence of antibiotic resistance in Vibrio spp - Ke‐Yan Loo; Vengadesh Letchumanan; Jodi Woan‐Fei Law; Priyia Pusparajah; Bey‐Hing Goh; Nurul‐Syakima Ab Mutalib; Ya‐Wen He; Learn‐Han Lee (Reviews in Aquaculture, 2020)
Vibrio species is a common natural inhabitant of brackish and saltwater. Vibrio sp. includes not only emerging pathogens but also well‐known and emerged pathogens, such as V. cholerae , V. parahaemolyticus and V. vulnificus . Although it is often harmless, pathogenic strains which could cause serious food‐borne illnesses/outbreaks in both humans and animals have been identified. Vibrio infection is usually self‐limiting and requires no clinical treatment. However, antibiotics are still required to treat severe cases of Vibrio infection. Recent reports have highlighted a rise in the presence of antibiotic‐resistant Vibrio in the environment. This hampers the clinical treatment of Vibrio infection and has been linked to the imprudent use of antibiotics in various fields such as human medicine, agriculture and animal husbandry. As a result, it has greatly jeopardized food security, threatened public health and impugned the growth of economy. Food is a potential vehicle of antibiotic‐resistant Vibrio where the resistant genes are transmitted to humans via ingestion of contaminated food. Hence, the surveillance, monitoring and management of antibiotic patterns of Vibrio are important for clinical treatment. This review focuses on different trends and global patterns of antibiotic resistance of Vibrio .

Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice - Qi Yang; Li Luo; Ting Sun; Le Yang; Li-Fei Cheng; Yan Wang; Qing-Qing Liu; An Liu; Hai-Yan Liu; Ming-Gao Zhao; Sheng-Xi Wu; Bin Feng (Psychopharmacology, 2020)

Molecularly Imprinted Polymers Doped with Carbon Nanotube with Aid of Metal-Organic Gel for Drug Delivery Systems - Long Zhao; Mei-Hong Chai; Hong-Fei Yao; Yan-Ping Huang; Zhao-Sheng Liu (Pharmaceutical Research, 2020)

Transcription Factors Phox2a/2b Upregulate Expression of Noradrenergic and Dopaminergic Phenotypes in Aged Rat Brains - Yan Fan; Fei Zeng; Russell W. Brown; Jennifer B. Price; Thomas C. Jones; Meng-Yang Zhu (Neurotoxicity Research, 2020)

Bufotalin ameliorates experimental Sjögren’s syndrome development by inhibiting Th17 generation - Yang Huang; Guangxia Yang; Jing Fei; Yingyi Wu; Juzhen Yan (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Verticillin A inhibits colon cancer cell migration and invasion by targeting c-Met - Qian-qian Liu; Xue-li Zeng; Yue-lin Guan; Jing-xin Lu; Kai Tu; Fei-yan Liu (Journal of Zhejiang University-SCIENCE B, 2020)

Novel environmental factors affecting microbial responses and physicochemical properties by sequentially applied biochar in black soil - Huanhuan Wang; Shen Yan; Tianbao Ren; Ye Yuan; Gang Kuang; Bo Wang; Fei Yun; Huilin Feng; Xiaoming Ji; Xiaojing Yuan; Guoshun Liu (Environmental Science and Pollution Research, 2020)

The blocking effect of the sand fences quantified using wind tunnel simulations - Yan-ping Yu; Ke-cun Zhang; Zhi-shan An; Tao Wang; Fei Hu (Journal of Mountain Science, 2020)

Elevated IL-22 in psoriasis plays an anti-apoptotic role in keratinocytes through mediating Bcl-xL/Bax - Bo Wang; Dan Han; Fei Li; Weikun Hou; Lijuan Wang; Liesu Meng; Kuanhou Mou; Shemin Lu; Wenhua Zhu; Yan Zhou (Apoptosis, 2020)
IL-22 is known to mediate inflammation in psoriasis, while IL-22 binding protein (IL-22BP) binds IL-22 to suppress IL-22 signaling. However, the function of IL-22 in regulating apoptosis in psoriasis remains poorly understood. In this study, we found that IL-22/IL-22R1 in lesional skin and IL-22 in serum from psoriatic patients were highly upregulated compared with healthy controls, while IL-22BP was not changed. Correlations between IL-22/IL-22R1 levels and the thickness of psoriatic lesions suggested that IL-22 might positively regulate abnormal hyperplasia in psoriasis. Apoptotic keratinocytes were increased only in stratum corneum, but not in spinous and basal layers of psoriasis. Moreover, IL-22 promoted cell viability in human epidermal keratinocytes (HEKs). The apoptosis induced by TNF-α and IFN-γ was inhibited in HEKs treated with IL-22, since that IL-22 upregulated Bcl-xL and downregulated Bax production in HEKs in the presence of TNF-α and IFN-γ. In addition, IL-22BP could counteract the anti-apoptotic effect of IL-22. Our finding demonstrates that IL-22 might play an anti-apoptosis role on keratinocytes to balance cell proliferation and apoptosis in psoriatic epidermis.

Immunocytochemical Localization of the Kinetochore Protein Nuf2p on the Gametophyte Chromosomes of a Cultivar of Saccharina (Phaeophyta) - Wu-Shan Dong; Peng-Fei Liu; Yu Liu; Yu Du; Yan-Hui Bi; Zhi-Gang Zhou (Frontiers in Marine Science, 2020)

RETRACTED ARTICLE: A New Luminescent Zn(II) Complex: Selective Sensing of Cr2O72− and Prevention Activity Against Orthodontic Root Absorption by Suppressing Inflammatory Response - Yan-Feng Zhu; Wei-Qun Guan; Fei Lin; Wei-Hui Chen (Journal of Fluorescence, 2020)

Degradation of the ciprofloxacin antibiotic by photo-Fenton reaction using a Nafion/iron membrane: role of hydroxyl radicals - Fei Wang; Yichen Zhang; Hao Ming; Li Wang; Zhongyuan Zhao; Yuehong Wang; Jiyan Liang; Yan Qin (Environmental Chemistry Letters, 2020)

Grouting rock fractures under condition of flowing water - Yan-xu Guo; Qing-song Zhang; Fei Xiao; Ren-tai Liu; Zhen-jun Wang; Yan-kai Liu (Carbonates and Evaporites, 2020)

Positive RT-PCR in urine from an asymptomatic patient with novel coronavirus 2019 infection: a case report - Jian-guo Ren; Dong-yan Li; Chang-fei Wang; Jian-hua Wu; Ying Wang; Yu-jing Sun; Qian Zhang; Yao-yong Wang; Xin-jian Chang (Infectious Diseases, 2020)

Patients with radiation enteritis present regulatory T cell impairment associated with CTLA-4 - Xufeng Gong; Genhua Yu; Zongchang Song; Shuqi Huang; Yan Hou; Ning Wang; Wei Zhao; Jingjing Ouyang; Zhengzhou Gu; Haili Hu; Lei Fei; Aixia Fu; et al. (Immunologic Research, 2020)

Salt tolerance and exclusion in the mangrove plant Avicennia marina in relation to root apoplastic barriers - Hao Cheng; Anifiok Inyang; Chang-Da Li; Jiao Fei; Yan-Wu Zhou; You-Shao Wang (Ecotoxicology, 2020)

Gastric smooth muscle cells manifest an abnormal phenotype in Parkinson’s disease rats with gastric dysmotility - Xiao-Lin Xiu; Li-Fei Zheng; Xiao-Yu Liu; Yan-Yan Fan; Jin-Xia Zhu (Cell and Tissue Research, 2020)

Global correlation analysis for miRNA and protein expression profiles in human peripheral blood mononuclear cells - Liang Huang; Fei-Yan Deng; Shu-Feng Lei (Molecular Biology Reports, 2020)

Luteimonas cellulosilyticus sp. nov., Cellulose-Degrading Bacterium Isolated from Soil in Changguangxi National Wetland Park, China - Pei Lin; Zheng-Fei Yan; Chang-Tian Li (Current Microbiology, 2020)

New insight into the molecular phylogeny of the genus Liparis s.l. (Orchidaceae: Malaxideae) with a new generic segregate: Blepharoglossum - Lin Li; Shih-Wen Chung; Bo Li; Song-Jun Zeng; Hai-Fei Yan; Shi-Jin Li (Plant Systematics and Evolution, 2020)
Molecular studies have shown that Liparis s.l. is polyphyletic, with the epiphytic Liparis alliance well separated from the clade representing Liparis in its restricted sense and further forming a phylogenetically heterogeneous assemblage. The generic status of Cestichis , as the key member of the epiphytic Liparis alliance, remains contentious, and the relationships between Cestichis , Stichorkis and Platystyliparis are still unclear and in need of further studies. We herein employ DNA sequence data from nuclear ITS and plastid mat K regions to clarify the generic boundaries of Cestichis and its relationship to the allied genera. Results from both Bayesian inference and maximum likelihood analysis congruently indicate that Cestichis as currently circumscribed is not monophyletic. The Blepharoglossum clade, corresponding to commonly recognized sect. Blepharoglossum , forms a monophyletic lineage closely related to the genus Oberonia instead of the core Cestichis clade. A re-evaluation of the diagnostic morphological characters reveals that this lineage represents a morphologically distinct group. Based on these results, Blepharoglossum is removed from Cestichis and elevated to generic status. Our study also sheds light on the homoplastic nature of some diagnostic morphological characters used traditionally in the taxonomy of the Malaxidinae.

SNX-2112, an Hsp90 inhibitor, suppresses cervical cancer cells proliferation, migration, and invasion by inhibiting the Akt/mTOR signaling pathway - Liang-Shun Fu; Hong-Hong Qiu; Min Liu; Liu-Bing Hu; Yan Wang; Peng-Chao Zhang; Man-Mei Li; Yi-Fei Wang; Zhong Liu (Medicinal Chemistry Research, 2020)

Synthesis and bioactivities of phenazine-1-carboxylic piperazine derivatives - Fei Han; Ru Yan; Min Zhang; Zhu Xiang; Qinglai Wu; Junkai Li (Natural Product Research, 2020)

Pictalignans D-F, three new neolignan derivatives from Selaginella picta - Fei Cheng; Zhen-Xing Zou; Ping-Sheng Xu; Shui-Han Zhang; Yan Zhang; Cai-Ping Yao; Kang-Ping Xu; Gui-Shan Tan (Natural Product Research, 2020)

NK cell reconstitution following unmanipulated HLA-mismatched/haploidentical transplantation compared with matched sibling transplantation - Li-Juan Hu; Xun-Hong Cao; Xing-Xing Yu; Xue-Fei Liu; Xiao-Su Zhao; Ying-Jun Chang; Xiao-Hui Zhang; Lan-Ping Xu; Yu Wang; Kai-Yan Liu; Xiao-Jun Huang; Xiang-Yu Zhao (Science China Life Sciences, 2020)

Photosynthetic acclimation of rhododendrons to light intensity in relation to leaf water-related traits - Ji-Hua Wang; Yan-Fei Cai; Shi-Feng Li; Shi-Bao Zhang (Plant Ecology, 2020)

First report of leaf spot on Amorphophallus muelleri caused by Colletotrichum gloeosporioides in Yunnan, China - Min Yang; Huan-yu Wei; Fei-yan Huang; Wei-hua Pei; Jia-ni Liu; Yu Zhong; Wei Wei; Wen-ting Hu; Lei Yu (Journal of Plant Pathology, 2020)

First report of actinidia virus A and B infecting kiwifruit in Jiangxi province in China - Man Fei Zou; Ming Feng Yan; Ying Zhou; Yuan Xiu Wang; Gui Hong Xiong; Jun Xi Jiang (Journal of Plant Pathology, 2020)

Leukocyte immunoglobulin-like receptor B4 protects against cardiac hypertrophy via SHP-2-dependent inhibition of the NF-κB pathway - Heng Zhou; Ning Li; Yuan Yuan; Ya-Ge Jin; Qingqing Wu; Ling Yan; Zhou-Yan Bian; Wei Deng; Di-Fei Shen; Hongliang Li; Qi-Zhu Tang (Journal of Molecular Medicine, 2020)

Stratospheric Ozone-induced Cloud Radiative Effects on Antarctic Sea Ice - Yan Xia; Yongyun Hu; Jiping Liu; Yi Huang; Fei Xie; Jintai Lin (Advances in Atmospheric Sciences, 2020)
Recent studies demonstrate that the Antarctic Ozone Hole has important influences on Antarctic sea ice. While most of these works have focused on effects associated with atmospheric and oceanic dynamic processes caused by stratospheric ozone changes, here we show that stratospheric ozone-induced cloud radiative effects also play important roles in causing changes in Antarctic sea ice. Our simulations demonstrate that the recovery of the Antarctic Ozone Hole causes decreases in clouds over Southern Hemisphere (SH) high latitudes and increases in clouds over the SH extratropics. The decrease in clouds leads to a reduction in downward infrared radiation, especially in austral autumn. This results in cooling of the Southern Ocean surface and increasing Antarctic sea ice. Surface cooling also involves ice-albedo feedback. Increasing sea ice reflects solar radiation and causes further cooling and more increases in Antarctic sea ice.

Seasonal Variation of Lipid Profile of Oyster Crassostrea talienwhanensis from the Yellow Sea Area - Yan-Fei Liu; Zi-Xuan Wu; Jing Zhang; Yu-Xin Liu; Zhong-Yuan Liu; Hong-Kai Xie; Kanyasiri Rakariyatham; Da-Yong Zhou (Journal of Aquatic Food Product Technology, 2020)

Purification and characterization of two grandiuvarones from Desmos chinensis leaves and their antimicrobial activities - Qing-Qing Zhi; Quan-Hong Yan; Qiong Wang; Peng-Fei Sun; Hai-Yun Zhou; Zhu-Mei He (Natural Product Research, 2020)

Endometrial autophagy is essential for embryo implantation during early pregnancy - Yan Su; Juan-Juan Zhang; Jun-Lin He; Xue-Qing Liu; Xue-Mei Chen; Yu-Bin Ding; Chao Tong; Chuan Peng; Yan-Qing Geng; Ying-Xiong Wang; Ru-Fei Gao (Journal of Molecular Medicine, 2020)

Late Carboniferous mafic to felsic intrusive rocks in the central Great Xing’an Range, NE China: petrogenesis and tectonic implications - Yong-Fei Ma; Yong-Jiang Liu; Yan Wang; Tao Qin; Huijun Chen; Wei Sun; Yanqing Zang (International Journal of Earth Sciences, 2020)

Human umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease by inhibiting ERK phosphorylation in neutrophils - Gaoying Wang; Mbobda Defo Marius Joel; Jintao Yuan; Jingyan Wang; Xiu Cai; Dickson Kofi Wiredu Ocansey; Yongmin Yan; Hui Qian; Xu Zhang; Wenrong Xu; Fei Mao (Inflammopharmacology, 2020)

Tracing solute sources and carbon dynamics under various hydrological conditions in a karst river in southwestern China - Jing Liu; Bo Chen; Zhu-Yan Xu; Yuan Wei; Zhi-Hua Su; Rui Yang; Yong-Xue Ji; Xiao-Dan Wang; Li-Li Zhang; Ning An; Fei Yang (Environmental Science and Pollution Research, 2020)

Interannual Variability and Scenarios Projection of Sea Ice in Bohai Sea Part I: Variation Characteristics and Interannual Hindcast - Yan Jiao; Fei Huang; Qingrong Liu; Ge Li; Yaru Li; Qingxi Yu; Yiding Zhao (Journal of Ocean University of China, 2020)

The Arabidopsis UDP-glycosyltransferase75B1, conjugates abscisic acid and affects plant response to abiotic stresses - Ting-Ting Chen; Fang-Fei Liu; Dong-Wang Xiao; Xiao-Yi Jiang; Pan Li; Shu-Man Zhao; Bing-kai Hou; Yan-jie Li (Plant Molecular Biology, 2020)

Characterization of two novel Alu element-mediated α-globin gene cluster deletions causing α0-thalassemia by targeted next-generation sequencing - Zhiming Li; Xuan Shang; Shiqiang Luo; Fei Zhu; Xiaofeng Wei; Wanjun Zhou; Yuhua Ye; Tizhen Yan; Ren Cai; Xiangmin Xu (Molecular Genetics and Genomics, 2020)

Two novel strains, Bacillus albus JK-XZ3 and B. velezensis JK-XZ8, with activity against Cerasus crown gall disease in Xuzhou, China - Peng Yan; Xi-Tang Zhang; Long-Jiao Hu; Ya-Hui Wang; Mei-Ling Zhu; Xiao-Qin Wu; Fei Chen (Australasian Plant Pathology, 2020)

(±)-Quassidine K, a pair of cytotoxic bis- β -carboline alkaloid enantiomers from Picrasma quassioides - Xin-Ming Guo; Fei Li; Fang-Fang Zheng; Na-Na Gong; Yan Li; Wen-Zhou Feng; Lin Tian (Natural Product Research, 2020)

Application of metagenomic next-generation sequencing for bronchoalveolar lavage diagnostics in critically ill patients - Ying Li; Bing Sun; Xiao Tang; Ya-lan Liu; Hang-yong He; Xu-yan Li; Rui Wang; Fei Guo; Zhao-hui Tong (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Southern-Hemisphere high-latitude stratospheric warming revisit - Yan Xia; Weixuan Xu; Yongyun Hu; Fei Xie (Climate Dynamics, 2020)
Previous studies showed significant stratospheric warming at the Southern-Hemisphere (SH) high latitudes in September and October over 1979–2006. The warming trend center was located over the Southern Ocean poleward of the Western Pacific in September, with a maximum trend of about 2.8 K/decade. The warming trends in October showed a dipole pattern, with the warming center over the Ross and Amundsen Sea, and the maximum warming trend is about 2.6 K/decade. In the present study, we revisit the problem of the SH stratospheric warming in the recent decade. It is found that the SH high-latitude stratosphere continued warming in September and October over 2007–2017, but with very different spatial patterns. Multiple linear regression demonstrates that ozone increases play an important role in the SH high-latitude stratospheric warming in September and November, while the changes in the Brewer-Dobson circulation contributes little to the warming. This is different from the situation over 1979–2006 when the SH high-latitude stratospheric warming was mainly caused by the strengthening of the Brewer-Dobson circulation and the eastward shift of the warming center. Simulations forced with observed ozone changes over 2007–2017 shows warming trends, suggesting that the observed warming trends over 2007–2017 are at least partly due to ozone recovery. The warming trends due to ozone recovery have important implications for stratospheric, tropospheric and surface climates on SH.

Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression - Fang Yang; Wang-wang Liu; Hui Chen; Jia Zhu; Ai-hua Huang; Fei Zhou; Yi Gan; Yan-hua Zhang; Li Ma (Journal of Zhejiang University-SCIENCE B, 2020)

Preparation and In vitro Evaluation of FDM 3D-Printed Ellipsoid-Shaped Gastric Floating Tablets with Low Infill Percentages - Di Chen; Xiang-Yu Xu; Rui Li; Gen-Ao Zang; Yue Zhang; Ming-Rui Wang; Meng-Fei Xiong; Jia-Rui Xu; Ting Wang; Hui Fu; Qin Hu; Bin Wu; et al. (AAPS PharmSciTech, 2020)

Metabolomic profiling on rat brain of prenatal malnutrition: implicated for oxidative stress and schizophrenia - Fei Xu; Xin Li; Weibo Niu; Gaini Ma; Qianqian Sun; Yan Bi; Zhenming Guo; Decheng Ren; Jiaxin Hu; Fan Yuan; Ruixue Yuan; Lei Shi; et al. (Metabolic Brain Disease, 2019)

Age- and Nicotine-Associated Gene Expression Changes in the Hippocampus of APP/PS1 Mice - Jie Yang; Yan Long; De-Mei Xu; Bing-Lin Zhu; Xiao-Juan Deng; Zhen Yan; Fei Sun; Guo-Jun Chen (Journal of Molecular Neuroscience, 2019)

Paeoniflorin inhibits Th1 and Th17 cells in gut-associated lymphoid tissues to produce anti-arthritis activities - Fei Fei; Li-xiang Aa; Qi Qi; Run-bin Sun; Cai-xia Yan; Ji-ye Aa; Guang-ji Wang (Inflammopharmacology, 2019)

Chronology of coastal aeolian deposition and its paleoenvironmental implications on the Liuao Peninsula of South China - Jian-hui Jin; Zhi-zhong Li; Zhi-yong Ling; Fei Zheng; Xiao-lin Xu; Yan Cheng; Xiang-dong Cao; Zhi-xing Li; Wen-jing Zhang; Yong-qing Ren (Journal of Mountain Science, 2019)

Experiment and Discrete Element Modelling on Strength, Deformation and Failure Behaviour of Shale Under Brazilian Compression - Sheng-Qi Yang; Peng-Fei Yin; Yan-Hua Huang (Rock Mechanics and Rock Engineering, 2019)

Engineering properties of loess stabilized by a type of eco-material, calcium lignosulfonate - Guo-yu Li; Xin Hou; Yan-hu Mu; Wei Ma; Fei Wang; Yu Zhou; Yun-cheng Mao (Arabian Journal of Geosciences, 2019)

Cellulomonas aurantiaca sp. nov., isolated from a soil sample from a tangerine field - Su-Kyung Kim; MooChang Kook; Zheng-Fei Yan; Huan Trinh; Sheng-Dao Zheng; Jung-Eun Yang; Sang-Yong Park; Tae-Hoo Yi (Antonie van Leeuwenhoek, 2019)

Synthesis of natural product inulavosin via Ga(OTf) 3 -Catalyzed Hetero Diels–Alder Dimerization of salicyl alcohol derivative - Pi-Xian Gong; Hui-Jing Li; Meirong Wang; Yun-Fei Cheng; Yan-Chao Wu (Natural Product Research, 2019)

The effects of landscape scale on greenery and traffic relationships with urban birds and butterflies - Kwek Yan Chong; Siyang Teo; Buddhima Kurukulasuriya; Yi Fei Chung; Xingli Giam; Hugh T. W. Tan (Urban Ecosystems, 2019)

Optically stimulated luminescence ages of the Hengyu site and their implications for anthropogenic activities in the Fuzhou Basin, South China - Jianhui Jin; Yunming Huang; Yong Zhang; Zhizhong Li; Xuechun Fan; Zhiyong Ling; Fei Zheng; Yan Cheng; Xiaolin Xu; Zhixing Li; Wenjing Zhang (Journal of Quaternary Science, 2019)
The chronologies of few Neolithic sites in the lower reaches of the Min River of China have been well investigated for the middle to late Holocene. In this study, the Hengyu Neolithic site in Fujian Province, South China, which has significant archaeological remains, was dated using blue‐stimulated optically stimulated luminescence (OSL) and accelerator mass spectrometry radiocarbon (AMS 14 C) techniques. The results, comprising nine OSL and three AMS 14 C ages through the Neolithic sequence, provide new evidence towards understanding the relationship between environmental evolution and human activities in the middle to late Holocene in the Fuzhou Basin and coastal areas of South China. The ages of the site deposits vary from 6.83 to 1.67 ka and can be divided into two main phases: the Keqiutou–Tanshishan culture period and the Bronze culture period. In contrast, the persistent periods of ancient human activities at the Hengyu site seem to correspond to regional sea‐level changes and the East Asian winter monsoon as a secondary factor, which can affect human activities through sea‐level impacts. The warm and high sea level conditions provided a liveable environment for the ancient humans of Fujian and even South China. The ages of two building column bases are linked to the early stage of the Han dynasty, suggesting a potentially favourable habitation environment; that is, ancient humans occupied and settled this area for the long term within this time period, which is consistent with sea‐level changes and palynology records. Copyright © 2019 John Wiley & Sons, Ltd.

Zircon U–Pb geochronology and Hf isotopic constraints on the petrogenesis of the Late Silurian Shidonggou granite from the Wulonggou area in the Eastern Kunlun Orogen, Northwest China - Qing-Feng Ding; Kai Song; Qiang Zhang; Wei Yan; Fei Liu (International Geology Review, 2019)

Pathogenicity of an FAdV-4 isolate to chickens and its genomic analysis - Kai-kun Mo; Chen-fei Lyu; Shang-shang Cao; Xia Li; Gang Xing; Yan Yan; Xiao-juan Zheng; Min Liao; Ji-yong Zhou (Journal of Zhejiang University-SCIENCE B, 2019)

Complete chloroplast genome of the threatened Rhoiptelea chiliantha (Juglandaceae s.l.) - Yan-Fei Geng; Guo-Xiong Hu; Shuo Wang; Jian-Chu Xu (Conservation Genetics Resources, 2019)

Detection and characterization of a novel hepacivirus in long-tailed ground squirrels (Spermophilus undulatus) in China - Li-li Li; Meng-meng Liu; Shu Shen; Yu-jiang Zhang; Ya-long Xu; Hong-yan Deng; Fei Deng; Zhao-jun Duan (Archives of Virology, 2019)

Inverse Gaussian-beam common-reflection-point-stack imaging in crosswell seismic tomography - Zheng Rong Wei; Fei-Long Yang; Bao-Hua Liu; Yan-Liang Pei (Applied Geophysics, 2019)

Scutellarein from Scutellaria barbata induces apoptosis of human colon cancer HCT116 cells through the ROS-mediated mitochondria-dependent pathway - Fei Guo; Feng Yang; Yan-Hong Zhu (Natural Product Research, 2019)

RETRACTED ARTICLE: Cancer-derived exosomal miR-221-3p promotes angiogenesis by targeting THBS2 in cervical squamous cell carcinoma - Xiang-Guang Wu; Chen-Fei Zhou; Yan-Mei Zhang; Rui-Ming Yan; Wen-Fei Wei; Xiao-Jing Chen; Hong-Yan Yi; Luo-Jiao Liang; Liang-sheng Fan; Li Liang; Sha Wu; Wei Wang (Angiogenesis, 2019)

De novo transcriptome analysis of Fraxinus velutina Torr in response to NaCl stress - Liping Yan; Cuilan Liu; Yinhua Wang; Kaifang Wang; Fei Ren; Junxiu Yao; Dejun Wu (Tree Genetics & Genomes, 2019)

Acyl-CoA synthetases from Physcomitrella, rice and Arabidopsis: different substrate preferences but common regulation by MS188 in sporopollenin synthesis - Yue-Ling Li; Yan-Fei Zhang; Dan-Dan Li; Qiang-Sheng Shi; Yue Lou; Zhong-Nan Yang; Jun Zhu (Planta, 2019)

Development Status and Prospects of Mine Physical Similar Material Simulation Experiments - Wen-bin Sun; Fei Zhou; Jian-li Shao; Hou-qian Du; Yan-chao Xue (Geotechnical and Geological Engineering, 2019)

GM1 Ameliorates Lead-Induced Cognitive Deficits and Brain Damage Through Activating the SIRT1/CREB/BDNF Pathway in the Developing Male Rat Hippocampus - Fei Chen; Can-Can Zhou; Yin Yang; Jian-Wen Liu; Chong-Huai Yan (Biological Trace Element Research, 2019)

Chitinophaga aurantiaca sp. nov., isolated from a soil sample from a tangerine field - Su-Kyung Kim; MooChang Kook; Zheng-Fei Yan; Sang-Yong Park; Sang Suk Kim; Ho Bin Kim; Huan Trinh; Kyung Hwa Won; Jung-Eun Yang; Tae-Hoo Yi (Antonie van Leeuwenhoek, 2019)

Bacterial community pattern along the sediment seafloor of the Arctic fjorden (Kongsfjorden, Svalbard) - Xiao-Mei Fang; Tao Zhang; Jun Li; Neng-Fei Wang; Zhen Wang; Li-Yan Yu (Antonie van Leeuwenhoek, 2019)

Dynamic expressions of hypothalamic genes regulate seasonal breeding in a natural rodent population - Dawei Wang; Ning Li; Lin Tian; Fei Ren; Zhengguang Li; Yan Chen; Lan Liu; Xiangfa Hu; Xuechang Zhang; Ying Song; Roelof A. Hut; Xiao‐Hui Liu (Molecular Ecology, 2019)
Seasonal breeding is a universal reproductive strategy in many animals. Hypothalamic genes, especially type 2 and 3 iodothyronine deiodinases ( Dio2 / 3 ), RFamide‐related peptide 3 ( Rfrp‐3 ), kisspeptin ( Kiss‐1 ) and gonadotropin‐releasing hormone ( GnRH ), are involved in a photoperiodic pathway that encodes seasonal signals from day length in many vertebrate species. However, the seasonal expression patterns of these genes in wild mammals are less studied. Here, we present a four‐year field investigation to reveal seasonal rhythm and age‐dependent reproductive activity in male Brandt's voles ( Lasiopodomys brandtii ) and to detect relationships among seasonal expression profiles of hypothalamic genes, testicular activity, age and annual day length. From breeding season (April) to nonbreeding season (October), adult male voles displayed a synchronous peak in gonadal activity with annual day length around summer solstice, which was jointly caused by age structure shifts and age‐dependent gonadal development patterns. Overwintered males maintained reproductive activity until late in the breeding season, whereas most newborn males terminated gonadal development completely, except for a minority of males born early in spring. Consistently, the synchronous and opposite expression profiles of Dio2/3 suggest their central function to decode photoperiodic signals and to predict the onset of the nonbreeding season. Moreover, changes in Dio2/3 signals may guide the actions of Kiss‐1 and Rfrp‐3 to regulate the age‐dependent divergence of reproductive strategy in wild Brandt's vole. Our results provide evidence on how hypothalamic photoperiod genes regulate seasonal breeding in a natural rodent population.

New adenine analogues and a pyrrole alkaloid from Selaginella delicatula - Cai-Ping Yao; Zhen-Xing Zou; Yan Zhang; Jing Li; Fei Cheng; Ping-Sheng Xu; Gan Zhou; Xiao-Min Li; Kang-Ping Xu; Gui-Shan Tan (Natural Product Research, 2019)

Regioselective synthesis of gentisyl alcohol-type marine natural products - Hong-Shuang Wang; Hui-Jing Li; Long-Fei Wang; Zhi-Lun Shen; Yan-Chao Wu (Natural Product Research, 2019)

Effects of frequency and confining pressure on consolidation drainage behavior of soft marine clays - Yong-Hong Miao; Fan-Bo Zhou; Jie Yin; Yan-Chang Sun; Rui-Bing Li; Jian-Fei Lu (Marine Georesources & Geotechnology, 2019)

Sustainable Design of Urban Stormwater Drainage Systems by Implementing Detention Tank and LID Measures for Flooding Risk Control and Water Quality Management - Fei Li; Xu-Feng Yan; Huan-Feng Duan (Water Resources Management, 2019)

Effect of High Temperature on Deformation Failure Behavior of Granite Specimen Containing a Single Fissure Under Uniaxial Compression - Sheng-Qi Yang; Yan-Hua Huang; Wen-Ling Tian; Peng-Fei Yin; Hong-Wen Jing (Rock Mechanics and Rock Engineering, 2019)

Physiological and transcriptomic analysis highlight key metabolic pathways in relation to drought tolerance in Rhododendron delavayi - Yan-Fei Cai; Ji-Hua Wang; Lu Zhang; Jie Song; Lv-Chun Peng; Shi-Bao Zhang (Physiology and Molecular Biology of Plants, 2019)

Inhibitor of ghrelin receptor reverses gefitinib resistance in lung cancer - Xiaoyou Li; Xia Zhao; Chenchen Li; Siwen Liu; Fei Yan; Yue Teng; Jifeng Feng; Dengshun Miao (Human Cell, 2019)

Evaluation of the association between urinary cadmium levels below threshold limits and the risk of diabetes mellitus: a dose-response meta-analysis - Fei-Fei Guo; Zhi-Yong Hu; Bing-Yan Li; Li-Qiang Qin; Chunling Fu; Huifang Yu; Zeng-Li Zhang (Environmental Science and Pollution Research, 2019)

Application of Avaatech X-ray fluorescence core-scanning in Sr/Ca analysis of speleothems - Dong Li; Liangcheng Tan; Fei Guo; Yanjun Cai; Youbin Sun; Gang Xue; Xing Cheng; Hong Yan; Hai Cheng; R. Lawrence Edwards; Yongli Gao; Jessica Kelley (Science China Earth Sciences, 2019)

SAMD9 is a (epi-) genetically regulated anti-inflammatory factor activated in RA patients - Pei He; Long-Fei Wu; Peng-Fei Bing; Wei Xia; Lan Wang; Fang-Fei Xie; Xin Lu; Shu-Feng Lei; Fei-Yan Deng (Molecular and Cellular Biochemistry, 2019)

Biodiesel production from Chlorella vulgaris under nitrogen starvation in autotrophic, heterotrophic, and mixotrophic cultures - Xiao-Fei Shen; Qi-Wen Qin; Shao-Kai Yan; Jia-Le Huang; Kun Liu; Shou-Biao Zhou (Journal of Applied Phycology, 2019)

Evolution Characteristics of Government-Industry-University Cooperative Innovation Network of Electronic Information Industry in Liaoning Province, China - Fei Peng; Qiqi Zhang; Zenglin Han; Yan Ding; Ningning Fu (Chinese Geographical Science, 2019)

Eremophilane sesquiterpenes from the endophytic fungus Xylaria sp. GDG-102 - Yan Liang; Weifeng Xu; Chengmei Liu; Dexiong Zhou; Xiaobo Liu; Yuyue Qin; Fei Cao; Jun Li; Ruiyun Yang; Jiangke Qin (Natural Product Research, 2019)

Novel hepacivirus in Asian house shrew, China - Hua Guo; Chunlin Cai; Bo Wang; Fei Zhuo; Rendi Jiang; Ning Wang; Bei Li; Wei Zhang; Yan Zhu; Yi Fan; Wushen Chen; Weihong Chen; et al. (Science China Life Sciences, 2019)

Characterization of Glycerophospholipid Molecular Species in Two Species of Arcidaes ( Scapharca subcrenata and Scapharca broughtonii ) - Yan-Fei Liu; Fa-Wen Yin; Yu-Xin Liu; Zi-Xuan Wu; Jing Zhang; Qi Zhao; Kanyasiri Rakariyatham; Da-Yong Zhou (Journal of Aquatic Food Product Technology, 2019)

Stability Analysis of Near-Wellbore Reservoirs Considering the Damage of Hydrate-Bearing Sediments - Xiaoling Zhang; Fei Xia; Chengshun Xu; Yan Han (Journal of Marine Science and Engineering, 2019)
The stability of hydrate-bearing near-wellbore reservoirs is one of the key issues in gas hydrate exploitation. In most previous investigations, the damage evolution process of the sediment structure and its effect on near-wellbore reservoir stability have been neglected. Therefore, the damage variable is introduced into a multi-field coupled model based on continuous damage theory and multi-field coupling theory. A thermo-hydro-mechanical-chemical (THMC) multi-field coupling mathematical model considering damage of hydrate-bearing sediments is established. The effects of damage of hydrate-bearing sediments on the thermal field, seepage field, and mechanical field are considered. Finally, the distributions of hydrate saturation, pore pressure, damage variable, and effective stress of a near-wellbore reservoir in gas hydrate exploitation by depressurization are calculated, and the stability of a hydrate-bearing near-wellbore reservoir is analyzed using the model. Through calculation and analysis, it is found that structural damage of hydrate-bearing sediments has an adverse effect on the stability of hydrate-bearing near-wellbore reservoirs. The closer to the wellbore, the worse the reservoir stability, and the near-wellbore reservoir stability is the worst in the direction of minimum horizontal ground stress.

Inhalation cancer risk estimation of source-specific personal exposure for particulate matter–bound polycyclic aromatic hydrocarbons based on positive matrix factorization - Bin Han; Yan You; Yating Liu; Jia Xu; Jian Zhou; Jiefeng Zhang; Can Niu; Nan Zhang; Fei He; Xiao Ding; Zhipeng Bai (Environmental Science and Pollution Research, 2019)

Triticum aestivum heat shock protein 23.6 interacts with the coat protein of wheat yellow mosaic virus - Shanshan Jiang; Bin Wu; Liangliang Jiang; Mei Zhang; Yuwen Lu; Shengji Wang; Fei Yan; Xiangqi Xin (Virus Genes, 2019)

Mucilaginibacter xinganensis sp. nov., a phenanthrene-degrading bacterium isolated from wetland soil - Min-zhi Jiang; Zhi-jun Qiu; Guang-wu Zhang; Shi-yin Gao; Xiao-yan You; Ying-fei Ma (Antonie van Leeuwenhoek, 2019)

Chemical constituents from the fruits of Psoralea corylifolia and their protective effects on ionising radiation injury - Jie Du; Chun-Hua Wang; Jing Yang; Xin He; Xiao-Liang Han; Cong-Cong Li; Xin Chai; Yue-Fei Wang; Yan Zhu; Zheng Li (Natural Product Research, 2019)

FLOURY ENDOSPERM15 encodes a glyoxalase I involved in compound granule formation and starch synthesis in rice endosperm - Xiaoman You; Wenwei Zhang; Jinlong Hu; Ruonan Jing; Yue Cai; Zhiming Feng; Fei Kong; Jie Zhang; Haigang Yan; Weiwei Chen; Xingang Chen; Jing Ma; et al. (Plant Cell Reports, 2019)

Geochronology, petrogenesis, and tectonic implications of Permian felsic rocks of the Central Great Xing’an Range, NE China - Yong-Fei Ma; Yong-Jiang Liu; Yan Wang; Cheng Qian; Qiu-Liang Si; Zhen Tang; Tao Qin (International Journal of Earth Sciences, 2019)

Detection of lncRNA-mRNA interaction modules by integrating eQTL with weighted gene co-expression network analysis - Xing-Bo Mo; Long-Fei Wu; Xin Lu; Xiao-Wei Zhu; Wei Xia; Lan Wang; Pei He; Peng-Fei Bing; Yong-Hong Zhang; Fei-Yan Deng; Shu-Feng Lei (Functional & Integrative Genomics, 2019)

Endophytic bacterial communities of Jingbai Pear trees in north China analyzed with Illumina sequencing of 16S rDNA - Fei Ren; Wei Dong; Dong-Hui Yan (Archives of Microbiology, 2019)

Evaluation of the zenithal total delay estimates from BeiDou/GPS combined signals in the frame of the IGS MGEX project - Peng Feng; Fei Li; Jianguo Yan; J.-P. Barriot (Acta Geodaetica et Geophysica, 2019)

Epigenetic Effects of Essential Fatty Acids - Andy T. Y. Lau; Fei-Yuan Yu; Yan-Ming Xu (Current Pharmacology Reports, 2019)

Iron Accumulation Leads to Bone Loss by Inducing Mesenchymal Stem Cell Apoptosis Through the Activation of Caspase3 - Ye Yuan; Fei Xu; Yan Cao; Li Xu; Chen Yu; Fan Yang; Peng Zhang; Liang Wang; Guangsi Shen; Jianrong Wang; Youjia Xu (Biological Trace Element Research, 2019)

Permafrost warming along the Mo’he-Jiagedaqi section of the China-Russia crude oil pipeline - Fei Wang; Guo-yu Li; Wei Ma; Yun-cheng Mao; Yan-hu Mu; Mihaela Serban; Yong-jun Cai (Journal of Mountain Science, 2019)

Isolation and functional identification of an apple MdCER1 gene - Chen-Hui Qi; Xian-Yan Zhao; Han Jiang; Peng-Fei Zheng; Hai-Tao Liu; Yuan-Yuan Li; Yu-Jin Hao (Plant Cell, Tissue and Organ Culture (PCTOC), 2019)

Interferon-γ regulates cell malignant growth via the c-Abl/HDAC2 signaling pathway in mammary epithelial cells - Wen-bo Ren; Xiao-jing Xia; Jing Huang; Wen-fei Guo; Yan-yi Che; Ting-hao Huang; Lian-cheng Lei (Journal of Zhejiang University-SCIENCE B, 2019)

Inhibition of YAP with siRNA prevents cartilage degradation and ameliorates osteoarthritis development - Yong Gong; Song-Jian Li; Rui Liu; Jian-Feng Zhan; Chao Tan; Yi-Fei Fang; Yan Chen; Bo Yu (Journal of Molecular Medicine, 2019)

Efficiency of sequential UV/H2O2 and biofilm process for the treatment of secondary effluent - Peng-Fei Yan; Shoujun Yuan; Wei Wang; Zhen-Hu Hu; Yang Mu; Han-Qing Yu (Environmental Science and Pollution Research, 2019)

Reduced hsa-miR-124-3p levels are associated with the poor survival of patients with hepatocellular carcinoma - Hui-Deng Long; Yu-Shui Ma; Hui-Qiong Yang; Shao-Bo Xue; Ji-Bin Liu; Fei Yu; Zhong-Wei Lv; Ji-Yu Li; Ru-Ting Xie; Zheng-Yan Chang; Gai-Xia Lu; Wen-Ting Xie; et al. (Molecular Biology Reports, 2018)

LaMIR166a-mediated auxin biosynthesis and signalling affect somatic embryogenesis in Larix leptolepis - Zhe-Xin Li; Yan-Ru Fan; Shao-Fei Dang; Wan-Feng Li; Li-Wang Qi; Su-ying Han (Molecular Genetics and Genomics, 2018)

EGb761 improves the cognitive function of elderly db/db−/− diabetic mice by regulating the beclin-1 and NF-κB signaling pathways - Zhu-Fei Guan; Xiao-Ming Zhang; Ying-Hong Tao; Yu Zhang; Yan-Yan Huang; Gang Chen; Wei-Jun Tang; Gang Ji; Qi-Lin Guo; Ming Liu; Qian Zhang; Na-Na Wang; et al. (Metabolic Brain Disease, 2018)

Interhemispheric functional connectivity for Alzheimer’s disease and amnestic mild cognitive impairment based on the triple network model - Zheng-luan Liao; Yun-fei Tan; Ya-ju Qiu; Jun-peng Zhu; Yan Chen; Si-si Lin; Ming-hao Wu; Yan-ping Mao; Jiao-jiao Hu; Zhong-xiang Ding; En-yan Yu (Journal of Zhejiang University-SCIENCE B, 2018)

Down-regulation of microRNA-216a confers protection against yttrium aluminium garnet laser-induced retinal injury via the GDNF-mediated GDNF/GFRα1/RET signalling pathway - Xi-Bin Hu; Shu-Hua Fu; Qi Luo; Jian-Zhong He; Yan-Fei Qiu; Wei Lai; Min Zhong (Journal of Biosciences, 2018)

NaF Reduces KLK4 Gene Expression by Decreasing Foxo1 in LS8 Cells - Juedan Li; Peng Wang; Jianghong Gao; Xiuzhi Fei; Yan Liu; Jianping Ruan (Biological Trace Element Research, 2018)

Complete sequence of a novel alphaendornavirus from the phytopathogenic fungus Arthrocladiella mougeotii - Xiaoqin Peng; Shexiang Gan; Xiaoting Zhang; Yingying Zhai; Lina Cai; Fei Yan; Songbai Zhang (Archives of Virology, 2018)

Onosmanones A and B, two novel quinonoid xanthenes from Onosma paniculatum - Li-Qiu Quan; Wei-Feng Dai; Fei Li; Yan-Hong Li; Xuan-Qin Chen; Rong-Tao Li; Hong-Mei Li (Natural Product Research, 2018)