Phlecarinatones H–N: Abietane-type diterpenoids from Phlegmariurus carinatus with proliferative inhibitory effect on U251 glioblastoma cells - Hua Wang; Qiang Wang; Yong-Hong Chen; Xi Chen; Dong-Kun Zheng; Zhen Xie; Du-Min Feng; Lin Liu; Jing Li; Yang Liu (Phytochemistry, 2025)

Albaillellarian (radiolaria) assemblages across the Guadalupian–Lopingian boundary (Permian) and their environmental implications - Lei Zhang; Shan Chang; Xia Wang; Marie-Béatrice Forel; Qing-Lai Feng; Wei-Hong He; Taniel Danelian; Martial Caridroit; Qian Liu; Xing-Lin Li (Palaeoworld, 2025)

Biodegradable microplastics affect tomato (Solanum lycopersicum L.) growth by interfering rhizosphere key phylotypes - Haoxin Fan; Xincheng Hong; Hehua Wang; Feng Gao; Ziqi Su; Huaiying Yao (Journal of Hazardous Materials, 2025)

Construction and application of antimicrobial ultrafiltration membranes based on electro-stimulated hollow mesoporous carbon spheres and carbon nanotubes - Ru-Yu Chang; Wen-Hao Geng; Li-Chao Jing; Jing-Yi Feng; Yue-Xin Wang; Peng-Fei Qian; Ze-Long Bao; Wenyi Wang; Di Zhang; Hong-Zhang Geng (Journal of Environmental Chemical Engineering, 2025)

The role of hydrogen in lignin pyrolysis: A density functional theory and reactive force field molecular dynamic study on a model compound - Linjia Yin; Huiyuan Wang; Tan Li; Hong Xian; Wenhao Xu; Muye Feng; Guanqun Luo; Kaige Wang (Fuel, 2025)

Geographical origins of Angelica sinensis using functional compounds and multielement with machine learning-based fusion approaches - Ping Yu; Xinwei Yan; Jiashun Hong; Daocheng Li; Feng Xiong; Ruibin Bai; Jian Yang; Lanping Guo (Food Chemistry, 2025)

A novel light-responsive sandwich-like nanocomposite film with efficient antibacterial activity for chilled beef preservation - Yirui Zhao; Hongshun Hao; Gongliang Zhang; Jingran Bi; Shuang Yan; Feng Hong; Hongman Hou (Food Bioscience, 2025)

Exploring anxiolytic peptides derived from walnut protein by an integrated approach of multivariate analysis, random forest methodology - Zishan Hong; Ying Cheng; Mingjie Zhou; Shuguang Wang; Xiaomin Li; Shiyun Feng; Guowan Su; Lin Zheng; Mouming Zhao (Food Bioscience, 2025)

Dietary pyridoxine promoted muscle protein deposition relating to PI3K/AKT/TOR pathway and the ubiquitin proteasome system in grass carp (Ctenopharyngodon idella) - Li-Fu Gong; Xiao-Qiu Zhou; Lin Feng; Pei Wu; Wei-Dan Jiang; Yao-Bin Ma; Xiao-Wan Jin; Hong-Mei Ren; Jia-Yong Tang; Fa-Li Wu; Yang Liu (Food Bioscience, 2025)

Enhance the accuracy of rice yield prediction through an advanced preprocessing architecture for time series data obtained from a UAV multispectral remote sensing platform - Xiangqian Feng; Ziqiu Li; Peixin Yang; Weiyuan Hong; Aidong Wang; Jinhua Qin; Haowen Zhang; Pavel Daryl Kem Senou; Yunbo Zhang; Danying Wang; Song Chen (European Journal of Agronomy, 2025)

S-scheme heterojunction of WO3/metal-covalent organic frameworks for artificial photosynthetic CO2 reduction - Liang Fang; Li-Wen Bai; Di Wu; Hong-Tu Che; Yanxia Jiang; Ya Wang; Hong Dong; Feng-Ming Zhang (Chemical Engineering Journal, 2025)

The structures of two polysaccharides from Fructus Corni and their protective effect on insulin resistance - Guang-Yuan Ma; Lu-Kuan Hou; Jia-Hui Guo; Jing-Chun Sun; Qiuna Nong; Yu-Fan Wang; Sheng-Wei Hu; Wen-Jing Zhao; Jin Tan; Xiao-Feng Liu; Yuan Guo; Bo-Jing Zhang; et al. (Carbohydrate Polymers, 2025)

Comparisons of pretreatment extraction methods for tree-ring radiocarbon analysis - Jingdi Qin; Zhenchuan Niu; Weijian Zhou; Yunfei Huang; Xue Feng; Dan Liang; Guowei Wang; Xuefeng Lu; Yu Huang; Hong Wang (Chemical Geology, 2025)

Peri-centrosomal localization of small interfering RNAs in C. elegans - Qile Jin; Xuezhu Feng; Minjie Hong; Ke Wang; Xiangyang Chen; Jiewei Cheng; Yan Kuang; Xiaoyue Si; Mingjing Xu; Xinya Huang; Shouhong Guang; Chengming Zhu (Science China Life Sciences, 2025)

Deletion of the Transient Receptor Potential Melastatin 2 Gene Mitigates the 6-Hydroxydopamine-Induced Parkinson’s Disease–Like Pathology - Ana Flavia F. Ferreira; Henning Ulrich; Yasuo Mori; Zhong-Ping Feng; Hong-Shuo Sun; Luiz Roberto Britto (Molecular Neurobiology, 2025)

Suitability and Bearing Behavior of PHC Pipe Piles in Underlying Mudstone - Qing-rui Feng; Hao-feng Xing; Hong-bo Chen; Hua Wei (Geotechnical and Geological Engineering, 2025)

Interdecadal variation in the relationship between ENSO and summer precipitation in the middle and lower reaches of the Yangtze River - Rong Zhi; Taichen Feng; Wenjie Dong; Yuheng Zhao; Jieli Hong (Climate Dynamics, 2025)

Late Mesozoic Wangxiang Composite Granitic Pluton, South China Block: Implications to Magma Emplacement and Evolution from Geochemical Proxies - Quan Ou; Jing-Yi Liu; Feng Zi; Bruna B. Carvalho; Xiaoping Long; Jian-Qing Lai; Kun Wang; Zi-Qi Jiang; Yi-Zhi Liu; Zheng-Lin Li; Hong-Yun Wang (Journal of Earth Science, 2025)

Oxalate-derived NiO@NiAl-layered double hydroxide core-shell material for supercapacitors - Hong-Li Yue; Hong-Yan Zeng; Wei Yan; Chao-Wei Luo; Zi-Feng Tian; Kai-Wen Xu (Applied Clay Science, 2025)

Efficient conversion and highly sensitive detection of PAEs in milk based on hydrazinolysis reaction and hydrogen bonding using SERS technique - Lili Hua; Hongmei Li; Jing-Wen Zhou; Xiao-Feng Liu; Xian-Ming Guo; Zhao-Bing Zhang; Yichuan Kou; Tang-Tang Xie; Cuihong Sheng; Lin Zhang; Sheng-Hong Liu; Fan-Li Zhang; et al. (Analytica Chimica Acta, 2025)

A feasible regulation strategy for conjugation of antibiotic resistance genes based on different bacterial quorum sensing inhibition methods - Chen-Yi Jiang; Xiao-Chi Feng; Hong-Tao Shi; Shu-Hong Gao; Wen-Qian Wang; Zi-Jie Xiao; Nan-Qi Ren (Water Research, 2025)

HDFormer: A transformer-based model for fishing vessel trajectory prediction via multi-source data fusion - Siyuan Lin; Yufei Jiang; Feng Hong; Lixiang Xu; Haiguang Huang; Bin Wang (Ocean Engineering, 2025)

A small RNA effector conserved in herbivore insects suppresses host plant defense by cross-kingdom gene silencing - Wen-Hao Han; Shun-Xia Ji; Feng-Bin Zhang; Hong-Da Song; Jun-Xia Wang; Xiao-Ping Fan; Rui Xie; Shu-Sheng Liu; Xiao-Wei Wang (Molecular Plant, 2025)

Intensification of hourly and Small watershed flooding with rising temperatures - Hong Wang; Fubao Sun; Yao Feng; Tingting Wang; Wenbin Liu (Journal of Hydrology, 2025)

Microplastics induce human kidney development retardation through ATP-mediated glucose metabolism rewiring - Bingrui Zhou; Anxiu Zhang; Yujiao Wang; Shuqi Feng; Qunhang Xue; Zhizhen Liu; Hong Zhao; Ziye Jing; Jun Xie (Journal of Hazardous Materials, 2025)

Accumulation of lipophilic and proteinophilic halogenated organic pollutants (HOPs) in the different types of feathers of laying hens - Xi Chen; Xiao-Jun Luo; Qun-Jie Feng; Yu Liu; Jun-Zhe Dai; Peng-Peng Chen; Pei-Xin Su; Qing-Rong Yang; Yan-Hong Zeng; Bi-Xian Mai (Journal of Hazardous Materials, 2025)

Microbial augmented aerobic composting for effective phthalates degradation in activated sludge - Bogui Pan; Hong Tian; Qi-Feng Liang; Hong-Jia Huang; Yi-Tong Huang; Bai-Lin Liu; Yan-Wen Li; Lei Xiang; Hai-Ming Zhao; Quan-Ying Cai; Nai-Xian Feng; Ce-Hui Mo (Journal of Environmental Management, 2025)

Heavy metals pollution and the associated ecological risks along the Luanhe River basin in North China - Dongrui Li; Bowen Zhang; Hong Li; Erwei Wu; Jiating Zhao; Qingliang Chen; Xu Bai; Yu-Feng Li; Bai Li; Gang Wu; Yuxi Gao (Journal of Environmental Management, 2025)

Innovative far-infrared radiation assisted pulsed vacuum freeze-drying of banana slices: Drying behaviors, physicochemical properties and microstructural evolution - Ming-Qiang Xu; Bu-Er Ha; Sriram K. Vidyarthi; Feng-Lun Zhang; Fan Yang; Yu-Hao Jiang; An-An Zhang; Weiqiao Lv; Hong-Wei Xiao (Innovative Food Science & Emerging Technologies, 2025)

First boron isotopes in the southern Jilin TTG series uncover a Neoarchean oceanic arc in the eastern North China Craton - Bo Liu; Jingxuan Ma; Pengfei Li; Yangbaihe Hong; Wei Feng (Gondwana Research, 2025)

Exploration of the regulatory mechanism of pulsed electric field on the aggregation behavior of soybean protein isolates - Rui Wang; Pei-Feng Guo; Jin-Peng Yang; Yan-Yan Huang; Lang-Hong Wang; Jian Li; Song-Yi Lin; Qing-Lin Sheng; Xin-An Zeng; Yong-Xin Teng (Food Hydrocolloids, 2025)

Environmentally relevant concentrations of DBDPE (decabromodiphenyl ethane) induce intestinal toxicity in silkworms (Bombyx mori L.) - Xue Luo; Rui Xing; Man Xu; Hui-Jun Jiang; Yu-Rui Wang; Ming-Yue Hu; Hao Zhang; Feng Ge; Wei Zhang; Hong-Wei Wang (Environmental Pollution, 2025)

Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China - Ming-Dao Sun; Qin Lin; Jahandar Ramezani; Jiang-Si Liu; Zheng-An Lu; Han-Qing Yang; Jiang-Hao Bai; Shi-Xi Cai; Jun-Cai Chen; Xuan-Yu Chen; Hao Cui; Guang-Chao Deng; et al. (Earth and Planetary Science Letters, 2025)

Mechanisms of manganese-modified biochar and white-rot fungi in enhancing compost humification: Boosting polyphenol pathway by lignocellulose degradation - Feng Wang; Feng Zhou; Linjie Zhang; Wenjun Liu; Yinglong Su; Yuchen Zhang; Seungkwan Hong; Min Zhan; Bing Xie; Yanbo Zhou (Chemical Engineering Journal, 2025)

A novel win–win wastewater treatment process: Recover functional element from sludge to enhances TiO2 for deep photocatalytic oxidation - Bo Sun; Yu Tian; Menglin Feng; Sihan Zhang; Hong Yang; Junmei Qin; Wenlong Bi; Xingxing Qiao; Fenwu Liu; Qingjie Hou (Chemical Engineering Journal, 2025)

Cyclodextrin-based delivery systems for chemical and genetic drugs: Current status and future - Yikun Gao; Le Sun; Chu Qiao; Yuqing Liu; Yang Wang; Rui Feng; Hong Zhang; Youxi Zhang (Carbohydrate Polymers, 2025)

An investigation into the dominant cloud microphysical processes in extreme-rain-producing storms occurred on 7 May 2017 over Southern China - Jinfang Yin; Liyan Wang; Feng Li; Haoran Li; Zhiming Zhou; Hong Wang (Atmospheric Research, 2025)

Correction to: Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent Manner - Hong Chen; Gang Yang; De-En Xu; Yu-tong Du; Chao Zhu; Hua Hu; Li Luo; Lei Feng; Wenhui Huang; Yan-Yun Sun; Quan-Hong Ma (Neuroscience Bulletin, 2025)

Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent Manner - Hong Chen; Gang Yang; De-En Xu; Yu-tong Du; Chao Zhu; Hua Hu; Li Luo; Lei Feng; Wenhui Huang; Yan-Yun Sun; Quan-Hong Ma (Neuroscience Bulletin, 2025)

Contactin -Associated protein1 Regulates Autophagy by Modulating the PI3K/AKT/mTOR Signaling Pathway and ATG4B Levels in Vitro and in Vivo - Yan Zou; Xiao Zhang; Xin-Yi Chen; Xiao-Fang Ma; Xiao-Yan Feng; Yang Sun; Tao Ma; Quan-Hong Ma; Xu-dong Zhao; De-En Xu (Molecular Neurobiology, 2025)

Comamonas squillarum sp. nov., Isolated from Intestine of Red Swamp Crayfish (Procambarus clarkii) - Shi Shi; Dao-Feng Zhang; Hong-Chuan Wang; Fu-Hui Jiang; Li-Fan Cui; Ying Huang (Current Microbiology, 2025)

Identification of stable reference genes for qPCR analysis of gene expression in Oocystis borgei under various abiotic conditions - Ning Zhang; Jiajia Ren; Ting Hong; Zhongdian Dong; Feng Li; Yulei Zhang; Xianghu Huang; Changling Li; Zhangxi Hu (Algal Research, 2025)

Research on short-impending ELF electromagnetic anomaly based on DEMETER satellite before the Wenchuan Ms8.0 earthquake - Jian-Guo Zhang; Chang-Hong Zhao; Lei Zhang; Shuang-Feng Zhang; Xuan-Ye Shen; Xiao-Dong Yang (Applied Geophysics, 2025)

Lignan and phenolic glycosides from Viburnum betulifolium fruits and their α ‑amylase and α -glucosidase inhibitory activities - Yi-Yuan Tang; Jia Chen; Hong-Juan Zhou; Wei Ji; Jian-Hua Shao; Feng-Min Zhang; Chun-Chao Zhao (Natural Product Research, 2025)

Complete genome sequence of the mango bacterial dry rot pathogen Sphingomonas carotinifaciens strain NY01 - Feng Liu; Zhongqin He; Xiaona Xie; Qiufei Ouyang; Zhengjie Zhu; Hong He (Journal of Plant Pathology, 2025)

Interaction between dietary zinc (Zn) and manganese (Mn) on growth performance, intestinal health and lipid metabolism in yellow catfish - Wu-Hong Lv; Fan Wu; Mette Sorensen; Xiao-Ying Tan; Xiao-Lei Wei; An-Gen Yu; Chong-Chao Zhong; Yu-Feng Song; Zhi Luo (Aquaculture, 2025)

Protective effects of dietary protein against nitrite stress in grass carp (Ctenopharyngodon idella): A new perspective - Hong-Ju Liu; Xiao-Qiu Zhou; Pei Wu; Wei-Dan Jiang; Yang Liu; Hong-Mei Ren; Xiao-Wan Jin; Hai-Feng Mi; Min Dong; Lu Zhang; Lin Feng (Aquaculture, 2025)

Acidosis induces autophagic cell death through ASIC1-mediated Akt/mTOR signaling in HT22 neurons - Miao Guo; Ming-Yue Qiu; Lin Zeng; Ya-Xiong Nie; Ya-Ling Tang; Yan Luo; Hong-Feng Gu (Toxicology, 2025)

Corrigendum to “Maternal Zearalenone exposure impacted ovarian follicle formation and development of suckled offspring” [Sci. Total Environ. 788 (2021) 147792] - Li Kong; Ai-Hong Zhao; Qian-Wen Wang; Yan-Qin Feng; Zi-Hui Yan; Ming-Hao Li; Fa-Li Zhang; Han Wang; Kai-Yu Shen; Ying Liu; Yu-Jiang Sun; Wei Shen; et al. (Science of The Total Environment, 2025)

Measurement of the decay Ξ 0 → Λ γ with entangled Ξ 0 Ξ ¯ 0 pairs - M. Ablikim; M.N. Achasov; P. Adlarson; O. Afedulidis; X.C. Ai; R. Aliberti; A. Amoroso; Q. An; Y. Bai; O. Bakina; I. Balossino; Y. Ban; et al. (Science Bulletin, 2025)

Mechanistic impact of Gracilaria bailinae extracts on photosynthesis and metabolism in Phaeodactylum tricornutum - Li-Gong Zou; Fu-Fang Wen; Xiao Zhang; Gang Li; Qing Wang; Hong-Ye Li; Yu-Feng Yang (Marine Environmental Research, 2025)

Moxifloxacin plus Cordyceps polysaccharide ameliorate intestinal barrier damage due to abdominal infection via anti-inflammation and immune regulation under simulated microgravity - Hong-Yun Nie; Jun Ge; Kai-Ge Liu; Yuan Yue; Hao Li; Hai-Guan Lin; Tao Zhang; Hong-Feng Yan; Bing-Xin Xu; Hong-Wei Sun; Jian-Wu Yang; Shao-Yan Si; et al. (Life Sciences in Space Research, 2025)

Associations between co-exposure to multiple heavy metals and age-related macular degeneration: A cross-sectional study - Mu-hong Wei; Ju-xiao Li; Jing Mi; Qing Wang; Feng Xu; Che Xu (Journal of Trace Elements in Medicine and Biology, 2025)

Engineering noble metal-free nickel catalysts for highly efficient liquid fuel production from waste polyolefins under mild conditions - Xinlei Han; Jiuxuan Zhang; Zhengyan Qu; Tuo Ji; Feng Zeng; Hong Jiang; Jun Huang; Zhenchen Tang; Weihong Xing; Rizhi Chen (Fuel, 2025)

Injection and storage of carbon dioxide in nitrogen-rich coal seams: Experiments and simulations - Hong Xie; Yu Liu; Yanming Zhu; Xiaozhi Zhou; Fuhua Shang; Guangjun Feng (Fuel, 2025)

Synergistic effects of ether oxygen bond/benzene ring and hydrocarbon chain structure on soot morphology and nanostructure - Wenlong Dong; Run Hong; Shunjie Feng; Bingbing Qiu; Ruiming Fang; Huaqiang Chu (Fuel, 2025)

Quantitative analysis of 4-hydroxy-2-nonenal (HNE) in fish muscle by high-performance liquid chromatography with pre-column derivatization using (2,4-dinitrophenyl)-hydrazine - Ruifang Feng; Xin Xiong; Peipei Dou; Jinlin Li; Soottawat Benjakul; Yongkang Luo; Yuqing Tan; Hui Hong (Food Chemistry, 2025)

Exploring the therapeutic potential of lupeol: A review of its mechanisms, clinical applications, and advances in bioavailability enhancement - Xia Luo; Ji Li; Zhifeng Cen; Gang Feng; Meiqi Hong; Lizhen Huang; Qinqiang Long (Food and Chemical Toxicology, 2025)

Temporal shifts in the phosphate mobilising bacterial community reveal contrasting succession patterns in response to different phosphorus sources - Zengwei Feng; Hong Gao; Ling Ding; Yongqiang Qin; Yang Zhou; Guangda Feng; Qing Yao; Honghui Zhu (Environmental Research, 2025)

Elucidating contributions of meteorology and emissions to O3 variations in coastal city of China during 2019–2022: Insights from VOCs sources - Keran Zhang; Qiaoling Chen; Youwei Hong; Xiaoting Ji; Gaojie Chen; Ziyi Lin; Feng Zhang; Yu Wu; Zhigang Yi; Fuwang Zhang; Mazhan Zhuang; Jinsheng Chen (Environmental Pollution, 2025)

Experimental study on indoor thermal and daylighting performance of different thermotropic window systems in subtropical climate - Yilin You; Xuan Yang; Xia Deng; Feng Shi; Chuyao Wang; Xiaoqiang Hong (Energy and Buildings, 2025)

Leaching kinetics combined with DFT simulation to explore the mechanism of differential phase transformation of calcium in magnesium slag induced by HCl and the preparation of calcium carbonate by electrolytic carbonization - Ren-yun Zhang; Yan Liu; Zhi-yu Fan; Ji-dong Li; Yi-yong Wang; Ting-an Zhang; Hong-xuan Xing; Yi-feng Liu; Xue-qiang Gong (Chemical Engineering Journal, 2025)

Hyaluronic acid-functionalized ruthenium photothermal nanoenzyme for enhancing osteosarcoma chemotherapy: Cascade targeting and bidirectional modulation of drug resistance - Weifeng Chen; Hao Feng; Yinyin Mo; Zhihui Pan; Shichen Ji; Hong Liang; Xing-Can Shen; Bang-Ping Jiang (Carbohydrate Polymers, 2025)

Electrostatic repellent dispersion method for green and cost-effective aqueous radiative cooling paint - Jipeng Fei; Di Han; Kai Zhou; See Wee Koh; Junyu Ge; Jun Yan Tan; Bing Feng Ng; Zhong Chen; Lili Cai; Hong Li (Building and Environment, 2025)

Areal Health Risk Assessment Using Soil Bioaccessible Heavy Metal(loid)s Around Industrial Area in Nanjing, Southeast China - Yangxiaoxiao Shi; Yadan Wang; Xueqing Zhang; Feng Zhang; Jiaqi Cui; Zhineng Hong; Jun Jiang; Renkou Xu (Exposure and Health, 2025)

Shear strain prediction of reservoir landslide based on FBG monitoring and bagging-MLP algorithm - Jia Wang; Hong–hu Zhu; Xiao Ye; Feng Tian; Wei Zhang; Hou–zhi Li; Hua–fu Pei (Bulletin of Engineering Geology and the Environment, 2025)

Geographical and environmental drivers of ureolytic microbial communities and their roles in nitrogen cycling under fertilization - Haoxin Fan; Ziqi Su; Xincheng Hong; Feng Gao; Huaiying Yao (Applied Soil Ecology, 2025)

Field study on the dynamic characteristics of sewage collection in a circular aquaculture tank - Yanfei Wu; Fukun Gui; Jianxin Yang; Hongfang Qi; Hong Zhang; Yang Wang; Dejun Feng; Qingjing Zhang (Aquaculture International, 2025)

Spatial-Temporal Evolution of Maritime Accident Hot Spots in the East China Sea: A Space-Time Cube Representation - Yiyang Feng; Daozheng Huang; Xijie Hong; Huanxin Wang; Sean Loughney; Jin Wang (Journal of Marine Science and Engineering, 2025)
As public concern for maritime safety grows, there is a pressing need to delve deeper into the root causes of maritime accidents and develop effective preventive strategies. Spatial-temporal analysis stands out as a powerful approach to pinpointing accident hot spots. While previous research has shed light on the spatial aspects of these incidents, a comprehensive understanding of their temporal dimensions remains elusive. This paper bridges this gap by leveraging the Space-Time Cube tool in conjunction with traditional Kernel Density analysis to chart the spatial-temporal dynamics of maritime accident hot spots. Focusing on the East China Sea, a region notorious for its high incidence of maritime accidents and home to numerous world-class ports, we present a case study that offers fresh insights. Data spanning from 1994 to 2020, sourced from the Lloyd’s List Intelligence (LLI) database, reveal the evolving landscape of maritime accidents in the area. Notably, since 2005, the Yangtze River Delta Region in China has emerged as a persistent hot spot for accidents, underscoring its significance in maritime safety discourse. Furthermore, our analysis from the 2010s detects a new hot spot expanding towards the southwest of Kaohsiung Port, China, signaling a burgeoning area of concern for maritime safety. While the Fujian coast of China has seen its share of accidents, it is not qualified as a hot spot zone. The Space-Time Cube proves to be an indispensable tool in unraveling the progression of maritime accidents, and our findings indicate that maritime accidents in certain areas may not be merely random occurrences but exhibit intricate patterns.

The research of nicotinamide and β-arbutin on reducing melanin content in the skin of leopard coral grouper (Plectropomus leopardus) - Zhi Bin Sun; Shi Ying Liu; Xin An Wang; Ai Jun Ma; Zhi Hui Huang; Zhi Feng Liu; Wei Heng Sun; Peng Fei Yan; Dong Hui Gou; Hui Yu Xiao; Hao Zhe Li; Vorathep Muthuwan; et al. (Aquaculture, 2025)

New insights of 4-Methylesculetin in alleviating the effect of aflatoxin B1 on flesh quality of grass carp (Ctenopharyngodon idella) - Xiang-Ning He; Jia-Jia Zhang; Wei-Dan Jiang; Pei Wu; Yang Liu; Hong-Mei Ren; Xiao-Wan Jin; He-Qun Shi; Xiao-Qiu Zhou; Lin Feng (Aquaculture, 2025)

Impact of attitude, behaviour and opinion of e-scooter and e-bike riders on collision risk in Singapore - Raunaq Nayar; Milan Paudel; Fook Fah Yap; Hong Xu; Yiik Diew Wong; Feng Zhu (Travel Behaviour and Society, 2025)

Description of Albidovulum litorale sp. nov., Albidovulum marisflavi sp. nov., Albidovulum salinarum sp. nov., and Albidovulum sediminicola sp. nov., and proposal for reclassification of the genus Defluviimonas as a later heterotypic synonym of Albidovulum - Wei He; Dao-Feng Zhang; Xing-Jie Li; Hong-Chuan Wang; Lin-Qiong Wang; Yang Yuan (Systematic and Applied Microbiology, 2025)

Consuming probiotics protects against cadmium exposure from rice consumption while promotes gut health: An assessment based on a mouse model - Jin-Feng Xi; Lei Zhou; Yao-Sheng Zhang; Xin-Ying Lin; Shan Chen; Rong-Yue Xue; Dongmei Zhou; Hong-Bo Li (Science of The Total Environment, 2025)

Strategies for crop straw management in China's major grain regions: Yield-driven conditions and factors influencing the effectiveness of straw return - Jia Cheng; Bai-Jian Lin; Jin-Sai Chen; Hong-Xuan Duan; Yuan-Feng Sun; Xin Zhao; Yash Pal Dang; Zhi-Yu Xu; Hai-Lin Zhang (Resources, Conservation and Recycling, 2025)

Functional characterization of chlorophyll b reductase NON-YELLOW COLORING 1 in Medicago truncatula - Min Wang; Limei Hong; Weizhen Zhang; Yiteng Xu; Feng Yuan; Chuanen Zhou; Chunyan Hou; Lu Han (Plant Science, 2025)

ent-Abietane-type lactones with anti-inflammatory activity from Euphorbia helioscopia - Hong-Ying Yang; Pei-Zhi Huang; Wei-Jiao Feng; Pei-Wei Si; Kun Gao; Jian-Jun Chen (Phytochemistry, 2025)

Z/E configuration controlled by a Taxus sesquiterpene synthase facilitating the biosynthesis of (3Z,6E)-α-farnesene - Xue Tang; Xian-Jing Zhang; Jing-Feng Pan; Kai Guo; Chun-Lin Tan; Qiao-Zhuo Zhang; Li-Ping Long; Rui-Feng Ding; Xue-Mei Niu; Yan Liu; Sheng-Hong Li (Phytochemistry, 2025)

Recent progress on triterpenoid derivatives and their anticancer potential - Zi-Xuan Zhao; Qiong-Yu Zou; Ying-Hong Ma; Susan L. Morris‐Natschke; Xiang-Yuan Li; Lin-Chun Shi; Guo-Xu Ma; Xu‐Dong Xu; Mei‐Hua Yang; Zi-Jian Zhao; Yuan-Xiang Li; Jing Xue; et al. (Phytochemistry, 2025)

Construction of S-scheme BiOCl/Bi24O31Cl10 heterojunction by thermally induced in-situ phase transition strategy for photocatalytic degradation of ciprofloxacin - Yuan Wei; Chao Liu; Xin Li; Hong-Yu Wang; Yu-Miao Yang; Gao-Feng Shi; Guo-Ying Wang (Journal of Water Process Engineering, 2025)

Analytical model for reactive contaminant back-diffusion from low-permeability aquitards with internal source zones - Xiang-Hong Ding; Shi-Jin Feng; Zhang-Wen Zhu (Journal of Hydrology, 2025)

Highly selective capture of Ni2+ from complex environments by a sandwich-like layered metal sulfide ion exchanger - Mingdong Zhang; Qisheng Hong; Yuan Aocheng; Yan Zhang; Xiaoying Huang; Meiling Feng; Jingli Mu (Journal of Hazardous Materials, 2025)

Development of a coupled model to simulate and assess arsenic contamination and impact factors in the Jinsha River Basin, China - Yidian Sun; Xu Zhang; Hong Peng; Wenting Zhou; Anna Jiang; Feng Zhou; Hao Wang; Wanshun Zhang (Journal of Environmental Sciences, 2025)

Iron isotopes of Chang'e-5 soil and mineral components: Implications for post-eruption processes on lunar surface - Yiheng Li; Zaicong Wang; Yuqi Qian; Wen Zhang; Yantong Feng; Hong Liu; Keqing Zong; Qi He; Zhenbing She; Xiang Wu; Ming Li; Zhaochu Hu; et al. (Icarus, 2025)

3D hot spot construction on the hydrophobic interface with SERS tags for quantitative detection of pesticide residues on food surface - Yan-Hui Wang; Chen Huang; Xiao Wu; Xiao-Feng Liu; En-Ming You; Sheng-Hong Liu; An Wang; Shangzhong Jin; Fan-Li Zhang (Food Chemistry, 2025)

Bioconversion of agriculture by-products with functionally enhanced Streptomyces sp. SCUT-3: Fish skin as a model - Jing-Tao Ni; Ming-Shu Zhang; De-lin Lu; Wen-jun Lu; Lei Wu; Zhen-dong Yang; Can Qin; Zhen-jie Dai; Zhi-wei Li; Wen-jing Feng; Hua-hong Cai; Jia-rui Zhang; et al. (Food Chemistry, 2025)

Ampelopsis grossedentata tea polysaccharide alleviates D-galactose-induced aging in mice and regulates gut microbiota - Jiani Pan; Feng Chen; Leilei Yu; Kan Hong; Zi Ye; Qingsong Zhang; Chengcheng Zhang; Jianxin Zhao; Qixiao Zhai; Fengwei Tian (Food Bioscience, 2025)

Metal/organic interface carrier quenching suppression for stable and efficient near-infrared quantum dot light-emitting diodes - Wan-Shan Shen; Yang Liu; Xingtong Chen; Hong-Wei Duan; Jia-Lin Pan; Zhong-Da Zhang; Feng Zhao; Zeke Liu; Sui-Dong Wang; Wanli Ma; Song Chen; Ya-Kun Wang; et al. (Chemical Engineering Journal, 2025)

Phase transfer and photodegradation of DBP in water–sediment systems explored by compound-specific isotope analysis - Jin-Ru Feng; Hong-Gang Ni (Chemical Engineering Journal, 2025)

Engineered dispersed-structural fluorescent nanoprobes enable fast and long-lasting tracking of Nitric oxide in vivo - Yue Wu; Zhiyuan Zheng; Feng Ni; Ayse Basak Kayitmazer; Ayyaz Ahmad; Naveed Ramzan; Wei-Hong Zhu; Tao Xie; Zhiqian Guo; Yisheng Xu (Chemical Engineering Journal, 2025)

Dietary Iron Overload Triggers Hepatic Metabolic Disorders and Inflammation in Laying Hen - Yue Li; Lan-Xin Li; Han Cui; Wan-Xue Xu; Hong-Yu Fu; Jiu-Zhi Li; Rui-Feng Fan (Biological Trace Element Research, 2025)

Cross-sectional and Longitudinal Associations Between Metal Mixtures and Serum C3, C4: Result from the Manganese‑exposed Workers Healthy Cohort - Sencai Lin; Junxiu He; Yinghua Zhou; Yu Bao; Xiuming Feng; Hong Cheng; Haiqing Cai; Sihan Hu; Lin Wang; Yuan Zheng; Mengdi Zhang; Qinghua Fan; et al. (Biological Trace Element Research, 2025)

Transcriptome analysis of tilapia streptococcus agalactiae in response to baicalin - Qing-Qin Huang; Shao-Long Liu; Ji-Hui Huang; Fei Wang; Zi-Chen Zhao; Heng-Wei Deng; Chuan Lin; Wei-Liang Guo; Zhi-Hong Zhong; Jian-Long Li; Dong-Dong Zhang; Shi-Feng Wang; et al. (Genes & Genomics, 2025)

Insight into the anti-inflammatory sulfated polysaccharides from Sargassum carpophyllum and structure-function relationships - Zihao Li; Ziye Zhang; Yaqi Feng; Yatao Guo; Zhenxing Li; Hong Lin (Algal Research, 2025)

Roseobacter sinensis sp. nov., a marine bacterium capable to synthesize arachidonic acid - Hong-Chuan Wang; Meng-Han Huang; Dan-Yuan Guo; Wen-Li Liu; Zi-Wen Yang; Dao-Feng Zhang; Wen-Jun Li (Antonie van Leeuwenhoek, 2025)

Interventions of river connectivity and land use on indices of biotic integrity (IBIs) in plain river networks - Yufan Lu; Yaoyi Liu; Hong Qin; Shasha Ma; Xuebing Bai; Feng Xu; Cui Wang; Lei Shi; Yue Che (Environmental Monitoring and Assessment, 2024)

Evaluating the impact of dermal absorption on internal doses of dechlorane plus in Chinese e-waste recycling employees - Yao-Yuan Wan; Xiao-meng Cheng; Xing-Hong Li; Feng-Shuang Wang; Yuan-Yuan Li; Jing Li; Zhan-Fen Qin (Chemosphere, 2024)

Enrichment and characterization of thermophilic anaerobic ammonium oxidizing bacteria from hot spring - Xiao-Wei Wang; Xin Tan; Cheng-Cheng Dang; Lu-Yao Liu; Xuan Wang; Zhi-Cheng Zhao; Hong-Yu Ren; Bing-Feng Liu; Guo-Jun Xie (Water Research, 2024)

Rapid cycling and emission of volatile sulfur compounds in the eastern Indian Ocean: Impact of runoff inputs and implications for balancing atmospheric carbonyl sulfide budget - Feng Xu; Hong-Hai Zhang; Xiao-Song Zhong; Gao-Bin Xu; Shi-Bo Yan; Jin-Wei Wu; Jian Wang; Xuan Ji; Gui-Peng Yang; Zhao-Hui Chen (Water Research, 2024)

Experimental study of methane oxidation efficiency in three configurations of earthen landfill cover through soil column test - H.W. Liu; Y. Huang; S. Feng; S.Q. You; Y. Hong; L.D. Shen (Waste Management, 2024)

Study on the effect of conditioner on NO precursor control behavior from sewage sludge pyrolysis: Focusing on conditioner assessments and in-situ fixation mechanism - Shan Cheng; Ting Yang; Jingchun Huang; Hong Tian; Wei Zhang; Feng Xin; Yu Qiao (Waste Management, 2024)

Heavy metals in sediments of the river-lake system in the Dianchi basin, China: Their pollution, sources, and risks - Hong-Yi Liang; Ya-Hui Zhang; Shi-Lin Du; Jia-Le Cao; Ya-Feng Liu; Hao Zhao; Ting-Ting Ding (Science of The Total Environment, 2024)

Investigating the environmental dynamics of emerging pollutants in response to global climate change: Insights from bibliometrics-based visualization analysis - Bogui Pan; Hong Tian; Boyou Pan; Ting Zhong; Miao Xin; Jinhua Ding; Junyu Wei; Hong-Jia Huang; Jing-Qian Tang; Fengtao Zhang; Nai-Xian Feng; Ce-Hui Mo (Science of The Total Environment, 2024)

Prevalence, transmission and genomic epidemiology of mcr-1-positive colistin-resistant Escherichia coli strains isolated from international airplane waste, local resident fecal and wastewater treatment plants - Jun Feng; Min Jia; Yuan Zhuang; Zhen Xu; Yong Chen; Jiayi Fei; Jiahui Xia; Liang Hong; Jing Zhang; Huanyu Wu; Xin Chen; Min Chen (Science of The Total Environment, 2024)

Corrigendum to “Comparative efficiency of the SWAT model and a deep learning model in estimating nitrate loads at the Tuckahoe creek watershed, Maryland” [Sci. Total Environ. 954 (2024) 176256] - Jiye Lee; Dongho Kim; Seokmin Hong; Daeun Yun; Dohyuk Kwon; Robert L. Hill; Feng Gao; Xuesong Zhang; Kyung Hwa Cho; Sangchul Lee; Yakov Pachepsky (Science of The Total Environment, 2024)

Carbonate precipitation-derived CO2 outgassing offsets the mineral weathering sink in the orogenic regime of southwestern Taiwan: Insights from triple Sr isotopes - Hou-Chun Liu; Yun-Cian Lin; Yan-Hong Chen; Meng-Xuan Li; Chen-Feng You; Kuo-Fang Huang; Wei-Jen Huang; Hung-Chun Chao (Science of The Total Environment, 2024)

Environmental contamination and risks of organic UV filters: Source, discharge, analytical methods and implications for ecological and human health - Yue-hong Sun; Heng-Yu Wu; Feng-Qi Xie; Jia-Ru Ma; Qin-Lin Tang; Yan-Fen Chen; Hao Li; You-Sheng Liu; Guang-Guo Ying (Science of The Total Environment, 2024)

A mixed layer height parameterization in a 3-D chemical transport model: Implications for gas and aerosol simulations - Hyeonmin Kim; Rokjin J. Park; Song-you Hong; Do-Hyeon Park; Sang-Woo Kim; Yujin J. Oak; Xu Feng; Haipeng Lin; Tzung-May Fu (Science of The Total Environment, 2024)

Comparative efficiency of the SWAT model and a deep learning model in estimating nitrate loads at the Tuckahoe creek watershed, Maryland - Jiye Lee; Dongho Kim; Seokmin Hong; Daeun Yun; Dohyuck Kwon; Robert L. Hill; Feng Gao; Xuesong Zhang; Kyung Hwa Cho; Sangchul Lee; Yakov Pachepsky (Science of The Total Environment, 2024)

Numerical simulation and analysis of UUV docking with a Seabed Moored Floating Dock - Jingqian Guo; Hua Tan; Jun Liu; Wei Feng; Zheng Peng; Yusha Liu; Jun-Hong Cui (Ocean Engineering, 2024)

Role of molybdenum in ameliorating busulfan-induced infertility in female mice - Feng-jun Liu; Yu-ling Zhang; Xiao-shan Wang; Ya-qin Zhao; Hong-wei Wang (Journal of Trace Elements in Medicine and Biology, 2024)

A mycoheterotrophic orchid uses very limited soil inorganic nitrogen in its natural habitat - Wei Zhang; Jiao Qin; Jing-Qiu Feng; Xiu-Mei Dong; Hong Hu; Shi-Bao Zhang (Journal of Plant Physiology, 2024)

Antibiotic resistance at environmental multi-media interfaces through integrated genotype and phenotype analysis - Chen-Xi Fu; Chen Chen; Qian Xiang; Yi-Fei Wang; Lu Wang; Feng-Yuan Qi; Dong Zhu; Hong-Zhe Li; Li Cui; Wei-Li Hong; Matthias C. Rillig; Yong-Guan Zhu; et al. (Journal of Hazardous Materials, 2024)

Removal of 48 per- and polyfluoroalkyl substances (PFAS) throughout processes in domestic and general industrial wastewater treatment plants: Implications for emerging alternatives risk control - Yueqing Zhang; Ruochen Dong; Feng Ge; Minghui Hong; Zhanghao Chen; Yunqiao Zhou; Jing Wei; Cheng Gu; Deyang Kong (Journal of Hazardous Materials, 2024)

Lipidomics analysis of microalgal lipid production and heavy metal adsorption under glycine betaine-mediated alleviation of low-temperature stress - Xueting Song; Fanying Kong; Bing-Feng Liu; Qingqing Song; Nan-Qi Ren; Hong-Yu Ren (Journal of Hazardous Materials, 2024)

Performance and mechanism of the biochar-supported Ni0/Co0/MnO composite catalyst for peroxymonosulfate activation to degrade iopamidol - Meijuan Gao; Hong Wei; Qian Cai; Ruijie Teng; Junqi Song; Feng Pan; Huaien Li (Journal of Environmental Chemical Engineering, 2024)

Study on the degradation performance of coking wastewater using an in-situ enhanced Fe2+/Fe3+ cycle dual-cathode Electro-Fenton system - Chengwang Zhao; Yufang Ran; Yao Gong; Chen Hong; Yi Xing; Yunxiao Sun; Hao Wang; Wei Ling; Yijie Wang; Weibo Feng; Jiachen Hou; Xinlin Zhai; et al. (Journal of Environmental Chemical Engineering, 2024)

Mechanism of membrane fouling mitigation by microalgae biofilm formation for low C/N mariculture wastewater treatment: EPS characteristics, composition and interfacial interaction energy - Yanbo Liu; Jing Zhu; Weirun Li; Binghan Xie; Guoyu Zhang; Yi Ding; Feng Liu; Haili Tan; Yuhong Jia; Hong You; Zhipeng Li (Journal of Environmental Chemical Engineering, 2024)

Revealing the synergistic antibacterial mechanisms of resveratrol (RES) and pulsed electric field (PEF) against Acetobacter sp - Debao Niu; Xiaoqin Feng; Ailin Zhang; Kai Li; Lang-Hong Wang; Xin-An Zeng; Shuangfei Wang (Food Research International, 2024)

Constructing in-situ and real-time monitoring methods during soy sauce production by miniature fiber NIR spectrometers - Zhankai Zhang; Yanhua Ding; Feng Hu; Zhan Liu; Xiaodong Lin; Jiangyan Fu; Qingyu Zhang; Zhi-hong Zhang; Haile Ma; Xianli Gao (Food Chemistry, 2024)

Structural properties and antioxidant capacity of different aminated starch-phenolic acid conjugates - Feng-Kun An; Meng-Yun Li; Hai-Lu Luo; Xing-Long Liu; Zhen Fu; Min-Hong Ren (Food Chemistry, 2024)

Immunoprotective effect of recombinant Lactobacillus plantarum expressing largemouth bass virus MCP on largemouth bass - Yong-Lei Yang; Rong-Rong Zhang; Jing-Yi Pang; Jun-Hong Xing; Tian-Kui Guo; Chun-Wei Shi; Gui-Lian Yang; Hai-Bin Huang; Yan-Long Jiang; Jian-Zhong Wang; Xin Cao; Nan Wang; et al. (Fish & Shellfish Immunology, 2024)

A proposed biomarker for human citric acid ester (CAE) exposure, and the potential disturbance on human lipid metabolism - Yayun Zhang; Qianyu Chen; Dan Weng; Hong Sun; Feng Zhu; Fei Shen; Yonglin Zhou; Guanyong Su (Environmental Research, 2024)

Spatiotemporal variations of PM2.5 organic molecular markers in five central cities of the Yangtze River Delta, East China in autumn and winter: Implications for regional and local sources of organic aerosols - Wei Feng; Guihong Dong; Wanqing Qi; Yizhen Wang; Xiangyu Zhang; Ke Li; Hong Liao; Yuhang Wang; Zhijuan Shao; Mingjie Xie (Environmental Pollution, 2024)

Exceptional heatwaves and mortality in Europe: Greater impacts since the coronavirus disease 2019 outbreak - Zhiwei Li; Yinguang Fan; Zhiwei Xu; Hung Chak Ho; Shilu Tong; Cunrui Huang; Zhongliang Bai; Yiming Gai; Wenjun Cheng; Jihong Hu; Yufan Feng; Hao Zheng; et al. (Environmental Pollution, 2024)

Role of physical and chemical nonequilibriums in ISCO remediation of contaminated soils - Shi-Jin Feng; Hao-Yue Wang; Wen-Tao Wang; He Chen; Hong-Xin Chen (Computers and Geotechnics, 2024)

Advancements in research on the carbon dots nanomaterials in immune modulate and immunotherapy - He Feng; Yangjian Hong; Qinglin Li; Songnan Qu (Chemical Engineering Journal, 2024)

In-situ immobilization of Fe PBA in the zeolite structure for efficient degradation of benzalkonium chloride: Towards compressed reaction site loss and promoted PMS utilization - Qing Zhong; Ting Zhang; Zhi Huang; Longhui Su; Yuwei Xue; Ran Gao; Han Feng; Junming Hong (Chemical Engineering Journal, 2024)

A zircon petrochronologic perspective on raising the central Tibetan crust - Shu-Hui Ren; Yun-Chuan Zeng; Roberto Weinberg; Ji-Feng Xu; Jian-Lin Chen; Bao-Di Wang; Feng Huang; Xi-Jun Liu; Hong-Xia Yu; Ming-Jian Li (Chemical Geology, 2024)

Antioxidants alleviated low-temperature stress in microalgae by modulating reactive oxygen species to improve lipid production and antioxidant defense - Xueting Song; Fanying Kong; Bing-Feng Liu; Qingqing Song; Nan-Qi Ren; Hong-Yu Ren (Bioresource Technology, 2024)

Comparative analysis of hydrogel-based thermotropic glazing and fixed horizontal overhangs in building performance - Xiaoqiang Hong; Xuan Yang; Yilin You; Feng Shi; Fan Yang; Chuanrong Cui; Yingming Gong; Dewei Qian (Building and Environment, 2024)

Cohort Profile: TRacing Etiology of Non-communicable Diseases (TREND): Rationale, Progress and Perspective - Hui-Ying Ren; Ying Lv; Bei-Ning Ma; Chang Gao; Hong-Mei Yuan; Hai-Hong Meng; Zheng-Qian Cao; Ya-Ting Chen; Yan-Xi Zhang; Yu-Ting Zhang; Wei Liu; Yu-Ping Fan; et al. (Phenomics, 2024)
The TRacing Etiology of Non-communicable Diseases (TREND) cohort is a prospective longitudinal cohort and biobank that is mainly based in Ma’anshan, Anhui Province, China. The primary aim of the study is to decipher comprehensive molecular characterization and deep phenotyping for a broad spectrum of chronic non-communicable diseases (NCDs), which focuses on providing mechanistic insights with diagnostic, prognostic and therapeutic implications. The recruitment was initiated in 2023 and is expected to complete in 2025 with 20,000 participants originated from urban and rural area. In the first phase, 3360 participants were recruited. Follow-up visits are scheduled annually and intervally for a total of 30 years. The cohort includes individuals aged over 18 years. Two participants with first-degree linkage were recruited from a household. The age distribution of recruited participants was stratified into four categories: 18–45, 45–55, 55–65, and ≥65 years, aligning with the population proportions of Ma’anshan. Meanwhile, the gender distribution was controlled by pairing men and women from the same household. Data collected at baseline includes socio-economic information, medical history, lifestyle and nutritional habits, anthropometrics, blood oxygen, electrocardiogram (ECG), heart sound, as well as blood, urine and feces tests results. Molecular profiling includes genome, proteome, metabolome, microbiome and extracellular vesicles -omics. Blood, urine and fecal samples are collected and stored at −80 °C in a storage facility for future research.

A rare KMT2A::CBL transcript in an acute monoblastic leukemia patient with an unfavorable outcome - Jinglei Yu; Fengmei Song; Mingming Zhang; Pingnan Xiao; Jingjing Feng; Ruimin Hong; Yongxian Hu; He Huang; Guoqing Wei (Molecular Biology Reports, 2024)
Background Lysine [K] methyltransferase 2A ( KMT2A , previously known as MLL ) gene rearrangements are common in acute leukemias of various lineages and are associated with features such as chemotherapy resistance and rapid relapse. KMT2A::CBL is a rare fusion of unknown pathogenesis generated by a unique interstitial deletion of chromosome 11 that has been reported across a wide age range in both acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) patients. The leukemogenic effect of the KMT2A::CBL rearrangement and its association with clinical prognosis have not been well clarified. Methods and results We report the case of a 64-year-old female who was diagnosed with acute monoblastic leukemia (M5a) and who acquired the rare KMT2A::CBL fusion. The patient received multiple cycles of therapy but did not achieve remission and eventually succumbed to severe infection and disease progression. Additionally, we characterized the predicted KMT2A-CBL protein structure in this case to reveal the underlying leukemogenic mechanisms and summarized reported cases of hematological malignancies with KMT2A::CBL fusion to investigate the correlation of gene rearrangements with clinical outcomes. Conclusions This report provides novel insights into the leukemogenic potential of the KMT2A::CBL rearrangement and the correlation between gene rearrangements and clinical outcomes.

CDKN2A promoter methylation enhances self-renewal of glioblastoma stem cells and confers resistance to carmustine - Jing Wang; Yan-feng Xi; Qi Zhao; Jiang-hong Guo; Zhen Zhang; Mao-bai Zhang; Jiang Chang; Yue-qin Wu; Wen Su (Molecular Biology Reports, 2024)
Background Glioblastoma, a highly aggressive form of brain cancer, poses significant challenges due to its resistance to therapy and high recurrence rates. This study aimed to investigate the expression and functional implications of CDKN2A, a key tumor suppressor gene, in glioblastoma cells, building upon the existing background of knowledge in this field. Method Quantitative reverse transcription PCR (qRT-PCR) analysis was performed to evaluate CDKN2A expression in U87 glioblastoma cells compared to normal human astrocytes (NHA). CDKN2A expression levels were manipulated using small interfering RNA (siRNA) and CDKN2A overexpression vector. Cell viability assays and carmustine sensitivity tests were conducted to assess the impact of CDKN2A modulation on glioblastoma cell viability and drug response. Sphere formation assays and western blot analysis were performed to investigate the role of CDKN2A in glioblastoma stem cell (GSC) self-renewal and pluripotency marker expression. Additionally, methylation-specific PCR (MSP) assays and demethylation treatment were employed to elucidate the mechanism of CDKN2A downregulation in U87 cells. Result CDKN2A expression was significantly reduced in glioblastoma cells compared to NHA. CDKN2A overexpression resulted in decreased cell viability and enhanced sensitivity to carmustine treatment. CDKN2A inhibition promoted self-renewal capacity and increased pluripotency marker expression in U87 cells. CDKN2A upregulation led to elevated protein levels of p16INK4a, p14ARF, P53, and P21, which are involved in cell cycle regulation. CDKN2A downregulation in U87 cells was associated with high promoter methylation, which was reversed by treatment with a demethylating agent. Conclusion Our findings demonstrate that CDKN2A downregulation in glioblastoma cells is associated with decreased cell viability, enhanced drug resistance, increased self-renewal capacity, and altered expression of pluripotency markers. The observed CDKN2A expression changes are mediated by promoter methylation. These results highlight the potential role of CDKN2A as a therapeutic target and prognostic marker in glioblastoma.

Genome-Wide Characterization of ABC Transporter Genes and Expression Profiles in Red Macroalga Pyropia yezoensis Expose to Low-Temperature - Lin Tian; Lan Wu; Xue-Feng Zhong; Li-Hong Ma; Guo-Ying Du (Marine Biotechnology, 2024)

MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase–anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte - Li-Hua Fan; Shu-Tao Qi; Zhen-Bo Wang; Ying-Chun Ouyang; Wen-Long Lei; Yue Wang; Ang Li; Feng Wang; Jian Li; Li Li; Yuan-Yuan Li; Yi Hou; et al. (Histochemistry and Cell Biology, 2024)

Influence of Selenium Supplementation on Mercury Levels in hair of Metropolitan Residents in China: Spatial Distribution, Impact Factors, and Antagonism - Geting Wang; Qianqian Hong; Jian Mei; Jinyi Chen; Wansheng Wu; Feng Han; Jingchen Xing; Shijian Yang (Exposure and Health, 2024)

Classification method of infrasound events based on the MVIDA algorithm and MS-SE-ResNet - Xiao-Feng Tan; Xi-Hai Li; Chao Niu; Xiao-Niu Zeng; Hong-Ru Li; Tian-You Liu (Applied Geophysics, 2024)

Well Logging Stratigraphic Correlation Algorithm Based on Semantic Segmentation - Cai-zhi Wang; Xing-yun Wei; Hai-xia Pan; Lin-feng Han; Hao Wang; Hong-qiang Wang; Han Zhao (Applied Geophysics, 2024)

Thalassospira aquimaris sp. nov. and Winogradskyella marincola sp. nov. two marine bacteria isolated from an agar-degrading co-culture - Zi-Yue Fu; Dao-Feng Zhang; Meng-Han Huang; Hong-Chuan Wang; Xiao-Ye Chen; Yu-Fang Yao; Yang Yuan; Wen-Jun Li (Antonie van Leeuwenhoek, 2024)

Description of Nesterenkonia aerolata sp. nov., an actinobacterium isolated from air of manufacturing shop in a pharmaceutical factory - Ming-Hui Song; Wen-Long Ma; Ning Zhang; Wei He; Hong-Chuan Wang; Shuang Wang; Yi-Ling Fan; Dao-Feng Zhang (Antonie van Leeuwenhoek, 2024)

Bisabolane-type sesquiterpenoids and bacillibactin from the marine-derived fungus Aspergillus sydowii SCSIO 41041 and their enzyme inhibiting activity - Ying-Ying Song; Qing-Xia Liu; Xiao-Yan Pang; Zhi-Yun Chen; Hong-Hui Huang; Jun-Feng Wang; Yong-Hong Liu (Natural Product Research, 2024)

The different impacts of functional network centrality and connectivity on the complexity of brain signals in healthy control and first-episode drug-naïve patients with major depressive disorder - Shanling Ji; Wei An; Jing Zhang; Cong Zhou; Chao-Gan Yan; Xiao Chen; Li-Ping Cao; Wei Chen; Yu-Qi Cheng; Yi-Ru Fang; Qi-Yong Gong; Wen-Bin Guo; et al. (Brain Imaging and Behavior, 2024)

Detection of color phenotype in strawberry germplasm resources based on field robot and semantic segmentation - Ningyuan Yang; Zhenyu Huang; Yong He; Wenfei Xiao; Hong Yu; Lihua Qian; Yixin Xu; Yimin Tao; Ping Lyu; Xiaohan Lyu; Xuping Feng (Computers and Electronics in Agriculture, 2024)

Bee venom prompts the inhibition of gefitinib on proliferation, migration, and invasion of non-small cell lung cancer cells via EGFR-mediated autophagy - Shihui Xie; Shuo Han; Jietao Gong; Zhiyuan Feng; Yang Sun; Hong Yao; Peiying Shi (Toxicon, 2024)

Alendronate sodium induces G1 phase arrest and apoptosis in human umbilical vein endothelial cells by inhibiting ROS-mediated ERK1/2 signaling - Yi Feng; Shao-Qin Tu; Yu-Luan Hou; Yi-Ting Shao; Lin Chen; Zhi-Hui Mai; Yu-Xuan Wang; Jia-Ming Wei; Sai Zhang; Hong Ai; Zheng Chen (Toxicology, 2024)

Short-term sedimentary evidence for increasing diatoms in Arctic fjords in a warming world - Fu-Tao Fang; Zhuo-Yi Zhu; Fred Wenger; Jian-Zhong Ge; Jin-Zhou Du; Bing Deng; Hong-Mei Ma; Rui-Feng Zhang; Yu Zhang (Science of The Total Environment, 2024)

Hydrology controls sulfuric acid-mediated weathering in an orogenic regime of southwestern Taiwan - Hou-Chun Liu; Meng-Xuan Li; Chen-Feng You; Yan-Hong Chen; Kuo-Fang Huang; Chuan-Hsiung Chung; Guan-Wei Lin (Science of The Total Environment, 2024)

Microbial communities and functions are structured by vertical geochemical zones in a northern peatland - Hong-Yan Wang; Zhi-Guo Yu; Feng-Wu Zhou; Julio-Castillo Hernandez; Annkathrin Grandjean; Harald Biester; Ke-Qing Xiao; Klaus-Holger Knorr (Science of The Total Environment, 2024)

The influence of mudstone lithofacies sedimentation on the development of shale oil “sweet-spot intervals” within large down-warped lacustrine basins in China - Youliang Feng; Zhi Yang; Wenqi Jiang; Hong Zhang; Tianshu Zhang; Chang Liu; Pan Li; Jichang Zhu; Xiaoni Wang (Marine and Petroleum Geology, 2024)

Process exploration of domestication, start-up and rapid recovery strategies for anaerobic digestion of sole corn stover: Methane production efficiency and dominant microbial responses - Haipeng Wang; Hao Sun; Hong-Yu Ren; Guangli Cao; Guo-Jun Xie; Defeng Xing; Nan-Qi Ren; Bing-Feng Liu (Journal of Cleaner Production, 2024)

Understanding the fouling characteristics in ultrafiltration membrane for marine algae-laden seawater pretreatment: Focus on the role of algal extracellular organic matter - Weilong Yang; Feng Zhou; Jaewon Lee; Junghyun Kim; Da Yun Kwon; Youngjin Kim; Hongqiang Ren; Seungkwan Hong; Min Zhan; Bing Wu (Journal of Cleaner Production, 2024)

Genomic analysis of hypoxia-tolerant population of the Chinese mitten crab (Eriocheir sinensis) - Feng-yuan Yan; Yuan-feng Xu; Wen-rong Feng; Qing-hong He; Guo-an Hua; Wen-jing Li; Pao Xu; Jun Zhou; Yong-kai Tang (Fish & Shellfish Immunology, 2024)

A molecular mechanism underlies grass carp (Ctenopharyngodon idella) TARBP2 regulating PKR-mediated cell apoptosis - Miao-miao Li; Chang-bai Tao; Mei-feng Li; Chu-xin Wu; Ting-ting Yu; Zhi-qing Feng; Qing-Zhang; Ze-yin Jiang; Hui-ling Mao; Shang-hong Wang; Xiao-wen Xu; Cheng-yu Hu (Fish & Shellfish Immunology, 2024)

Transcriptome analysis of Scylla paramamosain hepatopancreas response to mud crab dicistrovirus-1 infection - Min-Ze Liao; Chang-Hong Cheng; Gui-Ying Li; Hong-Ling Ma; Guang-Xin Liu; Si-Gang Fan; Yi-Qin Deng; Jian-Jun Jiang; Juan Feng; Zhi-Xun Guo (Fish & Shellfish Immunology, 2024)

Preparation of functionalized porous chitin carbon to enhance the H2O2 production and Fe3+ reduction properties of Electro-Fenton cathodes for efficient degradation of RhB - Chengwang Zhao; Wei Li; Jiashuo Hu; Chen Hong; Yi Xing; Hao Wang; Wei Ling; Yijie Wang; Lihui Feng; Weibo Feng; Jiachen Hou; Xinlin Zhai; et al. (Environmental Research, 2024)

Influence of soil pH and organic carbon content on the bioaccessibility of lead and copper in four spiked soils - Jiaqi Cui; Hongbo Li; Yangxiaoxiao Shi; Feng Zhang; Zhineng Hong; Di Fang; Jun Jiang; Yujun Wang; Renkou Xu (Environmental Pollution, 2024)

Near-surface soil hydrothermal response feedbacks landslide activity and mechanism - Xiao Ye; Hong-Hu Zhu; Bing Wu; Feng Tian; Wei Zhang; Xie Hu; Luca Schenato; Alessandro Pasuto; Filippo Catani (Engineering Geology, 2024)

Experimental studies and pore-scale modeling of hydrate dissociation kinetics at different depressurization rates in a cubic hydrate simulator - Chang-Wen Xiao; Xiao-Sen Li; Hong-Feng Lu; Gang Li; Chen-Lu Xu; Rong-Rong Qi; Dong-Hui Xing; Xian Li; Yi-Fan Weng; Lu Yu (Chemical Engineering Journal, 2024)

Asymmetric structural strategy enables efficient MR-TADF emitters with low efficiency roll-off and doping-concentration insensitivity - Zhang-Li Cheng; Jie Li; Hui Wang; Feng Huang; Ying-Chun Cheng; Hao Wu; Xin Xiong; Tong-Yuan Zhang; Jia Yu; Jun Ye; Kai Wang; Xiao-Hong Zhang (Chemical Engineering Journal, 2024)

Exploring the effects of pemetrexed on drug resistance mechanisms in human lung adenocarcinoma and its association with PGRMC1 - Ssu-Yun Wu; En-Chi Liao; Yueh-Feng Wen; Yi-Shiuan Wang; Han Meng; Hsiu-Chuan Chou; Hong-Lin Chan (Chemico-Biological Interactions, 2024)

Changing law of permeability coefficient during compression for reconstituted sandy clays - Meng Ying Gao; Feng Ji; Zhen-Shun Hong; Xiu Song Shi (Marine Georesources & Geotechnology, 2024)

Microbial groups containing alkaline phosphatase accelerate soil phosphate mineralization in two soil patterns with contrasting pH levels - Hui Li; Jitong Lin; Qi Shao; Beibei Zhang; Yunting Wang; Linke Wang; Haojie Feng; Yanhong Lou; Hui Wang; Quangang Yang; Zhongchen Yang; Hongjie Di; et al. (Journal of Soils and Sediments, 2024)

Cynarin inhibits microglia-induced pyroptosis and neuroinflammation via Nrf2/ROS/NLRP3 axis after spinal cord injury - Bin Zhang; Jiasheng Yu; Lei Bao; Dongqian Feng; Yong Qin; Daobo Fan; Xin Hong; Yongyi Chen (Inflammation Research, 2024)

Hohaiivirga grylli gen. nov., sp. nov., a New Member of the Family Methylobacteriaceae, Isolated from Cricket (Gryllus chinensis) - Hong-Chuan Wang; Meng-Han Huang; Dan-Yuan Guo; Wei He; Lu Wang; Zi-Yue Fu; Wen-Jun Li; Ai Hua Zhang; Dao-Feng Zhang (Current Microbiology, 2024)

Crustal anatectic origin of the pegmatitic carbonate rocks in the Proterozoic Highland Complex, Sri Lanka - Ben-Xun Su; Shi-Ying Wang; P. L. Dharmapriya; Jing Wang; Sanjeewa P. K. Malaviarachchi; Kui-Feng Yang; Hong-Rui Fan (Contributions to Mineralogy and Petrology, 2024)

Development and application of turbulent heat flux model for lead-bismuth eutectic based on deep learning - Li-Xia Chen; Chao Yuan; Jun-Long Zhao; Hong-Na Zhang; Xiao-Bin Li; Feng-Chen Li (Annals of Nuclear Energy, 2024)

Conjugated Polymers Based on Carbazole and Tridentate Ligands as the “On-Off-On” Fluorescent Probes for Detection of Ni (II) Ion and Lysine - Yinshuang Chen; Yi Feng; Haoyue Luo; Xinai Chen; Hong Lei; Juhua Feng; Kuan Liu (Journal of Fluorescence, 2024)

Integrated induction of silver resistance determinants and production of extracellular polymeric substances in Cupriavidus metallidurans BS1 in response to silver ions and silver nanoparticles - Jia-Xin Dai; Yanshuang Yu; Le-Xing You; Hong-Lin Zhong; Yuan-Ping Li; Ai-Jun Wang; Jon Chorover; Ren-Wei Feng; Hend A. Alwathnani; Martin Herzberg; Christopher Rensing (Chemosphere, 2024)

An analytical model of longitudinal joints in the segmental lining of shield tunnels with considering geometric nonlinearity - Dong-Lin Feng; Huai-Na Wu; Ren-Peng Chen; Si-Qi Yang; Hong-Zhan Cheng (Tunnelling and Underground Space Technology, 2024)

Hourly effect of atmospheric reactive nitrogen species on the onset of acute ischemic stroke: Insight from the Shanghai Stroke Service System Database - Kun Fang; Lan Hong; Yiran Zhang; Nan Cao; Jialiang Feng; Ming Hu; Qingyan Fu; Yang Zheng; Qundi Yang; Yuzhuo Wang; Jinyitao Wang; Shunyao Wang; et al. (Science of The Total Environment, 2024)

Analytical model for the mitigation of VOC vapor with horizontal permeable reactive barrier in the contaminated site considering non-uniform source - Zhang-Wen Zhu; Shi-Jin Feng; Qi-Teng Zheng; Hong-Xin Chen; Heng Wei (Science of The Total Environment, 2024)

Machine learning for high-precision simulation of dissolved organic matter in sewer: Overcoming data restrictions with generative adversarial networks - Feng Hou; Shuai Liu; Wan-Xin Yin; Li-Li Gan; Hong-Tao Pang; Jia-Qiang Lv; Ying Liu; Hong-Cheng Wang (Science of The Total Environment, 2024)

Biogeography and community assembly of soil fungi from alpine meadows in southwestern China show the importance of climatic selection - Yong Jie Liu; Sai Gong; Yuan Bing Wang; Zhu L. Yang; Wei Hong Hu; Bang Feng (Science of The Total Environment, 2024)

Refracturing shale gas wells in China: Doubling water consumption for enhanced gas recovery - Wenrui Shi; Jianfeng Li; Zisang Huang; Yijiang Feng; Pu Hong; Shaojia Lei; Yi Wu; Jianliang Wang; Meiyu Guo (Science of The Total Environment, 2024)

Review of cathodic electroactive bacteria: Species, properties, applications and electron transfer mechanisms - Xinxin Shi; Yutong Liang; Gang Wen; Stanislav A. Evlashin; Fedor S. Fedorov; Xinyue Ma; Yujie Feng; Junjie Zheng; Yixing Wang; Julian Shi; Yang Liu; Weihuang Zhu; et al. (Science of The Total Environment, 2024)

Combination and summary of ATLAS dark matter searches interpreted in a 2HDM with a pseudo-scalar mediator using 139 fb−1 of s = 13 TeV pp collision data - G. Aad; B. Abbott; K. Abeling; N.J. Abicht; S.H. Abidi; A. Aboulhorma; H. Abramowicz; H. Abreu; Y. Abulaiti; A.C. Abusleme Hoffman; B.S. Acharya; C. Adam Bourdarios; et al. (Science Bulletin, 2024)

FossilMorph: A new tool for fossil automatic measurement and statistical analysis - Wen-Tao Zheng; Zhou-Wei Lou; Ye-Feng Yu; Qing Tang; Xiao-Peng Wang; Xian-Ye Zhao; Hong-Yi Shi; Bin Wan (Palaeoworld, 2024)

Large-sample detection of reservoir impacts on flow regime alteration through improved paired-catchment approach - Xinli Bai; Wenbin Liu; Tingting Wang; Yao Feng; Hong Wang; Zhiyang Lan; Shuyao Guo; Fubao Sun (Journal of Hydrology, 2024)

Unveiling the roles of turbulence characteristics on the degradation of methylene blue by the activation of H2O2 through vortex-based hydrodynamic cavitation under neutral condition - Zhewen Shao; Kexin Xiang; Shuchang Liu; Feng Hong; Ye Gao; Enhong Lei; Jinping Jia; Yingping Huang (Journal of Environmental Chemical Engineering, 2024)

Construction of oxygen-doped g-C3N4/BiOCl (S-scheme) heterojunction: Efficient degradation of tetracycline in wastewater - Yuan Wei; Yu-Bing Liu; Chao Liu; Xin Li; Guang-Hong Zhao; Rong-Hui Liu; Hong-Yu Wang; Yan-Yan Jiang; Yu-Lan Zhang; Yu-Hui Gao; Gao-Feng Shi; Guo-Ying Wang (Journal of Environmental Chemical Engineering, 2024)

Effect of lipoxygenase-catalyzed linoleic acid oxidation and 4-hydroxy-2-nonenal on digestibility and gel properties of myofibrillar protein - Ruifang Feng; Huijuan Zhang; Ning Ding; Huawei Ma; Yongkang Luo; Yuqing Tan; Sutee Wangtueai; Hui Hong (Food Bioscience, 2024)

Caspase-3 interactions with calpain and cathepsin L: Implications for protein stability and quality in fish fillets during postmortem storage - Xiong Xin; Ding Ning; Zhuang Shuai; Dou Peipei; Feng Ruifang; Tan Yuqing; Ma Huawei; Chen Lin; Hong Hui; Luo Yongkang (Food Bioscience, 2024)

Myo-inositol: A potential game-changer in preventing gill cell death and alleviating “gill rot” in grass carp (Ctenopharyngodon idellus) - Jie Chen; Wei-Dan Jiang; Lin Feng; Pei Wu; Yang Liu; Xiao-Wan Jin; Hong-Mei Ren; Jia-Yong Tang; Rui-Nan Zhang; Xiao-Qiu Zhou (Fish & Shellfish Immunology, 2024)

Decontamination promotes the release of incorporated organic contaminants in hair: Novel insights into non-invasive biomonitoring - Rui-Xin Qin; Xue Cao; Shi-Yi Zhang; Hong Li; Bin Tang; Qi-Long Liao; Feng-Shan Cai; Xian-Zhi Peng; Jing Zheng (Environmental Pollution, 2024)

Electrocatalytic coupled biofilter for treating cyclohexanone-containing wastewater: Degradation, mechanism and optimization - Xiuding Shi; Zhi Huang; Lihua Liu; Han Feng; Ruisong Lan; Junming Hong (Environmental Pollution, 2024)

Corrigendum to “Aflatoxin B1 disrupts testicular development via the cell cycle-related Ras/PI3K/Akt signaling in mice and pig” [Environ. Pollut. 329 (2023) 121729] - Fa-Li Zhang; Hao-Hai Ma; Pei-Yu Dong; Zheng-Ning Yuan; Shu-Er Zhang; Ai-Hong Zhao; Huan-Qi Liu; Massimo De Felici; Wei Shen; Xi-Feng Zhang (Environmental Pollution, 2024)

Controlling of irreversible fouling and mechanism in a hybrid ceramic membrane bioreactor (CMBR)-reverse osmosis (RO) process for textile wastewater reclamation - Feng Zhou; Wenyue Wang; Kaiyi Li; Weilong Yang; Jaewon Lee; Bing Xie; Bing Wu; Hongqiang Ren; Seungkwan Hong; Min Zhan (Desalination, 2024)

Overlapping hotspot tracks and melts from diffuse plume materials in the upper mantle generated intraplate seamount groups in the West Pacific - Xun Wei; Guo-Liang Zhang; Ji Zhang; Xue-Fa Shi; Paterno R. Castillo; Yan Zhang; Wan-Feng Zhang; Yi-Gang Xu; Hong-Yan Li; Hui Zhang (Earth and Planetary Science Letters, 2024)

Tailor-made the ultrathin nanosheet and acid site accessibility of mordenite zeolite for carbonylation of dimethyl ether - Feng Chen; Xiao-Bo Feng; Pan Deng; Li-Yun Zhang; Jing-Ping Zhao; Yu-Hui Wang; Bo-Yu Tao; Xiao-Yan Zhao; Jing-Pei Cao; Hong-Cun Bai (Chemical Engineering Journal, 2024)

A comprehensive study on the effects of annular protrusion for cavitation intensification in Venturi tubes - Wei Ding; Feng Hong; Diwen Ying; Yingping Huang; Shah Nawaz Khan; Jinping Jia (Chemical Engineering Journal, 2024)

Composition modulation of electrocatalysts based on 3d transition metal towards high-performance Zn-air batteries - Ya-Fei Guo; Xu Liu; Shao-Jie Yang; Peng-Fei Wang; Zong-Lin Liu; Jun-Hong Zhang; Chun-Sheng Li; Jie Shu; Ting-Feng Yi (Chemical Engineering Journal, 2024)

Nickel single-atom synergistic iron-nitrogen sites for efficient CO2 electroreduction at a wide potential range - Xiao-Chun Yan; Ke-Xin Chen; Guang-Ying Zhang; Meng-Xing Peng; Jia-Ying Ma; Hong-Bing Zang; Hong Dong; Ya Wang; Feng-Ming Zhang (Chemical Engineering Journal, 2024)

Dual-Salt aqueous electrolyte for enhancing Charge-Storage properties of VO2 polymorphic cathodes for Zn-Ion batteries - Jing-Hong Huang; Xu-Feng Luo; Tzu-Yu Kuo; Yu-Hua Lai; Purna Chandra Rath; Chun-Wei Huang; Ming-Hsien Lin; An-Yuan Hou; Ju Li; Yu-Sheng Su; Wen-Wei Wu; Jeng-Kuei Chang (Chemical Engineering Journal, 2024)

Dynamic fluorescent patterns inspired by cuttlefish for anti-counterfeiting applications - Shu-Yu Liang; Yue-Feng Liu; Zhi-Kun Ji; Hong Xia; Hong-Bo Sun (Chemical Engineering Journal, 2024)

Comparative analysis of tracking and behavioral patterns between wild-type and genetically modified fruit flies using computer vision and statistical methods - Fei Ying Lu; Xiang Liu; Hai Feng Su; Shuo Hong Wang (Behavioural Processes, 2024)

A Cysteinyl-tRNA Synthetase Mutation Causes Novel Autosomal-Dominant Inheritance of a Parkinsonism/Spinocerebellar-Ataxia Complex - Han-Kui Liu; Hong-Lin Hao; Hui You; Feng Feng; Xiu-Hong Qi; Xiao-Yan Huang; Bo Hou; Chang-Geng Tian; Han Wang; Huan-Ming Yang; Jian Wang; Rui Wu; et al. (Neuroscience Bulletin, 2024)
This study aimed to identify possible pathogenic genes in a 90-member family with a rare combination of multiple neurodegenerative disease phenotypes, which has not been depicted by the known neurodegenerative disease. We performed physical and neurological examinations with International Rating Scales to assess signs of ataxia, Parkinsonism, and cognitive function, as well as brain magnetic resonance imaging scans with seven sequences. We searched for co-segregations of abnormal repeat-expansion loci, pathogenic variants in known spinocerebellar ataxia-related genes, and novel rare mutations via whole-genome sequencing and linkage analysis. A rare co-segregating missense mutation in the CARS gene was validated by Sanger sequencing and the aminoacylation activity of mutant CARS was measured by spectrophotometric assay. This pedigree presented novel late-onset core characteristics including cerebellar ataxia, Parkinsonism, and pyramidal signs in all nine affected members. Brain magnetic resonance imaging showed cerebellar/pons atrophy, pontine-midline linear hyperintensity, decreased rCBF in the bilateral basal ganglia and cerebellar dentate nucleus, and hypo-intensities of the cerebellar dentate nuclei, basal ganglia, mesencephalic red nuclei, and substantia nigra, all of which suggested neurodegeneration. Whole-genome sequencing identified a novel pathogenic heterozygous mutation (E795V) in the CARS gene, meanwhile, exhibited none of the known repeat-expansions or point mutations in pathogenic genes. Remarkably, this CARS mutation causes a 20% decrease in aminoacylation activity to charge tRNA Cys with L-cysteine in protein synthesis compared with that of the wild type. All family members carrying a heterozygous mutation CARS (E795V) had the same clinical manifestations and neuropathological changes of Parkinsonism and spinocerebellar-ataxia. These findings identify novel pathogenesis of Parkinsonism-spinocerebellar ataxia and provide insights into its genetic architecture.

Semi-synthesis and in vitro anti-cancer effects evaluation of novel xanthohumol derivatives - Xiaolong Sun; Jie Chen; Di Huang; Feng Ding; Long Zhao; Hong-Mei Li; Xiang-Shu Wang; Yu-Xin Zhang; Cheng-Zhu Wu (Molecular Diversity, 2024)

Over-commitment positively predicts hair cortisol concentrations only in nurses with high need for recovery - Xingliang Qi; Huihua Deng; Hong Zhang; Feng Shao; Wenjing Cai; Yapeng Liu (International Archives of Occupational and Environmental Health, 2024)

Association Between the Copper-to-Zinc Ratio and Cardiovascular Disease Among Chinese Adults: A China Multi-ethnic Cohort (CMEC) Study - Yili Shen; Yuxin Hu; Leilei Liu; Jianqin Zhong; Yuxin Zhang; Shenyan Wu; Cheng Chen; Feng Hong (Cardiovascular Toxicology, 2024)