Lockdown-induced Urban Aerosol Change over Changchun, China During COVID-19 Outbreak with Polarization LiDAR - Weiwei Chen; Lingjian Duanmu; Yang Qin; Hongwu Yang; Jing Fu; Chengwei Lu; Wei Feng; Li Guo (Chinese Geographical Science, 2022)

Transport Patterns and Potential Sources of Atmospheric Pollution during the XXIV Olympic Winter Games Period - Yuting Zhang; Xiaole Pan; Yu Tian; Hang Liu; Xueshun Chen; Baozhu Ge; Zhe Wang; Xiao Tang; Shandong Lei; Weijie Yao; Yuanzhe Ren; Yongli Tian; et al. (Advances in Atmospheric Sciences, 2022)
The attainment of suitable ambient air quality standards is a matter of great concern for successfully hosting the XXIV Olympic Winter Games (OWG). Transport patterns and potential sources of pollutants in Zhangjiakou (ZJK) were investigated using pollutant monitoring datasets and a dispersion model. The PM 2.5 concentration during February in ZJK has increased slightly (28%) from 2018 to 2021, mostly owing to the shift of main potential source regions of west-central Inner Mongolia and Mongolian areas (2015–18) to the North China Plain and northern Shanxi Province (NCPS) after 2018. Using CO as an indicator, the relative contributions of the different regions to the receptor site (ZJK) were evaluated based on the source-receptor-relationship method (SRR) and an emission inventory. We found that the relative contribution of pollutants from NCPS increased from 33% to 68% during 2019–21. Central Inner Mongolia (CIM) also has an important impact on ZJK under unfavorable weather conditions. This study demonstrated that the effect of pollution control measures in the NCPS and CIM should be strengthened to ensure that the air quality meets the standard during the XXIV OWG.

A novel antisense long non‐coding RNA participates in asexual and sexual reproduction by regulating the expression of GzmetE in Fusarium graminearum - Jie Wang; Wenping Zeng; Jiatao Xie; Yanping Fu; Daohong Jiang; Yang Lin; Weidong Chen; Jiasen Cheng (Environmental Microbiology, 2022)

Origin and Implications of Pollution in Coastal Groundwater of the Guangdong Province - Chenzhe Li; Tengfei Fu; Yushan Fu; Zhenyan Wang; Bin Li; Chen Qi; Guangquan Chen; Xingyong Xu; Hongjun Yu (Journal of Marine Science and Engineering, 2022)
The groundwater resource is crucial to the urbanization and industrialization in the Guangdong coastal area; the rapid development of Daya Bay has presented a challenge for the management of the groundwater quantity and quality. Therefore, a novel approach to hydrochemical analysis, which, combined with the health risk model and the water quality index (WQI), was used to explain the hydrochemistry characteristics and risks to human health of groundwater in the Guangdong coastal areas in addition to investigating the factors controlling groundwater quality. The results showed that the average concentration of total dissolved solids (TDS) in groundwater was 1935.26 mg/L and the quality of water was weakly alkaline. The dominant hydrochemical types of groundwater were identified to be Mg-HCO3 and Na-Cl·HCO3. The main factor influencing the hydrochemical composition was rock weathering, while the result of principal component analysis (PCA) shows seawater intrusion and anthropogenic inputs also have an effect on the water quality. The conclusions of the water quality assessment indicated that most of the groundwater samples were acceptable for drinking. However, both WQI and the non-carcinogenic hazard quotient (HQ) values indicated unacceptable risks in any area of Maoming, Zhanjiang and Shantou, and, according to the hazard index (HI) value, children in the study area are at more danger to health risks than adults. It is suggested that both groundwater salinization and nitrate pollution should be paid attention to when improving groundwater quality and exploring the sustainable utilization of groundwater resources.

Sustainable Approaches to Realize Carbon Neutrality in China: A Case Study of Zhejiang Province - Yuexuan Shu; Jiwei Chen; Yifan Huang; Weiqi Fu (Journal of Marine Science and Engineering, 2022)
With the continuous development of industry, the massive emission of carbon dioxide (CO2) has become a global challenge that cannot be ignored due to its nature as the primary driver of global climate change and environmental crisis. Carbon neutrality is proposed as a global initiative to mitigate climate change. As a developing industrial country, China provides about one-third of global carbon emissions and has set a carbon-neutral goal by 2060. To achieve this goal, continuous efforts across the country are required. In this review, Zhejiang Province, one of the most developed regions in China, is set as a model for analysis. We first summarize the current situation of carbon emission in Zhejiang Province. Then, corresponding sustainable approaches such as ecological and industrial solutions for the reduction of future carbon emissions are introduced for Zhejiang Province. We also provide a direction for the realization of carbon neutrality, focusing on the most promising solutions for Zhejiang Province.

Quantifying the associations of the air pollutant SO2 on outpatient visits for conjunctivitis in Hangzhou, China - Zhijian Chen; Qiuli Fu; Lizhi Wu; Peiwei Xu; Dandan Xu; Xuejiao Pan; Xiaoming Lou; Xiaofeng Wang; Ke Yao; Zhe Mo (Environmental Science and Pollution Research, 2022)

Effects of CYP24A1 polymorphisms on premature ejaculation: a case–control study - Fei Wang; Defan Luo; Jianxiang Chen; Cuiqing Pan; Zhongyao Wang; Housheng Fu; Jiangbing Xu; Meng Yang; Shaowei Mo; Liying Zhuang; Weifu Wang (Journal of Genetics, 2022)

Recent advances in alleviating food allergenicity through fermentation - Xiaowen Pi; Yili Yang; Yuxue Sun; Qiang Cui; Yin Wan; Guiming Fu; Hongbing Chen; Jianjun Cheng (Critical Reviews in Food Science and Nutrition, 2022)

METTL3 promotes m6A hypermethylation of RBM14 via YTHDF1 leading to the progression of hepatocellular carcinoma - Jingyao Hu; Liang Yang; Xueqiang Peng; Minghuan Mao; Xiaodan Liu; Jianbo Song; Hangyu Li; Fu Chen (Human Cell, 2022)

Horizontal and vertical heterogeneity of sediment microbial community in Site F cold seep, the South China Sea - Xinyi Zhai; Xiaochong Shi; Haojin Cheng; Peng Yao; Bin Zhao; Lin Chen; Jiwen Liu; Lei Cao; Minxiao Wang; Lulu Fu; Xiao-Hua Zhang; Min Yu (Frontiers in Marine Science, 2022)
Site F is the most vigorous cold seep known on the continental slope of the northern South China Sea. Up to now, the microbial community structures in sediments of Site F based on the high-throughput sequencing of the 16S rRNA genes have been studied extensively. However, few studies investigated the microbial community structures at fine vertical scales of Site F and control stations outside Site F. In this study, a comprehensive investigation of microbial communities in sediments of Site F along the depths varying from 0 to 24 cm below sea floor (cmbsf) of four sampling sites—SRS (Southern Reduced Sediment), NRS (Northern Reduced Sediment), Control 1 (close to Site F), and Control 2 (far from Site F)—was carried out. The high relative abundances of anaerobic methanotrophic archaea (ANME), Desulfobacterota [sulfate-reducing bacteria (SRB)], and Campylobacteria [sulfur-oxidizing bacteria (SOB)] in SRS and NRS indicated that these two sites were newborn cold seep sites compared with non-seep sites, Control 1, and Control 2. A positive correlation between ANME-1b, ANME-2, and SEEP-SRB and an enrichment of Sulfurovum and Methlomonadaceae were found in the surface sediments of both SRS and NRS, indicating that the processes of anaerobic oxidation of methane (AOM), sulfur oxidation, and sulfate reduction might occur in seep sites. SRS was enriched with ANME-1b and SEEP-SRB2 with a proposed sulfate-methane transition zone (SMTZ) approximately located at 8 cmbsf. The high abundance of ANME in SRS may due to the high concentration of methane. NRS was enriched with ANME-2, Desulfatiglans , Sulfurovum , and Methanosarcinaceae with a proposed SMTZ at about 10 cmbsf. According to the analyses of microbial community structure and environmental factors, NRS could be described as a notable cold seep reduced sediment site with low sulfate and high H 2 S that nourished abundant SEEP-SRB1, ANME-2, Methanosarcinales , and Sulfurovum , which showed similar distribution pattern. Our study expands the current knowledge on the differences of microbial communities in cold seep sites and non-seep sites and sheds light on the horizontal and vertical heterogeneity of sediment microbial community in Site F.

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

Stat5−/− CD4+ T cells elicit anti-melanoma effect by CD4+ T cell remolding and Notch1 activation - Ke Jin; Tong Li; Zhiyong Miao; Jingjing Ran; Luyu Chen; Dachao Mou; Chuang Wang; Shasha Wu; Hanshuo Yang; Xin-Yuan Fu (Science China Life Sciences, 2022)

The Sea Level Fingerprints of Global Terrestrial Water Storage Changes Detected by GRACE and GRACE-FO Data - Jianwei Sun; Linsong Wang; Zhenran Peng; Zhenyan Fu; Chao Chen (Pure and Applied Geophysics, 2022)

Novel circularRNA circ-0047078 promotes pancreatic ductal adenocarcinoma progression through mircoRNA miR-11181— Chemokine (C-X-C motif) Ligand 12/Melanoma Cell Adhesion Molecule/Regulator of G-protein signaling 16 pathway - Yuzhou Wang; Hangwei Fu; Yan Jiang; Bo Zhou; Ping Chen (Molecular Biology Reports, 2022)

Identification and validation of suitable reference genes for quantitative real-time PCR studies in Adiantum reniforme var. sinense - Qi Fu; Lin Xiang; Kai-ge Zhao; Long-qing Chen (Journal of Plant Biochemistry and Biotechnology, 2022)

Effects of tuber size and burial depth on germination and plant growth of the submerged macrophyte Vallisneria spinulosa S.Z. Yan at different light intensities - Guixiang Yuan; Lijun Sun; Peiqin Guo; Zhenglong Chen; Zhenzhi Yang; Hui Fu; Erik Jeppesen (Hydrobiologia, 2022)

Household solid fuel use with diabetes and fasting blood glucose levels among middle-aged and older adults in China - Yuxiong Chen; Siqin Feng; Zhen’ge Chang; Yakun Zhao; Jia Fu; Yijie Liu; Siqi Tang; Yitao Han; Yanbo Liu; Yuanxun Zhang; Shuyang Zhang; Zhongjie Fan (Environmental Science and Pollution Research, 2022)

Impacts of Mercury Exposure Levels and Sources on the Demethylation of Methylmercury Through Human Gut Microbiota - Xian-Feng Yang; Shao-Chen Yang; Fu-Li Wen; Lin Feng; Bo Meng; Hai-Yan Hu; Bao-Lin Wang; Jun Li; Alexandre J. Poulain; Ping Li (Bulletin of Environmental Contamination and Toxicology, 2022)

Shaking table test and numerical analysis of single-layer reticulated domes with or without three-dimensional isolation bearing - Gui-Bo Nie; Dong-fang Li; Xu-dong Zhi; Fu-yang Wang; Chen-xiao Zhang (Bulletin of Earthquake Engineering, 2022)

Endothelial cells induce degradation of ECM through enhanced secretion of MMP14 carried on extracellular vesicles in venous malformation - Gao-Hong Chen; Jie-Gang Yang; Hou-Fu Xia; Lin-Zhou Zhang; Yin-Hsueh Chen; Kui-Ming Wang; Xu Duan; Lian-Zhi Wu; Yi-Fang Zhao; Gang Chen (Cell and Tissue Research, 2022)

Accurate detection method of high-density polyethylene film leakage location based on secondary electric potential difference - Fu-Yu Jiang; Pei-Xuan Qiao; Li-Kun Gao; Hai-Jun Chen (Applied Geophysics, 2022)

Potential millennial‐scale avian declines by humans in southern China - Feng Dong; Qiang Zhang; Yi‐Lin Chen; Fu‐Min Lei; Shou‐Hsien Li; Fei Wu; Xiao‐Jun Yang (Global Change Biology, 2022)
Mounting observational records demonstrate human‐caused faunal decline in recent decades, while accumulating archaeological evidence suggests an early biodiversity impact of human activities during the Holocene. A fundamental question arises concerning whether modern wildlife population declines began during early human disturbance. Here, we performed a population genomic analysis of six common forest birds in East Asia to address this question. For five of them, demographic history inference based on 25–33 genomes of each species revealed dramatic population declines by 4‐ to 48‐fold over millennia (e.g. 2000–5000 thousand years ago). Nevertheless, summary statistics detected nonsignificant correlations between these population size trajectories and Holocene temperature variations, and ecological niche models explicitly predicted extensive range persistence during the Holocene, implying limited demographic consequence of Holocene climate change. Further analyses suggest high negative correlations between the reconstructed population declines and human disturbance intensities and indicate a potential driver of human activities. These findings provide a deep‐time and large‐scale insight into the recently recognized avifaunal decline and support an early origin hypothesis of human effects on biodiversity. Overall, our study sheds light on the current biodiversity crisis in the context of long‐term human–environment interactions and offers a multi‐evidential framework for quantitatively assessing the ecological consequences of human disturbance.

Exploiting the gut microbiota to predict the origins and quality traits of cultured sea cucumbers - Zelong Zhao; Jingwei Jiang; Jie Zheng; Yongjia Pan; Ying Dong; Zhong Chen; Shan Gao; Yao Xiao; Pingzhe Jiang; Xuda Wang; Gaohua Zhang; Bai Wang; et al. (Environmental Microbiology, 2022)
Summary Nowadays, the true economic and nutritional value of food is underpinned by both origin and quality traits, more often expressed as increased quality benefits derived from the origin source. Gut microbiota contribute to food metabolism and host health, therefore, it may be suitable as a qualifying indicator of origin and quality of economic species. Here, we investigated relationships between the gut microbiota of the sea cucumber ( Apostichopus japonicus ), a valuable aquaculture species in Asia, with their origins and quality metrics. Based on data from 287 intestinal samples, we generated the first biogeographical patterns for A . japonicus gut microbiota from origins across China. Importantly, A . japonicus origins were predicted using the random forest model that was constructed using 20 key gut bacterial genera, with 97.6% accuracy. Furthermore, quality traits such as saponin, fat and taurine were also successfully predicted by random forest models based on gut microbiota, with approximately 80% consistency between predicted and true values. We showed that substantial variations existed in the gut microbiota and quality variables in A . japonicus across different origins, and we also demonstrated the great potential of gut microbiota to track A . japonicus origins and predict their quality traits.

Life cycle assessment of auto-tropically cultivated economic microalgae for final products such as food, total fatty acids, and bio-oil - Dan Zhang; Siyuan An; Rao Yao; Wen Fu; Yujie Han; Ming Du; Zixi Chen; Anping Lei; Jiangxin Wang (Frontiers in Marine Science, 2022)
Life cycle assessment (LCA) is a powerful tool to evaluate environmentally sustainable production or consumption of various goods or services. Microalgae are single-celled green factories and good resources of biofuels, bioactive products, food ingredients, and degradable biomaterials. Currently, microalgae are also valuable for mitigating elevated greenhouse gases like CO 2 levels and treatment of wastewater. LCA evaluation was limited and separated, majorly in microalgal biofuels and heterotrophic cultivation. Comparative LCA for different final algal products such as algal powder, bio-oil, total fatty acid, and residue recycling is still limited, especially autotrophic algal cultivation for products other than bio-oils and biofuels. Thus, we chose several autotrophic cultivated microalgae and made a comparative LCA among these selected species and a detailed step-by-step production in Chlorella sp. Results indicated that we could significantly reduce the production cost and lower environmental impacts by selecting algal species and final products, optimizing methods for algal cultivation, biomass separation, and drying process, and land selection plus electricity renewable energy, together with thermal power plants nearby for CO 2 or flu gas. It shed light on the insight of microalgal consumption selection under current international requirements and challenges for carbon sequestration.

Correction to: Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice - Xiongjie Fu; Hanhai Zeng; Jikuang Zhao; Guoyang Zhou; Hang Zhou; Jianfeng Zhuang; Chaoran Xu; Jianru Li; Yucong Peng; Yang Cao; Yin Li; Huaijun Chen; et al. (Translational Stroke Research, 2022)

Taurine supplementation improves hippocampal metabolism in immature rats with intrauterine growth restriction (IUGR) through protecting neurons and reducing gliosis - Qiong Fang; Jing Liu; Lang Chen; Qiaobin Chen; Yan Wang; Zuanfang Li; Wei Fu; Ying Liu (Metabolic Brain Disease, 2022)

Role of host plants in the suitability and dispersal of an omnivorous predator Arma chinensis Fallou (Hemiptera: Pentatomidae: Asopinae) in a biological control context - Ming-Zhen Pan; Zhi-Xiao Fu; Yu-Yan Li; Hong-Yin Chen; Li-Sheng Zhang; Tong-Xian Liu (Journal of Plant Diseases and Protection, 2022)

Ginsenoside Rb3 attenuates skin flap ischemia-reperfusion damage by inhibiting STING-IRF3 signaling - Yuanbin Li; Haifen Liu; Zhaohui Zeng; Hui Lin; Xin Chen; Xianglian Yuan; Jizhe Qiu; Fengchun Fu; Zhuang Chen; Jianjun Kuang (Journal of Molecular Histology, 2022)

Biomechanical Analysis of the External Fixation in a Lumbar Fracture Model: A Finite Element Study - Yijia Liao; Yiguo Yan; Yu Kang; Wenjun Wang; Xizheng Song; Wen Peng; Haibin Fu; Huarong Chen; Cheng Wang (Journal of Medical and Biological Engineering, 2022)
Purpose This study aimed to investigate the biomechanical characteristics of the external spinal fixation for treating lumbar fracture through finite element analysis (FEA) and provide a theoretical basis for its further application. Methods Two different models of L3 fracture fixed with the external spinal fixation and the internal fixation system respectively were constructed. The ROM, maximum stresses at L3, and the screws of the two models were measured under load control. Subsequently, the applied torque, the maximum stressed at L3, L1/2, L2/3, L3/4, L4/5 discs and the screws were analyzed under displacement control. Results Under load control, the external fixation model reserved more ROM than the internal fixation model (40.4–48.0% vs 30.5–41.0%). Compared to the internal fixation model, the maximum stresses at L3 and screws in the external fixation model were increased. Under displacement control, the external fixation model required fewer moments (N·mm) than the internal fixation model (flexion: 7500 vs 12,294; extension: 7500 vs 9027). Further, the maximum stresses at L3 and the screws in the external fixation model were greater than those of the internal fixation model, while the maximum stresses at the upper and lower adjacent discs of fixed segments were less than the internal fixation model. Conclusion Compared to the internal fixation system, the external fixation has a better stress distribution with the greater overall mobility. It theoretically reduces the stress concentration of the adjacent discs and the stress shielding of the fractured vertebral body.

Awareness for Endoscopic Screening Among Accompanying Children of Hospitalized Esophageal Cancer Patients in Henan - Lian Qun Zhang; Xian Juan Du; Fu You Zhou; Pei Nan Chen; Hai Ling Wang; Li Sun; Xiu Ling Li (Journal of Cancer Education, 2022)

Identification of the TF-miRNA-mRNA co-regulatory networks involved in sepsis - Xiaoqian Luo; Weina Lu; Jianfeng Zhao; Jun Hu; Enjiang Chen; Shi Fu; Qinghui Fu (Functional & Integrative Genomics, 2022)

Hypoxia-induced oxidative stress and apoptosis in gills of scaleless carp (Gymnocypris przewalskii) - FuJu Chen; Xiaodong Ling; YuTian Zhao; ShengYun Fu (Fish Physiology and Biochemistry, 2022)

Swift reduction of nitroaromatics by gold nanoparticles anchored on steam-activated carbon black via simple preparation - Yukui Fu; Cui Lai; Wenjing Chen; Huan Yi; Xigui Liu; Xiuqin Huo; Weicheng Cao; Zhuotong Zeng; Lei Qin (Environmental Science and Pollution Research, 2022)

Mutation of rpoS is Beneficial for Suppressing Organic Acid Secretion During 1,3-Propandiol Biosynthesis in Klebsiella pneumoniae - Shufan Dong; Xuxia Liu; Tianyu Chen; Xiaoqin Zhou; Shengming Li; Shuilin Fu; Heng Gong (Current Microbiology, 2022)

Responses of Labile Organic Carbon and Extractable Cadmium Fractions in an Agricultural Soil Following Long-Term Repeated Application of Pig Manure and Effective Microbes - Shaocheng Si; Yuan Li; Chen Tu; Yucheng Wu; Chuancheng Fu; Shuai Yang; Yongming Luo (Bulletin of Environmental Contamination and Toxicology, 2022)

Lead Exposure in Developmental Ages Promotes Aβ Accumulation by Disturbing Aβ Transportation in Blood-Cerebrospinal Fluid Barrier/Blood–Brain Barriers and Impairing Aβ Clearance in the Liver - Can-Can Zhou; Xu-Jie Wang; Zi-Chen Li; Wen-Jie Lu; Yun-Ting Zhang; Fu-Ming Shen; Dong-Jie Li (Biological Trace Element Research, 2022)

Selenide Chitosan Sulfate Improved the Hepatocyte Activity, Growth Performance, and Anti-oxidation Capacity by Activating the Thioredoxin Reductase of Chickens In Vitro and In Vivo - Lele Hou; Huiling Qiu; Lianqin Zhu; Shansong Gao; Fu Chen (Biological Trace Element Research, 2022)

Reliable reference genes for qPCR normalization in females of the mirid predator, Cyrtorhinus lividipennis (Hemiptera: Miridae) - Kui Hu; Ke Chen; Baobao Fu; Jianqi Liu; Yan Li; Qinjian Pan; Fang Liu (Biologia, 2022)

Study on Acoustic Emission Characteristics and Damage Mechanism of Mixed Aggregate Cemented Backfill Under Uniaxial Compression - Chen Guan; Ye Yicheng; Yao Nan; Fu Fanghui; Hu Nanyan (Arabian Journal of Geosciences, 2022)

Fengyun-4 Geostationary Satellite-Based Solar Energy Nowcasting System and Its Application in North China - Chunlin Huang; Hongrong Shi; Ling Gao; Mengqi Liu; Qixiang Chen; Disong Fu; Shu Wang; Yuan Yuan; Xiang’ao Xia (Advances in Atmospheric Sciences, 2022)

Soil moisture regulates warming responses of autumn photosynthetic transition dates in subtropical forests - Yongshuo H. Fu; Xinxi Li; Shouzhi Chen; Zhaofei Wu; Jianrong Su; Xing Li; Shuaifeng Li; Jing Zhang; Jing Tang; Jingfeng Xiao (Global Change Biology, 2022)
Autumn phenology plays a key role in regulating the terrestrial carbon and water balance and their feedbacks to the climate. However, the mechanisms underlying autumn phenology are still poorly understood, especially in subtropical forests. In this study, we extracted the autumn photosynthetic transition dates (APTD) in subtropical China over the period 2003–2017 based on a global, fine‐resolution solar‐induced chlorophyll fluorescence (SIF) dataset (GOSIF) using four fitting methods, and then explored the temporal–spatial variations of APTD and its underlying mechanisms using partial correlation analysis and machine learning methods. We further predicted the APTD shifts under future climate warming conditions by applying process‐based and machine learning‐based models. We found that the APTD was significantly delayed, with an average rate of 7.7 days per decade, in subtropical China during 2003–2017. Both partial correlation analysis and machine learning methods revealed that soil moisture was the primary driver responsible for the APTD changes in southern subtropical monsoon evergreen forest (SEF) and middle subtropical evergreen forest (MEF), whereas solar radiation controlled the APTD variations in the northern evergreen‐broadleaf deciduous mixed forest (NMF). Combining the effects of temperature, soil moisture and radiation, we found a significantly delayed trend in APTD during the 2030–2100 period, but the trend amplitude (0.8 days per decade) was much weaker than that over 2003–2017. In addition, we found that machine learning methods outperformed process‐based models in projecting APTD. Our findings generate from different methods highlight that soil moisture is one of the key players in determining autumn photosynthetic phenological processes in subtropical forests. To comprehensively understand autumn phenological processes, in‐situ manipulative experiments are urgently needed to quantify the contributions of different environmental and physiological factors in regulating plants' response to ongoing climate change.

Application of load transfer method for bored pile in loess area - Zhijun Zhou; Zhipeng Zhang; Chaoran Chen; Fu Xu; Tianyu Xu; Linxuan Zhu; Tong Liu (European Journal of Environmental and Civil Engineering, 2022)

Application of an improved hollow fiber liquid phase microextraction technique coupled to LC-MS/MS to studying migration of fluorescent whitening agents from plastic food contact materials - Wen-Li Zhou; Li Ding; Yun-Hui Cheng; Zhou Xu; Mao-Long Chen; Xian-Shu Fu (Food Additives & Contaminants: Part A, 2022)

Increased water vapor supply in winter and spring leading to the arid Central Asian wetting in last 6000 years - Xu Zhang; Bo Liu; Shengqian Chen; Zhenhao Fu; Tingting Xie; Fahu Chen (Science China Earth Sciences, 2022)

Divergent responses of fine root decomposition to removal of understory plants and overstory trees in subtropical Eucalyptus urophylla plantations - Yuanqi Chen; Yanju Zhang; Jianbo Cao; Shenglei Fu; Jun Wang; Hans Lambers; Zhanfeng Liu (Plant and Soil, 2022)

Lipofundin mediates major inhibition of intravenous propofol on phorbol myristate acetate and Escherichia coli-induced neutrophil extracellular traps - Ming-Shan Chen; Kung-Ssu Yang; Wen-Chun Lin; Chien-Liang Fang; Hsin-Fu Chen; Shew-Meei Sheu (Molecular Biology Reports, 2022)

Dioxin emission and distribution from cement kiln co-processing of hazardous solid waste - Wen-Wen Ye; Peng-Tao Cai; Ming-Xiu Zhan; Wen-Tao Jiao; Xu-Xu; Jian-Ying Fu; Tong Chen; Xiao-Dong Li (Environmental Science and Pollution Research, 2022)

The characteristics of ambient air quality in urban forest areas and other urban areas of Fuzhou city, China - Weicong Fu; Yuxuan Qiao; Chenxi Que; Hongkui Chen; Emily Dang; Jianwen Dong; Shuangyi Lin (Environment, Development and Sustainability, 2022)

Brevibacillus dissolubilis sp. nov., Isolated from Fresh Water - Wei Li; Zhao-Xuan Wang; Fu Ma; Zhi-Da Zi; Han-Yi Chen; De Zhou; Jie Lv (Current Microbiology, 2022)

Study on Iron Extraction from High Iron Bauxite Residue by Pyrite Reduction - HuiJun Fu; GuoZhi Lv; Ting-an Zhang; Xi Chao; Yang Chen (Bulletin of Environmental Contamination and Toxicology, 2022)

Influence of asymmetric blockage of the drainage system of a deep-buried tunnel on water gushing - He-lin Fu; Peng-tao An; Yi-min Wu; Jie Li; Long Chen (Journal of Mountain Science, 2022)

Oct4 facilitates chondrogenic differentiation of mesenchymal stem cells by mediating CIP2A expression - Lexiang Li; Qiwei Fu; Jiahua Shao; Bo Wang; Zheru Ding; Shuai Yuan; Jinhui Peng; Wei Xin; Jun Zhu; Yi Chen (Cell and Tissue Research, 2022)

Classification and source of crude oil in the Linhe Depression, Hetao Basin - Rongqian Zhao; Shijia Chen; Xiaoyan Fu; Zhitong He (Arabian Journal of Geosciences, 2022)

Impacts of Topographic Complexity on Modeling Moisture Transport and Precipitation over the Tibetan Plateau in Summer - Gudongze Li; Haoming Chen; Mingyue Xu; Chun Zhao; Lei Zhong; Rui Li; Yunfei Fu; Yanhong Gao (Advances in Atmospheric Sciences, 2022)
The non-hydrostatic global variable resolution model (MPAS-atmosphere) is used to conduct the simulations for the South Asian Summer monsoon season (June, July, and August) in 2015 with a refinement over the Tibetan Plateau (TP) at the convection-permitting scale (4 km). Two experiments with different topographical datasets, complex (4-km) and smooth (60-km) topography, are designed to investigate the impacts of topographical complexity on moisture transport and precipitation. Compared with the observations and reanalysis data, the simulation can successfully capture the general features of key meteorological fields over the TP despite slightly underestimating the inflow through the southern TP. The results indicate that the complex topography can decrease the inward and outward moisture transport, ultimately increasing the total net moisture transport into the TP by ∼11%. The impacts of complex topography on precipitation are negligible over the TP, but the spatial distributions of precipitation over the Himalayas are significantly modulated. With the inclusion of complex topography, the sharper southern slopes of the Himalayas shift the lifted airflow and hence precipitation northward compared to the smooth topography. In addition, more small-scale valleys are resolved by the inclusion of complex topography, which serve as channels for moisture transport across the Himalayas, further favoring a northward shift of precipitation. Overall, the difference between the two experiments with different topography datasets is mainly attributed to their differing representation of the degree of the southern slopes of the Himalayas and the extent to which the valleys are resolved.

Optimizing Hard Clam Production in Taiwan by Accounting for Nonlinear Effects of Stocking Density and Feed Costs on Farm Output of Clams - Jie-Min Lee; Sheng-Hung Chen; Yi-Chung Lee; Jung-Fu Huang; Christian Schafferer; Chun-Yuan Yeh; Ti-Wan Kung (Fishes, 2022)
Despite mass mortality, hard clams remain among the main cultured shellfish in Taiwan. Using cross-sectional data, this study applies threshold regression modeling with stocking density and feed costs as the threshold variables to explore the nonlinear relationship between input and output factors. The findings show that the production output levels may be increased by different combinations of factor inputs and variations in input factors. More specifically, the higher output levels may be achieved by increasing labor input while reducing capital input factors in farming households with a higher stocking density (HSD > 1,087,870 inds/ha) or higher feed cost (HFC > 13,889 NTD/ha). Farming households with a lower stocking density (LSD ≤ 1,087,870 inds/ha) may enhance production output levels by increasing feed input while reducing capital inputs. Moreover, the maximum output level of HSD and HFC farming households was estimated to reach 9255 kg/ha and 9807 kg/ha, respectively. Results of the production output simulation suggest that the feeding cost per hectare in LSD households should not exceed 25,119 NTD to avoid overfeeding, which may cause culture deterioration and lower survival rates. As such, farmers are advised to adjust their feed costs according to the stocking density to maximize production output.

Super droughts over East Asia since 1960 under the impacts of global warming and decadal variability - Lin Wang; Wen Chen; Qiang Fu; Gang Huang; Qiulin Wang; Chakrit Chotamonsak; Atsamon Limsakul (International Journal of Climatology, 2022)
In the last decade, a sequence of once‐in‐50 year or even once‐in‐100 year high‐impact drought events have hit East Asia. By defining a super drought with the Standardized Precipitation Evaporation Index for the time scales of 3, 6, 12 and 24 months all below −1.5, this study aims to examine the changes in super droughts and the underlying mechanism over East Asia in the past 60 years, putting the recent high‐impact droughts in the context. Super droughts in the last 10 years over East Asia have been the most expansive, with two hotspots located in the Transitional Climate Zone (TCZ) and the Southeast Asian region (SEA) regions, together accounting for 2/3 of the total. The seasonal distribution characterizes the largest contribution from summer followed by autumn and then spring and winter. Super droughts over TCZ peak in the recent two decades, which are primarily driven by the increase in potential evaporation (PET) contributing 41 and 80% in the first and second 10 years, respectively. It turns out that global warming signal can explain more than 90% of this PET increase. Over SEA, the recent decade and the period around 1990 saw the most widespread super droughts that were not spatially uniformly distributed but clustered in three subregions. Different from TCZ, the precipitation rather than PET is the most influential in governing super droughts over SEA. Out of the total variability in precipitation, about half of the super droughts in the recent decade is caused by decadal variability, while the trend mode has negligible influence.

Large-scale triaxial experiments on the static and dynamic behavior of an artificially cemented gravel material - Zhongzhi Fu; Shengshui Chen; Huaqiang Han (European Journal of Environmental and Civil Engineering, 2022)

Directed evolution of the PobR allosteric transcription factor to generate a biosensor for 4-hydroxymandelic acid - YaoYao Liang; Juan Luo; Chenhao Yang; Shuning Guo; Bowen Zhang; Fengqianrui Chen; Kairui Su; Yulong Zhang; Yi Dong; Zhihao Wang; Hongda Fu; Guangchao Sui; et al. (World Journal of Microbiology and Biotechnology, 2022)

Screening of Upstream Transcript Factors of IbMYB1-1 by Yeast One-hybrid in Purple-fleshed Sweet Potato - Danwen Fu; Yake Hui; Yahui Chen; Shaohua Yang; Feng Gao (Tropical Plant Biology, 2022)

Pathogen-associated T follicular helper cell plasticity is critical in anti-viral immunity - Han Feng; Xiaohong Zhao; Jenny Xie; Xue Bai; Weiwei Fu; Hairong Chen; Hong Tang; Xiaohu Wang; Chen Dong (Science China Life Sciences, 2022)

An ortholog of the MADS-box gene SEPALLATA3 regulates stamen development in the woody plant Jatropha curcas - Mei-Li Zhao; Zhi-Fang Zhou; Mao-Sheng Chen; Chuan-Jia Xu; Zeng-Fu Xu (Planta, 2022)

Ectopic Expression of Maize Plastidic Methionine Sulfoxide Reductase ZmMSRB1 Enhances Salinity Stress Tolerance in Arabidopsis thaliana - Guangling Wang; Xiaoyi Fu; Wanmei Zhao; Mengmeng Zhang; Fanguo Chen (Plant Molecular Biology Reporter, 2022)

Soil types determine vegetation communities along a toposequence in a dolomite peak-cluster depression catchment - Qingmei Meng; Sheng Wang; Zhiyong Fu; Yusong Deng; Hongsong Chen (Plant and Soil, 2022)

A Deep Mesencephalic Nucleus Circuit Regulates Licking Behavior - Di Zheng; Jia-Yu Fu; Meng-Yu Tang; Xiao-Dan Yu; Yi Zhu; Chen-Jie Shen; Chun-Yue Li; Shi-Ze Xie; Shan Lin; Minmin Luo; Xiao-Ming Li (Neuroscience Bulletin, 2022)

TREM-2 mediates dendritic cell–induced NO to suppress Th17 activation and ameliorate chronic kidney diseases - Ching-Cheng Lin; Ti-Yung Chang; Yong-Chen Lu; Yun-Syuan Wu; Wei Huang; Wei-Chi Lo; Guan-Fu Liu; Wei-Chan Hsu; Pamela S. Ohashi; Tak W. Mak; Jong-Ling Fuh; Hui-Chen Chen; et al. (Journal of Molecular Medicine, 2022)

Field engineering application of agricultural farmland surface runoff pollution treatment by combined bioreactor and constructed wetlands - H. Luo; X. Li; Y. Chen; X. Liu; K. Zhang; X. Fu; B. Jiang; R. Xue; J. Yang; M. Li; X. Li; W. Chen; et al. (International Journal of Environmental Science and Technology, 2022)

Differences in Rice Productivity and Growth Attributes Under Different Paddy-Upland Cropping Systems - Wei Zhou; Tao Wang; Yong Fu; Zhiping Yang; Qi Liu; Fengjun Yan; Yong Chen; Youfeng Tao; Wanjun Ren (International Journal of Plant Production, 2022)

Chronology, geochemical characteristics, and tectonic implications of a Triassic complex in the Rongma Area, Southern Qiangtang, Tibet - Zheng-Zhe Fan; Quan Wang; Xian Chen; Gen-Hou Wang; Yue Fu; Gui-Juan Guo (International Journal of Earth Sciences, 2022)

Advances in multiplex molecular detection technologies for harmful algae - Hanyu Fu; Chunyun Zhang; Yuanyuan Wang; Guofu Chen (Environmental Science and Pollution Research, 2022)

Astragalus Polysaccharides Reduce High-glucose-induced Rat Aortic Endothelial Cell Senescence and Inflammasome Activation by Modulating the Mitochondrial Na+/Ca2+ Exchanger - Xin-Yu Miao; Xiao-Xiao Zhu; Zhao-Yan Gu; Bo Fu; Shao-Yuan Cui; Yuan Zu; Ling-Jun Rong; Fan Hu; Xiang-Mei Chen; Yan-Ping Gong; Chun-Lin Li (Cell Biochemistry and Biophysics, 2022)

Comparison of the Macrozoobenthic Community and Sedimentary Environment with and Without Horseshoe Crab Presence in the Crocodile Island Intertidal Zone, Xiamen, China - Lizhe Cai; Xiaoyu Zhao; Wenqing Peng; Jingxiang Lin; Deyuan Yang; Yiyong Rao; Sujing Fu; Xinwei Chen; Wenzhi Cao (Journal of Ocean University of China, 2022)

Effects of postnatal exposure to tetrabromobisphenol A on testis development in mice and early key events - Yuanyuan Li; Mengqi Dong; Yiming Xiong; Qing Chang; Xuanyue Chen; Xufeng Fu; Xinghong Li; Zhanfen Qin (Archives of Toxicology, 2022)

Alteromonas oceanisediminis sp. nov., isolated from deep-sea sediment - Xiao-Yu Zhang; Zhen Wang; Jun-Hui Cheng; Hui-Hui Fu; Yu-Zhong Zhang; Xiu-Lan Chen; Xi-Ying Zhang; Xiao-Yan Song; Yu-Qiang Zhang; Fei Xu (Archives of Microbiology, 2022)

Pulmonary Infection Caused by Strongyloides stercoralis - Lingqing Xu; Qianjun He; Linjuan Chen; Jiaxi Lv; Yinxian Tang; Yuzhen Li; Zhongwen Zhang; Weihong Wen; Guoquan Zhong; Hui Liu; Bishi Fu (Acta Parasitologica, 2022)

Late Cambrian tonalite-trondhjemite association in the eastern segment of North Qilian suture zone: petrogenesis and geodynamic implications - Yuxiao Chen; Ying Cui; Shuguang Song; Shanming Fu; Lipeng Zhang; Weidong Sun; Tangfu Xiao (International Geology Review, 2022)

Genome-wide SNP analysis reveals the selection signatures of two indigenous buffalo breeds in Sichuan - Wei Wang; Donghui Fang; Yi Shi; Fang He; Jia Gan; Maozhong Fu; Xiaodong Deng; Tao Zhang; Hongbing Shen; Shengchao Zhong; Yueda Aguo; Luxi Chen; et al. (Conservation Genetics Resources, 2022)
Sichuan Province spawned abundant of indigenous buffalo varieties, which probably harbor valuable gene resources beneficial to the genetic improvement of buffalo. However, limited genetic information was publicly available. To better understand their selection signatures between different populations, we performed a restriction site-associated DNA sequencing (RADseq) to explore genome-wide SNPs among two indigenous breeds of Sichuan buffaloes. As a result, a total of 2,110,077 high-quality SNPs were finally obtained. Population genetic analysis indicated a obviously genetic differentiation between two breeds. The detection of selective genes showed that 995 and 910 protein-coding genes underwent positive selection in Yibin buffalo (GYBS) and Dechang buffalo (XCS). Further functional analysis revealed distinctly discrepant selection in two breeds. Candidate genes that positively selected from Yibin buffaloes have mainly occurred in functions closely related to meat quality, complex living environment adaption capability, and disease resistance. While they were significantly enriched in cell proliferation and cell components in Dechang buffalo, indicating the selection pressure primarily derived from the requirement of organism growth and development speed during breed formation. Our dataset constitutes a promising reservoir of genome-wide SNP markers of Sichuan buffaloes and provides potentially traits selected in different local populations. Such comprehensive genetic resources offer an unprecedented opportunity for genetic association analysis of economically important traits and precision breeding programs in buffaloes.

Extraction and analysis of an organophosphate salt nucleating agent from irradiated polypropylene resin - Mary Dawn Celiz; Kim M. Morehouse; Clark D. Ridge; Fu Chen; Lowri S. deJager; Timothy H. Begley (Food Additives & Contaminants: Part A, 2022)

Phenolic compounds from the sclerotia of Inonotus obliquus - Yan-Mei Wei; Li Yang; Wen-Li Mei; Hui-Qin Chen; Cai-Hong Cai; Wei Li; Wen-Hua Dong; Zhi-Bao Chen; Hao-Fu Dai (Natural Product Research, 2022)

Comparative effects of cannabinoid CB1 receptor agonist and antagonist on timing impulsivity induced by d-amphetamine in a differential reinforcement of low-rate response task in male rats - Shuo-Fu Chen; Wei-Chung Hsu; Xi-Yun Lu; Chuen-Yu Chuang; Ruey-Ming Liao (Psychopharmacology, 2022)

Predisposition to atrioventricular septal defects may be caused by SOX7 variants that impair interaction with GATA4 - Baolei Li; Zhuoyan Li; Jianping Yang; Nanchao Hong; Lihui Jin; Yuejuan Xu; Qihua Fu; Kun Sun; Yu Yu; Yanan Lu; Sun Chen (Molecular Genetics and Genomics, 2022)

Dexmedetomidine post-conditioning alleviates myocardial ischemia–reperfusion injury in rats by ferroptosis inhibition via SLC7A11/GPX4 axis activation - Peng Yu; Jing Zhang; Yi Ding; Dandan Chen; Haijian Sun; Fenglai Yuan; Siyuan Li; Xiaozhong Li; Pingping Yang; Linghua Fu; Shuchun Yu; Jiru Zhang (Human Cell, 2022)

Experimental Study on Mechanical Properties of Sandstone Under Sinusoidal Dynamic Load - Boxue Fu; Dongming Zhang; Chen Ye (Geotechnical and Geological Engineering, 2022)

Development of modified integrated water quality index to assess the surface water quality: a case study of Tuo River, China - Dong Fu; Shu Chen; Yongcan Chen; Zhenyan Yi (Environmental Monitoring and Assessment, 2022)

Rapid onset hazards, fault-controlled landslides and multi-method emergency decision-making - Fu-yun Guo; Xing-min Meng; Tian-jun Qi; Tom Dijkstra; Jarsve Kristine Thorkildsen; Dong-xia Yue; Guan Chen; Yi Zhang; Xiao-dong Dou; Peng-qing Shi (Journal of Mountain Science, 2022)

High-resolution inventory of emissions of atmospheric PM10 from agricultural tillage and harvesting operations in China: historical trend, spatio-temporality, and optimization methodology - Jing Fu; Ruimin Li; Xuewei Wu; Mengduo Zhang; Weiwei Chen; Daniel Tong (Air Quality, Atmosphere & Health, 2022)

microRNA (miR‐KT‐635) encoded by Cyprinid herpesvirus 2 regulates the viral replication with targeting to the ORF23 - Qikang Chen; Yang Luo; Yan Fu; Zizhao Feng; Liqun Lu; Yousheng Jiang; Dan Xu (Journal of Fish Diseases, 2022)
Herpesviruses have been reported to be able to encode and express functional viral microRNAs that target both viral and cellular transcripts. In our previous studies, we found a new miRNA miR‐KT‐635 encoded by Cyprinid herpesvirus 2, which is predicted to target viral genes and cellular genes involved in innate immune signalling pathway and apoptosis. However, the function and target gene of miR‐KT‐635 are not proved. In this study, the regulating target gene of miR‐KT‐635 was proved as the viral gene ORF23 directly, the target point sequence on gene was verified and miR‐KT‐635 was identified to regulate the expression of ORF23 protein. According to the bioinformatics analysis, the tRNA domain and ribosome domain in the protein sequence of ORF23 were found to share high homology with R2i and P53R2i, which are related to the ribonucleotide reductase small subunit in the host (transform NTP to dNTP). Within expectations, silencing of viral ORF23 or transfecting miR‐KT‐635 mimics in Carassius auratus gibelio caudal fin cell line (GiCF) could suppress viral propagation significantly.

Higher temperature sensitivity of flowering than leaf‐out alters the time between phenophases across temperate tree species - Xiaojun Geng; Yongshuo H. Fu; Shilong Piao; Fanghua Hao; Hans J. De Boeck; Xuan Zhang; Shouzhi Chen; Yahui Guo; Janet S. Prevéy; Yann Vitasse; Josep Peñuelas; Ivan A. Janssens; et al. (Global Ecology and Biogeography, 2022)
Aim The aims of this study were to evaluate the changes in the length of the time period between leaf‐out and flowering across temperate tree species, and associate these changes with potential physiological and environmental drivers to enhance mechanistic insight into these phenomena. Location Central Europe. Time period 1980–2016. Major taxa studied Six temperate woody species. Methods Statistical analyses were carried out based on long‐term ground observations of both spring leaf‐out and flowering across temperate tree species during 1980–2016, a period characterized by rapid warming. Results The temperature sensitivity of flowering (−5.4 ± 0.04 days/℃, mean ± SE ) was higher than that of leaf‐out (−4.6 ± 0.04 days/℃) across all species, regardless of whether leaf‐out occurred before or after flowering. This study postulates a hypothesis attributing the different temperature sensitivities to different thermal sensitivities, thermal requirements, and photoperiodic controls. Main conclusions The larger temperature sensitivity of flowering than leaf‐out resulted in an extended time period between flowering and leaf‐out in species that bloom before leafing out, but a shorter time period between these phenophases in species with the opposite strategy. We would like to emphasize the importance of changes in time period between different phenophases, and we recommend conducting experimental research to reveal the underlying mechanisms of plant phenology response to climate change, and to explore its potential ecological implications.

Demographic composition, not demographic diversity, predicts biomass and turnover across temperate and tropical forests - Jessica F. Needham; Daniel J. Johnson; Kristina J. Anderson‐Teixeira; Norman Bourg; Sarayudh Bunyavejchewin; Nathalie Butt; Min Cao; Dairon Cárdenas; Chia‐Hao Chang‐Yang; Yu‐Yun Chen; George Chuyong; Handanakere S. Dattaraja; et al. (Global Change Biology, 2022)
The growth and survival of individual trees determine the physical structure of a forest with important consequences for forest function. However, given the diversity of tree species and forest biomes, quantifying the multitude of demographic strategies within and across forests and the way that they translate into forest structure and function remains a significant challenge. Here, we quantify the demographic rates of 1961 tree species from temperate and tropical forests and evaluate how demographic diversity (DD) and demographic composition (DC) differ across forests, and how these differences in demography relate to species richness, aboveground biomass (AGB), and carbon residence time. We find wide variation in DD and DC across forest plots, patterns that are not explained by species richness or climate variables alone. There is no evidence that DD has an effect on either AGB or carbon residence time. Rather, the DC of forests, specifically the relative abundance of large statured species, predicted both biomass and carbon residence time. Our results demonstrate the distinct DCs of globally distributed forests, reflecting biogeography, recent history, and current plot conditions. Linking the DC of forests to resilience or vulnerability to climate change, will improve the precision and accuracy of predictions of future forest composition, structure, and function.

A new picrotoxane-type sesquiterpene from Dendrobium nobile Lindl - Pei Wang; Xin Chen; Cai-Hong Cai; Fan-Dong Kong; Sheng-Zhuo Huang; Jing-Zhe Yuan; Xing-Lian Xu; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2022)

Application of cyclodextrin in food industry - Yang Liu; Yanna Chen; Xingli Gao; Jijun Fu; Liandong Hu (Critical Reviews in Food Science and Nutrition, 2022)

Experimental Investigation and Semi-Analytical Simulation of Instantaneous and Time-Dependent Damage Behaviors of Beishan Granite - Qiao-Juan Yu; Qi-Zhi Zhu; Liang Chen; Jian-Fu Shao (Rock Mechanics and Rock Engineering, 2022)

Characterization of Coal Structure of High-Thickness Coal Reservoir Using Geophysical Logging: A Case Study in Southern Junggar Basin, Xinjiang, Northwest China - Junqiang Kang; Xuehai Fu; Jian Shen; Shun Liang; Hao Chen; Fuhua Shang (Natural Resources Research, 2022)

Water adsorption characteristic and its impact on pore structure and methane adsorption of various rank coals - Ming-yi Chen; Xiao-yun Chen; Liang Wang; Fu-chao Tian; Yu-meng Yang; Xue-jie Zhang; Ya-pu Yang (Environmental Science and Pollution Research, 2022)

Humic Acid and Iron Chelation Modified Anode Improves the Electrochemical Performance of Marine Sediment Microbial Fuel Cell - Yubin Fu; Jiaqi Chen; Yan Chen; Xiang Huang; Yang Li; Huaijing Zhang; Xuerong Zai (Journal of Ocean University of China, 2022)

Ribosomal ITS sequence-directed selection for endophytic Myrothecium strains antagonistic to Ralstonia solanacearum to control patchouli bacterial wilt - Wenguang Shi; Jiaqi Li; Huaxiong Yao; Jianbin Li; Meiqi Chen; Danting Chen; Yinghao Fu; Huarong Xie; Zujun Deng (BioControl, 2022)

Empty-hole effect on fracture propagation under blasting load - Yanxin Lv; Chao Yuan; Yanzhao Fu; Xiaohua Zhu; Quan Gan; Haibo Li; Qiuyu Chen (Arabian Journal of Geosciences, 2022)

Enhanced Intramuscular Bioavailability of Cannabidiol Using Nanocrystals: Formulation, In Vitro Appraisal, and Pharmacokinetics - Xinzhen Fu; Shiji Xu; Zhi Li; Kun Chen; Huaying Fan; Yu Wang; Zeping Xie; Lijuan Kou; Shumin Zhang (AAPS PharmSciTech, 2022)

Six phenanthrenes from the roots of Cymbidium faberi Rolfe. and their biological activities - Shuang-shuang Lv; Yu Fu; Jun Chen; Yuan Jiao; Sui-qing Chen (Natural Product Research, 2022)

Influence of initial water content and strain rate on remolded yield stress in marine clay - Xiaobing Li; Jianpeng Chen; Xiuqing Hu; Hongtao Fu; Jun Wang; Xueyu Geng (Marine Georesources & Geotechnology, 2022)

The Anthurium APRR2-like Gene Promotes Photosynthetic Pigment Accumulation in Response to Salt Stress - Li Jiang; Yanxia Fu; Xingkai Tian; Yuehua Ma; Fadi Chen; Guangdong Wang (Tropical Plant Biology, 2022)

Fine-mapping and identification of a candidate gene controlling seed coat color in melon (Cucumis melo L. var. chinensis Pangalo) - Zhicheng Hu; Xueyin Shi; Xuemiao Chen; Jing Zheng; Aiai Zhang; Huaisong Wang; Qiushi Fu (Theoretical and Applied Genetics, 2022)

Neural circuit control of innate behaviors - Wei Xiao; Zhuo-Lei Jiao; Esra Senol; Jiwei Yao; Miao Zhao; Zheng-Dong Zhao; Xiaowei Chen; Peng Cao; Yu Fu; Zhihua Gao; Wei L. Shen; Xiao-Hong Xu (Science China Life Sciences, 2022)

Long Non-coding Antisense RNA DDIT4-AS1 Regulates Meningitic Escherichia coli-Induced Neuroinflammation by Promoting DDIT4 mRNA Stability - Bo Yang; Bojie Xu; Ruicheng Yang; Jiyang Fu; Liang Li; Dong Huo; Jiaqi Chen; Xiaopei Yang; Chen Tan; Huanchun Chen; Xiangru Wang (Molecular Neurobiology, 2022)
Our previous studies have shown that meningitic Escherichia coli can colonize the brain and cause neuroinflammation. Controlling the balance of inflammatory responses in the host central nervous system is particularly vital. Emerging evidence has shown the important regulatory roles of long non-coding RNAs (lncRNAs) in a wide range of biological and pathological processes. However, whether lncRNAs participate in the regulation of meningitic E. coli -mediated neuroinflammation remains unknown. In the present study, we characterized a cytoplasm-enriched antisense lncRNA DDIT4-AS1 , which showed similar concordant expression patterns with its parental mRNA DDIT4 upon E. coli infection. DDIT4-AS1 modulated DDIT4 expression at both mRNA and protein levels. Mechanistically, DDIT4-AS1 promoted the stability of DDIT4 mRNA through RNA duplex formation. DDIT4-AS1 knockdown and DDIT4 knockout both attenuated E. coli -induced NF-κB signaling as well as pro-inflammatory cytokines expression, and DDIT4-AS1 regulated the inflammatory response by targeting DDIT4 . In summary, our results show that DDIT4-AS1 promotes E. coli -induced neuroinflammatory responses by enhancing the stability of DDIT4 mRNA through RNA duplex formation, providing potential nucleic acid targets for new therapeutic interventions in the treatment of bacterial meningitis.

LncRNA PVT1 facilitates DLBCL development via miR-34b-5p/Foxp1 pathway - Shi Tao; Yu Chen; Min Hu; Lu Xu; Cai-Bo Fu; Xin-Bao Hao (Molecular and Cellular Biochemistry, 2022)

Reliability Analysis of Reinforced Slope Combining Random Forest Algorithm and Meshless SPH Algorithm - Xu Liu; Liang Li; ShangShang Wang; Fu Chen; Ming Zhai; Zhengquan Yang; Yuan Gao (Geotechnical and Geological Engineering, 2022)

The effect of preoperative statin treatment on acute kidney injury in elderly patients undergoing valve replacement surgery - Bing-qi Fu; Xue-biao Wei; Zedazhong Su; Ying-wen Lin; Zu-hui Ke; Tong Tan; Ji-yan Chen; Shou-hong Wang; Dan-qing Yu (European Journal of Clinical Pharmacology, 2022)

The failure mode of transmission tower foundation on the landslide under heavy rainfall: a case study on a 500-kV transmission tower foundation on the Yanzi landslide in Badong, China - Yongqiang Zhou; Qian Sheng; Jian Chen; Nana Li; Xiaodong Fu; Yingbo Zhou (Bulletin of Engineering Geology and the Environment, 2022)

A highly pathogenic Marek’s disease virus isolate from chickens immunized with a bivalent vaccine in China - Huimin Li; Zengxu Ge; Qiong Luo; Qiang Fu; Ruiai Chen (Archives of Virology, 2022)

Comparative evaluation of energy consumption and emissions in the life cycle of extended-range and battery electric vehicles - Yisong Chen; Yang Yang; Yunxiang Xing; Ying Cao; Haibo Xu; Pei Fu (Arabian Journal of Geosciences, 2022)

Using data-limited approaches to assess data-rich Indian Ocean bigeye tuna: Data quantity evaluation and critical information for management implications - Ya’nan Li; Jiangfeng Zhu; Xiaojie Dai; Dan Fu; Yong Chen (Acta Oceanologica Sinica, 2022)

A multi-stage supply chain disruption mitigation strategy considering product life cycle during COVID-19 - Jingze Chen; Hongfeng Wang; Yaping Fu (Environmental Science and Pollution Research, 2022)

Combined Effects of Microplastics and Benzo[a]pyrene on the Marine Diatom Chaetoceros muelleri - Yuanyuan Su; Huaiyuan Qi; Yipeng Hou; Mengyi Gao; Jie Li; Minggang Cai; Xiaoshan Zhu; Miao Chen; Chengjun Ge; Dongdong Fu; Zezheng Wang; Licheng Peng (Frontiers in Marine Science, 2022)
Microplastics are regarded as ubiquitous pollutants in the ocean and have attracted worldwide concerns. Benzo[a]pyrene (B[a]P), one of typical polycyclic aromatic hydrocarbons (PAHs), is commonly detected in marine environment. Once coexisted, the microplastics and B[a]P may interact with each other and result in combined toxicity to organisms, and these remain to be systematically elucidated. Thus, this study aims to investigate (i) the effects of single micro-sized polystyrene (mPS), polyethylene terephthalate (mPET), and B[a]P on cell growth of Chaetoceros muelleri ; and (ii) the interaction of microplastics and B[a]P, and their combined effects on C. muelleri . The results showed that both single microplastics and B[a]P at a high concentration of 150 μg/L inhibited the growth of C. muelleri . For single treatment of microplastics, stronger inhibition effects on microalgae was caused by mPET than that of mPS, with the highest IR of 25.23 and 11.17%, respectively. This may be attributed to the obvious surface roughness of mPET. By comparison, the combined effects of microplastics and B[a]P significantly inhibited the growth of C. muelleri as compared with the single treatment of B[a]P ( P < 0.05). Synergistic effect was found in the combination of microplastics with B[a]P at high concentrations of 150 μg/L. Interestingly, the antagonistic effect on C. muelleri was observed in the combined treatment of microplastics and B[a]P at low concentrations of 10 μg/L. In addition, the pollutants reduced the content of photosynthetic pigments in microalgal cells. The SOD and MDA content of microalgae increased in the early stage of exposure to pollutants (e.g., Days 1 and 5), but decreased in the later stage (Day 15) compared with the control group. The decreased superoxide dismutase (SOD) and catalase (CAT) activity in single and composite systems may indicate that the antioxidative enzymatic system of microalgae has been inhibited or destroyed. This study will be helpful to further explore the ecological threats of microplastics and PAHs to the marine ecosystem.

Neutrophil Extracellular Traps may be a Potential Target for Treating Early Brain Injury in Subarachnoid Hemorrhage - Hanhai Zeng; Xiongjie Fu; Jing Cai; Chenjun Sun; Mengyan Yu; Yucong Peng; Jianfeng Zhuang; Jingyin Chen; Huaijun Chen; Qian Yu; Chaoran Xu; Hang Zhou; et al. (Translational Stroke Research, 2022)

A Neural Circuit Mechanism Controlling Breathing by Leptin in the Nucleus Tractus Solitarii - Hongxiao Yu; Luo Shi; Jinting Chen; Shirui Jun; Yinchao Hao; Shuang Wang; Congrui Fu; Xiang Zhang; Haiyan Lu; Sheng Wang; Fang Yuan (Neuroscience Bulletin, 2022)

Comparative Transcriptome Analysis of Spleen Reveals Potential Regulation of Genes and Immune Pathways Following Administration of Aeromonas salmonicida subsp. masoucida Vaccine in Atlantic Salmon (Salmo salar) - Qiang Fu; Yuqing Li; Hao Zhang; Min Cao; Lu Zhang; Chengbin Gao; Xin Cai; Defeng Chen; Ziying Yang; Jie Li; Ning Yang; Chao Li (Marine Biotechnology, 2022)

Phactr1 negatively regulates bone mass by inhibiting osteogenesis and promoting adipogenesis of BMSCs via RhoA/ROCK2 - Wei Lin; Zhipeng Chen; Xiaoyi Mo; Shengli Zhao; Zhenxing Wen; Wing Hoi Cheung; Dan Fu; Bailing Chen (Journal of Molecular Histology, 2022)

Effect of gene polymorphism on bleeding complications in Chinese Han patients taking warfarin - Xiaotong Xia; Jinglan Fu; Tingting Wu; Wenjun Chen; Shaojun Jiang; Meina Lv; Jinhua Zhang (European Journal of Clinical Pharmacology, 2022)

A study on the contamination assessment, health risk and mobility of two heavy metals in the soil-plants-ruminants system of a typical agricultural region in the semi arid environment - Xiaoping Ge; Zafar Iqbal Khan; Fu Chen; Mubeen Akhtar; Kafeel Ahmad; Abid Ejaz; Muhammad Arslan Ashraf; Muhammad Nadeem; Shahzad Akhtar; Jawaher Alkahtani; Yheni Dwiningsih; Mohamed S. Elshikh (Environmental Science and Pollution Research, 2022)

Decomposition and decoupling research of Chinese power sector carbon emissions through the consumption accounting principle - Keliang Chang; Guijing Chen; Zifang Du; Fujun Hou; Jiaqi Li; Fu Chen (Environmental Science and Pollution Research, 2022)

Airborne black carbon variations during the COVID-19 lockdown in the Yangtze River Delta megacities suggest actions to curb global warming - Hao Li; Kan Huang; Qingyan Fu; Yanfen Lin; Jia Chen; Congrui Deng; Xudong Tian; Qian Tang; Qingchuan Song; Zhen Wei (Environmental Chemistry Letters, 2022)

Yohimbine Directly Induces Cardiotoxicity on Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes - Yiqi Gong; Li Yang; Jun Tang; Jijian Zheng; Nevin Witman; Philipp Jakob; Yao Tan; Minglu Liu; Ying Chen; Huijing Wang; Wei Fu; Wei Wang (Cardiovascular Toxicology, 2022)

Different effects of the DRD4 genotype on intrinsic brain network connectivity strength in drug-naïve children with ADHD and healthy controls - Shuangli Chen; Andan Qian; Jiejie Tao; Ronghui Zhou; Chuqi Fu; Chuang Yang; Qingxia Lin; JieJie Zhou; Jiance Li; Xiaoqi Huang; Meihao Wang (Brain Imaging and Behavior, 2022)
The dopamine D4 receptor gene (DRD4) has been consistently reported to be associated with attention-deficit/hyperactivity disorder (ADHD). Recent studies have linked DRD4 to functional connectivity among specific brain regions. The current study aimed to compare the effects of the DRD4 genotype on functional integrity in drug-naïve ADHD children and healthy children. Resting-state functional MRI images were acquired from 49 children with ADHD and 37 healthy controls (HCs). We investigated the effects of the 2-repeat allele of DRD4 on brain network connectivity in both groups using a parameter called the degree of centrality (DC), which indexes local functional relationships across the entire brain connectome. A voxel-wise two-way ANCOVA was performed to examine the diagnosis-by-genotype interactions on DC maps. Significant diagnosis-by-genotype interactions with DC were found in the temporal lobe, including the left inferior temporal gyrus (ITG) and bilateral middle temporal gyrus (MTG) (GRF corrected at voxel level p < 0.001 and cluster level p < 0.05, two-tailed). With the further subdivision of the DC network according to anatomical distance, additional brain regions with significant interactions were found in the long-range DC network, including the left superior parietal gyrus (SPG) and right middle frontal gyrus (MFG). The post-hoc pairwise analysis found that altered network centrality related to DRD4 differed according to diagnostic status (p < 0.05). This genetic imaging study suggests that the DRD4 genotype regulates the functional integration of brain networks in children with ADHD and HCs differently. This may have important implications for our understanding of the role of DRD4 in altering functional connectivity in ADHD subjects.

The impact of different rotation regime on the soil bacterial and fungal communities in an intensively managed agricultural region - Jie Lu; Wenxin Li; Yuhao Yang; Fan Ye; Huayu Lu; Xiangyang Chen; Fu Chen; Xinya Wen (Archives of Microbiology, 2022)

Analysis of factors affecting the reservoir quality of deepwater gravity flow tight sandstone: a case study of the Chang 6 oil reservoir of the Yanchang Formation in the Huaqing area, China - Zhaobing Chen; Ling Fu; Chuangfei Zhou; Jianrong Gao; Xinshe Liu; Xinjing Chen; Yushuang Zhu; Yuhang Chen (Arabian Journal of Geosciences, 2022)

Development and validation of a 30-day death nomogram in patients with spontaneous cerebral hemorrhage: a retrospective cohort study - Qian Han; Mei Li; Dongpo Su; Aijun Fu; Lin Li; Tong Chen (Acta Neurologica Belgica, 2022)

Identification and Characterization of Immunoglobulin T Heavy Chain in Large Yellow Croaker (Larimichthys crocea) - Yan Teng; Qiuling Fu; Yuanzhen Tan; Yangyang Ding; Yang Ding; Xinhua Chen (Fishes, 2022)
Three immunoglobulin (Ig) isotypes have been identified in teleosts, IgM, IgD, and IgT or IgZ. IgT, a new teleost Ig isotype, plays a vital role in mucosal immunity. However, information on molecular and functional characteristics of fish IgT is still limited. In this study, an IgT heavy chain (LcIgT) gene was cloned and characterized in large yellow croaker (Larimichthys crocea). Complete cDNA of LcIgT was 1930 bp in length, encoding a protein of 554 amino acids. The deduced LcIgT contains a VH region and only three CH regions (CH1, CH2, CH4), but no transmembrane region was predicted. Phylogenetic analysis showed that IgT heavy chain sequences from all fish species are grouped together. Homology comparison showed that LcIgT shares the highest amino acid identity of 58.73% with IgT heavy chain in Scophthalmus maximus. The VH domain of LcIgT has the highest identity of 72.50% with that of Scophthalmus maximus IgT. Relatively, each constant domain of LcIgT exhibits the highest amino acid identity with that of IgT in Oreochromis niloticus (67.61% identity for CH1, 61.11% identity for CH2, and 63.74% identity for CH4). LcIgT was constitutively expressed in various tissues tested, with the highest levels in mucosa-associated tissues such as gills and skin. After Cryptocaryon irritans infection, the mRNA levels of LcIgT were significantly up-regulated in the spleen (3.27-fold) at 4 d, in the head kidney (3.98-fold) and skin (2.11-fold) at 7 d, and in gills (4.45-fold) at 14 d. The protein levels in these detected tissues were all significantly up-regulated; the peak of its up-regulation was 6.33-fold at 28d in gills, 3.44-fold at 7d in skin, and 3.72-fold at 14d in spleen. These results showed that IgT response could be simultaneously induced in both systemic and mucosal tissues after parasitic infection and that IgT may be involved in systemic immunity and mucosal immunity against parasitic infection.

Physical Responses of Pinctada fucata to Salinity Stress - Jingru Yang; Jinling Yang; Mingqiang Chen; Zhengyi Fu; Jing Sun; Gang Yu; Aimin Wang; Zhenhua Ma; Zhifeng Gu (Frontiers in Marine Science, 2022)
This study was conducted to understand the changes of physiological and biochemical indexes of black and red shell Pinctada fucata under acute high and low salt stress. In this study, the salinity of 35‰ was used as the control, while the salinities of 20 and 50% salinity were used as the low and high salt treatment groups, respectively. The osmotic pressure (OSM) and ion concentration in the hemolymph, Na + -K + -ATPase (NKA) activity and respiratory metabolism in gills, and antioxidant and immune (non) enzymes in the hepatopancreas of P. fucata with two shell colors were compared and analyzed at the time periods of 1.5 and 3 h post-salinity stress. The results showed that the OSM and inorganic ion (Na + , Ca 2+ , and Cl – ) concentration in the hemolymph of the black and red P. fucata increased significantly with the increase of salinity after the time periods of 1.5 and 3 h. At 3 h, the black P. fucata NKA activity decreased significantly with the increase of salinity, while red P. fucata reached the highest value at high salinity. The succinate dehydrogenase (SDH) and lactate dehydrogenase (LDH) activities of red P. fucata showed U-shaped and inverted U-shaped distributions with the increase of salinity after 1.5 h, respectively. With the increase of salinity, the phenoloxidase (POX) activity of red and black P. fucata showed inverted U-shaped and U-shaped distributions, respectively. The contents of glutathione (GSH) and vitamin C (VC) in black P. fucata decreased significantly with the increase of salinity at 1.5 and 3 h. Red P. fucata GSH and VC reached their maximum value in the 1.5-h low salinity group and 3-h high salinity group. The vitamin E (VE) content in black P. fucata increased significantly with the increase of salinity at 1.5 h, and reached the maximum at 3 h in the control group. Red P. fucata VE reached the maximum at 1.5 and 3 h in the control group. The results obtained from the present study revealed that the sensitivity of P. fucata to salinity varied in shell color. Compared to black P. fucata , red P. fucata responds more quickly to sharp salinity changes, thereby reducing more likely damage. Compared with a high salt environment, P. fucata was more adaptable to the changes of acute low salt environment. The results obtained from the present study provide the physical references for subsequent selective breeding of this species.

New paraconic acids from the endophytic fungus Xylariaceae sp. J4 - Chao Yuan; Xue-Chun Shu; Lin Fan; Ying-Bo Zhang; Ling-Liang Guan; Fu-Lai Yu; Xiao-Lu Chen; Gang Li (Natural Product Research, 2022)

Chemical composition and anti-hepatoma effect of Annona squamosa L. pericarp oil - Ya-Yun Chen; Fu-Qiang Li; Xiao-Li Zhu; Jian-Wei Chen; Xiang Li (Natural Product Research, 2022)

Enhancing the production of physiologically active vitamin D3 by engineering the hydroxylase CYP105A1 and the electron transport chain - Bing Fu; Qian Ren; Jian Ma; Qingwei Chen; Qili Zhang; Ping Yu (World Journal of Microbiology and Biotechnology, 2022)

Assembly of rhizosphere microbial communities in Artemisia annua: recruitment of plant growth‐promoting microorganisms and inter‐kingdom interactions between bacteria and fungi - Yuhua Shi; Yanshuo Pan; Li Xiang; Zhihui Zhu; Wenbo Fu; Guangfei Hao; Zengchao Geng; Shilin Chen; Yuzhong Li; Dongfei Han (Plant and Soil, 2022)

A simulation study on risks of pedestrian evacuation from flooded staircases of different slopes in the underground space - Jingming Hou; Guangzhao Chen; Yangwei Zhang; Bingyao Li; Shaoxiong Yang; Yu Tong; Dawei Zhang; Deyu Fu (Natural Hazards, 2022)

A community effort to assess and improve computerized interpretation of 12-lead resting electrocardiogram - Zijian Ding; Guijin Wang; Huazhong Yang; Ping Zhang; Dapeng Fu; Zhen Yang; Xinkang Wang; Xia Wang; Zhourui Xia; Chiming Zhang; Wenjie Cai; Binhang Yuan; et al. (Medical & Biological Engineering & Computing, 2022)
Computerized interpretation of electrocardiogram plays an important role in daily cardiovascular healthcare. However, inaccurate interpretations lead to misdiagnoses and delay proper treatments. In this work, we built a high-quality Chinese 12-lead resting electrocardiogram dataset with 15,357 records, and called for a community effort to improve the performances of CIE through the China ECG AI Contest 2019. This dataset covers most types of ECG interpretations, including the normal type, 8 common abnormal types, and the other type which includes both uncommon abnormal and noise signals. Based on the Contest, we systematically assessed and analyzed a set of top-performing methods, most of which are deep neural networks, with both their commonalities and characteristics. This study establishes the benchmarks for computerized interpretation of 12-lead resting electrocardiogram and provides insights for the development of new methods.

New monoterpenoids from the stigmas of Crocus sativus - Qing-Wei Fang; Wen-Wei Fu; Jin-Ling Yang; Yue Lu; Jiang-Cheng Chen; Pei-Ying Wu; Xue Zhang; Hong-Xi Xu (Journal of Natural Medicines, 2022)

To establish a model for the prediction of initial standard and maintenance doses of warfarin for the Han Chinese population based on gene polymorphism: a multicenter study - Xiaotong Xia; Nianxu Huang; Boxia Li; Yan Li; Lang Zou; Dongdong Yuan; Banghua Huang; Yufei Bei; Yuxin Liu; Jinglan Fu; Tingting Wu; Wenjun Chen; et al. (European Journal of Clinical Pharmacology, 2022)

Contract farming, social trust, and cleaner production behavior: field evidence from broiler farmers in China - Hui Mao; Yong Fu; Guangqiao Cao; Shaojian Chen (Environmental Science and Pollution Research, 2022)

Ecological risk assessment of heavy metal chromium in a contaminated pastureland area in the Central Punjab, Pakistan: soils vs plants vs ruminants - Fu Chen; Fatima Ghulam Muhammad; Zafar Iqbal Khan; Kafeel Ahmad; Muhammad Nadeem; Shahid Mahmood; Muhammad Umar Farooq Awan; Mudasra Munir; Ifra Saleem Malik; Asma Ashfaq; Razia Sultana; Ayesha Maqsood; et al. (Environmental Science and Pollution Research, 2022)

Evaluation of potential ecological risk and prediction of zinc accumulation and its transfer in soil plants and ruminants: public health implications - Fu Chen; Laraib Saqlain; Jing Ma; Zafar Iqbal Khan; Kafeel Ahmad; Asma Ashfaq; Razia Sultana; Fatima Ghulam Muhammad; Ayesha Maqsood; Majida Naeem; Ifra Saleem Malik; Mudasra Munir; et al. (Environmental Science and Pollution Research, 2022)

Bioaccumulation and transfer of zinc in soil plant and animal system: a health risk assessment for the grazing animals - Fu Chen; Fatima Ghulam Muhammad; Zafar Iqbal Khan; Kafeel Ahmad; Ifra Saleem Malik; Asma Ashfaq; Majida Naeem; Muhammad Nadeem; Jing Ma; Muhammad Umer Farooq Awan; Shahzadi Mahpara; Shahid Mehmood (Environmental Science and Pollution Research, 2022)

Characteristics of fine particulate matter (PM2.5) at Jinsha Site Museum, Chengdu, China - Jialin Deng; Luman Jiang; Wenwen Miao; Junke Zhang; Guiming Dong; Ke Liu; Juncheng Chen; Tong Peng; Yao Fu; Yunpei Zhou; Xue Huang; Mengqian Hu; et al. (Environmental Science and Pollution Research, 2022)

Bottomside ionospheric snapshot modeling using the LEO navigation augmentation signal from the Luojia-1A satellite - Tao Li; Lei Wang; Wenju Fu; Yi Han; Haitao Zhou; Ruizhi Chen (GPS Solutions, 2022)

Identification of bacterial blight resistance genes in rice landraces from Yunnan Province, China - Caimei Zhao; Fuyou Yin; Ling Chen; Dingqin Li; Suqin Xiao; Qiaofang Zhong; Bo Wang; Xue Ke; Jian Fu; Xiang Li; Yue Chen; Lingxian Wang; et al. (Australasian Plant Pathology, 2022)
Bacterial blight (BB), a serious bacterial disease caused by pathogen Xanthomonas oryzae pv. oryzae ( Xoo ) affects rice growth and yield. Yunnan Province is regarded as a center of rice diversity in China and indeed the world, and has abundant rice landrace resources, which may offer prospective candidate donors in rice improvement and breeding. In this study, a set of 200 rice landraces were evaluated to determine their resistance to 10 pathogenic Xoo strains resistance by the leaf-clipping method. The results indicated that the tested rice landraces had different resistance levels against different Xoo strains. Multiple comparisons showed that the Xoo strain PXO99 was virulent to the tested rice landraces. Sixty-six rice landraces conferred resistance against at least one Xoo strain. These resistant rice landraces screened were then performed the presence of 14 cloned BB resistance genes by closely linked molecular markers and designed specific primers. The results showed that none of these resistant accessions contained xa13 , Xa21 , Xa27 , and Xa45(t) homologous fragments, while 9, 24, 4, 7, 9, 15, 1, 5, 4 and 27 accessions contained Xa1 , Xa2/Xa31(t) , Xa14 , Xa3/Xa26 , Xa4 , xa5 , Xa7 , Xa10 , Xa23 and xa25 homologous fragments, respectively. Sequence analysis further revealed that nucleotide variations around functional nucleotide polymorphisms region were observed within these accessions containing the Xa1 , Xa2/Xa31(t) , Xa14 , Xa3/Xa26 , Xa4 , xa5 , Xa10 , Xa23 and xa25 homologous fragments. These results along with phenotypic resistance spectrum supported that these accessions carried nine resistance homologous genes. Only one accession (Qishanggu_Wenshan) carried the Xa7 resistance gene. We also found that some resistant rice landraces, especially Xilandigu_Baoshan, and Laoyaling_Lincang without the above resistance genes, which mediated broad spectrum resistance to multiple Xoo strains, were identified as potential sources for breeding rice lines resistance to BB.

A novel alphahypovirus that infects the fungal plant pathogen Sclerotinia sclerotiorum - Weibo Liang; Zhongbo Lu; Jie Duan; Daohong Jiang; Jiatao Xie; Jiasen Cheng; Yanping Fu; Tao Chen; Bo Li; Xiao Yu; Weidong Chen; Yang Lin (Archives of Virology, 2022)

Geochemical characteristics and source of crude oil in the Shenhu uplift, Pearl River Mouth Basin, South China Sea - Xiaoyan Fu; Shijia Chen; Xin He; Junjun You; Hui Li; Mingzhu Lei (Arabian Journal of Geosciences, 2022)

Identification of the vertical sealing of faults by geochemical methods—taking the Zhu-3 sub-basin of the Pearl River Mouth Basin as an example - Xiaoyan Fu; Shijia Chen; Junjun You; Hui Li; Mingzhu Lei (Arabian Journal of Geosciences, 2022)

Not out of the woods yet: Signatures of the prolonged negative genetic consequences of a population bottleneck in a rapidly re‐expanding wader, the black‐faced spoonbill Platalea minor - Shou‐Hsien Li; Yang Liu; Chia‐Fen Yeh; Yuchen Fu; Carol K. L. Yeung; Chun‐Cheng Lee; Chi‐Cheng Chiu; Tung Hui Kuo; Fang‐Tse Chan; Yu‐Chia Chen; Wen‐Ya Ko; Cheng‐Te Yao (Molecular Ecology, 2022)
The long‐term persistence of a population which has suffered a bottleneck partly depends on how historical demographic dynamics impacted its genetic diversity and the accumulation of deleterious mutations. Here we provide genomic evidence for the genetic effect of a recent population bottleneck in the endangered black‐faced spoonbill ( Platalea minor ) after its rapid population recovery. Our data suggest that the bird's effective population size, N e , had been relatively stable (7500–9000) since 22,000 years ago; however, a recent brief yet severe bottleneck ( N e = 20) which we here estimated to occur around the 1940s wiped out >99% of its historical N e in roughly three generations. Despite a >15‐fold population recovery since 1988, we found that black‐faced spoonbill population has higher levels of inbreeding (7.4 times more runs of homozygosity) than its sister species, the royal spoonbill ( P. regia ), which is not thought to have undergone a marked population contraction. Although the two spoonbills have similar levels of genome‐wide genetic diversity, our results suggest that selection on more genes was relaxed in the black‐faced spoonbill; moreover individual black‐faced spoonbills carry more putatively deleterious mutations (Grantham's score > 50), and may therefore express more deleterious phenotypic effects than royal spoonbills. Here we demonstrate the value of using genomic indices to monitor levels of genetic erosion, inbreeding and mutation load in species with conservation concerns. To mitigate the prolonged negative genetic effect of a population bottleneck, we recommend that all possible measures should be employed to maintain population growth of a threatened species.

Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level - Qi‐Long Qin; Zhi‐Bin Wang; Qian‐Qian Cha; Sha‐Sha Liu; Xue‐Bing Ren; Hui‐Hui Fu; Mei‐Ling Sun; Dian‐Li Zhao; Andrew McMinn; Yin Chen; Xiu‐Lan Chen; Yu‐Zhong Zhang; et al. (Environmental Microbiology, 2022)
Summary Based on 16S rRNA gene analyses, the same bacterial operational taxonomic units (OTUs) are common to both the Arctic and Antarctic oceans, supporting the concept ‘everything is everywhere’. However, whether the same OTUs from both poles have identical genomes, i.e. whether ‘everything is still everywhere’ at the genomic level has not yet been examined systematically. Here, we isolated, sequenced and compared the genomes of 45 culturable marine bacteria belonging to three genera of Salinibacterium , Psychrobacter and Pseudoalteromonas from both polar oceans. The bacterial strains with identical 16S rRNA genes were common to both poles in every genus, and four identical genomes were detected in the genus Salinibacterium from the Arctic region. However, no identical genomes were observed from opposite poles in this study. Our data, therefore, suggest that ‘everything is not everywhere’ at the genomic level. The divergence time between bacteria is hypothesized to exert a strong impact on the bacterial biogeography at the genomic level. The geographical isolation between poles was observed for recently diverged, highly similar genomes, but not for moderately similar genomes. This study thus improves our understanding of the factors affecting the genomic‐level biogeography of marine microorganisms isolated from distant locations.

Interactive Regulations of Dynamic Methylation and Transcriptional Responses to Recurring Environmental Stresses During Biological Invasions - Ruiying Fu; Xuena Huang; Yiyong Chen; Zaohuang Chen; Aibin Zhan (Frontiers in Marine Science, 2021)
Deoxyribonucleic acid methylation and gene transcription have been proved as two underlying mechanisms involved in rapid plastic response to environmental stresses. However, it remains elusive on how DNA methylation regulates gene transcription under acute and recurring environmental challenges to form the stress memory, further contributing to invasion success during range expansions. Using a model invasive species Ciona robusta , we investigated the regulatory roles of DNA methylation on gene transcription and their contribution to the formation of stress memory at 30 genes under acute and recurring osmotic challenges simulated during the invasion process. We found the bimodal distribution of methylation level for the 68 mCpGs identified across all the genes after challenges, but only five sites were significantly correlated with the expression of their corresponding genes. These genes participated in the biological processes of Ca 2+ transport and metabolism of lipid and proline. At the DNA methylation level, we found two early-responding and four tardy-responding sites of stress memory and these sites were functionally related to genes involved in the biosynthesis of proline, metabolism of lipid, and transport of taurine and Ca 2+ . At the transcriptional level, three tardy-responding and five early-responding memory genes were involved in the transport of ions, regulation of water channels, biosynthesis of taurine, and metabolism of lipid. Altogether, the findings here suggest that DNA methylation and gene transcription should work in concert to facilitate the formation of stress memory, thus further improving the performance of invaders under recurring environmental challenges during biological invasions.

Ferroptosis inhibitory constituents from the fruits of Cullen corylifolium - Aftab Yaseen; Fan Yang; Xia Zhang; Fu Li; Bin Chen; Ahmed Hassan Ibrahim Faraag; Ming-Kui Wang; Xiao-Fei Shen; Lun Wang (Natural Product Research, 2021)

Adsorption of BDE-209 to Polyethylene Microplastics: Effect of Microplastics Property and Metal Ions - Yanfeng Zhu; Xiaoxiao Li; Liping Wang; Nan Hui; Jing Ma; Fu Chen (Water, Air, & Soil Pollution, 2021)

Changes of Community Structure and Functional Feeding Groups of Benthic Macrofauna After Mangrove Afforestation in a Subtropical Intertidal Zone, China - Yiyong Rao; Lizhe Cai; Xiping Zhou; Sujing Fu; Wenqing Peng; Xinwei Chen; Bin Zheng (Wetlands, 2021)

Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice - Xiongjie Fu; Hanhai Zeng; Jikuang Zhao; Guoyang Zhou; Hang Zhou; Jianfeng Zhuang; Chaoran Xu; Jianru Li; Yucong Peng; Yang Cao; Yin Li; Huaijun Chen; et al. (Translational Stroke Research, 2021)

Recent advances in tissue stem cells - Xin Fu; Qiang He; Yu Tao; Mengdi Wang; Wei Wang; Yalong Wang; Qing Cissy Yu; Fang Zhang; Xiaoyu Zhang; Ye-Guang Chen; Dong Gao; Ping Hu; et al. (Science China Life Sciences, 2021)

Identification of key gene networks controlling vernalization development characteristics of Isatis indigotica by full-length transcriptomes and gene expression profiles - Pan Wang; Dong Liu; Fu-Hong Yang; Hui Ge; Xin Zhao; Hong-Gang Chen; Tao Du (Physiology and Molecular Biology of Plants, 2021)
Isatis indigotica Fort . , as a common Chinese medicinal raw material, will lose its medicinal value if it blooms early, so it is highly valuable to clarify the induction mechanism of the vernalization of I. indigotica at low temperature. In this study, the concentrations of soluble sugar, proline, glutathione and zeatin in two germplasms of I. indigotica with different degrees of low temperature tolerance (Y1 and Y2) were determined at 10 days, 20 days and 30 days of low-temperature treatment, and the full-length transcriptome of 24 samples was sequenced by Nanopore sequencing with Oxford Nanopore Technologies (ONT). After that, the data of transcripts involved in the vernalization of I. indigotica at low temperature were obtained, and these transcripts were identified using weighted gene co-expression network analysis (WGCNA). The results revealed the massive accumulation of soluble sugar and proline in Y1 and Y2 after low temperature induction. A total of 18,385 new transcripts, 6168 transcription factors and 470 lncRNAs were obtained. Differential expression analysis showed that gibberellin, flavonoids, fatty acids and some processes related to low temperature response were significantly enriched. Eight key transcripts were identified by WGCNA, among which ONT.14640.1, ONT.9119.1, ONT.13080.2 and ONT.16007.1 encodes a flavonoid transporter, 9-cis-epoxycarotenoid dioxygenase 3 (NCED3), growth factor gene and L-aspartate oxidase in plants, respectively . It indicated that secondary metabolites such as hormones and flavonoids play an important role in the vernalization of I. indigotica . qRT-PCR proved the reliability of transcriptome results. These results provide important insights on the low-temperature vernalization of I. indigotica , and provide a research basis for analyzing the vernalization mechanism of I. indigotica .

A comparison of atmospheric geochemistry through lichens from volcanic and non-volcanic areas, north Taiwan - Le-Qi Lin; Hsueh-Yu Lu; Ju-Lien Pi; Tai-Sheng Liou; Wen-Fu Chen; Pei-Shan Hsieh (Journal of Earth System Science, 2021)

Nucleoporin 37 promotes the cell proliferation, migration, and invasion of gastric cancer through activating the PI3K/AKT/mTOR signaling pathway - Jishui Zhang; Wenhao Lv; Yagang Liu; Weihua Fu; Baosheng Chen; Qiutong Ma; Xin Gao; Xiuxia Cui (In Vitro Cellular & Developmental Biology - Animal, 2021)

Genome-wide identification of expansin gene family in barley and drought-related expansins identification based on RNA-seq - Chen Liu; Manman Fu; Fangqi Guo; Chao Wu (Genetica, 2021)

Enhancement of aqueous stability of NH2-MIL-101(Fe) by hydrophobic grafting post-synthetic modification - Jianwei Fu; Lin Wang; Yuheng Chen; Deyi Yan; Huase Ou (Environmental Science and Pollution Research, 2021)

WRF/UCM simulations of the impacts of urban expansion and future climate change on atmospheric thermal environment in a Chinese megacity - Yang Zhao; Lei Zhong; Yaoming Ma; Yunfei Fu; Mingxing Chen; Weiqiang Ma; Chun Zhao; Ziyu Huang; Keqi Zhou (Climatic Change, 2021)

Different Changing Patterns of Three NOS–NO System Activities after Ischemia–Reperfusion in Rabbit with AMI - Jun Zhang; Chao Chen; Fengpeng Li; Guangren Gao; Jinguo Fu; Heping Niu; Kai Yu; Lei Wang; Run Guo; Yanfang Wan; Zhanfeng Ma; Qianyu Zhang; et al. (Cell Biochemistry and Biophysics, 2021)

Study on Tailings Covering System Constructed by Geological Polymerization of Mine Waste, Part 1: Material Characterization and Cover Construction - Yunjian Chen; Senlin Tian; Jiangli Fu; Yichao Lin; Jianhong Huang; Shan Chen; Xuewei Hu (Bulletin of Environmental Contamination and Toxicology, 2021)

Atmospheric brightening counteracts warming‐induced delays in autumn phenology of temperate trees in Europe - Zhaofei Wu; Shouzhi Chen; Hans J. De Boeck; Nils Christian Stenseth; Jing Tang; Yann Vitasse; Shuxin Wang; Constantin Zohner; Yongshuo H. Fu (Global Ecology and Biogeography, 2021)
Aim Ongoing climate warming has been widely reported to delay autumn phenology, which in turn impacts carbon, water, energy and nutrient balances at regional and global scales. However, the underlying mechanisms of autumn phenology responses to climate change have not been fully elucidated. The aims of this study were to determine whether brightening that was defined as the increase of surface solar radiation and warming during recent decades affect autumn phenology in opposite directions and explore the underlying mechanisms. Location Central Europe. Time period 1950–2016. Major taxa studied Four dominant European tree species in central Europe: Aesculus hippocastanum , Betula pendula , Fagus sylvatica and Quercus robur . Methods We investigated the temporal trends of leaf senescence, preseason temperature and radiation by separating the period of 1950–2016 into two sub‐periods (1950–1982 and 1983–2016) and determined the relationship between temperature, radiation and leaf senescence using partial correlation analysis. Results We found a significant warming and brightening trend after the 1980s in central Europe, yet this led to only slight delays in leaf senescence that cannot be explained by the well‐known positive correlation between leaf senescence and autumn warming. Interestingly, we found opposite effects between warming (partial correlation coefficient, r = .37) and brightening ( r = −.23) on leaf senescence. In addition, the temperature sensitivity of leaf senescence decreased with increasing radiation (−5.08 days/℃/10 8 J/m 2 ). Main conclusions The results suggested that brightening accelerated the leaf senescence dates, counteracting the warming‐induced delays in leaf senescence, which may be attributed to photooxidative stress and/or sink limitation. This emphasizes the need to consider radiation to improve the performance of autumn phenology models.

Environmental contamination with SARS‐CoV ‐2 in COVID ‐19 hospitals in Wuhan, China, 2020 - Wei Liu; Dingchen Li; Chaojie Yang; Fangyan Chen; Ruizhong Jia; Leili Jia; Xinyi Xia; Shanhong Fan; Qing Tan; Yuehua Ke; Yong Chen; Haifeng Li; et al. (Environmental Microbiology, 2021)
Summary Coronavirus disease 2019 (COVID‐19) pandemic has caused high number of infections and deaths of healthcare workers globally. Distribution and possible transmission route of SARS‐CoV‐2 in hospital environment should be clarified. We herein collected 431 environmental (391 surface and 40 air) samples in the intensive care unit (ICU) and general wards (GWs) of three hospitals in Wuhan, China from February 21 to March 4, 2020, and detected SARS‐CoV‐2 RNA by real‐time quantitative PCR. The viral positive rate in the contaminated areas was 17.8% (28/157), whereas there was no virus detected in the clean areas. Higher positive rate (22/59, 37.3%) was found in ICU than that in GWs (3/63, 4.8%). The surfaces of computer keyboards and mouse in the ICU were the most contaminated (8/10, 80.0%), followed by the ground (6/9, 66.7%) and outer glove (2/5, 40.0%). From 17 air samples in the contaminated areas, only one sample collected at a distance of around 30 cm from the patient was positive. Enhanced surface disinfection and hand hygiene effectively decontaminated the virus from the environment. This finding might help understand the transmission route and contamination risk of SARS‐CoV‐2 and evaluate the effectiveness of infection prevention and control measures in healthcare facilities.

Coexistence of Candida albicans and Enterococcus faecalis increases biofilm virulence and periapical lesions in rats - Qian Du; Shasha Yuan; Shuangyuan Zhao; Di Fu; Yifei Chen; Yuan Zhou; Yangpei Cao; Yuan Gao; Xin Xu; Xuedong Zhou; Jinzhi He (Biofouling, 2021)

Effects of Food Deprivation Duration on the Behavior and Metabolism of Black Rockfish (Sebastes schlegelii) - Fengyuan Shen; Zonghang Zhang; Yiqiu Fu; Zhen Zhang; Xin Sun; Jianyu Dong; Xiayang Ding; Muyan Chen; Xiumei Zhang (Fishes, 2021)
Fish often undergo food shortages in nature, especially for juveniles that are relatively vulnerable in most aspects. Therefore, the effects of food deprivation on fish behavior and physiology are worth exploring. Here, we investigated the behavioral and metabolic adaptations of the juvenile black rockfish Sebastes schlegelii to different durations of food deprivation. In this study, three treatments were set: control group, short-term food deprivation (STFD) group, and long-term food deprivation (LTFD) group. The rearing lasted for six weeks. During this period, videos were recorded three times per week to assess the locomotor activity and aggression. After this, the fishes’ boldness, neophobia, and aggressiveness were assessed using different behavioral assessment devices, while the standard metabolic rate (SMR) was measured by flow-type respirometry. In general, the values of the four indicators (swimming time, the number of turns, movement number, and attack number) for the STFD group were significantly higher than those for the control and LTFD group during the same period of rearing. In a subsequent personality assessment, the STFD group was observed to be significantly bolder in an assessment measuring boldness than the control and LTFD group (indicated by time in the circle, swimming time, number of times through the circle, and frequency in the circle). The LTFD group was observed to be more exploratory in the assessment of neophobia (indicated by duration in the exploratory area, distance from novelty item, and frequency of stay in the exploratory area). Indeed, the LTFD group was observed to be significantly less aggressive in the assessment of aggressiveness than the control and STFD group (indicated by attack number, attack range frequency, first attack, and winner). SMR was noted to be significantly higher in the STFD group than in the control and LTFD group. In conclusion, this study firstly reported the effects of food deprivation duration on the personalities of black rockfish, as well as the behavioral and physiological mechanisms. Thus, we hope to provide insights into the work of stock enhancement.

Trapping of Microplastics in Halocline and Turbidity Layers of the Semi-enclosed Baltic Sea - Qian Zhou; Chen Tu; Jie Yang; Chuancheng Fu; Yuan Li; Joanna J. Waniek (Frontiers in Marine Science, 2021)
Microplastic pollution in semi-enclosed seas is gaining attention since microplastics are more likely to accumulate there. However, research on the vertical distribution of microplastics and impact factors is still limited. In this study, we focus on the Baltic Sea, which has distinguished salinity stratification, and we assume that the resulting strong density stratification (halocline) can influence the vertical distribution of microplastics in the water column. Therefore, we analyzed the vertical abundance distribution, the composition, and the sizes of microplastics (27.3–5,000.0 μm) in the Baltic Sea. The results showed that microplastics comprising fibers, fragments, and films occurred throughout the water column at an abundance of 1.1–27.7 items L −1 . The abundance of microplastics (3.2–27.7 items L −1 ) at haloclines was significantly higher than those at other water depths except the near surfaces ( p < 0.05), contributing 24.1–53.2% of the microplastics in the whole water column. Small microplastics (<100 μm) were more likely to accumulate in the water layers above halocline. Moreover, the current with high turbidity might be another carrier of microplastics in the near-bottom water layer due to its strong correlation with microplastics abundance. This study provides valuable evidence for the accumulation trend of microplastics in water columns and its influencing factors in the semi-enclosed marginal sea. Further research on the vertical distribution of microplastics under the control of multiple factors should be conducted in the future.

Three new dimeric 2-(2-phenylethyl)chromones from artificial agarwood of Aquilaria sinensis - Pan Xiang; Wen-Hua Dong; Cai-Hong Cai; Wei Li; Li-Man Zhou; Hao-Fu Dai; Hui-Qin Chen; Wen-Li Mei (Natural Product Research, 2021)

A Comparative Analysis of Slack-Based Green Total Factor Productivity in China: a Directional Distance Function - Xuping Zhang; Xiang Chen; Ching-Cheng Lu; Fu-Yueh Cheng (Water, Air, & Soil Pollution, 2021)

Correction to: Considerations for Updates to ICH Q1 and Q5C Stability Guidelines: Embracing Current Technology and Risk Assessment Strategies - Megan E. McMahon; Alexander Abbott; Yelizaveta Babayan; Jenny Carhart; Chi-wan Chen; Elke Debie; Mingkun Fu; Cherokee Hoaglund-Hyzer; Andrew Lennard; Hanlin Li; Tony Mazzeo; Lori McCaig; et al. (The AAPS Journal, 2021)

Considerations for Updates to ICH Q1 and Q5C Stability Guidelines: Embracing Current Technology and Risk Assessment Strategies - Megan E. McMahon; Alexander Abbott; Yelizaveta Babayan; Jenny Carhart; Chi-wan Chen; Elke Debie; Mingkun Fu; Cherokee Hoaglund-Hyzer; Andrew Lennard; Hanlin Li; Tony Mazzeo; Lori McCaig; et al. (The AAPS Journal, 2021)

Reliability of the prediction model for landslide displacement with step-like behavior - Zhiyong Fu; Jingjing Long; Wenqiang Chen; Changdong Li; Haikuan Zhang; Wenmin Yao (Stochastic Environmental Research and Risk Assessment, 2021)

Effect of Palrnatine on lipopolysaccharide-induced acute lung injury by inhibiting activation of the Akt/NF-κB pathway - Xingchi Kan; Yingsheng Chen; Bingxu Huang; Shoupeng Fu; Wenjin Guo; Xin Ran; Yu Cao; Dianwen Xu; Ji Cheng; Zhanqing Yang; Yanling Xu (Journal of Zhejiang University-SCIENCE B, 2021)

Methacrylic functionalized hybrid carbon nanomaterial for the selective adsorption and detection of progesterone in wastewater - Xia Cui; Hua Shu; Lu Wang; Guoning Chen; Jili Han; Qianqian Hu; Kamran Bashir; Zhimin Luo; Chun Chang; Jia Zhang; Qiang Fu (Environmental Science and Pollution Research, 2021)

Effect analysis of pore wall thickness, pore size, and functional group of activated carbon on adsorption behavior based on molecular simulation - Weiqiu Huang; Weihua Chen; Lipei Fu; Yilong Zhang; Nanhua Wu; Jiahui Zhu; Xue Xu; Aihua LYU (Environmental Science and Pollution Research, 2021)

Quantifying glacial elevation changes in the central Qilian Mountains during the early 21st century - Qi-bing Zhang; Cao-hu Mo; Di Zhao; Zong-li Jiang; Zhe-fu Chen; Kun-peng Wu; Zhen Zhang (Journal of Mountain Science, 2021)

Differential metabolism-associated gene expression of duck pancreatic cells in response to two strains of duck hepatitis A virus type 1 - Zhen Chen; Shao-hua Shi; Yu Huang; Cui-qin Huang; Rong-chang Liu; Long-fei Cheng; Guang-hua Fu; Hong-mei Chen; Chun-he Wan; Qiu-ling Fu (Archives of Virology, 2021)
Several outbreaks of duck hepatitis A virus type 1 (DHAV-1), which were characterized by yellow coloration and hemorrhage in pancreatic tissues, have occurred in China. The causative agent is called pancreatitis-associated DHAV-1. The mechanisms involved in pancreatitis-associated DHAV-1 infection are still unclear. Transcriptome analysis of duck pancreas infected with classical-type DHAV-1 and pancreatitis-associated DHAV-1 was carried out. Deep sequencing with Illumina-Solexa resulted in a total of 53.9 Gb of clean data from the cDNA library of the pancreas, and a total of 29,597 unigenes with an average length of 993.43 bp were generated by de novo sequence assembly. The expression levels of D-3-phosphoglycerate dehydrogenase, phosphoserine aminotransferase, and phosphoserine phosphatase, which are involved in glycine, serine, and threonine metabolism pathways, were significantly downregulated in ducks infected with pancreatitis-associated DHAV-1 compared with those infected with classical-type DHAV-1. These findings provide information regarding differences in expression levels of metabolism-associated genes between ducks infected with pancreatitis-associated DHAV-1 and those infected with classical-type DHAV-1, indicating that intensive metabolism disorders may contribute to the different phenotypes of DHAV-1-infection.

A Case Study on MJO Energy Transport Path in a Local Multi-scale Interaction Framework - Yuanwen Zhang; Guiwan Chen; Jian Ling; Shenming Fu; Chongyin Li (Advances in Atmospheric Sciences, 2021)

Optimal Gridding Process for GMI Brightness Temperature Using the Backus-Gilbert Method - Guangcan Chen; Yunfei Fu (Advances in Atmospheric Sciences, 2021)

Accelerated increase in vegetation carbon sequestration in China after 2010: A turning point resulting from climate and human interaction - Yongzhe Chen; Xiaoming Feng; Hanqin Tian; Xutong Wu; Zhen Gao; Yu Feng; Shilong Piao; Nan Lv; Naiqing Pan; Bojie Fu (Global Change Biology, 2021)
China has increased its vegetation coverage and enhanced its terrestrial carbon sink through ecological restoration since the end of the 20th century. However, the temporal variation in vegetation carbon sequestration remains unclear, and the relative effects of climate change and ecological restoration efforts are under debate. By integrating remote sensing and machine learning with a modelling approach, we explored the biological and physical pathways by which both climate change and human activities (e.g., ecological restoration, cropland expansion, and urbanization) have altered Chinese terrestrial ecosystem structures and functions, including vegetation cover, surface heat fluxes, water flux, and vegetation carbon sequestration (defined by gross and net primary production, GPP and NPP). Our study indicated that during 2001–2018, GPP in China increased significantly at a rate of 49.1–53.1 TgC/yr 2 , and the climatic and anthropogenic contributions to GPP gains were comparable (48%–56% and 44%–52%, respectively). Spatially, afforestation was the dominant mechanism behind forest cover expansions in the farming‐pastoral ecotone in northern China, on the Loess Plateau and in the southwest karst region, whereas climate change promoted vegetation cover in most parts of southeastern China. At the same time, the increasing trend in NPP (22.4–24.9 TgC/yr 2 ) during 2001–2018 was highly attributed to human activities (71%–81%), particularly in southern, eastern, and northeastern China. Both GPP and NPP showed accelerated increases after 2010 because the anthropogenic NPP gains during 2001–2010 were generally offset by the climate‐induced NPP losses in southern China. However, after 2010, the climatic influence reversed, thus highlighting the vegetation carbon sequestration that occurs with ecological restoration.

A new ergostane derivative from the leaves of Heynea trijuga Roxburgh - Shou-Bai Liu; Zheng Cui; Hui-Qin Chen; Hao Wang; Wen-Hua Dong; Cai-Hong Cai; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2021)

An atlas of CNV maps in cattle, goat and sheep - Yongzhen Huang; Yunjia Li; Xihong Wang; Jiantao Yu; Yudong Cai; Zhuqing Zheng; Ran Li; Shunjin Zhang; Ningbo Chen; Hojjat Asadollahpour Nanaei; Quratulain Hanif; Qiuming Chen; et al. (Science China Life Sciences, 2021)

Responses of leaf litter decomposability to nitrogen and phosphorus additions are associated with cell wall carbohydrate composition in a subtropical plantation - Xiang-Min Fang; Xiu-Lan Zhang; Ying-Ying Zong; Wen-Qing Li; Jian-Jun Li; Li-Ping Guo; Huimin Wang; Fu-Sheng Chen (Plant and Soil, 2021)

A review of the botany, traditional uses, phytochemistry and pharmacology of Nepeta tenuifolia Briq. - Mingqiu Shan; Yulan Jiang; Yuanyuan Fu; Yongyi Zhou; Zhihui Lu; Sheng Yu; Hui Yan; Chanchan Liu; Peidong Chen; Beihua Bao; Li Zhang; Qinan Wu (Phytochemistry Reviews, 2021)

Pharmacological Activation of RXR-α Promotes Hematoma Absorption via a PPAR-γ-dependent Pathway After Intracerebral Hemorrhage - Chaoran Xu; Huaijun Chen; Shengjun Zhou; Chenjun Sun; Xiaolong Xia; Yucong Peng; Jianfeng Zhuang; Xiongjie Fu; Hanhai Zeng; Hang Zhou; Yang Cao; Qian Yu; et al. (Neuroscience Bulletin, 2021)

Evaluation of the prognostic ability of serum uric acid for elderly acute coronary syndrome patients with diabetes mellitus: a prospective cohort study - Yang Jiao; Jihang Wang; Xia Yang; Mingzhi Shen; Hao Xue; Jun Guo; Wei Dong; Yundai Chen; Qing Xi; Zhenhong Fu (Journal of Zhejiang University-SCIENCE B, 2021)

Creep Properties of Altered Rock Subjected to Water Influx-Lost Cycles - Xuxin Chen; Zhe Qin; Houli Fu (Geotechnical and Geological Engineering, 2021)

Dynamics of antibiotic resistance and its association with bacterial community in a drinking water treatment plant and the residential area - Fu-Yi Huang; Qing-Lin Chen; Xian Zhang; Roy Neilson; Jian-Qiang Su; Shu-Yi-Dan Zhou (Environmental Science and Pollution Research, 2021)

Evaluation of pasture allowance of manganese for ruminants - Xiaoping Ge; Fu Chen; Laraib Saqlain; Jing Ma; Zafar Iqbal Khan; Kafeel Ahmad; Ifra Saleem Malik; Asma Ashfaq; Razia Sultana; Mudasra Munir; Muhammad Nadeem; Muhammad Umer Farooq Awan; et al. (Environmental Science and Pollution Research, 2021)

Increasing mortality caused by chronic obstructive pulmonary disease (COPD) in relation with exposure to ambient fine particulate matters: an analysis in Southeastern China - Zhijian Chen; Qiuli Fu; Guangming Mao; Lizhi Wu; Peiwei Xu; Dandan Xu; Zhifang Wang; Xuejiao Pan; Yuan Chen; Xiaoming Lou; Zhe Mo; Xiaofeng Wang; et al. (Environmental Science and Pollution Research, 2021)

An Investigation of Toxic Metal Levels (Pb, Cd, Cr, As, Hg) in Dried Porphyra and Laminaria Collected from Coastal Cities, China - Yan Chen; Yong-tao Liu; Fu-hua Wang; Dian Wen; Hui Yang; Xiao-li Zhao (Biological Trace Element Research, 2021)

Landslide mapping and analysis along the China-Pakistan Karakoram Highway based on SBAS-InSAR detection in 2017 - Xiao-jun Su; Yi Zhang; Xing-min Meng; Dong-xia Yue; Jin-hui Ma; Fu-yun Guo; Zi-qiang Zhou; Mohib Ur Rehman; Zainab Khalid; Guan Chen; Run-qiang Zeng; Fu-meng Zhao (Journal of Mountain Science, 2021)

An Agrobacterium-mediated non-antibiotic selection-based transformation system for rice (Oryza sativa ssp. indica) cultivar “93-11” successfully produces TAC1-silenced transgenic plants - Jingjing Hou; Hao Chen; Yuzhen Fang; Ying Zhu; Bing Han; Chuanqing Sun; Yongcai Fu (In Vitro Cellular & Developmental Biology - Plant, 2021)

A dissipative particle dynamics simulation of water/oil flow characteristics in nano-sized shale slits - Jiuzhu Wu; Wei Fu; Qun Yan; Yuanyuan Chen; Guangtao Chang; Huixian Zhang (Arabian Journal of Geosciences, 2021)

Suppression of multiple reflection–refraction waves in the shallow low-velocity zone via vertical source combination - Suoliang Chang; Zhen Qu; Sheng Zhang; Yanning Fu; Qiang Chen (Acta Geophysica, 2021)

Expression analysis and tissue localization of IgZ in the grouper Epinephelus coioides after Vibrio alginolyticus infection and vaccination - Yao‐Wu Fu; Zhan‐Juan Yao; Meng‐Han He; Zuo‐Pei Wang; Wei‐Feng Chen; Miao Cui; Qi‐Zhong Zhang (Journal of Fish Diseases, 2021)
The orange‐spotted grouper ( Epinephelus coioides ) is an important marine farmed fish in China. It is affected by the bacterial pathogen Vibrio alginolyticus , which causes high mortality and substantial economic losses. We studied the transcriptional changes of the IgZ gene in E. coioides following V. alginolyticus stimulation and investigated the distribution of IgZ in different tissues. The highest expression level of IgZ occurred in the head kidney. When fish were stimulated with live and inactivated V. alginolyticus , the expression levels of IgZ in the head kidney, spleen, intestine, gills and blood cells were significantly upregulated. In an in situ hybridization study, IgZ mRNA‐positive cells were detected in the head kidney, spleen and gill, but positive signals were not detected in the liver and intestine. IgZ‐labelled cells increased in the head kidney, spleen and gills post‐infection with V. alginolyticus for 21 days. The present study provides additional evidence that IgZ is involved in mucosal immune responses and helps explain the role of IgZ in E . coioides defence against V . alginolyticus infection.

Root trait variation of seed plants from China and the primary drivers - Nannan An; Nan Lu; Bojie Fu; Weiliang Chen; Maierdang Keyimu; Mengyu Wang (Journal of Biogeography, 2021)
Aim Root traits play important roles in plant growth and ecosystem processes. Clarifying the primary drivers of variation in root traits is indispensable for understanding and predicting ecosystem responses to environmental changes. Location China. Taxon Seed plant species. Methods We compiled six key first‐order root traits of 437 seed plant species from different biomes, phylogenetic affiliations, plant growth forms and mycorrhizal types in China. The six root traits included root diameter (RD), root tissue density (RTD), specific root length (SRL), root C content (RCC), root N content (RNC) and root C:N ratio (RCN), which are highly relevant for plant growth rate and resource acquisition. The phylogenetic linear mixed model was employed to examine the effects of climate and soil variables on root traits and to quantify the relative contributions of environment, phylogeny, plant growth form and mycorrhizal type to root trait variation. Results Environment explained most of the variations in RTD and RCC (37.4% and 24.2%, respectively). Mean precipitation of the wettest quarter and mean diurnal temperature range were the main climate drivers of RTD and RCC, respectively. Phylogeny contributed the most to the variation in RD, RNC and RCN (27.0%–52.3%). SRL showed strong links to both environment and phylogeny (35.0% and 27.8%, respectively). However, plant growth form and mycorrhizal type had little effect on root trait variation ( Main conclusions Our study revealed the primary drivers of variations in different root traits of seed plants in China. Climate variability and seasonality variables were more important factors driving root trait variation than the annual averages of temperature and precipitation. Incorporating the different responses of root traits to changing environments and phylogenetic affiliations observed in the present study into terrestrial ecosystem models will improve our ability to predict future vegetation distribution and ecosystem functions under global change.

HDAC inhibitors improve CRISPR-mediated HDR editing efficiency in iPSCs - Jian-Ping Zhang; Zhi-Xue Yang; Feng Zhang; Ya-Wen Fu; Xin-Yue Dai; Wei Wen; Beldon Zhang; Hannah Choi; Wanqiu Chen; Meredith Brown; David Baylink; Lei Zhang; et al. (Science China Life Sciences, 2021)

Lipidomic analyses reveal enhanced lipolysis in planthoppers feeding on resistant host plants - Xiaohong Zheng; Yeyun Xin; Yaxin Peng; Junhan Shan; Ning Zhang; Di Wu; Jianping Guo; Jin Huang; Wei Guan; Shaojie Shi; Cong Zhou; Rongzhi Chen; et al. (Science China Life Sciences, 2021)

Passivation and remediation of Pb and Cr in contaminated soil by sewage sludge biochar tubule - Lin Chen; Qi Ni; Yan Wu; Chuan Fu; Wei Ping; Hongyu Bai; Mengnan Li; Hongcheng Huang; Hanshuang Liu (Environmental Science and Pollution Research, 2021)

Transfer of metal element in soil plant chicken food chain: health risk assessment - Fu Chen; Zille Huma; Zafar Iqbal Khan; Ijaz Rasool Noorka; Kafeel Ahmad; Sonaina Nazar; Humayun Bashir; Mudassra Munir; Jing Ma; Asma Ashfaq; Razia Sultana; Yongjun Yang; et al. (Environmental Science and Pollution Research, 2021)