Nitrogen Enrichment Reduces the Diversity of Bacteria and Alters Their Nutrient Strategies in Intertidal Zones - Yuan-Feng Xu; Xu-Meng Dong; Cheng Luo; Shuo-Nan Ma; Ji-Lin Xu; Yong-De Cui (Frontiers in Marine Science, 2022)
Intertidal ecosystems are affected by severe nitrogen (N) pollution as a result of anthropogenic activities, and it is unclear how this may affect intertidal microbial communities, which play critical roles in regulating biogeochemical cycles. To address this gap, we conducted a two-month mesocosm experiment using six targeted concentrations of total N. The findings indicated that N entering seawaters has direct negative effects on the bacterial diversity. Dose dependence was found for the effects of N on bacterial diversity in sediment: low N addition increased the bacterial diversity, but a reduction in bacterial diversity occurred when N exceeded a certain value (≥ 3 mg L−1). Additionally, N enrichment caused clear shifts in bacterial community composition with increases in the relative abundance of Balneola (organic-degrading), Phalacroma mitra (carbohydrate-fermenting), and Bacteroides (phosphorus (P)-solubilizing), and decreases in Leptolyngbya_PPC_6406 (N2-fixing). The increased abundance in P-solubilizing and organic-degrading bacteria and decrease in N-fixing bacteria, combined with the upregulated activity of alkaline phosphatase and downregulation of urease activity, implied that the bacterial assemblage tended to be more effective in P and carbon acquisition but reduced N acquisition. Further path analysis suggested that N had direct effects on bacteria and contributed 50%–100% to the variations in bacterial diversity, whereas environmental changes such as dissolved oxygen and pH played minor roles. Overall, bacteria occurring in sediment were likely more stress-resistant to high N exposure than those occurring in seawater, possibly due to the high buffering capacity of sediment and growth tolerances of bacteria in the sediment. These findings point to the vulnerability of microbes in water systems to increasing global N loading, and that N reduction is needed to combat the loss of microbial diversity.

Efficient de novo assembly and modification of large DNA fragments - Shuangying Jiang; Yuanwei Tang; Liang Xiang; Xinlu Zhu; Zelin Cai; Ling Li; Yingxi Chen; Peishuang Chen; Yuge Feng; Xin Lin; Guoqiang Li; Jafar Sharif; et al. (Science China Life Sciences, 2022)

Production and Evaluation of a Novel Multi-Epitope Bivalent Vaccine Against Echinococcus multilocaularis Metacestode - Runle Li; Mingyuan Xin; Kunmei Liu; Bingwen Hu; Jingwei Ma; Pei Zhou; Lin Feng; Mingquan Pang; Ri-li Ge; Haining Fan; Le Guo; Feng Tang (International Journal of Peptide Research and Therapeutics, 2022)

Interactive effects of tropospheric ozone and blast disease (Magnaporthe oryzae) on different rice genotypes - Muhammad Shahedul Alam; Angeline Wanjiku Maina; Yanru Feng; Lin-Bo Wu; Michael Frei (Environmental Science and Pollution Research, 2022)
Rising tropospheric ozone concentrations can cause rice yield losses and necessitate the breeding of ozone-tolerant rice varieties. However, ozone tolerance should not compromise the resistance to important biotic stresses such as the rice blast disease. Therefore, we investigated the interactive effects of ozone and rice blast disease on nine different rice varieties in an experiment testing an ozone treatment, blast inoculation, and their interaction. Plants were exposed to an ozone concentration of 100 ppb for 7 h per day or ambient air throughout the growth period. Half of the plants were simultaneously infected with rice blast inoculum. Grain yield was significantly reduced in the blast treatment (17%) and ozone treatment (37%), while the combination of both stresses did not further decrease grain yields compared to ozone alone. Similar trends occurred for physiological traits such as vegetation indices, normalized difference vegetation index (NDVI), photochemical reflectance index (PRI), Lichtenthaler index 2 (Lic2), and anthocyanin reflectance index 1 (ARI1), as well as stomatal conductance and lipid peroxidation. Ozone exposure mitigated the formation of visible blast symptoms, while blast inoculation did not significantly affect visible ozone symptoms. Although different genotypes showed contrasting responses to the two types of stresses, no systematic pattern was observed regarding synergies or trade-offs under the two types of stresses. Therefore, we conclude that despite the similarities in physiological stress responses to ozone and blast, the tolerance to these stresses does not appear to be genetically linked in rice.

Changes of network structure and water distribution in sludge with the stratified extraction of extracellular polymeric substances - Feng Lin; Bingyun Li (Environmental Science and Pollution Research, 2022)

Use of the MaxEnt model to predict changes in sloth bear (Melursus ursinus) habitats in the Gandaki River Basin, Nepal - Raju Rai; Yi-li Zhang; Zhao-feng Wang; Basanta Paudel; Lin-shan Liu; Mohan Kumar Rai; Narendra Raj Khanal (Journal of Mountain Science, 2022)

Effects of dietary nucleotides on growth performance, immune response, intestinal morphology and disease resistance of juvenile largemouth bass, Micropterus salmoides - Xiao‐chun Chen; Xiao‐quan Huang; Yi‐wen Tang; Lei Zhang; Feng Lin (Journal of Fish Biology, 2022)
An 8 week feeding trial was carried out to investigate the effects of dietary nucleotides on growth performance, intestinal morphology, immune response and disease resistance of juvenile largemouth bass, Micropterus salmoides . Five grades of dietary nucleotide levels were designed as 0, 0.2, 0.4, 0.8 and 1.2 g kg −1 , respectively. Each group had 3 replicates, with 40 fish in each replicate. After the feeding experiment, 15 fish from each tank were infected with Aeromonas hydrophila for 14 days. The results indicated that fish fed the diets containing 0.4, 0.8 and 1.2 g kg −1 nucleotides had higher growth performance and feed utilization than those fed the control diet. Nonetheless, there were no significant differences in survival between all the groups, although fish fed the diets with all‐level nucleotides obtained higher survival than those fed the control diet. Dietary nucleotides significantly affected the superoxide dismutase, acid phosphatase and catalase activities in serum but not the malondialdehyde content. Fish fed the 0.4 g kg −1 nucleotide diets had the highest fold height, enterocyte height and muscular layer thickness significantly. The average mortality of largemouth bass infected with A. hydrophila was significantly influenced by dietary nucleotides. The mortality was significantly higher in the control group (91.11%) and 0.02% nucleotide group (73.11%) followed by the other groups and lowest in the 0.8 g kg −1 nucleotide group. In summary, dietary 0.4–0.8 g kg −1 nucleotides promoted growth performance, enhanced immunity and improved intestinal morphology and disease resistance of largemouth bass.

Biochemical and structural characterization of the cyanophage‐encoded phosphate‐binding protein: implications for enhanced phosphate uptake of infected cyanobacteria - Fangxin Zhao; Xingqin Lin; Kun Cai; YongLiang Jiang; Tianchi Ni; Yue Chen; Jianrong Feng; Shangyu Dang; Cong‐Zhao Zhou; Qinglu Zeng (Environmental Microbiology, 2022)
Summary To acquire phosphorus, cyanobacteria use the typical bacterial ABC‐type phosphate transporter, which is composed of a periplasmic high‐affinity phosphate‐binding protein PstS and a channel formed by two transmembrane proteins PstC and PstA. A putative pstS gene was identified in the genomes of cyanophages that infect the unicellular marine cyanobacteria Prochlorococcus and Synechococcus . However, it has not been determined whether the cyanophage PstS protein is functional during infection to enhance the phosphate uptake rate of host cells. Here we showed that the cyanophage P‐SSM2 PstS protein was abundant in the infected Prochlorococcus NATL2A cells and the host phosphate uptake rate was enhanced after infection. This is consistent with our biochemical and structural analyses showing that the phage PstS protein is indeed a high‐affinity phosphate‐binding protein. We further modelled the complex structure of phage PstS with host PstCA and revealed three putative interfaces that may facilitate the formation of a chimeric ABC transporter. Our results provide insights into the molecular mechanism by which cyanophages enhance the phosphate uptake rate of cyanobacteria. Phosphate acquisition by infected bacteria can increase the phosphorus contents of released cellular debris and virus particles, which together constitute a significant proportion of the marine dissolved organic phosphorus pool.

Discovery of the non‐cosmopolitan lineages in Candidatus Thermoprofundales - Yi‐Fan Liu; Liu Yang; Zhong‐Lin Liu; Jing Chen; Bo Fang; Lei Zhou; Jin‐Feng Liu; Shi‐Zhong Yang; Ji‐Dong Gu; Bo‐Zhong Mu (Environmental Microbiology, 2022)
Summary The recently proposed order Candidatus Thermoprofundales, currently containing only one family‐level lineage Marine Benthic Group‐D (MBG‐D), is distributed in global subsurface ecosystems and ecologically important, but its diversity, evolution and metabolism remain largely unknown. Here we described two novel family‐level specialized lineages in Ca . Thermoprofundales, JdFR‐43 and HyVt, which are restricted to specific biotopes (primarily in marine hydrothermal vents and occasionally in oil reservoirs and hot springs) in contrast to the cosmopolitan lineage MBG‐D. The comparative genomics revealed that the specialized lineages have streamlined genomes, higher GC contents, enriched genes associated with nucleotide biosynthesis, ribosome biogenesis and DNA repair and additional thermostable aminopeptidases, enabling them to adapt to high‐temperature habitats such as marine hydrothermal vents, deep subsurface oil reservoirs and hot springs. On the contrary, the unique metabolic traits of the cosmopolitan MBG‐D, motility, glycolysis, butanoate metabolism, secondary metabolites production and additional genes for specific peptides and carbohydrates degradation potentially enhance its response to environmental change. Substrate preference is found for most MAGs across all lineages with the ability to utilize both polysaccharides (chitin and starch) and proteinaceous substances, whereas JdFR‐43 members from oil reservoirs can only utilize proteins. These results expand the diversity of C a . Thermoprofundales significantly and further improve our understandings of the adaptations of C a . Thermoprofundales to various environments.

Effects of micronized bamboo powder on growth performance, serum biochemical indexes, cecal chyme microflora and metabolism of broilers aged 1–22 days - Fawen Dai; Tao Lin; Lumin Cheng; Jian Wang; Jianjun Zuo; Dingyuan Feng (Tropical Animal Health and Production, 2022)
Adding insoluble fiber to diet of broilers has been reported to improve intestinal health and promote growth performance. Bamboo powder is a cheap raw material with rich insoluble fiber. This study aims to explore the effects of feeding micronized bamboo powder (MBP) on growth performance, serum biochemical indexes, intestinal microflora, and metabolism of broilers. A total of 1440 1-day-old slow-growing Ephedra chickens were randomly divided into three groups considering gender and body weight: (1) Group D: feeding with basal diet without antibiotics; (2) Group E: feeding with basal diet supplemented with 5% rice bran (RB); (3) Group F: feeding with basal diet supplemented with 1% MBP. Each group involved 8 replicates feeding for 22 days, with 60 chickens per replicate. Various indexes were detected. For the growth performance, the weight gain and feed consumption ratio (G: F) of Group F supplemented with MBP is 0.57 ± 0.04, which is significantly higher than that of E group supplemented with RB (0.52 ± 0.01, P < 0.05). For the serum biochemical indexes, the glutathione peroxidase activity in Group F is significantly higher than that of Group D, while the malondialdehyde content is significantly lower than that of Group D and Group E ( P < 0.05 for all). The fresh cecal chyme is taken for determination. In Group F, the α diversity index Faith_pd is significantly lower in Group F than that of Group D. The microorganism species in cecal chyme of Group F and Group E are also different. The metabolic pathways of Group F, mainly in fatty acid metabolism, amino acid metabolism and intestinal immune IgA production, were different from those of Group D and Group E. Adding 1% MBP to broiler diet can enhance the anti-oxidant capacity, improve chyme microflora, regulate the metabolism pathways responsible for intestinal fatty acids, amino acids, and immunity.

Industrial scale-up of tissue-cultured Dracaena cambodiana Pierre ex Gagnep - Feng Zheng; Yuping Xiong; Kunlin Wu; Jaime A. Teixeira da Silva; Songjun Zeng; Xuemao Lin; Guohua Ma (Trees, 2022)

Identification of the Largest SCA36 Pedigree in Asia: with Multimodel Neuroimaging Evaluation for the First Time - Yue Xie; Zhao Chen; Zhe Long; Rui-Ting Chen; Yi-Zheng Jiang; Ming-Jie Liu; Lin-Liu Peng; Hui-Rong Peng; Na Wan; Guangdong Zou; Chun-Rong Wang; Yu-Ting Shi; et al. (The Cerebellum, 2022)

Correction to: Baicalin Attenuates Ketamine-Induced Neurotoxicity in the Developing Rats: Involvement of PI3K/Akt and CREB/BDNF/Bcl-2 Pathways - Daiying Zuo; Li Lin; Yumiao Liu; Chengna Wang; Jingwen Xu; Feng Sun; Lin Li; Zengqiang Li; Yingliang Wu (Neurotoxicity Research, 2022)

Rainfall Variability Index (RVI) analysis of dry spells in Malaysia - Yuk Feng Huang; Ali Najah Ahmed; Jing Lin Ng; Kok Weng Tan; Pavitra Kumar; Ahmed El-Shafie (Natural Hazards, 2022)

A Combined Proteomics and Metabolomics Profiling to Investigate the Genetic Heterogeneity of Autistic Children - Liming Shen; Huajie Zhang; Jing Lin; Yan Gao; Margy Chen; Naseer Ullah Khan; Xiaoxiao Tang; Qi Hong; Chengyun Feng; Yuxi Zhao; Xueshan Cao (Molecular Neurobiology, 2022)

Comprehensive Transcriptome Analysis of Gonadal and Somatic Tissues for Identification of Sex-Related Genes in the Largemouth Bass Micropterus salmoides - Wen-Zhi Guan; Kai Jiang; Xing-Lin Lai; Yao-Ting Dong; Gao-Feng Qiu (Marine Biotechnology, 2022)

Determination of glyphosate, aminomethylphosphonic acid, and glufosinate in river water and sediments using microwave-assisted rapid derivatization and LC–MS/MS - Jyun-Fong Lin; Fang-Chih Chang; Jenn-Feng Sheen (Environmental Science and Pollution Research, 2022)

Heavy metal-induced lipogenic gene aberration, lipid dysregulation and obesogenic effect: a review - Yang Zhou; Frank Peprah Addai; Xinshuang Zhang; Yuelin Liu; Yinfeng Wang; Feng Lin; Alex Tuffour; Jie Gu; Guangxiang Liu; Haifeng Shi (Environmental Chemistry Letters, 2022)

Investigation on long-term progressive deformation of engineering slope based on comprehensive monitoring - Shi-shu Zhang; Song-feng Guo; Sheng-wen Qi; Feng-jiao Tang; Jin-shan Hu; Xiao-ping Zhao; Cong-yan Ran; Xin Wang; Yu Zou; Xiao-lin Huang; Bo-wen Zheng; Ning Liang (Journal of Mountain Science, 2022)

Flow-slide characteristics and failure mechanism of shallow landslides in granite residual soil under heavy rainfall - Hui-lin Bai; Wen-kai Feng; Shuang-quan Li; Long-zhen Ye; Zhong-teng Wu; Rui Hu; Hong-chuan Dai; Yun-peng Hu; Xiao-yu Yi; Peng-cheng Deng (Journal of Mountain Science, 2022)

Prognostic implication and immunotherapy response prediction of a costimulatory molecule signature in kidney renal clear cell carcinoma - Gaoteng Lin; Yuanyuan Yang; Qingfu Feng; Fangfang Zhan; Chuangxin Sun; Yuanjie Niu; Gang Li (Immunogenetics, 2022)

Comparison of different inversion methods of D-T2 two-dimensional nuclear magnetic resonance logging and applicability analysis - Cheng-Lin Li; Mao-Jin Tan; Ke-Wen Wang; Feng Zhou; Ying-Ming Liu; Hai-Tao Zhang; Li-Zhi Xiao (Applied Geophysics, 2022)

Massive Heat Shock Protein 70 Genes Expansion and Transcriptional Signatures Uncover Hard Clam Adaptations to Heat and Hypoxia - Zhi Hu; Hao Song; Jie Feng; Cong Zhou; Mei-Jie Yang; Pu Shi; Zheng-Lin Yu; Yong-Ren Li; Yong-Jun Guo; Hai-Zhou Li; Tao Zhang (Frontiers in Marine Science, 2022)
Heat shock protein 70 (HSP70) members participate in a wide range of housekeeping and stress-related activities in eukaryotic cells. In marine ecosystems, bivalves encounter abiotic stresses, including high temperatures and low dissolved oxygen. Here, 133 MmHSP70 genes were identified through combined methods including Blastp, HMM and manual filtration, based on the whole Mercenaria mercenaria genome. The MmHSP70 genes were unevenly distributed, and 41 genes (33.08%) were located on Chr 7. Phylogenetic analyses indicated that the MmHSP70 gene family mainly consisted of two clusters and the Hspa12 subfamily underwent lineage-specific expansion. A high-density collinear gene block was observed between M. mercenaria Chr 7 and Cyclina sinensis Chr 14. Tandem duplication MmHSP70 gene pairs experienced different levels of purifying selection, which could be an important source of sequence and functional constraints. MmHSP70 genes showed tissue-specific and stress-specific expression. Most tandem duplication HSP70 gene pairs had high expression under hypoxia stress. HSP70 B2 tandem duplication gene pairs showed significantly increased expression under heat plus severe hypoxia stress. This study provided a comprehensive understanding of the MmHSP70 gene family in the M. mercenaria and laid a significant foundation for further studies on the functional characteristics of MmHSP70 genes during exposure to heat and hypoxia stress.

Entrainment of Astrocytic and Neuronal Ca2+ Population Dynamics During Information Processing of Working Memory in Mice - Zhu Lin; Feng You; Ting Li; Yijia Feng; Xinyue Zhao; Jingjing Yang; Zhimo Yao; Ying Gao; Jiang-Fan Chen (Neuroscience Bulletin, 2022)

Metabolic tuning of a stable microbial community in the surface oligotrophic Indian Ocean revealed by integrated meta-omics - Zhang-Xian Xie; Ke-Qiang Yan; Ling-Fen Kong; Ying-Bao Gai; Tao Jin; Yan-Bin He; Ya-Yu Wang; Feng Chen; Lin Lin; Zhi-Long Lin; Hong-Kai Xu; Zong-Ze Shao; et al. (Marine Life Science & Technology, 2022)
Understanding the mechanisms, structuring microbial communities in oligotrophic ocean surface waters remains a major ecological endeavor. Functional redundancy and metabolic tuning are two mechanisms that have been proposed to shape microbial response to environmental forcing. However, little is known about their roles in the oligotrophic surface ocean due to less integrative characterization of community taxonomy and function. Here, we applied an integrated meta-omics-based approach, from genes to proteins, to investigate the microbial community of the oligotrophic northern Indian Ocean. Insignificant spatial variabilities of both genomic and proteomic compositions indicated a stable microbial community that was dominated by Prochlorococcus , Synechococcus , and SAR11. However, fine tuning of some metabolic functions that are mainly driven by salinity and temperature was observed. Intriguingly, a tuning divergence occurred between metabolic potential and activity in response to different environmental perturbations. Our results indicate that metabolic tuning is an important mechanism for sustaining the stability of microbial communities in oligotrophic oceans. In addition, integrated meta-omics provides a powerful tool to comprehensively understand microbial behavior and function in the ocean.

Poor evidence for host-dependent regular RNA editing in the transcriptome of SARS-CoV-2 - Jinbao Zong; Yanping Zhang; Fenfen Guo; Changyuan Wang; Hong Li; Gaoyang Lin; Wenqing Jiang; Xiaoping Song; Xiufang Zhang; Feng Huang; Min Qi; Xin Zheng (Journal of Applied Genetics, 2022)

Development of a reverse transcription-loop mediated isothermal amplification assay for detection of wisteria vein mosaic virus - Mi-Chi Yao; Peng-Xiang Zhu; Qin-Qin Zhang; Qi-Ping Zhang; Zhao-Lin Ji; Feng Zhu (European Journal of Plant Pathology, 2022)

An implementation framework of blockchain-based hazardous waste transfer management system - Guanghan Song; Yujie Lu; Haibo Feng; Han Lin; Yang Zheng (Environmental Science and Pollution Research, 2022)

A coupling methodology of the analytic hierarchy process and entropy weight theory for assessing coastal water quality - Kai Xiao; Joseph Tamborski; Xuejing Wang; Xiaobo Feng; Sichen Wang; Qianqian Wang; Debei Lin; Hailong Li (Environmental Science and Pollution Research, 2022)

Deformation characteristics and thresholds of the Tanjiawan landslide in the Three Gorges Reservoir Area, China - Fu-ling Zhang; Mao-lin Deng; Qing-lin Yi; Shu-qiang Lu; Wei-jun Zheng; Hai-feng Huang; Xing Zhu (Journal of Mountain Science, 2022)

Integrated Berth and Crane Scheduling Problem Considering Crane Coverage in Multi-Terminal Tidal Ports under Uncertainty - Meixian Jiang; Jian Zhou; Jiajia Feng; Lin Zhou; Fangzheng Ma; Guanghua Wu (Journal of Marine Science and Engineering, 2022)
In this work, we study the integrated berth and crane scheduling problem in a tidal port with multiple terminals, considering the uncertainties, tides, maximum coverage of cranes and interference between cranes. For coping with the uncertainties, a certain number of randomly generated samples are used to evaluate the solutions, and slack variables are introduced to reduce the impact caused by the variation in vessel arrival and crane operational efficiency. A novel nonlinear mixed integer programming model is first formulated for the problem to minimize the sum of expectation and variance of costs under all samples. An improved adaptive genetic algorithm, combining a simulated annealing mechanism and greedy construction strategy, is developed and implemented by MATLAB. The feasibility and validity of the algorithm and the benefits of multi-terminal collaborative scheduling strategy under uncertainty are evaluated through numerical experiments. The results show that the algorithm can obtain feasible scheduling solutions with higher quality. Compared to the strategy that considers either the uncertainty or the multi-terminal collaborative mechanism, the resulting solution considering both can effectively reduce the cost and improve the competitiveness of the port.

A biosurfactant-producing yeast Rhodotorula sp.CC01 utilizing landfill leachate as nitrogen source and its broad degradation spectra of petroleum hydrocarbons - Xiaoyun Lin; Hanghai Zhou; Feng Zeng; Lijia Jiang; Edidiong Okokon Atakpa; Gen Chen; Chunfang Zhang; Qinglin Xie (World Journal of Microbiology and Biotechnology, 2022)

Dissecting the Neural Circuitry for Pain Modulation and Chronic Pain: Insights from Optogenetics - Fang Guo; Yu Du; Feng-Hui Qu; Shi-Da Lin; Zhong Chen; Shi-Hong Zhang (Neuroscience Bulletin, 2022)
Pain is an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. The processing of pain involves complicated modulation at the levels of the periphery, spinal cord, and brain. The pathogenesis of chronic pain is still not fully understood, which makes the clinical treatment challenging. Optogenetics, which combines optical and genetic technologies, can precisely intervene in the activity of specific groups of neurons and elements of the related circuits. Taking advantage of optogenetics, researchers have achieved a body of new findings that shed light on the cellular and circuit mechanisms of pain transmission, pain modulation, and chronic pain both in the periphery and the central nervous system. In this review, we summarize recent findings in pain research using optogenetic approaches and discuss their significance in understanding the pathogenesis of chronic pain.

Heat Shock Procedure Affects Cell Division-Associated Genes in Gynogenetic Manipulation - Fan Yu; Jian-Lin Li; Wen-Rong Feng; Yong-Kai Tang; Sheng-Yan Su; Pao Xu; Huan Zhong (Marine Biotechnology, 2022)

Duration of Induced Metallothionein is a Critical Factor in the Cadmium-Resistance Among Goldfish (Carassius auratus) and Common Carp (Cyprinus carpio) - Feng Ming Chang; Chia Hao Lin; Su Mei Wu (Bulletin of Environmental Contamination and Toxicology, 2022)

Production of sesquiterpene patchoulol in mitochondrion-engineered Saccharomyces cerevisiae - Xin-Yi Tao; Yang-Chen Lin; Feng-Qing Wang; Qing-Hai Liu; Yu-Shu Ma; Min Liu; Dong-Zhi Wei (Biotechnology Letters, 2022)

An extended Human Connectome Project multimodal parcellation atlas of the human cortex and subcortical areas - Chu-Chung Huang; Edmund T. Rolls; Jianfeng Feng; Ching-Po Lin (Brain Structure and Function, 2022)

Road performance and microscopic action mechanism of low liquid limit silt solidified by AT curing agent - Jin Chang; Jian-Qing Jiang; Ming Lei; Shi-Lin Luo; Guang-Feng He; Jia-Yi Lin (Arabian Journal of Geosciences, 2022)

Preparation and In Vitro and In Vivo Evaluation of a Testosterone Film Forming Gel for the Treatment of Hypoactive Sexual Desire Disorder in Women - Jia Zeng; Tan-Fang Xie; Ting Huang; Fang Li; Zhi-Ping Wang; Ling-Lin Feng (AAPS PharmSciTech, 2022)

Micro-/Meso-Scale Distinction and Horizontal Migration of Tintinnid (Ciliophora: Tintinnida) Assemblages in Three Regions Around the North Pacific Ocean - Meiping Feng; Shiquan Lin; Wuchang Zhang; Chunsheng Wang; Hongbin Liu; Shunyan Cheung; Haibo Li; Michael R. Stukel; John Paul Irving; Na Li (Frontiers in Marine Science, 2022)
We explored the relationships among different tintinnid populations on micro-, meso-, and basin-scales from three regions across the Pacific Ocean, including the Costa Rica Dome (CRD) in the Eastern Pacific Ocean, the Celebes Sea (CS), and the Tokara Strait (TS) in the Western Pacific Ocean. We quantified the species occurrence, vertical and biogeographic distribution patterns, and morphological parameters of tintinnid assemblages. A total of 46 tintinnid species were observed, with more than half (63.0%) in common among the three areas, accounting for 97.1% of the total abundances. The numerically abundant forms remained more or less the same set of species in the three areas. However, community structure analyses, in terms of species, lorica oral diameter (LOD) size classes, and genera, revealed clear distinctions among different regions, as well as among different water depths. A Lagrangian simulation of passive dispersal in ocean currents across the Pacific Ocean, supported the hypothesis that greater similarity between tintinnid populations in the CS and TS (relative to CRD), was related to ocean circulation linkages between the populations. A latitudinal decline of tintinnid species richness was observed, mainly as a result of a decline of redundant species and warm-water species in colder areas. These data provide information unique insight into population variability of microzooplankton communities on micro- to meso- and even large scales in the world oceans.

Effect of High-Pressure Treatment on Blue Marlin ( Makaira nigricans ) Quality During Storage - Yi-Chen Lee; Hsien-Feng Kung; Shao-Lan Chen; Chung-Saint Lin; Chun-Yung Huang; Osamu Arakawa; Chih-Hua Tseng; Yung-Hsiang Tsai (Journal of Aquatic Food Product Technology, 2022)

Structural and Functional Improvements of Coastal Ecosystem Based on Artificial Oyster Reef Construction in the Bohai Sea, China - Xu Wang; Jie Feng; Chenggang Lin; Hui Liu; Muyan Chen; Yunling Zhang (Frontiers in Marine Science, 2022)
Oyster reefs are gaining more and more attention in marine ranching and coastal ecosystem restoration, but tremendous knowledge gaps still exist. In this study, we developed trophic models for the established artificial oyster reef (EAOR), newly deployed artificial oyster reef (NAOR), and non-reef bare substratum (NBS) ecosystems located in the Bay of Xiangyun, Bohai Sea, China, to assess the benefits of artificial oyster reef construction and to characterize the unique role of these reefs in coastal management. The analysis showed that the EAOR and NAOR ecosystems were similar to each other, but both were greatly different than the NBS ecosystem. Reefs showed greater “ecological size” and stronger top-down effects compared to the bare area. The ecosystems were not yet mature, but the EAOR and NAOR ecosystems had more complicated trophic relationships, greater potential to withstand perturbations, and higher biological carrying capacities of commercial organisms compared to the NBS ecosystem. These results demonstrated that artificial oyster reef construction resulted in great advantages to the ecosystem. For example, oysters became the structuring functional group and played a critical role in the trophic structure of the reef areas. The phytoplankton/detritus-oysters-carnivorous macrobenthos pathway developed and became dominant in these areas, thereby contributing to highly efficient secondary production. The ratios of total primary production/total respiration were < 1, indicating that the reef ecosystems responded effectively to nutrient inputs from adjacent ecosystems. We speculate that water exchange might be a critical factor influencing the maintenance of the system. Long-term monitoring of the EAOR and NAOR should be implemented for oyster protection and to assess the need to manipulate carnivorous macrobenthos to keep the systems in balance. Results of this study could benefit the restoration, exploitation, and management of oyster reefs. Further studies should take the adjacent ecosystems and anthropogenic activities into account.

Exosomes Derived from lncRNA TCTN2-Modified Mesenchymal Stem Cells Improve Spinal Cord Injury by miR-329-3p/IGF1R Axis - Jian Liu; Mingxia Lin; Feng Qiao; Chenghua Zhang (Journal of Molecular Neuroscience, 2022)

Application of Soil and Water Assessment Tool (SWAT) to evaluate the fates of nitrogenous fertilizer in subtropical mountainous watershed tea farms - Guan-Zhou Lin; Shao-Yiu Hsu; Chia-Chun Ho; Chi-Feng Chen; Jr-Chuan Huang; Tsung-Yu Lee (Environmental Monitoring and Assessment, 2022)

Enhancement of oral bioavailability and anti-hyperuricemic activity of aloe emodin via novel Soluplus®—glycyrrhizic acid mixed micelle system - Feng Shi; Lin Chen; Yaping Wang; Jing Liu; Michael Adu-Frimpong; Hao Ji; Elmurat Toreniyazov; Qilong Wang; Jiangnan Yu; Ximing Xu (Drug Delivery and Translational Research, 2022)

A bi-scale assessing framework for aesthetic ecosystem services of villages in a world heritage site - Yin-ping Ding; Zhi-lin Liu; Yuan-mei Jiao; Qiu-e Xu; Kan-feng Zhang; Cheng-jing Liu; Fan Chen (Journal of Mountain Science, 2022)

Anti-proliferative cassane-type diterpenoids from the seeds of Caesalpinia minax - Yunshao Xu; Wei Shi; Lu Feng; Jun Cao; Zheling Feng; Qingwen Zhang; Jinjian Lu; Yang Ye; Ligen Lin (Natural Product Research, 2022)

Seasonal Variation of Food Web Structure and Stability of a Typical Artificial Reef Ecosystem in Bohai Sea, China - Shengpeng Li; Ruyue Wang; Yueming Jiang; Yanyu Li; Lin Zhu; Jianfeng Feng (Frontiers in Marine Science, 2022)
The last 30 years have witnessed the degradation and loss of function in the ecosystem of the Bohai Sea, China. Great efforts, such as artificial reefs, have been used to restore the ecosystem of the Bohai Sea in recent years. In this study, we examined the seasonal variation of food webs in artificial reefs of Juehua Island by the Ecopath model. Results showed that the number of species, range of trophic level, energy cycle proportion, energy complexity, nutrition transfer efficiency, and ecosystem maturity have increased from summer to autumn. However, the food web stability of artificial reefs has no obvious change from summer to autumn. Loop analysis revealed that the heaviest feedback loops are the interactions among benthos, zooplankton, and phytoplankton, and the predator-prey negative interaction strength between zooplankton and phytoplankton dominated the stability of the artificial reef, whether in summer or autumn. This study suggests that stability is a more robust indicator for ecosystem assessment and could provide useful information in future restoration plans of the marine ecosystem.

Oxygen Metabolism-induced Stress Response Underlies Heart–brain Interaction Governing Human Consciousness-breaking and Attention - Xiao-Juan Xue; Rui Su; Ze-Feng Li; Xiao-Ou Bu; Peng Dang; Si-Fang Yu; Zhi-Xin Wang; Dong-Mei Chen; Tong-Ao Zeng; Ming Liu; Hai-Lin Ma; De-Long Zhang (Neuroscience Bulletin, 2022)

Ameliorating Effect of Umbilical Cord Mesenchymal Stem Cells in a Human Induced Pluripotent Stem Cell Model of Dravet Syndrome - Huifang Zhao; Shuai Li; Lang He; Feng Tang; Xiaobo Han; Weiyue Deng; Zuoxian Lin; Rongqi Huang; Zhiyuan Li (Molecular Neurobiology, 2022)

Identification and bioinformatics analysis of differentially expressed milk exosomal microRNAs in milk exosomes of heat-stressed Holstein cows - Yue Wang; Jian Fang; Han-Fang Zeng; Ji-Feng Zhong; Hui-Xia Li; Kun-Lin Chen (Functional & Integrative Genomics, 2022)

Improving the Nowcasting of Strong Convection by Assimilating Both Wind and Reflectivity Observations of Phased Array Radar: A Case Study - Xiaoxia Lin; Yerong Feng; Daosheng Xu; Yuntao Jian; Fei Huang; Jincan Huang (Journal of Meteorological Research, 2022)

Beryllium-7 and Lead-210 are Associated with an Increase in the Arctic Oscillation: Evidence from Atmospheric Aerosols in a Remote Tropical Region in East Asia - Xiaoxia Chen; Wuhui Lin; Xianwen He; Liangliang Feng; Kuo-Ying Wang (Asia-Pacific Journal of Atmospheric Sciences, 2022)
The Arctic Oscillation (AO) accounts for a large fraction of recent decadal climate trends in Northern Hemisphere (NH) high latitudes. In East Asia, an elevated AO index (AOI) was associated with warmer temperatures in middle- to high-latitude regions, colder temperatures over low-latitude regions, and elevated ozone intrusion from the stratosphere. Elevated beryllium-7 ( 7 Be) is produced in the stratosphere. Few studies have discussed the relationship between 7 Be and the AO. Here, we identify the AO signature in 7 Be and lead (Pb)-210 observed at a tropical ambient monitoring site in Nanning (22.8°N, 108.5°E) during the December 2014–December 2017 period. Our results show that the 7 Be and 210 Pb concentrations are positively and significantly correlated with the AOI ( P 7 Be and 210 Pb are associated with an increase in the AOI, reflecting air masses originating from NH high latitudes and vertically from the high-latitude upper troposphere and lower stratosphere regions to tropical latitudes in East Asia. These results have been verified with ozonesonde data without seasonality and with two meteorological data sets. Our results are also confirmed by observational data over the Pacific regions. We conclude that the AO exerts impacts over the tropical regions in East Asia, and 7 Be can be used as a tracer to track the impacts of the AO.

Pathogenicity and genome-wide sequence analysis reveals relationships between soybean mosaic virus strains - Le Gao; Yueying Wu; Jie An; Wenxuan Huang; Xinlei Liu; Yongguo Xue; Xiaoyan Luan; Feng Lin; Lianjun Sun (Archives of Virology, 2022)

3D geomechanics modeling of Indonesia B oilfield and its application in wellbore stability - Wenjun Cai; Jingen Deng; Yongcun Feng; Hai Lin; Yanguang Yuan; Dongdong Liu (Arabian Journal of Geosciences, 2022)

A Method for Reservoir Effectiveness Evaluations of Altered Igneous Reservoirs based on Logging data: A Case Study of the Nanpu Structure in Eastern China - Weibiao Xie; Zhaowei Si; Feng Xu; Fawu Lin; Chaoguo Tian (Arabian Journal of Geosciences, 2022)

Molecular Identification of Species Diversity Using Pelagic Fish Eggs in Spring and Late Autumn-Winter in the Eastern Beibu Gulf, China - Gang Hou; Yanying Chen; Jinrun Wang; Chuanhao Pan; Jianbin Lin; Bo Feng; Hui Zhang (Frontiers in Marine Science, 2022)
The Beibu Gulf is considered as one of China’s four major fishing grounds, although the substantial overexploitation of fisheries has led to the collapse of many fish stocks, and to changes to spawning grounds in recent decades. Classifying fish eggs is an important way to monitor the recruitment process and identify the spawning sites of fish. However, the lack of a basis for morphological identification and difficulties in correctly identifying fish eggs based on morphological characteristics has limited scientific studies. In the present study, we identified fish eggs using molecular detection of cytochrome c oxidase subunit I and cytochrome b fragments. Ichthyoplankton surveys were conducted in the spring and late autumn–winter of 2020 in the eastern Beibu Gulf. Among the DNA extracted from the 873 chosen fish eggs, we successfully obtained 541 high-quality cytochrome c oxidase subunit I sequences and 41 high-quality cytochrome b sequences. We successfully identified 212 fish eggs (36.4%) from 32 species; 291 eggs (50.0%) showed ambiguous species delimitation, and 79 eggs (13.6%) could not be identified. Among the identified species, we found 25 species in spring and 25 species in late autumn–winter, out of which 18 species occurred in both seasons. We also obtained high resolution photographs of fish eggs at the species level for further morphological analysis and identification. The present study confirms the efficacy of using molecular methods to identify fish species from eggs and provides valuable information for protecting the spawning ground of economically valuable fish and for managing fishery resources.

Research on hoop capacity of composite foundation of discarded rubber tires - Feng-Chi Wang; Jun Li; Zhen-Huan Lin; Pei-Pei Tian; Han-Yu Zhao (European Journal of Environmental and Civil Engineering, 2022)

Mesozoic mafic dykes in the North China Craton: magmatic evolution and implications for gold mineralization - Chao Li; Lin Li; Sheng-Rong Li; M. Santosh; Jun-Feng Shen (International Geology Review, 2022)

Biochanin A as an α-hemolysin inhibitor for combating methicillin-resistant Staphylococcus aureus infection - Jiaxuan Feng; Dazhong Sun; Li Wang; Xueting Li; Jiyu Guan; Lin Wei; Donghui Yue; Xingye Wang; Yicheng Zhao; Haimiao Yang; Wu Song; Bingmei Wang (World Journal of Microbiology and Biotechnology, 2022)

Phylogeographic pattern of a cryptoviviparous mangrove, Aegiceras corniculatum, in the Indo-West Pacific, provides insights for conservation actions - Achyut Kumar Banerjee; Hui Feng; Yuting Lin; Zhuangwei Hou; Weixi Li; Huiyu Shao; Zida Luo; Wuxia Guo; Yelin Huang (Planta, 2022)

β-Catenin Deletion in Regional Neural Progenitors Leads to Congenital Hydrocephalus in Mice - Lin Ma; Yanhua Du; Xiangjie Xu; Hexi Feng; Yi Hui; Nan Li; Guanyu Jiang; Xiaoqing Zhang; Xiaocui Li; Ling Liu (Neuroscience Bulletin, 2022)

Effect of Sodium Salicylate on Calcium Currents and Exocytosis in Cochlear Inner Hair Cells: Implications for Tinnitus Generation - Ting Fan; Meng-Ya Xiang; Ruo-Qiao Zhou; Wen Li; Li-Qin Wang; Peng-Fei Guan; Geng-Lin Li; Yun-Feng Wang; Jian Li (Neuroscience Bulletin, 2022)

Correction to: Pharmacological stimulation of sigma-1 receptor promotes activation of astrocyte via ERK1/2 and GSK3β signaling pathway - Yun Wang; Hua-feng Jiang; Jing Ni; Lin Guo (Naunyn-Schmiedeberg's Archives of Pharmacology, 2022)

An evaluation of various data pre-processing techniques with machine learning models for water level prediction - Ervin Shan Khai Tiu; Yuk Feng Huang; Jing Lin Ng; Nouar AlDahoul; Ali Najah Ahmed; Ahmed Elshafie (Natural Hazards, 2022)

New species and new record of Alternaria from onion leaf blight in Myanmar - Aye Aye Htun; Hai Feng Liu; Lin He; Zhen Zhou Xia; Sein Lai Lai Aung; Jian Xin Deng (Mycological Progress, 2022)

LncRNA NRON negatively regulates cisplatin-induced cell apoptosis via downregulating miR-31 in esophageal squamous cell carcinomas - Bo Liu; Xu Li; Jinbao Xie; Zhi Feng; Nanlong Lin; Minjie Yu (In Vitro Cellular & Developmental Biology - Animal, 2022)

Study on In-seam Wave Response Characteristics of Reflection in Fault Bearing Coal Seam of Shuangliu Coal Mine - Lei Zhang; Lin Xu; Zhulin Wei; Congcong Feng (Geotechnical and Geological Engineering, 2022)

Comparative Analysis of Rock Damage Models Based on Different Distribution Functions - Hang Lin; Jingjing Feng; Rihong Cao; Shijie Xie (Geotechnical and Geological Engineering, 2022)

Regulatory role of miR-129 and miR-384-5p on apoptosis induced by oxygen and glucose deprivation in PC12 cell - Hui-Lin Guan; Yue Guan; Wen-Yuan Li; Jia-Wei Liu; Yu-Jia Zheng; Yan-Zhong Guan; Hong-Feng Liu; Li-Xin Guan; Feng-Guo Zhai (Experimental Brain Research, 2022)

Emission inventory and control policy for non-road construction machinery in Tianjin - Qijun Zhang; Ning Wei; Lei Yang; Xi Feng; Yanjie Zhang; Lin Wu; Hongjun Mao (Environmental Science and Pollution Research, 2022)

The importance of utilizing nitrate (NO3−) over ammonium (NH4+) as nitrogen source during detoxification of exogenous thiocyanate (SCN-) in Oryza sativa - Yu-Juan Lin; Yu-Xi Feng; Xiao-Zhang Yu (Environmental Science and Pollution Research, 2022)

Influence of wing crack propagation on the failure process and strength of fractured specimens - Hengtao Yang; Hang Lin; Yifan Chen; Yixian Wang; Yanlin Zhao; Weixun Yong; Feng Gao (Bulletin of Engineering Geology and the Environment, 2022)

Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells - Xiang-xing Zhu; Jia-sheng Pan; Tao Lin; Ye-cheng Yang; Qiu-yan Huang; Shuai-peng Yang; Zi-xiao Qu; Zi-sheng Lin; Jian-cong Wen; Ai-fen Yan; Juan Feng; Lian Liu; et al. (Biotechnology Letters, 2022)

Dynamic analysis of impulse waves generated by the collapse of granular pillars - Bo-lin Huang; Bin Li; Jia-hao Zheng; Wang-li Feng; Xiao-ting Chen; Chao-lin Luo (Journal of Mountain Science, 2022)

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

Kinetics and Size Effects on Adsorption of Cu(II), Cr(III), and Pb(II) Onto Polyethylene, Polypropylene, and Polyethylene Terephthalate Microplastic Particles - Xiaoxin Han; Shiyu Wang; Xue Yu; Rolf D. Vogt; Jianfeng Feng; Lifang Zhai; Weiqi Ma; Lin Zhu; Xueqiang Lu (Frontiers in Marine Science, 2021)
Due to its small size, large specific surface area and hydrophobicity, microplastics, and the adsorbed contaminants may together cause potential negative effects on ecosystems and human beings. In this study, kinetics and size effects on adsorption of Cu(II), Cr(III), and Pb(II) onto PE, PP and PET microplastic particles were explored. Results indicated that the PE and PET microplastics have the higher adsorption capacity for Cu(II), Cr(III), and Pb(II) than that for PP microplastic. The adsorption capacity was affected by microplastic types and metal species. Among the three metals, Pb(II) had the largest adsorption amount on microplastic particles, especially on PET particles. Moreover, the adsorption capacities of microplastics increase with the decrease of particle size. The metal adsorption capacity of <0.9 mm microplastics is greater than that of 0.9–2 mm and 2–5 mm microplastics. The size effect on metal adsorption was largest for PE microplastic. More attention should be paid in case of the coexistence of heavy metals and tiny PE and PET microplastics in the environment.

210Pb-Derived Bioturbation Rates in Sediments Around Seamounts in the Tropical Northwest Pacific - Feng Lin; Cai Lin; Hui Lin; Xiuwu Sun; Li Lin (Frontiers in Marine Science, 2021)
To evaluate bioturbation coefficients (D B ) and mixing depths (L), 210 Pb and 226 Ra activity was measured in two sediments cores (from water depths of 5,398 m and 4,428 m), which were collected from seamount areas in the Northwest Pacific. Using a steady-state diffusion mode, we estimated D B values of 16.8 and 24.1 cm 2 /a, higher than those in abyssal sediments and those predicted by traditional empirical equations. Corresponding L values varied between 19.3 and 23.1 cm. These high values indicate that seamounts are the area of active bioturbation. A one-dimensional model for the transport of total organic carbon (TOC) from the surface layer of sediments to the deep layer was developed using the distribution pattern of the specific activity of excess 210 Pb ( 210 Pb ex ) and its relationship with TOC. The model showed that the TOC flux transmitted downward by bioturbation was 0.09 mmol/(cm 2 ⋅a) and 0.12 mmol/(cm 2 ⋅a).

Bioactive compounds derived from the marine-derived fungus MCCC3A00951 and their influenza neuraminidase inhibition activity in vitro and in silico - Shun-Zhi Liu; Feng-Ming He; Yan-lin Bin; Chu-Fang Li; Bao-Ying Xie; Xi-Xiang Tang; Ying-Kun Qiu (Natural Product Research, 2021)

Antioxidant CPA-type indole alkaloids produced from the deep-sea derived fungus Aspergillus sp. SCSIO 41024 - Wei-Hao Chen; Kun-Long Li; Xiu-Ping Lin; Sheng-Rong Liao; Bin Yang; Xue-Feng Zhou; Jun-Jian Wang; Yong-Hong Liu; Jun-Feng Wang (Natural Product Research, 2021)

Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice - Xiongjie Fu; Hanhai Zeng; Jikuang Zhao; Guoyang Zhou; Hang Zhou; Jianfeng Zhuang; Chaoran Xu; Jianru Li; Yucong Peng; Yang Cao; Yin Li; Huaijun Chen; et al. (Translational Stroke Research, 2021)

Evolutionary characteristics and phylogeny of cotton chloroplast tRNAs - Ning Wang; Wan-Lin Dong; Xiao-Jing Zhang; Tong Zhou; Xiao-Juan Huang; Bao-Guo Li; Jian-Ni Liu; Xiong-Feng Ma; Zhong-Hu Li (Planta, 2021)

Sigma-1 Receptor Activation Suppresses Microglia M1 Polarization via Regulating Endoplasmic Reticulum–Mitochondria Contact and Mitochondrial Functions in Stress-Induced Hypertension Rats - Kokwin Ooi; Li Hu; Yi Feng; Chenzhi Han; Xiaorong Ren; Xinyi Qian; Haofeng Huang; Sijia Chen; Qi Shi; Hong Lin; Jijiang Wang; Danian Zhu; et al. (Molecular Neurobiology, 2021)

Measuring Heterogeneity in 18F-Fluorodeoxyglucose Positron Emission Tomography Images for Classifying Metastatic and Benign Bone Lesions in Patients with Cervical Cancer - Feng-Yuan Liu; Gigin Lin; Jing-Ren Tseng; Angel Chao; Huei-Jean Huang; Hung-Hsueh Chou; Yu-Chen Chang; Tzu-Chen Yen; Chyong-Huey Lai (Journal of Medical and Biological Engineering, 2021)
Purpose Heterogeneity assessment can be applied for medical imaging analysis. Here, we evaluated first-order and texture analysis (TA) metrics in 18 F-fluorodeoxyglucose ( 18 F-FDG) positron emission tomography (PET) imaging for classification of metastatic and benign bone lesions in patients with cervical cancer. Methods The data of 18 F-FDG PET studies performed on a specific PET/CT system from 2016 to 2018 in patients with cervical cancer were retrieved. The data of bone lesions extracted from studies over 2016–2017 and 2018 were used as training and validation datasets, respectively. Metastatic bone lesions were identified in each dataset, with an equal number of benign bone lesions selected. Cuboid volume of interest (VOI) consisting of 3 × 3 × 5 reconstructed voxels was applied for first-order metrics, and cubic VOI consisting of smaller voxels with trilinear interpolation of standardized uptake value (SUV) was adopted for TA metrics. First-order metrics included the maximum SUV (SUVmax) of lesions and the mean voxel SUV and its standard deviation (SUVsd), skewness, and kurtosis in VOI. In total, 4464 TA metrics based on 62 texture features were evaluated. Logistic regression was used for classification with area under the receiver operating characteristic curve (AUC) as the performance measure. Results From the training and validation datasets, 98 and 42 metastatic bone lesions were identified, respectively. SUVsd demonstrated higher performance than did SUVmax in both the training (AUC .798 vs .732, P = .001) and validation (AUC .786 vs .684, P < .001) datasets. Top-performing TA metrics demonstrated significantly higher performance in the training dataset, but not in the validation dataset. Conclusion A simple first-order measure of heterogeneity, SUVsd, was found to be superior to SUVmax for the classification of metastatic and benign bone lesions. Multiple hypothesis testing can result in false-positive findings in TA with multiple features and parameters; careful validation is required.

Optimizing the Wheat Seeding Rate for Wide-Space Sowing to Improve Yield and Water and Nitrogen Utilization - Zhixin Wang; Shahbaz Khan; Min Sun; Aixia Ren; Wen Lin; Pengcheng Ding; Hafeez Noor; Shaobo Yu; Yu Feng; Qiang Wang; Zhiqiang Gao (International Journal of Plant Production, 2021)

External evaluation of published population pharmacokinetic models of polymyxin B - Ya-qian Li; Kai-feng Chen; Jun-jie Ding; Hong-yi Tan; Nan Yang; Ya-qi Lin; Cui-fang Wu; Yue-liang Xie; Guo-ping Yang; Jing-Jing Liu; Qi Pei (European Journal of Clinical Pharmacology, 2021)

Experimental study on the discharge characteristics of viscous debris flow with grid-type dam - Jinfeng Liu; Dong Yuan; Ming Lu; Yong You; Guangze Zhang; Tao Feng; Dong Wang; Zhiheng Lin (Environmental Fluid Mechanics, 2021)

Experimental and Model Predictive Investigation into the Relationship of pH Alternation with Addition of Lime in Acid Tin Tailing Treatments - Feng Yin; Ying-Jie Li; Qun Zhao; Chen Li; Jie Li; Sen-Lin Tian (Bulletin of Environmental Contamination and Toxicology, 2021)

Selenium-Alleviated Testicular Toxicity by Modulating Inflammation, Heat Shock Response, and Autophagy Under Oxidative Stress in Lead-Treated Chickens - Size Wang; Lulu Hou; Min Wang; Rui Feng; Xu Lin; Shifeng Pan; Qian Zhao; He Huang (Biological Trace Element Research, 2021)

The phosphatidylinositol transfer gene Os08PTS regulating the development and nitrogen metabolism in rice seedling stage - Jingwan Yan; Zhimin Lin; Changquan Hu; Feng Wang (Plant Biotechnology Reports, 2021)

Long-term changes of water acidity in an intact forested watershed in south China - Xiao-dong Liu; Ying-jie Feng; Qi-feng Mo; Guo-wei Chu; Yue-lin Li; Qian-mei Zhang; Wei-qiang Zhang; Xian-hua Gan; Qing Zhou (Journal of Mountain Science, 2021)

Climate Suitability Assessment of Human Settlements for Regions along the Belt and Road - Yumei Lin; Peng Li; Zhiming Feng; Yanzhao Yang; Zhen You; Fuxin Zhu (Chinese Geographical Science, 2021)

Retraction Note: Cost control model of marine crude oil pollutant degradation based on game analysis - Rongli Dun; Lin Xue; Jiaxiang Feng (Arabian Journal of Geosciences, 2021)

Phenolic glycosides and flavonoids with antioxidant and anticancer activities from Desmodium caudatum - Qian-Nan Xu; Dan Zhu; Guang-Hui Wang; Ting Lin; Cui-Ling Sun; Rong Ding; Wen-Jing Tian; Hai-Feng Chen (Natural Product Research, 2021)

Chemical constituents from the barks of Melia azedarach and their PTP1B inhibitory activity - Sheng-Nan Zhang; Lin Huang; Rui-Jing Ma; Mei-Feng Yang; Ben-Fu Wei; Hong-Zhi Song; Heng-Shan Wang; Qin-Gang Tan (Natural Product Research, 2021)

Estimation of forest aboveground biomass by using mixed-effects model - Haoning Feng; Qi Chen; Yueming Hu; Zhiguo Du; Guantu Lin; Changwei Wang; Youju Huang (International Journal of Remote Sensing, 2021)

The Beneficial Role of Exercise on Treating Alzheimer’s Disease by Inhibiting β-Amyloid Peptide - Zi-Xuan Tan; Fang Dong; Lin-Yu Wu; Ya-Shuo Feng; Feng Zhang (Molecular Neurobiology, 2021)

Dopaminergic Projection from Ventral Tegmental Area to Substantia Nigra Pars Reticulata Mediates Chronic Social Defeat Stress–Induced Hypolocomotion - Feng He; Pei Zhang; Qian Zhang; Guangjian Qi; Hongwei Cai; Tongxia Li; Ming Li; Jiazhen Lu; Jiaen Lin; Jie Ming; Bo Tian (Molecular Neurobiology, 2021)

Development and validation of gene-specific KASP markers for YrAS2388R conferring stripe rust resistance in wheat - Yanling Hu; Xuhui Huang; Fang Wang; Yu He; Lihua Feng; Bo Jiang; Ming Hao; Shunzong Ning; Zhongwei Yuan; Jiajie Wu; Lianquan Zhang; Bihua Wu; et al. (Euphytica, 2021)

Effects of Low‐dose Mercury Exposure in Newborns on mRNA Expression Profiles - Haohao Liu; Chanchan Zhang; Fuli Wen; Lin Feng; Huiqun Wang; Wenjuan Wang; Ping Li (Bulletin of Environmental Contamination and Toxicology, 2021)

Spatiotemporal change of vegetation coverage recovery and its driving factors in the Wenchuan earthquake-hit areas - Xiao-fei Sun; Lin-guo Yuan; Ying-zhi Zhou; Huai-yong Shao; Xian-feng Li; Ping Zhong (Journal of Mountain Science, 2021)

Decadal variation of thermocline-sea surface temperature feedback in the tropical Indian Ocean and the underlying mechanisms - Meiqi Zhang; Shuangwen Sun; Lin Liu; Yongcan Zu; Lin Feng (Acta Oceanologica Sinica, 2021)

A new abietane diterpene and anti-complementary constituents from Juniperus tibetica - Dong-Lin Zeng; Chang-Yue Wang; Hui-Qin Gao; Dao-Feng Chen; Yan Lu (Natural Product Research, 2021)

Age-dependent microRNAs in regulation of vascular cambium activity in Chinese fir (Cunninghamia lanceolata) - Guijun Liu; Xian Xue; Jinling Feng; Dechang Cao; Jinxing Lin; Huimin Xu (Trees, 2021)

Functional analysis of indole 3-hexanoic acid as a novel auxin from Arabidopsis thaliana - Ping Song; Hui Xu; Jixiu Zhang; Huatao Chen; Li Li; Yana Qu; Feng Lin; Qun Zhang (Planta, 2021)

The Decision Strategies of Adolescents with Different Emotional Stabilities in Unfair Situations - Yajing Si; Lin Jiang; Chanlin Yi; Qi Zhang; Cunbo Li; Jing Yu; Peiyang Li; Qiang Liu; Feng Wan; Fali Li; Dezhong Yao; Peng Xu (Neuroscience Bulletin, 2021)

Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult Mice - Lin Chen; Shu-Yu Ren; Rui-Xue Li; Kun Liu; Jing-Fei Chen; Yu-Jian Yang; Yong-Bin Deng; Han-Zhi Wang; Lan Xiao; Feng Mei; Fei Wang (Neuroscience Bulletin, 2021)
Exposure to chronic hypoxia is considered to be a risk factor for deficits in brain function in adults, but the underlying mechanisms remain largely unknown. Since active myelinogenesis persists in the adult central nervous system, here we aimed to investigate the impact of chronic hypoxia on myelination and the related functional consequences in adult mice. Using a transgenic approach to label newly-generated myelin sheaths ( NG2-CreER TM ; Tau-mGFP ), we found that myelinogenesis was highly active in most brain regions, such as the motor cortex and corpus callosum. After exposure to hypoxia (10% oxygen) 12 h per day for 4 weeks, myelinogenesis was largely inhibited in the 4-month old brain and the mice displayed motor coordination deficits revealed by the beam-walking test. To determine the relationship between the inhibited myelination and functional impairment, we induced oligodendroglia-specific deletion of the transcription factor Olig2 by tamoxifen ( NG2-CreER TM ; Tau-mGFP; Olig2 fl/fl ) in adult mice to mimic the decreased myelinogenesis caused by hypoxia. The deletion of Olig2 inhibited myelinogenesis and consequently impaired motor coordination, suggesting that myelinogenesis is required for motor function in adult mice. To understand whether enhancing myelination could protect brain functions against hypoxia, we treated hypoxic mice with the myelination-enhancing drug-clemastine, which resulted in enhanced myelogenesis and improved motor coordination. Taken together, our data indicate that chronic hypoxia inhibits myelinogenesis and causes functional deficits in the brain and that enhancing myelinogenesis protects brain functions against hypoxia-related deficits.

Circ_0020093 ameliorates IL-1β-induced apoptosis and extracellular matrix degradation of human chondrocytes by upregulating SPRY1 via targeting miR-23b - Mingli Feng; Lin Jing; Jingbo Cheng; Shuai An; Jiang Huang; Qi Yan (Molecular and Cellular Biochemistry, 2021)
Osteoarthritis (OA) is a chronic disease characterized by articular cartilage degeneration and uncontrolled chondrocyte apoptosis. At present, accumulating evidence introduces that circular RNA (circRNA) is involved in the development of OA. The aim of our study was to explore the role and the functional mechanism of circ_0020093 in OA cell model. Human chondrocytes were treated with interleukin-1 beta (IL-1β) to construct OA model. The expression of circ_0020093, miR-23b, and Sprouty 1 (SPRY1) mRNA was measured by quantitative real-time polymerase chain reaction (qRT-PCR). Cell apoptosis was assessed by flow cytometry assay. The expression of extracellular matrix (ECM)-associated markers and SPRY1 protein level was detected by qRT-PCR and Western blot. Bioinformatics analysis-predicted relationship between miR-23b and circ_0020093 or SPRY1 was further verified by dual-luciferase reporter assay and RNA pull-down assay. In this study, we found that the expression of circ_0020093 and SPRY1 was declined, while miR-23b expression was elevated in IL-1β-treated chondrocytes. IL-1β induced chondrocyte apoptosis and ECM degradation, while these negative effects were alleviated by circ_0020093 overexpression or miR-23b inhibition. MiR-23b was a target of circ_0020093, and SPRY1 was a downstream target of miR-23b. Rescue experiments showed that miR-23b enrichment reversed the role of circ_0020093 overexpression, and SPRY1 knockdown also reversed the effects of miR-23b inhibition. Importantly, circ_0020093 positively regulated SPRY1 expression by targeting miR-23b. In conclusion, circ_0020093 ameliorates IL-1β-induced apoptosis and ECM degradation of human chondrocytes by regulating the miR-23b/SPRY1 axis.

Anti-miR33 therapy improved hepatopancreatic lipid and immune metabolism disorders in grass carp, Ctenopharyngodon idella - Rong-Hua Lu; Meng-Jun Lin; Feng Yang; Shen-zong Jia; Yu-Ru Zhang; Chao-Bin Qin; Xiao-Lin Meng; Guo-Xing Nie (Fish Physiology and Biochemistry, 2021)

Research on a new cationic polyacrylamide (CPAM) with a cationic microblock structure and its enhanced effect on sludge condition and dewatering - Yuning Chen; Xuhao Li; Wang Zizeng; Li Feng; Jiehong Xie; Zeluan Lin; Zhihong Xu; Bingzhi Liu; Xiang Li; Huaili Zheng (Environmental Science and Pollution Research, 2021)

Rockburst response in hard rock owing to excavation unloading of twin tunnels at great depth - Fan Feng; Xibing Li; Lin Luo; Xingdong Zhao; Shaojie Chen; Ning Jiang; Wanpeng Huang; Yajun Wang (Bulletin of Engineering Geology and the Environment, 2021)

Shared and specific patterns of structural and functional thalamo-frontal disturbances in manic and euthymic pediatric bipolar disorder - Yi-Bing Guo; Wei-Jia Gao; Zhi-Liang Long; Wei-Fang Cao; Dong Cui; Yong-Xin Guo; Qing Jiao; Jian-Feng Qiu; Lin-Yan Su; Guang-Ming Lu (Brain Imaging and Behavior, 2021)
Bipolar disorder (BD) is clinically defined by alternating depressive and manic episodes with a separated period of euthymia. Thalamo-frontal loop plays vital role in psychotic symptoms, altered motor control and executive difficulties in BD. It remains unclear that structural and functional alterations of thalamo-frontal loop among the different mood states in BD, especially in pediatric BD(PBD). Twenty manic PBD (mPBD), 20 euthymic PBD (ePBD) and 19 healthy controls (HCs) were included in the study. By analyzing the T1 images and fMRI signals, thalamus volume and frontal grey matter cortical thickness were tested, and functional connectivity (FC) between bilateral thalamus and frontal cortex was calculated. Relationship between clinical indices and thalamo-frontal FC was also evaluated in mPBD and ePBD adolescents. Compared to HCs, the cortical thickness of left middle frontal gyrus (MFG), bilateral superior frontal gyrus (SFG) was significantly decreased in both mPBD and ePBD patients, and volume of left thalamus and cortical thickness of right MFG significantly decreased in mPBD patients. Compared to that of the HCs and ePBD subjects, thalamo-frontal hyperconnectivity with MFG was found in mPBD, and compared with that of HCs, thalamo-frontal hypoconnectivity with precentral gyrus/SFG was found in ePBD. In ePBD patients, episode times positively correlated with FC values between thalamus and precentral gyrus. The findings of the present study demonstrate detailed knowledge regarding shared and specific structural and functional disruption in thalamo-frontal loop in mPBD and ePBD subjects. Thalamo-frontal abnormalities reported in adult BD subjects were also observed in adolescent BD patients, and thalamo-frontal dysfunction may be a crucial treatment target in BD.

Degraded polysaccharides from Porphyra haitanensis: purification, physico-chemical properties, antioxidant and immunomodulatory activities - Yun-Feng Huo; Yin-Ting Li; Wei Xia; Chong Wang; Yuan-Yuan Xie; Yan-Bo Wang; Tao Zhou; Ling-Lin Fu (Glycoconjugate Journal, 2021)

Sandaracinobacteroides hominis gen. nov., sp. nov., isolated from human skin - Ping-Hua Qu; Hai-Min Luo; Jun-Hui Feng; Song Li; Cha Chen; Lei Dong; Yu-Zhen Ming; Wen-Jun Li; Ying Lin (Archives of Microbiology, 2021)

Effects of Fatigue on Inter-joint Coordination in Ballet Dancers During a Ballet Jumping Movement (petit échappé sauté) - Chai-Wei Lin; Jeng-Feng Yang; Yi-An Chen; Cheng-Feng Lin (Journal of Medical and Biological Engineering, 2021)

Rice yellow stunt virus activates polyamine biosynthesis to promote viral propagation in insect vectors by disrupting ornithine decarboxylase antienzyme function - Xiao-Feng Zhang; Tianbao Zeng; Yunjie Xie; Yuemin Zheng; Huanqin Wang; Hanbin Lin; Zongwen Wang; Taiyun Wei (Science China Life Sciences, 2021)

Identification of a major QTL related to resistance to soybean mosaic virus in diverse soybean genetic populations - Jiahao Chu; Wenlong Li; Dongri Piao; Feng Lin; Xiaobo Huo; Hua Zhang; Hui Du; Youbin Kong; Yuan Jin; Xihuan Li; Caiying Zhang (Euphytica, 2021)

Rapid transition from MORB-type to SSZ-type oceanic crust generation following subduction initiation: insights from the mafic dikes and metamorphic soles in the Pozantı-Karsantı ophiolite, SE Turkey - Guang-Yao Xin; Yang Chu; Ben-Xun Su; Wei Lin; Ibrahim Uysal; Zhen-Tian Feng (Contributions to Mineralogy and Petrology, 2021)

Application of the modified cytosine base-editing in the cultured cells of bama minipig - Jia-sheng Pan; Zi-sheng Lin; Jian-cong Wen; Jian-feng Guo; Xia-hui Wu; Ying-ying Liu; Wen-jun Lai; Qi-ying Liang; Yong-shi Xie; Yi-rou Chen; Yi-hong Chen; Ai-fen Yan; et al. (Biotechnology Letters, 2021)

Novel Dicistroviruses in an Unexpected Wide Range of Invertebrates - Ruo-Lin Cheng; Xiao-Feng Li; Chuan-Xi Zhang (Food and Environmental Virology, 2021)

The Individual and Synergistic Indexes for Assessments of Heavy Metal Contamination in Global Rivers and Risk: a Review - Hong-Giang Hoang; Chitsan Lin; Chow-Feng Chiang; Xuan-Thanh Bui; Wisanukorn Lukkhasorn; Thi-Phuong-Thuy Bui; Huu-Tuan Tran; Thi-Dieu-Hien Vo; Van-Giang Le; Long D. Nghiem (Current Pollution Reports, 2021)

3D Step-by-step inversion strategy for audio magnetotellurics data based on unstructured mesh - San Cheng; Zhi-Yong Zhang; Feng Zhou; Man Li; Hui Chen; Fu-Sheng Shi; Lin-Pin Huang; Yong Li (Applied Geophysics, 2021)

Wogonin Accelerates Hematoma Clearance and Improves Neurological Outcome via the PPAR-γ Pathway After Intracerebral Hemorrhage - Jianfeng Zhuang; Yucong Peng; Chi Gu; Huihui Chen; Zheng Lin; Hang Zhou; Xiao Wu; Jianru Li; Xiaobo Yu; Yang Cao; Hanhai Zeng; Xiongjie Fu; et al. (Translational Stroke Research, 2021)

Prediction of Metabolic Disorders Using NMR-Based Metabolomics: The Shanghai Changfeng Study - Qi Wu; Qing-xia Huang; Hai-luan Zeng; Shuai Ma; Huan-dong Lin; Ming-feng Xia; Hui-ru Tang; Xin Gao (Phenomics, 2021)

Dicer Deletion in Astrocytes Inhibits Oligodendroglial Differentiation and Myelination - Kun Liu; Bin Yu; Jing-Fei Chen; Rui-Xue Li; Lin Chen; Shu-Yu Ren; Fei Wang; Feng Mei; Lan Xiao (Neuroscience Bulletin, 2021)
Increasing evidence has shown that astrocytes are implicated in regulating oligodendrocyte myelination, but the underlying mechanisms remain largely unknown. To understand whether microRNAs in astrocytes function in regulating oligodendroglial differentiation and myelination in the developing and adult CNS, we generated inducible astrocyte-specific Dicer conditional knockout mice (hGFAP-CreERT; Dicer fl/fl). By using a reporter mouse line (mT/mG), we confirmed that hGFAP-CreERT drives an efficient and astrocyte-specific recombination in the developing CNS, upon tamoxifen treatment from postnatal day 3 (P3) to P7. The Dicer deletion in astrocytes resulted in inhibited oligodendroglial differentiation and myelination in the developing CNS of Dicer cKO mice at P10 and P14, and did not alter the densities of neurons or axons, indicating that Dicer in astrocytes is required for oligodendrocyte myelination. Consequently, the Dicer deletion in astrocytes at P3 resulted in impaired spatial memory and motor coordination at the age of 9 weeks. To understand whether Dicer in astrocytes is also required for remyelination, we induced Dicer deletion in 3-month-old mice and then injected lysolecithin into the corpus callosum to induce demyelination. The Dicer deletion in astrocytes blocked remyelination in the corpus callosum 14 days after induced demyelination. Together, our results indicate that Dicer in astrocytes is required for oligodendroglia myelination in both the developing and adult CNS.

Refractory organic compounds in coal chemical wastewater treatment by catalytic ozonation using Mn-Cu-Ce/Al2O3 - Kang-He Zhao; Yu-Long Ma; Feng Lin; Shao-Ying Ge; Li Zhu (Environmental Science and Pollution Research, 2021)

The glutathione S-transferase (PxGST2L) may contribute to the detoxification metabolism of chlorantraniliprole in Plutella xylostella(L.) - Fei Yin; Qingsheng Lin; Xiaoxiang Wang; Zhenyu Li; Xia Feng; Muhammad Zeeshan Shabbir (Ecotoxicology, 2021)
The diamondback moth ( Plutella xylostella L.), is an economic pest of cruciferous plants worldwide, which causes great economic loss to cruciferous plants production. However, the pest has developed resistance to insecticides. One of such insecticides is chlorantraniliprole. The study of the mechanisms underlying resistance is key for the effective management of resistance. In this study, a comparative proteomics approach was used to isolate and identify various proteins that differed between chlorantraniliprole-susceptible and -resistant strains of P. xylostella . Eleven proteins were significantly different and were successfully identified by MALDI-TOF-MS. Metabolism-related proteins accounted for the highest proportion among the eleven different proteins. The function of the PxGST2L protein was validated by RNAi. Knockdown of PxGST2L reduced the GST activity and increased the toxicity of chlorantraniliprole to the diamondback moth. The resistance ratio of diamondback moth to chlorantraniliprole was reduced from 1029 to 505. The results indicated that PxGST2L is partly responsible for chlorantraniliprole insecticide resistance in DBM. Our finding contributes to the understanding of the mechanism underlying resistance to chlorantraniliprole in the DBM, to develop effective resistance management tactics.

Bearing mechanism of a tunnel-type anchorage in a railway suspension bridge - Nan Jiang; Duo Wang; Jun Feng; Sheng-liang Zhang; Lin Huang (Journal of Mountain Science, 2021)

Spatiotemporal analysis of temperature data trends in Peninsular Malaysia - Hun Vui Woo; Jing Lin Ng; Yuk Feng Huang; Celine Chong; Jin Chai Lee (Arabian Journal of Geosciences, 2021)

RSF1 requires CEBP/β and hSNF2H to promote IL-1β-mediated angiogenesis: the clinical and therapeutic relevance of RSF1 overexpression and amplification in myxofibrosarcomas - Chien-Feng Li; Ti-Chen Chan; Cheng-I. Wang; Fu-Min Fang; Po-Chun Lin; Shih-Chen Yu; Hsuan-Ying Huang (Angiogenesis, 2021)

Geographic and subsequent biotic isolations led to a diversity anomaly of section Heterotropa (genus Asarum : Aristolochiaceae) in insular versus continental regions of the Sino‐Japanese Floristic Region - Daiki Takahashi; Shota Sakaguchi; Yu Feng; Yuji Isagi; Ying‐Xiong Qiu; Pan Li; Rui‐Sen Lu; Chang‐Tse Lu; Shih‐Wen Chung; Yang‐Shan Lin; Yun‐Chao Chen; Atsushi J. Nagano; et al. (Journal of Biogeography, 2021)
Aim The Sino‐Japanese Floristic Region has extremely high species diversity with respect to temperate plants; however, the reasons for this diversity are poorly understood because most studies have only considered geographic isolation caused by climatic oscillations. In some plant groups, high floral trait diversity and uneven species diversity between insular systems and the continental area suggest other factors may have important roles too. The primary purpose of this study is to reveal how abiotic and biotic factors have shaped the species diversity anomaly of Heterotropa between the insular systems and the continental area. Location The Sino‐Japanese Floristic Region. Taxon Section Heterotropa (genus Asarum ; Aristolochiaceae). Methods Using ddRAD‐seq and chloroplast genome data, we built a time‐calibrated phylogenetic tree including 79 species. We estimated the patterns of floral traits (flowering time and floral size) evolution using macroevolutionary modelling, and tested the correlation of speciation rate with the trait evolution rates. Finally, we estimated the isolation factors of all taxa pairs and sister‐taxa pairs based on distribution range and floral traits. Results Phylogenetic analysis indicated that Heterotropa was diverged into two clades (continental clade and insular clade) in the Miocene, and the major subclades corresponded to geographic entities. Most rate shifts accelerating floral trait's evolution occurred during the Pleistocene period. Evolution rate of floral traits showed positive correlation with the speciation rate. Large proportion of taxa in the insular clade are distributed allopatrically. Several sister pairs showed floral trait divergence with geographic overlap. Main Conclusions The diversification of Heterotropa appears to have been triggered by geographic and climatic events, and subsequent repeated floral trait evolution with and without geographic isolation. Furthermore, the high species diversity in the insular systems would have been formed by the repeated range fragmentations and contractions. Our study demonstrates the importance of multidimensional studies to understand the diversification process of temperate plants in the Sino‐Japanese Floristic Region.

A new ent -kaurane diterpene from Isodon henryi - Xue Jiang; Ling-Xia Zhang; Qing-Mei Feng; Hong Wu; Ya-Lin Liu; De-Qin Wang; Li-Ping Dai; Zhi-Min Wang (Natural Product Research, 2021)

The Characteristic of Critical Genes in Neuroendocrine System and Their Regulation on Food Habit Transition and Metamorphosis of Veined Rapa Whelk Rapana venosa (Valenciennes, 1846) - Mei-Jie Yang; Jie Feng; Hao Song; Zheng-Lin Yu; Pu Shi; Jian Liang; Zhi Hu; Cong Zhou; Xiao-Lin Wang; Tao Zhang (Frontiers in Marine Science, 2021)
Metamorphosis is a critical developmental event in mollusks, and neuroendocrine system plays an essential role in this process. Rapana venosa is an economically important shellfish in China, but the artificial technology of R. venosa aquaculture is limited by metamorphosis. As a carnivorous gastropod, food habit transition makes the mechanism of R. venosa metamorphosis more complex. To investigate the changes in the neuroendocrine system and to reveal its role in regulating the food habit transition and metamorphosis of R. venosa , we cloned the cDNA sequences encoding 5-hydroxytryptamine receptor ( Rv-5HTR ), nitric oxide synthetase ( Rv-NOS ) and cholecystokinin receptor ( Rv-CCKR ), and investigated their expression by quantitative real-time PCR analysis, and explore the spatio-temporal changes of 5-HT protein expression using Immunohistochemical (IHC) analysis. The expression of the three geens was significantly increased in the early intramembrane veliger stage, which indicates that the three genes are related to the development of digestive system. Additionally, expression of the three genes was decreased after metamorphosis, while Rv-NOS and Rv-CCKR were increasingly expressed in competent larvae, which may help the larvae find suitable environments and promote digestive system development for metamorphosis, and the result of 5-HT IHC analysis also reflects the development of neuroendocrine system. Furthermore, results show that CCK can effect the expression of digestive enzyme, NOS and 5-HT receptor. Finally, based on the present results, we hypothesized that CCK and CCK receptor may be critical regulatory factors of food habit transition and metamorphosis. These results might provide information on the development of neuroendocrine system of R. venosa , and new insight into the regulation of the food habit transition and metamorphosis of gastropods.

Molecular mapping of quantitative disease resistance loci for soybean partial resistance to Phytophthora sansomeana - Feng Lin; Wenlong Li; Austin G. McCoy; Xuan Gao; Paul J. Collins; Na Zhang; Zixiang Wen; Sizhe Cao; Shabir H. Wani; Cuihua Gu; Martin I. Chilvers; Dechun Wang (Theoretical and Applied Genetics, 2021)

Quantification of SARS-CoV-2 antigen levels in the blood of patients with COVID-19 - Bin Su; Jiming Yin; Xingguang Lin; Tiantian Zhang; Xiao Yao; Ying Xu; Yao Lu; Wenzhi Wang; Kun Liu; Jie Zhang; Liangzhi Xie; Ronghua Jin; et al. (Science China Life Sciences, 2021)

Comparative analysis of sRNAs, degradome and transcriptomics in sweet sorghum reveals the regulatory roles of miRNAs in Cd accumulation and tolerance - Weitao Jia; Kangqi Lin; Tengxue Lou; Juanjuan Feng; Sulian Lv; Ping Jiang; Ze Yi; Xuan Zhang; Duoliya Wang; Zijing Guo; Yetao Tang; Rongliang Qiu; et al. (Planta, 2021)

MicroRNA-9 rescues hyperglycemia-induced endothelial cell dysfunction and promotes arteriogenesis through downregulating Notch1 signaling - Huang Chen; Zhihai Feng; Lieyou Li; Lin Fan (Molecular and Cellular Biochemistry, 2021)

Failure mechanism of a slow-moving landslide on September 27, 2020, in Chang Nong Village, Guangxi, China - Jiaming Zhang; Zhi Zhou; Feng Lin; Qinggang Yang; Yi Luo (Landslides, 2021)

A luminescent Zn(II)-Containing Complex: Selective Sensing of Cr(VI) Anion and Application Values on Tuberculosis Care Through Increasing the Antibacterial Response of Macrophages - Jin-Chao Mao; Jin-Jing Hong; Ming-Zheng Lin; Feng Han; Dong Li (Journal of Fluorescence, 2021)

Phytoavailability, translocation and soil thresholds derivation of cadmium for food safety through soil-wheat (Triticum aestivum L.) system - Min Lu; Xuerui Cao; Qiang Lin; Bilal Hussain; Ying Feng; Zhenli He; Kyong Ju Kang; Xiaoe Yang (Environmental Science and Pollution Research, 2021)

Acute effects of particulate matter with different sizes on respiratory mortality in Shenzhen, China - Feng Zhu; Lan Chen; Zhengmin Qian; Yuxue Liao; Zhen Zhang; Stephen Edward McMillin; Xiaojie Wang; Hualiang Lin (Environmental Science and Pollution Research, 2021)

A massive ancient river-damming landslide triggered by buckling failure in the upper Jinsha River, SE Tibetan Plateau - Yanyan Li; Xuyang Feng; Aijun Yao; Shan Lin; Rui Wang; Mingzhu Guo (Bulletin of Engineering Geology and the Environment, 2021)

Glaciibacter flavus sp. nov., isolated from a lichen sample - De-Feng An; Long-Qian Jiang; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Ming-Guo Jiang; Lei Lang; Li-Song Wang; Johannes F. Imhoff; Cheng-Lin Jiang; Yi Jiang (Archives of Microbiology, 2021)

The mechanism and application of high-pressure water jet technology to prevent compound dynamic disaster - Zeng-qiang Yang; Chang Liu; Feng-shuo Li; Lin-ming Dou; Gang-wei Li; Da-wei Wang (Arabian Journal of Geosciences, 2021)

Cysteiniphilum marinum sp. nov., isolated from coastal seawater - Hai-Min Luo; Jun-Hui Feng; Liang-Hui Li; Meng-Meng Li; Ru-Qin Liu; Fu Chen; Ying Lin; Wen-Jun Li; Ping-Hua Qu; Min Xiao (Antonie van Leeuwenhoek, 2021)

Actirhodobacter atriluteus gen. nov., sp. nov., isolated from the surface water of the Yellow Sea - Hua-Peng Xue; Dao-Feng Zhang; Lin Xu; Xiang-Ning Wang; Ai-Hua Zhang; Jian-Ke Huang; Chuang Liu (Antonie van Leeuwenhoek, 2021)

In-Situ Seawater Gamma Spectrometry with LaBr3 Detector at a Nuclear Power Plant Outlet - Daowei Dou; Zhi Zeng; Wen Yu; Ming Zeng; Wu Men; Feng Lin; Hao Ma; Jianping Cheng; Junli Li (Journal of Marine Science and Engineering, 2021)
In a nuclear emergency, the application of in situ spectrometers for monitoring environmental radioactivity is significantly important, as information on the type and activity of radionuclides released from the accident can be obtained quickly. However, in emergency environmental radiological monitoring, a balance between energy resolution and detecting efficiency must be considered in selecting an appropriate detector. In this study, in situ gamma spectrometry was conducted with the LaBr3 detector to determine the radioactivity of seawater at the discharging outlet of a coastal nuclear power plant in southeast China. The results show that the LaBr3 scintillator has excellent energy resolution and detection efficiency, making it a promising detector for emergency monitoring.

Detection of Vestibular Schwannoma on Triple-parametric Magnetic Resonance Images Using Convolutional Neural Networks - Tzu-Hsuan Huang; Wei-Kai Lee; Chih-Chun Wu; Cheng-Chia Lee; Chia-Feng Lu; Huai-Che Yang; Chun-Yi Lin; Wen-Yuh Chung; Po-Shan Wang; Yen-Ling Chen; Hsiu-Mei Wu; Wan-You Guo; et al. (Journal of Medical and Biological Engineering, 2021)
Purpose The first step in typical treatment of vestibular schwannoma (VS) is to localize the tumor region, which is time-consuming and subjective because it relies on repeatedly reviewing different parametric magnetic resonance (MR) images. A reliable, automatic VS detection method can streamline the process. Methods A convolutional neural network architecture, namely YOLO-v2 with a residual network as a backbone, was used to detect VS tumors from MR images. To heighten performance, T1-weighted–contrast-enhanced, T2-weighted, and T1-weighted images were combined into triple-channel images for feature learning. The triple-channel images were cropped into three sizes to serve as input images of YOLO-v2. The VS detection effectiveness levels were evaluated for two backbone residual networks that downsampled the inputs by 16 and 32. Results The results demonstrated the VS detection capability of YOLO-v2 with a residual network as a backbone model. The average precision was 0.7953 for a model with 416 × 416-pixel input images and 16 instances of downsampling, when both the thresholds of confidence score and intersection-over-union were set to 0.5. In addition, under an appropriate threshold of confidence score, a high average precision, namely 0.8171, was attained by using a model with 448 × 448-pixel input images and 16 instances of downsampling. Conclusion We demonstrated successful VS tumor detection by using a YOLO-v2 with a residual network as a backbone model on resized triple-parametric MR images. The results indicated the influence of image size, downsampling strategy, and confidence score threshold on VS tumor detection.

Influence of Combined Motion of Pitch and Surge with Phase Difference on Aerodynamic Performance of Floating Offshore Wind Turbine - Xiangheng Feng; Yonggang Lin; Guohao Zhang; Danyang Li; Hongwei Liu; Bin Wang (Journal of Marine Science and Engineering, 2021)
Platform motions induced by waves pose a challenge to accurately predict the aerodynamic performance of floating offshore wind turbines (FOWTs). In view of this, the power performance and wake structure of FOWTs under platform pitch, surge, and their combined motions were investigated in this paper, using the computational fluid dynamics software, STAR-CCM+, with overset meshing and rigid body motion techniques. First, the simulation cases in single and same-phase combined motions with different amplitudes and frequencies were performed. Afterward, the approach of calculating the phase difference between pitch and surge motions was proposed to investigate the influence of the combined motion with phase difference on the aerodynamic performance. Results show that the increment of amplitude and frequency augments the mean power output and aggravates the power fluctuation in single and same-phase combined motions. The intensity of power variation under combined motion with a phase difference is weakened at 0.1 Hz compared to the single motion, while enhanced at 0.2 Hz, showing a different influence law on the aerodynamic performance. In addition, this paper established the power fluctuation table based on real sea states of Shidao in China, providing a certain reference for the controller design in this sea area.

Flavonoids from Artemisia rupestris and their synergistic antibacterial effects on drug-resistant Staphylococcus aureus - Jiang-Er Lan; Xiao-Jin Li; Xiao-Feng Zhu; Zhong-Lin Sun; Jian-Ming He; Mire Zloh; Simon Gibbons; Qing Mu (Natural Product Research, 2021)

Neuroprotective Effects of 2-Substituted 1, 3-Selenazole Amide Derivatives on Amyloid-Beta-Induced Toxicity in a Transgenic Caenorhabditis Elegans Model of Alzheimer’s Disease - Huiying Wang; Yuandong Yue; Haifeng Zhao; Hao Wu; Kai Jiang; Shuang Li; Meihua Zhao; Feng Lin (Neurotoxicity Research, 2021)

N6-methyladenine DNA Demethylase ALKBH1 Regulates Mammalian Axon Regeneration - Qiao Li; Cheng Qian; Harry Feng; Tyger Lin; Qingsan Zhu; Ying Huang; Feng-Quan Zhou (Neuroscience Bulletin, 2021)

Serum macrophage migration inhibitory factor as a potential biomarker to evaluate therapeutic response in patients with allergic asthma: an exploratory study - Huiyuan Zhu; Shaochun Yan; Jingshuo Wu; Zhong Zhang; Xiaolin Li; Zheng Liu; Xing Ma; Lina Zhou; Lin Zhang; Mingming Feng; Yiwei Geng; Aixin Zhang; et al. (Journal of Zhejiang University-SCIENCE B, 2021)

Upregulation of CPNE3 suppresses invasion, migration and proliferation of glioblastoma cells through FAK pathway inactivation - Dijian Shi; Bo Lin; Jun Lai; Kaipeng Li; Yimo Feng (Journal of Molecular Histology, 2021)

Assessment of the transfer of heavy metals in seawater, sediment, biota samples and determination the baseline tissue concentrations of metals in marine organisms - Yongfei Gao; Yanlong Qiao; Yushan Xu; Lin Zhu; Jianfeng Feng (Environmental Science and Pollution Research, 2021)

Patients with first-episode untreated schizophrenia who experience concomitant visual disturbances and auditory hallucinations exhibit co-impairment of the brain and retinas—a pilot study - Chuanjun Zhuo; Bo Xiao; Feng Ji; Xiaodong Lin; Deguo Jiang; Hongjun Tian; Yong Xu; Wenqiang Wang; Ce Chen (Brain Imaging and Behavior, 2021)

A dye combination for the staining of pollen coat and pollen wall - Xin-Lei Jia; Jing-Shi Xue; Fang Zhang; Chi Yao; Shi-Yi Shen; Chang-Xu Sui; Yu-Jia Peng; Qin-Lin Xu; Yi-Feng Feng; Wen-Jing Hu; Ping Xu; Zhong-Nan Yang (Plant Reproduction, 2021)

Numerical Analysis of the Water-blocking Performance of a Floor with a Composite Structure under Fluid–solid Coupling - Ang Li; Qian Mu; Li Ma; Chaoyang Liu; Shengquan Wang; Feng Wang; Lin Mou (Mine Water and the Environment, 2021)

Quantitative characterization of horizontal well production performance with multiple indicators: a case study on the Weiyuan shale gas field in the Sichuan Basin, China - Rongze Yu; Wei Guo; Lin Ding; Meizhu Wang; Feng Cheng; Xiaowei Zhang; Shangwen Zhou; Leifu Zhang (Frontiers of Earth Science, 2021)

Detection of Human Sapoviruses in Sewage in China by Next Generation Sequencing - Ke Song; Xiaojuan Lin; Yao Liu; Feng Ji; Li Zhang; Peng Chen; Chenxu Zhao; Yanyan Song; Zexin Tao; Aiqiang Xu (Food and Environmental Virology, 2021)

Kelp aquaculture in China: a retrospective and future prospects - Zi‐Min Hu; Ti‐Feng Shan; Jie Zhang; Quan‐Sheng Zhang; Alan T. Critchley; Han‐Gil Choi; Norishige Yotsukura; Fu‐Li Liu; De‐Lin Duan (Reviews in Aquaculture, 2021)
Globally, China has the largest scale of kelp cultivation and production operations. However, its kelp aquaculture industry is suffering from declining germplasm diversity, degradation of agronomic traits, the presence of polluted environments, changing ocean conditions and increasing anthropological interference. This review covers two of the most commercially important kelp species in China, viz. Saccharina japonica and Undaria pinnatifida . It summarizes the history of their cultivation, production, economic and ecological benefits, their breeding programmes (e.g. inter‐ and intra‐specific hybridization and marker‐assisted selection) and efforts towards population genetic diversity and conservation. The article focuses on three significant challenges, for example genetic cross‐contamination between the wild and farmed kelp populations, ocean warming and ocean acidification. Accordingly, we outline the steps required to provide several intervention measures, for example (i) collection and preservation of wild and cultivated kelp germplasm; (ii) selection of suitable cultivation sites under changing environmental conditions; (iii) developing stress‐resistant cultivars; and finally, (iv) adoption of innovative cultivation models. The review concludes with genome‐based, designs for molecular breeding and calls for the establishment of an East Asian Kelp Consortium (EAKC). Collectively, the Chinese kelp industry could provide beneficial goods and services, for example bioenergy to fine chemicals and environmental benefits, such as carbon capture, pH amelioration and provision of habitat for many other marine species of commercial value. The strategies proposed in this article thus have the potential to not only improve but also reinvigorate the kelp industry in China and nearby Japan and Korea, in the context of both environmental health and economic benefits.

Cover Image - Zi‐Min Hu; Ti‐Feng Shan; Jie Zhang; Quan‐Sheng Zhang; Alan T. Critchley; Han‐Gil Choi; Norishige Yotsukura; Fu‐Li Liu; De‐Lin Duan (Reviews in Aquaculture, 2021)
The cover image is based on the Review Article Kelp aquaculture in China: A retrospective and future prospects by Zi‐Min Hu et al., https://doi.org/10.1111/raq.12524 . image

Study on Microwave Heating Order and Electromagnetic Characteristics of Copper and Gold Ores - Feng Lin; Xia-Ting Feng; Gao-Ming Lu; Xiang-Xin Su; Shi-Ping Li; Jiu-yu Zhang (Rock Mechanics and Rock Engineering, 2021)

Experiments on granular flow behavior and deposit characteristics: implications for rock avalanche kinematics - Kun Li; Yu-Feng Wang; Qi-Wen Lin; Qian-Gong Cheng; Yue Wu (Landslides, 2021)

Genome-wide identification and expression analysis of the MADS-box transcription factor family in Camellia sinensis - Zai-Bao Zhang; Yuan-Jin Jin; Hou-Hong Wan; Lin Cheng; Zhi-Guo Feng (Journal of Applied Genetics, 2021)

Impact factors of the accumulation, migration and spread of antibiotic resistance in the environment - Zibo Lin; Tao Yuan; Lai Zhou; Sen Cheng; Xu Qu; Ping Lu; Qiyan Feng (Environmental Geochemistry and Health, 2021)

RETRACTED ARTICLE: Cost control model of marine crude oil pollutant degradation based on game analysis - Rongli Dun; Lin Xue; Jiaxiang Feng (Arabian Journal of Geosciences, 2021)

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage - Yang Cao; Yin Li; Chao He; Feng Yan; Jian-Ru Li; Hang-Zhe Xu; Jian-Feng Zhuang; Hang Zhou; Yu-Cong Peng; Xiong-Jie Fu; Xiao-Yang Lu; Yuan Yao; et al. (Neuroscience Bulletin, 2021)

GTree: an Open-source Tool for Dense Reconstruction of Brain-wide Neuronal Population - Hang Zhou; Shiwei Li; Anan Li; Qing Huang; Feng Xiong; Ning Li; Jiacheng Han; Hongtao Kang; Yijun Chen; Yun Li; Huimin Lin; Yu-Hui Zhang; et al. (Neuroinformatics, 2021)

Increased depression risk for elderly women with high blood levels of strontium and barium - Jia Lv; Yan-ling Li; Wen-qiang Ren; Rong Li; Jian-rong Chen; Chao Bao; Zhi-ping Du; Shun Feng; Ling Gu; Hui Gao; Kai-yong Liu; Lin-sheng Yang; et al. (Environmental Chemistry Letters, 2021)

Increased resting state functional irregularity of T2DM brains with high HbA1c: sign for impaired verbal memory function? - Xin Zhang; Ying Yu; Zhe-Sheng Shi; Ke Xu; Jia-Hao Feng; Ze-Yang Li; Xiang-Nan Zhang; Shu-Ning Shen; Yang Yang; Lin-Feng Yan; Jin Zhang; Qian Sun; et al. (Brain Imaging and Behavior, 2021)

miR-23b Attenuates LPS-Induced Inflammatory Responses in Acute Lung Injury via Inhibition of HDAC2 - Zhi-Feng Luo; Xiang-Hui Jiang; Huan Liu; Li-Yuan He; Xiong Luo; Fu-Chun Chen; Yu-Lin Tan (Biochemical Genetics, 2021)

The molecular mechanism of a novel derivative of BTO-956 induced apoptosis in human myelomonocytic lymphoma cells - Yu-Lin Li; De-Jun Zhou; Zheng-Guo Cui; Lu Sun; Qian-Wen Feng; Shahbaz Ahmad Zakki; Yusuke Hiraku; Cheng-Ai Wu; Hidekuni Inadera (Apoptosis, 2021)

New secondary metabolite with cytotoxicity from spawning soft coral Asterospicularia laurae in Taiwan - Jui-Hsin Su; Chih-I Liu; Mei-Chin Lu; Chi-I Chang; Min-Ying Hsieh; Yu-Chi Lin; Chang-Feng Dai; Ya-Han Zhang; Zheng-Yu Lin; Yun-Sheng Lin (Natural Product Research, 2021)

The Effect of Wave-Induced Current and Coastal Structure on Sediment Transport at the Zengwen River Mouth - Chun-Hung Pao; Jia-Lin Chen; Shih-Feng Su; Yu-Ching Huang; Wen-Hsin Huang; Chien-Hung Kuo (Journal of Marine Science and Engineering, 2021)
The mechanisms that control estuarine sediment transport are complicated due to the interaction between riverine flows, tidal currents, waves, and wave-driven currents. In the past decade, severe seabed erosion and shoreline retreat along the sandy coast of western Taiwan have raised concerns regarding the sustainability of coastal structures. In this study, ADCPs (Acoustic Doppler Current Profiler) and turbidity meters were deployed at the mouth of the Zengwen river to obtain the time series and the spatial distribution of flow velocities and turbidity during the base flow and flood conditions. A nearshore circulation model, SHORECIRC, has been adapted into a hybrid finite-difference/finite-volume, TVD (Total Variation Diminishing)-type scheme and coupled with the wave-spectrum model Simulating Waves Nearshore (SWAN). Conventional finite-difference schemes often produce unphysical oscillations when modeling coastal processes with abrupt bathymetric changes at river mouths. In contrast, the TVD-type finite volume scheme allows for robust treatment of discontinuities through the shock-capturing mechanism. The model reproduces water levels, waves, currents observed at the mouth of the Zengwen River reasonably well. The simulated residual sediment transport patterns demonstrate that the transport process at the river mouth is dominated by the interaction of the bathymetry and wave-induced currents when the riverine discharge was kept in reservoirs. The offshore residual transport causes erosion at the northern part of the river mouth, and the onshore residual transport causes accretion in the ebb tidal shoals around the center of the river mouth. The simulated morphological evolution displays significant changes on shallower deltas. The location with significant sea bed changes is consistent with the spot in which severe erosion occurred in recent years. Further analysis of morphological evolution is also discussed to identify the role of coastal structures, for example, the extension of the newly constructed groins near the river mouth.

Environmental Effects on the Spatiotemporal Variability of Fish Larvae in the Western Guangdong Waters, China - Yuting Feng; Lijun Yao; Hui Zhao; Jing Yu; Zhaojin Lin (Journal of Marine Science and Engineering, 2021)
Spawning grounds occupy an important position in the survival and reproduction of aquatic life, which plays an important role in the replenishment of fishery resources, especially in the China coasts where fishery resources are depleting. This study investigated environmental effects on the spatiotemporal variability of fish larvae in the western Guangdong waters (WGWs), on the basis of generalized additive models (GAMs) and center of gravity (CoG). Satellite data including sea surface salinity (SSS), sea surface temperature (SST), and in situ observations for fish larvae from April to June in 2014–2015 were used. Results showed that 40.3% of the total variation in fish larvae density was explained. SST, SSS, and depth showed positive effects in 23–24 °C and 27–30 °C, 24–32 PSU, and 0–60 m, and showed negative effects in 24–27 °C, 32–34.2 PSU, 60–80 m. Based on the stepwise GAMs, the most important factor was month, with a contribution of 10.6%, followed by longitude, offshore distance, depth, and latitude, with contributions of 7.0%, 7.0%, 6.3%, 4.2%, 3.9%, and 1.3%, respectively. Fish larvae CoG shifted northward by 0.6° N and eastwards by 0.13° E from April to June. The distribution of fish larvae in the WGWs was affected by complex submarine topography in the Qiongzhou Strait, coastal upwelling in the WGWs, and runoff from the Pearl River.

Modulatory effect of Tagetes erecta flowers essential oils via Nrf2/HO-1/NF-κB/p65 axis mediated suppression of N-methyl-Nʹnitro-N-nitroguanidine (MNNG) induced gastric cancer in rats - Guoliang Cui; Fei Wei; Muxin Wei; Liqun Xie; Zhenyan Lin; Xiaoke Feng (Molecular and Cellular Biochemistry, 2021)

Simulation of the fragmentation and propagation of jointed rock masses in rockslides: DEM modeling and physical experimental verification - Qi-wen Lin; Qian-Gong Cheng; Yu Xie; Feng-shou Zhang; Kun Li; Yu-feng Wang; Yuan-yuan Zhou (Landslides, 2021)

Phylogeny, recombination, and invasiveness of group B Streptococcus revealed by genomic comparisons of its global strains - Enze Lin; Shengmei Zou; Yue Wang; Chien-Chung Lee; Cheng-Hsun Chiu; Ye Feng (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis - Tsung-Ying Tsai; Li-Wei Lo; Shin-Huei Liu; Wen-Han Cheng; Yu-Hui Chou; Wei-Lun Lin; Yenn-Jiang Lin; Shih-Lin Chang; Yu-Feng Hu; Fa-Po Chung; Jo-Nan Liao; Tze-Fan Chao; et al. (Environmental Science and Pollution Research, 2021)

Remediation of contaminated soil and groundwater using chemical reduction and solidification/stabilization method: a case study - Shi-Feng Lu; Yu-Lin Wu; Zhan Chen; Tao Li; Chao Shen; Lin-Kang Xuan; Ling Xu (Environmental Science and Pollution Research, 2021)

Characterization and validation of QTLs for adult plant stripe rust resistance in Chinese wheat landrace Dabaimai - M. Y. Wang; M. R. Xu; F. T. Wang; S. J. A. Shah; J. Feng; R. M. Lin; S. C. Xu (Cereal Research Communications, 2021)

Small RNA Sequencing Analysis of Germinating Single-bud Seedcane Sett in Sugarcane - Kai-Chao Wu; Lin Xu; Zhi-Nian Deng; Tian Pang; Rong-Hua Zhang; Yi-Jie Li; Xiao-Yan Liu; Cheng-Feng Huang; Wen-Xian Qin; Jian-Feng Wei; Li-Ping Wei; Yang-Rui Li; et al. (Sugar Tech, 2021)

Roles of FERONIA-like receptor genes in regulating grain size and quality in rice - Long Wang; Dandan Wang; Zhuhong Yang; Shun Jiang; Jianing Qu; Wei He; Zhenming Liu; Junjie Xing; Youchu Ma; Qinlu Lin; Feng Yu (Science China Life Sciences, 2021)

Phylogenetic and ion-response analyses reveal a relationship between gene expansion and functional divergence in the Ca2+/cation antiporter family in Angiosperms - Ye Zheng; Lin-Bo Wang; Shu-Feng Sun; Shi-Ying Liu; Ming-Jia Liu; Juan Lin (Plant Molecular Biology, 2021)

ARF4 regulates shoot regeneration through coordination with ARF5 and IAA12 - Miao Miao Zhang; Huan Kai Zhang; Jun Feng Zhai; Xian Sheng Zhang; Ya Lin Sang; Zhi Juan Cheng (Plant Cell Reports, 2021)

Evaluation of geogenic cadmium bioavailability in soil-rice system with high geochemical background caused by black shales - Cong Zhong; Zixu Feng; Wei Jiang; Lin Xiao; Xinying Zhang; Yinjun Zhao; Qing Lin (Journal of Soils and Sediments, 2021)

Chronic Neck Pain Affects Shoulder Muscle Activity and Postural Control During Functional Reach - Cheng-Chieh Lin; Cheng-Feng Lin; Shiang-Hua Hua; Jen-Chieh Liao (Journal of Medical and Biological Engineering, 2021)

Inhibitory effects of novel 1,4-disubstituted 1,2,3-triazole compounds on quorum-sensing of P. aeruginosa PAO1 - Shuang Li; Yumin Zhang; Kai Jiang; Huiying Wang; Feng Lin (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Desorption of CO2, SO2, and NH3 in the vacuum evaporation of desulfurization wastewater - Guifang Chen; Xiaofei Sun; Yunqi Feng; Zhanlong Song; Lin Cui; Yanpeng Mao; Chunyuan Ma; Shouyan Chen (Environmental Science and Pollution Research, 2021)

Paracoccus lichenicola sp. nov., Isolated from Lichen - Lei Lang; De-Feng An; Long-Qian Jiang; Gui-Ding Li; Li-Song Wang; Xin-Yu Wang; Qin-Yuan Li; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2021)

Translocation and distribution of mercury in biomasses from subtropical forest ecosystems: evidence from stable mercury isotopes - Yi Liu; Che-Jen Lin; Wei Yuan; Zhiyun Lu; Xinbin Feng (Acta Geochimica, 2021)

The substrate‐dependent regulatory effects of the AfeI /R system in Acidithiobacillus ferrooxidans reveals the novel regulation strategy of quorum sensing in acidophiles - Xue‐Yan Gao; Chang‐Ai Fu; Likai Hao; Xiu‐Feng Gu; Rui Wang; Jian‐Qiang Lin; Xiang‐Mei Liu; Xin Pang; Cheng‐Jia Zhang; Jian‐Qun Lin; Lin‐Xu Chen (Environmental Microbiology, 2021)
Summary A LuxI/R‐like quorum sensing (QS) system (AfeI/R) has been reported in the acidophilic and chemoautotrophic Acidithiobacillus spp. However, the function of AfeI/R remains unclear because of the difficulties in the genetic manipulation of these bacteria. Here, we constructed different afeI mutants of the sulfur‐ and iron‐oxidizer A . ferrooxidans , identified the N‐acyl homoserine lactones (acyl‐HSLs) synthesized by AfeI, and determined the regulatory effects of AfeI/R on genes expression, extracellular polymeric substance synthesis, energy metabolism, cell growth and population density of A . ferrooxidans in different energy substrates. Acyl‐HSLs‐mediated distinct regulation strategies were employed to influence bacterial metabolism and cell growth of A . ferrooxidans cultivated in either sulfur or ferrous iron. Based on these findings, an energy‐substrate‐dependent regulation mode of AfeI/R in A . ferrooxidans was illuminated that AfeI/R could produce different types of acyl‐HSLs and employ specific acyl‐HSLs to regulate specific genes in response to different energy substrates. The discovery of the AfeI/R‐mediated substrate‐dependent regulatory mode expands our knowledge on the function of QS system in the chemoautotrophic sulfur‐ and ferrous iron‐oxidizing bacteria, and provides new insights in understanding energy metabolism modulation, population control, bacteria‐driven bioleaching process, and the coevolution between the acidophiles and their acidic habitats.

Sesquiterpenoids and meroterpenoids from a mangrove derived fungus Diaporthe sp. SCSIO 41011 - Xiao-Wei Luo; Chun-Mei Chen; Kun-Long Li; Xiu-Ping Lin; Cheng-Hai Gao; Xue-Feng Zhou; Yong-Hong Liu (Natural Product Research, 2021)

Comparison of the Nutritional Quality of Three Edible Tissues from Precocious and Normal Adult Female Chinese Mitten Crabs ( Eriocheir sinensis ) - Huafeng Cheng; Haoran Wu; Feng Liang; Mengtian Ge; Shaotong Jiang; Lin Lin; Jianfeng Lu (Journal of Aquatic Food Product Technology, 2021)

Neoproterozoic glaciations and rift evolution in the northwest Tarim Craton, China: new constraints from geochronological, geochemical, and geophysical data - Lin Wu; Shuwei Guan; Rong Ren; Chunyu Zhang; Xingqiang Feng (International Geology Review, 2021)

Understanding the dynamical-microphysical-electrical processes associated with severe thunderstorms over the Beijing metropolitan region - Xiushu Qie; Shanfeng Yuan; Zhixiong Chen; Dongfang Wang; Dongxia Liu; Mengyu Sun; Zhuling Sun; Abhay Srivastava; Hongbo Zhang; Jingyu Lu; Hui Xiao; Yongheng Bi; et al. (Science China Earth Sciences, 2021)

Simulating warmer and drier climate increases root production but decreases root decomposition in an alpine grassland on the Tibetan plateau - Huiying Liu; Li Lin; Hao Wang; Zhenhua Zhang; Zijian Shangguan; Xiaojuan Feng; Jin-Sheng He (Plant and Soil, 2021)

Memory impairment of chewing-side preference mice is associated with 5-HT-BDNF signal pathway - Hua Jiang; Hong Yin; Lin Wang; Chunzhen Feng; Yang Bai; Dongzong Huang; Qiao Zhang; Hongchen Liu; Yuan Hu (Molecular and Cellular Biochemistry, 2021)

LncRNA SNHG7 sponges miR-449a to promote pituitary adenomas progression - Xiongfei Yue; Ce Dong; Zhanying Ye; Lin Zhu; Xiaoyang Zhang; Xiaoyan Wang; Feng Mo; Zheng Li; Baogen Pan (Metabolic Brain Disease, 2021)