Microbial functional communities and the antibiotic resistome profile in a high-selenium ecosystem - Yanmei Sun; Jia Guo; Fu Wei; Xiaohui Chen; Meng Li; Chao Li; Size Xia; Guangming Zhang; Wencai You; Xin Cong; Tian Yu; Shiwei Wang (Chemosphere, 2023)

circRNA1149 from Apostichopus japonicus suppresses coelomocyte apoptosis act as miR-92a sponge to regulate Bax expression in response to Vibrio splendidus infection - Ming Guo; Yankai Wang; Xianmu Fu; Wenjun Tao; Chenghua Li (Aquaculture, 2023)

SDGSAT-1: the world’s first scientific satellite for sustainable development goals - Huadong Guo; Changyong Dou; Hongyu Chen; Jianbo Liu; Bihong Fu; Xiaoming Li; Ziming Zou; Dong Liang (Science Bulletin, 2023)

Proteomics revealed the effects of nucleic acid metabolism, transcription and translation on postharvest broccoli senescence under elevated O2 stress - Yuxiao Zhang; Ying Chen; Yanyin Guo; Yangli Ma; Mei Yang; Ruiqing Fu; Yupeng Sun; Jing Qin (Postharvest Biology and Technology, 2023)

The effect of filtration and electrolysis on ballast water treatment - Dongxia Duan; Fengqi Xu; Tingyong Wang; Yu Guo; Hongtian Fu (Ocean Engineering, 2023)

Informing the SWAT model with remote sensing detected vegetation phenology for improved modeling of ecohydrological processes - Shouzhi Chen; Yongshuo H. Fu; Zhaofei Wu; Fanghua Hao; Zengchao Hao; Yahui Guo; Xiaojun Geng; Xiaoyan Li; Xuan Zhang; Jing Tang; Vijay P. Singh; Xuesong Zhang (Journal of Hydrology, 2023)

Variations in and factors controlling soil hydrological properties across different slope aspects in alpine meadows - Licong Dai; Ruiyu Fu; Xiaowei Guo; Yangong Du; Fawei Zhang; Guangmin Cao (Journal of Hydrology, 2023)

Effects of haloxyfop-p-methyl on the developmental toxicity, neurotoxicity, and immunotoxicity in zebrafish - Yi Liu; Jing Guo; Wenjin Liu; Fengjie Yang; Yunyun Deng; Yunlong Meng; Bo Cheng; Jianping Fu; June Zhang; Xinjun Liao; Lili Wei; Huiqiang Lu (Fish & Shellfish Immunology, 2023)

Multiple metals exposure and blood mitochondrial DNA copy number: A cross-sectional study from the Dongfeng-Tongji cohort - Ming Fu; Chenming Wang; Shiru Hong; Xin Guan; Hua Meng; Yue Feng; Yang Xiao; Yuhan Zhou; Chenliang Liu; Guorong Zhong; Yingqian You; Tianhao Wu; et al. (Environmental Research, 2023)

Impact of polystyrene microplastics with combined contamination of norfloxacin and sulfadiazine on Chrysanthemum coronarium L. - Kiran Yasmin Khan; Guanlin Li; Daolin Du; Barkat Ali; Shuang Zhang; Meiying Zhong; Peter Joseph Stoffella; Babar Iqbal; Xiaoqiang Cui; Lijiang Fu; Ya Guo (Environmental Pollution, 2023)

Efficient enrichment of iodine by supported ionic liquid with three effective adsorption sites: Heteroatoms, fused aromatic rings and ionic bond - Yu-Qin Xiang; Yuan-Hao Wang; Hao Chen; Jie Fu; Qiu-Hong Zhu; Xiao-Lan Yang; Xin-Hong Xu; Song Qin; Ling He; Guo-Hong Tao (Chemical Engineering Journal, 2023)

Construction of a novel self-bleaching photochromic hydrogel embraced within the Zn-MOF@WO3 junction for assembling UV-irradiated smart rewritable device - Bingbing Cui; Chuanpan Guo; Zhihong Zhang; Guodong Fu (Chemical Engineering Journal, 2023)

A new multi-identification system based on a poly(l-cysteine) sensor for simultaneous detection of multiple steroid hormones in serum - Xia Cui; Zhimin Luo; Miao Guo; Jiameng Xu; Lu Wang; Guoning Chen; Gege Wang; Chun Chang; Aiguo Zeng; Jia Zhang; Qiang Fu (Chemical Engineering Journal, 2023)

Malate-based polyester chemically shielded metal-phenolic networks coated artificial hair fibers with long-lasting antimicrobial and anti-inflammatory performance - Yue Li; Yong Miao; Lunan Yang; Gaofeng Wang; Meimei Fu; Yue Wang; Danlan Fu; Junfei Huang; Jin Wang; Zhexiang Fan; Zhihui Lu; Jinshan Guo; et al. (Chemical Engineering Journal, 2023)

Cost-effective degradation of pollutants by in-situ electrocatalytic process on Fe@BN-C bifunctional cathode: Formation of 1O2 with high selectivity under nanoconfinement - Pei Su; Wenyang Fu; Xuedong Du; Jieru Guo; Minghua Zhou (Chemical Engineering Journal, 2023)

Efficient inverted CsPbI3 perovskite solar cells fabricated in common air - Chunyan Lu; Xiaodong Li; Xuemin Guo; Sheng Fu; Wenxiao Zhang; Haobo Yuan; Junfeng Fang (Chemical Engineering Journal, 2023)

Ultrahigh ionic conductivity and alkaline tolerance of poly(amidoxime)-based hydrogel for high performance piezoresistive sensor - Xu Guo; Yanfen Lu; Danchen Fu; Chuying Yu; Xinguo Yang; Wenbin Zhong (Chemical Engineering Journal, 2023)

Fabrication of wide-spectra-responsive NA/NH2-MIL-125(Ti) with boosted activity for Cr(VI) reduction and antibacterial effects - Yangjie Fu; Meng Tan; Zhonglu Guo; Derek Hao; Youran Xu; Hao Du; Chao Zhang; Jiayun Guo; Qiang Li; Qi Wang (Chemical Engineering Journal, 2023)

Shape-controlled synthesis of Pd nanotetrahedrons with Pt-doped surfaces for highly efficient electrocatalytic oxygen reduction and formic acid oxidation - Liuxuan Luo; Zehao Tan; Cehuang Fu; Rui Xue; Xiaojing Cheng; Tianzi Bi; Lutian Zhao; Yangge Guo; Xiyang Cai; Jiewei Yin; Shuiyun Shen; Junliang Zhang (Chemical Engineering Journal, 2023)

Responses of soil carbon and nitrogen mineralization to nitrogen addition in a semiarid grassland: The role of season - Xiaobo Yuan; Decao Niu; Ding Guo; Hua Fu (CATENA, 2023)

Storm splitting process and the associated mechanisms for a long-lived hailstorm - Xin Guo; Xueliang Guo; Danhong Fu; Juan Fang (Atmospheric Research, 2023)

Cre-mediated autoexcision of selectable marker genes in soybean, cotton, canola and maize transgenic plants - Xudong Ye; Zarir Vaghchhipawala; Edward J. Williams; Changlin Fu; Jinyuan Liu; Fengming Lu; Erin L. Hall; Shirley X. Guo; LaRee Frank; Larry A. Gilbertson (Plant Cell Reports, 2023)

Dynamic changes in provincial exhaust emissions in China in the carbon peak and neutrality setting: based on the effects of energy consumption and economic growth - Xiaopeng Guo; Yihan Fu; Dongfang Ren; Xinyue Zhang (Environmental Science and Pollution Research, 2023)

Spatial distribution, ecological risk, and human health assessment of heavy metals in lake surface sections — a case study of Qinghai Lake, China - Zheng Li; Zhenghui Fu; Shuhang Wang; Yang Zhang; Jinbo Zhang; Yanxiao Liu; Huaicheng Guo; Pingjian Yang (Environmental Science and Pollution Research, 2023)

Preparation of lignite-loaded nano-FeS and its performance for treating acid Cr(VI)-containing wastewater - Saiou Fu; Junzhen Di; Xuying Guo; Yanrong Dong; Sihang Bao; Hanzhe Li (Environmental Science and Pollution Research, 2023)

Extraction and spatiotemporal changes of open-pit mines during 1985–2020 using Google Earth Engine: A case study of Qingzhou City, Shandong Province, China - Liu Ruifeng; Yuan Kai; Li Xing; Liu Xiaoli; Zhao Xitao; Guo Xiaocheng; Fu Juan; Cao Shixin (Environmental Monitoring and Assessment, 2023)

Evaluating the effects of contact time and leaching solution on measured solubilities of aerosol trace metals - Rui Li; Shuwei Dong; Chengpeng Huang; Feng Yu; Fu Wang; Xiaofei Li; Huanhuan Zhang; Yan Ren; Mingxian Guo; Qingcai Chen; Baozhu Ge; Mingjin Tang (Applied Geochemistry, 2023)

Effects of oxygen content on gaseous and solid products during molten salt oxidation of cation exchange resins - Yun Xue; Yue-Lin Wang; Yang-Hai Zheng; Yu-Sheng Yang; Wen-Da Xu; Yong-De Yan; Ran Zhao; Qing-Guo Zhang; Xin Liu; Fu-Qiu Ma; Mi-Lin Zhang (Environmental Science and Pollution Research, 2022)

Highly efficient removal of hexavalent chromium by magnetic Fe–C composite from reed straw and electric furnace dust waste - Fu-Ping Wang; Ya-Nan Zeng; Yi-Tong Wang; Jun-Guo Li; Xi Zhang; Ai-Min Ji; Le-Le Kang; Rui Ji; Qing Yu; Di Gao; Xiao-Man Wang; Zhen Fang (Environmental Science and Pollution Research, 2022)

Design and Optimization of Multipoint Sampler for Seafloor Sediment Carried by a Deep-Sea Landing Vehicle - Yan Gao; Yue Zhou; Wei Guo; Yifan Fu; Sen Gao; Zhenzhuo Wei; Hongming Sun; Yu Sun (Journal of Marine Science and Engineering, 2022)
The present study proposes a low-energy consumption multipoint sampler carried by a deep-sea landing vehicle (DSLV) to meet the requirements of time series sampling in local areas and location series sampling in wide areas, and an optimization method of sampling structure based on least-squares support-vector machine (LSSVM) surrogate model and a multi-objective particle swarm optimization (MOPSO) algorithm. First, the overall structure and core components, such as the multipoint sampler’s sampling structure, were designed. The optimization variables were the cone angle, sampling tube inner diameter, and sampling tube inner hole length, which were determined by considering the force with which the sampling structure penetrates the seafloor sediment. Then, the sampling process was simulated by the finite element method-smoothed particle hydrodynamics (FEM-SPH) method, while the accurate LSSVM model of force required for sampling and sampling tube volume was established. Finally, the MOPSO algorithm was used for multi-objective optimization of model parameters of sampling structure. The optimal model of sampling structure that can provide theoretical support for the optimal design of multipoint sampler effectively reduces energy consumption and improves sampling efficiency by force required for sampling 25.89% lower and sampling tube volume 34.81% higher than the original model.

Extracellular Mitochondria Activate Microglia and Contribute to Neuroinflammation in Traumatic Brain Injury - Chaonan Zhang; Chuan Liu; Fanjian Li; Mutian Zheng; Yafan Liu; Lei Li; Huaijin Yang; Shu Zhang; Chongjin Wang; Hongtao Rong; Hui Guo; Ying Li; et al. (Neurotoxicity Research, 2022)

Inhibition of Microglial NLRP3 with MCC950 Attenuates Microglial Morphology and NLRP3/Caspase-1/IL-1β Signaling In Stress-induced Mice - Qing Liu; Man-Man Zhang; Min-Xia Guo; Qiu-Ping Zhang; Na-Zhi Li; Jie Cheng; Shi-Le Wang; Guang-Hui Xu; Cheng-Fu Li; Ji-Xiao Zhu; Li-Tao Yi (Journal of Neuroimmune Pharmacology, 2022)

Improving the estimation of ship emissions using the high‐spatiotemporal resolution wind fields simulated by the Weather Research and Forecast model: A case study in China - Xinyi Fu; Dongsheng Chen; Xiurui Guo; Jianlei Lang; Ying Zhou (Journal of Industrial Ecology, 2022)
Ships, sailing in favorable wind or obstructed by wind, will operate with different output power of the engines, and the exhaust emissions will be different even though the ships are sailing at the same ground speed. In this study, the influence of wind was taken into consideration; the ship emission inventory (0.025° × 0.025°) in China of a full year (2014) was reassessed. A speed modification model was employed to figure out the actual output speed of ships by integrating AIS data and the hourly wind. The Weather Research and Forecast (WRF) model was applied to predict the hourly real‐time wind field. The spatial and temporal changes in emissions between the results calculated by the proposed method and our previous study were presented. Overall, when considering the influence of wind, the total ship emissions for the year would increase. In this study, the total estimated emissions of SO 2 , NOx, PM 10 , PM 2.5 , HC, and CO in the area were 1.286 × 10 6 , 2.583 × 10 6 , 2.135× 10 5 , 1.967 × 10 5 , 1.522 × 10 5 , and 3.053 × 10 5 t(metric tons) in 2014, respectively. Under the influence of wind, the proportion of the regions’ emissions to the total was close to that of the previous study. For SO 2 and NOx, emissions presented significant monthly variations. On a monthly timescale, the difference in emissions was more obvious between the results considering and not considering the wind, relative to that on a yearly basis. This study adjusted the method of ship emission estimation, which modified the ship emission inventory over an hourly timescale.

Evolution of the mechanical properties of loess in an acidic water environment: mechanism analysis and prediction using a chemical constitutive model - Yao Zhang; Shaoqiang Guo; Zaiqiang Hu; Ning Li; Shaojun Fu; Shuai Shao; Zhijia Xue (Bulletin of Engineering Geology and the Environment, 2022)

Infestation and distribution of chigger mites on Confucian white-bellied rat (Niviventer confucianus) in Southwest China - Yan-Ling Chen; Xian-Guo Guo; Wen-Yu Song; Tian-Guang Ren; Lei Zhang; Rong Fan; Cheng-Fu Zhao; Zhi-Wei Zhang; Wen-Ge Dong; Xiao-Bin Huang (Biologia, 2022)

The Influence of DO on the Microbiological Community of the A2O Treatment of Municipal Wastewater in Alpine Regions - Mingzhe Guo; Jun Wang; Junhao You; Yongchen Zong; Chunhui Fu (Water, Air, & Soil Pollution, 2022)

Germanium enrichment in sphalerite with acicular and euhedral textures: an example from the Zhulingou carbonate-hosted Zn(-Ge) deposit, South China - Kai Luo; Alexandre Cugerone; Mei-Fu Zhou; Jia-Xi Zhou; Guo-Tao Sun; Jing Xu; Kang-Jian He; Mao-Da Lu (Mineralium Deposita, 2022)

The structure and subduction relicts of the Changchun–Yanji suture, NE China: new evidence from deep seismic reflection profiling - Jiaduo Zhang; Hesheng Hou; Jianbo Zhou; Wei Fu; Rui Guo; Zongdong Pan; Hengcheng Ying (International Journal of Earth Sciences, 2022)

The association between hearing threshold and urinary personal care and consumer product metabolites in middle-aged and elderly people from the USA - Yan-Peng Fu; Wen-Yu Chen; Li-Qing Guo; Ya-Qiong Zhu; Jia-Sheng Yuan; Yue-Hui Liu (Environmental Science and Pollution Research, 2022)

Genistein Alleviates Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus by Activating the Sirt1/Nrf2 Pathway in High Salt-Induced Hypertension - Li-Gang Niu; Na Sun; Kai-Li Liu; Qing Su; Jie Qi; Li-Yan Fu; Guo-Rui Xin; Yu-Ming Kang (Cardiovascular Toxicology, 2022)

The recombinant subunit vaccine encapsulated by alginate‐chitosan microsphere enhances the immune effect against Micropterus salmoides rhabdovirus - Fei‐Fan Xu; Fu‐Yi Jiang; Guo‐Qing Zhou; Jun‐Yao Xia; Fei Yang; Bin Zhu (Journal of Fish Diseases, 2022)
The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China. Vaccination was considered as a potential way to prevent and control this disease. As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA‐CS) are widely used in the development of oral vaccination for fish. Here, we prepared a king of alginate‐chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass. Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA‐CS, G2 and SA‐CS‐G2). The results showed that a stronger immune response including serum antibody levels, immune‐related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune‐related gene ( IgM、IL‐8、IL‐1β、CD4、TGF‐β、TNF‐α ) can be induced obviously with SA‐CS‐G2 groups compared with G2 groups when fish were vaccinated. Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA‐CS‐G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%). This study showed that alginate‐chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.

Antigenic epitope screening and functional modification of mannose enhance the efficacy of largemouth bass virus subunit vaccines - Yi‐Jun Jia; Jun‐Yao Xia; Fu‐Yi Jiang; Yang Li; Guo Chen; Bin Zhu (Journal of Fish Diseases, 2022)
Major capsid protein (MCP) can be used as a subunit vaccine against largemouth bass virus (LMBV). However, subunit vaccines usually have low immunogenicity. Here, to identify the major immunogenicity determinant region of the MCP gene, we truncated the MCP of the LMBV gene into four parts ( MCP ‐ 1, MCP ‐ 2, MCP ‐ 3 and MCP ‐ 4 ). Enzyme‐linked immunosorbent assay (ELISA) was used to identify the antigenicity of these four truncated MCP proteins. Then, the highly antigenic truncated protein was modified with mannose and connected with functionalized single‐walled carbon nanotubes (SWCNTs) as carriers. Largemouth basses were immunized by bath immersion, challenged with LMBV on the 28th day after immunization and evaluated for related immune indicators. The results indicated that the MCP‐2 protein could induce a higher antibody titre than the other truncated MCP proteins. We found that the levels of immune‐related genes ( TNF‐α, CD40 , IgM , IFNγ and IL‐10 ) in the spleen and kidney were significantly increased in the MCP‐2 and MCP‐2‐Man groups. ELISA results showed that the antibody content in the serum increased significantly in the MCP‐2 group 7 days post‐vaccination and increased with days in all the vaccinated groups, with the highest observed on the 21st day. Notably, the MCP‐2‐Man vaccine (10 mg L −1 ) showed durability of immunoprotection efficacy that could protect largemouth basses from LMBV challenge, and the immune protection rate reached 78.94%. These results suggest that MCP‐2 might be the major immunogenicity determinant region of LMBV and that the mannose‐modified MCP‐2 vaccine can induce stronger adaptive immune responses.

New loci for refractive errors and ocular biometric parameters in young Chinese Han adults - Yunyun Sun; Zi-Bing Jin; Shifei Wei; Hongyan Jia; Kai Cao; Jianping Hu; Caixia Lin; Wenzai An; Jiyuan Guo; He Li; Jing Fu; Shi-Ming Li; et al. (Science China Life Sciences, 2022)

Plasma Matrix Metalloproeteinase-9 Is Associated with Seizure and Angioarchitecture Changes in Brain Arteriovenous Malformations - Yo-Tsen Liu; Cheng-Chia Lee; Chun-Fu Lin; Hsiu-Mei Wu; Wan-Yuo Guo; Huai-Che Yang; Feng-Chi Chang; Kang-Du Liou; Chung-Jung Lin (Molecular Neurobiology, 2022)

Evolution stage, spatial and temporal variabilities of granite landforms in the Mount Wugongshan in Jiangxi Province of South China - Le Chai; Cun-di Zhong; Fu-sheng Guo; Xin-shu Huang; Dao-ying Wang; Chong-jian Shao; Liu-qin Chen (Journal of Mountain Science, 2022)

Lockdown-induced Urban Aerosol Change over Changchun, China During COVID-19 Outbreak with Polarization LiDAR - Weiwei Chen; Lingjian Duanmu; Yang Qin; Hongwu Yang; Jing Fu; Chengwei Lu; Wei Feng; Li Guo (Chinese Geographical Science, 2022)

Study on the seasonal variations of dimethyl sulfide, its precursors and their impact factors in the Bohai Sea and North Yellow Sea - Yu Guo; Liying Peng; Zishi Liu; Xiaoting Fu; Guicheng Zhang; Ting Gu; Danyang Li; Jun Sun (Frontiers in Marine Science, 2022)
Dimethyl sulfide (DMS) is one of the most important volatile biogenic sulfur compounds and plays a significant role in global climate change. Studying the seasonal variations and the environmental factors that affect the concentration of DMS would aid in understanding the biogeochemical cycle of sulfur compounds. Using benzene-assisted photoionization positive ion mobility spectrometry (BAPI-PIMS), the seasonal distribution and the key impact factors of DMS and dimethylsulfoniopropionate (DMSP) in the Bohai Sea and North Yellow Sea were investigated in the summer and autumn of 2019. The concentrations of DMS and its precursors, DMSPp and DMSPd, in the surface seawater were 0.11–23.90, 0.67–41.38, and 0.03–12.28 nmol/L, respectively, in summer, and 0.10–20.79, 0.39–13.51, and 0.18–20.58 nmol/L, respectively, in autumn. The air-to-sea exchange flux of DMS was 43.05 ± 44.52 and 34.06 ± 63.38 μmol/(m·d), respectively, in summer and autumn. The results demonstrated that the temperature was the most dominant environmental factor, and the abundance of dinoflagellates was the most dominant biological factor that affected the distribution of DMS and DMSP in summer. The abundance of diatoms was the most dominant biological factor, and the levels of PO 4 3- , NO 2 - , NO 3 - , and SiO 3 2- were the dominant environmental factors that affected the distribution of DMS and DMSP in autumn. These results of this study would be of great significance in understanding the biochemical cycle of DMS in BS and NYS.

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

Effects of tuber size and burial depth on germination and plant growth of the submerged macrophyte Vallisneria spinulosa S.Z. Yan at different light intensities - Guixiang Yuan; Lijun Sun; Peiqin Guo; Zhenglong Chen; Zhenzhi Yang; Hui Fu; Erik Jeppesen (Hydrobiologia, 2022)

Catalytic effect of cesium on the oxidation behavior of cation exchange resins in Li2CO3-Na2CO3-K2CO3 melt - Yang-Hai Zheng; Yong-De Yan; Yun Xue; Yue-Lin Wang; Xin Liu; Wan-Sheng Mi; Qing-Guo Zhang; Yu Li; Fu-Qiu Ma; Mi-Lin Zhang; Zhi-Hao Gan; Kai Zhu (Environmental Science and Pollution Research, 2022)

Seismic performance and reinforcement strategy of frame infilled with ESPS block masonry wall: experimental, theoretical and numerical investigation - Biao Liu; Guo-Liang Bai; Guang-Ming Fu (Bulletin of Earthquake Engineering, 2022)

Development of an Escherichia coli whole cell biocatalyst for the production of hyperoside - Guo-Si Li; Fu-Cheng Zhu; Pei-Pei Wei; Fang-Li Gu; Qi-Ling Xu; Meng-Hua Ma (Biotechnology Letters, 2022)

Zinc Deficiency Aggravates Oxidative Stress Leading to Inflammation and Fibrosis in Lung of Mice - Qirui Zhang; Yao Xue; Yuxin Fu; Bowen Bao; Meng-yao Guo (Biological Trace Element Research, 2022)

Stability Analysis of Surrounding Rock in Underground Chamber Excavation of Coral Reef Limestone - Jing Wu; Hao Fu; Lewen Zhang; Xiangyu Zhang; Deyu Guo (Rock Mechanics and Rock Engineering, 2022)

Efficient ex-vitro rooting and acclimatization for tissue culture plantlets of ginger - Jie Zhou; Fengling Guo; Chuangdong Qi; Jiaping Fu; Ying Xiao; Jinping Wu (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Understorey light environment impacts on seedling establishment and growth in a typhoon-disturbed tropical forest - Kuo-Jung Chao; Yung-Chiau Lin; Guo-Zhang Michael Song; Chien-Hui Liao; Yau-Lun Kuo; Chang-Fu Hsieh; Eugene W. Schupp (Plant Ecology, 2022)

Neuroprotection of Oral Edaravone on Middle Cerebral Artery Occlusion in Rats - Li-Qin Zhao; Ankit Parikh; Yun-Xia Xiong; Qing-Yan Ye; Ying-Guo; Xin-Fu Zhou; Hai-Yun Luo (Neurotoxicity Research, 2022)

Non-peer-reviewed data, effect measures, and meta-regression analysis on proton pump inhibitor use and COVID-19 - Dan-Na Wu; Li-Rong Jiao; Guo-Fu Li; Guo Yu (European Journal of Clinical Pharmacology, 2022)

Fertility conversion between cytoplasmic maintainer lines and restorer lines through molecular marker-assisted selection in pepper (Capsicum annuum L.) - Fu-Sen Ren; Hai-Feng Yang; Yu-Shun Jiao; Rui-Ping Zhang; Zhi-Wei Guo; He-Juan Liu; Qiang Sun; Xi-Jun Li; Xiu-Fang Tan; Bei Zhang; Jun-Qi Zhen; Yan-Qi Dong (Biologia, 2022)

Establishment of a set of wheat-rye addition lines with resistance to stem rust - Chang Liu; Jing Wang; Shulan Fu; Long Wang; Hongwei Li; Mian Wang; Yuhong Huang; Qinghua Shi; Yonghong Zhou; Xianrui Guo; Congle Zhu; Jing Zhang; et al. (Theoretical and Applied Genetics, 2022)

Diminished miR-374c-5p negatively regulates IL (interleukin)-6 in unexplained recurrent spontaneous abortion - Lin Zhao; Li Han; Guozhen Hei; Ran Wei; Zhen Zhang; Xiaoxiao Zhu; Qiang Guo; Chu Chu; Xiaoxiao Fu; Ke Xu; Xia Li (Journal of Molecular Medicine, 2022)

Phenomenon of the sediment deposition in a hydraulic jump region of open channels - Wei-lin Xu; Guo-guang Wang; Shi-hao Fu; Wang-ru Wei (Journal of Mountain Science, 2022)

Directed evolution of the PobR allosteric transcription factor to generate a biosensor for 4-hydroxymandelic acid - YaoYao Liang; Juan Luo; Chenhao Yang; Shuning Guo; Bowen Zhang; Fengqianrui Chen; Kairui Su; Yulong Zhang; Yi Dong; Zhihao Wang; Hongda Fu; Guangchao Sui; et al. (World Journal of Microbiology and Biotechnology, 2022)

Improved and Flexible HDR Editing by Targeting Introns in iPSCs - Juan Fu; Ya-Wen Fu; Juan-Juan Zhao; Zhi-Xue Yang; Si-Ang Li; Guo-Hua Li; Zi-Jun Quan; Feng Zhang; Jian-Ping Zhang; Xiao-Bing Zhang; Chang-Kai Sun (Stem Cell Reviews and Reports, 2022)
Highly efficient gene knockout (KO) editing of CRISPR–Cas9 has been achieved in iPSCs, whereas homology-directed repair (HDR)-mediated precise gene knock-in (KI) and high-level expression are still bottlenecks for the clinical applications of iPSCs. Here, we developed a novel editing strategy that targets introns. By targeting the intron before the stop codon, this approach tolerates reading frameshift mutations caused by nonhomologous end-joining (NHEJ)-mediated indels, thereby maintaining gene integrity without damaging the non-HDR-edited allele. Furthermore, to increase the flexibility and screen for the best intron-targeting sgRNA, we designed an HDR donor with an artificial intron in place of the endogenous intron. The presence of artificial introns, particularly an intron that carries an enhancer element, significantly increased the reporter expression levels in iPSCs compared to the intron-deleted control. In addition, a combination of the small molecules M3814 and trichostatin A (TSA) significantly improves HDR efficiency by inhibiting NHEJ. These results should find applications in gene therapy and basic research, such as creating reporter cell lines.

Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress - Jingjing Lu; Shoupeng Fu; Jie Dai; Jianwen Hu; Shize Li; Hong Ji; Zhiquan Wang; Jiahong Yu; Jiming Bao; Bin Xu; Jingru Guo; Huanmin Yang (Journal of Zhejiang University-SCIENCE B, 2022)

Regulation of Sugar Metabolism by Methyl Jasmonate to Improve the Postharvest Quality of Tomato Fruit - Jiaozhuo Li; Dedong Min; Zilong Li; Xiaodong Fu; Xiuming Zhao; Jihan Wang; Xinhua Zhang; Fujun Li; Xiaoan Li; Yanyin Guo (Journal of Plant Growth Regulation, 2022)

Chronology, geochemical characteristics, and tectonic implications of a Triassic complex in the Rongma Area, Southern Qiangtang, Tibet - Zheng-Zhe Fan; Quan Wang; Xian Chen; Gen-Hou Wang; Yue Fu; Gui-Juan Guo (International Journal of Earth Sciences, 2022)

Rapid triage for ischemic stroke: a machine learning-driven approach in the context of predictive, preventive and personalised medicine - Yulu Zheng; Zheng Guo; Yanbo Zhang; Jianjing Shang; Leilei Yu; Ping Fu; Yizhi Liu; Xingang Li; Hao Wang; Ling Ren; Wei Zhang; Haifeng Hou; et al. (EPMA Journal, 2022)
Background Recognising the early signs of ischemic stroke (IS) in emergency settings has been challenging. Machine learning (ML), a robust tool for predictive, preventive and personalised medicine (PPPM/3PM), presents a possible solution for this issue and produces accurate predictions for real-time data processing. Methods This investigation evaluated 4999 IS patients among a total of 10,476 adults included in the initial dataset, and 1076 IS subjects among 3935 participants in the external validation dataset. Six ML-based models for the prediction of IS were trained on the initial dataset of 10,476 participants (split participants into a training set [80%] and an internal validation set [20%]). Selected clinical laboratory features routinely assessed at admission were used to inform the models. Model performance was mainly evaluated by the area under the receiver operating characteristic (AUC) curve. Additional techniques—permutation feature importance (PFI), local interpretable model-agnostic explanations (LIME), and SHapley Additive exPlanations (SHAP)—were applied for explaining the black-box ML models. Results Fifteen routine haematological and biochemical features were selected to establish ML-based models for the prediction of IS. The XGBoost-based model achieved the highest predictive performance, reaching AUCs of 0.91 (0.90–0.92) and 0.92 (0.91–0.93) in the internal and external datasets respectively. PFI globally revealed that demographic feature age, routine haematological parameters, haemoglobin and neutrophil count, and biochemical analytes total protein and high-density lipoprotein cholesterol were more influential on the model’s prediction. LIME and SHAP showed similar local feature attribution explanations. Conclusion In the context of PPPM/3PM, we used the selected predictors obtained from the results of common blood tests to develop and validate ML-based models for the diagnosis of IS. The XGBoost-based model offers the most accurate prediction. By incorporating the individualised patient profile, this prediction tool is simple and quick to administer. This is promising to support subjective decision making in resource-limited settings or primary care, thereby shortening the time window for the treatment, and improving outcomes after IS.

Toxicities of nanomaterials and metals to rice under low atmospheric pressure - Kerui Guo; Dongheng Fu; Muhammed Adeel; Yunze Shen; Kexiang Wang; Yi Hao; Tonghao Bai; Yaoyao Wang; Yukui Rui (Acta Physiologiae Plantarum, 2022)

Application of RNN on GNSS Reflectometry Sea level monitoring - Nutpapon Limsupavanich; Bofeng Guo; Xiaomei Fu (International Journal of Remote Sensing, 2022)

Reconstruction of chlorophyll-a satellite data in Bohai and Yellow sea based on DINCAE method - Xiaomin Luo; Jun Song; Junru Guo; Yanzhao Fu; Linhui Wang; Yu Cai (International Journal of Remote Sensing, 2022)

Rapid onset hazards, fault-controlled landslides and multi-method emergency decision-making - Fu-yun Guo; Xing-min Meng; Tian-jun Qi; Tom Dijkstra; Jarsve Kristine Thorkildsen; Dong-xia Yue; Guan Chen; Yi Zhang; Xiao-dong Dou; Peng-qing Shi (Journal of Mountain Science, 2022)

Higher temperature sensitivity of flowering than leaf‐out alters the time between phenophases across temperate tree species - Xiaojun Geng; Yongshuo H. Fu; Shilong Piao; Fanghua Hao; Hans J. De Boeck; Xuan Zhang; Shouzhi Chen; Yahui Guo; Janet S. Prevéy; Yann Vitasse; Josep Peñuelas; Ivan A. Janssens; et al. (Global Ecology and Biogeography, 2022)
Aim The aims of this study were to evaluate the changes in the length of the time period between leaf‐out and flowering across temperate tree species, and associate these changes with potential physiological and environmental drivers to enhance mechanistic insight into these phenomena. Location Central Europe. Time period 1980–2016. Major taxa studied Six temperate woody species. Methods Statistical analyses were carried out based on long‐term ground observations of both spring leaf‐out and flowering across temperate tree species during 1980–2016, a period characterized by rapid warming. Results The temperature sensitivity of flowering (−5.4 ± 0.04 days/℃, mean ± SE ) was higher than that of leaf‐out (−4.6 ± 0.04 days/℃) across all species, regardless of whether leaf‐out occurred before or after flowering. This study postulates a hypothesis attributing the different temperature sensitivities to different thermal sensitivities, thermal requirements, and photoperiodic controls. Main conclusions The larger temperature sensitivity of flowering than leaf‐out resulted in an extended time period between flowering and leaf‐out in species that bloom before leafing out, but a shorter time period between these phenophases in species with the opposite strategy. We would like to emphasize the importance of changes in time period between different phenophases, and we recommend conducting experimental research to reveal the underlying mechanisms of plant phenology response to climate change, and to explore its potential ecological implications.

Black-Box Modelling and Prediction of Deep-Sea Landing Vehicles Based on Optimised Support Vector Regression - Hongming Sun; Wei Guo; Yanjun Lan; Zhenzhuo Wei; Sen Gao; Yu Sun; Yifan Fu (Journal of Marine Science and Engineering, 2022)
Due to the nonlinearity of the deep-seafloor and complexity of the hydrodynamic force of novel structure platforms, realising an accurate motion mechanism modelling of a deep-sea landing vehicle (DSLV) is difficult. The support vector regression (SVR) model optimised through particle swarm optimisation (PSO) was used to complete the black-box motion modelling and vehicle prediction. In this study, first, the prototype and system composition of the DSLV were proposed, and subsequently, the high-dimensional nonlinear mapping relationship between the motion state and the driving forces was constructed using the SVR of radial basis function. The high-precision model parameter combination was obtained using PSO, and, subsequently, the black-box modelling and prediction of the vehicle were realised. Finally, the effectiveness of the method was verified through multi-body dynamics simulation and scaled test prototype data. The experimental results confirmed that the proposed PSO–SVR model could establish an accurate motion model of the vehicle, and provided a high-precision motion state prediction. Furthermore, with less calculation, the proposed method can reliably apply the model prediction results to the intelligent behaviour control and planning of the vehicle, accelerate the development progress of the prototype, and minimise the economic cost of the research and development process.

Spatially-explicit quantitative relationship for a potential PES mechanism: Cascade hydropower development in Yarlung Zangbo River Basin, China - Xiao-kang Zhu; Bin Fu; Ramon Felipe Bicudo Da Silva; Ying-man Guo; Chan-yuan Qin; Ting Feng; Hai-bing Yu; Kuang Xiao (Journal of Mountain Science, 2022)

Estimating fractional coverage of crop, crop residue, and bare soil using shortwave infrared angle index and Sentinel-2 MSI - Jibo Yue; Yuanyuan Fu; Wei Guo; Haikuan Feng; Hongbo Qiao (International Journal of Remote Sensing, 2022)

Deep Sea Water Alleviates Tau Phosphorylation and Cognitive Impairment via PI3K/Akt/GSK-3β Pathway - Shan He; Wei-Bing Peng; Xian-Jun Fu; Hong-Lei Zhou; Zhen-Guo Wang (Marine Biotechnology, 2022)

Re-Os Geochronology of the Liuchapo Formation across the Ediacaran-Cambrian Boundary of the Yangtze Block (South China) - Yong Fu; Fuliang Wang; Chuan Guo; Chao Li; Peng Xia (Journal of Earth Science, 2022)
The Ediacaran-Cambrian (E-C) succession in South China records remarkable oceanic, biological and geochemical variations, but it was not well defined geochronologically, which hinders the interpretation of the spatio-temporal seawater chemical architecture during the time E-C interval. This study presents two Re-Os isochron ages of 520.2 ± 6.1 and 561.7 ± 8.5 Ma for the barite-rich black shales from the top Liuchapo and Doushantuo formations respectively in Tianzhu County, Guizhou Province. In combination with existing age data, the two new Re-Os isochron ages suggest that the Liuchapo Formation was deposited between 550 and 520 Ma. Moreover, like the polymetallic Ni-Mo-PGE layers of shelf margin (or platform) facies and V-rich horizons of transitional (or shelf slope) to deep-water facies, the barite deposits were likely formed due to differential mineralization. The timing offset likely resulted from differential elemental concentration related to certain local factors (i.e., hydrothermal fluids, seawater redox and biological activity). The isochron-derived initial 187 Os /188 Os ratios of the top Liuchapo Formation (0.902 ± 0.048) and the Doushantuo Formation (0.740 ± 0.042) fall within the range of continental weathering flux (1.54) and oceanic crust (0.126), implying the involvement of marine hydrothermal fluids. Moreover, their difference of initial 187 Os /188 Os ratios may reflect variations of continental weathering intensity and uplift magnitude.

Distribution of Coomassie Blue Stainable Particles in the Pearl River Estuary, China, Insight Into the Nitrogen Cycling in Estuarine System - Cui-Ci Sun; Wei-Zhong Yue; You-Shao Wang; Wei-Hong He; Yi-Guo Hong; Fu-Lin Sun; Hao Cheng; Mei-Lin Wu; Zhao-Yu Jiang; Fei Jiao; Yu-Tu Wang (Frontiers in Marine Science, 2022)
Distributions of Coomassie Blue stainable particles (CSP), the sources and transports, as well as their implications for nitrogen biogeochemical cycles in the Pearl River estuary (PRE) were investigated during two cruises in August 2016 and January 2017. CSP color concentrations (CSP concentration determined spectrophotometrically) were 73.7–685.3 μg BSA eq L –1 [μg Bovine serum albumin (BSA) equivalent liter –1 ] in August 2016 and 100.6–396.4 μg BSA eq L –1 in January 2017, respectively. CSP concentrations were high in low-salinity waters (<5), and declined from the river to the middle estuary by 80% in the wet season and 55.6% in the dry season, respectively, then increased again in the lower estuary due to high primary production. CSP concentrations were mainly associated with chlorophyll a (Chl a ) concentration except for the turbid mixing zone, suggesting that autochthonous phytoplankton production served as the primary source of CSP in the PRE. The concentrations of nitrogen (N) as CSP in the PRE were comparable to the nitrogen content of particulate hydrolysable amino acids (PHAA). Pictures of CSP taken by microscopy and the correlation between composition of PHAA and the ratio of Chl a /CSP color showed that CSP were relatively degraded due to delivery of old terrestrial protein to river section and extensive microbial degradation during mixing at the upper and middle parts of the estuary, whereas CSP in lower estuary appeared to be more labile due to higher fresh algal production. The contribution of CSP nitrogen (CSP-N) to the particulate nitrogen (PN) pool was 34.98% in summer and 30.8% in winter. The conservative estimate of CSP-N input flux in the Pearl River Delta was about 6 × 10 6 mol N d –1 . These results suggested that CSP was a significant pool of organic nitrogen in the PRE. The study of CSP composition in terms of nitrogen provides new insight into the roles of CSP on nitrogen biogeochemical processes in the turbid and productive estuarine system.

Two new nor -lignans from Selaginella pulvinata (Hook. & Grev.) Maxim and their antihyperglycemic activities - Hua-Wei Lv; Yu-Xia Li; Meng Luo; Jia-Meng Qi; Ze-Fei Fu; Hong-Jian Zhang; Yuan-Qiang Guo; Chu Chu; Han-Bing Li; Ji-Zhong Yan (Natural Product Research, 2022)

SIRT6 Negatively Regulates Schwann Cells Dedifferentiation via Targeting c-Jun During Wallerian Degeneration After Peripheral Nerve Injury - Ying Zou; Jiaqi Zhang; Jingmin Liu; Jiawei Xu; Lanya Fu; Xinrui Ma; Yizhou Xu; Shuyi Xu; Xianghai Wang; Jiasong Guo (Molecular Neurobiology, 2022)

Infestation and distribution of mites on the Yunnan red-backed vole (Eothenomys miletus) in Yunnan Province of southwest China between 2001 and 2015 - Rong Xiang; Xian-Guo Guo; Tian-Guang Ren; Cheng-Fu Zhao; Rong Fan; Zhi-Wei Zhang; Ke-Yu Mao; Pei-Ying Peng; Xiao-Bin Huang; Ti-Jun Qian (Biologia, 2022)

Production of a Class IIb Bacteriocin with Broad-spectrum Antimicrobial Activity in Lactiplantibacillus plantarum RUB1 - Aijuan Wu; Yaqian Fu; Lingyu Kong; Qiyuan Shen; Mingxue Liu; Xiaoqun Zeng; Zhen Wu; Yuxing Guo; Daodong Pan (Probiotics and Antimicrobial Proteins, 2021)

Genome-wide identification of expansin gene family in barley and drought-related expansins identification based on RNA-seq - Chen Liu; Manman Fu; Fangqi Guo; Chao Wu (Genetica, 2021)

Occurrence, source apportionment, and carcinogenic risk assessment of polycyclic aromatic hydrocarbons in urban road dusts in Shanghai - Xue-Tong Wang; Rui Fu; Ying Zhou; Cheng-Lin Wang; Guo-Fa Ren; Xiao-Li Wang; Hui Li (Environmental Science and Pollution Research, 2021)

Different Changing Patterns of Three NOS–NO System Activities after Ischemia–Reperfusion in Rabbit with AMI - Jun Zhang; Chao Chen; Fengpeng Li; Guangren Gao; Jinguo Fu; Heping Niu; Kai Yu; Lei Wang; Run Guo; Yanfang Wan; Zhanfeng Ma; Qianyu Zhang; et al. (Cell Biochemistry and Biophysics, 2021)

Erratum to: Settlement patterns of mountainous half-filled and half-cut widened subgrade with retaining wall - Yong-guo Fu; Xin Jiang; Han-yan Gu; Yan-jun Qiu (Journal of Mountain Science, 2021)

Molecular identification and phylogenetic analysis of fungal pathogens isolated from diseased fish in Xinjiang, China - Yan‐Zhen Zhang; Qing‐Dian Han; Long‐Wei Fu; Yong‐Xing Wang; Zhi‐Hai Sui; Yun‐Guo Liu (Journal of Fish Biology, 2021)
The outbreaks of fungal diseases in cultured fish have been severe in recent years, which is harmful to the healthy and sustainable development of fish farming. In this study, an investigation was conducted for significant fungal infections of 12 species of fish in four regions in Xinjiang, China, to understand the distribution of local fish fungal pathogens. Twenty‐six fungal strains with pathogenicity were isolated, and the challenge experiment showed that eight strains from Changji area had high infection rate to fish eggs. Based on internal transcribed spacer sequence data and molecular analysis, the 26 strains were classified into nine different species of six fungal genera. Phylogenetic analysis showed that all strains were divided into two clades, namely Cluster 1 (contains only the genus Mucor ) and Cluster 2 (consists of five small branches), and the distribution of strains from the same region was scattered in two clusters. There is no strict host selectivity for these fungi to infect fish. Mucor sp. are the main fungal pathogen of fish in these four regions, whereas Hypophthalmichthys molitrix and Carassius auratus are two types of fish that were susceptible to pathogen. In addition, the environmental adaptability experiments showed that eight highly pathogenic strains have different adaptability to the environment, and their optimum temperature and pH were 25°C and 7.0, respectively, whereas the concentration of NaCl was negatively correlated with the growth of strains. Therefore, these results indicated that the coinfection of multiple fungal pathogens in a culture region should be considered in the future study.

Transcriptome analysis reveals differing response and tolerance mechanism of EPSPS and GAT genes among transgenic soybeans - Bing-Fu Guo; Hui-Long Hong; Li-Ping Sun; Yong Guo; Li-Juan Qiu (Molecular Biology Reports, 2021)

Effect of Palrnatine on lipopolysaccharide-induced acute lung injury by inhibiting activation of the Akt/NF-κB pathway - Xingchi Kan; Yingsheng Chen; Bingxu Huang; Shoupeng Fu; Wenjin Guo; Xin Ran; Yu Cao; Dianwen Xu; Ji Cheng; Zhanqing Yang; Yanling Xu (Journal of Zhejiang University-SCIENCE B, 2021)

Responses of leaf litter decomposability to nitrogen and phosphorus additions are associated with cell wall carbohydrate composition in a subtropical plantation - Xiang-Min Fang; Xiu-Lan Zhang; Ying-Ying Zong; Wen-Qing Li; Jian-Jun Li; Li-Ping Guo; Huimin Wang; Fu-Sheng Chen (Plant and Soil, 2021)

Evaluation of the prognostic ability of serum uric acid for elderly acute coronary syndrome patients with diabetes mellitus: a prospective cohort study - Yang Jiao; Jihang Wang; Xia Yang; Mingzhi Shen; Hao Xue; Jun Guo; Wei Dong; Yundai Chen; Qing Xi; Zhenhong Fu (Journal of Zhejiang University-SCIENCE B, 2021)

Landslide mapping and analysis along the China-Pakistan Karakoram Highway based on SBAS-InSAR detection in 2017 - Xiao-jun Su; Yi Zhang; Xing-min Meng; Dong-xia Yue; Jin-hui Ma; Fu-yun Guo; Zi-qiang Zhou; Mohib Ur Rehman; Zainab Khalid; Guan Chen; Run-qiang Zeng; Fu-meng Zhao (Journal of Mountain Science, 2021)

Settlement patterns of mountainous half-filled and half-cut widened subgrade with retaining wall - Yong-guo Fu; Xin Jiang; Han-yan Gu; Yan-jun Qiu (Journal of Mountain Science, 2021)

Projected Increase in Probability of East Asian Heavy Rainy Summer in the 21st Century by CMIP5 Models - Yuanhai Fu; Riyu Lu; Dong Guo (Advances in Atmospheric Sciences, 2021)

Lipidomic analyses reveal enhanced lipolysis in planthoppers feeding on resistant host plants - Xiaohong Zheng; Yeyun Xin; Yaxin Peng; Junhan Shan; Ning Zhang; Di Wu; Jianping Guo; Jin Huang; Wei Guan; Shaojie Shi; Cong Zhou; Rongzhi Chen; et al. (Science China Life Sciences, 2021)

Seasonal variation of flavonoid metabolites in leaves of Liquidambar formosana ‘Nanlinhong’ trees revealed by UPLC-ESI–MS/MS - Jiu-Xin Lai; Fu-Rong Lin; Ping Huang; Wen-Ying Guo; Lie-Bao Han; Yong-Qi Zheng (Brazilian Journal of Botany, 2021)

Functional characterization of TNF‐ α in pufferfish ( Takifugu obscurus ) in immune response and apoptosis against Aeromonas hydrophila - Linghe Kong; Kun Qian; Siwei Wu; Bingxi Li; Zheng Guo; Xiaoxue Yin; Yu Huang; Jianmin Ye; Xiao Tu; Shengli Fu (Journal of Fish Diseases, 2021)
Tumour necrosis factor‐ α (TNF‐ α ) is a multifunctional cytokine involved in immune system homeostasis, antimicrobial defence, regulation of apoptosis, cell proliferation and differentiation. Although the pro‐inflammatory property of TNF‐ α has been made new progress, detailed research on host defence against bacterial infection and inducing apoptosis remains to be revealed in early vertebrates. Here, we reported the TNF‐ α homologue (ToTNF‐ α ) from pufferfish ( Takifugu obscurus ). The open reading frame (ORF) of ToTNF‐α was 753 bp, encoding a protein of 250 aa contained the TNF family signature and conserved cysteine residues. The mRNA expression of ToTNF‐α had a wide range of tested tissues, with the highest expression in the skin. After Aeromonas hydrophila infection, the mRNA expression of ToTNF‐α was significantly up‐regulated both in vivo and in vitro experiments. After stimulation by recombinant protein of ToTNF‐ α ((r)ToTNF‐ α ), the relative expressions of endogenous TNF‐α , caspase 8 , caspase 3 , p53 , and Bax inhibitor‐1 in head kidney leucocytes were all notably up‐regulated. These results showed that ToTNF‐ α might induce apoptosis depend on pro‐ and anti‐apoptotic proteins at mRNA level. Moreover, flow cytometry analysis indicated that the (r)ToTNF‐ α can induce apoptosis of head kidney leucocytes. Taken together, these characteristics suggest that ToTNF‐α can participate in immune response against A. hydrophila and induce apoptosis at mRNA and cellular level, which will help to understand the mechanism of apoptosis and immune response in teleost fish.

Measurement of ice flow velocities from GPS positions logged by short-period seismographs in East Antarctica - Lei Fu; Jingxue Guo; Xiaofei Chen (Science China Earth Sciences, 2021)

Protective effect of myricetin on LPS-induced mastitis in mice through ERK1/2 and p38 protein author - Xingchi Kan; Juxiong Liu; Yingsheng Chen; Wenjin Guo; Dianwen Xu; Ji Cheng; Yu Cao; Zhanqing Yang; Shoupeng Fu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Melatonin-assisted phytoremediation of Pb-contaminated soil using bermudagrass - Chengcheng Xie; Siyi Pu; Xi Xiong; Shuyu Chen; Lingli Peng; Jingyi Fu; Lingxia Sun; Baimeng Guo; Mingyan Jiang; Xi Li (Environmental Science and Pollution Research, 2021)

Effects of the virgin forests to the dissolved organic matters in small forested watershed: a case study of the Tangwang River in Northeast China - Shuhang Wang; Bo Zhang; Zhenghui Fu; Yunyan Guo; Xia Jiang (Environmental Science and Pollution Research, 2021)

Field experiment of rainfall infiltration on a soil slope and simulations based on a water-air two-phase flow model - Gang Liu; Xin-yuan Zha; Jin-kun Guan; Fu-guo Tong (Journal of Mountain Science, 2021)

Diagnosis and Numerical Modeling of an Explosive Cyclone over the Northwestern Pacific - Baitang Sun; Pengyuan Li; Shuqin Zhang; Jingtian Guo; Gang Fu (Journal of Ocean University of China, 2021)

Kynurenine pathway as alternative biosynthetic pathway for fusaric acid in Fusarium oxysporum f.sp. cubense - Tao Zeng; Hui-Cai Zeng; Mei-Ying Fu; Kai-Kun Huang; Jian-Chun Guo; Xin-Wen Hu (Australasian Plant Pathology, 2021)

Neuroprotective carbazole alkaloids from the stems and leaves of Clausena lenis - Gui Yan; Yu-Jie Li; Ying-Ying Zhao; Jia-Ming Guo; Wen-Hao Zhang; Ming-Ming Zhang; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2021)

Systematic analysis of differentially expressed ZmMYB genes related to drought stress in maize - Peng-Yu Zhang; Xiao Qiu; Jia-Xu Fu; Guo-Rui Wang; Li Wei; Tong-Chao Wang (Physiology and Molecular Biology of Plants, 2021)

Soil fertility, enzyme activity, and microbial community structure diversity among different soil textures under different land use types in coastal saline soil - Yun Zhu; Bin Guo; Chen Liu; Yicheng Lin; Qinglin Fu; Ningyu Li; Hua Li (Journal of Soils and Sediments, 2021)

Agarose-based spheroid culture enhanced stemness and promoted odontogenic differentiation potential of human dental follicle cells in vitro - Min Li; Tiwei Fu; Sen Yang; Lanlan Pan; Jing Tang; Meng Chen; Panpan Liang; Zhi Gao; Lijuan Guo (In Vitro Cellular & Developmental Biology - Animal, 2021)

Engineering a heterologous synthetic pathway in Escherichia coli for efficient production of biotin - Pei-Pei Wei; Fu-Cheng Zhu; Cun-Wu Chen; Guo-Si Li (Biotechnology Letters, 2021)

3-Aminopropyltriethoxysilane Complexation with Iron Ion Modified Anode in Marine Sediment Microbial Fuel Cells with Enhanced Electrochemical Performance - Xuerong Zai; Man Guo; Yaokang Hao; Shaoxin Hou; Zhiwei Yang; Jia Li; Yang Li; Hongwei Ji; Yubin Fu (Journal of Ocean University of China, 2021)

Preliminary study on community structures of meiofauna in the middle and eastern Chukchi Sea - Dingyong Huang; Jianjia Wang; Qianhui Zeng; Jiaguang Xiao; Peng Tian; Sujing Fu; Feng Guo; Wentao Niu (Acta Oceanologica Sinica, 2021)

Serological evidence of bovine viral diarrhea virus and peste des petits ruminants virus infection in alpacas (Vicugna pacos) in Shanxi Province, northern China - Qing Liu; Lu Liu; Yu-Kai Meng; Chen Wang; Yu Gao; Fu-Guo Zheng; Hai-Li Ma (Tropical Animal Health and Production, 2021)

A reciprocal egg-swap experiment reveals sources of variation in developmental success among populations of a desert lizard - Xin Hao; Chen-Xu Wang; Xing-Zhi Han; Yang Wang; Qiong Zhang; Fu-Shun Zhang; Bao-Jun Sun; Wei-Guo Du (Oecologia, 2021)

Cryostructures and ground ice content in ice-rich permafrost area of the Qinghai-Tibet Plateau with Computed Tomography Scanning - Xing-wen Fan; Zhan-ju Lin; Ze-yong Gao; Xiang-lian Meng; Fu-jun Niu; Jing Luo; Guo-an Yin; Fu-jun Zhou; Ai-yu Lan (Journal of Mountain Science, 2021)

B3GNT3 acts as a carcinogenic factor in endometrial cancer via facilitating cell growth, invasion and migration through regulating RhoA/RAC1 pathway-associated markers - Ji-Shui Wang; Fang Ruan; Li-Zhu Guo; Feng-Ge Wang; Fu-Ling Wang; Hong-Min An (Genes & Genomics, 2021)

Niacin stimulates EPH4EV mammary epithelial cell proliferation and mammary gland development in pubertal mice through activation of AKT/mTOR and ERK1/2 signaling pathways - Yu Cao; Yan Zhang; Lijun Ma; Jiaxin Wang; Wenjin Guo; Ji Cheng; Guiqiu Hu; Shoupeng Fu; Juxiong Liu (Cell and Tissue Research, 2021)

Correction to: Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Bai; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats - Fang-Fang Wang; Juan Ba; Xiao-Jing Yu; Xiao-Lian Shi; Jin-Jun Liu; Kai-Li Liu; Li-Yan Fu; Qing Su; Hong-Bao Li; Kai B. Kang; Qiu-Yue Yi; Shu-Qiu Wang; et al. (Cardiovascular Toxicology, 2021)

The XGBoost and the SVM-based prediction models for bioretention cell decontamination effect - Xiaocheng Wang; DaFang Fu; Yajun Wang; Ying Guo; Yunfei Ding (Arabian Journal of Geosciences, 2021)

Grape seed proanthocyanidins attenuate apoptosis in ischemic stroke - Kun Fu; Liqiang Chen; Shuai Hu; Yan Guo; Wei Zhang; Yunan Bai (Acta Neurologica Belgica, 2021)

Applied properties and life cycle assessment of flexible packaging lamination processes: a comparative study - Haowei He; Yabo Fu; Youzhong Zhao; Siqi Liu; Guangshen Zuo; Pengfei Guo; Wencai Xu (The International Journal of Life Cycle Assessment, 2021)

Characterization of ZmCOLD1, novel GPCR-Type G Protein genes involved in cold stress from Zea mays L. and the evolution analysis with those from other species - Ya-Nan Jin; Zhen-hai Cui; Ke Ma; Jia-Lu Yao; Yan-Ye Ruan; Zhi-Fu Guo (Physiology and Molecular Biology of Plants, 2021)

Combining targeted sequencing and ultra-low-pass whole-genome sequencing for accurate somatic copy number alteration detection - Junfeng Fu; Weihua Guo; Cheng Yan; Zhenyang Lv; Yu Wang; Ze Wang; Zhe Fan; Ting Lei (Functional & Integrative Genomics, 2021)

A thorough screening based on QTLs controlling zinc and copper accumulation in the grain of different wheat genotypes - Ying Liu; Yaru Chen; Yang Yang; Qiaofeng Zhang; Bisheng Fu; Jin Cai; Wei Guo; Liang Shi; Jizhong Wu; Yahua Chen (Environmental Science and Pollution Research, 2021)

The construction of high precision geostrophic currents based on new gravity models of GOCE and satellite altimetry data - Wenyan Sui; Junru Guo; Jun Song; Zhiliang Liu; Meng Wang; Xibin Li; Yanzhao Fu; Yongquan Li; Yu Cai; Linhui Wang; Lingli Li; Xiaofang Guo; et al. (Acta Oceanologica Sinica, 2021)

Quantitatively determine the dominant driving factors of the spatial—temporal changes of vegetation NPP in the Hengduan Mountain area during 2000–2015 - Shu-ting Chen; Bing Guo; Rui Zhang; Wen-qian Zang; Cui-xia Wei; Hong-wei Wu; Xiao Yang; Xiao-yan Zhen; Xing Li; Da-fu Zhang; Bao-min Han; Hai-ling Zhang (Journal of Mountain Science, 2021)

Decreasing control of precipitation on grassland spring phenology in temperate China - Yongshuo H. Fu; Xuancheng Zhou; Xinxi Li; Yaru Zhang; Xiaojun Geng; Fanghua Hao; Xuan Zhang; Heikki Hanninen; Yahui Guo; Hans J. De Boeck (Global Ecology and Biogeography, 2021)
Aim Vegetation phenology is highly sensitive to climate change. The timing of spring phenology in temperate grasslands is regulated primarily by temperature and precipitation. The aim of this study was to determine whether the primary factor regulating vegetation phenology has changed under ongoing climate change and the underlying mechanisms. Location Temperate semi‐dry grasslands in China. Time period 1982–2015. Major taxa studied Temperate grassland. Methods We extracted start of season (SOS) dates using five standard methods from satellite‐derived normalized difference vegetation index (NDVI) data and determined the primary factor regulating spring phenology using partial correlation analysis. Results The SOS date did not change significantly during the entire 1982–2015 study period in these semi‐dry grasslands, but interannual variability increased significantly from the first subperiod [1982–1998, 8.8 ± 1.1 days (mean ± SE )] to the second subperiod (1999–2015, 10.3 ± 1.1 days). Interestingly, we found that the primary factor regulating SOS shifted from precipitation during 1982–1998 to temperature during 1999–2015. Specifically, we found that during the first period, the SOS in 67.5% of the study area was determined by precipitation (mean partial correlation coefficient, r = 0.58 ± 0.16), but during the second period the main regulating factor in 75.0% of the study area was temperature ( r = 0.61 ± 0.14). Main conclusions The change in the primary driver of spring phenology was attributed mainly to significant increases in preseason precipitation. Our study highlights that the response of spring phenology to climatic factors might change under ongoing climate change. This shift should be addressed in phenology models to simulate grassland phenology better, in addition to its impact on carbon and water cycles in future climate conditions.

Infestation and distribution of gamasid mites on Himalayan field rat (Rattus nitidus) in Yunnan Province of Southwest China - Rong Xiang; Xian-Guo Guo; Cheng-Fu Zhao; Rong Fan; Ke-Yu Mao; Zhi-Wei Zhang; Xiao-Bin Huang (Biologia, 2021)

Distribution, sources, and decomposition of soil organic matter along a salinity gradient in estuarine wetlands characterized by C:N ratio, δ 13 C‐δ 15 N, and lignin biomarker - Shaopan Xia; Zhaoliang Song; Qiang Li; Laodong Guo; Changxun Yu; Bhupinder Pal Singh; Xiaoli Fu; Chunmei Chen; Yidong Wang; Hailong Wang (Global Change Biology, 2021)
Despite increasing recognition of the critical role of coastal wetlands in mitigating climate change, sea‐level rise, and salinity increase, soil organic carbon (SOC) sequestration mechanisms in estuarine wetlands remain poorly understood. Here, we present new results on the source, decomposition, and storage of SOC in estuarine wetlands with four vegetation types, including single Phragmites australis (P, habitat I), a mixture of P. australis and Suaeda salsa (P + S, habitat II), single S. salsa (S, habitat III), and tidal flat (TF, habitat IV) across a salinity gradient. Values of δ 13 C increased with depth in aerobic soil layers (0–40 cm) but slightly decreased in anaerobic soil layers (40–100 cm). The δ 15 N was significantly enriched in soil organic matter at all depths than in the living plant tissues, indicating a preferential decomposition of 14 N‐enriched organic components. Thus, the kinetic isotope fractionation during microbial degradation and the preferential substrate utilization are the dominant mechanisms in regulating isotopic compositions in aerobic and anaerobic conditions, respectively. Stable isotopic (δ 13 C and δ 15 N), elemental (C and N), and lignin composition (inherited (Ad/Al)s and C/V) were not completely consistent in reflecting the differences in SOC decomposition or accumulation among four vegetation types, possibly due to differences in litter inputs, root distributions, substrate quality, water‐table level, salinity, and microbial community composition/activity. Organic C contents and storage decreased from upstream to downstream, likely due to primarily changes in autochthonous sources (e.g., decreased onsite plant biomass input) and allochthonous materials (e.g., decreased fluvially transported upland river inputs, and increased tidally induced marine algae and phytoplankton). Our results revealed that multiple indicators are essential to unravel the degree of SOC decomposition and accumulation, and a combination of C:N ratios, δ 13 C, δ 15 N, and lignin biomarker provides a robust approach to decipher the decomposition and source of sedimentary organic matter along the river‐estuary‐ocean continuum.

Bisabolane sesquiterpenes from Clausena sanki with their potential anti-inflammatory activities - Shi Hu; Yan-Lei Ma; Jia-Ming Guo; Qing Wen; Gui Yan; Shuo Yang; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2020)

Development of a minimized model structure and a feedback control framework for regulating photosynthetic activities - Lijiang Fu; Govindjee Govindjee; Jinglu Tan; Ya Guo (Photosynthesis Research, 2020)

Safety of protease inhibitors and Arbidol for SARS-CoV-2 pneumonia in Zhejiang Province, China - Yong-zheng Guo; Kai-jin Xu; Yong-tao Li; Jia-dan Fu; Min Xu; Ling Yu; Ji-fang Sheng; Biao Zhu (Journal of Zhejiang University-SCIENCE B, 2020)

Effects of the Deviatoric Stress Ratio on the Coal Failure and Permeability During Deep Mining - Chao Xu; Qiang Fu; Kai Wang; Chaofei Guo; Xiaofang Li (Geotechnical and Geological Engineering, 2020)

Analysis of landslide stability under seismic action and subsequent rainfall: a case study on the Ganjiazhai giant landslide along the Zhaotong-Qiaojia road during the 2014 Ludian earthquake, Yunnan, China - Xiaodong Fu; Qian Sheng; Guo Li; Zhenping Zhang; Yongqiang Zhou; Yuxiang Du (Bulletin of Engineering Geology and the Environment, 2020)

SNP of AHSA2 gene in three cattle breeds using snapshot technology - Shu-Zhu Cheng; E. Guang-Xin; Cheng-Li Liu; Wang-Dui Basang; Yan-Bin Zhu; Ri-Su Na; Yan-Guo Han; Yan Zeng; Xiao Wang; Wei-Wei Ni; Bai-Gao Yang; Xing-Hai Duan; et al. (Journal of Genetics, 2020)

Application of multi-component joint inversion in oil and gas exploration: A case study of reservoir and gas saturation prediction of the Xujiahe formation in the PLN area of the central Sichuan Basin - Dong Wang; Zhen-Hua He; Xu-Ben Wang; Le Li; Hai-Tao Yang; Zhi-Guo Fu; Hong-Yan Wang (Applied Geophysics, 2020)

Effect of various doses of 3,4-dimethylpyrazole phosphate on mineral nitrogen losses in two paddy soils - Hua Li; Xiaodong Chen; Chen Liu; Shaoxian Wang; Bin Guo; Ningyu Li; Yuequn Jin; Qinglin Fu; Xinqiang Liang (Journal of Soils and Sediments, 2020)

La(OH)3-modified magnetic sodium carboxymethyl cellulose for sequential removal of pollutants: adsorption of phosphate and subsequent photocatalytical reduction of Cr(VI) - Taiwan Liao; Pengwei Huang; Huiyu Song; Jia Guo; Xionghui Fu; Xiang Yu; Liang Peng; Boping Han; Yi Zhu; Yuanming Zhang (Environmental Science and Pollution Research, 2020)

Reexamining the Necessity of Adding Water Curtain Borehole with Improved Understanding of Water Sealing Criterion - Qi-Hua Zhang; Qing-Bing Liu; Guo-Fu He (Rock Mechanics and Rock Engineering, 2020)

Design and implementation of a novel wireless modular capsule robotic system in pipe - Jian Guo; Zihong Bao; Qiang Fu; Shuxiang Guo (Medical & Biological Engineering & Computing, 2020)

The Cumulative Effects of Fishing, Plankton Productivity, and Marine Mammal Consumption in a Marine Ecosystem - Caihong Fu; Yi Xu; Chuanbo Guo; Norm Olsen; Arnaud Grüss; Huizhu Liu; Nicolas Barrier; Philippe Verley; Yunne-Jai Shin (Frontiers in Marine Science, 2020)

Progress in plant phenology modeling under global climate change - Yongshuo Fu; Xinxi Li; Xuancheng Zhou; Xiaojun Geng; Yahui Guo; Yaru Zhang (Science China Earth Sciences, 2020)

Dynamic Change of Shanks Gene mRNA Expression and DNA Methylation in Epileptic Rat Model and Human Patients - Yujiao Fu; Du Liu; Jialing Guo; Hongyu Long; Wenbiao Xiao; Wei Xiao; Li Feng; Zhaohui Luo; Bo Xiao (Molecular Neurobiology, 2020)

The effect of baicalin on microRNA expression profiles in porcine aortic vascular endothelial cells infected by Haemophilus parasuis - Shulin Fu; Jun Liu; Jianfeng Xu; Sanling Zuo; Yunfei Zhang; Ling Guo; Yinsheng Qiu; Chun Ye; Yu Liu; Zhongyuan Wu; Yongqing Hou; Chien-An Andy Hu (Molecular and Cellular Biochemistry, 2020)

Responses of Denitrification Rate and Denitrifying Bacterial Communities Carrying nirS and nirK Genes to Grazing in Peatland - Xin Fang; Rongbo Zheng; Xuelian Guo; Qian Fu; Kun Zhang (Journal of Soil Science and Plant Nutrition, 2020)

Ecological analysis of gamasid mites on the body surface of Norway rats (Rattus norvegicus) in Yunnan Province, Southwest China - Zhe Liu; Xian-Guo Guo; Rong Fan; Cheng-Fu Zhao; Ke-Yu Mao; Zhi-Wei Zhang; Yue Zhao (Biologia, 2020)

Responses of Primary Afferent Fibers to Acupuncture-Like Peripheral Stimulation at Different Frequencies: Characterization by Single-Unit Recording in Rats - Ran Huo; Song-Ping Han; Feng-Yu Liu; Xiao-Jing Shou; Ling-Yu Liu; Tian-Jia Song; Fu-Jun Zhai; Rong Zhang; Guo-Gang Xing; Ji-Sheng Han (Neuroscience Bulletin, 2020)

A new 5α,8α-epidioxysterol with immunosuppressive activity from the South China Sea soft coral Sinularia sp. - Min Yang; Lin-Fu Liang; Heng Li; Wei Tang; Yue-Wei Guo (Natural Product Research, 2020)

Transferability of a Conceptual Hydrological Model across Different Temporal Scales and Basin Sizes - Sheng Sheng; Hua Chen; Fu-Qiang Guo; Jie Chen; Chong-Yu Xu; Sheng-lian Guo (Water Resources Management, 2020)

The trichome-specific acetolactate synthase NtALS1 gene, is involved in acylsugar biosynthesis in tobacco (Nicotiana tabacum L.) - Ai-Xia Chang; Biao Chen; Ai-Guo Yang; Ri-Sheng Hu; Quan-Fu Feng; Ming Chen; Xiao-Ning Yang; Cheng-Gang Luo; Yang-Yang Li; Yuan-Ying Wang (Planta, 2020)

In vitro polyploid induction using colchicine for Zingiber Officinale Roscoe cv. ‘Fengtou’ ginger - Jie Zhou; Fengling Guo; Jiaping Fu; Ying Xiao; Jinping Wu (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Investigation of a loess-mudstone landslide and the induced structural damage in a high-speed railway tunnel - Shunhua Zhou; Zhiyao Tian; Honggui Di; Peijun Guo; Longlong Fu (Bulletin of Engineering Geology and the Environment, 2020)

Analysis of the regional spectral properties in northwestern South China Sea based on an empirical orthogonal function - Dongyang Fu; Yuye Huang; Dazhao Liu; Shan Liao; Guo Yu; Xiaolong Zhang (Acta Oceanologica Sinica, 2020)

3D-QSAR, HQSAR, molecular docking, and new compound design study of 1,3,6-trisubstituted 1,4-diazepan-7-ones as human KLK7 inhibitors - Le Fu; Yi Chen; Chun-mei Xu; Tao Wu; Hong-mei Guo; Zhi-hua Lin; Rui Wang; Mao Shu (Medicinal Chemistry Research, 2020)

Complete genome sequence of a novel bovine hepacivirus from Yunnan, China - Xin Qiang; Xueying Shen; Honghong Peng; Xiaofang Guo; Zhihai He; Mingguo Yao; Guozhang Fu; Yujun Cui; Xianglilan Zhang; Yong Huang; Hang Fan; Chunhong Du; et al. (Archives of Virology, 2020)

Epidemiology and HBGA-susceptibility investigation of a G9P[8] rotavirus outbreak in a school in Lechang, China - Lun-Ai Guo; Meng Zhang; Yu-zhen Hou; Haitao Hu; Ling Fang; Ming Tan; Qiong Huang; Hui Li; Li-Mei Sun; Xi Jiang; Wen-Fang Tan; Shixing Tang; et al. (Archives of Virology, 2020)

Response of individual sizes and spatial patterns of Deyeuxia angustifolia to increasing water level gradient in a freshwater wetland - Heng Ren; Fu-xi Shi; Rong Mao; Yue-dong Guo; Wen-zhi Zhao (Environmental Science and Pollution Research, 2020)

Correction to: Transcriptomic Profiling Provides Insights into Inbreeding Depression in Yesso Scallop Patinopecten yessoensis - Liang Zhao; Yangping Li; Jiarun Lou; Zhihui Yang; Huan Liao; Qiang Fu; Zhenyi Guo; Shanshan Lian; Xiaoli Hu; Zhenmin Bao (Marine Biotechnology, 2020)

Species richness and biodiversity significance of alpine micro-waterbody systems in Gaoligong Mountain, Northwest Yunnan, China - Shuo-Ran Liu; Davide Fornacca; Dao-De Yang; Lu Tan; Xian-Fu Li; Guo-Peng Ren; Jun Sun; Xiao-Yang He; Wen-Shu Yang; Qing-Hua Cai; Wen Xiao (Journal of Mountain Science, 2020)

Temporal and Spatial Dynamics of Astroglial Reaction and Immune Response in Cuprizone-Induced Demyelination - Jun An; Jun-Jun Yin; Yan He; Ruo-Xuan Sui; Qiang Miao; Qing Wang; Jie-Zhong Yu; Jing-Wen Yu; Fu-Dong Shi; Cun-Gen Ma; Bao-Guo Xiao (Neurotoxicity Research, 2020)

Long-term shifts in abundance of (migratory) crop-feeding and beneficial insect species in northeastern Asia - Jianglong Guo; Xiaowei Fu; Shengyuan Zhao; Xiujing Shen; Kris A. G. Wyckhuys; Kongming Wu (Journal of Pest Science, 2020)
Vast numbers of insects annually engage in trans-latitudinal migration and thereby impact structure and functioning of natural and man-made ecosystems. In eastern Asia, long-distance migration has historically been studied for single insect species rather than diverse species complexes. Here, we assessed migration dynamics of multiple economically important migratory species on an island in the Bohai Strait, China. Drawing upon 15-year trapping records of > 2.5 million specimens, we unveil inter- and intra-annual shifts in the species composition and abundance of migrant individuals. Migrants belonged to 9 orders and 36 families, primarily consisting of Lepidoptera (79% individuals), Odonata (8%), and Coleoptera (4%). Seven crop-feeding noctuids, e.g., Helicoverpa armigera (Hübner), Mythimna separata (Walker), represented 54% of the total trapping records. Trap catches exhibited marked seasonal variation, with the highest capture rate during early fall. Yearly abundance of migratory noctuids was coupled with that of their associated natural enemies. Although overall trap catches did not decrease over the monitoring period, the entire order of Odonata experienced a 14.1% annual rate of decline. Furthermore, 19 out of 108 species exhibited a progressively declining abundance over time, including the cosmopolitan cutworm Agrotis ipsilon (Hufnagel) and the insectivorous dragonfly Pantala flavescens Fabricius. Our work provides unprecedented insights into insect migration dynamics in eastern Asia, helps fine-tune forecasting and early-warning systems of crop pests, and thereby guides integrated pest management within local agro-landscapes. Also, a long-term tracking of migrant insect populations can shine light on the fate of (insect-mediated) ecosystem services and trophic dynamic processes at a macroscale.

Groundwater pollution source apportionment using principal component analysis in a multiple land-use area in southwestern China - Qiling Li; Han Zhang; Shanshan Guo; Kang Fu; Lei Liao; Yi Xu; Siqian Cheng (Environmental Science and Pollution Research, 2020)

Physical Model Experimental Study on Spalling Failure Around a Tunnel in Synthetic Marble - Guo-Qiang Zhu; Xia-Ting Feng; Yang-Yi Zhou; Zheng-Wei Li; Lian-Jie Fu; Yong-Run Xiong (Rock Mechanics and Rock Engineering, 2020)

Identification of De Novo JAK2 and MAPK7 Mutations Related to Autism Spectrum Disorder Using Whole-Exome Sequencing in a Chinese Child and Adolescent Trio-Based Sample - Jian Jiao; Manxue Zhang; Pingyuan Yang; Yan Huang; Xiao Hu; Jia Cai; Chan Yang; Mingjing Situ; Hui Zhang; Lei Fu; Kuifang Guo; Yi Huang (Journal of Molecular Neuroscience, 2020)
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with high phenotypic and genetic heterogeneity. Whole-exome sequencing studies have shown that de novo single-nucleotide variations (SNVs) play an important role in sporadic ASD. The present study aimed to search for de novo SNVs using whole-exome sequencing in 59 unrelated Chinese ASD sporadic trios, and found 24 genes (including five reported ASD candidate genes CACNA1D , ACHE , YY1 , TTN , and FBXO11 ) with de novo harmful SNVs. Five genes ( CACNA1D , JAK2 , ACHE , MAPK7 , and PRKAG2 ) classified as “medium-confidence” genes were found to be related to ASD using the Phenolyzer gene analysis tool, which predicts the correlation between the candidate genes and the ASD phenotype. De novo SNVs in JAK2 , MAPK7 , and PRKAG2 were first found in ASD. Both JAK2 and MAPK7 were involved in the regulation of the MAPK signaling pathway. Gene co-expression and inter-gene interaction networks were constructed and gene expression data in different brain regions were further extracted, revealing that JAK2 and MAPK7 genes were associated with certain previously reported ASD genes and played an important role in early brain development. The findings of this study suggest that the aforementioned five reported ASD genes and JAK2 and MAPK7 may be related to ASD susceptibility. Further investigations of expression studies in cellular and animal models are needed to explore the mechanism underlying the involvement of JAK2 and MAPK7 in ASD.

Isolation, identification and character analysis of Streptococcus dysgalactiae from Megalobrama terminalis - Fei Zhao; Shan He; Ai‐ping Tan; Xue‐zhong Guo; Lan Jiang; Cui Liu‐Fu; Yu‐ting Deng; Rui‐quan Zhang (Journal of Fish Diseases, 2020)
Pure bacterial cultures were isolated from different tissues of moribund Megalobrama terminalis from a high mortality event that occurred at a farm in Foshan, China. Two isolates (F2 and F3) were identified as Streptococcus dysgalactiae subsp. dysgalactiae based on morphological and biochemical detection as well as molecular analysis. In brain heart infusion broth, the best growth conditions of isolate F3 were 35ºC, salinity 5‰ and pH 7. Furthermore, infection with isolate F3 (1.2 × 10 6 CFU/fish) led to the death of M. terminalis and zebrafish ( Danio rerio ). However, isolate F3 had no obvious pathogenicity to tilapia (GIFT, Oreochromis niloticus ). When the water temperature was 29ºC, the corresponding mortality rates for zebrafish infected by isolate F3 were higher than those at 23ºC. Culture for 24 and 72 hr with isolate F3 resulted in the same mortality rates for zebrafish. The antimicrobial susceptibility assay revealed that isolate F3 was susceptible to ampicillin, florfenicol and several other antibiotics but resistant to nalidixic acid, streptomycin, sulfamethoxazole/trimethoprim, neomycin and amikacin. To our knowledge, this is the first report that S. dysgalactiae infected the subtropical freshwater fish M. terminalis , which indicates that this bacterium is a potential threat to subtropical freshwater fish.

EFFECT OF A ROOT‐ZONE INJECTION IRRIGATION METHOD ON WATER PRODUCTIVITY AND APPLE PRODUCTION IN A SEMI‐ARID REGION IN NORTH‐WESTERN CHINA - Yan‐Ping Wang; Lin‐Sen Zhang; Yan Mu; Wei‐Hong Liu; Fu‐Xing Guo; Tian‐Ran Chang (Irrigation and Drainage, 2020)
Within the Chinese Loess Plateau, water resources are scarce and irrigation efficiency is a challenging issue. Traditional surface drip irrigation (SDI) methods have failed to improve irrigation efficiency and reduce surface evaporation in the region. An easy‐to‐install and practicable root‐zone injection irrigation (RII) method, with a low risk of emitter clogging and which uses subsurface infiltration‐promoting apparatuses (SIPA) to deliver water directly to the root zone, was designed and tested in an apple orchard over 3 years in northern Shaanxi, China. In the 0–0.6 m soil layer (where the apple roots are concentrated), the RII method produced consistently higher soil water content than the SDI method over all three growing seasons. The soil water content was consistently higher than 60% of field capacity, thus meeting the water requirements of fruit‐bearing apple trees. In addition, the RII method alleviated soil desiccation, significantly increased apple yields and improved fruit quality compared with the SDI method using the same volume of irrigation water. Both irrigation efficiency and water‐use efficiency were improved with the RII method. These results provide a theoretical basis for the utilization of the RII irrigation method in apple orchards in semi‐arid regions, which may improve water conservation and the sustainability of apple production. © 2019 John Wiley & Sons, Ltd.

The acclimation of leaf photosynthesis of wheat and rice to seasonal temperature changes in T‐FACE environments - Chuang Cai; Gang Li; Lijun Di; Yunjie Ding; Lin Fu; Xuanhe Guo; Paul C. Struik; Genxing Pan; Haozheng Li; Weiping Chen; Weihong Luo; Xinyou Yin (Global Change Biology, 2020)
Crops show considerable capacity to adjust their photosynthetic characteristics to seasonal changes in temperature. However, how photosynthesis acclimates to changes in seasonal temperature under future climate conditions has not been revealed. We measured leaf photosynthesis ( A n ) of wheat ( Triticum aestivum L.) and rice ( Oryza sativa L.) grown under four combinations of two levels of CO 2 (ambient and enriched up to 500 µmol/mol) and two levels of canopy temperature (ambient and increased by 1.5–2.0°C) in temperature by free‐air CO 2 enrichment (T‐FACE) systems. Parameters of a biochemical C 3 ‐photosynthesis model and of a stomatal conductance ( g s ) model were estimated for the four conditions and for several crop stages. Some biochemical parameters related to electron transport and most g s parameters showed acclimation to seasonal growth temperature in both crops. The acclimation response did not differ much between wheat and rice, nor among the four treatments of the T‐FACE systems, when the difference in the seasonal growth temperature was accounted for. The relationships between biochemical parameters and leaf nitrogen content were consistent across leaf ranks, developmental stages, and treatment conditions. The acclimation had a strong impact on g s model parameters: when parameter values of a particular stage were used, the model failed to correctly estimate g s values of other stages. Further analysis using the coupled g s –biochemical photosynthesis model showed that ignoring the acclimation effect did not result in critical errors in estimating leaf photosynthesis under future climate, as long as parameter values were measured or derived from data obtained before flowering.

Strong genetic differentiation of the clam Meretrix lamarckii in the China Sea revealed by mitochondrial DNA marker - Jiantong Feng; Zeqin Fu; Yahong Guo; Jiji Li; Baoying Guo; Zhenming Lü; Yingying Ye (Molecular Biology Reports, 2020)

Geographically isolated Colorado potato beetle mediating distinct defense responses in potato is associated with the alteration of gut microbiota - Jie Wang; Zhou Gao; Mingyu Yang; Rongrong Xue; Hui Yan; Kaiyun Fu; Zhaojuan Zhang; Wenchao Guo; Gary W. Felton; Rensen Zeng (Journal of Pest Science, 2020)

Differences in root surface adsorption, root uptake, subcellular distribution, and chemical forms of Cd between low- and high-Cd-accumulating wheat cultivars - Ya-Tao Xiao; Zhen-Jie Du; Carlos-A Busso; Xue-Bin Qi; Hai-Qing Wu; Wei Guo; Da-Fu Wu (Environmental Science and Pollution Research, 2020)

Characteristics and Prognosis of Talaromyces marneffei Infection in Non-HIV-Infected Children in Southern China - Jing Guo; Bing-Kun Li; Tian-Min Li; Fang-Lin Wei; Yu-Jiao Fu; Yan-Qing Zheng; Kai-Su Pan; Chun-Yang Huang; Cun-Wei Cao (Mycopathologia, 2019)

Knowledge-Based Identification and Damage Detection of Bridges Spanning Water via High-Spatial-Resolution Optical Remotely Sensed Imagery - Chao Chen; Jiaoqi Fu; Nan Lu; Yanli Chu; Jiachen Hu; Biyun Guo; Xin Zhao (Journal of the Indian Society of Remote Sensing, 2019)

Can smart factories bring environmental benefits to their products?: A case study of household refrigerators - Wujie Zhang; Fu Gu; Jianfeng Guo (Journal of Industrial Ecology, 2019)
Smart factories have been widely adopted as a new manufacturing paradigm, in which the state‐of‐the‐art technologies are introduced to improve relevant processes. Yet, whether smart factories affect the environmental performance remains unknown. In this article, we examine the environmental performance of a smart refrigerator factory by comparing the environmental impacts of its product to a similar model that is produced in a traditional fashion. This article quantifies and verifies the theoretically predicted impacts of this smart factory on the individual processes. Though the overall differences in the two models are quite minor, we find that this smart factory can notably reduce the values of most impact categories associated with the parts and refrigerator production; the reduction in the value of climate change is 33%. Owing to higher material efficiency—raw material savings in this smart factory contributes to the greatest reductions in most categorized impacts—the contribution to the reduction of climate change is 39%. Yet, all categorized impacts of procurement and delivery are increased due to product personalization and direct delivery. The results of sensitivity analysis show that promoting product modularity, adopting clean energy such as wind power can further improve the environmental performance of the selected refrigerator. The introduction of auxiliary equipment and systems slightly increases the value of each category; yet their impacts are negligible compared to their benefits as facilitating production efficiency. Based on the quantitative results, recommendations are given to improve the environmental performance of smart factory, including optimizing current strategies and promoting horizontal and end‐to‐end integration.

Resistance reported from China antimicrobial surveillance network (CHINET) in 2018 - Fupin Hu; Yan Guo; Yang Yang; Yonggui Zheng; Shi Wu; Xiaofei Jiang; Demei Zhu; Fu Wang (European Journal of Clinical Microbiology & Infectious Diseases, 2019)

Ureteral involvement by metastatic malignant disease - Jieping Hu; Jun Deng; Ju Guo; Bin Fu (Clinical & Experimental Metastasis, 2019)

Se Regulates the Contractile Ability of Uterine Smooth Musclevia Selenoprotein N, Selenoprotein T, and Selenoprotein Win Mice - Fu-han Wang; Xiao Peng; Yu Chen; Ying Wang; Mei Yang; Meng-yao Guo (Biological Trace Element Research, 2019)

The protective function of non-coding DNA in DNA damage accumulation with age and its roles in age-related diseases - Guo-Hua Qiu; Xintian Zheng; Mingjun Fu; Cuiqin Huang; Xiaoyan Yang (Biogerontology, 2019)

The synergetic effect of pelvic rotation and X-ray offset on radiographic angles of the acetabular cup - Jing-Xin Zhao; Xiu-Yun Su; Zhe Zhao; Ruo-Xiu Xiao; Guo-Fei Sun; Li-Cheng Zhang; Pei-Fu Tang (Medical & Biological Engineering & Computing, 2019)

Photoelectrocatalytic degradation of atrazine by boron-fluorine co-doped TiO2 nanotube arrays - He-xuan Wang; Li-nan Zhu; Fu-qiao Guo (Environmental Science and Pollution Research, 2019)

Extracellular production of recombinant N-glycosylated anti-VEGFR2 monobody in leaky Escherichia coli strain - Ning Ding; Xin Fu; Yao Ruan; Jing Zhu; Pingping Guo; Lichi Han; Jianing Zhang; Xuejun Hu (Biotechnology Letters, 2019)

Transcriptomic Profiling Provides Insights into Inbreeding Depression in Yesso Scallop Patinopecten yessoensis - Liang Zhao; Yangping Li; Jiarun Lou; Zhihui Yang; Huan Liao; Qiang Fu; Zhenyi Guo; Shanshan Lian; Xiaoli Hu; Zhemin Bao (Marine Biotechnology, 2019)

Carbon Monoxide Attenuates High Salt-Induced Hypertension While Reducing Pro-inflammatory Cytokines and Oxidative Stress in the Paraventricular Nucleus - Dong-Dong Zhang; Yan-Feng Liang; Jie Qi; Kai B. Kang; Xiao-Jing Yu; Hong-Li Gao; Kai-Li Liu; Yan-Mei Chen; Xiao-Lian Shi; Guo-Rui Xin; Li-Yan Fu; Yu-Ming Kang; et al. (Cardiovascular Toxicology, 2019)

Potential use of high-throughput sequencing of bacterial communities for postmortem submersion interval estimation - Jing He; Juanjuan Guo; Xiaoliang Fu; Jifeng Cai (Brazilian Journal of Microbiology, 2019)

Ac25 in Autographa californica multiple nucleopolyhedrovirus was crucial for progeny budded virion production - Yi Guo; Aihua Liang; Yuejun Fu (Biotechnology Letters, 2019)

Individual differences in inhibitory control abilities modulate the functional neuroplasticity of inhibitory control - Mo Chen; Yan Jing Wu; Junjie Wu; Yongben Fu; Shuhua Li; Huanhuan Liu; Chunming Lu; Taomei Guo (Brain Structure and Function, 2019)

Effect of freeze-thaw cycles on uniaxial mechanical properties of cohesive coarse-grained soils - Yong-long Qu; Guo-liang Chen; Fu-jun Niu; Wan-kui Ni; Yan-hu Mu; Jing Luo (Journal of Mountain Science, 2019)

Metabolomics reveals the drought-tolerance mechanism in wild soybean (Glycine soja) - Xiaoxia Wang; Rui Guo; Mingxia Li; Yuan Liu; Mingli Zhao; Hui Fu; Xueying Liu; Shiyao Wang; Lianxuan Shi (Acta Physiologiae Plantarum, 2019)

RNA-Seq-based transcriptomic profiling of primary interstitial cells of Cajal in response to bovine viral diarrhea virus infection - Shengnan Li; Xinyan Hu; Ruixin Tian; Yanting Guo; Junzhen Chen; Zhen Li; Xinyan Zhao; Ling Kuang; Duoliang Ran; Hongqiong Zhao; Xiaohong Zhang; Jinquan Wang; et al. (Veterinary Research Communications, 2019)

Extensive changes in gene expression and alternative splicing due to homoeologous exchange in rice segmental allopolyploids - Zhibin Zhang; Tiansi Fu; Zhijian Liu; Xutong Wang; Hongwei Xun; Guo Li; Baoxu Ding; Yuzhu Dong; Xiuyun Lin; Karen A. Sanguinet; Bao Liu; Ying Wu; et al. (Theoretical and Applied Genetics, 2019)

Exponential rolling circle amplification coupled with lateral flow dipstick strips as a rapid and sensitive method for the field detection of Karlodinium veneficum - Fu Guo Liu; Guo Fu Chen; Chun Yun Zhang; Yuan Yuan Wang; Jin Zhou (Journal of Applied Phycology, 2019)

Role of Pigment Epithelium-Derived Factor in Arsenic-Induced Vascular Endothelial Dysfunction in a Rat Model - Xiangnan Guo; Xiaoyan Fu; Xiaona Liu; Jingqiu Wang; Zhongzhe Li; Lin Gao; Yuanyuan Li; Wei Zhang (Biological Trace Element Research, 2019)

Evaluation of the association between urinary cadmium levels below threshold limits and the risk of diabetes mellitus: a dose-response meta-analysis - Fei-Fei Guo; Zhi-Yong Hu; Bing-Yan Li; Li-Qiang Qin; Chunling Fu; Huifang Yu; Zeng-Li Zhang (Environmental Science and Pollution Research, 2019)

Changes of non-protein thiols in root and organic acids in xylem sap involved in cadmium translocation of cadmium-safe rice line (Oryza Sative L.) - Qin Li; Jingyi Guo; Xizhou Zhang; Haiying Yu; Fu Huang; Lu Zhang; Man Zhang; Tingxuan Li (Plant and Soil, 2019)

Identification of the pathogens causing konjac dry rot in China - Jinping Wu; Jie Zhou; Zhenbiao Jiao; Jiaping Fu; Fengling Guo (Journal of Plant Diseases and Protection, 2019)

Assessment of lake eutrophication recovery: the filtering trajectory method (FTM) and its application to Dianchi Lake, China - Jian Zhao; Guo Fu (Environmental Monitoring and Assessment, 2019)

Characterization of a novel victorivirus isolated from the phytopathogenic fungus Botryosphaeria dothidea - Mengmeng Yang; Lifeng Zhai; Feng Xiao; Yashuang Guo; Min Fu; Ni Hong; Guoping Wang (Archives of Virology, 2019)

Mitochondrial Gene Heterogeneity and Population Genetics of Haemaphysalis longicornis (Acari: Ixodidae) in China - Zhong-Bo Li; Yi-Tian Fu; Tian-Yin Cheng; Guo-Min Yao; Qiang-Hong Hou; Fen Li; Yu Zhao; Feng-Cai Zou; Guo-Hua Liu (Acta Parasitologica, 2019)

Dynamic Response of Offshore Open-Ended Pile under Lateral Cyclic Loadings - Junwei Liu; Zhen Guo; Na Zhu; Hui Zhao; Ankit Garg; Longfei Xu; Tao Liu; Changchun Fu (Journal of Marine Science and Engineering, 2019)
Foundations for offshore wind turbines (OWTs) are mainly open-ended piles that are subjected to cyclic loadings caused by winds, waves and currents. This study aims to investigate the dynamic responses of open-ended pipe pile under lateral cyclic loadings, as well as the characteristics of the soil plug and surrounding soil. Both large-scale indoor model test and discrete element simulation were adopted in this study. The test results show that the resistance of each part of the pipe pile increases linearly with depth during the process of pile driving. The pile side resistance degradation effect was also observed along with the friction fatigue. The soil plug formation rate decreases gradually with an increase in the pile depth. The influence range in the surrounding soil is about 5~6 times of the pile diameter. The cumulative displacement of the pile head increases with the number of cycles. Lateral tangential stiffness and lateral ultimate bearing capacity decreases with an increase in number of cycles. The severe disturbance range of soil around the pile is 2~3 times of the pile diameter. The center of rotation of the pile body is about 0.8 times of the pile body depth. The side frictional resistance and lateral pressure of the pile body is found to fluctuate along the pile body. Additionally, the lateral pressure and side friction resistance decreases gradually with decreasing tendency of the former more than the latter.

First report of lettuce big-vein associated varicosavirus infecting lettuce in China - Guo-Hua Zheng; Ting Ye; Fu-Rong Liao; Wen-Zhu Zhang; Yan-Lin Ming (Journal of Plant Pathology, 2019)