Design strategies of perovskite nanofibers electrocatalysts for water splitting: A mini review - Yaobin Wang; Yan Jiang; Yunxia Zhao; Xinlei Ge; Qian Lu; Ting Zhang; Dongsheng Xie; Meng Li; Yunfei Bu (Chemical Engineering Journal, 2023)

Realizing high thermoelectric performance in magnetic field-assisted solution synthesized nanoporous SnSe integrated with quantum dots - Shuang Li; Yunxiang Hou; Shihua Zhang; Yaru Gong; Suniya Siddique; Di Li; Jun Fang; Pengfei Nan; Binghui Ge; Guodong Tang (Chemical Engineering Journal, 2023)

Inhibition of human and rat placental 3β-hydroxysteroid dehydrogenase/Δ5,4-isomerase activities by insecticides and fungicides: Mode action by docking analysis - Jingjing Li; Fuhong Tian; Yunbing Tang; Lei Shi; Shaowei Wang; Zhiyan Hu; Yang Zhu; Yiyan Wang; Huitao Li; Ren-shan Ge; Xiaoheng Li (Chemico-Biological Interactions, 2023)

Experimental study on a phase change cooling garment to improve thermal comfort of factory workers - Haiying Wang; Zan Xu; Baowei Ge; Jiankai Li (Building and Environment, 2023)

Coenzyme self-sufficiency system-recent advances in microbial production of high-value chemical phenyllactic acid - Tinglan Li; Zhao Qin; Dan Wang; Xue Xia; Xiaojie Zhou; Ge Hu (World Journal of Microbiology and Biotechnology, 2023)

Positional cloning identified HvTUBULIN8 as the candidate gene for round lateral spikelet (RLS) in barley (Hordeum vulgare L.) - Dandan Qin; Gang Liu; Rui Liu; Chunchao Wang; Fuchao Xu; Qing Xu; Yu Ling; Guoqing Dong; Yanchun Peng; Shuangtao Ge; Ganggang Guo; Jing Dong; et al. (Theoretical and Applied Genetics, 2023)
Key message Map-based cloning, subcellular localization, virus-induced-gene-silencing and transcriptomic analysis reveal HvTUB8 as a candidate gene with pleiotropic effects on barley spike and leaf development via ethylene and chlorophyll metabolism. Abstract Barley lateral spikelet morphology and grain shape play key roles in grain physical quality and yield. Several genes and QTLs for these traits have been cloned or fine mapped previously. Here, we report the phenotypic and genotypic analysis of a barley mutant with round lateral spikelet (rls) from cv. Edamai 934. rls had round lateral spikelet, short but round grain, shortened awn, thick glume and dark green leaves. Histocytologic and ultrastructural analysis revealed that the difference of grain shape of rls was caused by change of cell arrangement in glume, and the dark leaf color resulted from enlarged chloroplast. HvTUBULIN8 ( HvTUB8 ) was identified as the candidate gene for rls by combination of RNA-Seq, map-based-cloning, virus-induced-gene-silencing (VIGS) and protein subcellular location. A single G-A substitution at the third exon of HvTUB8 resulted in change of Cysteine 354 to tyrosine. Furthermore, the mutant isoform Hvtub8 could be detected in both nucleus and cytoplasm, whereas the wild-type protein was only in cytoplasm and granular organelles of wheat protoplasts. Being consistent with the rare phenotype, the “A” allele of HvTUB8 was only detected in rls , but not in a worldwide barley germplasm panel with 400 accessions. VIGS confirmed that HvTUB8 was essential to maintain spike integrity. RNA-Seq results suggested that HvTUB8 may control spike morphogenesis via ethylene homeostasis and signaling, and control leaf color through chlorophyll metabolism. Collectively, our results support HvTUB8 as a candidate gene for barley spike and leaf morphology and provide insight of a novel mechanism of it in barley development.

Effects of waterlogging and elevated salinity on the allocation of photosynthetic carbon in estuarine tidal marsh: a mesocosm experiment - Ya-Lei Li; Zhen-Ming Ge; Li-Na Xie; Shi-Hua Li; Li-Shan Tan; Kasper Hancke (Plant and Soil, 2023)

Risk assessment methods of cascade reservoir dams: a review and reflection - Te Wang; Zongkun Li; Wei Ge; Yadong Zhang; Yutie Jiao; Hua Zhang; Heqiang Sun; Pieter van Gelder (Natural Hazards, 2023)

Roles of microRNAs and exosomes in Helicobacter pylori associated gastric cancer - Xiao-Han Xu; Shu-Li Shao; Dong Guo; Li-Na Ge; Zan Wang; Peng Liu; Yuan-Yong Tao (Molecular Biology Reports, 2023)

Precursors to large rockslides visible on optical remote-sensing images and their implications for landslide early detection - Weile Li; Weiwei Zhan; Huiyan Lu; Qiang Xu; Xiangjun Pei; Dong Wang; Runqiu Huang; Daqing Ge (Landslides, 2023)

Temporal change of plankton size structure preserved by Lugol’s solution: a FlowCAM study - Zijia Liu; Yuan Dong; Qian P. Li; Zhengchao Wu; Zaiming Ge; Mengzhen Ma (Journal of Oceanology and Limnology, 2023)

Associations and burdens of relative humidity with cause-specific mortality in three Chinese cities - Yayuan Mei; Ang Li; Meiduo Zhao; Jing Xu; Runkui Li; Jiaxin Zhao; Quan Zhou; Xiaoyu Ge; Qun Xu (Environmental Science and Pollution Research, 2023)

Driving effects and transfer prediction of heavy metal(loid)s in contaminated courtyard gardens using redundancy analysis and multilayer perceptron - Huijuan Hao; Panpan Li; Yuanyuan Li; Yuntao Lv; Wanming Chen; Jianjun Xu; Dabing Ge (Environmental Monitoring and Assessment, 2023)

A Time-course Transcriptional Kinetics of Genes in Behavior, Cortisol Synthesis and Neurodevelopment in Zebrafish Larvae Exposed to Imidacloprid and Thiamethoxam - Jin-Ge Zhang; Dong-Dong Ma; Si-Ying Li; Xiao-Bing Long; Fang Liu; Zhi-Jie Lu; Wen-Jun Shi (Bulletin of Environmental Contamination and Toxicology, 2023)

Aberrant Topological Properties of Brain Functional Network in Children with Obstructive Sleep Apnea Derived from Resting-State fMRI - Tingting Ji; Xuemin Ren; Ting Long; Xiaodan Li; Lin Mei; Wentong Ge; Jie Zhang; Shengcai Wang; Yongli Guo; Zhifei Xu; Yun Peng; Jiangang Liu; et al. (Brain Topography, 2023)

Characteristics analysis and prediction of Low Earth Orbit (LEO) satellite clock corrections by using least-squares harmonic estimation - Haibo Ge; Tianhao Wu; Bofeng Li (GPS Solutions, 2023)

Discrepant impact of polyethylene microplastics on methane emissions from different paddy soils - Zihan Zhang; Zhihan Yang; Hongwen Yue; Mouliang Xiao; Tida Ge; Yaying Li; Yongxiang Yu; Huaiying Yao (Applied Soil Ecology, 2023)

Evaluating the effects of contact time and leaching solution on measured solubilities of aerosol trace metals - Rui Li; Shuwei Dong; Chengpeng Huang; Feng Yu; Fu Wang; Xiaofei Li; Huanhuan Zhang; Yan Ren; Mingxian Guo; Qingcai Chen; Baozhu Ge; Mingjin Tang (Applied Geochemistry, 2023)

Comparison of pulsed-field gel electrophoresis and a novel amplified intergenic locus polymorphism method for molecular typing of Campylobacter jejuni - Jin-Hong Liu; Cheng-Lu Lan; Ge-Feng Yao; Nian-Qing Kong; Yong-Wen Luo; Chu-Yi Li; Shui-Lian Bi (Archives of Microbiology, 2023)

Evaluation of housekeeping genes as references for quantitative real‐time PCR analysis of European eel, Anguilla anguilla - Ying‐Ying Li; Xi Chen; Jin‐Xian Yang; Qiang Chen; Tie‐Ying Song; Jun‐Qing Ge (Journal of Fish Biology, 2023)
Eels are important aquaculture species for which an increasing number of reference genes are being identified and applied. In this study, five housekeeping genes [RPL7 (ribosomal protein L7), 18 S (18 S ribosomal RNA), EF1A (elongation factor 1α), ACTB (β‐actin) and GAPDH (glyceraldehyde‐3‐phosphate dehydrogenase)] were chosen to evaluate their reliability as reference genes for quantitative real‐time PCR (qPCR) for the study of Anguilla anguilla . The expression of the selected genes in different eel tissues was determined using qPCR at different growth stages or upon challenge by Anguillid herpesvirus (AngHV), and the expression levels of these genes were then compared and evaluated using the geNorm and NormFinder algorithms. Then, RefFinder was used to comprehensively rank the examined housekeeping genes. Interestingly, the expression of the evaluated housekeeping genes exhibited tissue‐dependent and treatment‐dependent variations. In different growth periods A. anguilla tissues, the most stable genes were the following: ACTB in mucus; 18 S in skin and kidney; RPL7 in muscle, gill, intestine and brain; EF1A in heart and liver; and GAPDH in spleen. In contrast, in AngHV‐challenged A. anguilla tissues, the most stable genes were the following: 18 S in mucus; RPL7 in skin, gill, heart, spleen, kidney and intestine; EF1A in muscle and liver; and ACTB in brain. Further comparison analysis indicated that the expression of RPL7 and EF1A was stable in multiple A. anguilla tissues in different growth periods and in eels challenged by AngHV. Nonetheless, the expression level of GAPDH in eel tissues was lower, and it was unstable in several tissues. These results indicated that the selection of reference genes for qPCR analysis in A. anguilla should be made in accordance with experimental parameters, and both RPL7 and EF1A could be used as reference genes for qPCR study of A. anguilla at different growth stages or upon challenge by AngHV. The reference genes identified in this study could improve the accuracy of qPCR data and facilitate further studies aimed at understanding the biology of eels.

Darwin's naturalization conundrum reconciled by changes of species interactions - Jiang Wang; Shao‐Peng Li; Yuan Ge; Xiao‐Yan Wang; Song Gao; Tong Chen; Fei‐Hai Yu (Ecology, 2023)
Although phylogenetic distance between native and exotic species has a close link with their interactions, it is still unclear how environmental stresses and species interactions influence the relationship between phylogenetic distance and biological invasions. Here we assessed the effect of invader–native phylogenetic distance on the growth of the invader ( Symphyotrichum subulatum ) under three levels of drought (no, moderate, or intense drought). Under no drought, interspecific competition between close relatives was the dominant process and native communities more closely related to the invader showed higher resistance to invasion, supporting Darwin's naturalization hypothesis. In contrast, under intense drought, facilitation between close relatives by mutualism with arbuscular mycorrhizal fungi (AMF) became more important, and the invader became more successful in their more closely related native communities, supporting the preadaptation hypothesis. The colonization rate of AMF of the invader was higher in more closely related native communities regardless of the drought treatment, but it was only positively related to invader biomass under intense drought. Therefore, the shift of species interactions from competition to facilitation may be ascribed to the promotion of AMF to invasion occurring under intense drought, which leads to the effect of closely related natives on the invader shifting from negative to positive. Our results provide a new angle to resolve Darwin's naturalization conundrum from the change of species interactions along a stress gradient, and provide important clues for invasion management when species interactions change in response to global climatic change.

Molecular Mechanisms of Bismuth-containing Drugs Against Helicobacter pylori: a Further Update - Jiahui Liu; Xinhang Li; Yulin Zhu; Ruiguang Ge (Current Pharmacology Reports, 2022)

An offshore subsurface thermal structure inversion method by coupling ensemble learning and tide model for the South Yellow Sea - Fangjie Yu; Fengzhi Sun; Jianchao Li; Ge Chen (Frontiers in Marine Science, 2022)
The South Yellow Sea Cold Water Mass (SYSCWM), which occurs in the South Yellow Sea (SYS) during summer, significantly impacts the hydrological characteristics and marine ecosystems but lacks fine interior data. With satellite observations, significant achievements have been made in reconstructing high-resolution ocean subsurface thermohaline structure based on machine learning. However, the accuracy of offshore subsurface parameter estimation will be affected due to the macro-tidal environment and fewer in situ observations. In this paper, we coupled the TPXO tide model and Light Gradient Boosting Machine algorithm to develop an inversion model of offshore subsurface thermal structure for the SYS using sea surface data and in situ observations. After light modelling, the subsurface temperature structure in the SYS is retrieved from sea surface parameters with a spatial resolution of 0.25° at depths of 0-55 m. Observation-based dataset (ARMOR3D) and in situ observations are used for model evaluation. According to the validation of the mooring buoy observations, the overall coefficient of determination (R 2 ), which determines the percentage of variance in the dependent variable that can be explained by the independent variable, is more than 0.95. Furthermore, the R 2 is improved by 12% due to coupling tide model below the thermocline during the maturity stage of SYSCWM, which is helpful for a better reconstruction of SYSCWM. Comparing with the cruise data, the average R 2 of the proposed model is 0.927 which is slightly better than the accuracy of the observation-based ARMOR3D dataset. Since the R 2 exceeds 0.8 in the most area of 121°E~123.5°E, 33°N~36°N, the reconstruction is reliable in this area. The method provides a new explorable direction for reconstructing the ocean thermal structure in offshore areas.

Mitochondrial DNA mutation affects the pluripotency of embryonic stem cells with metabolism modulation - Juntao Qi; Qi Long; Yang Yuan; Yanshuang Zhou; Jian Zhang; Zifeng Ruan; Liang Yang; Yi Wu; Ge Xiang; Wei Li; Hao Wu; Shiwei Du; et al. (Genome Instability & Disease, 2022)

The signal-to-cutoff ratios to predict HCV infection among people who inject drugs - Bing Chen; Ling-yu Gao; Zhong-hui Ma; Hao Chang; Li-jian Pei; Qiang Zhou; Wen-ge Xing (VirusDisease, 2022)

Transplantation of Nasal Olfactory Mucosa Mesenchymal Stem Cells Benefits Alzheimer’s Disease - Chun-Gu Hong; Meng-Lu Chen; Ran Duan; Xin Wang; Zhi-Lin Pang; Li-Te Ge; Ming Lu; Hui Xie; Zheng-Zhao Liu (Molecular Neurobiology, 2022)

Inhibition of Spinal 5-HT3 Receptor and Spinal Dorsal Horn Neuronal Excitability Alleviates Hyperalgesia in a Rat Model of Parkinson’s Disease - Cheng-Jie Li; Li-Ge Zhang; Lu-Bing Liu; Meng-Qi An; Li-guo Dong; Han-Ying Gu; Yong-Ping Dai; Fen Wang; Cheng-Jie Mao; Chun-Feng Liu (Molecular Neurobiology, 2022)

Self-assembling Bioadhesive Inspired by the Fourth Repetitive Sequence of Balanus albicostatus Cement Protein 20 kDa (Balcp-20 k) - Li Jia; Yabiao Yu; Jinyang Zheng; Hao Zhou; Qiang Liu; Wei Wang; Xinxin Liu; Xiuming Zhang; Dongtao Ge; Wei Shi; Yanan Sun (Marine Biotechnology, 2022)

Enhance energy supply of largemouth bass (Micropterus salmoides) in gills during acute hypoxia exposure - Qiao Liu; Hong Wang; Jiayu Ge; Jie Luo; Kuo He; Haoxiao Yan; Xin Zhang; Rabia Tahir; Wei Luo; Zhiqiong Li; Song Yang; Liulan Zhao (Fish Physiology and Biochemistry, 2022)

Genomic Analysis and Molecular Characteristics in Carbapenem-Resistant Klebsiella pneumoniae Strains - Suying Zhao; Xingyi Qiu; Yiting Tan; Min Xu; Xiaotong Xu; Yulai Ge; Huiling Cao; Min Li; Yuxin Lin; Zhan Zhang; Lei Li; Qian Wu (Current Microbiology, 2022)

Interannual shift of tropical high cloud diurnal cycle under global warming - Zhenquan Wang; Jinming Ge; Jialin Yan; Wenxue Li; Xuan Yang; Meihua Wang; Xiaoyu Hu (Climate Dynamics, 2022)

Land use and land cover changes in coastal and inland wetlands cause soil carbon and nitrogen loss - Lishan Tan; Zhenming Ge; Yuhuang Ji; Derrick Y. F. Lai; Stijn Temmerman; Shihua Li; Xiuzhen Li; Jianwu Tang (Global Ecology and Biogeography, 2022)
Aim Natural wetlands are widely considered important for mitigation of climate change, but they have been impacted by land use and land cover change (LULCC), often resulting in ecosystem degradation and significant changes in soil carbon (C) and nitrogen (N) dynamics. However, the impact of various LULCC types on wetland soil C and N dynamics remains unclear. Location Global. Time period 1982–2021. Major taxa studied Wetland. Methods We present a global meta‐analysis using a database of 487 sites compiled from the literature, demonstrating the response of soil C and N concentrations and stocks in coastal wetlands, riparian wetlands and peatlands to various types of LULCCs, including agricultural lands, drained wetlands, aquaculture ponds, pastures and constructed wetlands. Results The conversion of coastal wetlands, riparian wetlands and peatlands to most LULCC types decreased the mean soil C and N concentrations and stocks by 17.8 ± 10.3, 25.3 ± 13.4 and 23.2 ± 6.3%, respectively. The loss of wetland soil C owing to LULCC is estimated to cause a potential CO 2 emission of 1.8–22.8 Mg CO 2 equivalent emission/ha/year, except for conversion to constructed wetlands. The soil C and N contents were more sensitive to LULCCs, relative to the stocks. We also found that the patterns of soil C and N variations were closely related to the conversion time since completion of LULCC. After LULCC, the response of soil C and N variables was sensitive to changes in plant biomass, soil water conditions, bulk density, pH and NH 4 + ‐N concentration, with the major controlling factors varying with the conversion age. Main conclusions Our results highlight the important role of LULCC in triggering soil C and N loss in natural wetlands, which enhances the greenhouse effect. As such, our study calls for sustainable land management strategies aiming at wetland conservation as a powerful tool to mitigate climate warming.

The Responses of the Ovary and Eyestalk in Exopalaemon carinicauda under Low Salinity Stress - Xiuhong Zhang; Jiajia Wang; Chengwei Wang; Wenyang Li; Qianqian Ge; Zhen Qin; Jian Li; Jitao Li (Fishes, 2022)
As a euryhaline shrimp, the ridgetail white prawn Exopalaemon carinicauda is strongly adaptable to salinity. Exploring the effect of long-term low salinity stress on ovarian development in E. carinicauda is essential to promote its culture in a non-marine environment. In this study, we performed biochemical assays and ovary histology analysis, finding that the E. carinicauda can adapt to low salinity stress through osmotic adjustment, and there was no substantial damage to the ovary of E. carinicauda under low salinity stress. Then, the ovarian development of E. carinicauda under low salt stress was further explored by RNA sequencing of eyestalk and ovarian tissues. A total of 389 differentially expressed genes (DEGs) in ovary tissue were identified under low salinity stress, and the 16 important DEGs were associated with ovarian development. The majority of the DEGs were enriched in ECM-receptor interaction, folate biosynthesis, arginine biosynthesis, insect hormone biosynthesis and lysosome which were involved in the ovarian development of E. carinicauda. A total of 1223 DEGs were identified in eyestalk tissue under low salinity stress, and the 18 important DEGs were associated with ovarian development. KEGG enrichment analysis found that ECM-receptor interaction, folate biosynthesis, lysosome, arginine biosynthesis and retinol metabolism may be involved in the ovarian development under low salinity stress. Our results provided new insights and revealed new genes and pathways involved in ovarian development of E. carinicauda under long-term low salinity stress.

Development of a pressure-retaining separation and transfer system for sediment and overlying seawater - Jin Guo; Qixiao Zhou; Yongqiang Ge; Haonan Li; Qiaoling Gao; Ying Wang; Yuan Lin; Jiawang Chen (Frontiers in Marine Science, 2022)
Methane leakage at the interface between sediment and overlying seawater is an important basis for gas hydrate exploration. Therefore, a transfer device with working pressure of 30MPa and corresponding scheme are proposed to separate and transfer the sediment and overlying water inside the sampler under the condition of pressure-retaining. Based on the pressure relief valve with adjustable threshold pressure, the device transfers the overlying water by compressing the internal volume and transfers the sediment by secondary sampling. The performance of transfer device is studied by simulation and experiment. Based on the coupled Eulerian-Lagrangian approach in the Abaqus, the secondary sampling was investigated, and the penetration resistance and coring rate of the secondary sampling tube are 141N and 86.2%, respectively. By using the hydraulic simulation software AMESim, the pressure fluctuation caused by the movement of the mechanism during the transfer process was studied, and the pressure fluctuation amplitude is within 0.89 MPa. Furthermore, the laboratory transfer tests were carried out under high pressure conditions, and meantime, the simulation results are verified. Under the working condition of 30MPa, the device can maintain a pressure loss of no more than 8.0% (2.4MPa) within two hours, maintain pressure fluctuations during the transfer process within 4.8% (1.44MPa), and ensure that the pressure in the culture kettle decreases by 4.7% relative to the pressure in the sampler after the transfer, which shows the feasibility of the device application.

Nitrogen occurrence forms and bacterial community in sediment influenced by Bellamya purificata bioturbation - Yiyun Zhang; Yiran Hou; Rui Jia; Bing Li; Jian Zhu; Xianping Ge (Frontiers in Marine Science, 2022)
Endogenous water pollution and excessive nitrogen in ponds have always been prominent problems threatening aquaculture. To solve this problem, a 70-day indoor simulation experiment was conducted. The snail Bellamya purificata was stocked at four different densities: 0, 15, 30, and 60 individuals/tank, represented as CON (control), LD (low density), MD (medium density), and HD (high density), respectively, to investigate the effects of B. purificata on the nitrogen occurrence forms and bacterial communities in the sediment. At the end of the experiment, the nitrate concentration was significantly higher, while the total nitrogen content was significantly lower in the MD group than in the other three groups. Ammonia monooxygenase activity was significantly lower in the CON group than in the other three groups, and hydroxylamine oxidase activity was significantly higher in the HD group than in the other three groups. The CON and MD groups showed the highest and lowest values in nitrate reductase activity, respectively. The hydroxylamine reductase activity decreased significantly with increasing density. Through 16S ribosomal RNA (rRNA) high-throughput sequencing, significantly affected bacterial communities by B. purificata were found. Alpha diversity results showed that, a significantly lower Shannon index was observed in the MD group than in the other three groups. The LD and MD groups showed the highest and lowest Chao1 index values, respectively. Phyla Nitrospinae and family Nitrosomonadaceae were significantly enriched in the HD and MD groups, respectively. Redundancy analysis (RDA) indicated a significant correlation between differential bacterial taxa and TN content. Predicted functional analysis based on FAPROTAX (Functional annotation of prokaryotic taxa) database showed that functional groups aerobic ammonia oxidation and aerobic nitrite oxidation were significantly enriched in the MD group. Overall, B. purificata significantly altered the bacterial community composition, increased hydroxylamine oxidase and ammonia monooxygenase activities, enhanced the bacterial nitrification process, and promoted the transformation of total nitrogen to nitrate. Moreover, B. purificata stocked at 30 and 60 individuals/tank appeared to have a significant promotion effect on the bacterial community and nitrogen occurrence forms in the sediment. Hence, co-culturing B. purificata may be a feasible and effective ecological restoration method to alleviate excess nitrogen and reduce water eutrophication.

Association of soft drink and 100% fruit juice consumption with all-cause mortality, cardiovascular diseases mortality, and cancer mortality: A systematic review and dose-response meta-analysis of prospective cohort studies - Bei Pan; Long Ge; Honghao Lai; Qi Wang; Qi Wang; Qian Zhang; Min Yin; Sheng Li; Jinhui Tian; Kehu Yang; Jiancheng Wang (Critical Reviews in Food Science and Nutrition, 2022)

Overlapping-calibration of wide-swath altimeter baseline errors using two satellites formation flying design - Chunyong Ma; Xuan Wang; Zhanwen Gao; Zheng Li; Chaofang Zhao; Ge Chen (Frontiers in Marine Science, 2022)
The sea surface height (SSH) measured by future wide-swath altimetry satellites contains observation error due to baseline measurement, which is called SSH_Error_Baseline. It is a huge challenge for satellite engineering to maintain such high accuracies of the baseline roll and length in orbit to ensure that the SSH_Error_Baseline can be maintained below 1 cm. Therefore, how to effectively reduce the SSH_Error_Baseline is extremely important. In order to solve the existing problem, an innovative overlapping-calibration method is proposed based on two-satellite formation flight design with overlapping swath. In this study, the differences of SSH data observed by these two satellites in the overlapping area is so small that it can be ignored, and the SSH_Error_Baseline dominates the difference. Then, the baseline parameters of the two satellites can be well estimated by adopting an optimal inverse method. A total of 9 groups of observing system simulation experiments (OSSEs) have been carried out, and they respectively indicate different pessimistic theoretical scenarios of baseline measurement systems. According to the results, this design can effectively reduce the SSH_Error_Baseline in most scenarios. Regarding the advantage of this method, it can be applied to all along-track observation data without requiring the application of additional auxiliary data (i.e. model data, SSH derived from nadir altimetry). Therefore, when two wide-swath altimetry satellites are simultaneously designed, the formation flight scheme proposed in this paper is recommended, especially when the measurements of the baseline cannot meet the expected accuracies.

Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression - Qin Jin; Xiaoyu Yang; Shixue Gou; Xiaoyi Liu; Zhenpeng Zhuang; Yanhui Liang; Hui Shi; Jiayuan Huang; Han Wu; Yu Zhao; Zhen Ouyang; Quanjun Zhang; et al. (Science China Life Sciences, 2022)

The DRD2 Taq1A polymorphism moderates the effect of PTSD symptom severity on the left hippocampal CA3 volume: a pilot study - Minlan Yuan; Hongru Zhu; Yuchen Li; Fenfen Ge; Su Lui; Qiyong Gong; Changjian Qiu; Huan Song; Wei Zhang (Psychopharmacology, 2022)
Rationale and objectives The hippocampus, especially the CA1, CA3, and dentate gyrus (DG) subfields, is reported to be associated with post-traumatic stress disorder (PTSD) after trauma. However, neuroimaging studies of the associations between PTSD and hippocampal subfield volumes have failed to yield consistent findings. The aim of this study is to examine whether the dopamine D2 receptor (DRD2) Taq1A polymorphism, which is associated with both hippocampal function and PTSD, moderated the association between PTSD severity and hippocampal CA1, CA3 and DG volumes. Methods T1-weighted images were acquired from 142 trauma survivors from the 2008 Wenchuan earthquake using a 3.0-T magnetic resonance imaging system. Hippocampal subfield segmentations were performed with FreeSurfer v6.0. We used the simple moderation model from the PROCESS v3.4 tool for SPSS 23.0 to examine the association between the rs1800497 polymorphism, PTSD severity, and hippocampal CA3 and DG volumes. Results A significant genotype × PTSD symptom severity interaction was found for the left CA3 volume (Δ F = 5.01, p = 0.008, Δ R 2 = 0.05). Post hoc, exploratory analyses deconstructing the interaction revealed that severe PTSD symptomatology were associated with reduced left CA3 volume among TC heterozygotes ( t = − 2.86, p = 0.005). Conclusions This study suggests that DRD2 Taq1A polymorphism moderates the association between PTSD symptomatology and left CA3 volume, which promotes an etiological understanding of the hippocampal atrophy at the subfield level. This highlights the complex effect of environmental stress, and provides possible mechanism for the relationship between the dopaminergic system and hippocampal function in PTSD.

Comparative genomic investigation of TCP gene family in eggplant (Solanum melongena L.) and expression analysis under divergent treatments - Dalu Li; Xin Tang; Yanxiao Dong; Yingying Wang; Suli Shi; Shaohang Li; Yang Liu; Haiyan Ge; Huoying Chen (Plant Cell Reports, 2022)

Comprehensive comparison of the prognostic value of systemic inflammation biomarkers for cancer cachexia: a multicenter prospective study - Hailun Xie; Guotian Ruan; Lishuang Wei; Heyang Zhang; Yizhong Ge; Qi Zhang; Shiqi Lin; Mengmeng Song; Xi Zhang; Xiaoyue Liu; Ming Yang; Meng Tang; et al. (Inflammation Research, 2022)

Obesity aggravated hippocampal-dependent cognitive impairment after sleeve gastrectomy in C57/BL6J mice via SIRT1/CREB/BDNF pathway - Yuanyuan Ma; Yelong Ji; Li Xu; Zheng Li; Shengjin Ge (Experimental Brain Research, 2022)

Effects of biochar application on the loss characteristics of Cd from acidic soil under simulated rainfall conditions - Zaijian Yuan; Yueyan Song; Dingqiang Li; Bin Huang; Yunhui Chen; Xiaojun Ge; Mingguo Zheng; Yishan Liao; Zhenyue Xie (Environmental Science and Pollution Research, 2022)

Effect of gravel content on the detachment of colluvial deposits in Benggang - Li-ting Zhang; Fang Shuai; Li-bo Chen; Yan-he Huang; Jin-shi Lin; Yue Zhang; Hong-li Ge; Fang-shi Jiang (Journal of Mountain Science, 2022)

Cerebellar injury induced by cadmium via disrupting the heat-shock response - Shao-Shuai Bi; Milton Talukder; Xue-Tong Sun; Mei-Wei Lv; Jing Ge; Cong Zhang; Jin-Long Li (Environmental Science and Pollution Research, 2022)

Two new alkaloids from Tibetan medicine of Hypecoum leptocarpum - Bo Sun; Israa Assani; Chun-Gu Wang; Mu-Xuan Wang; Ling-Fei Liu; Yan Li; Ge Yan; Yun-Ruo Yang; Zhi Chen; Zhi-Xin Liao (Natural Product Research, 2022)

Two new chemical constituents from Lonicera japonica - Jian-liang Geng; Hai-bo Li; Wen-jun Liu; Zhen-zhong Wang; Wen Ge; Wei Xiao (Natural Product Research, 2022)

Long-term response of an estuarine ecosystem to drastic nutrients changes in the Changjiang River during the last 59 years: A modeling perspective - Shenyang Shi; Yi Xu; Weiqi Li; Jianzhong Ge (Frontiers in Marine Science, 2022)
The riverine nutrient inputs to the ocean reflects land-use changes and can affect the health of coastal environments over time, especially for a highly-anthropogenically influenced river-estuary-shelf system. To investigate the impact of riverine inputs on the Changjiang Estuary ecosystem at a multi-decadal time scale where long-term observations are limited, we built a three-dimensional physics-biogeochemistry-coupled model system based on the Finite-Volume Community Ocean Model (FVCOM) and the European Regional Shelf Ecosystem Model (ERSEM). Our model successfully simulated the temporal and spatial nutrient variabilities in the river-estuary-shelf con7tinuum from 1960 to 2018. The results showed increasing trends of nitrate and phosphate and fluctuating silicate variability, thereby leading to rising nitrogen (N) to phosphorus (P) ratios and decreasing silicon (Si) to N and P ratios. Such changes in the stoichiometric relationship of nutrient species also alter the community structure of the primary producers in estuaries. Our model showed a general increase of diatoms over the 59 years, corresponding to decreased proportions of micro-phytoplankton and pico- phytoplankton. With different backgrounds of light and nutrient limitations in the river and inner shelf, our model suggests that the trend of the diatom proportion in the light-limited river mouth is more associated with silicate variability, with decreased diatom proportions occurring in the 2000s. Our model relates the hydroclimate, nutrient load, and biogeochemical cycling, reproducing estuarine ecosystem variability and clarifying issues such as the causality of the ecosystem interactions.

Nutritional Components, Biochemical Characteristics, Enzyme Activities, and Growth Differences of Five Freshwater Fish Species? - Xiaona Jiang; Yan Li; Jingwen Tian; Chitao Li; Yanlong Ge; Xuesong Hu; Lei Cheng; Xiaodan Shi; Lianyu Shi; Zhiying Jia (Fishes, 2022)
Common carp (Cyprinus carpio) is an economically important fish worldwide, with many of its species bred for consumption. However, there are few reports on the comprehensive comparative analysis of the muscle nutritional quality and stress resistance characteristics of different common carp species. In this study, after 15 months of feeding in the same environment, the nutritional components, serum biochemical indices, liver antioxidant and intestinal digestive enzyme activities, and muscle growth-related gene expression were determined in Songpu mirror carp (SPM; Cyprinus carpio Songpumirror), Heilongjiang wild carp (HLJ; Cyprinus carpio haematopirus), cold-resistant strain of purse red carp (CPR; Cyprinus carpio ‘Red purse cold-resistant’), Songhe carp (SH; Cyprinus carpio ‘Songhe’), and Songpu carp (SP; Cyprinus carpio Songpu). Muscle nutrient composition showed that HLJ had a significantly lower crude fat content and higher docosahexaenoic acid (DHA) + eicosapentaenoic acid (EPA) proportion than the other four common carp species (p

Numerical and Experimental Research on Rectification Measures for a Contraction Diversion Pier in a Pumping Station - Wentao Xu; Li Cheng; Kailian Du; Lei Yu; Yi Ge; Jiali Zhang (Journal of Marine Science and Engineering, 2022)
In order to improve the flow state of a forebay, a contraction diversion pier is discovered, the geometric parameters of which affect the improvement of the flow state. In this paper, the standard k-ε model in the computational fluid dynamics (CFD) numerical simulation method is used to research the flow state improvement of the forebay with a contraction diversion pier. In our research, the single factor method is used to analyze the influence of different geometric parameters. Then, the optimal geometric parameters of the contraction diversion pier are given. Results show that the contraction diversion pier can be used to concentrate the water flow. In the area where reflux is formed, the contraction diversion guides water flow along the diversion pier wall. In particular, when the retractable diversion pier is located in the middle of a reflux zone, the water backflow is effectively reduced, the flow state is improved, and the inlet condition of the pump is optimized. By comparing the cross-sectional streamlines, the velocity contour, the normal velocity uniformity of the longitudinal section, and the normal weighted mean angle, the optimal geometric parameters of the contraction diversion pier are obtained as follows: the distance from the contraction pier to the inlet sump is 0.1 L, the contraction angle is 20°, and the length of pier is 0.3 L.

Numerical study on crack propagation of rock mass using the time sequence controlled and notched blasting method - Xinping Li; Mingnan Xu; Yang Wang; Gang Wang; Junhong Huang; Weisong Yin; Ge Yan (European Journal of Environmental and Civil Engineering, 2022)

Rapid continuous photoflow synthesis of naturally occurring arylnaphthalene lignans and their analogs - Xiang Ge; Haowen Jiang; Jinlong Li (Natural Product Research, 2022)

Transposon insertions within alleles of BnaFT.A2 are associated with seasonal crop type in rapeseed - Qingdong Jin; Gengdong Gao; Chaocheng Guo; Taihua Yang; Ge Li; Jurong Song; Na Zheng; Shuai Yin; Licong Yi; Zhen Li; Xianhong Ge; Graham J. King; et al. (Theoretical and Applied Genetics, 2022)

Protective Effect of Levilactobacillus brevis Against Yersinia enterocolitica Infection in Mouse Model via Regulating MAPK and NF-κB Pathway - Ziqi Shi; Naiyu Guan; Weijiao Sun; Tianzhi Sun; Lingdi Niu; Jinyu Li; Junwei Ge (Probiotics and Antimicrobial Proteins, 2022)

Rootstock rescues watermelon from Fusarium wilt disease by shaping protective root-associated microbiomes and metabolites in continuous cropping soils - An-Hui Ge; Zhi-Huai Liang; Li-Li Han; Ji-Ling Xiao; Yi Zhang; Qing Zeng; Ji-Fang Xiang; Chao Xiong; Li-Mei Zhang (Plant and Soil, 2022)

Cadmium Through Disturbing MTF1-Mediated Metal Response Induced Cerebellar Injury - Shao-Shuai Bi; Milton Talukder; Hai-Tao Jin; Mei-Wei Lv; Jing Ge; Cong Zhang; Jin-Long Li (Neurotoxicity Research, 2022)

The Location Reliability of the Resting-State fMRI FC of Emotional Regions Towards rTMS Therapy - Na Zhao; Juan Yue; Zi-Jian Feng; Yang Qiao; Qiu Ge; Li-Xia Yuan; Jue Wang; Yu-Tao Xiang; Yu-Feng Zang (Neuroinformatics, 2022)

Intensive management of a bamboo forest significantly enhanced soil nutrient concentrations but decreased soil microbial biomass and enzyme activity: a long-term chronosequence study - Yihan Yao; Shanzhi Cao; Xueliu Gong; Bhupinder Pal Singh; Yunying Fang; Tida Ge; Hailong Wang; Yongfu Li (Journal of Soils and Sediments, 2022)

Genotyping USDA rice (Oryza spp.) mini-core collection with functional markers for important agronomic traits - Kehu Li; Lily Yan Wang; Huanhuan Ren; Yongyi Ge (Genetic Resources and Crop Evolution, 2022)

Evaluation of the water pollution risk of dam and dike-break floods in the inundated area - Yadong Zhang; Zongkun Li; Wei Ge; Jianyou Wang; Xinyan Guo; Te Wang; Hua Zhang (Environmental Science and Pollution Research, 2022)

Protective Effects of Astilbin Against Cadmium-Induced Apoptosis in Chicken Kidneys via Endoplasmic Reticulum Stress Signaling Pathway - Xiuyu Li; Ming Ge; Weifeng Zhu; Panpan Wang; Jiangfeng Wang; Tiange Tai; Yuxi Wang; Jianxu Sun; Guangliang Shi (Biological Trace Element Research, 2022)

How Frequently Will the Persistent Heavy Rainfall over the Middle and Lower Yangtze River Basin in Summer 2020 Happen under Global Warming? - Zi-An Ge; Lin Chen; Tim Li; Lu Wang (Advances in Atmospheric Sciences, 2022)

Transport Patterns and Potential Sources of Atmospheric Pollution during the XXIV Olympic Winter Games Period - Yuting Zhang; Xiaole Pan; Yu Tian; Hang Liu; Xueshun Chen; Baozhu Ge; Zhe Wang; Xiao Tang; Shandong Lei; Weijie Yao; Yuanzhe Ren; Yongli Tian; et al. (Advances in Atmospheric Sciences, 2022)
The attainment of suitable ambient air quality standards is a matter of great concern for successfully hosting the XXIV Olympic Winter Games (OWG). Transport patterns and potential sources of pollutants in Zhangjiakou (ZJK) were investigated using pollutant monitoring datasets and a dispersion model. The PM 2.5 concentration during February in ZJK has increased slightly (28%) from 2018 to 2021, mostly owing to the shift of main potential source regions of west-central Inner Mongolia and Mongolian areas (2015–18) to the North China Plain and northern Shanxi Province (NCPS) after 2018. Using CO as an indicator, the relative contributions of the different regions to the receptor site (ZJK) were evaluated based on the source-receptor-relationship method (SRR) and an emission inventory. We found that the relative contribution of pollutants from NCPS increased from 33% to 68% during 2019–21. Central Inner Mongolia (CIM) also has an important impact on ZJK under unfavorable weather conditions. This study demonstrated that the effect of pollution control measures in the NCPS and CIM should be strengthened to ensure that the air quality meets the standard during the XXIV OWG.

Adaptive biomineralization in two morphotypes of Sternaspidae (Annelida) from the Northern China Seas - Meiling Ge; Jing Mo; Jack Chi-Ho Ip; Yixuan Li; Wenge Shi; Zongling Wang; Xuelei Zhang; Qinzeng Xu (Frontiers in Marine Science, 2022)
Polychaetes are segmented annelid worms that play a key role in biomineralization in modern oceans. However, little is known about the underlying processes and evolutionary mechanisms. The ventro-caudal shield of Sternaspidae is a typical phosphate biomineral in annelids. Here, we investigated two sternaspids from the northern China Seas, Sternaspis chinensis and Sternaspis liui syn. n, which evolved diverse shield characteristics as local adaptation. Genetic distances, phylogenetic analyses of nuclear markers ( 18S and 28S genes), and mitochondrial genomes revealed that the latter is a junior synonym of the former. The integration of elemental composition and the transcriptomic analysis provided insights into phenotypic shield differences. The electron probe microanalysis showed that shields in S. chinensis were more biomineralized (i.e., with higher iron, phosphorus, and calcium contents) than those in S. liui syn. n. Transcriptomes of the body wall around shields determined 17,751 differentially expressed genes (DEGs) in two morphotypes of the synonymous species. Function enrichment analysis of DEGs showed that S. chinensis has an enrichment of the putative biomineralization pathways (i.e., ion transport and calmodulin binding), while S. liui syn. n consumed more energy and produced more proteins (i.e., oxidative phosphorylation and ribosome). DEGs allowed to identify seven shell matrix proteins expressed differentially in the two morphotypes, especially calponin, filamin, chitinase, and protease inhibitor BPTI/kunitz, which might contribute to shield evolutionary plasticity response to their living habitats. Overall, this study 1) revealed an environmental biomineralization adaptation in two polychaete morphotypes of one species by integrating shield chemical composition of shields and transcriptome analyses and 2) provided insights into the molecular mechanisms underlying polychaete biomineralization.

From ambiguity to transparency: influence of environmental information disclosure on financial performance in the context of internationalization - Ge Wang; Qi’ang Du; Xiaodong Li; Xiaopeng Deng; Yanliang Niu (Environmental Science and Pollution Research, 2022)

Genome-wide association study reveals that GhTRL1 and GhPIN8 affect cotton root development - Ziqian Cui; Shaodong Liu; Changwei Ge; Qian Shen; Siping Zhang; Huijuan Ma; Ruihua Liu; Xinhua Zhao; Ruida Liu; Pengzhen Li; Hongchen Wang; Qidi Wu; et al. (Theoretical and Applied Genetics, 2022)

Twin peaks of in-hospital mortality among patients with STEMI across five phases of COVID-19 outbreak in China: a nation-wide study - Jianping Li; Nan Zhang; Ziyi Zhou; Xiao Huang; Weiyi Fang; Hongbing Yan; Jiyan Chen; Weimin Wang; Dingcheng Xiang; Xi Su; Bo Yu; Yan Wang; et al. (Science China Life Sciences, 2022)

Pathological Networks Involving Dysmorphic Neurons in Type II Focal Cortical Dysplasia - Yijie Shao; Qianqian Ge; Jiachao Yang; Mi Wang; Yu Zhou; Jin-Xin Guo; Mengyue Zhu; Jiachen Shi; Yiqi Hu; Li Shen; Zhong Chen; Xiao-Ming Li; et al. (Neuroscience Bulletin, 2022)

Phylogenetic analyses, morphological studies, and muscarine detection reveal two new toxic Pseudosperma (Inocybaceae, Agaricales) species from tropical China - Li-Na Zhao; Wen-Jie Yu; Lun-Sha Deng; Jian-Hua Hu; Yu-Peng Ge; Nian-Kai Zeng; Yu-Guang Fan (Mycological Progress, 2022)

Triphenylpyrazoline ketone chlorophenols as potential candidate compounds against Parkinson’s disease: design, synthesis, and biological evaluation - Ning Ning Cheng; Le Hua Zhang; Rui Ge; Xiu E. Feng; Qing Shan Li (Medicinal Chemistry Research, 2022)

Detection of Pyrophosphate and Alkaline Phosphatase Activity Based on PolyT Single Stranded DNA - Copper Nanoclusters - Liu Yao; Xin Li; Hong Li; Zhibin Liao; Chuchu Xie; Ge Ning; Yaohui Wu; Yonghong Wang (Journal of Fluorescence, 2022)

WRKY74 regulates cadmium tolerance through glutathione-dependent pathway in wheat - Ge-Zi Li; Yong-Xing Zheng; Hai-Tao Liu; Jin Liu; Guo-Zhang Kang (Environmental Science and Pollution Research, 2022)

Phthalate exposure enhances incidence of urinary incontinence: US NHANES, 2003–2004 and 2005–2006 - Xianyanling Yi; Kun Jin; Shi Qiu; Xingyu Xiong; Tianyi Zhang; Ge Peng; Dazhou Liao; Xiaonan Zheng; Hang Xu; Hong Li; Lu Yang; Qiang Wei; et al. (Environmental Science and Pollution Research, 2022)

Geochemical characteristics, genetic types, and controlling factors of natural gas in Jiyang Depression, Bohai Bay Basin (eastern China) - Tianchen Ge; Xiangchun Chang; Yuan Zhuang; Xiaojun Li (Frontiers of Earth Science, 2022)

Spatial variation in bacterial community and dissolved organic matter composition in groundwater near a eutrophic lake - Ning Ma; Li Gao; Yan Zhang; Zhengkui Ge; En Hu; Baozhu Pan; Jian Wang; Ming Li (Aquatic Ecology, 2022)

Synchronized Motion-Based UAV–USV Cooperative Autonomous Landing - Wenzhan Li; Yuan Ge; Zhihong Guan; Gang Ye (Journal of Marine Science and Engineering, 2022)
A synchronous motion-based control strategy for unmanned aerial vehicle (UAV) landing on an unmanned surface vehicle (USV) is proposed to address the problem of low accuracy or even failure of UAV landing on the surface of a USV under wave action. Firstly, the landing marks are identified and localized based on computer vision; secondly, the USV attitude angle is predicted based on a bidirectional long-short term memory (Bi-LSTM) neural network to ensure that the UAV can respond to USV attitude changes in real-time; furthermore, the UAV attitude controller is designed based on a PID algorithm to realize UAV–USV synchronous motion. The experimental results demonstrate that the proposed UAV–USV synchronous motion landing scheme with high landing accuracy is more suitable for the UAV to achieve autonomous landing on a USV in a complex marine environment.

Research Progress on Volatile Organic Compounds Emissions from Coal-fired Power Plants - Jingxin Xu; Fahua Zhu; Xinlei Ge; Haiwei Li; Xiuyong Zhao; Wenxin Tian; Xi Zhang; Yuan Bai; Fengxia An; Sheng Wang (Current Pollution Reports, 2022)

Production and cytology of Brassica autoallohexaploids with two and four copies of two subgenomes - Bowei Cai; Tai Wang; Fang Yue; Arrashid Harun; Bin Zhu; Wei Qian; Xianhong Ge; Zaiyun Li (Theoretical and Applied Genetics, 2022)

A strategy for establishing an efficient somatic embryo regeneration system in Castanea mollissima Blume - Xiao-wei Li; Zhi-lin Sun; Yue-rong Gao; Jing-yi Ge; Yu-zhen Tian; Bing Liu; Shi-kan Sun; Ke-feng Fang; Ling Qin; Qing-qin Cao (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Causal Effect of Genetically Determined Blood Copper Concentrations on Multiple Diseases: A Mendelian Randomization and Phenome-Wide Association Study - Xiuming Feng; Wenjun Yang; Lulu Huang; Hong Cheng; Xiaoting Ge; Gaohui Zan; Yanli Tan; Lili Xiao; Chaoqun Liu; Xing Chen; Zengnan Mo; Longman Li; et al. (Phenomics, 2022)

Precise ages of gold mineralization and pre-gold hydrothermal activity in the Baiyun gold deposit, northeastern China: in situ U–Pb dating of hydrothermal xenotime and rutile - Haoxuan Feng; Ping Shen; Rixiang Zhu; Jian-Wei Zi; David I. Groves; Changhao Li; Yang Wu; Ge Ma; Taiyang Li (Mineralium Deposita, 2022)

Feed types affect the growth, nutrient utilization, digestive capabilities, and endocrine functions of Megalobrama amblycephala: a comparative study between pelleted and extruded feed - Chao-Fan He; Xiang-Fei Li; Guang-Zhen Jiang; Ling Zhang; Miao Sun; Ya-Ping Ge; Wei-Liang Chen; Wen-Bin Liu (Fish Physiology and Biochemistry, 2022)

The application of sulfate radical-based advanced oxidation processes in hydrothermal treatment of activated sludge at different stages: A comparative study - Yang Yu; Panpan Li; Bingxing Zhu; Ye Liu; Ran Yu; Shifu Ge (Environmental Science and Pollution Research, 2022)

Probabilistic health risk assessment for residents exposed to potentially toxic elements near typical mining areas in China - Huijuan Hao; Panpan Li; Yuntao Lv; Wanming Chen; Dabing Ge (Environmental Science and Pollution Research, 2022)

The preparation of slow-release fertilizers with biomass ash and water/waste acid solutions from desulfurization and denitrification of flue gas - Yongfeng Qi; Ziqian Wang; Panle Ge; Meiting Wang; Chuanling Zhang; Huawei Wang; Lingzhi Zhao; Jiang Wu; Yan Li (Environmental Science and Pollution Research, 2022)

Boosting the green total factor energy efficiency in urban China: Does low-carbon city policy matter? - Da Gao; Yi Li; Ge Li (Environmental Science and Pollution Research, 2022)

FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells - Fangfang Zhao; Fangfang Ge; Minghua Xie; Zhenyu Li; Chunbao Zang; Lingsuo Kong; Youguang Pu; Xucai Zheng; Yiao Tan (Clinical & Experimental Metastasis, 2022)
N 6 -methyladenosine (m 6 A) is the most prevalent and internal modification that occurs in the messenger RNAs of eukaryotes. However, knowledge of the impact of these modifications on gene expression regulation remains limited. By using the in vitro MeRIP-seq and RNA-seq assays, we discovered that the mRNA demethylase FTO was significantly up-regulated in esophageal squamous cell carcinoma (ESCC) tissues and cells. Knockdown of FTO drastically suppressed the proliferation, migration, and invasion of ESCC cells. Furthermore, by using transcriptome-wide m 6 A-seq and RNA-seq assays, we identified ERBB2 is the target of FTO, which acts in concert in ESCC tumorigenesis and metastasis. Moreover, loss and gain functional studies suggested that the m 6 A reader YTHDF1 stabilizes ERBB2 mRNA via decoding the m 6 A modification. All these results uncovered a new signaling cascade, including FTO, YTHDF1, and ERBB2, which finely regulates the ESCC progression.

PRMT6/LMNA/CXCL12 signaling pathway regulated the osteo/odontogenic differentiation ability in dental stem cells isolated from apical papilla - Ning Wang; Miao Li; Yangyang Cao; Haoqing Yang; Le Li; Lihua Ge; Zhipeng Fan; Chen Zhang; Luyuan Jin (Cell and Tissue Research, 2022)

Inhibition of AoAur1 increases mycelial growth, hyphal fusion and improves physiological adaptation to high-temperature stress in Aspergillus oryzae - Jinxin Ge; Zhe Zhang; Yuan Li; Zhihong Hu; Bin He; Yongkai Li; Bin Zeng; Chunmiao Jiang (Archives of Microbiology, 2022)

The Synergism between Methanogens and Methanotrophs and the Nature of their Contributions to the Seasonal Variation of Methane Fluxes in a Wetland: The Case of Dajiuhu Subalpine Peatland - Luwen Wang; Jiwen Ge; Liang Feng; Yaoyao Liu; Yu Li; Jiumei Wang; Xiang Xiao; Zhiqi Zhang (Advances in Atmospheric Sciences, 2022)

Full-Length Transcriptome Sequencing and Comparative Transcriptomic Analysis Provide Insights Into the Ovarian Maturation of Exopalaemon carinicauda - Jiajia Wang; Jitao Li; Qianqian Ge; Wenyang Li; Jian Li (Frontiers in Marine Science, 2022)
The ridgetail white shrimp Exopalaemon carinicauda has the potential to be used as a useful experimental organism in the field of crustacean research due to its transparent body, large egg, and short reproductive cycle. However, little is known about the regulatory mechanisms of ovarian maturation in E. carinicauda . In this study, we applied PacBio single-molecule long-read sequencing technology to unveil the whole transcriptome landscape of Exopalaemon carinicauda to better understand the molecular mechanisms of ovarian development. A total of 49.05 G polymerase read bases were generated, finally, 15, 151 unigenes were successfully identified with a mean length of 4, 257 bp and an N50 of 4, 884 bp from ovary tissues (five different ovarian developmental stages). A total of 14, 007 unigenes were successfully annotated in at least one public database. In addition, 8, 861 coding sequences, 4, 594 lncRNAs and 895 transcription factors were identified. Furthermore, we performed RNA-Seq analysis combined with Iso-Seq results to investigate ovarian maturation regulation mechanism and validated the results by quantitative real-time PCR. We annotated five vitellogenin isoforms in the full-length transcriptome, meanwhile these five genes and vitellogenin receptor suggested an important role during previtellogenesis of E. carinicauda . Genes were involved in PI3K-Akt signaling pathway, retinol metabolism, cell cycle and hedgehog signaling pathway, which showed obvious associations with ovarian maturation of E. carinicauda. We identified 40 DEGs, such as forkhead box protein L2, which may be related to ovarian development in the comparisons. The expression profiles of genes such as ecdysone receptor, ecdysone-induced protein 74EF, ecdysone inducible gene E75 and post-molt protein suggest that they were significantly associated with reproductive molting in the ovarian mature stage. In conclusion, the present study identified important genes and pathways involved in ovarian maturation, which might be useful for studying the reproductive regulation and mechanisms of ovarian maturation in E. carinicauda .

Formation and Breakdown of an Offshore Summer Cold-Water Zone and Its Effect on Phytoplankton - Weiqi Li; Xiangqian Zhou; Jianzhong Ge; Pingxing Ding; Dongyan Liu (Frontiers in Marine Science, 2022)
Estuarine plume frontal zones typically form a vertical two-layer structure with low-salinity and a high-temperature plume during the summertime. However, two field surveys in the Changjiang River Estuary and its adjacent shelf waters identified a significant surface cold-water zone (CWZ) formation in the summers of 2014 and 2015. The sea surface temperature of the CWZ was 4°C lower than the multi-year summer average. Satellite images showed that the CWZ mainly appeared in the Yangtze Shoal during the periods of July 1–17, 2014, and July 3–19, 2015. A three-dimensional physical-biogeochemical coupled model was used to explore the formation mechanism of the CWZ. Our investigation revealed that an uncharacteristic northerly wind during the southerly monsoon resulted in a significant onshore retreat of the plume front. Vertical tidal mixing is stronger than the decreased stratification in the former plume-covered region, which resulted in the formation of the CWZ. This process was accompanied by relatively lower net heat flux, which also promoted CWZ formation. The formation of CWZ had a strong ecological impact; enhanced vertical mixing transported nutrients from the lower layer to the surface column, relaxing the CWZ’s phosphate limitation. CWZ formation also increased the depth of the mixed layer and turbidity level in the water column, forming a temporary light limitation in the center. At the margin of the CWZ, it formed a patch with a high concentration of chlorophyll a . The underwater light was sufficient once the plume was restored and the CWZ was stratified again, and the phytoplankton grew rapidly in the center of the CWZ.

Development of a quantitative risk assessment method for a biomass gasification unit by combining DEMATEL-ISM and CM-TOPSIS - Jishuo Li; Kaili Xu; Ji Ge; Bingjie Fan (Stochastic Environmental Research and Risk Assessment, 2022)

OsAPL controls the nutrient transport systems in the leaf of rice (Oryza sativa L.) - Zhen Yan; Man-Yu Yang; Biligen-Gaowa Zhao; Guo Li; Qing Chao; Feng Tian; Ge Gao; Bai-Chen Wang (Planta, 2022)

Further Develop 1,3,4-Thiadiazole Based Probe to Effectively Detect 2,4,6-Trinitrophenol with the Help of DFT Calculations - Xuejiao Li; Yanxin Hu; Weijie Huang; Weiran Li; Ge Gao; Chengwei Lü; Yue An (Journal of Fluorescence, 2022)

Production and Evaluation of a Novel Multi-Epitope Bivalent Vaccine Against Echinococcus multilocaularis Metacestode - Runle Li; Mingyuan Xin; Kunmei Liu; Bingwen Hu; Jingwei Ma; Pei Zhou; Lin Feng; Mingquan Pang; Ri-li Ge; Haining Fan; Le Guo; Feng Tang (International Journal of Peptide Research and Therapeutics, 2022)

Convolutional neural network-based applied research on the enrichment of heavy metals in the soil–rice system in China - Panpan Li; Huijuan Hao; Xiaoguang Mao; Jianjun Xu; Yuntao Lv; Wanming Chen; Dabing Ge; Zhuo Zhang (Environmental Science and Pollution Research, 2022)

An efficient method for undifferenced BDS-2/BDS-3 high-rate clock estimation - Xinyun Cao; Kaifa Kuang; Yulong Ge; Fei Shen; Shoujian Zhang; Jiancheng Li (GPS Solutions, 2022)

Zircon and monazite U-Pb ages of the Mashan Complex of the Jiamusi Block of NE China: a link to Gondwana? - Maohui Ge; Zhuang Li; Long Li; Jinjiang Zhang; Kai Liu (International Geology Review, 2022)

Cytotoxic tigliane diterpenoids from Euphorbia neorubella - Shuangcheng Chen; Nga Yi Tsang; Haowen Jiang; Hongjie Zhang; Xiang Ge; Yanni Wu; Yu Shen; Wenxia Xie; Jinlong Li (Natural Product Research, 2022)

Cu/Fe Bimetallic Modified Fly Ash: An Economical Adsorbent for Enhanced Phosphorus Removal from Aqueous Solutions - Wenshu Ge; Shuangqing Li; Minqiang Jiang; Gaohong He; Wenjun Zhang (Water, Air, & Soil Pollution, 2022)

Sex determination mechanisms and sex control approaches in aquaculture animals - Xi-Yin Li; Jie Mei; Chu-Tian Ge; Xiao-Li Liu; Jian-Fang Gui (Science China Life Sciences, 2022)

Dynamic changes of reactive oxygen species in paddy overlying water: mechanisms and implications - Shaochong Liu; Mengxi Tan; Danyu Huang; Dixiang Wang; Mengyuan Geng; Jialin Wen; Changyin Zhu; Liqiang Ge; Ning Chen; Yan Gao; Jiangye Li; Jianbin Pan; et al. (Journal of Soils and Sediments, 2022)

Towards economic value-added growth without carbon emission embodied growth in North–North trade—An empirical analysis of US-German trade - Rongrong Li; Shuting Ge (Environmental Science and Pollution Research, 2022)

The impact of TOPBP1 mutations in human cancers on the DNA damage response - Zhenzhen Yan; Xiuling Ge; Jiaxu Wang; Feng Xu; Mengyao Li; Xiuhua Liu; Xiaochun Yu; Chen Wu (Genome Instability & Disease, 2022)

Influence analysis of blasting on adjacent high-rise buildings for deep rock excavations in urban area: a case study - Pengfei Li; Chenhe Ge; Liangwu Zhu; Mingju Zhang; Jiaxing Jia; Jingshu Xu (Arabian Journal of Geosciences, 2022)

Recent advances in the structure, synthesis, and applications of natural polymeric hydrogels - Khalid Gul; Ren-You Gan; Cui-Xia Sun; Ge Jiao; Ding-Tao Wu; Hua-Bin Li; Ahmad Kenaan; Harold Corke; Ya-Peng Fang (Critical Reviews in Food Science and Nutrition, 2022)

Diel Vertical Distribution of Mesozooplankton Functional Groups in the North Pacific Subtropical Gyre: A Case Study - Ruping Ge; Yixuan Li; Hongju Chen; Facan Lei; Yunyun Zhuang; Guangxing Liu (Frontiers in Marine Science, 2022)
Understanding the diel vertical migration (DVM) patterns of zooplankton has important implications for biological pumping and pelagic food webs. The functional traits of zooplankton generally determine their distribution in the environment. However, knowledge about the DVM patterns of zooplankton with different functional traits is limited. Here, we used a trait-based approach to study the vertical distributions of zooplankton in the North Pacific Subtropical Gyre (NPSG). Four functional traits, namely, body length, feeding type, trophic group, and reproductive mode, were selected in this study. A high biodiversity of zooplankton (165 taxa) was recorded in the NPSG. Zooplankton was mainly concentrated above 100 m and exhibited normal DVM. Zooplankton with small and medium body sizes (<2 mm, 69% ± 16%), current feeding (43% ± 14%), and omnivore–herbivores (54% ± 14%) were dominant in the NPSG. The proportion of sac spawners in total abundance (52% ± 14%) was higher than that of broadcast spawners (48% ± 14%), which differed from that in the coastal regions. Sixteen functional groups of zooplankton were identified. Different functional groups exhibited distinct DVM patterns due to the influence of different factors. The DVM patterns of current-feeding omnivore–herbivores were significantly correlated with chlorophyll a , whereas giant ambush-feeding carnivores exhibited normal DVM patterns and were substantially correlated with the vertical distribution of their food organisms. However, the small omnivore–carnivores showed reverse DVM patterns. Overall, this study provided a new perspective for studies on zooplankton DVM from the aspect of functional traits.

Characterization and mutagenesis of a novel Mycobacterium smegmatis-derived glutamate decarboxylase active at neutral pH - Yudi Li; Guiying Chen; Fanglan Ge; Ting Dang; Yao Ren; Bei Zeng; Wei Li (World Journal of Microbiology and Biotechnology, 2022)

Mapping and characterization of the Rx3 gene for resistance to Xanthomonas euvesicatoria pv. euvesicatoria race T1 in tomato - Ge Meng; Yao Xiao; Aitong Li; Zilin Qian; Yinge Xie; Luyao Yang; Huabing Lin; Wencai Yang (Theoretical and Applied Genetics, 2022)

Nanosecond pulsed electric fields prime mesenchymal stem cells to peptide ghrelin and enhance chondrogenesis and osteochondral defect repair in vivo - Kejia Li; Litong Fan; Jianjing Lin; Boon Chin Heng; Zhantao Deng; Qiujian Zheng; Jue Zhang; Yangzi Jiang; Zigang Ge (Science China Life Sciences, 2022)

Identification and management of GCK-MODY complicating pregnancy in Chinese patients with gestational diabetes - Yanyan Jiang; Fusong Jiang; Ming Li; Qingkai Wu; Chenming Xu; Rong Zhang; Mingqiang Song; Yanzhong Wang; Ying Wang; Yating Chen; Juan Zhang; Xiaoxu Ge; et al. (Molecular and Cellular Biochemistry, 2022)

Synthesis, antibacterial evaluation and in silico study of DOTA-fluoroquinolone derivatives - Weitian Li; Ge Hong; Lina Mao; Zengping Xu; Jiawen Wang; Wenzhi Wang; Tianjun Liu (Medicinal Chemistry Research, 2022)

An attention-constrained neural network with overall cognition for landslide spatial prediction - Ruilong Wei; Chengming Ye; Yonggang Ge; Yao Li (Landslides, 2022)

Extracellular vesicles-associated tRNA-derived fragments (tRFs): biogenesis, biological functions, and their role as potential biomarkers in human diseases - Qiuyan Weng; Yao Wang; Yaoyao Xie; Xiuchong Yu; Shuangshuang Zhang; Jiaxin Ge; Zhe Li; Guoliang Ye; Junming Guo (Journal of Molecular Medicine, 2022)
Traditionally, transfer RNAs (tRNAs) specifically decoded messenger RNA (mRNA) and participated in protein translation. tRNA-derived fragments (tRFs), also known as tRNA-derived small RNAs (tsRNAs), are generated by the specific cleavage of pre- and mature tRNAs and are a class of newly defined functional small non-coding RNAs (sncRNAs). Following the different cleavage positions of precursor or mature tRNA, tRFs are classified into seven types, 5′-tRNA half, 3′-tRNA half, tRF-1, 5′U-tRF, 3′-tRF, 5′-tRF, and i-tRF. It has been demonstrated that tRFs have a diverse range of biological functions in cellular processes, which include inhibiting protein translation, modulating stress response, regulating gene expression, and involvement in cell cycles and epigenetic inheritance. Emerging evidences have indicated that tRFs in extracellular vesicles (EVs) seem to act as regulatory molecules in various cellular processes and play essential roles in cell-to-cell communication. Furthermore, the dysregulation of EV-associated tRFs has been associated with the occurrence and progression of a variety of cancers and they can serve as novel potential biomarkers for cancer diagnosis. In this review, the biogenesis and classification of tRFs are summarized, and the biological functions of EV-associated tRFs and their roles as potential biomarkers in human diseases are discussed.

Evaluating crop coefficient and associated processes in a drip irrigation with different color of biodegradable film mulching - Ning Chen; Xianyue Li; Haibin Shi; Qi Hu; Yuehong Zhang; Qin’ge Dong; Guoshuai Wang (Irrigation Science, 2022)

Analysis of the heavy metals (As, Pb, Cu, Zn) by leaching and sequential extraction procedure from a municipal solid waste incinerator fly ash co-processing cement kiln plant - Nan Yang; Zhimeng Ge; Aihong Li; Baiyong Wei; Yinming Li; Ye Zhang; Qianjin Shen; Tuqiang Wang; Xueqian Wu; Xiangdong Cao; Jianping Guo; Zhaojia Wang (Environmental Monitoring and Assessment, 2022)

Environmental drivers of soil microbial activity and diversity along an elevational gradient - Si-li Peng; Zhi-wei Ge; Gang-cai Liu; Ling-feng Mao (Journal of Mountain Science, 2022)

Altered diversity and functioning of soil and root-associated microbiomes by an invasive native plant - Siyu Li; Dong Xie; Xiaogai Ge; Wei Dong; Junwei Luan (Plant and Soil, 2022)

Genetic variation and association mapping of phenolic, flavonoid content and antioxidant capacity in USDA rice mini-core collection - Kehu Li; Qingzhu Li; Lily Yan Wang; Huanhuan Ren; Yongyi Ge (Genetic Resources and Crop Evolution, 2022)

Does foreign private investment affect the clean industrial environment? Nexus among foreign private investment, CO2 emissions, energy consumption, trade openness, and sustainable economic growth - Mina Ge; Desti Kannaiah; Junrong Li; Nasir Khan; Malik Shahzad Shabbir; Kanwal Bilal; Mosab I. Tabash (Environmental Science and Pollution Research, 2022)

Does FDI improve green total factor energy efficiency under heterogeneous environmental regulation? Evidence from China - Da Gao; Ge Li; Yi Li; Kexin Gao (Environmental Science and Pollution Research, 2022)

Modeling wide-area tropospheric delay corrections for fast PPP ambiguity resolution - Bobin Cui; Jungang Wang; Pan Li; Maorong Ge; Harald Schuh (GPS Solutions, 2022)
The performance of precise point positioning (PPP) has been significantly improved thanks to the continuous improvements in satellite orbit, clock, and ambiguity resolution (AR) technologies, but the convergence speed remains a limiting factor in real-time PPP applications. To improve the PPP precision and convergence time, tropospheric delays from a regional network can be modeled to provide precise correction for users. We focus on the precise modeling of zenith wet delay (ZWD) over a wide area with large altitude variations for improving PPP-AR. By exploiting the water vapor exponential vertical decrease, we develop a modified optimal fitting coefficients (MOFC) model based on the traditional optimal fitting coefficients (OFC) model. The proposed MOFC model provides a precision better than 1.5 cm under sparse inter-station distances over the Europe region, with a significant improvement of 70% for high-altitude stations compared to the OFC model. The MOFC model with different densities of reference stations is further evaluated in GPS and Galileo kinematic PPP-AR solutions. Compared to the PPP-AR solutions without tropospheric delay augmentation, the positioning precision of those with 100-km inter-station spacing MOFC and OFC is improved by 25.7% and 17.8%, respectively, and the corresponding time to first fix (TTFF) is improved by 36.9% and 33.0% in the high-altitude areas. On the other hand, the OFC model only slightly improves the TTFF and positioning accuracy when using the 200 km inter-station spacing modeling and even degrades the positioning for high-altitude stations, whereas using the MOFC model, the PPP-AR solutions always improve. Moreover, the positioning precision improvement of MOFC compared with OFC is about 22.1%, 21.7%, and 25.7% for the Galileo-only, GPS-only, and GPS + Galileo PPP-AR solutions, respectively.

Changes in the waterbird community of the Yangtze River in the Three Gorges Reservoir Region, China, 2003–2013 - Xiuming Li; Wenfa Xiao; Ge Sun; Tian Ma; Fuguo Liu; Xiaoyun Liu; Hualong Su; Kaijun Pan; Ruimei Cheng; Fawen Qian (Biologia, 2022)

Global divergent trends of algal blooms detected by satellite during 1982–2018 - Chong Fang; Kaishan Song; Hans W Paerl; Pierre‐Andre Jacinthe; Zhidan Wen; Ge Liu; Hui Tao; Xiaofeng Xu; Tiit Kutser; Zongming Wang; Hongtao Duan; Kun Shi; et al. (Global Change Biology, 2022)
Algal blooms (ABs) in inland lakes have caused adverse ecological effects, and health impairment of animals and humans. We used archived Landsat images to examine ABs in lakes (>1 km 2 ) around the globe over a 37‐year time span (1982–2018). Out of the 176032 lakes with area >1 km 2 detected globally, 863 were impacted by ABs, 708 had sufficiently long records to define a trend, and 66% exhibited increasing trends in frequency ratio (FRQR, ratio of the number of ABs events observed in a year in a given lake to the number of available Landsat images for that lake) or area ratio (AR, ratio of annual maximum area covered by ABs observed in a lake to the surface area of that lake), while 34% showed a decreasing trend. Across North America, an intensification of ABs severity was observed for FRQR ( p p p p

Influences of the 1855 AD Huanghe (Yellow River) Relocation on Sedimentary Organic Carbon Burial in the Southern Yellow Sea - Jianying Liu; Da-Wei Li; Yang Ding; Tiantian Ge; Weifang Chen; Chih-An Huh; Meixun Zhao (Frontiers in Marine Science, 2022)
The Huanghe (Yellow River) supplies large amount of sediments and terrestrial organic carbon (OC) to the eastern Chinese marginal seas. A relocation of the Huanghe outlet from the southern Yellow Sea (YS) to the Bohai Sea occurred in 1855 AD, however, detailed knowledge about the impact of this relocation on sedimentary source and OC burial in Chinese marginal seas is still critically lacking. In this study, we present total OC content and its isotope (δ 13 C), along with bulk total organic carbon (TOC)/total nitrogen (TN) molar ratio and lipid biomarker contents, in a sediment core HH12 from the southern YS with sediment age spanning the last 300 years. We find that TOC and terrestrial lipid biomarker mass accumulation rates were lower between 1855 AD and 1950 AD than that prior to 1855 AD in core HH12; and in accordance, both TOC/TN ratio and δ 13 C records indicate a gradual decrease of terrigenous source contributions to sedimentary OC. This suggests that the relocation of the Huanghe outlet reduced the transport of terrestrial OC to the southern YS. However, the δ 13 C record also indicates a relative increase of terrestrial OC contribution to sedimentary OC after 1950 AD, and the most likely explanation is increased contributions from the old Huanghe delta erosion and Korean rivers. Future studies should focus on better constraining the variations of terrestrial and marine endmembers with δ 13 C and Δ 14 C analyses of specific biomarkers to examine these linkages.

QTL mapping and candidate gene prediction for fiber yield and quality traits in a high-generation cotton chromosome substitution line with Gossypium barbadense segments - Quanwei Lu; Pengtao Li; Rui Yang; Xianghui Xiao; Ziyin Li; Qiuyu Wu; Juwu Gong; Qun Ge; Aiying Liu; Shengli Du; Jundi Wang; Yuzhen Shi; et al. (Molecular Genetics and Genomics, 2022)

Legacy effect of elevated CO2 and N fertilization on mineralization and retention of rice (Oryza sativa L.) rhizodeposit-C in paddy soil aggregates - Yuhong Li; Hongzhao Yuan; Anlei Chen; Mouliang Xiao; Yangwu Deng; Rongzhong Ye; Zhenke Zhu; Kazuyuki Inubushi; Jinshui Wu; Tida Ge (Soil Ecology Letters, 2022)

A highly pathogenic Marek’s disease virus isolate from chickens immunized with a bivalent vaccine in China - Huimin Li; Zengxu Ge; Qiong Luo; Qiang Fu; Ruiai Chen (Archives of Virology, 2022)

Scholte wave dispersion and particle motion mode in ocean and ocean crust - Xu Xin; Wan Yong-Ge; Li Zhen-Yue; Sheng Shu-Zhong (Applied Geophysics, 2022)

Evaluation of Allicin Against Alveolar Echinococcosis In Vitro and in a Mouse Model - Chuanchuan Liu; Haining Fan; Lu Guan; Lan Ma; Ri-li Ge (Acta Parasitologica, 2022)
Purpose At present, the chemotherapy for alveolar echinococcosis (AE) is mainly based on albendazole (ABZ). However, more than 20% of patients fail chemotherapy. Therefore, new and more effective treatments are urgently needed. Allicin has been reported to have antibacterial and antiparasitic effects. The objectives of the present study were to investigate the in vivo and in vitro efficacy of allicin against Echinococcus multilocularis ( E. multilocularis ). Methods The effects of allicin on protoscolex survival and structural changes were evaluated in vitro . The 4-week-old BALB/c male mice used for in vivo modelling underwent inoculation of E. multilocularis protoscoleces by intraperitoneal injection, followed by intragastric administration of allicin for 6 weeks. Then, the effects of allicin on lymphocyte subsets, metacestode growth and host tissue matrix metalloproteinase 2 (MMP2)/MMP9 expression around metacestodes in mice were evaluated. The toxicity of allicin was further evaluated in vivo and in vitro . Results Att 40 μg/mL, allicin showed a killing effect on protoscoleces in vitro and treatment resulted in the destruction of protoscolex structure. Molecular docking showed that allicin could form hydrogen bonds with E. multilocularis cysteine enzymes. After 6 weeks of in vivo allicin treatment, the spleen index of mice was increased and the weight of metacestodes was reduced. Allicin increased the proportion of CD4 + T cells and decreased the proportion of CD8 + T cells in the peripheral blood and spleen. Pathological analysis of the metacestodes showed structural disruption of the germinal and laminated layers after allicin treatment. In addition, allicin inhibited the expression of MMP2 and MMP9 in metacestode-surrounding host tissues. At 160 μg/mL, allicin had no significant toxicity to normal hepatocytes but could inhibit hepatoma cell proliferation. At 30 mg/kg, allicin had no significant hepatorenal toxicity in vivo . Conclusion These results suggest that allicin exerts anti- E. multilocularis effects in vitro and in vivo and can enhance immune function in mice, with the potential to be developed as a lead compound against echinococcosis.

Combined Effects of Microplastics and Benzo[a]pyrene on the Marine Diatom Chaetoceros muelleri - Yuanyuan Su; Huaiyuan Qi; Yipeng Hou; Mengyi Gao; Jie Li; Minggang Cai; Xiaoshan Zhu; Miao Chen; Chengjun Ge; Dongdong Fu; Zezheng Wang; Licheng Peng (Frontiers in Marine Science, 2022)
Microplastics are regarded as ubiquitous pollutants in the ocean and have attracted worldwide concerns. Benzo[a]pyrene (B[a]P), one of typical polycyclic aromatic hydrocarbons (PAHs), is commonly detected in marine environment. Once coexisted, the microplastics and B[a]P may interact with each other and result in combined toxicity to organisms, and these remain to be systematically elucidated. Thus, this study aims to investigate (i) the effects of single micro-sized polystyrene (mPS), polyethylene terephthalate (mPET), and B[a]P on cell growth of Chaetoceros muelleri ; and (ii) the interaction of microplastics and B[a]P, and their combined effects on C. muelleri . The results showed that both single microplastics and B[a]P at a high concentration of 150 μg/L inhibited the growth of C. muelleri . For single treatment of microplastics, stronger inhibition effects on microalgae was caused by mPET than that of mPS, with the highest IR of 25.23 and 11.17%, respectively. This may be attributed to the obvious surface roughness of mPET. By comparison, the combined effects of microplastics and B[a]P significantly inhibited the growth of C. muelleri as compared with the single treatment of B[a]P ( P < 0.05). Synergistic effect was found in the combination of microplastics with B[a]P at high concentrations of 150 μg/L. Interestingly, the antagonistic effect on C. muelleri was observed in the combined treatment of microplastics and B[a]P at low concentrations of 10 μg/L. In addition, the pollutants reduced the content of photosynthetic pigments in microalgal cells. The SOD and MDA content of microalgae increased in the early stage of exposure to pollutants (e.g., Days 1 and 5), but decreased in the later stage (Day 15) compared with the control group. The decreased superoxide dismutase (SOD) and catalase (CAT) activity in single and composite systems may indicate that the antioxidative enzymatic system of microalgae has been inhibited or destroyed. This study will be helpful to further explore the ecological threats of microplastics and PAHs to the marine ecosystem.

Identification and analysis of oil candidate genes reveals the molecular basis of cottonseed oil accumulation in Gossypium hirsutum L. - Zhibin Zhang; Juwu Gong; Zhen Zhang; Wankui Gong; Junwen Li; Yuzhen Shi; Aiying Liu; Qun Ge; Jingtao Pan; Senmiao Fan; Xiaoying Deng; Shaoqi Li; et al. (Theoretical and Applied Genetics, 2022)

Litter nitrogen concentration changes mediate effects of drought and plant species richness on litter decomposition - Jiang Wang; Yuan Ge; Johannes H. C. Cornelissen; Xiao-Yan Wang; Song Gao; Yi Bai; Tong Chen; Zhong-Wang Jing; Chong-Bang Zhang; Wen-Li Liu; Jun-Min Li; Fei-Hai Yu (Oecologia, 2022)

3D Geological Suitability Evaluation for Urban Underground Space Development Based on Combined Weighting and Improved TOPSIS - Fanfan Dou; Huaixue Xing; Xiaohui Li; Feng Yuan; Zhitang Lu; Xiangling Li; Weiya Ge (Natural Resources Research, 2022)

Analysis of volatile organic compounds in exhaled breath after radiotherapy - Dianlong Ge; Xue Zou; Yajing Chu; Jijuan Zhou; Wei Xu; Yue Liu; Qiangling Zhang; Yan Lu; Lei Xia; Aiyue Li; Chaoqun Huang; Pei Wang; et al. (Journal of Zhejiang University-SCIENCE B, 2022)

miR-361-3p mitigates hypoxia-induced cardiomyocyte injury via targeting apoptosis initiators caspase-2/-8/-9 - Jinwei Zhang; Xiankun Zhou; Jing Sun; Mingzhou Li; Jideng Ma; Liangpeng Ge (In Vitro Cellular & Developmental Biology - Animal, 2022)

Prediction and validation of cross-protective candidate antigen of Hyalomma asiaticum cathepsin L between H. asiaticum and H. anatolicum - Ruiqi Song; Xuejie Zhai; Xinli Fan; Yongchang Li; Huercha; Ting Ge; Caishan Li; Min Li; Wenwen He; Huizhen Zheng; Lu Gan; Yang Zhang; et al. (Experimental and Applied Acarology, 2022)

Dynamic environmental regulation threshold effect of technical progress on green total factor energy efficiency: evidence from China - Ge Li; Da Gao; Yi Li (Environmental Science and Pollution Research, 2022)

Peripartum cardiomyopathy: a global effort to find the cause and cure for the rare and little understood disease - Amy Li; K. Campbell; S. Lal; Y. Ge; A. Keogh; P. S. Macdonald; P. Lau; John Lai; W. A. Linke; J. Van der Velden; A. Field; B. Martinac; et al. (Biophysical Reviews, 2022)
In this review, we present our current understanding of peripartum cardiomyopathy (PPCM) based on reports of the incidence, diagnosis and current treatment options. We summarise opinions on whether PPCM is triggered by vascular and/or hormonal causes and examine the influence of comorbidities such as preeclampsia. Two articles published in 2021 strongly support the hypothesis that PPCM may be a familial disease. Using large cohorts of PPCM patients, they summarised the available genomic DNA sequence data that are expressed in human cardiomyocytes. While PPCM is considered a disease predominately affecting the left ventricle, there are data to suggest that some cases also involve right ventricular failure. Finally, we conclude that there is sufficient evidence to warrant an RNAseq investigation and that this would be most informative if performed at the cardiomyocytes level rather than analysing genomic DNA from the peripheral circulation. Given the rarity of PPCM, the combined resources of international human heart tissue biobanks have assembled 30 ventricular tissue samples from PPCM patients, and we are actively seeking to enlarge this patient base by collaborating with human heart tissue banks and research laboratories who would like to join this endeavour.

Synthesis of Silver- and Strontium-Substituted Hydroxyapatite with Combined Osteogenic and Antibacterial Activities - Yunfei Li; Wenying Wang; Jing Han; Zirui Li; Qiuxiang Wang; Xue Lin; Kun Ge; Guoqiang Zhou (Biological Trace Element Research, 2022)

Sources and intensity of CH4 production in paddy soils depend on iron oxides and microbial biomass - Yuhong Li; Zhenke Zhu; Xiaomeng Wei; Yakov Kuzyakov; Baozhen Li; Pil Joo Kim; Jinshui Wu; Shoulong Liu; Tida Ge (Biology and Fertility of Soils, 2022)

GIS-based spatial prediction of landslide using road factors and random forest for Sichuan-Tibet Highway - Cheng-ming Ye; Rui-long Wei; Yong-gang Ge; Yao Li; José Marcato Junior; Jonathan Li (Journal of Mountain Science, 2022)

Influence of El Niño decaying pace on low latitude tropical cyclogenesis over the western North Pacific - Changhao Lu; Xuyang Ge; Melinda Peng; Tim Li (International Journal of Climatology, 2022)
The modulation of El Niño decaying pace on tropical cyclones (TCs) activities at low latitude (within 10°) over the western North Pacific (WNP) is investigated in this study. During rapidly decaying El Niño events, fewer TCs occur near the equator and the averaged genesis location is more westward. More TCs are found in the southeast of WNP during slowly decaying phase of El Niño events. The distinctive differences of TC genesis frequency and their respective meridional positions are related to the modulation of El Niño to large‐scale environmental flows. Both dynamical and thermodynamical conditions, such as low‐level vorticity, mid‐level relative humidity and vertical motion, are favourable for TC genesis in the southeast of WNP during slowly decaying El Niño events. The differences of sea surface temperature, vertical wind shear, and TC heat potential between the two El Niño events are similar to the spatial distribution of TC genesis at low latitude. Disturbances in southeastern WNP in slowly decaying El Niño events are more likely to develop into TCs due to the stronger zonal convergence and meridional shear of zonal wind. These findings may help to better understand the interaction between low‐latitude TCs and El Niño. The higher frequency of low‐latitude TC genesis and their more eastward TC genesis position in slowly decaying El Niño events may in turn slow down the transition speed of El Niño.

Study on Buried Depth Protection Index of Submarine Cable Based on Physical and Numerical Modeling - Xinlong Zheng; Yongqiang Ge; Zhifei Lu; Chen Cao; Peng Zhou; Shiqiang Li; Jiawang Chen (Journal of Marine Science and Engineering, 2022)
The buried depth of submarine cables is very important to avoid damage on the cable from dropping and dragging anchors. This study focused on the actual engineering needs of submarine power cable protection and laying construction. In order to investigate the buried depth protection index of submarine cable, physical model tests, theory analysis, and numerical simulations were conducted in this study. The effects of the bottoming velocity, dropping energy, and anchor mass on the anchor penetration depth were analyzed and investigated. The analytical model based on the impact and drag mechanism is presented to analyze the forces and energy on the anchor. The accuracy and reliable of the model test results are verified by the theory analysis and numerical simulation, indicating that the buried depth protection index of the submarine cable in the research area is recommended to be 3 m. The research results can provide guidance for operation of the submarine cable laying machine and submarine cable protection.

Characterization of Mesenchymal Stem Cells Derived from Bisphosphonate-Related Osteonecrosis of the Jaw Patients’ Gingiva - Mengyu Li; Jiajia Wang; Yejia Yu; Yuqiong Zhou; Yueqi Shi; Wenjie Zhang; Geehun Son; Jing Ge; Jun Zhao; Chi Yang; Shaoyi Wang (Stem Cell Reviews and Reports, 2022)
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a clinical condition that specifically occurs in the oral cavity, characterized by retarded wound healing in oral mucosa accelerating the exposure of bone. Moreover, the pathological mechanism remains poorly understood. Gingival mesenchymal stem cells (GMSCs) play a critical role in gingival healing and soft tissue regeneration. Although previous studies have showed that bisphosphonates (BPs) are highly toxic to healthy GMSC, there is overall lack of direct evidence demonstrating the characterization of GMSCs derived from BRONJ patients. In present study, we isolated GMSCs for the first time from the central area of BRONJ patients’ gingiva (center-BRONJ GMSCs) and the peripheral area (peri-BRONJ GMSCs), and found that they exhibited decreased proliferation, adhesion, migration capacities and underwent early apoptosis in vitro compared control GMSCs. Notably, the central and peripheral BRONJ GMSCs transplantation in a mice excisional skin model also displayed lower cell survival rate and poor healing effects than that of controls. Mechanistically, TGF-β1 signaling pathway was suppressed not only in BRONJ patients’ gingival lesions but also in BRONJ GMSCs transplantation animal model. The results above suggested that under the microenvironment of BRONJ patients, the dysfunction of GMSCs and the suppressed TGF-β1 signaling pathway may be the vital factors in impaired gingival healing, thus contributing to persistent exposure of underlying bone and development of BRONJ. This study provides new insights into the prevention for BRONJ by improving the functions of GMSCs and upregulating TGF-β1 in accelerating gingival wound healing. Graphical Abstract Schematic illustration of the dysfunction of BRONJ GMSCs in vitro and BRONJ GMSCs transplantation in a mice skin model delaying cutaneous wound healing mainly via suppressing TGF-β1 signaling pathway.

Theoretical and Experimental Study on Single Spherical Button Penetration into Granite Rock Under Dynamic Impact Loading - Yanliang Li; Jianming Peng; Jiming Li; Dong Ge (Rock Mechanics and Rock Engineering, 2022)

A light-responsive transcription factor SmMYB35 enhances anthocyanin biosynthesis in eggplant (Solanum melongena L.) - Linzhi Li; Shaohang Li; Haiyan Ge; Suli Shi; Dalu Li; Yang Liu; Huoying Chen (Planta, 2022)

Organic fertilizer amendment promotes wheat resistance to herbivory and biocontrol services via bottom-up effects in agroecosystems - Shimin Gu; Myron P. Zalucki; Xingyuan Men; Jing Li; Ruixing Hou; Qingqing Zhang; Feng Ge; Fang Ouyang (Journal of Pest Science, 2022)

Metabolomics provide insights into the endogenous mechanism of strobilation in the scyphozoan jellyfish Rhopilema esculentum - Jianlong Ge; Xiaohui Chen; Changlin Liu; Jie Tan; Li Bian; Lifei Chen; Siqing Chen (Journal of Oceanology and Limnology, 2022)

Dual performance of environmental regulation on economic and environmental development: evidence from China - Chunmei Li; Abbas Ali Chandio; Ge He (Environmental Science and Pollution Research, 2022)

Assessing the impact of mechanism of green public consumption policy on environmental equity: evidence from China - Chunmei Li; Abbas Ali Chandio; Usman Farooq; Jam Ghulam Murtaza Sahito; Ge He (Environment, Development and Sustainability, 2022)
This study investigates the impact of the mechanism of green public consumption policy on environmental equity and provides a feasible reference for the rational formulation of corresponding policies for China. Establish a mediation effect model using the stepwise regression and bootstrap analysis method, this study explores the direct and indirect effects of fiscal expenditure intensity on environmental equity. The results revealed that increasing fiscal expenditure on energy conservation and environmental protection cannot directly and significantly affect environmental equity, but it has a significant indirect positive impact on environmental equality through fiscal decentralization. It is also found that the impact of green public consumption policy on environmental equity varies in the eastern, central and western parts of China. Our findings indicated that the expenditure of energy conservation and environmental protection indirectly affects environmental equity through fiscal decentralization. The willingness of the government to protect the environment regulates the impact of green public consumption policies on environmental equity. The phenomenon of feeding the east from the west of resources and environment is obvious. According to the characteristics of regional development, we should formulate energy conservation and environmental protection policies and adjust the direction of policies to promote regional environmental equity.

Astragalus Polysaccharide Protects Against Cadmium-Induced Autophagy Injury Through Reactive Oxygen Species (ROS) Pathway in Chicken Embryo Fibroblast - Xudong Shen; Zequn Tang; Yu Bai; Meishuo Wan; Miao Yu; Jingyi Chen; Guangxing Li; Ruili Zhang; Ming Ge (Biological Trace Element Research, 2022)

Species Composition and Assemblages of Ichthyoplankton in Sansha Bay, Fujian Province, China - Yan Jiang; Bai-an Lin; Hao-yang He; Guang-mao Ding; Li-ting Yan; Ge Zhang; Min Liu; Lian-ming Zheng (Frontiers in Marine Science, 2021)
Sansha Bay (26.40−27.00°N, 119.50−120.20°E) is a typical semi-enclosed bay, located in northern Fujian Province, China, and adjacent to the East China Sea. The ichthyoplankton species composition and assemblage structure were investigated based on monthly sampling at 25 stations in April−September 2019, covering the important spring and summer spawning seasons in the region. Sampling was conducted in the first 3−5 days of the full moon or new moon phases using a standard plankton net through horizontal and vertical tows during daytime. In total, 25,819 ichthyoplankton samples were collected, of which 25,449 samples (i.e., 24,757 eggs and 692 larvae) were from horizontal tows. For horizontal tow samples, the ichthyoplankton were classified into 58 taxa in 15 orders and 23 families with a combination of external morphology and DNA barcoding analyses, from pelagic to demersal and benthic species. The dominant order was the Gobiiformes, including 23 species (39.7% of all species). The dominant taxa, in terms of relative abundance and frequency of occurrence, consisted of commercially important fishes, such as Setipinna tenuifilis (Valenciennes, 1848) (Engraulidae), Epinephelus akaara (Temminck and Schlegel, 1842) (Serraenidae), Collichthys lucidus (Richardson, 1844), Nibea albiflora (Richardson, 1846) (Sciaenidae), Acanthopagrus schlegelii (Bleeker, 1854), and Pagrus major (Temminck and Schlegel, 1843) (Sparidae), accounting for 78.9% of the horizontal tow samples. Low-valued and small-sized fishes, such as Stolephorus commersonnii Lacepède, 1803 (Engraulidae), Solea ovata Richardson, 1846 (Soleidae), Nuchequula nuchalis (Temminck and Schlegel, 1845), and Photopectoralis bindus (Valenciennes, 1835) (Leiognathidae), were also dominant species, accounting for 11.4% of the horizontal tow samples. The ichthyoplankton assemblage was categorized into five different temporal assemblages based on the cluster and nonmetric multidimensional scaling analysis, namely, April, May, June, July, and August−September (ANOSIM, Global R = 0.656, p < 0.01) with the highest density and richness of ichthyoplankton occurred in May. The spatial distribution pattern showed that the high density (ind./m 3 ) of ichthyoplankton occurred mainly in S12–S25 in Guanjingyang and along the Dongchong Peninsula coastline into Dongwuyang, while low density occurred mainly in S01–S11 in the northwest waters of Sandu Island (ANOVA, F = 8.270, p < 0.05). Temperature, salinity, and chlorophyll a were key factors structuring the ichthyoplankton assemblages in Sansha Bay. In addition, this study revealed the changes of the ichthyoplankton composition, density, and spatial distribution in Sansha Bay over the past three decades.

A Systematic Study on Berthing Capacity Assessment of Sanya Yazhou Fishing Port by Typhoon Prediction Model - Hongli Ge; Zhenlu Wang; Bingchen Liang; Zhaozi Zhang; Zhiduo Yan; Ziwang Li (Journal of Marine Science and Engineering, 2021)
This paper sheds light on the effect of combination modes on the evaluation of berthing capacity for Sanya Yazhou Fishing Port (SYFP) under hypothetical typhoon conditions. By statistically analysing the maximum probability of moving speeds and directions of historical typhoons passing through the fishing port, the representative typhoon path was determined with the nonparametric regression method. The designed typhoon wind fields of levels 12–17 were generated based on Holland’s parametric wind model. Then, the MIKE 21 BW model was used to obtain the high-precision wave distribution in the fishing port. The boundary conditions (significant wave height and peak period) of the MIKE 21 BW model were calculated by combining the MIKE 21 SW model with the designed typhoon wind fields. In SYFP, ships usually adopt the modes of multi-ship side-by-side and single anchor mooring during typhoons. In fair weather, approximately 158 vessels can be berthed if they are all large ones, while approximately 735 vessels can be moored if they are all small ones. However, with an increase in typhoon levels, the anchoring area for small vessels decreases. From the perspective of wave distribution in the fishing port, the number of large vessels moored was hardly affected by typhoons. This can be attributed to the breakwater, which significantly decreases the large wave height in the fishing port. Finally, a study on the framework of a method for hazard assessment of berthing capacity in the coming typhoon-driven storm waves was set up.

Enhanced nitrogen and phosphorus removal by natural pyrite–based constructed wetland with intermittent aeration - Liya Li; Jingwei Feng; Liu Zhang; Hao Yin; Chunli Fan; Zechun Wang; Menglei Zhao; Chengchang Ge; Hao Song (Environmental Science and Pollution Research, 2021)

Adsorption Removal of Phosphate and Fluoride from Aqueous Solution Using Oily Sludge-based Pyrolysis Residue - Huifen Yang; Peng Fu; Ge Zhang; Qingping Zhang; Xuan Li (Environmental Processes, 2021)

Closing the loop of DBS using the beta oscillations in cortex - Chen Liu; Ge Zhao; Zihan Meng; Changsong Zhou; Xiaodong Zhu; Wei Zhang; Jiang Wang; Huiyan Li; Hao Wu; Chris Fietkiewicz; Kenneth A. Loparo (Cognitive Neurodynamics, 2021)

An uncharacterized protein from the metagenome with no obvious homology to known lipases shows excellent alkaline lipase properties and potential applications in the detergent industry - Yue Xiao; Yi-De Liu; Ge Yuan; Run-Qian Mao; Gang Li (Biotechnology Letters, 2021)

G1-like PB2 gene improves virus replication and competitive advantage of H9N2 virus - Xiuli Li; Shumiao Qiao; Ying Zhao; Min Gu; Ruyi Gao; Kaituo Liu; Zhichuang Ge; Jing Ma; Xiaoquan Wang; Jiao Hu; Shunlin Hu; Xiaowen Liu; et al. (Virus Genes, 2021)

Evaluation of four artificial diets on demography parameters of Neoseiulus barkeri - Ya-Ying Li; Jin-Ge Yuan; Ming-Xiu Liu; Zi-Hui Zhang; Hai-Wei Zhou; Huai Liu (BioControl, 2021)

Tibetan Plateau v ortex‐associated precipitation and its link with the Tibetan Plateau heating anomaly - Zhiqiang Lin; Weidong Guo; Xiuping Yao; Jun Du; Wenkai Li; Jun Ge (International Journal of Climatology, 2021)
The Tibetan Plateau (TP) is known as the Asian water tower that supplies fresh water for millions of people in Asia. The Tibetan Plateau vortices (TPVs) are one of the major precipitation‐producing weather systems over the TP. The characteristics of TPV‐associated precipitation from 1979 to 2017 are quantitatively analysed based on three daily precipitation datasets. The influence of TPVs on precipitation is more significant in the warm season (May–September) because the precipitation and TPV activities both peak in the warm season. The TPV‐associated precipitation (VAP) dominates the total precipitation over most of the TP in the warm season. The VAP contributes more than 50% of the total precipitation in the warm season over 30% of the area over the TP, particularly in the central TP, while the VAP accounts for more than 25% of the total precipitation in the cold season over about 20% of the area over the TP. Therefore, TPVs are the major systems to produce precipitation on the TP in the warm season, and they are also important in the cold season in certain regions. The interannual variation of VAP is mainly determined by the number, rather than the precipitation intensity, of TPVs. Furthermore, the heating anomaly caused by the TP thermodynamic effect is an influential factor of VAP. Stronger (weaker) TP heating and resulting ascending motion strengthen (attenuate) the convergence near the TP surface and the divergence in the upper troposphere. The thermal adaption‐associated circulation generates more (less) TPVs and VAP.

Controls of Wind-Driven Jet on the Distribution of Pelagic Cnidarians in the Midwestern South China Sea - Ruping Ge; Hongju Chen; Ling Li; Guangxing Liu; Bangqin Huang; Lisha Wang; Yunyun Zhuang; Xin Liu (Frontiers in Marine Science, 2021)
The coastal water transported by the combined action of southwest wind jet and anticyclonic eddy substantially influences the biological processes in the midwestern South China Sea. However, how the wind-driven jet affects the zooplankton community remains unclear. In this study, the species number, abundance, and vertical distribution of medusae were investigated in the wind-driven jet (WJR) and non-wind-driven jet regions (NWJR). The low-salinity and nutrient-rich coastal water substantially influenced species composition, abundance, and vertical distribution of medusae in the WJR. The species number of the meroplanktonic hydromedusae in the WJR was approximately twice that in the NWJR due to the horizontal transport of wind-driven jets. The abundances of holoplanktonic hydromedusae in WJR were 38.2 ± 9.3 ind⋅m –3 , which were thrice of that in the NWJR regions, caused by the abundant diet in the WJR. Additionally, only the abundance of medusae above the thermocline was affected by the coastal water in WJR, while these showed no significant difference below the thermocline between the WJR and the NWJR. Generalized additive model analyses suggested that the diet was the most important factor affecting the abundance of the holoplanktonic hydromedusae and siphonophore, whereas meroplanktonic hydromedusae were influenced by the combination of temperature, salinity, and diet.

Summer Maize Mapping by Compositing Time Series Sentinel-1A Imagery Based on Crop Growth Cycles - Haifeng Tian; Yaochen Qin; Zheng Niu; Li Wang; Shishuai Ge (Journal of the Indian Society of Remote Sensing, 2021)

Simulation and Prediction of the Spatial Dynamics of Land Use Changes Modelling Through CLUE-S in the Southeastern Region of Bangladesh - Shahidul Islam; Yuechen Li; Mingguo Ma; Anxu Chen; Zhongxi Ge (Journal of the Indian Society of Remote Sensing, 2021)

Mechanical energy evolution in the propagation of rock avalanches using field survey and numerical simulation - Yunfeng Ge; Huiming Tang; Changdong Li (Landslides, 2021)

Impacts of ecological restoration on public perceptions of cultural ecosystem services - Qingyue Tan; Chen Gong; Shujie Li; Ning Ma; Fengchi Ge; Mingxiang Xu (Environmental Science and Pollution Research, 2021)

Characteristics of migration and speciation of trace elements during co-processing of antibiotic residues in a circulating fluidized bed - Haiping Xiao; Jinlin Ge; Xinyao Li; Dahai Yan; Zhong Liu (Environmental Science and Pollution Research, 2021)

Seasonal variation of oxidative potential of water-soluble components in PM2.5 and PM1 in the Yangtze River Delta, China - Zhirao Li; Dongyang Nie; Mindong Chen; Pengxiang Ge; Zhengjiang Liu; Xiaoyun Ma; Xinlei Ge; Rui Gu (Air Quality, Atmosphere & Health, 2021)

Isolation of a novel adomavirus from cultured American eels, Anguilla rostrata , with haemorrhagic gill necrosis disease - Jin‐Xian Yang; Xi Chen; Ying‐Ying Li; Tie‐Ying Song; Jun‐Qing Ge (Journal of Fish Diseases, 2021)
Recently, the culture of American eels (Anguilla rostrate) in China has been impacted by emergence of a disease with signs of haemorrhagic gill necrosis. The gills of diseased eels are covered with petecchia and they bleed when the operculum is pressed. In this study, a novel American eel adomavirus (AEAdoV) was isolated from the diseased eels using the eel ovary cell line (EO). The virus proliferated in the EO cells with a maximum TCID 50 /ml of 10 6.29 ± 0.23 at 6 days post‐infection. The virions were non‐enveloped with a diameter of 75–85 nm and shown to be a DNA virus upon 5‐iodo‐2’‐deoxyuridine (IDU) treatment. PCR assays showed that AEAdoV encodes a superfamily 3 helicases (S3H) replicase and shared high similarities with Anguilla marmorata adomavirus (MEAdoV). Although no clinical signs or mortality was observed among the eels injected with AEAdoV, the virus was reisolated from livers, kidneys and gills of injected eels at 35 days post‐injection. Our results suggested that AEAdoV exhibited a latent infection in A. rostrata . The pathogenicity of the AEAdoV needs to be confirmed further.

Comparative Transcriptomic and Proteomic Analysis of Exopalaemon carinicauda in Response to Alkalinity Stress - Zhen Qin; Qianqian Ge; Jiajia Wang; Mingdong Li; Ping Liu; Jian Li; Jitao Li (Frontiers in Marine Science, 2021)
Saline-alkaline waters are stressful environments where most aquatic animals can’t survive normally, and alkalinity is one of the key limited environmental factors. Due to strong adaptability to environment, the ridgetail white prawn Exopalaemon carinicauda is a potential good species suitable for large-scale culture in saline-alkaline waters. Exploring its alkaline adaptability mechanism will help to guide more marine crustaceans to saline-alkaline culture. In this study, an integrative analysis of the gill-specific transcriptome and proteome at 0, 12, and 36 h after alkalinity stress was performed to identify important regulators and pathways involved in alkalinity adaption of E. carinicauda . A total of 3,157 differentially expressed genes (DEGs) and 443 differentially expressed proteins (DEPs) were identified at 12 and 36 h compared with 0 h. Base on the transcriptome analysis, the Gene Ontology (GO) enriched terms were mainly related to ion transport, including “calcium-transporting ATPase activity,” “ATPase coupled ion transmembrane transporter activity,” “divalent inorganic cation transmembrane transporter activity,” etc., and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways mainly refer to the processes of endocrine system at both 12, and 36 h. Based on the proteomic analysis, KEGG pathways related to lipolysis and amino acids metabolism were significantly enriched at 12 h, and carbohydrate metabolism and immune response were significantly enriched at 36 h. There were significantly up-regulated expressions of ion transport related genes including aquaporin, carbonic anhydrase, ammonium transporter Rh type A-like, Na + /H + -exchanger, etc., as well as ion transport proteins including V-type proton ATPase 116 kDa subunit a-like isoform X1, sodium-potassium ATPase beta, vesicle associated membrane protein, etc. after alkalinity exposure, which indicating their important roles in response to alkalinity stress. The results of integrated analysis between proteome and transcriptome showed that up-regulated DEG/DEP (aldehyde dehydrogenase) was significantly enriched at 12 h and the up-regulated DEG/DEP (peptidylglycine alpha) was significantly enriched at 36 h, suggesting the two molecules may be critical in response to alkalinity change. This study reveals the first time-course, gill-specific, combined transcriptomic and proteomic profiling associated with alkalinity adaption of E. carinicauda and provides new insights into the mechanisms underlying the molecular response to alkalinity stress in shrimp.

Functional homoeologous alleles of CONSTANS contribute to seasonal crop type in rapeseed - Qingdong Jin; Shuai Yin; Ge Li; Tao Guo; Ming Wan; Haitao Li; Juanjuan Li; Xianhong Ge; Graham J. King; Zaiyun Li; Jing Wang; Guangsheng Zhou (Theoretical and Applied Genetics, 2021)

Mesenchymal Stem Cell-Based Therapy for Diabetes Mellitus: Enhancement Strategies and Future Perspectives - Haisen Li; Hao Zhu; Ting Ge; Zhifeng Wang; Chao Zhang (Stem Cell Reviews and Reports, 2021)

Fluoride exposure decreased neurite formation on cerebral cortical neurons of SD rats in vitro - Hongmei Ning; Chong Li; Zhihong Yin; Dongfang Hu; Yaming Ge; Lingli Chen (Environmental Science and Pollution Research, 2021)

TRIM25 Rescues Against Doxorubicin-Induced Pyroptosis Through Promoting NLRP1 Ubiquitination - Xiaxia Wang; Zhexun Lian; Yiping Ge; Dongqiang Yu; Shan Li; Kai Tan (Cardiovascular Toxicology, 2021)

Simultaneous spatial-temporal decomposition for connectome-scale brain networks by deep sparse recurrent auto-encoder - Qing Li; Qinglin Dong; Fangfei Ge; Ning Qiang; Xia Wu; Tianming Liu (Brain Imaging and Behavior, 2021)

The impacts of different anticoagulants and long-term frozen storage on multiple metal concentrations in peripheral blood: a comparative study - Yu Bao; Xiaoting Ge; Longman Li; Junxiu He; Sifang Huang; Xiaoyu Luo; Xing Chen; Pan Chen; Xiaobo Yang (BioMetals, 2021)

Sources, Toxicity and Detection Techniques of Semicarbazide: A Review - Xiuhui Tian; Huanjun Li; Dianfeng Han; Fenggong Wen; Huan Liu; Ge Liu; Kaixiu Peng; Xianghong Gong; Xin Liu; Weiyun Wang; Haixia Yu; Yingjiang Xu (Journal of Ocean University of China, 2021)

MiR-137 inhibits the proliferation, invasion and migration of glioma via targeting to regulate EZH2 - Jingshun Gu; Juntong Wang; Aiwu You; Jun Li; Yuyan Zhang; Guomin Rao; Xuehua Ge; Kun Zhang; Xuan Liu; Dongchun Wang (Genes & Genomics, 2021)

Retraction Note to: CiRS-126 inhibits proliferation of ovarian granulosa cells through targeting the miR-21-PDCD4-ROS axis in a polycystic ovarian syndrome model - Jiafeng Lu; Ying Xue; Yuhang Wang; Yang Ding; Qinyan Zou; Min Pan; Longwei Qiao; Chunhua Zhang; Qinyu Ge; Ting Wang; Hong Li (Cell and Tissue Research, 2021)

Genomic molecular signatures determined characterization of Mycolicibacterium gossypii sp. nov., a fast-growing mycobacterial species isolated from cotton field soil - Rui-Rui Huang; Shen-Rong Yang; Cheng Zhen; Xian-Feng Ge; Xin-Kai Chen; Zhi-Qiang Wen; Ya-Nan Li; Wen-Zheng Liu (Antonie van Leeuwenhoek, 2021)

Characterization of a novel shrimp pathogen, Vibrio brasiliensis , isolated from Pacific white shrimp, Penaeus vannamei - Ge Li; Guosi Xie; Hailiang Wang; Xiaoyuan Wan; Xinshu Li; Chengyin Shi; Ziyan Wang; Miao Gong; Ting Li; Ping Wang; Qingli Zhang; Jie Huang (Journal of Fish Diseases, 2021)
A novel pathogenic strain Vibrio 20190611023 was isolated from the hepatopancreas of moribund cultured Penaeus vannamei suffering from black gill disease. This strain was identified as V . brasiliensis based on the phylogenetic analyses of 16S rDNA gene and five other housekeeping genes (i.e., gapA , ftsZ , mreB , topA and gyrB ). Some biochemical features of this strain were determined with an API 20NE system, and its haemolytic activity was determined using a sheep blood agar plate. The pathogenicity of this isolate 20190611023 was confirmed by the experimental challenge tests and histopathological examinations. P. vannamei were challenged via reverse gavage with different doses of bacterial suspensions. The calculated median lethal dose (LD 50 ) was (3.16 ± 1.78) × 10 5 CFU/g (body weight). Moreover, antibiotic susceptibility tests were performed, the results of which showed that the strain 20190611023 was sensitive to chloramphenicol, compound sulphamethoxazole, ciprofloxacin, doxycycline and oxacillin, but resistant to erythromycin, kanamycin, gentamicin, cefoperazone, ceftriaxone, cefamezin and piperacillin. To our knowledge, this is the first report for demonstrating V . brasiliensis as a shrimp pathogen, which expands the host range of V . brasiliensis infection. The present study highlights that more attention should be paid to this novel pathogen in intensive shrimp aquaculture.

Full-Length Transcriptome Sequencing From the Longest-Lived Freshwater Bony Fish of the World: Bigmouth Buffalo (Ictiobus Cyprinellus) - Hailong Ge; Haoyu Zhang; Lijun Yang; Haoyu Wang; Limei Tu; Zhuojin Jiang; Jing Zheng; Bolin Chen; Juan Chen; Yun Li; Zhijian Wang (Frontiers in Marine Science, 2021)

A semi-supervised learning method for hyperspectral imagery based on self-training and local-based affinity propagation - Haimiao Ge; Haizhu Pan; Liguo Wang; Cheng Li; Yanzhong Liu; Wenlong Zhu; Yanping Teng (International Journal of Remote Sensing, 2021)

Development of nuclear and chloroplast polymorphic microsatellites for Crossostephium chinense (Asteraceae) - Luxian Liu; Shook Ling Low; Shota Sakaguchi; Yu Feng; Binjie Ge; Kamil Konowalik; Pan Li (Molecular Biology Reports, 2021)

Biotreatment of Cr(VI) and pyrene combined water pollution by loofa-immobilized bacteria - Xinjiao Dong; Yaru Li; Rui Zhu; Chuanhua Wang; Shimei Ge (Environmental Science and Pollution Research, 2021)

Ras subfamily GTPases regulate development, aflatoxin biosynthesis and pathogenicity in the fungus Aspergillus flavus - Zhuo Zhu; Gengli Ma; Mingkun Yang; Can Tan; Guang Yang; Sen Wang; Na Li; Feng Ge; Shihua Wang (Environmental Microbiology, 2021)
Summary Ras subfamily proteins are molecular switches in signal transduction pathways of many eukaryotes that regulate a variety of cellular processes. Here, the Ras subfamily, encoded by six genes, was identified in Aspergillus flavus : rasA , rasB , rasC , rab‐33 , rheb and rsr1 . The rsr1 deletion mutant (∆ rsr1 ), rheb deletion mutant (∆ rheb ) and double deletion mutant (∆ rheb/rsr1 ) displayed significantly decreased growth and sporulation. Sclerotia formation was significantly decreased for ∆ rheb or ∆ rheb/rsr1 but increased for ∆ rsr1 . Aflatoxin production was significantly increased in ∆ rheb but decreased in ∆ rsr1 and ∆ rheb/rsr1 . We found that rsr1 and rheb are crucial for the pathogenicity of A . flavus . Quantitative proteomics identified 520 differentially expressed proteins (DEPs) for the ∆ rsr1 mutant and 133 DEPs for the ∆ rheb mutant. These DEPs were annotated in multiple biological processes and KEGG pathways in A . flavus . Importantly, we identified the cytokinesis protein SepA in the protein–protein interaction network of rsr1 , and deletion mutants showed that SepA has pleiotropic effects on growth and AF biosynthesis, which may depend on Rsr1 for regulation in A . flavus . Our results indicated that these Ras subfamily proteins exhibited functional redundancy with each other but there were also differences in A . flavus .

Can Upregulation of Pluripotency Genes Enhance Stemness of Mesenchymal Stem Cells? - Kejia Li; Yangzi Jiang; Zheng Yang; Boon Chin Heng; Hua Tian; Zigang Ge (Stem Cell Reviews and Reports, 2021)

Effects of different types of land-use on taxonomic and functional diversity of benthic macroinvertebrates in a subtropical river network - Zhenyuan Liu; Zhengfei Li; Diego M. P. Castro; Xiang Tan; Xiaoming Jiang; Xingliang Meng; Yihao Ge; Zhicai Xie (Environmental Science and Pollution Research, 2021)

Refractory organic compounds in coal chemical wastewater treatment by catalytic ozonation using Mn-Cu-Ce/Al2O3 - Kang-He Zhao; Yu-Long Ma; Feng Lin; Shao-Ying Ge; Li Zhu (Environmental Science and Pollution Research, 2021)

Exogenous Glutathione Alleviates Cadmium Toxicity in Wheat by Influencing the Absorption and Translocation of Cadmium - Ge-Zi Li; Shi-Juan Chen; Na-Ying Li; Ying-Ying Wang; Guo-Zhang Kang (Bulletin of Environmental Contamination and Toxicology, 2021)
Cadmium (Cd), a toxic heavy metal, is harmful to plants and human health. Glutathione (GSH) could alleviate Cd toxicity of plant species, whereas its mechanism responsible for wheat remains poorly understood. Here, we found that exogenous GSH application significantly increased the fresh and dry weight, root elongation, chlorophyll contents, while decreased the contents of malondialdehyde (MDA) and GSH, and translocation factor of Cd compared with Cd treatment. Moreover, GSH application significantly increased activities of antioxidant enzymes and expression of related genes, which involved in GSH synthesis, especially in roots. In addition, we found that GSH application suppressed Cd-induced expression of metal transporter genes TaNramp1 , TaNramp5 , TaHMA2 , TaHMA3 , TaLCT1 and TaIRT2 in roots. Taken together, our results suggested that GSH could alleviate Cd toxicity in wheat by increasing GSH synthesis gene expression or suppressing Cd transporter genes expression, and further affecting Cd uptake and translocation in wheat plants.

Diversity and co-occurrence network modularization of bacterial communities determine soil fertility and crop yields in arid fertigation agroecosystems - Zhencheng Ye; Jing Li; Jie Wang; Chao Zhang; Guobin Liu; Qin’ge Dong (Biology and Fertility of Soils, 2021)

Genetic changes and evolutionary analysis of canine circovirus - Lin Wang; Yifan li; Zhiyuan Guo; Ying Yi; Han Zhang; Haikun Shangguan; Chengshi Huang; Junwei Ge (Archives of Virology, 2021)

Sporadic hand, foot, and mouth disease cases associated with non-C4 enterovirus 71 strains in Xiamen, China, from 2009 to 2018 - Mengyuan Chen; Shuizhen He; Qiang Yan; Jianmei Zhang; Caiyu Li; Xiaosong Su; Shiyin Zhang; Tingdong Li; Shengxiang Ge; Min Chen; Jun Zhang; Ningshao Xia (Archives of Virology, 2021)

Molecular cloning and sequence characterization of common carp (Cyprinus carpio) integrin β1 (ITGβ1) and its temporal expression in response to CyHV-3 - Xiaona Jiang; Jiaxin Sun; Chitao Li; Xuesong Hu; Yanlong Ge; Bao Li; Lianyu Shi; Zhiying Jia (Aquaculture International, 2021)

Transcriptome analysis reveals hub genes in the hepatopancreas of Exopalaemon carinicauda in response to hypoxia and reoxygenation - Wenjun Shi; Pan Wang; Runhao Hu; Xihe Wan; Hui Shen; Hui Li; Libao Wang; Yi Qiao; Ge Jiang; Jie Cheng; Zeyu Yang (Aquaculture International, 2021)

Calibrating receiver-type-dependent wide-lane uncalibrated phase delay biases for PPP integer ambiguity resolution - Bobin Cui; Pan Li; Jungang Wang; Maorong Ge; Harald Schuh (Journal of Geodesy, 2021)
Wide-lane (WL) uncalibrated phase delay (UPD) is usually derived from Melbourne–Wübbena (MW) linear combination and is a prerequisite in Global Navigation Satellite Systems (GNSS) precise point positioning (PPP) ambiguity resolution (AR). MW is a linear combination of pseudorange and phase, and the accuracy is limited by the larger pseudorange noise which is about one hundred times of the carrier phase noise. However, there exist inconsistent pseudorange biases which may have detrimental effect on the WL UPD estimation, and further degrade user-side ambiguity fixing. Currently, only the large part of pseudorange biases, e.g., the differential code bias (DCB), are available and corrected in PPP-AR, while the receiver-type-dependent biases have not yet been considered. Ignoring such kind of bias, which could be up to 20 cm, will cause the ambiguity fixing failure, or even worse, the incorrect ambiguity fixing. In this study, we demonstrate the receiver-type-dependent WL UPD biases and investigate their temporal and spatial stability, and further propose the method to precisely estimate these biases and apply the corrections to improve the user-side PPP-AR. Using a large data set of 1560 GNSS stations during a 30-day period, we demonstrate that the WL UPD deviations among different types of receivers can reach ± 0.3 cycles. It is also shown that such kind of deviations can be calibrated with a precision of about 0.03 cycles for all Global Positioning System (GPS) satellites. On the user side, ignoring the receiver-dependent UPD deviation can cause significant positioning error up to 10 cm. By correcting the deviations, the positioning performance can be improved by up to 50%, and the fixing rate can also be improved by 10%. This study demonstrates that for the precise and reliable PPP-AR, the receiver-dependent UPD deviations cannot be ignored and have to be handled.

Effects of Dual Fronts on the Spatial Pattern of Chlorophyll-a Concentrations in and off the Changjiang River Estuary - Weiqi Li; Jianzhong Ge; Pingxing Ding; Jianfei Ma; Patricia M. Glibert; Dongyan Liu (Estuaries and Coasts, 2021)

Forging or casting: new evidence of iron production in the Chengdu Plain in the Han dynasty - Mengyi Zhang; Linjie Ge; Tian Qiu; Qianqian Gan; Bo Yang; Yuniu Li (Archaeological and Anthropological Sciences, 2021)

Anthropogenic Effects on Biogenic Secondary Organic Aerosol Formation - Li Xu; Lin Du; Narcisse T. Tsona; Maofa Ge (Advances in Atmospheric Sciences, 2021)