Transformation of vivianite in intertidal sediments with contrasting sulfide conditions - L. Joëlle Kubeneck; Luiza Notini; Katherine A. Rothwell; Giulia Fantappiè; Thomas Huthwelker; Laurel K. ThomasArrigo; Ruben Kretzschmar (Geochimica et Cosmochimica Acta, 2024)

High contributions of fossil fuel sources to char-EC/soot-EC at a high-altitude site: Direct radiative effects and transport pathway - Huikun Liu; Qiyuan Wang; Yao Qu; Jie Tian; Li Li; Nan Ma; Yaqing Zhou; WeiKang Ran; Hui Su; Yongming Han; Giulia Pavese; Junji Cao (Fuel, 2024)

Exploring the effect of naturalness on consumer wine choices: Evidence from a survey in Italy - Claudia Bazzani; Giulia Maesano; Diego Begalli; Roberta Capitello (Food Quality and Preference, 2024)

Cell wall polysaccharides, phenolic extractability and mechanical properties of Aleatico winegrapes dehydrated under sun or in controlled conditions - Giulia Scalzini; Aude Vernhet; Stéphanie Carillo; Stéphanie Roi; Frédéric Véran; Bodil Jørgensen; Jeanett Hansen; Simone Giacosa; Susana Río Segade; Maria Alessandra Paissoni; Thierry Doco; Luca Rolle; et al. (Food Hydrocolloids, 2024)

Antimicrobial Blue Light (aBL) as a potential tool to reduce bacterial spoilage in the fishery chain - Viviana T. Orlandi; Fabrizio Bolognese; Nicola Trivellin; Giulia Cipriano; Pasquale Ricci; Roberto Carlucci (Food Control, 2024)

Different greenness exposure in Europe and respiratory outcomes in youths. A systematic review and meta-analysis - Giulia Squillacioti; Salvatore Fasola; Federica Ghelli; Nicoletta Colombi; Alessandra Pandolfo; Stefania La Grutta; Giovanni Viegi; Roberto Bono (Environmental Research, 2024)

Tannery sludge valorization through zeolite-assisted anaerobic process for short-chain fatty acids (SCFAs) production - Giulia Adele Tuci; Francesco Valentino; Paolo Pavan; Marco Gottardo (Environmental Research, 2024)

Damage detection of prestressed concrete beams affected by shear and flexure cracks through vibration monitoring - Emanuele Gandelli; Giulia Rossini; Stefano Giuseppe Mantelli; Fausto Minelli (Engineering Structures, 2024)

Unequal access to cultural ecosystem services of green spaces within the city of Rome – A spatial social media-based analysis - Giulia Benati; Fulvia Calcagni; Federico Martellozzo; Andrea Ghermandi; Johannes Langemeyer (Ecosystem Services, 2024)

Trophic niche overlap of deep-sea fish species revealed by the combined approach of stomach contents and stable isotopes analysis in the Central Tyrrhenian Sea - Davide Cicala; Alice Sbrana; Tommaso Valente; Daniela Berto; Federico Rampazzo; Maria Flavia Gravina; Giulia Maiello; Tommaso Russo (Deep Sea Research Part I: Oceanographic Research Papers, 2024)

Exploring the geomorphological adequacy of the landslide susceptibility maps: A test for different types of landslides in the Bidente river basin (northern Italy) - Chiara Martinello; Michele Delchiaro; Giulia Iacobucci; Chiara Cappadonia; Edoardo Rotigliano; Daniela Piacentini (CATENA, 2024)

Helios and Juliette: Two falsely acclaimed medicanes? - Leo Pio D'Adderio; Giulia Panegrossi; Stavros Dafis; Jean-Francois Rysman; Daniele Casella; Paolo Sanò; Alessandro Fuccello; Mario Marcello Miglietta (Atmospheric Research, 2024)

Procalcitonin and carbonylated protein concentrations in equine synovial fluid - Irene Nocera; Micaela Sgorbini; Valentina Meucci; Luis A. Gracia-Calvo; Heidi Tapio; Marcello Camisi; Giulia Sala; Simonetta Citi (Veterinary Research Communications, 2024)

Evaluation of a smartphone electrocardiograph in healthy foals and comparison to standard base-apex electrocardiography - Francesca Bindi; Tommaso Vezzosi; Giulia Sala; Francesca Freccero; Paola Marmorini; Francesca Bonelli; Micaela Sgorbini (Veterinary Research Communications, 2024)
Smartphone-based technology for ECG recording has recently spread as a complementary tool for electrocardiographic screening and monitoring in adult horses and in other animal species. The present study aimed to assess the feasibility and accuracy of a smartphone-based ECG in healthy foals. This was a prospective observational study (authorization n. 45,865/2016) including 22 foals aged less than 21 days. A reference standard base-apex ECG (rECG) was acquired, and a smartphone ECG (sECG) was recorded immediately after by using a smartphone-based single lead electrocardiograph. All ECG tracings were evaluated in a blind fashion by a single board-certified cardiologist, who judged whether the tracings were acceptable for interpretation and performed ECG measurements and diagnosis. The Spearman correlation coefficient, the Cohen’s k test and the Bland-Altman test were used to assess the agreement between sECG and rECG. All sECG tracings were acceptable for interpretation. All foals showed sinus rhythm on both rRCG and sECG tracings, with perfect agreement in heart rate classification (κ = 0.87; p < 0.001). No clinically relevant differences were found in the assessment of waves and intervals duration. Concerning P wave and QRS complex polarity, the percentage of agreement between rECG and sECG was 78% and 83%, respectively. About ECG tracing quality, rECG and sECG showed a substantial agreement (κ = 0.624; p < 0.001). In conclusion, the smartphone-based ECG device tested in the present study recorded good quality single-lead ECG tracings in foals, reliable for heart rate and ECG measurements, but different polarity of P waves and QRS complexes was found in some foals in comparison to rECG.

Systemic and local effect of oxidative stress on recurrent aphthous stomatitis: systematic review - Cristina Estornut; Giulia Rinaldi; María Carmen Carceller; Sergio Estornut; Martín Pérez-Leal (Journal of Molecular Medicine, 2024)

Risk of bladder, kidney and prostate cancer from occupational exposure to welding fumes: a systematic review and meta-analysis - Giulia Collatuzzo; Maha Hamdani; Paolo Boffetta (International Archives of Occupational and Environmental Health, 2024)

CCL18, CHI3L1, ANG2, IL-6 systemic levels are associated with the extent of lung damage and radiomic features in SARS-CoV-2 infection - Ilaria Ferrigno; Laura Verzellesi; Marta Ottone; Martina Bonacini; Alessandro Rossi; Giulia Besutti; Efrem Bonelli; Rossana Colla; Nicola Facciolongo; Elisabetta Teopompi; Marco Massari; Pamela Mancuso; et al. (Inflammation Research, 2024)

XFVM modelling of fracture aperture induced by shear and tensile opening - Giulia Conti; Stephan Matthäi; Patrick Jenny (Computational Geosciences, 2024)
In reservoir simulation, it is important to understand the mechanical behaviour of fractured rocks and the effect of shear and tensile displacements of fractures on their aperture. Tensile opening directly enhances the fracture aperture, whereas shear of a preexisting rough-walled fracture creates aperture changes dependent on the local stress state. Since fracture dilatation increases reservoir permeability, both processes must be included in a realistic and consistent manner into the mechanical reservoir simulation model. Here, we use the extended finite volume method (XFVM) to conduct flow and geomechanics simulations. In XFVM, fractures are embedded in a poroelastic matrix and are modelled with discontinuous basis functions. On each fracture segment the tractions and compressive forces are calculated, and one extra degree of freedom is added for both the shear and tensile displacement. In this particular XFVM implementation we assume that linear elasticity and steady state fluid pressure adequately constrain the effective stress. In this paper, shear dilation is not calculated a posteriori, but it enters the equations such that aperture changes directly affect the stress state. This is accomplished by adding shear dilation to the displacement gradients and therefore ascertains a consistent representation in the stress-strain relations and force balances. We illustrate and discuss the influence of this extra term in two simple test cases and in a realistic layer-restricted two-dimensional fracture network subjected to plausible in situ stress and pore pressure conditions.

External validation of a red cell-based blood prognostic score in patients with metastatic renal cell carcinoma treated with first-line immunotherapy combinations - Michele Maffezzoli; Matteo Santoni; Giulia Mazzaschi; Sara Rodella; Eleonora Lai; Marco Maruzzo; Umberto Basso; Davide Bimbatti; Roberto Iacovelli; Annunziato Anghelone; Ondřej Fiala; Sara Elena Rebuzzi; et al. (Clinical & Experimental Metastasis, 2024)
Immunotherapy combinations with tyrosine-kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs) had significantly improved outcomes of patients with mRCC. Predictive and prognostic factors are crucial to improve patients’ counseling and management. The present study aimed to externally validate the prognostic value of a previously developed red cell-based score , including hemoglobin (Hb), mean corpuscular volume (MCV) and red cell distribution width (RDW), in patients with mRCC treated with first-line immunotherapy combinations (TKI plus ICI or ICI plus ICI). We performed a sub-analysis of a multicentre retrospective observational study (ARON-1 project) involving patients with mRCC treated with first-line immunotherapy combinations. Uni- and multivariable Cox regression models were used to assess the correlation between the red cell-based score and progression-free survival (PFS), and overall survival (OS). Logistic regression were used to estimate the correlation between the score and the objective response rate (ORR). The prognostic impact of the red cell-based score on PFS and OS was confirmed in the whole population regardless of the immunotherapy combination used [median PFS (mPFS): 17.4 vs 8.2 months, HR 0.66, 95% CI 0.47–0.94; median OS (mOS): 42.0 vs 17.3 months, HR 0.60, 95% CI 0.39–0.92; p < 0.001 for both]. We validated the prognostic significance of the red cell-based score in patients with mRCC treated with first-line immunotherapy combinations. The score is easy to use in daily clinical practice and it might improve patient counselling.

Pathways from research to sustainable development: Insights from ten research projects in sustainability and resilience - Anna Scaini; Joseph Mulligan; Håkan Berg; Albert Brangarí; Vera Bukachi; Sebastian Carenzo; Da Chau Thi; Colin Courtney-Mustaphi; Anneli Ekblom; Hanne Fjelde; Mathias Fridahl; Anders Hansson; et al. (Ambio, 2024)
Drawing on collective experience from ten collaborative research projects focused on the Global South, we identify three major challenges that impede the translation of research on sustainability and resilience into better-informed choices by individuals and policy-makers that in turn can support transformation to a sustainable future. The three challenges comprise: (i) converting knowledge produced during research projects into successful knowledge application; (ii) scaling up knowledge in time when research projects are short-term and potential impacts are long-term; and (iii) scaling up knowledge across space, from local research sites to larger-scale or even global impact. Some potential pathways for funding agencies to overcome these challenges include providing targeted prolonged funding for dissemination and outreach, and facilitating collaboration and coordination across different sites, research teams, and partner organizations. By systematically documenting these challenges, we hope to pave the way for further innovations in the research cycle.

Acute generalized pustulosis secondary to lamotrigine: from clinical to anatomopathological description - André Eduardo de Almeida Franzoi; Emanuelle Leonel Ferreira; Giulia Murillo Wollmann; Melina Paula de Araujo Meskau; Tallulah Spina Tensini (Acta Neurologica Belgica, 2024)

Stable mean trophic level and decreasing fish size in Central Amazonian fishery landings - Octavio Ferreira de Matos; Diego Valente Pereira; Giulia Cristina dos Santos Lopes; Marcos de Almeida Mereles; Vandick da Silva Batista; Carlos Edwar de Carvalho Freitas; Flávia Kelly Siqueira‐Souza (Fisheries Management and Ecology, 2024)
Evaluating trends in fisheries, especially data‐limited small‐scale fisheries, is challenging. We used fish landings to evaluate changes in composition of fish landings in rivers of the Central Amazon, from a discontinuous historical 28‐year series of landings from different data collection systems in main ports of the city of Manaus, the largest consumer market in the region. Annual mean trophic level (MTL), fishing‐in‐balance index (FiB), and mean landed size (MSL) were estimated. MTL did not decline, FiB was positive in most years, and MSL declined. Relative catches of certain fish species were replaced by others at a similar trophic level, but mean body size declined over time. We conclude that fishing in the Central Amazon is not sustainable and would benefit from better management strategies.

Revealing the genetic traits of the foodborne microbial genus Hafnia : Implications for the human gut microbiome - Federico Fontana; Giulia Longhi; Elisa Carli; Giulia Alessandri; Leonardo Mancabelli; Gabriele Andrea Lugli; Chiara Tarracchini; Alice Viappiani; Rosaria Anzalone; Francesca Turroni; Christian Milani; Marco Ventura (Environmental Microbiology, 2024)
The bacterial genus Hafnia has recently attracted attention due to its complex metabolic features and host‐interaction capabilities, which are associated with health benefits, primarily weight loss. However, significant gaps remain in our understanding of the genomic characteristics of this emerging microbial group. In this study, we utilized all available high‐quality genomes of Hafnia alvei and Hafnia paralvei to uncover the broad distribution of Hafnia in human and honeybee guts, as well as in dairy products, by analysing 1068 metagenomic datasets. We then investigated the genetic traits related to Hafnia 's production of vitamins and short‐chain fatty acids (SCFAs) through a comparative genomics analysis that included all dominant bacterial species in the three environments under study. Our findings underscore the extensive metabolic capabilities of Hafnia, particularly in the production of vitamins such as thiamine (B1), nicotinate (B3), pyridoxine (B6), biotin (B7), folate (B9), cobalamin (B12), and menaquinone (K2). Additionally, Hafnia demonstrated a conserved genetic makeup associated with SCFA production, including acetate, propanoate, and butanoate. These metabolic traits were further confirmed using RNAseq analyses of a newly isolated H. paralvei strain T10. Overall, our study illuminates the ecological distribution and genetic attributes of this bacterial genus, which is of increasing scientific and industrial relevance.

Machine learning methods to predict sea surface temperature and marine heatwave occurrence: a case study of the Mediterranean Sea - Giulia Bonino; Giuliano Galimberti; Simona Masina; Ronan McAdam; Emanuela Clementi (Ocean Science, 2024)
Marine heatwaves (MHWs) have significant social and ecological impacts, necessitating the prediction of these extreme events to prevent and mitigate their negative consequences and provide valuable information to decision-makers about MHW-related risks. In this study, machine learning (ML) techniques are applied to predict sea surface temperature (SST) time series and marine heatwaves in 16 regions of the Mediterranean Sea. ML algorithms, including the random forest (RForest), long short-term memory (LSTM), and convolutional neural network (CNN), are used to create competitive predictive tools for SST. The ML models are designed to forecast SST and MHWs up to 7 d ahead. For each region, we performed 15 different experiments for ML techniques, progressively sliding the training and the testing period window of 4 years from 1981 to 2017. Alongside SST, other relevant atmospheric variables are utilized as potential predictors of MHWs. Datasets from the European Space Agency Climate Change Initiative (ESA CCI SST) v2.1 and the European Centre for Medium-Range Weather Forecasts (ECMWF) ERA5 reanalysis from 1981 to 2021 are used to train and test the ML techniques. For each area, the results show that all the ML methods performed with minimum root mean square errors (RMSEs) of about 0.1 °C at a 1 d lead time and maximum values of about 0.8 °C at a 7 d lead time. In all regions, both the RForest and LSTM consistently outperformed the CNN model across all lead times. LSTM has the highest predictive skill in 11 regions at all lead times. Importantly, the ML techniques show results similar to the dynamical Copernicus Mediterranean Forecasting System (MedFS) for both SST and MHW forecasts, especially in the early forecast days. For MHW forecasting, ML methods compare favorably with MedFS up to 3 d lead time in 14 regions, while MedFS shows superior skill at 5 d lead time in 9 out of 16 regions. All methods predict the occurrence of MHWs with a confidence level greater than 50 % in each region. Additionally, the study highlights the importance of incoming solar radiation as a significant predictor of SST variability along with SST itself.

Both humans and conspecifics provide social support to dog and wolf puppies - Giulia Cimarelli; Friederike Range; Katrin Hann; Kurt Kotrschal; Márta Gácsi; Zsófia Virányi (Animal Behaviour, 2024)

The contamination of in situ archaeological remains: A pilot analysis of microplastics in sediment samples using μFTIR - Jeanette M. Rotchell; Freija Mendrik; Emma Chapman; Paul Flintoft; Ian Panter; Giulia Gallio; Christine McDonnell; Catriona R. Liddle; David Jennings; John Schofield (Science of The Total Environment, 2024)

Towards a standardized, ground-based network of hyperspectral measurements: Combining time series from autonomous field spectrometers with Sentinel-2 - Paul Naethe; Andrea De Sanctis; Andreas Burkart; Petya K.E. Campbell; Roberto Colombo; Biagio Di Mauro; Alexander Damm; Tarek El-Madany; Francesco Fava; John A. Gamon; Karl F. Huemmrich; Mirco Migliavacca; et al. (Remote Sensing of Environment, 2024)

Characterization of fungal species involved in white haze disorder on apples in Northern Italy and description of Golubevia mali sp. nov. and Entyloma mali sp. nov. - Vladimiro Guarnaccia; Giulia M.E. Remolif; Luca Nari; Valeria Gualandri; Dario Angeli; Sabine Oettl; Jan Dijksterhuis; Teun Boekhout; Davide Spadaro (Postharvest Biology and Technology, 2024)

Corrigendum to “In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice” [NeuroToxicology, 83 (2021), 1–13] - Giulia Costa; Stefan Spulber; Elena Paci; Maria Antonietta Casu; Sandra Ceccatelli; Nicola Simola; Micaela Morelli (NeuroToxicology, 2024)

Data-driven statistical optimization of a groundwater monitoring network - Mara Meggiorin; Nuria Naranjo-Fernández; Giulia Passadore; Andrea Sottani; Gianluca Botter; Andrea Rinaldo (Journal of Hydrology, 2024)

Life cycle assessment of lattice structures: Balancing mass saving and productivity - Giulia Colombini; Roberto Rosa; Anna Maria Ferrari; Silvio Defanti; Elena Bassoli (Journal of Cleaner Production, 2024)

Stable isotope ratios and current-use pesticide levels in edible insects: Implications on chemical food safety - Alicia Macan Schönleben; Shanshan Yin; Ethan Strak; Alison Johnson; Lidia Belova; Yu Ait Bamai; Alexander L.N. van Nuijs; Giulia Poma; Adrian Covaci (Food Research International, 2024)

Exploring the hidden chemical landscape: Non-target and suspect screening analysis for investigating solid waste-associated environments - Jorgelina Cecilia Altamirano; Shanshan Yin; Lidia Belova; Giulia Poma; Adrian Covaci (Environmental Research, 2024)

Identification, semi-quantification and risk assessment of contaminants of emerging concern in Flemish indoor dust through high-resolution mass spectrometry - Lidia Belova; Maarten Roggeman; Fatima den Ouden; Paulien Cleys; Yu Ait Bamai; Shanshan Yin; Lu Zhao; Jasper Bombeke; Jan Peters; Patrick Berghmans; Celine Gys; Alexander L.N. van Nuijs; et al. (Environmental Pollution, 2024)

Impact of heat-not-burn cigarette passive smoking on children's oxidative stress, endothelial and platelet function - Lorenzo Loffredo; Roberto Carnevale; Arianna Pannunzio; Bianca Laura Cinicola; Ilaria Maria Palumbo; Simona Bartimoccia; Cristina Nocella; Vittoria Cammisotto; Francesco Violi; Giuseppe Biondi-Zoccai; Giacomo Frati; Anna Maria Zicari; et al. (Environmental Pollution, 2024)

Foliar application of natural zeolites affects the growth and productivity of processing tomato - Giulia Conversa; Salvatore Pacifico; Paolo La Rotonda; Corrado Lazzizera; Anna Bonasia; Antonio Elia (European Journal of Agronomy, 2024)

Dynamics and drivers of carbon sequestration and storage capacity in Phragmites australis-dominated wetlands - Giulia Silan; Alessandro Buosi; Camilla Bertolini; Adriano Sfriso (Estuarine, Coastal and Shelf Science, 2024)

An annotated timeline of sensitivity analysis - Stefano Tarantola; Federico Ferretti; Samuele Lo Piano; Mariia Kozlova; Alessio Lachi; Rossana Rosati; Arnald Puy; Pamphile Roy; Giulia Vannucci; Marta Kuc-Czarnecka; Andrea Saltelli (Environmental Modelling & Software, 2024)

Fractionation and characterization of cell wall polysaccharides from coffee (Coffea arabica L.) pulp - Luis Henrique Reichembach; Giulia Karolline Kaminski; Juliana Bello Baron Maurer; Carmen Lúcia de Oliveira Petkowicz (Carbohydrate Polymers, 2024)

Cloudwork als Chance für den Globalen Süden? - Tatiana López; Patrick Feuerstein; Janine de Vera; Giulia Varaschin; Zeynep Karlıdağ; Mark Graham (Standort, 2024)
Zusammenfassung Online-Plattformarbeit – auch als „Cloudwork“ bekannt – hat in den letzten Jahren ein rasantes Wachstum verzeichnet. Entwicklungspolitische Debatten betonen in diesem Zusammenhang die neuen Einkommens- und professionellen Entwicklungschancen für gut ausgebildete, jedoch oft unterbeschäftigte Arbeiter*innen aus Ländern des Globalen Südens. Cloudwork-Plattformen bieten diesen Arbeiter*innen neue Zugänge zu Kund*innen und Aufträgen aus dem Globalen Norden, die in Dollar oder Euro vergütet werden. Gleichzeitig zeigen Studien jedoch, dass Online-Plattformarbeit oftmals mit unsicheren Bedingungen und psychischen Belastungen einhergeht. Dieser Beitrag untersucht die Einkommens- und professionellen Entwicklungschancen von Online-Plattformarbeiter*innen aus dem Globalen Süden im Übersetzungs- und Transkriptionssektor. Er stützt sich auf eine quantitative Online-Befragung mit 401 Plattformarbeiter*innen (darunter 266 aus dem Globalen Süden), die im Jahr 2022 im Rahmen des Fairwork-Projekts durchgeführt wurde. Die Ergebnisse zeigen, dass die Einkommens- und professionellen Entwicklungschancen von Cloud-Arbeiter*innen durch ihre geographische Verortung und die Art der Arbeitsorganisation auf den einzelnen Plattformen beeinflusst werden. Arbeiter*innen aus dem Globalen Süden mussten im Vergleich zu ihren Kolleg*innen aus dem Globalen Norden mehr unbezahlte Arbeitszeit (z. B. in die Suche nach Jobs) investieren. Trotzdem konnten Arbeiter*innen aus dem Globalen Süden auch unter Einberechnung der unbezahlten Arbeitsstunden eher ein Einkommen über dem lokalen Mindestlohnniveau erzielen – eine Tatsache, die sich durch internationale Unterschiede in den lokalen Lohnniveaus erklären lässt. Unbezahlte Arbeitszeit ist besonders ausgeprägt auf sogenannten „Micro-Task-Plattformen“ im Transkriptionssektor, da hier das Überangebot von Arbeitskräften in der Regel sehr hoch ist. Insgesamt verdeutlicht unser Beitrag die Machtposition von Plattformunternehmen, welche neue globale Geographien der Online-Arbeit hervorbringen und kontrollieren, und damit Chancen für gute Arbeit im Globalen Süden beeinflussen.

Warming-induced flowering and fruiting in the seagrass Posidonia oceanica and uncertainties due to context-dependent features - Patrizia Stipcich; Gabriella La Manna; Giulia Ceccherelli (Marine Biology, 2024)
This study explores the impacts of global warming on the reproductive efforts of Posidonia oceanica , a key seagrass species endemic to the Mediterranean Sea. By analyzing data from five areas in Sardinia in February 2023, we have investigated the relationship between thermal descriptors and P. oceanica flowering and fruiting variables. In fact, whether climate change has been affected the distribution of seagrasses by changing their reproductive efforts is still controversial and our findings contribute to this ongoing debate, highlighting a noticeable increase in reproductive events potentially affected by rising temperature. Overall, mean summer sea surface temperature (SST) was positively associated to inflorescence density, presence of living fruits and fruit size; living fruits and fruit size were also influenced positively by the maximum SST within 3 months before sampling (November–February). Both flowering and fruiting were negatively affected by the maximum SST within 1 month before inflorescence observation and mean winter SST, respectively, suggesting that P. oceanica reproductive effort depends on the duration and the temporal context in which the anomaly occurs. However, the high variability between meadows of the same area highlights the need of future studies to focus on the uncertainties related to local factors.

Occupational-related exposure to diesel exhaust and risk of leukemia: systematic review and meta-analysis of cohort studies - Darshi Shah; Vincent DeStefano; Giulia Collatuzzo; Federica Teglia; Paolo Boffetta (International Archives of Occupational and Environmental Health, 2024)

Visual motion hypersensitivity, from spaceflight to Parkinson’s disease—as the chiasmatic cistern may be impacted by microgravity together with normal terrestrial gravity-opposition physiology in the brain - J. Howard Jaster; Joshua Ong; Giulia Ottaviani (Experimental Brain Research, 2024)

Why Circular Business Models Fail And What To Do About It: A Preliminary Framework And Lessons Learned From A Case In The European Union (Eu) - Brian Baldassarre; Giulia Calabretta (Circular Economy and Sustainability, 2024)
The circular economy aims to decouple economic growth from negative environmental impacts. To achieve this goal, circular economy concepts and policies must be implemented in practice by organizations through new circular business models. However, organizations often fail to implement circular business models on the market at scale. This is a major problem in business innovation practice, while a knowledge gap about the underlying implementation challenges remains in the scientific literature. More research on the subject is needed. The objective of this study is contributing to shed light into the gap with empirical insights. Using an action research method within an EU innovation project, this article proposes a preliminary empirical framework that links the value proposition, creation, delivery, and capture dimensions of a circular business models with specific cultural, regulatory, economic, and technical barriers that might hinder implementation. Based on the framework, four lessons to support managerial action are provided. Future research might build upon this work by systematically collecting and structuring more granular empirical data about the specific reasons why new circular business models fail to be implemented by organizations, across different sectors and geographical areas.

Critical Needs for Integrated Surveillance: Wastewater-Based and Clinical Epidemiology in Evolving Scenarios with Lessons Learned from SARS-CoV-2 - Annalaura Carducci; Ileana Federigi; Giulia Lauretani; Sara Muzio; Alessandra Pagani; Nebiyu Tariku Atomsa; Marco Verani (Food and Environmental Virology, 2024)
During the COVID-19 pandemic, wastewater-based epidemiology (WBE) and clinical surveillance have been used as tools for analyzing the circulation of SARS-CoV-2 in the community, but both approaches can be strongly influenced by some sources of variability. From the challenging perspective of integrating environmental and clinical data, we performed a correlation analysis between SARS-CoV-2 concentrations in raw sewage and incident COVID-19 cases in areas served by medium-size wastewater treatment plants (WWTPs) from 2021 to 2023. To this aim, both datasets were adjusted for several sources of variability: WBE data were adjusted for factors including the analytical protocol, sewage flow, and population size, while clinical data adjustments considered the demographic composition of the served population. Then, we addressed the impact on the correlation of differences among sewerage networks and variations in the frequency and type of swab tests due to changes in political and regulatory scenarios. Wastewater and clinical data were significantly correlated when restrictive containment measures and limited movements were in effect ( ρ = 0.50) and when COVID-19 cases were confirmed exclusively through molecular testing ( ρ = 0.49). Moreover, a positive (although weak) correlation arose for WWTPs located in densely populated areas ( ρ = 0.37) and with shorter sewerage lengths ( ρ = 0.28). This study provides methodological approaches for interpreting WBE and clinical surveillance data, which could also be useful for other infections. Data adjustments and evaluation of possible sources of bias need to be carefully considered from the perspective of integrated environmental and clinical surveillance of infections.

Image-based Appraisal of Woody Starch Reserves in Grapevine - Daniel Grigorie Dinu; Vitale Nuzzo; Giulia Gestri; Giuseppe Montanaro; Laura Rustioni (Agricultural Research, 2024)
Maintaining stable yield in a climate change scenario requires the implementation of adaptive strategies for vine and vineyard management. Knowing the level of starch stored in perennial vine organs may help to reduce the risk of environmental constraints. Therefore, the development of decision support tools is important to assist winegrowers. The aim of this work was to test the possibility of estimating the starch content in grapevine woody tissues using digital imaging analysis. A colorimetric index (CI) based on red ( R ), green ( G ), and blue ( B ) mean pixel values was proposed and compared with an existing spectrophotometric index (SI). Shoots of three grapevine cultivars were collected during the 2020 dormant season and forced to produce new rooted cuttings. From these cuttings, a total of 73 internodes were sampled and their woody sections stained with Lugol’s iodine solution and CI and SI determined. In the three varieties, the CI well correlated with the SI (Spearman’s test ranged from − 0.84 to − 0.93, p R 2 = 0.84) predict the SI confirming it is a reliable method for the digital determination of woody reserves in grapevine, supporting management decisions in viticulture.

Mycorrhizal fungi respiration dynamics in relation to gross primary production in a Hungarian dry grassland - Giulia De Luca; Marianna Papp; Szilvia Fóti; Katalin Posta; Ádám Mészáros; Krisztina Pintér; Zoltán Nagy; Evelin Ramóna Péli; Sándor Fekete; János Balogh (Plant and Soil, 2024)
Aims Soil respiration (R s ) is a complex process including a wide range of soil biota and pathways of carbon cycling, all being under the control of various drivers. The most important biotic driver is the photosynthetic activity of the vegetation providing supply mainly for the autotrophic component of R s : roots and their symbiotic partners. The objective of this study was to describe the time-lagged relationship between gross primary production (GPP) and the mycorrhizal R s component in order to determine the amount of carbon derived from GPP appearing as mycorrhizal respiration (R myc ). Methods Measurements of R s were conducted in three treatments - (i) undisturbed, root and arbuscular mycorrhizal fungi (AMF)-included (R s ), (ii) root-excluded (R het+myc ) and (iii) root- and AMF-excluded (R het ) plots - for three consecutive years in a Central-Hungarian dry sandy grassland. GPP data were derived from eddy-covariance measurements, while an automated system was used for continuous measurements of R s . We analysed the relationship between R myc and GPP by using cross-correlation and by fitting sine wave models on the diel datasets. Results GPP was found to be the main driver of R myc , responding with an average time lag of 18 h. The greatest lags were detected during periods characterized by minimal photosynthetic activity, while lags were the smallest during active periods. Conclusion Based on the seasonal changes in the delay, we concluded that GPP and soil temperature had simultaneous effects on the diel pattern of CO 2 emission of the different autotrophic components depending on the vegetation activity and environmental conditions.

Corrigendum: Spatial analysis of demersal food webs through integration of eDNA metabarcoding with fishing activities - Davide Cicala; Giulia Maiello; Fabio Fiorentino; Germana Garofalo; Daniela Massi; Alice Sbrana; Stefano Mariani; Simone D’Alessandro; Matteo Stefani; Lucie Perrodin; Tommaso Russo (Frontiers in Marine Science, 2024)

Signature of the anthropogenic impacts on the epipelagic microbiome of the North-Western Adriatic Sea (Mediterranean Sea) - Giulia Trapella; Daniel Scicchitano; Lucia Foresto; Andrea Nicoló Dell’Acqua; Elena Radaelli; Silvia Turroni; Simone Rampelli; Cinzia Corinaldesi; Giorgia Palladino; Marco Candela (Frontiers in Marine Science, 2024)
Introduction In our paper, we explored the impact of different anthropogenic stressors, namely, mussel farming, methane extraction platforms, and summer mass tourism, on the epipelagic microbiomes of the North-Western Adriatic Sea. Methods By 16S rRNA gene sequencing, we provided the epipelagic microbiome layout from selected sites corresponding to each of the considered impacts. As an unimpacted reference, we used already published 16S rRNA sequencing data. Results According to our findings, each one of the anthropogenic stressors resulted in a peculiar increase of specific epipelagic microbial components, including copiotrophic R-strategists and host-restricted bacteria, as well as some pathobiome components, the latter being detected exclusively in impacted sites. Particularly, potentially harmful pathogenic species such as Legionella impletisoli and Staphylococcus epidermidis have been detected in proximity to the mussel farms, and Escherichia coli and Campylobacter ureolyticus were present close to the methane extraction platform and at the summer mass tourism site, respectively. Particularly, C. ureolyticus is an emerging human gastrointestinal pathogen, capable of destroying intestinal microvilli. Discussion In addition to providing evidence supporting the existence of recognizable and impact-driven fingerprints on the epipelagic marine microbiome peculiar to the different anthropogenic stressors, our findings also raise concern about the ecological relevance of the observed changes, in terms of possible loss of ecosystem services and also for the potential release of pathogenic microorganisms in the environment.

Welfare of rainbow trout at slaughter: Integrating behavioural, physiological, proteomic and quality indicators and testing a novel fast-chill stunning method - João L. Saraiva; Filippo Faccenda; María J. Cabrera-Álvarez; Michele Povinelli; Peter C. Hubbard; Marco Cerqueira; Ana Paula Farinha; Giulia Secci; Maria Vittoria Tignani; Lina F. Pulido Rodriguez; Giuliana Parisi (Aquaculture, 2024)

Genetic variability of Dirofilaria repens isolates from humans and dogs in Italy - Simona Gabrielli; Leonardo Brustenga; Giulia Morganti; Lavinia Ciuca; Giulia Barlozzari; Giulia Rigamonti; Margherita Orlandi; Monica Sforna; Fabrizia Veronesi (Veterinary Parasitology, 2024)

Cushioned and high-speed centrifugation improve sperm recovery rate but affect the quality of fresh and cryopreserved feline spermatozoa - Alessia Gloria; Marco Cunto; Daniele Zambelli; Claudia Bracco; Giulia Ballotta; Alberto Contri (Theriogenology, 2024)

Equivalent fundamental period of bridge piers on caisson foundations from dynamic centrifuge testing - Domenico Gaudio; Gopal S.P. Madabhushi; Sebastiano Rampello; Giulia M.B. Viggiani (Soil Dynamics and Earthquake Engineering, 2024)

Green next-generation excipients enriched in polyphenols from recovery of grape processing waste black bentonite: Influence of unconventional extraction solvents on antioxidant properties and composition. - Giulia Di Prima; Elena Belfiore; Giuseppe Angellotti; Viviana De Caro (Sustainable Chemistry and Pharmacy, 2024)

A full-length SSU rRNA-based workflow for high-resolution monitoring of nematode communities reveals direct and indirect responses to plant-based manipulations - Robbert van Himbeeck; Sara Giulia Cazzaniga; Sven van den Elsen; Job Oude Vrielink; Semih Karst Aslan; Johnny Visser; Johannes Helder (Soil Biology and Biochemistry, 2024)

The probiotic SLAB51 as agent to counteract BPA toxicity on zebrafish gut microbiota -liver-brain axis - Christian Giommi; Marta Lombó; Hamid R. Habibi; Giacomo Rossi; Danilo Basili; Sara Mangiaterra; Claudia Ladisa; Giulia Chemello; Oliana Carnevali; Francesca Maradonna (Science of The Total Environment, 2024)

Recolonization dynamics of marble monuments after cleaning treatments: A nine-year follow-up study - Georgia Toreno; Laura Zucconi; Giulia Caneva; Paola Meloni; Daniela Isola (Science of The Total Environment, 2024)

Impacts of hydropeaking: A systematic review - Nusrat Jahan Bipa; Giulia Stradiotti; Maurizio Righetti; Giuseppe Roberto Pisaturo (Science of The Total Environment, 2024)

Routes of dispersion of antibiotic resistance genes from the poultry farm system - Daniel Scicchitano; Giulia Babbi; Giorgia Palladino; Silvia Turroni; Yitagele Terefe Mekonnen; Cédric Laczny; Paul Wilmes; Pimlapas Leekitcharoenphon; Andrea Castagnetti; Federica D'Amico; Patrizia Brigidi; Castrense Savojardo; et al. (Science of The Total Environment, 2024)

Diatom and macroinvertebrate communities dynamic: A co-occurrence pattern analysis on plastic substrates - Davide Taurozzi; Giulia Cesarini; Massimiliano Scalici (Science of The Total Environment, 2024)

Embryonic and larval exposure to propylparaben induces developmental and long-term neurotoxicity in zebrafish model - Carmine Merola; Giulia Caioni; Cristiano Bertolucci; Tyrone Lucon-Xiccato; Beste Başak Savaşçı; Sabrina Tait; Marialuisa Casella; Serena Camerini; Elisabetta Benedetti; Monia Perugini (Science of The Total Environment, 2024)

Low prevalence of bacteria harbouring the main transferable genes coding for β-lactams resistance in ovine bulk tank milk produced in Central Italy - Barbara Turchi; Luca Turini; Letizia Tartufoli; Giulia Paolieri; Roberta Mauceri; Francesca Pedonese; Filippo Fratini; Beatrice Torracca; Domenico Cerri; Fabrizio Bertelloni (Small Ruminant Research, 2024)

Assessment of high-enthalpy composite eutectic phase change materials efficiency in asphalt binders for cooling pavements - Jiasheng Dai; Feng Ma; Cesare Sangiorgi; Giulia Tarsi; Zhen Fu; Piergiorgio Tataranni; Chen Li; Yingjie Hou (Journal of Cleaner Production, 2024)

LCA for territorial metabolism analysis: An application to organic waste management planning - Laura Ferretto; Giulia Lucertini; Daniele Brigolin (Journal of Cleaner Production, 2024)

Polycyclic aromatic hydrocarbons in tropical Australian stalagmites: a framework for reconstructing paleofire activity - Elena Argiriadis; Rhawn F. Denniston; Stefania Ondei; David M.J.S. Bowman; Giulia Genuzio; Huong Quynh Anh Nguyen; Jamie Thompson; Mattia Baltieri; Jonathan Azenon; John Cugley; David Woods; William F. Humphreys; et al. (Geochimica et Cosmochimica Acta, 2024)

Sensory properties of foods functionalised with milk proteins - Andrea Balivo; Giulia d’Errico; Alessandro Genovese (Food Hydrocolloids, 2024)

Outcomes of self-control plans on acrylamide levels in processed food - Giulia Rampazzo; Michela Casarotto; Claudia Finotello; Marco Redaelli; Giampiero Pagliuca; Teresa Gazzotti (Food Control, 2024)

Greenness and neuropsychiatric symptoms in dementia - Manuela Tondelli; Annalisa Chiari; Giulia Vinceti; Chiara Galli; Simone Salemme; Tommaso Filippini; Chiara Carbone; Claudia Minafra; Claudia De Luca; Riccardo Prandi; Simona Tondelli; Giovanna Zamboni (Environmental Research, 2024)

Assessment of legacy and alternative halogenated organic pollutants in outdoor dust and soil from e-waste sites in Nigeria: Concentrations, patterns, and implications for human exposure - Bilikis T. Folarin; Giulia Poma; Shanshan Yin; Jorgelina C. Altamirano; Temilola Oluseyi; Gbolahan Badru; Adrian Covaci (Environmental Pollution, 2024)

Unravelling competitive adsorption phenomena in the aqueous phase reforming of carboxylic acids on Pt catalysts: An experimental and theoretical study - Giuseppe Pipitone; Alyssa J.R. Hensley; Ayodeji Omoniyi; Giulia Zoppi; Raffaele Pirone; Samir Bensaid (Chemical Engineering Journal, 2024)

Life cycle assessment of stone consolidants for conservation of cultural heritage - Alessandro Dal Pozzo; Giulia Masi; Enrico Sassoni; Alessandro Tugnoli (Building and Environment, 2024)

Broad-spectrum virucidal activity of a hydroalcoholic extract of grape pomace - Elena Iacono; Carlo Di Marzo; Mauro Di Stasi; Emily Cioni; Francesca Gambineri; Antonella Giuliana Luminare; Marinella De Leo; Alessandra Braca; Paola Quaranta; Michele Lai; Giulia Freer; Mauro Pistello (Bioresource Technology Reports, 2024)

Anti-Candida Antibodies of Patients with Invasive Candidiasis Inhibit Growth, Alter Cell Wall Structure, and Kill Candida albicans In Vitro - Giulia Carrano; Inés Arrieta-Aguirre; Ander Díez; Marta Bregón-Villahoz; Iñigo Fernandez-de-Larrinoa; María-Dolores Moragues (Mycopathologia, 2024)
Invasive candidiasis (IC), caused by Candida yeasts, particularly Candida albicans , poses a significant threat with high mortality rates. Diagnosis is challenging due to Candida 's common presence in human microbiota. To address this, our research group developed an immunofluorescence assay detecting Candida albicans Germ Tube Antibodies (CAGTA) in IC patients. CAGTA, indicative of invasive processes, is associated with a lower mortality rate in ICU patients. Based on this premise, this study aims to provide results regarding the lack of knowledge about the potential activity of CAGTA against invasive infections in humans caused by the fungus Candida albicans . Therefore, in order to characterize the activity of CAGTA produced by patients with IC, we used sera from 29 patients with IC caused by either C. albicans or non- albicans Candida species. Whole serum IgG antibodies were fractionated into anti-blastospores, CAGTA-enriched, and purified CAGTA and the assessments included XTT colorimetric assays for metabolic activity, CFU counts for viability, and microscopy for growth, viability, and morphological analysis. The CAGTA-enriched IgG fraction significantly reduced the metabolic activity and viability of C. albicans compared to anti-blastospores. Purified CAGTA altered germ tube cell wall surfaces, as revealed by electron microscopy, and exhibited fungicidal properties by DiBAC fluorescent staining. In conclusion, antibodies in response to invasive candidiasis have antifungal activity against Candida albicans , influencing metabolic activity, viability, and cell wall structure, leading to cell death. These findings suggest the potential utility of CAGTA as diagnostic markers and support the possibility of developing immunization protocols against Candida infections.

Crawl away from the light! Assessing behavioral and physiological photoprotective mechanisms in tropical solar-powered sea slugs exposed to natural light intensities - Laia Burgués Palau; Giulia Senna; Elise M. J. Laetz (Marine Biology, 2024)
Photosynthesizers face a trade-off regarding light: they need enough to maintain high photosynthetic rates, yet excess leads to oxidative stress. Despite this, light and its detrimental effects are chronically underestimated. Solar-powered sea slugs (Sacoglossa: Gastropoda) provide the ideal lens with which to study this trade-off, since they steal chloroplasts from algae but do not inherit photoacclimation and photorepair capacities. We collected three slug species in Curaçao during March and December 2022, comparing the amount of light they received in nature to their optimal light intensities for photosynthesis, and their preferred light intensities. We then investigated behavioral and physiological photoprotection mechanisms to determine if and how they limit light. Finally, we examined oxidative activity under optimal and excess light. All three species were naturally exposed to more light (> 1000 µmol m −2 s −1 ) than is optimal or preferred. Elysia crispata (kleptoplast retention for > 3 months) is fully exposed to light in nature but reduces the light reaching its kleptoplasts via parapodial shading. Elysia velutinus retains kleptoplasts for ~ 2 weeks and hides in its macroalgal food, limiting light exposure. Both species displayed low amounts of oxidative activity under optimal light, which increased slightly under excess light. Elysia ornata retained chloroplasts for ~ 3 days, lacked observable photoprotection and always displayed high levels of oxidative activity, potentially explaining its limited capacity for kleptoplast retention. Furthermore, both E. velutinus and E. ornata display strong light-avoidance behaviors. This study clearly demonstrates links between high light intensities, photoprotection, and oxidative stress, highlighting the need for future studies that examine aquatic photosynthesizers under natural lighting.

What’s in the bee nest holes? A single aggregation of Megachile parietina reveals and helps to fill up Eltonian shortfalls - Elisa Monterastelli; Alfonso Orlotti; Giulia Calderai; Chiara Natali; Marta Mariotti Lippi; Claudio Ciofi; Alessandro Cini; Leonardo Dapporto; Marino Quaranta; Francesca Romana Dani (Journal of Insect Conservation, 2024)
Megachile (Chalicodoma) parietina (Geoffroy, 1785) is a Palearctic solitary bee included in the Red List of some central European Countries. Females build durable nests, reused year after year, by mixing soil with a salivary secretion. Like for most solitary bees, the resources contained within M. parietina nests attract several other insects which exploit pollen supplies or feed on the immature brood. These associated insects have mainly been studied for mantained bees and considered for their effect on the host reproductive success. A very large nesting aggregation of M. parietina in Central Tuscany has been studied for three consecutive years. We have identified 32 associated insect species, which certainly are an underestimate of the species present. Among the identified species, only eight had been previously reported for M. parietina . All the species were classified both according to the specificity for the host taxon ( Chalicodoma , Megachilidae, Anthophila, Hymenoptera, Others) and to the ecological relationship (cleptoparasites, parasitoids, predators of larvae, food commensal, scavengers, and occasional nest users). This highlighted both the richness of the ecological network within the nesting aggregation and the value of studying these nesting sites to fill Eltonian shortfalls, i.e. the deficiency in ecology knowledge, of bees and their associated fauna. Implications for insect conservation. We suggest that, besides their role in pollination, large and stable bee nesting sites increase the local insect biodiversity, and that attention should be paid to their conservation within actions aimed to support populations of wild pollinators.

Microbiome dynamics of soils covered by plastic and bioplastic mulches - Giorgia Santini; Maraike Probst; María Gómez-Brandón; Carla Manfredi; Maria Teresa Ceccherini; Giacomo Pietramellara; Lucia Santorufo; Giulia Maisto (Biology and Fertility of Soils, 2024)
In recent decades, the use of plastic mulch in agriculture has largely increased to meet the growing demand for food. Despite their potential benefits, it is still unknown the long-term impact of mulches on soil microbiome. In this study, we compared at a mesocosm level the effects of polyethylene (Plastic) and Mater-bi® (Bioplastic) mulches on the soil physico-chemical (i.e., pH, soil water content, Fourier transform infrared-attenuated total reflection-FTIR), microbiological, and biochemical (i.e., microbial respiration, enzymatic activities, abundances and composition of bacterial, fungal and microarthropod communities) properties after 6 and 12 months. The analysis of the microbiome revealed an increase in bacterial richness and diversity in the 12-month-treated bioplastic soils. Members of Solirubrobacterales , Vicinamibacterales , Nitrososphaerales , Crenarchaeota , and Clostridiales were the most abundant following the bioplastic treatment. While the fungal and microarthropod communities varied over time, neither of them was affected by the type of mulching. Further longer-term research is needed to clarify the impact of bioplastic and plastic mulches on the soil microbiome, including microarthropods, and its dynamics over time.

Virulence evaluation of Israeli Marek’s disease virus isolates from commercial poultry using their meq gene sequence - Irit Davidson; Caterina Lupini; Elena Catelli; Giulia Quaglia; Luca Maddaloni; Giulia Mescolini (Virus Genes, 2024)

Higher soil moisture increases microclimate temperature buffering in temperate broadleaf forests - Caroline Greiser; Lucia Hederová; Giulia Vico; Jan Wild; Martin Macek; Martin Kopecký (Agricultural and Forest Meteorology, 2024)

Spicy food for the egg-cowries: the evolution of corallivory in the Ovulidae (Gastropoda: Cypraeoidea) - Elisa Nocella; Sofya Sergeevna Zvonareva; Giulia Fassio; Daniela Pica; Barbara Buge; Raimondo Villa; Nicolas Puillandre; Maria Vittoria Modica; Marco Oliverio (Frontiers in Marine Science, 2024)
Introduction Host-parasite associations provide very useful models to study adaptive processes. We investigated the interaction between carnivorous marine gastropods, the Ovulidae or egg-cowries, and their cnidarian food targets. Ovulidae (Fleming, 1828), is a family of specialized carnivorous caenogastropods that feed by browsing on octocorals (Anthozoa: Octocorallia: Malacalcyonacea and Scleralcyonacea) or, to a much lesser degree, on antipatharians (Anthozoa: Hexacorallia: Antipatharia) and Stylasteridae (Hydrozoa: Hydroidolina: Anthoathecata). Very scanty information is available on the phylogenetic relationships and the degree of specificity of the relationship with the cnidarians of this corallivorous lineage, especially for deep-water taxa. Methods To assess taxonomic identifications and investigate cnidarian/ovulid relationships in the context of their evolution, we generated an extensive molecular dataset comprising two mitochondrial ( cox1 and 16S rDNA ) and one nuclear gene ( 28S rDNA ) from 524 specimens collected worldwide. The coral hosts of the ovulid species have been identified by integrating literature data with new records, employing morphological and/or molecular (the mitochondrial 16S rDNA and mtMSH , and the nuclear ITS2) markers. Results We obtained a molecular phylogenetic framework for the Ovulidae, time-calibrated with nine reliable fossil records. An ancestral state reconstruction allowed to identify Hexacorallia or Hydroidolina as the most likely ancestral cnidarian host for the Ovulidae. Discussion Our phylogenetic hypothesis revealed the existence of groups that do not completely correspond to the currently employed subfamilial arrangement. Concerning trophic ecology, while only pediculariines ( Pedicularia and allied) are associated with hydrozoans (Stylasteridae), our results suggest that some ovulid lineages shifted independently between octocorals and hexacorals.

The chemical composition of the aerial parts essential oil of Lonas annua (L.) Vines & Druce (Asteraceae) - Alessandro Vaglica; Giulia D’Agostino; Giuseppe Bazan; Maurizio Bruno (Natural Product Research, 2024)

The chemical composition of the aerial parts essential oil of Ammi crinitum Guss. (Apiaceae) endemic of Sicily (Italy) - Giulia D’Agostino; Adele Cicio; Alessandro Vaglica; Vincenzo Ilardi; Maurizio Bruno (Natural Product Research, 2024)

A risk assessment for the remote ocean: the case of the South East Atlantic - Holly J. Niner; Siân E. Rees; Giulia La Bianca; Kirsty A. McQuaid; Kerry L. Howell (Frontiers in Marine Science, 2024)
Degradation of the natural world and associated ecosystem services is attributed to a historical failure to include its ‘value’ in decision-making. Uncertainty in the quantification of the relationship between natural capital ‘assets’ that give rise to critical societal benefits and people is one reason for the omission of these values from natural resource management. As this uncertainty increases in marine systems and further still with distance from the coast, the connection between society and natural capital assets is less likely to be included adequately in decision-making. Natural capital assets of Areas Beyond National Jurisdiction (ABNJ), including those of the deep sea, are distant but are known to generate many benefits for society, from the diffuse and broad-scale benefits of climate regulation to the provision of wild fish for food. While our understanding of the precise relationships (the status of asset stocks, ecosystem functions and processes) that control the availability of ecosystem services and the flows of benefits is limited, this does not preclude opening a discourse on how these natural capital assets could best be managed to continue to benefit society. Here we apply a natural capital approach to the South East Atlantic ABNJ, one of the least scientifically understood regions of the planet, and develop a framework for risk assessment. We do this by describing the benefit flows from the natural capital assets of the region, appraising how activities are creating pressures on these flows and whether the controls for these pressures protect them. Our risk register highlights how governance currently favours the protection of direct (extractive) benefit flows from natural capital assets of the region, which are primarily targeted for financial benefit. Without a systems-based framework that can account for the cumulative pressures on natural capital assets their status, associated ecosystem services and benefits are at risk. Such an approach is essential to capture and protect the foundational and often diffuse connections between marine natural capital and global society.

Spatial analysis of demersal food webs through integration of eDNA metabarcoding with fishing activities - Davide Cicala; Giulia Maiello; Fabio Fiorentino; Germana Garofalo; Daniela Massi; Alice Sbrana; Stefano Mariani; Simone D’Alessandro; Matteo Stefani; Lucie Perrodin; Tommaso Russo (Frontiers in Marine Science, 2024)
The evaluation of the status of marine communities, and especially the monitoring of those heavily exploited by fisheries, is a key, challenging task in marine sciences. Fishing activities are a major source of disruption to marine food webs, both directly, by selectively removing components at specific trophic levels (TL), and indirectly, by altering habitats and production cycles. Food web analysis can be very useful in the context of an Ecosystem Approach to Fisheries, but food web reconstructions demand large and expensive data sets, which are typically available only for a small fraction of marine ecosystems. Recently, new technologies have been developed to easily, quickly and cost-effectively collect environmental DNA (eDNA) during fishing activities. By generating large, multi-marker metabarcoding data from eDNA samples obtained from commercial trawlers, it is possible to produce exhaustive taxonomic inventories for the exploited ecosystems, which are suitable for food-web reconstructions. Here, we integrate and re-analyse the data of a recent study in which the α diversity was investigated using the eDNA opportunistically collected during fishing operations. Indeed, we collect highly resolved information on species feeding relationships to reconstruct the food webs at different sites in the Strait of Sicily (Mediterranean Sea) from eDNA and catch data. After observing that the trophic networks obtained from eDNA metabarcoding data are more consistent with the available knowledge, a set of food web indicators (species richness, number of links, direct connectance and generality) is computed and analysed to unravel differences in food webs structure through different areas (spatial variations). Species richness, number of links and generality (positively) and direct connectance (negatively) are correlated with increasing distance from the coast and fishing effort intensity. The combined effects of environmental gradients and fishing effort on food web structure at different study sites are then examined and modelled. Taken together, these findings indicate the suitability of eDNA metabarcoding to assist and food web analysis, obtain several food web-related ecological indicators, and tease out the effect of fishing intensity from the environmental gradients of marine ecosystems.

Phytochemical characterization and biological activities of Stenomesson miniatum bulb extract, a medicinal plant of the Andes - Mariacaterina Lianza; Carmela Fimognari; Jean-Marc Nuzillard; Ferruccio Poli; Jean-Hugues Renault; Francesca Bonvicini; Giulia Greco; Eleonora Turrini (Plant Biosystems, 2024)

Occurrence and patterns of metals in mangrove forests from the Oman Sea, Iran - Reza Dahmardeh Behrooz; Sanaz Khammar; Giulia Poma; Fatemeh Rajaei (Marine Pollution Bulletin, 2024)

Identification and quantification of polystyrene microplastics in marine sediments facing a river mouth through NMR spectroscopy - Giulia Papini; Greta Petrella; Daniel Oscar Cicero; Clara Boglione; Arnold Rakaj (Marine Pollution Bulletin, 2024)

Spatio-temporal variations of growth, chemical composition, and gene expression in Mediterranean mussels (Mytilus galloprovincialis): A two-year study in the Venice lagoon under anthropogenic and climate changing scenarios - Francesco Bordignon; Camilla Bertolini; Ilaria Bernardini; Giulia Dalla Rovere; Silvia Iori; Cristina Breggion; Roberto Pastres; Luciano Boffo; Gerolamo Xiccato; Valerio Matozzo; Jacopo Fabrello; Davide Asnicar; et al. (Aquaculture, 2024)

Hermetia illucens larvae meal as an alternative protein source in practical diets for gilthead sea bream (Sparus aurata): A study on growth, plasma biochemistry and gut microbiota - Serena Busti; Alessio Bonaldo; Marco Candela; Daniel Scicchitano; Giulia Trapella; Fabio Brambilla; Côme Guidou; Christophe Trespeuch; Federico Sirri; Francesco Dondi; Pier Paolo Gatta; Luca Parma (Aquaculture, 2024)

Air pollution and oxidative stress in adults suffering from airway diseases. Insights from the Gene Environment Interactions in Respiratory Diseases (GEIRD) multi-case control study - Giulia Squillacioti; Valeria Bellisario; Federica Ghelli; Alessandro Marcon; Pierpaolo Marchetti; Angelo G. Corsico; Pietro Pirina; Sara Maio; Massimo Stafoggia; Giuseppe Verlato; Roberto Bono (Science of The Total Environment, 2024)

Incomplete sanitation in the Metropolitan Region of São Paulo results in detection of SARS-CoV-2 in headwater streams - Ricardo H. Taniwaki; Rodrigo F. Bueno; Giulia B.S. Bispo; Matheus R. Augusto; Guilherme S. Souza; Bruna Chyoshi; Roseli F. Benassi; Nelson Gouveia; Lívia M.B. Camilo; Adriana F.A. Duran; Luís C. Schiesari (Science of The Total Environment, 2024)

An Arctic natural oil seep investigated from space to the seafloor - Giuliana Panieri; Claudio Argentino; Sofia P. Ramalho; Francesca Vulcano; Alessandra Savini; Luca Fallati; Trond Brekke; Giulia Galimberti; Federica Riva; João Balsa; Mari H. Eilertsen; Runar Stokke; et al. (Science of The Total Environment, 2024)

A PM10 chemically characterized nation-wide dataset for Italy. Geographical influence on urban air pollution and source apportionment - Adriana Pietrodangelo; Maria Chiara Bove; Alice Corina Forello; Federica Crova; Alessandro Bigi; Erika Brattich; Angelo Riccio; Silvia Becagli; Stefano Bertinetti; Giulia Calzolai; Silvia Canepari; David Cappelletti; et al. (Science of The Total Environment, 2024)

Ocean warming and acidification detrimentally affect coral tissue regeneration at a Mediterranean CO2 vent - Teresa Sani; Fiorella Prada; Giulia Radi; Erik Caroselli; Giuseppe Falini; Zvy Dubinsky; Stefano Goffredo (Science of The Total Environment, 2024)

Modelling micropollutant cycle in Lake Como in a winter scenario: Implications for water use and reuse, ecosystem services, and the EU zero pollution action plan - Antonio Di Guardo; Sara Castiglioni; Isabella Gambino; Alessia Sailis; Giulia Salmoiraghi; Silvia Schiarea; Marco Vighi; Elisa Terzaghi (Science of The Total Environment, 2024)

The application of biosecurity practices for preventing avian influenza in North-Eastern Italy turkey farms: An analysis of the point of view and perception of farmers - Stefania Crovato; Alessio Menini; Paolo Mulatti; Tiziano Dorotea; Anna Rosa Favretto; Francesca Zaltron; Giulia Mascarello; Giandomenico Pozza (Preventive Veterinary Medicine, 2024)

Barnacle-rich facies as a tool for palaeoenvironmental reconstructions - Giovanni Coletti; Giulia Bosio; Alberto Collareta; Or Mordecai Bialik; Eleonora Regattieri; Irene Cornacchia; Gianni Insacco; John Buckeridge (Palaeogeography, Palaeoclimatology, Palaeoecology, 2024)

A physical/statistical data-fusion for the dynamical downscaling of GRACE data at daily and 1 km resolution - Victor Pellet; Filipe Aires; Lorenzo Alfieri; Giulia Bruno (Journal of Hydrology, 2024)

Effect of design and molecular interactions on the food preserving properties of alginate/pullulan edible films loaded with grape pomace extract - Giulia Mugnaini; Massimo Bonini; Luigi Gentile; Olimpia Panza; Matteo Alessandro Del Nobile; Amalia Conte; Rodolfo Esposito; Gerardino D'Errico; Federica Moccia; Lucia Panzella (Journal of Food Engineering, 2024)

Corrigendum to “From farm to fork: Spread of a multidrug resistant Salmonella Infantis clone encoding blaCTX-M-1 on pESI-like plasmids in Central Italy” [Int. J. Food Microbiol. volume 410 (2024) 1–11/110490] - Ilaria Russo; Jennie Fischer; Laura Uelze; Maira Napoleoni; Giuditta Fiorella Schiavano; Francesca Andreoni; Giorgio Brandi; Giulia Amagliani (International Journal of Food Microbiology, 2024)

From farm to fork: Spread of a multidrug resistant Salmonella Infantis clone encoding blaCTX-M-1 on pESI-like plasmids in Central Italy - Ilaria Russo; Jennie Fischer; Laura Uelze; Maira Napoleoni; Giuditta Fiorella Schiavano; Francesca Andreoni; Giorgio Brandi; Giulia Amagliani (International Journal of Food Microbiology, 2024)

Companilactobacillus alimentarius: An extensive characterization of strains isolated from spontaneous fermented sausages - Giulia Tabanelli; Federica Barbieri; Alberto Baños; Jose Manuel Garcia Madero; Mireya Viviana Belloso Daza; Claudia Cortimiglia; Giovanni Milani; Daniela Bassi; Fausto Gardini; Chiara Montanari (International Journal of Food Microbiology, 2024)

A systematic review on the occurrence of Salmonella in farmed Tenebrio molitor and Acheta domesticus or their derived products - Filippo Marzoli; Michela Bertola; Juliane Pinarelli Fazion; Giulia Cento; Pietro Antonelli; Beatrice Dolzan; Lisa Barco; Simone Belluco (International Journal of Food Microbiology, 2024)

HBM4EU e-waste study: Occupational exposure of electronic waste workers to phthalates and DINCH in Europe - Paulien Cleys; Emilie Hardy; Yu Ait Bamai; Giulia Poma; Adam Cseresznye; Govindan Malarvannan; Paul T.J. Scheepers; Susana Viegas; Simo P. Porras; Tiina Santonen; Lode Godderis; Jelle Verdonck; et al. (International Journal of Hygiene and Environmental Health, 2024)

Centimetric circular areas uncolonized by microbial biofilms (CUMBs) on marble surfaces and insights on a lichen-related origin - Marta Cicardi; Davide Bernasconi; Luca Martire; Linda Pastero; Giulia Caneva; Sergio E. Favero-Longo (International Biodeterioration & Biodegradation, 2024)

A fluvial record of late Quaternary climate changes and tectonic uplift along the Marche Piedmont Zone of the Apennines: New insights from the Tesino River (Italy) - Michele Delchiaro; Giulia Iacobucci; Marta Della Seta; Natacha Gribenski; Daniela Piacentini; Valeria Ruscitto; Marta Zocchi; Francesco Troiani (Geomorphology, 2024)

Modeling post-fire regeneration patterns under different restoration scenarios to improve forest recovery in degraded ecosystems - Giulia Mantero; Nicolò Anselmetto; Donato Morresi; Fabio Meloni; Paola Bolzon; Emanuele Lingua; Matteo Garbarino; Raffaella Marzano (Forest Ecology and Management, 2024)

Development of innovative antioxidant food packaging systems based on natural extracts from food industry waste and Moringa oleifera leaves - Giulia Barzan; Alessio Sacco; Andrea Mario Giovannozzi; Chiara Portesi; Consolato Schiavone; Jesús Salafranca; Magdalena Wrona; Cristina Nerín; Andrea Mario Rossi (Food Chemistry, 2024)

The local environment and germline genetic variation predict cancer risk in the UK Biobank prospective cohort - Alessio Felici; Giulia Peduzzi; Francesca Giorgolo; Andrea Spinelli; Marco Calderisi; Anna Monreale; Riccardo Farinella; Roberto Pellungrini; Federico Canzian; Daniele Campa (Environmental Research, 2024)

Exploring adaptive strategies to cope with climate change: The case study of Le Corbusier's Modern Architecture retrofitting - Giulia Lamberti; Francesca Contrada; Andrea Kindinis (Energy and Buildings, 2024)

Assessing the role of atmospheric dispersion vs. emission strength in the southern Po Valley (Italy) using dispersion-normalised multi-time receptor modelling - Federica Crova; Alice Corina Forello; Vera Bernardoni; Giulia Calzolai; Silvia Canepari; Stefania Argentini; Francesca Costabile; Maria Agostina Frezzini; Fabio Giardi; Franco Lucarelli; Dario Massabò; Lorenzo Massimi; et al. (Atmospheric Environment, 2024)

The effects of virtual reality environmental enrichments on craving to food in healthy volunteers - Giulia Benvegnù; Alessandro Piva; Camilla Cadorin; Vanessa Mannari; Matteo Girondini; Angela Federico; Stefano Tamburin; Cristiano Chiamulera (Psychopharmacology, 2024)
Rationale Environmental enrichment (EE) is a non-pharmacological approach that has been shown to be effective in reducing food-taking in rats. Studies in human volunteers are still in their infancy, given the difficulty to translate the complexity of EE in clinical practice. Virtual reality (VR) is a promising methodological approach, but no study has yet applied it to model and test EE in humans. Objectives The present study is the first to assess the effects of virtual EE on craving for palatable food. Methods Eighty-one healthy volunteers (43 women) were divided into three groups: (i) exposure to a virtual EE (VR-EE), (ii) exposure to a virtual neutral environment (VR-NoEE), and (iii) without exposure to VR (No VR). Craving for palatable food at basal level and evoked by neutral and palatable food images was assessed before and after the VR simulation. Behavior during VR exposure and subjective measures related to the experience were also collected. Results VR-EE group showed a significantly greater decrease in pre-post craving difference compared to No VR for all assessments and at basal level compared to VR-NoEE. Interestingly, an inverse correlation between craving and deambulation in the VR simulation emerged in VR-EE group only. Conclusions The study highlighted the feasibility of exposing human subjects to an EE as a virtual simulation. Virtual EE induced effects on basal craving for food that suggest the potential for further improvements of the protocol to extend its efficacy to palatable food cues.

Resilience of Xanthoria parietina under Mars-like conditions: photosynthesis and oxidative stress response - Christian Lorenz; Carmen Arena; Ermenegilda Vitale; Elisabetta Bianchi; Giovanni Poggiali; Giulia Alemanno; Renato Benesperi; John Robert Brucato; Stephen Garland; Jörn Helbert; Stefano Loppi; Andreas Lorek; et al. (Planta, 2024)

Perennial intermediate wheatgrass accumulates more soil organic carbon than annual winter wheat – a model assessment - Fiona H. M. Tang; Timothy E. Crews; Nathaniel A. Brunsell; Giulia Vico (Plant and Soil, 2024)
Purpose Perennial crops have been suggested as a more sustainable alternative to the currently most common cropping systems. Compared with annual plants, perennial plants produce more biomass and have deeper roots, and are expected to lead to higher soil organic carbon (SOC). This hypothesis, however, has not been well tested for grain crops. Methods Using perennial intermediate wheatgrass (IWG, Thinopyrum intermedium ) and annual winter wheat ( Triticum aestivum ) as focal species, and native grassland as reference, we quantified the SOC accumulation via a process-based model, describing water and heat exchanges and carbon-nitrogen cycling in the canopy and soil to a depth of 2 m. The model includes C fixation via photosynthesis, plant biomass growth and litter production, physical protection of SOC, depolymerisation, C mineralisation, nitrification, denitrification, microbial growth, and necromass turnover in the soil. While of general applicability, we considered a sandy loam under warm-summer humid continental climate. Results Following a conversion from native grassland, IWG reduced SOC losses by at least 38%, especially in the particulate organic carbon (POC) pool, within the top 2 m of soil, compared with annual wheat. Soil microbial biomass and soil respiration were higher in IWG than annual wheat. Shifting from annual wheat to high photosynthetic capacity IWG increased SOC by about 33 g C m −2 y −1 (averaged over a 4-year continuous IWG cropping), with a large fraction of SOC gain stemming from restoring POC. Conclusion Compared with annual grains, perennial grains can increase soil carbon sequestration and maintain SOC at levels nearer to that of native grasslands.

Urethane dimethacrylate-based photopolymerizable resins for stereolithography 3D printing: A physicochemical characterisation and biocompatibility evaluation - Giulia Pitzanti; Valentyn Mohylyuk; Francesca Corduas; Niall M. Byrne; Jonathan A. Coulter; Dimitrios A. Lamprou (Drug Delivery and Translational Research, 2024)
Vat photopolymerisation (VP) three-dimensional printing (3DP) has attracted great attention in many different fields, such as electronics, pharmaceuticals, biomedical devices and tissue engineering. Due to the low availability of biocompatible photocurable resins, its application in the healthcare sector is still limited. In this work, we formulate photocurable resins based on urethane dimethacrylate (UDMA) combined with three different difunctional methacrylic diluents named ethylene glycol dimethacrylate (EGDMA), di(ethylene glycol) dimethacrylate (DEGDMA) or tri(ethylene glycol) dimethacrylate (TEGDMA). The resins were tested for viscosity, thermal behaviour and printability. After printing, the 3D printed specimens were measured with a digital calliper in order to investigate their accuracy to the digital model and tested with FT-IR, TGA and DSC. Their mechanical properties, contact angle, water sorption and biocompatibility were also evaluated. The photopolymerizable formulations investigated in this work achieved promising properties so as to be suitable for tissue engineering and other biomedical applications. Graphical abstract

Groundwater is a hidden global keystone ecosystem - Mattia Saccò; Stefano Mammola; Florian Altermatt; Roman Alther; Rossano Bolpagni; Anton Brancelj; David Brankovits; Cene Fišer; Vasilis Gerovasileiou; Christian Griebler; Simone Guareschi; Grant C. Hose; et al. (Global Change Biology, 2024)
Groundwater is a vital ecosystem of the global water cycle, hosting unique biodiversity and providing essential services to societies. Despite being the largest unfrozen freshwater resource, in a period of depletion by extraction and pollution, groundwater environments have been repeatedly overlooked in global biodiversity conservation agendas. Disregarding the importance of groundwater as an ecosystem ignores its critical role in preserving surface biomes. To foster timely global conservation of groundwater, we propose elevating the concept of keystone species into the realm of ecosystems, claiming groundwater as a keystone ecosystem that influences the integrity of many dependent ecosystems. Our global analysis shows that over half of land surface areas (52.6%) has a medium‐to‐high interaction with groundwater, reaching up to 74.9% when deserts and high mountains are excluded. We postulate that the intrinsic transboundary features of groundwater are critical for shifting perspectives towards more holistic approaches in aquatic ecology and beyond. Furthermore, we propose eight key themes to develop a science‐policy integrated groundwater conservation agenda. Given ecosystems above and below the ground intersect at many levels, considering groundwater as an essential component of planetary health is pivotal to reduce biodiversity loss and buffer against climate change.

Essential omega‐3 fatty acids are depleted in sea ice and pelagic algae of the Central Arctic Ocean - Katrin Schmidt; Martin Graeve; Clara J. M. Hoppe; Sinhué Torres‐Valdes; Nahid Welteke; Laura M. Whitmore; Philipp Anhaus; Angus Atkinson; Simon T. Belt; Tina Brenneis; Robert G. Campbell; Giulia Castellani; et al. (Global Change Biology, 2024)
Microalgae are the main source of the omega‐3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), essential for the healthy development of most marine and terrestrial fauna including humans. Inverse correlations of algal EPA and DHA proportions (% of total fatty acids) with temperature have led to suggestions of a warming‐induced decline in the global production of these biomolecules and an enhanced importance of high latitude organisms for their provision. The cold Arctic Ocean is a potential hotspot of EPA and DHA production, but consequences of global warming are unknown. Here, we combine a full‐seasonal EPA and DHA dataset from the Central Arctic Ocean (CAO), with results from 13 previous field studies and 32 cultured algal strains to examine five potential climate change effects; ice algae loss, community shifts, increase in light, nutrients, and temperature. The algal EPA and DHA proportions were lower in the ice‐covered CAO than in warmer peripheral shelf seas, which indicates that the paradigm of an inverse correlation of EPA and DHA proportions with temperature may not hold in the Arctic. We found no systematic differences in the summed EPA and DHA proportions of sea ice versus pelagic algae, and in diatoms versus non‐diatoms. Overall, the algal EPA and DHA proportions varied up to four‐fold seasonally and 10‐fold regionally, pointing to strong light and nutrient limitations in the CAO. Where these limitations ease in a warming Arctic, EPA and DHA proportions are likely to increase alongside increasing primary production, with nutritional benefits for a non‐ice‐associated food web.

Two new species of Atopobathynella (Parabathynellidae, Bathynellacea) from the Pilbara region, Australia - Giulia Perina; Ana I. Camacho; Melissa Danks; Nicole White; Michelle T. Guzik (Systematics and Biodiversity, 2023)

An integrated approach to explore the monophyletic status of the cosmopolitan genus Hexabathynella (Crustacea, Bathynellacea, Parabathynellidae): two new species from Rottnest Island (Wadjemup), Western Australia - Giulia Perina; Ana Camacho; Steven J.B. Cooper; Stephanie Floeckner; Alison J. Blyth; Mattia Saccò (Systematics and Biodiversity, 2023)

Taphonomy of a Mysticete Whale from the Lower Pliocene of the Coast of Cádiz (Spain) - Giulia Bosio; Ildefonso Bajo-Campos; Alberto Collareta; Sergio Ros-Montoya; Daniel de la Torre; Giovanni Coletti; Giovanni Bianucci (Journal of Marine Science and Engineering, 2023)
A fossil mysticete was discovered along the southwestern coast of Spain, occurring in a block detached from the Neogene deposits exposed along a coastal cliff at the locality of Conil de la Frontera (Cádiz, Spain). These deposits range from Pliocene to Pleistocene in age and include shallow-marine, mixed carbonate–siliciclastic sediments, with the whale being found in occurrence of a stratigraphic unconformity marked by Thalassinoides burrows. 87Sr/86Sr analyses on oyster shells associated with the skeleton suggest an Early Pliocene age, in agreement with the age of the lowermost unit cropping out at the study site. The studied cetacean specimen consists of an articulated, almost complete balaenopteroid skeleton exposed in the field dorsal side up; being contained in an upside-down block, however, it is preserved in ventral disposition. Bones exhibit a low degree of preservation of the cortical bone tissue, which locally features shark bite marks and Osedax traces as well as abundant encrustations of barnacles and ostreids. Two shark teeth were also found near the skeleton. Bones have preserved their main histological features, even though they locally exhibit microcracks, dissolution, substitution by Fe oxides, and microborings. Sediment particles and late diagenetic cements fill the medullary cavities. We propose that the whale carcass experienced refloating before sinking to the seafloor and that the skeleton was probably exposed on the seafloor for some time before being eventually buried.

Sample contamination explains evidence of close kin proximity in yellowfin tuna (Thunnus albacares) in the Western and Central Pacific Ocean - Giulia Anderson; Jed I. Macdonald; Monal Lal; John Hampton; Neville Smith; Ciro Rico (Frontiers in Marine Science, 2023)
Anderson et al.’s 2019 paper ‘Close Kin Proximity in Yellowfin Tuna ( Thunnus albacares ) as a Driver of Population Genetic Structure in the Tropical Western and Central Pacific’ provided observations of genetically related individuals among sampled yellowfin tuna. Resampling of some individuals from the original study produced very different sequencing results when compared with the original dataset, one possible explanation of which is cross-contamination among the original samples. Re-analyses produced no indication of strong population structure, including a very slightly and consistent heterozygosity deficit with only one statistically significant pairwise F ST value of 0.002. We identified only one pair of genetically similar individuals that could still be an artefact of lingering contamination. These new results therefore support a highly connected population of yellowfin tuna in the study area, although we do not rule out the potential for local adaptation driven by non-observed loci or genetic sub-structure operating at more contemporary scales.

Small Microplastics: A yet Unknown Threat in the Svalbard (Norway) Region - Gabriella Caruso; Valentina Iannilli; Giulia Vitale; Massimiliano Vardè; Marco Oliverio; Sara Bogialli; Lucio Litti; Andrea Setini; Beatrice Rosso; Fabiana Corami (Journal of Marine Science and Engineering, 2023)
The Arctic Ocean is undergoing several transformations because of global climate change. Small microplastics (SMPs) or nanoplastics (NPs) carried by marine aerosols may settle in the land ice and be released to the waters, produced following its melting. As sea ice extent reduces and shipping and fishing activities increase, microplastics (MPs) may enter the region following ocean and maritime transports, with implications on Arctic biota, human health, and socioeconomic issues related to the exploitation of marine resources. First analyses on amphipods collected in Ny-Ålesund confirmed the presence of SMPs. Nevertheless, the threat posed by SMPs/NPs to polar biota and regional human health is not fully understood. This article addresses this issue and the need for organisms as potential bioindicators of plastic pollution, which is currently being carried out in the Svalbard region under the framework of the MICROTRACER project funded by the Italian Arctic Research Program (PRA, Call 2021). The outputs of this research are expected to contribute to deepening the current knowledge of SMPs in Svalbard, providing new insights on their occurrence, distribution, and transfer through the marine trophic web, to realize effective control and regulatory framework measures to implement an integrated multidisciplinary approach for monitoring and to reduce MPs pollution in this fragile polar environment.

The morsel suppliers are gone: local extinction of a mutualistic interaction between birds and capybaras - Ivan Sazima; Juliana Vaz Hipolito; Giulia B. D’Angelo (Ornithology Research, 2023)

Nitrogen-cycling genes in oyster reefs and surrounding sediments: Relationships with environmental factors and respective nitrogen rates - Giulia Filippini; Ana B. Bugnot; Deepa R. Varkey; Nachshon Siboni; Angus Ferguson; Paul E. Gribben; Katherine Erickson; Julia Palmer; Katherine A. Dafforn (Marine Pollution Bulletin, 2023)

Candidate biomarkers of antibiotic resistance for the monitoring of wastewater and the downstream environment - A. Margarida Teixeira; Ivone Vaz-Moreira; David Calderón-Franco; David Weissbrodt; Sabina Purkrtova; Stanislav Gajdos; Giulia Dottorini; Per Halkjær Nielsen; Leron Khalifa; Eddie Cytryn; Jan Bartacek; Célia M. Manaia (Water Research, 2023)

Does a zero-waste strategy in sustainable urban waste management affect hierarchy targets and costs? - Giulia Romano; Lucio Masserini (Utilities Policy, 2023)

Life cycle assessment of chemical synthesis of genistein and its glucosyl derivatives to be employed in the modulation of angiogenesis of hepatocellular cancer - Chiara Ruini; Luca Rigamonti; Aldo Zanni; Giulia Bertani; Gianluca Carnevale; Erika Ferrari; Paolo Neri; Anna Maria Ferrari; Roberto Rosa (Sustainable Chemistry and Pharmacy, 2023)

Environmentally relevant concentrations of triclocarban affect behaviour, learning, and brain gene expression in fish - Tyrone Lucon-Xiccato; Beste Başak Savaşçı; Carmine Merola; Elisabetta Benedetti; Giulia Caioni; Valbona Aliko; Cristiano Bertolucci; Monia Perugini (Science of The Total Environment, 2023)

Wastewater-based epidemiology revealed in advance the increase of enterovirus circulation during the Covid-19 pandemic - Laura Pellegrinelli; Cristina Galli; Arlinda Seiti; Valeria Primache; Aurora Hirvonen; Silvia Schiarea; Giulia Salmoiraghi; Sara Castiglioni; Emanuela Ammoni; Danilo Cereda; Sandro Binda; Elena Pariani (Science of The Total Environment, 2023)

Antidepressants and their metabolites primarily affect lysosomal functions in the marine mussel, Mytilus galloprovincialis - Ayesha Rafiq; Marco Capolupo; Giulia Addesse; Paola Valbonesi; Elena Fabbri (Science of The Total Environment, 2023)

Marine sponges as bioindicators of pollution by synthetic microfibers in Antarctica - Andrea Corti; Giulia Pagano; Angelina Lo Giudice; Maria Papale; Carmen Rizzo; Maurizio Azzaro; Virginia Vinciguerra; Valter Castelvetro; Stefania Giannarelli (Science of The Total Environment, 2023)

Long-term ecological successions of vegetation around Lake Victoria (East Africa) in response to latest Pleistocene and Early Holocene climatic changes - Yunuén Temoltzin-Loranca; Erika Gobet; Boris Vannière; Jacqueline F.N. van Leeuwen; Giulia Wienhues; Colin Courtney-Mustaphi; Mary Kishe; Moritz Muschick; Leighton King; Pavani Misra; Nare Ngoepe; Blake Matthews; et al. (Palaeogeography, Palaeoclimatology, Palaeoecology, 2023)

WITHDRAWN: Corrigendum to “In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice” NeuroToxicology 83 (2021) 1–13 - Giulia Costa; Stefan Spulber; Elena Paci; Maria Antonietta Casu; Sandra Ceccatelli; Nicola Simola; Micaela Morelli (NeuroToxicology, 2023)

Removal of hexavalent chromium using zero-valent magnesium in a continuous flow system - Giulia Maria Curcio; Elvis Gribaldo Aucancela Rivera; Carlo Limonti; Tiziana Andreoli; Rajandrea Sethi; Alessio Siciliano (Journal of Water Process Engineering, 2023)

Magnetic heterostructures of NiFe2O4 and TiO2: Pechini synthesis, characterization and photocatalytic performance in arsenite oxidation - Giulia Caroline de Cristo Borges; Isadora Roberta Verdi; Michel Zampieri Fidelis; Henrique Emilio Zorel Junior; Giane Gonçalves Lenzi; Éder Carlos Ferreira de Souza; Odivaldo Cambraia Alves; Rodrigo Brackmann (Journal of Water Process Engineering, 2023)

Differences in sustainability outcomes between agritourism and non-agritourism farms based on robust empirical evidence from the Tyrol/Trentino mountain region - Giulia Grillini; Giovanna Sacchi; Thomas Streifeneder; Christian Fischer (Journal of Rural Studies, 2023)

Dimensional analysis of literature formulas to estimate the characteristic flood response time in ungauged basins: A velocity-based approach - Giulia Evangelista; Ross Woods; Pierluigi Claps (Journal of Hydrology, 2023)

Varroa destructor exacerbates the negative effect of cold contributing to honey bee mortality - Davide Frizzera; Virginia Zanni; Mauro D'Agaro; Giulia Boaro; Laura Andreuzza; Simone Del Fabbro; Desiderato Annoscia; Francesco Nazzi (Journal of Insect Physiology, 2023)

Pay-as-you-throw tariff and sustainable urban waste management: An empirical analysis of relevant effects - Giulia Romano; Lucio Masserini (Journal of Environmental Management, 2023)

Hydrocarbon refrigerants boiling local heat transfer coefficients inside a Brazed Plate Heat Exchanger (BPHE) - Giovanni A. Longo; Simone Mancin; Giulia Righetti; Claudio Zilio (International Journal of Refrigeration, 2023)

Diterpenes stability of commercial blends of roasted and ground coffees packed in copolymer coupled with aluminium and eco-friendly capsules - Giulia Strocchi; Anja B. Müller; Nikolai Kuhnert; Katia Martina; Carlo Bicchi; Erica Liberto (Food Research International, 2023)

Evaluation of the behaviour of phenols and alkaloids in samples of roasted and ground coffee stored in different types of packaging: Implications for quality and shelf life - Strocchi Giulia; Bagnulo Eloisa; Ravaioli Giulia; Pellegrino Gloria; Bicchi Carlo; Liberto Erica (Food Research International, 2023)

Quantification of Salmonella transfer in cross-contamination scenarios found in chicken slaughterhouses - Giulia Giugliani Reta; Stefani Machado Lopes; Nathanyelle Soraya Martins de Aquino; Eduardo Cesar Tondo (Food Microbiology, 2023)

Canopy-forming macroalgae can adapt to marine heatwaves - Erika Fabbrizzi; Marco Munari; Simonetta Fraschetti; Carmen Arena; Antonia Chiarore; Antonio Cannavacciuolo; Alberto Colletti; Giulia Costanzo; Ana Soler-Fajardo; Matteo Nannini; Beatrice Savinelli; Chiara Silvestrini; et al. (Environmental Research, 2023)

Future-proofing the built environment: Towards a holistic approach - Giulia Ulpiani; David J. Sailor (Energy and Buildings, 2023)

Motility of Mytilus galloprovincialis hemocytes: Sensitivity to paracetamol in vitro exposure - Gayatri Udayan; Maria Elena Giordano; Patrizia Pagliara; Maria Giulia Lionetto (Aquatic Toxicology, 2023)

Flood Attenuation Potential of Italian Dams: Sensitivity on Geomorphic and Climatological Factors - Giulia Evangelista; Daniele Ganora; Paola Mazzoglio; Francesca Pianigiani; Pierluigi Claps (Water Resources Management, 2023)
In this work the attenuation potential of flood peaks of 265 large reservoirs all over Italy is analysed, considering a flood management that excludes gates opening and then configures strictly unsupervised attenuation effects. Key factors of dams and related basins are considered to develop a ranking method that can emphasize the interplay between dam geometry and the hydrological processes acting in the upstream watershed. To maintain a homogeneous approach in such a wide geographic area, the attenuation index is computed applying the numerical solution of the differential equation of lakes and only two different standardized hydrograph shapes have been used. An index design flood from the rational method is used as the incoming peak value for each dam, enhancing the use of the results of a recent analysis of all Italian rainfall extremes. Even with a very simple approach, twenty-four different design incoming floods are derived, by varying the shape of the incoming hydrograph and the parameters of the rational method. Exploring the ranking results in all the alternatives, the attenuation potential obtained for all dams demonstrates to be strongly sensitive to the assumptions on the time of concentration and to some rainfall features. On the other hand, the hydrograph shape seems to exert much less influence on the ranking outcome. Results obtained can be useful to studies of wide-area flood frequency analyses, as we highlighted the sensitivity of the rank of attenuation efficiency to hydrologic parameters widely used in the assessment of the design flood peaks in ungauged basins.

Assessing failure of transfer of passive immunity by gamma-glutamyl-transferase activity and serum refractometry in holstein-friesian calves affected by neonatal diarrhea - Giulia Sala; Valerio Bronzo; Antonio Boccardo; Alessia Libera Gazzonis; Pierangelo Moretti; Vincenzo Ferrulli; Angelo Giovanni Belloli; Laura Filippone Pavesi; Gaia Pesenti Rossi; Davide Pravettoni (Veterinary Research Communications, 2023)
Hardly published data are available to diagnose the failure of transfer of passive immunity (FTPI) in calves affected by neonatal calf diarrhea (NCD). This study evaluated the diagnostic performance and differences among optical serum total protein (STP) concentration and gamma-glutamyl-transferase (GGT) activity for assessing FTPI in diarrheic Holstein Friesian calves. 72 diarrheic and 19 healthy Holstein Friesian calves aged 1 to 10 days were enrolled. Each calf underwent a complete clinical examination and dehydration assessment. The effect of dehydration status and age on the correlation between the two methods under study (STP and GGT) and the gold standard (Immunoglobulin G [IgG] measured with RID) was investigated with Spearman’s correlation index R for ranks. Serum total protein concentration and GGT activity were analyzed by receiver operating characteristic (ROC) curve analysis to identify the optimal cut-off point to distinguish between diarrheic calves with or without FTPI, also considering the effects of dehydration and age. The results show that GGT activity was affected by the age of calves, while STP was influenced by dehydration. The cut-offs to distinguish calves with IgG < 10 g/L were < 52 g/L of STP in normohydrated calves, < 58 g/L of STP in dehydrated calves, and < 124 IU/L of GGT in calves with aged between 3 and 10 days. In nondehydrated diarrheic calves, the STP refractometer showed better diagnostic accuracy. In dehydrated calves aged between 3 and 10 days, however, its accuracy drops, and it is advisable to use GGT activity.

Turkey adenovirus 3: ORF1 gene sequence comparison between vaccine-like and field strains - Giulia Quaglia; Antonietta Di Francesco; Elena Catelli; Giulia Mescolini; Caterina Lupini (Veterinary Research Communications, 2023)
Haemorrhagic enteritis is an economically significant disease reported in the majority of the countries where turkeys are raised intensively; it is caused by Turkey adenovirus 3 (TAdV-3). The aim of this study was to analyse and compare the ORF1 gene 3′ region from turkey haemorrhagic enteritis virus (THEV) vaccine-like and field strains in order to develop a molecular diagnostic method to differentiate the strains from each other. Eighty samples were analysed by sequencing and phylogenetic analyses using a new set of polymerase chain reaction (PCR) primers targeting a genomic region spanning the partial ORF1, hyd and partial IVa2 gene sequences. A commercial live vaccine was also included in the analysis. The results showed that 56 of the 80 sequences obtained in this study showed ≥99.8% nucleotide identity with the homologous vaccine strain sequence. Three non-synonymous mutations – ntA1274G (aaI425V), ntA1420C (aaQ473H) and ntG1485A (aaR495Q) – were detected in the THEV field strains but not in the vaccine strain. Phylogenetic analysis confirmed the clustering of the field and vaccine-like strains in different phylogenetic branches. In conclusion, the method employed in this study could be a useful tool towards making a correct diagnosis. The data could contribute to the knowledge of field distribution of THEV strains and increase the limited existing information available on native isolates around the world.

Fibroblast Growth Factor Receptor 2 (FGFR2), a New Gene Involved in the Genesis of Autism Spectrum Disorder - Antonio Gennaro Nicotera; Greta Amore; Maria Concetta Saia; Mirella Vinci; Antonino Musumeci; Valeria Chiavetta; Concetta Federico; Giulia Spoto; Salvatore Saccone; Gabriella Di Rosa; Francesco Calì (NeuroMolecular Medicine, 2023)
Autism spectrum disorder (ASD) is a long-known complex neurodevelopmental disorder, and over the past decades, with the enhancement of the research genomic techniques, has been the object of intensive research activity, and many genes involved in the development and functioning of the central nervous system have been related to ASD genesis. Herein, we report a patient with severe ASD carrying a G > A de novo variant in the FGFR2 gene, determining a missense mutation. FGFR2 encodes for the ubiquitous fibroblast growth factor receptor (FGFR) type 2, a tyrosine kinase receptor implicated in several biological processes. The mutated version of this protein is known to be responsible for several variable overlapping syndromes. Even if there still is only sparse and anecdotal data, recent research highlighted a potential role of FGFR2 on neurodevelopment. Our findings provide new insights into the potential causative role of FGFR2 gene in complex neurodevelopmental disorders.

Correction: Concordance study on Y-STRs typing between SeqStudio™ genetic analyzer for HID and MiSeq™ FGx forensic genomics system - Giulia Soldati; Stefania Turrina; Mirko Treccani; Chiara Saccardo; Francesco Ausania; Domenico De Leo (Molecular Biology Reports, 2023)

Concordance study on Y-STRs typing between SeqStudio™ genetic analyzer for HID and MiSeq™ FGx forensic genomics system - Giulia Soldati; Stefania Turrina; Mirko Treccani; Chiara Saccardo; Francesco Ausania; Domenico De Leo (Molecular Biology Reports, 2023)
Background Massively Parallel Sequencing (MPS) allowed an increased number of information to be retrieved from short tandem repeat (STR) analysis, expanding them not only to the size, as already performed in Capillary Electrophoresis (CE), but also to the sequence. MPS requires constant development and validation of the analytical parameters to ensure that the genotyping results of STRs correspond to those obtained by CE. Given the increased frequency of usage of Y-STRs as supplementary markers to the autosomal STRs analysis, it is urgent to validate the concordance of the typing results between CE and MPS analyses. Methods and results DNA extracted from 125 saliva samples of unrelated males was genotyped using Yfiler™ Plus PCR Amplification Kit and ForenSeq™ DNA Signature Prep Kit, which were analyzed by SeqStudio™ Genetic Analyzer for HID and MiSeq™ FGx Forensic Genomics System, respectively. For each shared Y-STR, allele designation, number of length- and sequence-based alleles per locus, stutter percentage, and the intra-locus balance of multicopy Y-STRs were screened. Conclusions Although the number of forensic genetics laboratories that are applying the MPS technique in routine analysis is small and does not allow a global assessment of MPS limitations, this comparative study highlights the ability of MPS to produce reliable profiles despite the generation of large amounts of raw data.

Diet of loggerhead turtles in the Gulf of Manfredonia, South Adriatic Sea: evidence of winter feeding and anthropogenic impacts - Giulia Baldi; Mara Miglianti; Pasquale Salvemini; Paolo Casale (Marine Biology, 2023)
Investigating biological aspects of migratory marine animals like sea turtles is challenging. The Adriatic Sea is a key Mediterranean foraging ground for loggerhead turtles, yet certain feeding behaviors remain poorly known, including winter feeding and foraging within the neritic area of the Gulf of Manfredonia. With high fishing effort, this area experiences considerable turtle bycatch from trawlers during winter, representing an important conservation issue. Insights on how and to what extent the species interacts with anthropogenic threats such as trawlers and debris can be obtained from diet analysis. We examined feces and gut contents from 57 bycaught or stranded turtles to assess active feeding and digestion time during winter, identify and quantify prey items, evaluate feeding patterns among size classes, and ascertain the anthropogenic impact via debris and fishing discard ingestion. Our findings show that turtles feed actively during winter, primarily on benthic items, starting from a small size (32 cm Curved Carapace Length). No size effect was observed on dietary diversity or biomass percentage. We identified 37 Operational Taxonomic Units (OTUs) across 10 dietary groups, with crustaceans and mollusks being most prevalent. Osteichthyes and cephalopods, likely scavenged from trawl discard, were also common, implying intensive local trawling may attract turtles, increasing bycatch and mortality rates. The frequency of anthropogenic material ingestion was comparable to other Mediterranean regions and its presence in feces suggests non-lethal effects, if any. This study shows how information on seasonal feeding behavior can provide insights into how the relationship of the species with the environment and threats changes over time, ultimately steering conservation efforts.

GM1 structural requirements to mediate neuronal functions - Maria Fazzari; Giulia Lunghi; Erika Di Biase; Margherita Maggioni; Emma Veronica Carsana; Laura Cioccarelli; Laura Vigani; Nicoletta Loberto; Massimo Aureli; Laura Mauri; Maria Grazia Ciampa; Manuela Valsecchi; et al. (Glycoconjugate Journal, 2023)

Visceral larva Migrans in a Young Italian Patient: A Diagnostic Dilemma - Emanuela Francalanci; Tommaso Manciulli; Giulia Bandini; Pierluigi Blanc; Sara Irene Bonelli; Enrico Brunetti; Eduardo Gotuzzo; Carmen Michaela Cretu; Federico Gobbi; Alessandro Bartoloni; Lorenzo Zammarchi (Acta Parasitologica, 2023)
Background The association of fever, focal hepatic lesions and peripheral hyper-eosinophilia (FHLH) can be observed in both infectious and non-infectious conditions. Fascioliasis, capillariasis, toxocariasis, all causes of visceral larva migrans (VLM), represent most of the former, whilst lymphomas, eosinophilic leukemias and mastocytosis belong in the non-infectious conditions. Methods We prospectively followed a young patient presenting with FHLH in the Tuscany region of Italy. Results The patient was subject to serological and parasitological examination in an attempt to clarify the origin of the lesions. Serologies for both Fasciola hepatica and Toxocara spp. were positive, with the latter presenting a higher index. We opted for treatment with a prolonged course of albendazole due to the serological results and being toxocariasis more frequent in our setting. The patient was then subject to radiological follow-up. The patient responded to treatment with albendazole as shown by a decrease in eosinophils, seronegativization for Toxocara spp., clinical and radiological improvement. Toxocariasis was hence considered the most likely diagnosis. Conclusions Parasitic infections cannot be disregarded in the presence of FHLH. Differential diagnosis between these parasitic infections can be challenging due to the presence of similar clinical presentations and serological cross-reactions, and follow-up of the patient is needed to ensure optimal treatment outcomes.

High Prevalence of Hymenolepis (Rodentolepis) nana in Amateur Breeding Facilities of Chinchillas (Chinchilla lanigera) and Sugar Gliders (Petaurus breviceps) from Italy - Leonardo Brustenga; Giulia Morganti; Erika Baldoni; Gianluca Deli; Giulia Rigamonti; Livia Lucentini; Manuela Diaferia (Acta Parasitologica, 2023)

DNA metabarcoding unveils the effects of habitat fragmentation on pollinator diversity, plant‐pollinator interactions, and pollination efficiency in Maldive islands - Nicola Tommasi; Paolo Biella; Davide Maggioni; Luca Fallati; Giulia Agostinetto; Massimo Labra; Paolo Galli; Andrea Galimberti (Molecular Ecology, 2023)
Habitat fragmentation affects biodiversity, but with unclear effects on pollinators and their interactions with plants in anthropized landscapes. Islands could serve as open air laboratories, suitable to disentangle how land‐use alteration impacts pollination ecology. In Maldive islands we investigated how pollinator richness, plant‐pollinator interactions and pollination efficiency are influenced by the green area fragmentation (i.e., gardens and semi‐natural patches). Moreover, we considered the mediating role of pollinator body size and the plant trait of being invasive in shaping interactions. To do this, we surveyed pollinator insects from 11 islands representing a gradient of green area fragmentation. A DNA metabarcoding approach was adopted to identify the pollen transported by pollinators and characterize the plant‐pollinator interactions. We found that intermediate levels of green area fragmentation characterized pollinator communities and increased their species richness, while decreasing interaction network complexity. Invasive plants were more frequently found on pollinator bodies than native or exotic noninvasive ones, indicating a concerningly higher potential for pollen dispersal and reproduction of the former ones. Intriguingly, pollinator body size mediated the effect of landscape alteration on interactions, as only the largest bees expanded the foraging diet in terms of plant richness in the transported pollen at increasing fragmentation. In parallel, the pollination efficiency increased with pollinator species richness in two sentinel plants. This study shows that moderate landscape fragmentation of green areas shapes many aspects of the pollination ecosystem service, where despite interactions being less complex and mediated by pollinator body size, pollinator insect biodiversity and potential plant reproduction are supported.

RETRACTED: Future warming stimulates growth and photosynthesis in an Arctic microalga more strongly than changes in light intensity or pCO 2 - Sebastian D. Rokitta; Christian H. Grossmann; Elisa Werner; Jannika Moye; Giulia Castellani; Eva‐Maria Nöthig; Björn Rost (Limnology and Oceanography, 2023)
We assessed the responses of solitary cells of Arctic Phaeocystis pouchetii grown under a matrix of temperature (2°C vs. 6°C), light intensity (55 vs. 160 μ mol photons m −2 s −1 ) and pCO 2 (400 vs. 1000 μ atm CO 2 , i.e., 40.5 vs. 101.3 Pa). Next to acclimation parameters (growth rates, particulate and dissolved organic C and N, Chlorophyll a content), we measured physiological processes in vivo (electron transport rates and net photosynthesis) using fast‐repetition rate fluorometry and membrane‐inlet mass spectrometry. Within the applied driver ranges, elevated temperature had the most pronounced impacts, significantly increasing growth, elemental quotas and photosynthetic performance. Light stimulations manifested more prominently under 6°C, underlining temperature's role as a “master‐variable”. pCO 2 was the least effective driver, exerting mostly insignificant effects. The obtained data were used for a simplistic upscaling simulation to investigate potential changes in P. pouchetii 's bloom dynamics in the Fram Strait with increasing temperatures over the 21 st century. Although solitary cells might not be fully representative of colonial cells commonly observed in the field, our results suggest that global warming accelerates bloom dynamics, with earlier onsets of blooms and higher peak biomasses. Such a temperature‐induced acceleration in the phenology of Phaeocystis and likely other Arctic phytoplankton might cause temporal mismatches, e.g., with the development of grazers, and therefore substantially affect the biogeochemistry and ecology of the Arctic.

A multidisciplinary approach to estimating wolf population size for long‐term conservation - Francesca Marucco; Maria V. Boiani; Pierre Dupont; Cyril Milleret; Elisa Avanzinelli; Kristine Pilgrim; Michael K. Schwartz; Achaz von Hardenberg; Domenica Serena Perrone; Olivier P. Friard; Arianna Menzano; Francesco Bisi; et al. (Conservation Biology, 2023)
The wolf ( Canis lupus ) is among the most controversial of wildlife species. Abundance estimates are required to inform public debate and policy decisions, but obtaining them at biologically relevant scales is challenging. We developed a system for comprehensive population estimation across the Italian alpine region (100,000 km 2 ), involving 1513 trained operators representing 160 institutions. This extensive network allowed for coordinated genetic sample collection and landscape‐level spatial capture–recapture analyses that transcended administrative boundaries to produce the first estimates of key parameters for wolf population status assessment. Wolf abundance was estimated at 952 individuals (95% credible interval 816–1120) and 135 reproductive units (i.e., packs) (95% credible interval 112–165). We also estimated that mature individuals accounted for 33–45% of the entire population. The monitoring effort was spatially estimated thereby overcoming an important limitation of citizen science data. This is an important approach for promoting wolf–human coexistence based on wolf abundance monitoring and an endorsement of large‐scale harmonized conservation practices.

Low circulating levels of miR-17 and miR-126-3p are associated with increased mortality risk in geriatric hospitalized patients affected by cardiovascular multimorbidity - Francesca Marchegiani; Rina Recchioni; Mirko Di Rosa; Francesco Piacenza; Fiorella Marcheselli; Anna Rita Bonfigli; Roberta Galeazzi; Giulia Matacchione; Maurizio Cardelli; Antonio Domenico Procopio; Andrea Corsonello; Antonio Cherubini; et al. (GeroScience, 2023)
MultiMorbidity (MM), defined as the co-occurrence of two or more chronic conditions, is associated with poorer health outcomes, such as recurrent hospital readmission and mortality. As a group of conditions, cardiovascular disease (CVD) exemplifies several challenges of MM, and the identification of prognostic minimally invasive biomarkers to stratify mortality risk in patients affected by cardiovascular MM is a huge challenge. Circulating miRNAs associated to inflammaging and endothelial dysfunction, such as miR-17, miR-21-5p, and miR-126-3p, are expected to have prognostic relevance. We analyzed a composite profile of circulating biomarkers, including miR-17, miR-21-5p, and miR-126-3p, and routine laboratory biomarkers in a sample of 246 hospitalized geriatric patients selected for cardiovascular MM from the Report-AGE INRCA database and BioGER INRCA biobank, to evaluate the association with all-cause mortality during 31 days and 12 and 24 months follow-up. Circulating levels of miR-17, miR-126-3p, and some blood parameters, including neutrophil to lymphocyte ratio (NLR) and eGFR, were significantly associated with mortality in these patients. Overall, our results suggest that in a cohort of geriatric hospitalized patients affected by cardiovascular MM, lower circulating miR-17 and miR-126-3p levels could contribute to identify patients at higher risk of short- and medium-term mortality.

Effect of the use of biocontrol agents and resistance inducers against race 1 of Fusarium oxysporum f. sp. lactucae on lettuce in a simulated climate change scenario - Giovanna Gilardi; Giulia Tabone; Maria Lodovica Gullino; Angelo Garibaldi (Journal of Plant Pathology, 2023)

Rapid measurement of ageing by automated monitoring of movement of C. elegans populations - Giulia Zavagno; Adelaide Raimundo; Andy Kirby; Christopher Saunter; David Weinkove (GeroScience, 2023)
Finding new interventions that slow ageing and maintain human health is a huge challenge of our time. The nematode Caenorhabditis elegans offers a rapid in vivo method to determine whether a compound extends its 2 to 3-week lifespan. Measuring lifespan is the standard method to monitor ageing, but a compound that extends lifespan will not necessarily maintain health. Here, we describe the automated monitoring of C. elegans movement from early to mid-adulthood as a faster healthspan-based method to measure ageing. Using the WormGazer™ technology, multiple Petri dishes each containing several C. elegans worms are imaged simultaneously and non-invasively by an array of cameras that can be scaled easily. This approach demonstrates that most functional decline in C. elegans occurs during the first week of adulthood. We find 7 days of imaging is sufficient to measure the dose-dependent efficacy of sulfamethoxazole to slow ageing, compared to 40 days required for a parallel lifespan experiment. Understanding any negative consequences of interventions that slow ageing is important. We show that the long-lived mutant age-1(hx546) stays active for longer than the wild type but it moves slower in early adulthood. Thus, continuous analysis of movement can rapidly identify interventions that slow ageing while simultaneously revealing any negative effects on health.

Limitations in the use of Sentinel-1 data for morphological change detection in rivers - Giulia Marchetti; Andrea Manconi; Francesco Comiti (International Journal of Remote Sensing, 2023)

Epidemiology, time course, and risk factors for hospital-acquired bloodstream infections in a cohort of 14,884 patients before and during the COVID-19 pandemic - Eleonora Taddei; Pia Clara Pafundi; Carlotta Masciocchi; Barbara Fiori; Francesco Vladimiro Segala; Laura Antenucci; Silvia Guerriero; Roberta Pastorino; Nicolò Scarsi; Andrea Damiani; Maurizio Sanguinetti; Gennaro De Pascale; et al. (Infectious Diseases, 2023)

Ecosystems of Italy. Updated mapping and typology for the implementation of national and international biodiversity-related policies - Giulia Capotorti; Eva Del Vico; Riccardo Copiz; Laura Facioni; Laura Zavattero; Sandro Bonacquisti; Massimo Paolanti; Carlo Blasi (Plant Biosystems, 2023)

Ecotoxicological assessment of water phase exfoliated two-dimensional Group-VI transition metal dichalcogenides using zebrafish embryo model - Carmine Merola; Annalisa Scroccarello; Flavio Della Pelle; Giovanni Ferraro; Giulia Caioni; Monia Perugini; Michele Amorena; Dario Compagnone (Chemosphere, 2023)

Products, reactive species and mechanisms of PFOA degradation in a self-pulsing discharge (SPD) plasma reactor - Omar Biondo; Giulia Tomei; Mubbshir Saleem; Goran B. Sretenović; Mirko Magarotto; Ester Marotta; Cristina Paradisi (Chemosphere, 2023)

Complementary feeding approach and maternal responsiveness in 8- and 12-month-old Italian infants: A longitudinal study - Alice Di Prete; Denise Del Grosso; Valentina Focaroli; Melania Paoletti; Giulia Pecora; Eric A. Hodges; Amy T. Galloway; Claire Farrow; Flavia Chiarotti; Barbara Caravale; Corinna Gasparini; Serena Gastaldi; et al. (Appetite, 2023)

Implementing urban resilience in urban planning: A comprehensive framework for urban resilience evaluation - Giulia Datola (Sustainable Cities and Society, 2023)

On the performance-based seismic design of yielding retaining structures - Riccardo Conti; Giulia M.B. Viggiani (Soil Dynamics and Earthquake Engineering, 2023)

Teratogenic effects of environmental concentration of plastic particles on freshwater organisms - Giulia Cesarini; Silvia Secco; Davide Taurozzi; Iole Venditti; Chiara Battocchio; Stefania Marcheggiani; Laura Mancini; Ilaria Fratoddi; Massimiliano Scalici; Camilla Puccinelli (Science of The Total Environment, 2023)

LCA based circularity indices of systems at different scales: a holistic approach - Simone Bastianoni; Giulia Goffetti; Elena Neri; Nicoletta Patrizi; Anna Ruini; Fabio Sporchia; Federico M. Pulselli (Science of The Total Environment, 2023)

Using PlanetScope images to investigate the evolution of small glaciers in the Alps - Giulia Tarca; Martin Hoelzle; Mauro Guglielmin (Remote Sensing Applications: Society and Environment, 2023)

Cultivable mycoflora on bleached, decaying and healthy Posidonia oceanica leaves in a warm-edge Mediterranean location - Patrizia Stipcich; Virgilio Balmas; Carlos E. Jimenez; Safa Oufensou; Giulia Ceccherelli (Marine Environmental Research, 2023)

Characterizing CONUS-wide spatio-temporal changes in daily precipitation, flow, and variability of extremes - Shah Afzal Saki; Giulia Sofia; Emmanouil N. Anagnostou (Journal of Hydrology, 2023)

Assessing the compound flood risk in coastal areas: Framework formulation and demonstration - Mahjabeen Fatema Mitu; Giulia Sofia; Xinyi Shen; Emmanouil N. Anagnostou (Journal of Hydrology, 2023)

Detection of Lotmaria passim in honeybees from Emilia Romagna (Italy) based on a culture method - Cecilia Rudelli; Gloria Isani; Giulia Andreani; Perla Tedesco; Roberta Galuppi (Journal of Invertebrate Pathology, 2023)

Effect of quality of separately collected glass, paper plus cardboard and lightweight packaging waste on environmental, energetic and economic sustainability of the material recovery facility operations - Adolfo Le Pera; Miriam Sellaro; Giulia Grande; Egidio Bencivenni; Massimo Migliori (Journal of Cleaner Production, 2023)

Traditional vs. novel approaches to coastal risk management: A review and insights from Italy - Giulia Motta Zanin; Angela Barbanente; Claudia Romagnoli; Alessandro Parisi; Renata Archetti (Journal of Environmental Management, 2023)

The influence of oyster reefs and surrounding sediments on nitrogen removal – An in-situ study along the East coast of Australia - Giulia Filippini; Ana B. Bugnot; Angus Ferguson; Paul E. Gribben; Julia Palmer; Katherine Erickson; Katherine A. Dafforn (Environmental Research, 2023)

Hair as an alternative matrix to assess exposure of premature neonates to phthalate and alternative plasticizers in the neonatal intensive care unit - Paulien Cleys; Lucas Panneel; Jasper Bombeke; Catalina Dumitrascu; Govindan Malarvannan; Giulia Poma; Antonius Mulder; Philippe G. Jorens; Adrian Covaci (Environmental Research, 2023)

Microplastics evidence in yolk and liver of loggerhead sea turtles (Caretta caretta), a pilot study. - Giulia Chemello; Erica Trotta; Valentina Notarstefano; Luana Papetti; Ludovica Di Renzo; Marco Matiddi; Cecilia Silvestri; Oliana Carnevali; Giorgia Gioacchini (Environmental Pollution, 2023)

Air pollution, social engagement, and depression in older adults: Results from a Swedish population-based cohort study - Jing Wu; Giulia Grande; Federico Triolo; Andrei Pyko; Linnea Sjöberg; Petter Ljungman; Kristina Eneroth; Tom Bellander; Debora Rizzuto (Environmental Pollution, 2023)

Experimental assessment of the heat mitigation potential of an urban cooling shelter: Combining water misting with solar shading, wind shield, and smart control - Giulia Ulpiani; Michele Zinzi (Energy and Buildings, 2023)

Benchmarking the energy performance of European commercial buildings with a bayesian modeling framework - Horace Guy; Simon Vittoz; Giulia Caputo; Thimothée Thiery (Energy and Buildings, 2023)

Missing steps in the assessment of the local economic impact of nuclear waste: The case of Italy - Alessandro Marra; Giulia Di Giorgio (Environmental Impact Assessment Review, 2023)

Responses of soil microarthropods to soil metal fractions under different mediterranean vegetation covers - Lucia Santorufo; Valeria Memoli; Giorgia Santini; Gabriella Di Natale; Marco Trifuoggi; Rossella Barile; Giulia Maisto (CATENA, 2023)

Green solvents to enhance hydrochar quality and clarify effects of secondary char - Giulia Ischia; Jillian L. Goldfarb; Antonio Miotello; Luca Fiori (Bioresource Technology, 2023)

Urban microclimate simulations based on GIS data to mitigate thermal hot-spots: Tree design scenarios in an industrial area of Florence - Giulia Guerri; Alfonso Crisci; Marco Morabito (Building and Environment, 2023)

Understanding the Ultra-Rare Disease Autosomal Dominant Leukodystrophy: an Updated Review on Morpho-Functional Alterations Found in Experimental Models - Irene Neri; Giulia Ramazzotti; Sara Mongiorgi; Isabella Rusciano; Marianna Bugiani; Luciano Conti; Margot Cousin; Elisa Giorgio; Quasar S. Padiath; Giovanna Vaula; Pietro Cortelli; Lucia Manzoli; et al. (Molecular Neurobiology, 2023)
Autosomal dominant leukodystrophy (ADLD) is an ultra-rare, slowly progressive, and fatal neurodegenerative disorder associated with the loss of white matter in the central nervous system (CNS). Several years after its first clinical description, ADLD was found to be caused by coding and non-coding variants in the LMNB1 gene that cause its overexpression in at least the brain of patients. LMNB1 encodes for Lamin B1, a protein of the nuclear lamina. Lamin B1 regulates many cellular processes such as DNA replication, chromatin organization, and senescence. However, its functions have not been fully characterized yet. Nevertheless, Lamin B1 together with the other lamins that constitute the nuclear lamina has firstly the key role of maintaining the nuclear structure. Being the nucleus a dynamic system subject to both biochemical and mechanical regulation, it is conceivable that changes to its structural homeostasis might translate into functional alterations. Under this light, this review aims at describing the pieces of evidence that to date have been obtained regarding the effects of LMNB1 overexpression on cellular morphology and functionality. Moreover, we suggest that further investigation on ADLD morpho-functional consequences is essential to better understand this complex disease and, possibly, other neurological disorders affecting CNS myelination. Graphical Abstract

Stenotrophomonas maltophilia in people with Cystic Fibrosis: a systematic review of prevalence, risk factors and management - Vito Terlizzi; Marta Tomaselli; Giulia Giacomini; Irene Dalpiaz; Elena Chiappini (European Journal of Clinical Microbiology & Infectious Diseases, 2023)
To summarize the current knowledge of the clinical impact of Stenotrophomonas maltophilia ( SM ) in cystic fibrosis (CF) patients. A systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guideline recommendations, was performed through searches in PubMed and EMBASE databases, and CF National and International Registries websites from 2000 to 2022. Overall, 184 articles were initially retrieved, out of which 15 were selected and included in the review. Data form 6 Registries and 9 pertinent articles from the references of the studies selected were also considered, resulting in 30 studies in total. The prevalence of SM in patients with CF is increasing in Europe while it is declining in North America. The role of chronic colonization of SM on lung function and clinical status in CF patients is still under debate. The most recent studies suggested a pathogenic role of SM chronic infections in CF patients with an acceleration in lung function decline, an increase in hospitalization rates and an association with co-infection. Reflecting the uncertainty about the role of SM in CF, little is available about antibiotic therapeutic strategies for both acute exacerbations and chronic infections. Antimicrobial therapy should be performed in the acute exacerbations, while it may be reasonable to attempt eradication when the first colonization is identified. Nevertheless, it is not established which antibiotic regimen should be preferred, and overtreatment could contribute to the selection of antimicrobial-resistant strains. Further studies are warranted in this regard.

Process understanding and monitoring: A glimpse into data strategies for miniaturized NIR spectrometers - Giulia Gorla; Alberto Ferrer; Barbara Giussani (Analytica Chimica Acta, 2023)

The role of aftercare in plant translocation - Anna Corli; Giulia Albani Rocchetti; Simone Orsenigo; Jennifer Possley; Thomas Abeli (Biodiversity and Conservation, 2023)
Plant translocation can increase the chances of long-term survival of threatened plant species; nevertheless, can be costly and challenging, with unknowns in the pre- and post-release phases, limiting success. Methodological advances have been made in the pre-release phase but long-term monitoring and post-release site management (i.e., “aftercare”) are not always applied and almost neglected in the literature despite being frequently effective for identifying and mitigating unexpected threats (e.g., interspecific competition, herbivory) to outplant survival. Aiming to fill this gap, we reviewed published and gray literature on 296 translocations to shed light on the importance of aftercare on translocation outcome. We identified the most common aftercare techniques, then we performed a meta-analysis on a subset of studies that were specifically designed to test the effect of aftercare against a control (i.e., no aftercare). The most common aftercare techniques were competition reduction, water irrigation and plant protection. Aftercare significantly increased the percentage of survival of plants when herbivory reduction and other understorey species were enhanced. Aftercare reported also a positive trend toward improved qualitative outcome when plants were protected or competition was mitigated. Nevertheless, more evidence is needed on the importance and effectiveness of aftercare techniques. Long-term monitoring and post-release site management should be the post-translocation standard in plant translocations when ethical and possible, with plant protection, competition limitation and water irrigation being applied when needed to reduce transplant mortality. To provide statistically supported data on the effect of aftercare on translocation outcome, aftercare should be tested against a control when feasible.

High promiscuity among females of the invasive pest species Drosophila suzukii - Simone Puppato; Giulia Fiorenza; Davide Carraretto; Ludvik Marcus Gomulski; Giuliano Gasperi; Carlos Caceres; Alberto Grassi; Maria Vittoria Mancini; Antonio De Cristofaro; Claudio Ioriatti; Robin Guilhot; Anna Rodolfa Malacrida (Molecular Ecology, 2023)
Drosophila suzukii (Matsumura, 1931), the spotted‐wing drosophila, is a highly invasive fruit fly that spread from Southern Asia across most regions of Asia and, in the last 15 years, has invaded Europe and the Americas. It is an economically important pest of small fruits such as berries and stone fruits. Drosophila suzukii speciated by adapting to cooler, mountainous, and forest environments. In temperate regions, it evolved seasonal polyphenism traits which enhanced its survival during stressful winter population bottlenecks. Consequently, in these temperate regions, the populations undergo seasonal reproductive dynamics. Despite its economic importance, no data are available on the behavioural reproductive strategies of this fly. The presence of polyandry, for example, has not been determined despite the important role it might play in the reproductive dynamics of populations. We explored the presence of polyandry in an established population in Trentino, a region in northern Italy. In this area, D. suzukii overcomes the winter bottleneck and undergoes a seasonal reproductive fluctuation. We observed a high remating frequency in females during the late spring demographic explosion that led to the abundant summer population. The presence of a high degree of polyandry and shared paternity associated with the post‐winter population increase raises the question of the possible evolutionary adaptive role of this reproductive behaviour in D. suzukii .

Marine heatwaves on the rise: One of the strongest ever observed mass mortality event in temperate gorgonians - Tristan Estaque; Justine Richaume; Olivier Bianchimani; Quentin Schull; Bastien Mérigot; Nathaniel Bensoussan; Patrick Bonhomme; Pauline Vouriot; Stéphane Sartoretto; Tiffany Monfort; Solène Basthard‐Bogain; Margaux Fargetton; et al. (Global Change Biology, 2023)

The Frequency of Intermediate Alleles in Patients with Cerebellar Phenotypes - Elena Capacci; Silvia Bagnoli; Giulia Giacomucci; Costanza Maria Rapillo; Alessandra Govoni; Valentina Bessi; Cristina Polito; Irene Giotti; Alice Brogi; Elisabetta Pelo; Sandro Sorbi; Benedetta Nacmias; et al. (The Cerebellum, 2023)
Cerebellar syndromes are clinically and etiologically heterogeneous and can be classified as hereditary, neurodegenerative non-hereditary, or acquired. Few data are available on the frequency of each form in the clinical setting. Growing interest is emerging regarding the genetic forms caused by triplet repeat expansions. Alleles with repeat expansion lower than the pathological threshold, termed intermediate alleles (IAs), have been found to be associated with disease manifestation. In order to assess the relevance of IAs as a cause of cerebellar syndromes, we enrolled 66 unrelated Italian ataxic patients and described the distribution of the different etiology of their syndromes and the frequency of IAs. Each patient underwent complete clinical, hematological, and neurophysiological assessments, neuroimaging evaluations, and genetic tests for autosomal dominant cerebellar ataxia (SCA) and fragile X-associated tremor/ataxia syndrome (FXTAS). We identified the following diagnostic categories: 28% sporadic adult-onset ataxia, 18% cerebellar variant of multiple system atrophy, 9% acquired forms, 9% genetic forms with full-range expansion, and 12% cases with intermediate-range expansion. The IAs were six in the FMR1 gene, two in the gene responsible for SCA8, and one in the ATXN2 gene. The clinical phenotype of patients carrying the IAs resembles, in most of the cases, the one associated with full-range expansion. Our study provides an exhaustive description of the causes of cerebellar ataxia, estimating for the first time the frequency of IAs in SCAs- and FXTAS-associated genes. The high percentage of cases with IAs supports further screening among patients with cerebellar syndromes.

Characterizing Håkon Mosby Mud Volcano (Barents Sea) cold seep systems by combining ROV-based acoustic data and underwater photogrammetry - Luca Fallati; Giuliana Panieri; Claudio Argentino; Andrea Giulia Varzi; Stefan Bünz; Alessandra Savini (Frontiers in Marine Science, 2023)
Cold-seeps have a unique geo-ecological significance in the deep-sea environment. They impact the variability of present-day submarine sedimentary environments, affecting the evolution of the landscape over time and creating a variety of submarine landforms, one of which is Mud Volcanoes (MVs). MVs form due to the extrusion of mud, fluids, and gas, mainly methane, from deeper sedimentary layers. These natural gas seepage systems could significantly affect climate change and the global carbon cycle. We present a comprehensive method that combines ROV-based multibeam mapping and underwater photogrammetry to enhance the understanding of the physical relationships between geomorphic units characterizing the Håkon Mosby Mud Volcano (HMMV) and the distribution of associated habitats. HMMV is indeed characterized by high thermal and geochemical gradients from its center to the margins resulting in a clear zonation of chemosynthetic communities. Our approach integrates multi-resolutions and multi-sources data acquired using a work-class ROV. The ROV-based microbathymetry data helped to identify the different types of fine-scale submarine landforms in the central part of HMMV. This revealed three distinct geomorphic units, with the central hummocky region being the most complex. To further study this area, ROV images were analyzed using a defined Structure from Motion workflow producing millimetric resolution 2D and 3D models. Object-Based Image Analysis (OBIA), applied on orthomosaics, allowed us to obtain a fine classification of main benthic communities covering a total area of 940m 2 , including the active seepage area of the hummocky rim. Four major substrate types were identified in these regions: uncovered mud, bacterial mats high-density, bacterial mats low-density, sediments and tubeworms . Their relationship with terrain morphology and seepage activity were investigated at different spatial scales, contributing to a deeper understanding the ecological functioning of cold seep ecosystems in MVs. The applied workflow is proposed as an innovative processing technique for future studies on cold-seep systems. Geomorphic and ecological processes in extreme environments are inherently linked and marked by spatial patterns typifying associated habitats and sedimentary environments. This is poorly investigated in previous studies, leaving a substantial gap in the geomorphological drivers responsible for habitat distribution and extent in cold seep systems.

Neuroanatomical findings in isolated REM sleep behavior disorder and early Parkinson’s disease: a Voxel-based morphometry study - Giulia Donzuso; Calogero E. Cicero; Loretta Giuliano; Raffaele Squillaci; Antonina Luca; Stefano Palmucci; Antonello Basile; Giuseppe Lanza; Raffaele Ferri; Mario Zappia; Alessandra Nicoletti (Brain Imaging and Behavior, 2023)
Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is a parasomnia characterized by loss of physiological atonia of skeletal muscles with abnormal behaviors arising during REM sleep. RBD is often the early manifestation of neurodegenerative diseases, particularly alpha-synucleinopathies, such as Parkinson’s disease (PD). Both structural and functional neuroimaging studies suggest that iRBD might share, or even precede, some of the features commonly found in PD, although without a definitive conclusion. Aim of the study is to evaluate the presence of structural abnormalities involving cortical and subcortical areas in PD patients with RBD and iRBD. Patients with video-polysomnographic (VPSG)-confirmed iRBD, and patients with a diagnosis of PD were recruited. In all PD patients, the presence of probable RBD was assessed during the follow-up visits (PD/pRBD). A group of healthy controls (HC) subjects was also recruited. Each subject underwent a structural brain MRI using a 3-D T1-weighted spoiled gradient echo sequence. Twenty-three patients with iRBD, 24 PD/pRBD, and 26 HC were enrolled. Voxel-based morphometry-AnCOVA analysis revealed clusters of grey matter changes in iRBD and PD/pRBD compared to HC in several regions, involving mainly the frontal and temporal regions. The involvement of cortical brain structures associated to the control of sleep cycle and REM stage both in PD/pRBD and iRBD might suggest the presence of a common structural platform linking iRBD and PD, although this pattern may not underlie exclusively RBD-related features. Further longitudinal studies are needed to clarify the patterns of changes occurring at different time points of RBD-related neurodegeneration.

One year study on the reproductive biology, ovary characterization and age of the European sardine (Sardina pilchardus) in the middle-west Adriatic Sea - Giulia Chemello; Greta Lucia Cerrone; Valentina Tavolazzi; Fortunata Donato; Francesco Tiralongo; Giorgia Gioacchini (Frontiers in Marine Science, 2023)
The ecological and economic relevance of the European sardine ( Sardina pilchardus ) in the Adriatic area is well established. High exploitation rates and instability of environmental parameters could potentially impair the reproductive physiology of this species, compromising the stock’s stability. To guarantee efficient stock management, there is a need to fill the lack of updated information regarding the structure, sex ratio and reproductive season of the sardine population in the Adriatic Sea. The present study provides new data on the distribution of females’ maturation phases, sex ratio, age frequency and seasonality of the reproductive period in the middle-western Adriatic Sea. Sardine specimens were collected monthly, from April 2021 to March 2022 in the Adriatic waters off the coast of Ancona. Size, weight and sex were determined for a sub-sample of almost 144 specimens during each sampling period. Through otolith analysis and ovary characterization, population age and females’ maturation phase were estimated respectively. The results obtained highlighted a general reduction in size (15.5cm the highest size class) and age (maximum age 2+, greater than 2 years old but less than 3 years) of the population that was characterized by the predominance of males. Also, an interesting scarcity of small female specimens (< 13 cm length) was observed. The reproductive period seemed to occur between October and June as suggested by ovarian characterization, GSI (0.50, 0.30 and 0.62 respectively) and Fulton’s condition factor (0.73, 0.74 and 0.74 respectively) analysis that showed the lowest values in July, August and September corresponding to the rest period.

Severe Neurodevelopmental Disorder in Autosomal Recessive Spinocerebellar Ataxia 13 (SCAR13) Caused by Two Novel Frameshift Variants in GRM1 - Carlo Alberto Cesaroni; Giulia Pisanò; Gabriele Trimarchi; Stefano Giuseppe Caraffi; Giulia Scandolo; Martina Gnazzo; Daniele Frattini; Carlotta Spagnoli; Susanna Rizzi; Claudia Dittadi; Giulia Sigona; Livia Garavelli; et al. (The Cerebellum, 2023)

Organophosphate diesters (DAPs) and hydroxylated organophosphate flame retardants (HO-OPFRs) as biomarkers of OPFR contamination in a typical freshwater food chain - Yin-E Liu; Xiao-Jun Luo; Hong-Chang Ding; Lin Qi; Bin Tang; Bi-Xian Mai; Giulia Poma; Adrian Covaci (Chemosphere, 2023)