Concentrations and co-occurrence of 101 emerging and legacy organic pollutants in the ultrafine, fine and coarse fractions of airborne particulates associated with treatment of waste from electrical and electronic equipment - Donatella Pomata; Patrizia Di Filippo; Carmela Riccardi; Francesca Buiarelli; Federico Marini; Leonardo Romani; Franco Lucarelli; Giulia Pazzi; Roberta Galarini; Giulia Simonetti (Chemosphere, 2023)

Effect of exclusion net timing of deployment and color on Halyomorpha halys (Hemiptera: Pentatomidae) infestation in pear and apple orchards - Diego Fornasiero; Davide Scaccini; Veronica Lombardo; Giulia Galli; Alberto Pozzebon (Crop Protection, 2023)

Primary settling changes the microbial community of influent wastewater to wastewater treatment plants - Marie Riisgaard-Jensen; Giulia Dottorini; Marta Nierychlo; Per Halkjær Nielsen (Water Research, 2023)

Urban environment and green spaces as factors influencing sedentary behaviour in school-aged children - Giulia Squillacioti; Samuele De Petris; Valeria Bellisario; Enrico Corrado Borgogno Mondino; Roberto Bono (Urban Forestry & Urban Greening, 2023)

Human exposure to persistent and mobile chemicals: A review of sources, internal levels and health implications - Da-Hye Kim; Yu Ait Bamai; Lidia Belova; Jos Bessems; Giulia Poma; Adrian Covaci (Science of The Total Environment, 2023)

Associations between serum gamma-globulin concentration, enzyme activities, growth and survival in preweaning Alpine goat kids - Mariana Roccaro; Marilena Bolcato; Maria Giulia Ferrari; Francesco Dondi; Arcangelo Gentile; Angelo Peli (Small Ruminant Research, 2023)

Effects of ocean warming and pollution on Sargassum forests - Letícia M. Costa Peres; Lidiane P. Gouvêa; Juliana Hayden; Giulia Burle; Eduardo Bastos; Alessandra Carneiro; Paulo A. Horta (Marine Environmental Research, 2023)

Linseed supplementation in the diet of fattening pigs: Effect on the fatty acid profile of different pork cuts - Monica Tognocchi; Giuseppe Conte; Alberto Mantino; Giulia Foggi; Laura Casarosa; Sara Tinagli; Luca Turini; Federica Scicutella; Marcello Mele; Andrea Serra (Meat Science, 2023)

A combined treatment of aerobic activated sludge and powdered activated carbon: Pilot-scale study of per/polyfluoroalkyls (PFASs), organic matters, chromium, and color removal from tannery wastewaters - Marco Gottardo; Giulia Adele Tuci; Aditi Chitharanjan Parmar; Paolo Pavan; Francesco Valentino (Journal of Water Process Engineering, 2023)

Circular economy and waste management to empower a climate-neutral urban future - Margot Möslinger; Giulia Ulpiani; Nadja Vetters (Journal of Cleaner Production, 2023)

Experimental assessment of low temperature phase change materials (PCM) for refrigerating and air conditioning applications - Dario Guarda; Giulia Righetti; Giovanni A. Longo; Claudio Zilio; Simone Mancin (International Journal of Refrigeration, 2023)

Estimating the concentration of total suspended solids in inland and coastal waters from Sentinel-2 MSI: A semi-analytical approach - Dalin Jiang; Bunkei Matsushita; Nima Pahlevan; Daniela Gurlin; Cédric G. Fichot; Joshua Harringmeyer; Giulia Sent; Ana C. Brito; Vanda Brotas; Mortimer Werther; Veloisa Mascarenhas; Matthew Blake; et al. (ISPRS Journal of Photogrammetry and Remote Sensing, 2023)

The impact of milk storage temperatures on cheese quality and microbial communities at dairy processing plant scale - Lucia Giagnoni; Saptarathi Deb; Alessandra Tondello; Giulia Zardinoni; Michele De Noni; Cinzia Franchin; Alice Vanzin; Giorgio Arrigoni; Antonio Masi; Piergiorgio Stevanato; Alessio Cecchinato; Andrea Squartini; et al. (Food Research International, 2023)

Nudging Italian university students towards healthy and sustainable food choices: An online experiment - Rungsaran Wongprawmas; Giulia Andreani; Cinzia Franchini; Beatrice Biasini; Alice Rosi; Irina Dolgopolova; Jutta Roosen; Davide Menozzi; Miguel I. Gómez; Francesca Scazzina; Cristina Mora; Giovanni Sogari (Food Quality and Preference, 2023)

The stress granule component TIAR during the non-embryonic development of the colonial ascidian Botryllus schlosseri - Laura Drago; Giulia Perin; Gianfranco Santovito; Loriano Ballarin (Fish & Shellfish Immunology, 2023)

Expansion of the cytochrome C oxidase subunit I database and description of four new lobose testate amoebae species (Amoebozoa; Arcellinida) - Giulia M. Ribeiro; Fernando Useros; Kenneth Dumack; Rubén González-Miguéns; Ferry Siemensma; Alfredo L. Porfírio-Sousa; Carmen Soler-Zamora; João Pedro Barbosa Alcino; Daniel J.G. Lahr; Enrique Lara (European Journal of Protistology, 2023)

Exposure to secondhand and thirdhand smoke in private vehicles: Measurements in air and dust samples - Xavier Continente; Elisabet Henderson; Laura López-González; Esteve Fernández; Olena Tigova; Sean Semple; Rachel O'Donnell; Ana Navas-Acién; Núria Cortés-Francisco; Noelia Ramírez; Ruaraidh Dobson; Maria José López; et al. (Environmental Research, 2023)

Bisphenols and perfluoroalkyls alter human stem cells integrity: A possible link with infertility - Giulia Gaggi; Andrea Di Credico; Federica Barbagallo; Barbara Ghinassi; Angela Di Baldassarre (Environmental Research, 2023)

Nitrogen fertilization and arbuscular mycorrhizal fungi do not mitigate the adverse effects of soil contamination with polypropylene microfibers on maize growth - Dario Giambalvo; Gaetano Amato; Rosolino Ingraffia; Antonella Lo Porto; Giulia Mirabile; Paolo Ruisi; Livio Torta; Alfonso S. Frenda (Environmental Pollution, 2023)

Multi-year total ozone column variability at three Norwegian sites and the influence of Northern Hemisphere Climatic indices - Giulia Boccacci; Chiara Bertolin; Stefano Cavazzani; Anna Maria Siani (Atmospheric Environment, 2023)

Reprogramming Human Female Adipose Mesenchymal Stem Cells into Primordial Germ Cell-Like Cells - Giulia Salvatore; Susanna Dolci; Antonella Camaioni; Francesca Gioia Klinger; Massimo De Felici (Stem Cell Reviews and Reports, 2023)
In the last two decades, considerable progress has been made in the derivation of mammalian germ cells from pluripotent stem cells such as Embryonic Stem Cells (ESCs) and induced Pluripotent Stem Cells (iPSCs). The pluripotent stem cells are generally first induced into pre-gastrulating endoderm/mesoderm-like status and then specified into putative primordial germ cells (PGCs) termed PGC-like cells (PGCLCs) which possess the potential to generate oocytes and sperms. Adipose-derived mesenchymal stromal cells (ASCs) are multipotent cells, having the capacity to differentiate into cell types such as adipocytes, osteocytes and chondrocytes. Since no information is available about the capability of female human ASCs (hASCs) to generate PGCLCs, we compared protocols to produce such cells from hASCs themselves or from hASC-derived iPSCs. The results showed that, providing pre-induction into a peri-gastrulating endoderm/mesoderm-like status, hASCs can generate PGCLCs. This process, however, shows a lower efficiency than when hASC-derived iPSCs are used as starting cells. Although hASCs possess multipotency and express mesodermal genes, direct induction into PGCLCs resulted less efficient.

Supraspinal neuroinflammation and anxio-depressive-like behaviors in young- and older- adult mice with osteoarthritis pain: the effect of morphine - Giada Amodeo; Silvia Franchi; Simona D’Agnelli; Giulia Galimberti; Marco Baciarello; Elena Giovanna Bignami; Paola Sacerdote (Psychopharmacology, 2023)
Rationale Asteoarthritis (OA) is a leading cause of chronic pain in the elderly population and is often associated with emotional comorbidities such as anxiety and depression. Despite age is a risk factor for both OA and mood disorders, preclinical studies are mainly conducted in young adult animals. Objectives Here, using young adult (11-week-old) and older adult (20-month-old) mice, we evaluate in a monosodium-iodoacetate-(MIA)-induced OA model the development of anxio-depressive-like behaviors and whether brain neuroinflammation may underlie the observed changes. We also test whether an effective pain treatment may prevent behavioral and biochemical alterations. Methods Mechanical allodynia was monitored throughout the experimental protocol, while at the end of protocol (14 days), anxio-depressive-like behaviors and cognitive dysfunction were assessed. Neuroinflammatory condition was evaluated in prefrontal cortex, hippocampus and hypothalamus. Serum IFNγ levels were also measured. Moreover, we test the efficacy of a 1-week treatment with morphine (2.5 mg/kg) on pain, mood alterations and neuroinflammation. Results We observed that young adult and older adult controls (CTRs) mice had comparable allodynic thresholds and developed similar allodynia after MIA injection. Older adult CTRs were characterized by altered behavior in the tests used to assess the presence of depression and cognitive impairment and by elevated neuroinflammatory markers in brain areas compared to younger ones. The presence of pain induced depressive-like behavior and neuroinflammation in adult young mice, anxiety-like behavior in both age groups and worsened neuroinflammation in older adult mice. Morphine treatment counteracted pain, anxio-depressive behaviors and neuroinflammatory activation in both young adult and older adult mice. Conclusions Here, we demonstrated that the presence of chronic pain in young adult mice induces mood alterations and supraspinal biochemical changes and aggravates the alterations already evident in older adult animals. A treatment with morphine, counteracting the pain, prevents the development of anxio-depressive disorders and reduces neuroinflammation.

Monitoring temporal changes in coastal mangroves to understand the impacts of climate change: Red Sea, Egypt - Abdelraouf A Moustafa; Amira Abdelfath; Mohamed O. Arnous; Ayman M Afifi; Giulia Guerriero; David R. Green (Journal of Coastal Conservation, 2023)
This paper focuses on the current state of mangroves in Egypt, analyses how climate change is affecting mangrove forests and suggests a conservation strategy to safeguard this valuable maritime resource. Mangroves in Egypt are primarily found in regions around the Red Sea, making them popular for ecotourism across the globe. A crucial breeding and feeding ground for many commercial fishery species, mangroves are a maritime habitat that is both economically and environmentally significant and a variety of living things call them home. Mangroves are one of the most threatened tropical and subtropical ecoregions in the world. These threats come from both natural and human sources, including oil spills, human waste runoff, herbicide use, and coastal development, all of which have the potential to harm the environment. Mangrove habitats are immediately impacted by salinity changes and rising sea levels brought on by climate change. This is unfortunate as mangroves are one of the most important global carbon sinks, and their loss due to climate change may accelerate sea level rise and ocean acidification, which will cause the extinction of numerous commercial fish species. A conservation strategy should be implemented to safeguard the mangroves around the Egyptian Red Sea by using mitigation techniques, creating marine protected zones near the mangroves, and consulting the owners of the mangrove stalks. Analysis of multi-temporal satellite imagery is one of the most significant methods to assist decision-makers and environmental planners in obtaining high-precision information about environmental and climatic changes. Analysis of satellite imagery is a valuable way to detect, monitor, assess and map the environmental, human, and natural activities that are threatening the growth of the mangrove forest ecosystem. Change detection analyses using satellite imagery were conducted to evaluate the effects of rapid coastal sustainable development, including human urban and tourism activities; the decline and destruction of large areas of the mangrove forest for animal feeding along camel trade roads; and the threat of natural impacts such as flash flooding, coastal and soil erosion or human impacts such as established desalination plants and other human activities along the coastal zone of the Egyptian Red Sea.

Relation of the work ability index to fitness for work in healthcare and public employees in a region of Northeastern Italy - Federico Ronchese; Francesca Ricci; Giulia Peccolo; Benedetta Persechino; Bruna Maria Rondinone; Giuliana Buresti; Corrado Negro; Massimo Bovenzi; Andrea Miani (International Archives of Occupational and Environmental Health, 2023)
Purpose Work ability indicates an individual’s capacity to match job demands according to his/her physical and mental conditions and work circumstances. Occupational physicians should take into consideration the global health status of a worker in order to correctly assess if he/she is fit for the job. The aim of this study was to verify the association between fitness for work evaluation and Work Ability Index scores, as well as individual factors (age, gender, and anthropometric characteristics) and work-related variables (job type, years of working duration). Methods A cross-sectional study was conducted within the occupational health surveillance of health and public employers in the Friuli-Venezia Giulia region (2018–2022). The participants voluntarily agreed to answer the standard Work Ability Index questionnaire. Data were investigated by univariable as well as multivariable regression analysis. Results The Work Ability Index of the workers included in the study ( N = 6893) resulted negatively associated with age, female sex, and body mass index. It was averagely lower in nurses and assistive personnel, and the highest in medical doctors and public employers. The fitness for work assessments was also statistically related to WAI scores. The results obtained from the univariable and the multivariable analysis were consistent. Conclusions The Work Ability Index is an efficient tool to measure an individual’s capability to sustain job demands, and can be taken into account to produce a correct fitness for work evaluation and consequently preserve workers’ health status.

Biotic and abiotic factors affecting the microbiota of Chrysomelidae inhabiting wetland vegetation - Giulia Magoga; Matteo Brunetti; Lukasz Kajtoch; Alberto Spada; Matteo Montagna (Hydrobiologia, 2023)
A subject of particular interest concerns the understanding of which biotic and/or abiotic factors shape the insect’s microbiota composition and diversity. In this study, we focus our attention on the microbiota associated with leaf beetles (Coleoptera: Chrysomelidae) inhabiting a freshwater wetland in Northern Italy for investigating which factors shape it in this peculiar environment. A DNA metabarcoding approach targeting the 16S rRNA has been used to characterize the bacteria associated with seven leaf beetles species living in different zones of the wetland (trees/shrubs, meadow and emergent vegetation zones). The obtained results suggest that three factors potentially affecting microbiota diversity and composition are species membership in the first place, then living zone in the wetland and sex. Within the studied species, males were found possibly more prone to acquire bacteria from the surrounding environment, while females’ microbiota of most of the species resulted dominated by symbiotic bacteria (reproductive manipulators, e.g. Wolbachia , or other symbionts with functional roles in the species, e.g. Candidatus Macropleicola in Donacia genus). The present study, even if based on a limited sample size, contributed to exploring the factors affecting the composition and diversity of bacteria associated with Chrysomelidae.

Does pollinator conservation promote environmental co-benefits? - Andree Cappellari; Giacomo Ortis; Maurizio Mei; Dino Paniccia; Elisa Carrossa; Chiara Eccheli; Sara Facchetti; Giulia Lorenzon; Lorenzo Marini (Agriculture, Ecosystems & Environment, 2023)

Correction to: Weber Syndrome - Marina Romozzi; Giulia Bramato; Marco Luigetti (Acta Neurologica Belgica, 2023)

Evaluation of concentration procedures, sample pre-treatment, and storage condition for the detection of SARS-CoV-2 in wastewater - Francesca Cutrupi; Michele Rossi; Maria Cadonna; Elisa Poznanski; Serena Manara; Mattia Postinghel; Giulia Palumbi; Marta Bellisomi; Elena Nicosia; Giorgia Allaria; Lorenzo Dondero; Carolina Veneri; et al. (Environmental Science and Pollution Research, 2023)
Crucial information on the pandemic’s spread has been gathered by monitoring the trend of SARS-CoV-2 in wastewater. This surveillance has highlighted that the initial concentration is a critical step of the analytical procedure due to the low viral titer that may be present in this matrix. This paper presents the results of the evaluation of two different wastewater concentration protocols to determine the most efficient and cost-effective. The two methods tested were the following: (a) a biphasic separation system with PEG-dextran and (b) a PEG/NaCl precipitation protocol. Other aspects of the detection method were also investigated including the influence of storage temperature on virus recovery and the heat treatment of pasteurization, which aims to make samples safer for operators and the environment. The PEG/NaCl precipitation method was found to perform better than the biphasic separation system, allowing for more sensitive identification of the presence of the virus and the detection of a higher viral titer than that identified with the biphasic separation in all results. Storage of the samples at 4.3±0.2°C for up to 3 weeks did not adversely affect the virus titer and the pasteurization pre-treatment increases operator safety and maintains the identification of the viral concentration. Graphical abstract

Atrazine and its degradation products in drinking water source and supply: Risk assessment for environmental and human health in Campinas, Brazil - Beatriz De Caroli Vizioli; Giulia Silva da Silva; Jéssyca Ferreira de Medeiros; Cassiana Carolina Montagner (Chemosphere, 2023)

Vulnerability to overfishing of fish stocks in the Amazon Basin - Diego V. Pereira; Marcos de A. Mereles; Octávio F. de Matos; Giulia Cristina dos S. Lopes; Katrine G. da Conceição; Carlos Edwar de C. Freitas (Fisheries Research, 2023)

Immune-Mediated Hemolytic Anemia and Clinically Suspected Acute Pancreatitis in Dogs, a Pilot Study - Giulia Gianesini; Michele Drigo; Andrea Zoia (Topics in Companion Animal Medicine, 2023)

On the legacy of cover crop-specific microbial footprints - Sara Giulia Cazzaniga; Sven van den Elsen; Carin Lombaers; Marc Kroonen; Johnny Visser; Joeke Postma; Liesje Mommer; Johannes Helder (Soil Biology and Biochemistry, 2023)

Proteomics coupled with AhR-reporter gene bioassay for human and environmental safety assessment of sewage sludge and hydrochar - Claudia Landi; Giulia Liberatori; Monica Puccini; Enxhi Shaba; Lorenza Vantaggiato; Sandra Vitolo; Ilaria Corsi; Luca Bini (Science of The Total Environment, 2023)

MicroRNA as epigenetic regulators of canine cryptorchidism - Giulia Pizzi; Debora Groppetti; Eleonora Brambilla; Alessandro Pecile; Valeria Grieco; Cristina Lecchi (Research in Veterinary Science, 2023)

The dawn of the Late Villafranchian: Paleoenvironment and age of the Pantalla paleontological site (Italy; Early Pleistocene) - Marco Cherin; Giorgio Basilici; Mathieu Duval; Qingfeng Shao; Mark J. Sier; Josep M. Parés; Elsa Gliozzi; Ilaria Mazzini; Donatella Magri; Federico Di Rita; Dawid A. Iurino; Beatrice Azzarà; et al. (Quaternary Science Reviews, 2023)

Late Neanderthal “menu” from northern to southern Italy: freshwater and terrestrial animal resources - Matteo Romandini; Sara Silvestrini; Cristina Real; Federico Lugli; Laura Tassoni; Lisa Carrera; Federica Badino; Eugenio Bortolini; Giulia Marciani; Davide Delpiano; Marcello Piperno; Carmine Collina; et al. (Quaternary Science Reviews, 2023)

Evaluating the taxonomic status of the large sized Tricolia Risso, 1826 in the Northeast Atlantic and Mediterranean Sea - Lara Baptista; Giulia Fassio; Serge Gofas; Marco Oliverio; Sérgio P. Ávila; António M. Santos (Molecular Phylogenetics and Evolution, 2023)

Hidden species diversity and mito-nuclear discordance within the Mediterranean cone snail, Lautoconus ventricosus - Samuel Abalde; Fabio Crocetta; Manuel J. Tenorio; Salvatore D'Aniello; Giulia Fassio; Paula C. Rodríguez-Flores; Juan E. Uribe; Carlos M.L. Afonso; Marco Oliverio; Rafael Zardoya (Molecular Phylogenetics and Evolution, 2023)

Altered lipid acyl chain length controls energy dissipation in light-harvesting complex II proteoliposomes by hydrophobic mismatch - Dan-Hong Li; Sam Wilson; Giulia Mastroianni; Alexander V. Ruban (Journal of Photochemistry and Photobiology B: Biology, 2023)

Distribution and prevalence of viral genomes in Italian populations of the invasive brown marmorated stink bug Halyomorpha halys - Giulia Papa; Simona Abbà; Luciana Galetto; Cecilia Parise; Cristina Marzachì; Ilaria Negri (Journal of Invertebrate Pathology, 2023)

Sustainable aviation fuel production using in-situ hydrogen supply via aqueous phase reforming: A techno-economic and life-cycle greenhouse gas emissions assessment - Giuseppe Pipitone; Giulia Zoppi; Raffaele Pirone; Samir Bensaid (Journal of Cleaner Production, 2023)

Supporting the planning of urban blue-green infrastructure for biodiversity: A multi-scale prioritisation framework - Francesc Molné; Giulia F.A. Donati; Janine Bolliger; Manuel Fischer; Max Maurer; Peter M. Bach (Journal of Environmental Management, 2023)

Indulgent or informative logos? Effects on university students’ intention to purchase healthy and sustainable food - Giulia Andreani; Giovanni Sogari; Rungsaran Wongprawmas; Davide Menozzi; Cristina Mora (International Journal of Gastronomy and Food Science, 2023)

Salivary microbial profiles associate with responsiveness to warning oral sensations and dietary intakes - Leonardo Menghi; Danny Cliceri; Francesca Fava; Massimo Pindo; Giulia Gaudioso; Davide Giacalone; Flavia Gasperi (Food Research International, 2023)

An international investigation of chlorinated paraffin concentrations and homologue distributions in indoor dust - Thomas J. McGrath; Giulia Poma; Sébastien Hutinet; Yukiko Fujii; Robin E. Dodson; Boris Johnson-Restrepo; Dudsadee Muenhor; Gaud Dervilly; Ronan Cariou; Adrian Covaci (Environmental Pollution, 2023)

Nanoplastic exposure inhibits feeding and delays regeneration in a freshwater planarian - Giulia Cesarini; Francesca Coppola; Diana Campos; Iole Venditti; Chiara Battocchio; Andrea Di Giulio; Maurizio Muzzi; João L.T. Pestana; Massimiliano Scalici (Environmental Pollution, 2023)

Structural and functional damage to the retina and skeletal muscle in Xenopus laevis embryos exposed to the commonly used psychotropic benzodiazepine delorazepam - Chiara Fogliano; Rosa Carotenuto; Giulia Rusciano; Antonio Sasso; Chiara Maria Motta; Claudio Agnisola; Bice Avallone (Environmental Toxicology and Pharmacology, 2023)

Investigating the effects of climate on thermal adaptation: A comparative field study in naturally ventilated university classrooms - Giulia Lamberti; Francesco Leccese; Giacomo Salvadori; Francesca Contrada; Andrea Kindinis (Energy and Buildings, 2023)

ERO1α primes the ryanodine receptor to respond to arsenite with concentration dependent Ca2+ release sequentially triggering two different mechanisms of ROS formation - Andrea Guidarelli; Andrea Spina; Gloria Buffi; Giulia Blandino; Mara Fiorani; Orazio Cantoni (Chemico-Biological Interactions, 2023)

Clinical use of the canine foetal kidney formula in dogs of different maternal sizes during the last ten days before parturition - Giulia Siena; Francesca di Nardo; Barbara Contiero; Chiara Milani (Veterinary Research Communications, 2023)

Translocations of threatened plants in the Mediterranean Basin: current status and future directions - Giuseppe Fenu; Giulia Calderisi; Igor Boršić; Magda Bou Dagher Kharrat; Alfredo García Fernández; Rhea Kahale; Maria Panitsa; Donatella Cogoni (Plant Ecology, 2023)
The Mediterranean Basin is one of the World’s plant diversity hotspots and a region prone to several anthropic pressures, besides being one of the World’s areas most susceptible to climate change. In this region, which hosts a high percentage of threatened species, there has been a large increase in practical conservation actions to prevent the extinction of many plants or improve their conservation status. In this framework, plant translocations have become increasingly important. To obtain a picture of the status and to depict possible directions, data on plant translocations was collected through the available databases, national experts, and the grey literature available online. Overall, a list of 836 translocations relating to 572 plant species was found. These actions are mainly concentrated in Spain, France, and Italy (c. 87%) and, except for some pioneering actions, translocations have strongly increased starting from 2010. A subsequent in-depth bibliographic search of the scientific databases was conducted to determine how much information about plant translocations was documented in the scientific literature. This search resulted in a list of 133 peer-reviewed papers, of which only 17 describing one or more translocations and, as a whole, reporting 101 experiences carried out on 56 plant species. Our research highlighted a great discrepancy between the scarce scientific documentation in comparison to the large number of practical conservation actions carried out. The great experience gained in these translocations constitutes an enormous heritage potentially available to implement the necessary conservation actions to preserve the plant diversity of the Mediterranean Basin.

Anthropogenic hybridization and its influence on the adaptive potential of the Sardinian wild boar (Sus scrofa meridionalis) - Giulia Fabbri; Ludovica Molinaro; Nadia Mucci; Luca Pagani; Massimo Scandura (Journal of Applied Genetics, 2023)
The wild boar ( Sus scrofa meridionalis ) arrived in Sardinia with the first human settlers in the early Neolithic with the potential to hybridize with the domestic pig ( S. s. domesticus ) throughout its evolution on the island. In this paper, we investigated the possible microevolutionary effects of such introgressive hybridization on the present wild boar population, comparing Sardinian wild specimens with several commercial pig breeds and Sardinian local pigs, along with a putatively unadmixed wild boar population from Central Italy, all genotyped with a medium density SNP chip. We first aimed at identifying hybrids in the population using different approaches, then examined genomic regions enriched for domestic alleles in the hybrid group, and finally we applied two methods to find regions under positive selection to possibly highlight instances of domestic adaptive introgression into a wild population. We found three hybrids within the Sardinian sample (3.1% out of the whole dataset). We reported 11 significant windows under positive selection with a method that looks for overly differentiated loci in the target population, compared with other two populations. We also identified 82 genomic regions with signs of selection in the domestic pig but not in the wild boar, two of which overlapped with genomic regions enriched for domestic alleles in the hybrid pool. Genes in these regions can be linked with reproductive success. Given our results, domestic introgression does not seem to be pervasive in the Sardinian wild boar. Nevertheless, we suggest monitoring the possible spread of advantageous domestic alleles in the coming years.

Consumer Role in Closing the Loop in the Apparel Industry Towards Circular Systems - Giulia Villas Boas Fiori; Marina Bouzon; Jaqueline Carneiro Kerber (Circular Economy and Sustainability, 2023)

Zebrafish as a model for cardiac disease; Cryo-EM structure of native cardiac thin filaments from Danio Rerio - Marston Bradshaw; John M. Squire; Edward Morris; Georgia Atkinson; Rebecca Richardson; Jon Lees; Massimo Caputo; Giulia M. Bigotti; Danielle M. Paul (Journal of Muscle Research and Cell Motility, 2023)
Actin, tropomyosin and troponin, the proteins that comprise the contractile apparatus of the cardiac thin filament, are highly conserved across species. We have used cryo-EM to study the three-dimensional structure of the zebrafish cardiac thin and actin filaments. With 70% of human genes having an obvious zebrafish orthologue, and conservation of 85% of disease-causing genes, zebrafish are a good animal model for the study of human disease. Our structure of the zebrafish thin filament reveals the molecular interactions between the constituent proteins, showing that the fundamental organisation of the complex is the same as that reported in the human reconstituted thin filament. A reconstruction of zebrafish cardiac F-actin demonstrates no deviations from human cardiac actin over an extended length of 14 actin subunits. Modelling zebrafish homology models into our maps enabled us to compare, in detail, the similarity with human models. The structural similarities of troponin-T in particular, a region known to contain a hypertrophic cardiomyopathy ‘hotspot’, confirm the suitability of zebrafish to study these disease-causing mutations.

One-Year Follow-Up on Essential Tremor Worsening After SARS-CoV-2 Infection: a Series of Two Cases - Davide Costa; Daniele Birreci; Massimiliano Passaretti; Luca Angelini; Donato Colella; Antonio Cannavacciuolo; Giulia Paparella; Alfredo Berardelli; Matteo Bologna (The Cerebellum, 2023)

Comparison of Two Therapeutic Approaches of Cerebellar Transcranial Direct Current Stimulation in a Sardinian Family Affected by Spinocerebellar Ataxia 38: a Clinical and Computerized 3D Gait Analysis Study - Angela Sanna; Massimiliano Pau; Giuseppina Pilia; Micaela Porta; Giulia Casu; Valentina Secci; Emanuele Cartella; Alessandro Demattia; Stefano Firinu; Chiara Pau; Antonio Milia; Eleonora Cocco; et al. (The Cerebellum, 2023)

Impaired reproduction, energy reserves and dysbiosis: The overlooked consequences of heatwaves in a bivalve mollusc - Luca Peruzza; Carmen Federica Tucci; Riccardo Frizzo; Tobia Riello; Andrea Quagliariello; Maria Elena Martino; Alice Manuzzi; Giulia Dalla Rovere; Federico Bonsembiante; Maria Elena Gelain; Morgan Smits; Oliviero Borgheresi; et al. (Marine Pollution Bulletin, 2023)

New ecological frontiers in the plastisphere: Diatoms and macroinvertebrates turnover assessment by a traits-based approach - Davide Taurozzi; Giulia Cesarini; Massimiliano Scalici (Science of The Total Environment, 2023)

Benthic foraminiferal response to the Oceanic Anoxic Event 2 (Late Cretaceous) and evidence of bottom water re‐oxygenation during the Plenus Cold Event at Clot Chevalier (Vocontian Basin, SE France) - Giulia Amaglio; Maria Rose Petrizzo; Ann Holbourn; Wolfgang Kuhnt; Erik Wolfgring (Palaeogeography, Palaeoclimatology, Palaeoecology, 2023)

Corrigendum to “A DNA-structured mathematical model of cell-cycle progression in cyclic hypoxia” [J. Theor. Biol. 545 (2022) 111104] - Giulia L. Celora; Samuel B. Bader; Ester M. Hammond; Philip K. Maini; Joe M. Pitt-Francis; Helen M. Byrne (Journal of Theoretical Biology, 2023)

Reusing drainage water and substrate to improve the environmental and economic performance of Mediterranean greenhouse cropping - Oriana Gava; Assumpció Antón; Giulia Carmassi; Alberto Pardossi; Luca Incrocci; Fabio Bartolini (Journal of Cleaner Production, 2023)

Origin of non-exhaust PM in cities by individual analysis of particles collected by honey bees (Apis mellifera) - Marco Pellecchia; Giulia Papa; Mario Barbato; Giancarlo Capitani; Ilaria Negri (Environmental Pollution, 2023)

Metal pollution in freshwater fish: A key indicator of contamination and carcinogenic risk to public health - Bibhu Prasad Panda; Yugal Kishore Mohanta; Siba Prasad Parida; Abanti Pradhan; Tapan Kumar Mohanta; Kaustuvmani Patowary; Wan Adibah Wan Mahari; Su Shiung Lam; Ayman A. Ghfar; Giulia Guerriero; Meenakshi Verma; Hemen Sarma (Environmental Pollution, 2023)

Designing successful agri-environmental schemes: A mechanistic analysis of a collective scheme for eco-system services in the Netherlands - Giulia Bazzan; Jeroen Candel; Carsten Daugbjerg (Environmental Science & Policy, 2023)

Energy, SBS symptoms, and productivity in Swiss open-space offices: Economic evaluation of standard, actual, and optimum scenarios - Dolaana Khovalyg; Cecile A. Berquand; Giulia Vergerio; Verena M. Barthelmes; Arnab Chatterjee; Cristina Becchio; Dusan Licina (Building and Environment, 2023)

Proteomic Profiling Reveals Specific Molecular Hallmarks of the Pig Claustrum - Andrea Pirone; Federica Ciregia; Giulia Lazzarini; Vincenzo Miragliotta; Maurizio Ronci; Mariachiara Zuccarini; Lorenzo Zallocco; Daniela Beghelli; Maria Rosa Mazzoni; Antonio Lucacchini; Laura Giusti (Molecular Neurobiology, 2023)
The present study, employing a comparative proteomic approach, analyzes the protein profile of pig claustrum (CLA), putamen (PU), and insula (IN). Pig brain is an interesting model whose key translational features are its similarities with cortical and subcortical structures of human brain. A greater difference in protein spot expression was observed in CLA vs PU as compared to CLA vs IN. The deregulated proteins identified in CLA resulted to be deeply implicated in neurodegenerative (i.e., sirtuin 2, protein disulfide-isomerase 3, transketolase) and psychiatric (i.e., copine 3 and myelin basic protein) disorders in humans. Metascape analysis of differentially expressed proteins in CLA vs PU comparison suggested activation of the α-synuclein pathway and L1 recycling pathway corroborating the involvement of these anatomical structures in neurodegenerative diseases. The expression of calcium/calmodulin-dependent protein kinase and dihydropyrimidinase like 2, which are linked to these pathways, was validated using western blot analysis. Moreover, the protein data set of CLA vs PU comparison was analyzed by Ingenuity Pathways Analysis to obtain a prediction of most significant canonical pathways, upstream regulators, human diseases, and biological functions. Interestingly, inhibition of presenilin 1 (PSEN1) upstream regulator and activation of endocannabinoid neuronal synapse pathway were observed. In conclusion, this is the first study presenting an extensive proteomic analysis of pig CLA in comparison with adjacent areas, IN and PUT. These results reinforce the common origin of CLA and IN and suggest an interesting involvement of CLA in endocannabinoid circuitry, neurodegenerative, and psychiatric disorders in humans.

Correlation analysis between auto-immunological and mutational profiles in myelodysplastic syndromes - Antonio Cristiano; Riccardo Belardi; Hajro Hajrullaj; Emiliano Fabiani; Giulia Falconi; Elisa Galossi; Sergio Bernardini; Maria Teresa Voso; Marzia Nuccetelli (Inflammation Research, 2023)
Objective and design Systemic-Inflammatory-Autoimmune-Diseases (SIAD) is increasingly considered in Myelodysplastic-Syndromes (MDS). In this line, we evaluated the MDS auto-immunological profile, correlating it to the mutational landscape, trying to identify a molecular-genetic trigger agent related to SIAD. Methods and materials Eighty-one MDS were enrolled and t-NGS was performed. Anti-Nuclear-Antibodies (ANA) were tested, and ANA-antigenic-specificity was characterized by ANA-profile, ENA-screen, anti-dsDNA. Non-Hematological-Patients (NHP) and Healthy-Donors (HD) were used as controls. Results At clinically relevant cut-off (≥ 1:160), ANA was significantly more frequent in MDS, while ANA-antigenic-specificity showed a low association rate. ANA ≥ 1:160-positive MDS showed a mutational landscape similar to ANA-negative/ANA < 1:160 MDS. No significant correlations between mutational and immunological profiles were found and UBA1 mutations, related to VEXAS, were absent. Conclusions Although ANA-positivity was found to be increased in MDS, the low ANA-antigenic-specificity suggests that autoantibodies didn’t recognize autoimmune-pathognomonic antigens. The lack of relationship between genetic profile and ANA-positivity, suggests that MDS genetic variants may not be the direct cause of SIAD.

3D bioprinted scaffolds for diabetic wound-healing applications - Katie Glover; Essyrose Mathew; Giulia Pitzanti; Erin Magee; Dimitrios A. Lamprou (Drug Delivery and Translational Research, 2023)
The treatment strategy required for the effective healing of diabetic foot ulcer (DFU) is a complex process that is requiring several combined therapeutic approaches. As a result, there is a significant clinical and economic burden associated in treating DFU. Furthermore, these treatments are often unsuccessful, commonly resulting in lower-limb amputation. The use of drug-loaded scaffolds to treat DFU has previously been investigated using electrospinning and fused deposition modelling (FDM) 3D printing techniques; however, the rapidly evolving field of bioprinting is creating new opportunities for innovation within this research area. In this study, 3D-bioprinted scaffolds with different designs have been fabricated for the delivery of an antibiotic (levoflocixin) to DFU. The scaffolds were fully characterised by a variety of techniques (e.g. SEM, DSC/TGA, FTIR, and mechanical characterisation), demonstrating excellent mechanical properties and providing sustained drug release for 4 weeks. This proof of concept study demonstrates the innovative potential of bioprinting technologies in fabrication of antibiotic scaffolds for the treatment of DFU. Graphical abstract

In vivo evaluation of nanostructured lipid carrier systems (NLCs) in mice bearing prostate cancer tumours - Mushfiq Akanda; Giulia Getti; Dennis Douroumis (Drug Delivery and Translational Research, 2023)
Nanostructure lipid carriers (NLCs) were developed for the delivery of curmumin (CRN), a potent anticancer agent with low bioavailability, for the treatment of prostate cancer. NLCs prepared using high pressure homogenization (HPH) with around 150 nm particle size, − 40 V ζ-potential and excellent long-term stability. Cellular uptake of CRN-SLN showed nanoparticle localization in the cytoplasm around the nucleus. CRN-NLCs were assessed using flow cytometry and found to cause early and late apoptotic events at 100 μg/ml CRN concentrations. CRN-NLC nanoparticles were administrated to nude mice with LNCaP prostate cancer xenografts and demonstrated substantial tumour volume suppression (40%) with no weight loss compared to pure CRN (ethanolic solution). Overall, NLCs were proved a suitable carrier for passive drug delivery and cancer treatment. Graphical abstract

Experimental Semiotics: A Systematic Categorization of Experimental Studies on the Bootstrapping of Communication Systems - Angelo Delliponti; Renato Raia; Giulia Sanguedolce; Adam Gutowski; Michael Pleyer; Marta Sibierska; Marek Placiński; Przemysław Żywiczyński; Sławomir Wacewicz (Biosemiotics, 2023)
Experimental Semiotics (ES) is the study of novel forms of communication that communicators develop in laboratory tasks whose designs prevent them from using language. Thus, ES relates to pragmatics in a “pure,” radical sense, capturing the process of creating the relation between signs and their interpreters as biological, psychological, and social agents. Since such a creation of meaning-making from scratch is of central importance to language evolution research, ES has become the most prolific experimental approach in this field of research. In our paper, we report the results of a study on the scope of recent ES and evaluate the ways in which it is relevant to the study of language origins. We coded for multiple levels across 13 dimensions related to the properties of the emergent communication systems or properties of the study designs, such as type of goal ( coordination versus referential ), modality of communication, absence or presence of turn-taking , or the presence of vertical vs. horizontal transmission . We discuss our findings and our classification, focusing on the advantages and limitations of those trends in ES, and in particular their ecological validity in the context of bootstrapping communication and the evolution of language.

Innovative thermally assisted on-line solid phase extraction-reversed phase liquid chromatography applied to targeted nutrimetabolomics in human biofluids - Lapo Renai; Luca Marzullo; Giulia Bonaccorso; Serena Orlandini; Fulvio Mattivi; Maria Concetta Bruzzoniti; Massimo Del Bubba (Analytica Chimica Acta, 2023)

Outcomes of a comparison between pastoral and silvopastoral management on beef cattle productivity, animal welfare and pasture depletion in a Mediterranean extensive farm - Alice Ripamonti; Alberto Mantino; Francesco Annecchini; Alice Cappucci; Laura Casarosa; Luca Turini; Giulia Foggi; Marcello Mele (Agroforestry Systems, 2023)
In spring 2021, 50 growing steers and heifers of the Maremmana breed (average age 321 d and weight 287 kg) were rotationally stocked under two different treatments (silvopastoral and pastoral). The aim was to evaluate the influence of grazing system on cattle growth and welfare, and pasture depletion. The experiment was carried out on a real Mediterranean agrosilvopastoral farm, located in central Italy. To implement rotational grazing, 3.69 ha of temporary grassland were split into six paddocks, three for each treatment. Cattle grazed for one week in one paddock and then were moved to the next one for a total of six weeks corresponding to six grazing periods. The group maintained on the silvopastoral system were allowed to access 3.31 ha of a Turkey oak ( Quercus cerris L.) forest. Regarding the average daily gain, a significant interaction was found between the treatment and time. The average daily gain of the animals grazing in the open pasture was 1.20 kg d −1 , while that of the cattle grazing in the silvopastoral system was 1.02 kg d −1 . Despite the rate of growth being within the expected range for the Maremmana breed, the average daily gain of cattle in the silvopastoral system was significantly lower. One of the possible causes of this difference could be the higher energy requirements of the animals due to the different activity levels. The different management did not affect animal welfare indicators. Indeed, the serum cortisol concentration did not vary between treatments and among sampling times, while the hair cortisol concentration decreased significantly during the experiment for both groups. Regarding pasture health, allowing cattle to graze in the forest reduced pasture depletion because of the lower stocking rate and grazing pressure. Further studies are necessary to increase the knowledge of the role of forests and grazing management in other seasons than spring in extensive agrosilvopastoral systems.

Quantifying irrigation uptake in olive trees: a proof-of-concept approach combining isotope tracing and Hydrus-1D - Paolo Nasta; Diego Todini-Zicavo; Giulia Zuecco; Chiara Marchina; Daniele Penna; Jeffrey J. McDonnell; Anam Amin; Carolina Allocca; Fabio Marzaioli; Luisa Stellato; Marco Borga; Nunzio Romano (Hydrological Sciences Journal, 2023)

Circular economy in the valorisation of food and other biowaste: case studies in small and medium-sized enterprises in the Belgian construction sector - Giulia Scialpi; Daniela Perrotti (Environmental Science and Pollution Research, 2023)

Plastic impurities in biowaste treatment: environmental and economic life cycle assessment of a composting plant - Sara Bottausci; Chiara Magrini; Giulia Adele Tuci; Alessandra Bonoli (Environmental Science and Pollution Research, 2023)
The study focuses on an Italian composting plant and aims to investigate the impact of the presence of plastic impurities in the collected biowaste on the environmental and economic performance of the plant. The study is divided into two main steps: firstly, a material flow analysis was conducted to quantify the number of impurities (e.g., conventional plastics and compostable plastics) before and after the composting process. Secondly, a life cycle assessment (LCA) and a complementary life cycle costing (LCC) of the composting process were conducted. The results of the material flow analysis confirmed the initial assumption that conventional plastic remains almost constant before and after the composting treatment, while compostable plastic almost disappears. As far as the life cycle analyses are concerned, the most environmentally damaging phases of the process were the shredding and mixing phases, while the operating costs (OPEX) contributed the most to the total annual costs of the company. Finally, a further scenario analysis was performed, assuming that the plastic contaminants in the treated biowaste consisted exclusively of compostable plastics. The comparison with this ideal scenario can support decision-makers to understand the potential improvements achievable by addressing the presence of plastic impurities in the biowaste. The results show that the treatment of plastic impurities causes relevant environmental and economic impacts, being responsible for 46% of the total waste to treat at the end of the process, almost 7% of the total annual costs covered by the plant owners, and about 30% of all negative externalities.

Tree tracking: species selection and traceability for sustainable and biodiversity-friendly urban reforestation - Jessica Frigerio; Giulia Capotorti; Eva Del Vico; Malika Ouled Larbi; Fabrizio Grassi; Carlo Blasi; Massimo Labra; Werther Guidi Nissim (Plant Biosystems, 2023)

Low-power networks and GIS analyses for monitoring the site use of grazing cattle - Dominga Mancuso; Giulia Castagnolo; Monica C.M. Parlato; Francesca Valenti; Simona M.C. Porto (Computers and Electronics in Agriculture, 2023)

Difference between invasive alien and native vegetation in trapping beach litter: A focus on a typical sandy beach of W-Mediterranean Basin - Giulia Calderisi; Donatella Cogoni; Alessandra Loni; Giuseppe Fenu (Marine Pollution Bulletin, 2023)

Corrigendum to: “Variations of sedimentary Fe and Mn fractions under changing lake mixing regimes, oxygenation and land surface processes during Late-glacial and Holocene times” [Sci. Total Environ. 755 (2021) 143418] - Stamatina Makri; Giulia Wienhues; Moritz Bigalke; Adrian Gilli; Fabian Rey; Willy Tinner; Hendrik Vogel; Martin Grosjean (Science of The Total Environment, 2023)

Challenges in studying water fluxes within the soil-plant-atmosphere continuum: A tracer-based perspective on pathways to progress - Natalie Orlowski; Michael Rinderer; Maren Dubbert; Natalie Ceperley; Markus Hrachowitz; Arthur Gessler; Youri Rothfuss; Matthias Sprenger; Ingo Heidbüchel; Angelika Kübert; Matthias Beyer; Giulia Zuecco; et al. (Science of The Total Environment, 2023)

Into the backyard: Multiple detections of PCV-2e in rural pig farms of Northern Italy. An unexpected ecological niche? - Giulia Faustini; Claudia Maria Tucciarone; Matteo Legnardi; Laura Grassi; Giacomo Berto; Michele Drigo; Mattia Cecchinato; Giovanni Franzo (Preventive Veterinary Medicine, 2023)

A review on ship motions and quiescent periods prediction models - Giulia Cademartori; Luca Oneto; Federica Valdenazzi; Andrea Coraddu; Andrea Gambino; Davide Anguita (Ocean Engineering, 2023)

Profile of calls and activities of the first Teratogen Information Service in Latin America through 32 years - Lavínia Schuler-Faccini; Maria Teresa V. Sanseverino; Sacha Krolow e Silva; Camila P. Barbosa; Danton S. Ordovás; Carolina S. Arashiro; Ricardo Rohweder; Ana Paula Ornaghi; Filipe M. Sanchez; Giulia Radin; Victoria L.S. Gomes; Lucas M. Pires; et al. (Neurotoxicology and Teratology, 2023)

Elastic thermobarometry of ultrahigh-pressure metapelites from the Brossasco-Isasca Unit (Dora-Maira Massif, Western Alps) - Giulia Mingardi; Nicola Campomenosi; Mattia Gilio; Christian Chopin; Marco Scambelluri; Matteo Alvaro (Lithos, 2023)

Re: Yang et al., Arsenic exposures and prostate cancer risk: A multilevel meta-analysis [J. Trace Elem. Med. Biol. (2022) 72 126992] - Paolo Boffetta; Giulia Collatuzzo; Samuel M. Cohen (Journal of Trace Elements in Medicine and Biology, 2023)

Assessment of natural capital and environmental flows distribution: A Mediterranean case study - Rachele Bordoni; Ilaria Rigo; Giulia Dapueto; Paolo Povero; Paolo Vassallo; Chiara Paoli (Journal of Cleaner Production, 2023)

Effects of oral exposure to brake wear particulate matter on the springtail Orthonychiurus folsomi - Giulia Papa; Karen Power; Bartolo Forestieri; Giancarlo Capitani; Paola Maiolino; Ilaria Negri (Environmental Pollution, 2023)

Comparative analysis of the thermal insulation performance of a façade enclosure integrated by vegetation under simultaneous windy and rainy climatic conditions - Elvira Nicolini; Francesca Olivieri; Maria Luisa Germanà; Giulia Marcon; Marcello Chiodi; Lorenzo Olivieri (Building and Environment, 2023)

Iron from Lignite Mining Increases Phosphorus Fixation in Sediments, but Does Not Affect Trophic States of Lakes Along River Spree (Germany) - Giulia Kommana; Björn Grüneberg; Michael Hupfer (Water, Air, & Soil Pollution, 2023)
To mitigate lake eutrophication, phosphorus (P) availability can be managed by iron (Fe) amendments, which bind P in the water column and settle as Fe oxy-hydroxides. In the fluvial-lacustrine system Spree, Fe oxy-hydroxides enter lakes due to lignite mining in the Lusatian Area (NE Germany). We hypothesized that the amount of P that can be retained from the water column by sediments is positively correlated with their iron content. Column experiments were used to investigate uptake and release of P in the sediments under oxic and anoxic conditions in three downstream lakes (Lake Neuendorfer See, Lake Glower See, Lake Müggelsee) with decreasing mining influence and thus iron loads, and one nearby non-mining-affected lake (Lake Schwielochsee). In lakes interconnected by River Spree, the cumulative P uptake in sediments increased significantly with increasing sedimentary Fe concentrations under both oxic and anoxic conditions. Only the sediments of Lake Glower See had higher P uptake under anoxic than oxic conditions, most likely due to vivianite formation. The net P sedimentation was higher with higher Fe concentration and higher under oxic than anoxic conditions. However, the lakes are classified as eutrophic because although the sediments of the Spree lakes can store further P, this additional P uptake is of little relevance for the P budget in highly P-loaded lakes with short water residence times (10–100 d), as is typical for fluvial-lacustrine systems.

Semi-continuous production of polyhydroxybutyrate (PHB) in the Chlorophyta Desmodesmus communis - Laura Pezzolesi; Chiara Samorì; Giorgia Zoffoli; Giulia Xamin; Mara Simonazzi; Rossella Pistocchi (Algal Research, 2023)

Using just a canopy height model to obtain lidar-level accuracy in 3D forest canopy shortwave transmissivity estimates - Clare Webster; Richard Essery; Giulia Mazzotti; Tobias Jonas (Agricultural and Forest Meteorology, 2023)

Satellite tracking identifies important foraging areas for loggerhead turtles frequenting the Adriatic Sea, Central Mediterranean - RESI MENCACCI; LAURA AIUDI; VALERIA ANGELINI; PAOLO CASALE; GIULIA CERRITELLI; KAMYLA LOMBARDI MORAES; SAURO PARI; Paolo Luschi (Mediterranean Marine Science, 2023)
The Adriatic Sea is one of the main foraging areas for marine turtles of the Mediterranean Sea, but the specific high-use sites are poorly known, due to the scarceness of satellite tracking data available for juvenile turtles frequenting the area. In the present study, we tracked 8 juvenile and adult loggerhead turtles (Caretta caretta) that were released along the north-western Adriatic coast after a rehabilitation period having been equipped with Argos-linked satellite transmitters. Tracked turtles displayed quite variable movement patterns, but mostly remained in the north-western Adriatic, especially during the summer months. A marked preference for specific coastal sites was revealed in many turtles, that actively moved towards these specific locations when released south of it or having spent the winter away. Pooling these data with those obtained in previous studies on a further 10 turtles, we highlighted the presence of two main high-use areas, north and south of the Po River delta, where future conservation actions may then be focused.

The Predictive Role of the Posterior Cerebellum in the Processing of Dynamic Emotions - Gianluca Malatesta; Anita D’Anselmo; Giulia Prete; Chiara Lucafò; Letizia Faieta; Luca Tommasi (The Cerebellum, 2023)
Recent studies have bolstered the important role of the cerebellum in high-level socio-affective functions. In particular, neuroscientific evidence shows that the posterior cerebellum is involved in social cognition and emotion processing, presumably through its involvement in temporal processing and in predicting the outcomes of social sequences. We used cerebellar transcranial random noise stimulation (ctRNS) targeting the posterior cerebellum to affect the performance of 32 healthy participants during an emotion discrimination task, including both static and dynamic facial expressions (i.e., transitioning from a static neutral image to a happy/sad emotion). ctRNS, compared to the sham condition, significantly reduced the participants’ accuracy to discriminate static sad facial expressions, but it increased participants’ accuracy to discriminate dynamic sad facial expressions. No effects emerged with happy faces. These findings may suggest the existence of two different circuits in the posterior cerebellum for the processing of negative emotional stimuli: a first-time-independent mechanism which can be selectively disrupted by ctRNS, and a second time-dependent mechanism of predictive "sequence detection" which can be selectively enhanced by ctRNS. This latter mechanism might be included among the cerebellar operational models constantly engaged in the rapid adjustment of social predictions based on dynamic behavioral information inherent to others’ actions. We speculate that it might be one of the basic principles underlying the understanding of other individuals’ social and emotional behaviors during interactions.

Accumulation and release of organic pollutants by conventional and biodegradable microplastics in the marine environment - Camilla Catarci Carteny; Elvio Diego Amato; Fabienne Pfeiffer; Christina Christia; Nicolas Estoppey; Giulia Poma; Adrian Covaci; Ronny Blust (Environmental Science and Pollution Research, 2023)

Seasonal variability of the HO.RE.CA. food leftovers employed as a feeding substrate for black soldier fly (Hermetia illucens L.) larvae and effects on the rearing performance - Giuseppe Montevecchi; Laura Ioana Macavei; Elena Zanelli; Giacomo Benassi; Giulia Pinotti; Sara D'Arco; Silvia Buffagni; Francesca Masino; Lara Maistrello; Andrea Antonelli (Sustainable Chemistry and Pharmacy, 2023)

Heterogeneous characteristics and absorption enhancement of refractory black carbon in an urban city of China - Shuoyuan Chen; Qiyuan Wang; Yong Zhang; Jie Tian; Jin Wang; Steven Sai Hang Ho; Li Li; Weikang Ran; Yongming Han; Giulia Pavese; Junji Cao (Science of The Total Environment, 2023)

Marine strategy framework for detecting mass mortality: From local surveys to monitoring improvements in the coralligenous habitat - Luca Bisanti; Giulia Visconti; Marco Toccaceli; Antonino Bono; Renato Chemello (Regional Studies in Marine Science, 2023)

Morphological and functional alterations in hemocytes of Mytilus galloprovincialis exposed in high-impact anthropogenic sites - Antonio Calisi; Maria Elena Giordano; Francesco Dondero; Maria Maisano; Salvatore Fasulo; Maria Giulia Lionetto (Marine Environmental Research, 2023)

Follicular fluid and plasma concentrations of progesterone following hCG administration before ultrasound-guided ablation of dominant follicles ≥25mm in mares - Fernanda S Ignácio; Don R Bergfelt; Heloisa S Canesin; Giovana S Camargo; Giulia VR Lopes; Gabriel A Monteiro; Cezinande Meira (Journal of Equine Veterinary Science, 2023)

Induced ovulation and timed recovery of suitably sized embryos for transfer in mares - Giulia V Lopes; Giovana S Camargo; Giovanna N Sambi; Karina R Assoni; Renan Denadai; Don R Bergfelt; Heloisa S Canesin; Gabriel A Monteiro; Fernanda S Ignácio (Journal of Equine Veterinary Science, 2023)

Equine blastocyst re-expansion rate, quality, and sex following embryonic collapse using needle perforation of blastocoel and subsequent PCR amplification of blastocoel DNA - Giovana S Camargo; Cezinande Meira; Don R Bergfelt; José P. Oliveira-Filho; Cristiana R. Bromberger; Luiz D. Barros; Heloisa S Canesin; Giulia VR Lopes; Gabriel A Monteiro; Fernanda S Ignácio (Journal of Equine Veterinary Science, 2023)

Long term lithium availability and electric mobility: What can we learn from resource assessment? - Francesco Sanginesi; Giulia Millacci; Andrea Giaccherini; Antonella Buccianti; Lorenzo Fusi; Francesco Di Benedetto; Luca Pardi (Journal of Geochemical Exploration, 2023)

The leaching behaviors of lead, zinc, and sulfate in pyrite ash contaminated soil: mineralogical assessments and environmental implications - Yikai Liu; Simone Molinari; Maria Chiara Dalconi; Luca Valentini; Giulia Ricci; Claudio Carrer; Giorgio Ferrari; Gilberto Artioli (Journal of Environmental Chemical Engineering, 2023)

Sweet chestnut forests under black locust invasion threat and different management: An assessment of stand structure and biodiversity - Thomas Campagnaro; Giovanni Trentanovi; Simone Iacopino; Andrea Squartini; Flora Giulia Simonelli; Edoardo Alterio; Giovanni Bertoldo; Giuseppe Concheri; Stefano Grigolato; Alessia Portaccio; Andrea Rizzi; Roberto Rizzieri Masin; et al. (Forest Ecology and Management, 2023)

Arabic coffee infusion based kombucha: Characterization and biological activity during fermentation, and in vivo toxicity - Jeniffer Ferreira de Miranda; Giulia Martins Pereira Belo; Laís Silva de Lima; Kelly Alencar Silva; Thais Matsue Uekane; Alice Gonçalves Martins Gonzalez; Vanessa Naciuk Castelo Branco; Nayla Souza Pitangui; Fabrício Freitas Fernandes; Adriene Ribeiro Lima (Food Chemistry, 2023)

Untargeted lipidomic profiling of grapes highlights the importance of modified lipid species beyond the traditional compound classes - Mar Garcia-Aloy; Domenico Masuero; Giulia Chitarrini; Domen Škrab; Paolo Sivilotti; Graziano Guella; Urska Vrhovsek; Pietro Franceschi (Food Chemistry, 2023)

An innovative index to incorporate transcriptomic data into weight of evidence approaches for environmental risk assessment - Martina Cecchetto; Luca Peruzza; Elisa Giubilato; Ilaria Bernardini; Giulia Dalla Rovere; Antonio Marcomini; Francesco Regoli; Luca Bargelloni; Tomaso Patarnello; Elena Semenzin; Massimo Milan (Environmental Research, 2023)

Seismically-derived porosity of deep-sea sediments over the last 74 Ma in the equatorial Atlantic Ocean: Implications for paleo-climate - Giulia Matilde Ferrante; Satish C. Singh; Pranav Audhkhasi; Colin J. Thomson; Venkata Vaddineni; Milena Marjanović (Earth and Planetary Science Letters, 2023)

l-carvone decreases breast cancer cells adhesion, migration, and invasion by suppressing FAK activation - Lucas Trevisan França de Lima; Fernando Augusto de Oliveira Ganzella; Gabriela Casani Cardoso; Verônica dos Santos Pires; Andressa Chequin; Giulia Luiza Santos; Karin Braun-Prado; Claudia Martins Galindo; Odair Braz Junior; Marcelo Beltrão Molento; Alexandra Acco; Eliana Rezende Adami; et al. (Chemico-Biological Interactions, 2023)

Thermal comfort and adaptive capacities: Differences among students at various school stages - Giulia Torriani; Giulia Lamberti; Giacomo Salvadori; Fabio Fantozzi; Francesco Babich (Building and Environment, 2023)

Determining the filtration effectiveness of non-standard respiratory protective devices by an ad-hoc laboratory methodology - Mauro Scungio; Giulia Parlani (Atmospheric Environment, 2023)

First genetic detection and characterization of canine parvovirus type 2 (Carnivore protoparvovirus 1) in southwestern Ethiopia - Dechassa Tegegne; Girma Tsegaye; Giulia Faustini; Giovanni Franzo (Veterinary Research Communications, 2023)
The species Carnivore protoparvovirus 1 includes viruses, e.g. canine parvovirus (CPV-2) and feline panleukopenia virus (FPV), which are among the most relevant for pets, causing extremely severe clinical signs and high fatality rate in dogs and cats. Moreover, a broad range of wild hosts, including endangered ones, were proven to be susceptible. Currently, no data on CPV-2 molecular epidemiology and strain characterization are available in Ethiopia, also considering the frequent contacts between domestic and wild populations. In the present study, a molecular epidemiology survey was performed on 92 fecal samples collected from domestic ( n = 84) and stray ( n = 8) dogs in southwestern Ethiopia in 2021. Approximately, 10% of the samples tested positive and the complete VP2 sequences of 5 strains were obtained, classified within the CPV-2a ( n = 1) and CPV-2c ( n = 4) antigenic variants. In most instances, the closest genetic relatives were strains of Chinese origin, which is fully compatible with the intense relationships that have been developing between the two countries, involving human being travels and their pets as well. Considering the clinical relevance of this infection and the risk it poses to local domestic and wild carnivore populations, especially endangered ones, much stronger monitoring and surveillance activity on foreign incoming animals should be performed. More strict constraints on animal introduction, e.g. compulsory vaccination, should also be considered.

Feasibility of 16S rRNA sequencing for cerebrospinal fluid microbiome analysis in cattle with neurological disorders: a pilot study - Sara Ferrini; Elena Grego; Ugo Ala; Giulia Cagnotti; Flaminia Valentini; Giorgia Di Muro; Barbara Iulini; Maria Cristina Stella; Claudio Bellino; Antonio D’Angelo (Veterinary Research Communications, 2023)
Bacterial infection of the central nervous system (CNS) in cattle requires prompt and adequate antimicrobial treatment. The current gold standard for antemortem etiological diagnosis is cerebrospinal fluid (CSF) culture, which often yields false negative results. CSF has long been considered a sterile district in healthy patients, but this notion has been recently challenged. For this pilot study, we used 16S rRNA gene sequencing to investigate the microbial composition of CSF of cattle presenting with CNS disorders and to compare it between subjects with CNS infections and with CNS disorders of other nature. The study sample was 10 animals: 4 presenting with CNS infectious-inflammatory diseases and 6 with other CNS disorders, based on definitive diagnosis. Since the initial round of a standard 16S rRNA PCR did not yield sufficient genetic material for sequencing in any of the samples, the protocol was modified to increase its sensitivity. Bacterial genetic material was identified in 6 animals and 2 groups were formed: an infectious inflammatory (n = 3) and a noninfectious inflammatory group (n = 3). The most frequently expressed bacterial families were Pseudomonadaceae (44.61%), Moraxellaceae (19.54%), Mycobacteriaceae (11.80%); the genera were Pseudomonas (45.42%), Acinetobacter (19.91%), Mycobacterium (12.01%). There were no detectable differences in the CSF microbial composition of the samples from the two groups. Sequencing of bacterial DNA present in the CSF was possible only after increasing PCR sensitivity. The results of 16S rRNA sequencing showed the presence of a microbial community in the CSF in cattle with neurological disorders. Further studies, in which CSF samples from healthy animals and samples from the environment are included as controls, are needed.

Specialized metabolites from plants as a source of new multi-target antiviral drugs: a systematic review - Maria Ponticelli; Maria Laura Bellone; Valentina Parisi; Annamaria Iannuzzi; Alessandra Braca; Nunziatina de Tommasi; Daniela Russo; Annalisa Sileo; Paola Quaranta; Giulia Freer; Mauro Pistello; Luigi Milella (Phytochemistry Reviews, 2023)
Viral infections have always been the main global health challenge, as several potentially lethal viruses, including the hepatitis virus, herpes virus, and influenza virus, have affected human health for decades. Unfortunately, most licensed antiviral drugs are characterized by many adverse reactions and, in the long-term therapy, also develop viral resistance; for these reasons, researchers have focused their attention on investigating potential antiviral molecules from plants. Natural resources indeed offer a variety of specialized therapeutic metabolites that have been demonstrated to inhibit viral entry into the host cells and replication through the regulation of viral absorption, cell receptor binding, and competition for the activation of intracellular signaling pathways. Many active phytochemicals, including flavonoids, lignans, terpenoids, coumarins, saponins, alkaloids, etc., have been identified as potential candidates for preventing and treating viral infections. Using a systematic approach, this review summarises the knowledge obtained to date on the in vivo antiviral activity of specialized metabolites extracted from plant matrices by focusing on their mechanism of action.

CML-Cardio: a cascade machine learning model to predict cardiovascular disease risk as a primary prevention strategy - Bruno Alberto Soares Oliveira; Giulia Zanon Castro; Giovanna Luiza Medina Ferreira; Frederico Gadelha Guimarães (Medical & Biological Engineering & Computing, 2023)

Cerebrospinal Fluid CXCL13 as Candidate Biomarker of Intrathecal Immune Activation, IgG Synthesis and Neurocognitive Impairment in People with HIV - Mattia Trunfio; Lorenzo Mighetto; Laura Napoli; Cristiana Atzori; Marco Nigra; Giulia Guastamacchia; Stefano Bonora; Giovanni Di Perri; Andrea Calcagno (Journal of Neuroimmune Pharmacology, 2023)

Physical Activity in Oncology: To Do, Not to Do, and How to Do It? An Announcement of an Educational Program - Helena Biancuzzi; Francesca Dal Mas; Giulia Bongiorno; Rym Bednarova; Luca Miceli (Journal of Cancer Education, 2023)

Pulse, Shunt and Storage: Hydrological Contraction Shapes Processing and Export of Particulate Organic Matter in River Networks - Núria Catalàn; Rubén del Campo; Lauren Talluto; Clara Mendoza-Lera; Giulia Grandi; Susana Bernal; Daniel von Schiller; Gabriel Singer; Enrico Bertuzzo (Ecosystems, 2023)
Streams and rivers act as landscape-scale bioreactors processing large quantities of terrestrial particulate organic matter (POM). This function is linked to their flow regime, which governs residence times, shapes organic matter reactivity and controls the amount of carbon (C) exported to the atmosphere and coastal oceans. Climate change impacts flow regimes by increasing both flash floods and droughts. Here, we used a modelling approach to explore the consequences of lateral hydrological contraction, that is, the reduction of the wet portion of the streambed, for POM decomposition and transport at the river network scale. Our model integrates seasonal leaf litter input as generator of POM, transient storage of POM on wet and dry streambed portions with associated decomposition and ensuing changes in reactivity, and transport dynamics through a dendritic river network. Simulations showed that the amount of POM exported from the river network and its average reactivity increased with lateral hydrological contraction, due to the combination of (1) low processing of POM while stored on dry streambeds, and (2) large shunting during flashy events. The sensitivity analysis further supported that high lateral hydrological contraction leads to higher export of higher reactivity POM, regardless of transport coefficient values, average reactivity of fresh leaf litter and differences between POM reactivity under wet and dry conditions. Our study incorporates storage in dry streambed areas into the pulse-shunt concept (Raymond and others in Ecology 97(1):5–16, 2016. https://doi.org/10.1890/14-1684.1 ), providing a mechanistic framework and testable predictions about leaf litter storage, transport and decomposition in fluvial networks.

Cardiovascular Harmful Effects of Recommended Daily Doses (13 µg/kg/day), Tolerable Upper Intake Doses (0.14 mg/kg/day) and Twice the Tolerable Doses (0.28 mg/kg/day) of Copper - Filipe Martinuzo Filetti; Ingridy Reinholz Grafites Schereider; Giulia Alessandra Wiggers; Marta Miguel; Dalton Valentim Vassallo; Maylla Ronacher Simões (Cardiovascular Toxicology, 2023)

Weber Syndrome - Marina Romozzi; Giulia Bramato; Marco Luigetti (Acta Neurologica Belgica, 2023)

Circular economy and sustainability in the tourism industry: critical analysis of integrated solutions and good practices in European and Chinese case studies - Kan Li; Giulia Cipolletta; Corinne Andreola; Anna Laura Eusebi; Barbara Kulaga; Silvio Cardinali; Francesco Fatone (Environment, Development and Sustainability, 2023)

Standards of Fluid Biomarker Collection and Pre-analytical Processes in Humans and Mice: Recommendations by the Ataxia Global Initiative Working Group on Biomarkers - Filippo M. Santorelli; Hayley S. McLoughlin; Justin M. Wolter; Daniele Galatolo; Matthis Synofzik; David Mengel; Puneet Opal; Antonijevic Irina; Auburger Georg; Bataller Luis; Bertini Enrico; Boesch Sylvia; et al. (The Cerebellum, 2023)

Biochemical composition and reproductive cycle of the clam Chamelea gallina in the Northern Adriatic Sea: an after-10-year comparison of patterns and changes - Vanessa Moschino; Giulia Rizzo; Tihana Marĉeta; Federica Cernigai; Luciano Masiero; Luisa Da Ros; Maria Gabriella Marin (Frontiers in Marine Science, 2023)
The study of the relationships between growth patterns, energy reserves and reproduction, and their interdependency with environmental variables is crucial to increase the knowledge of the physiological processes regulating the recruitment and survival of commercially exploited bivalve species. In the present study, the biochemical profile and gametogenic cycle of the striped Venus clam Chamelea gallina monthly sampled in fishing grounds of the Chioggia district in 2001 and 2010 were investigated to identify possible variations that occurred after 10 years and to analyze inter-relationships among the biological parameters with changing environmental conditions. Our results indicated that higher phytoplankton availability and increased water temperature recorded from 2001 to 2010 resulted in higher reserve accumulation, mostly in the form of proteins, carbohydrates and glycogen. An increase was also observed in the calcification rate of the shells, which consequently became heavier in clams collected in 2010. Moreover, in 2010, as for the reproductive conditions, a prolonged spawning period was observed with respect to 2002. Overall results highlighted clear-cut differences in the physiological performances of clams collected in 2001 and 2010, suggesting the importance to monitor changes over time to unveil potential pros and cons for single populations of commercial interest.

A standardised ecosystem services framework for the deep sea - Giulia La Bianca; Sian Rees; Martin J. Attrill; Amanda T. Lombard; Kirsty A. McQuaid; Holly J. Niner; Henk van Rein; Kerry J. Sink; Kerry L. Howell (Frontiers in Marine Science, 2023)
Despite its remoteness, human activity has impacted the deep sea and changes to the structure and function of deep-sea ecosystems are already noticeable. In terrestrial and shallow water marine environments, demonstrating how ecosystems support human well-being has been instrumental in setting policy and management objectives for sustainable resource use. Foundational to this approach is a framework of ecosystem service (ES) classification and a synthesis of the knowledge base, which can then be used to structure decision-support tools such as ecosystem accounts or Environmental Impact Assessments. At present, no such framework exists for the deep sea. There is thus an urgent need to determine and assess the ES provided by deep-sea habitats and species before (potentially irreversible) decisions are made about deep-sea habitat use and governance. As a first step towards the incorporation of ES in such decision-making, we undertake two systematic reviews of the scientific literature based on the principles of the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) systematic process. This was to define a comparative ES framework and synthesise the current evidence base for how deep-sea habitats support ecosystem services. Our framework proposes four supporting services, three regulating services, four provisioning services and three cultural services for which there is an established and growing body of evidence for the role of deep-sea habitats. The ES framework presented here provides a structure for deep-sea ecosystem services. In its next phase of development, this could provide the foundation for the development of habitat-ecosystem service matrices, which are a critical component for truly accounting for ES in decision-making, particularly spatial management. This framework has significant implications for deep-sea management, conservation and policy, as it provides an ecosystem services-based tool that can be used in any deep-sea ecosystems management across the planet, and it also shows how critical these data gaps are for today’s decisions and how seriously they should be considered in decision-making processes.

Quantifying Transgressive Coastal Changes Using UAVs: Dune Migration, Overwash Recovery, and Barrier Flooding Assessment and Interferences with Human and Natural Assets - Giulia Casagrande; Annelore Bezzi; Saverio Fracaros; Davide Martinucci; Simone Pillon; Paolo Salvador; Stefano Sponza; Giorgio Fontolan (Journal of Marine Science and Engineering, 2023)
The advantages derived from the use of Uncrewed Aerial Vehicles (UAVs) are well-established: they are cost-effective and easy to use. There are numerous environmental applications, particularly when monitoring contexts characterized by rapid morphological changes and high rates of sediment transport, such as coastal areas. In this paper, three different case studies of survey and monitoring with high resolution and accuracy obtained through the use of UAVs are presented; these concern transgressive coastal sites. Results allow for the definition and quantification of coastal landforms and processes, including: (i) The anatomy of a parabolic dune and the rate of landward migration that could interfere with a tourist settlement; (ii) The mode and timing of morphological recovery and realignment of a barrier island overwashed by storm surge episodes; and (iii) The potential flood risk of a progradational spit that is a nesting site of a species of migratory breeding birds of conservation concern. The results demonstrate and confirm that, through a good coupling of drone-sensed quality data and accurate topographic control, quantitative estimates that are useful in assessing the impacts of natural processes involving both human and natural assets can be obtained.

Changes in brain rhythms and connectivity tracking fear acquisition and reversal - Gabriele Pirazzini; Francesca Starita; Giulia Ricci; Sara Garofalo; Giuseppe di Pellegrino; Elisa Magosso; Mauro Ursino (Brain Structure and Function, 2023)
Fear conditioning is used to investigate the neural bases of threat and anxiety, and to understand their flexible modifications when the environment changes. This study aims to examine the temporal evolution of brain rhythms using electroencephalographic signals recorded in healthy volunteers during a protocol of Pavlovian fear conditioning and reversal. Power changes and Granger connectivity in theta, alpha, and gamma bands are investigated from neuroelectrical activity reconstructed on the cortex. Results show a significant increase in theta power in the left (contralateral to electrical shock) portion of the midcingulate cortex during fear acquisition, and a significant decrease in alpha power in a broad network over the left posterior-frontal and parietal cortex. These changes occur since the initial trials for theta power, but require more trials (3/4) to develop for alpha, and are also present during reversal, despite being less pronounced. In both bands, relevant changes in connectivity are mainly evident in the last block of reversal, just when power differences attenuate. No significant changes in the gamma band were detected. We conclude that the increased theta rhythm in the cingulate cortex subserves fear acquisition and is transmitted to other cortical regions via increased functional connectivity allowing a fast theta synchronization, whereas the decrease in alpha power can represent a partial activation of motor and somatosensory areas contralateral to the shock side in the presence of a dangerous stimulus. In addition, connectivity changes at the end of reversal may reflect long-term alterations in synapses necessary to reverse the previously acquired contingencies.

Early-life exposure to environmentally relevant concentrations of triclocarban impairs ocular development in zebrafish larvae - Giulia Caioni; Carmine Merola; Cristiano Bertolucci; Tyrone Lucon-Xiccato; Beste Başak Savaşçı; Mara Massimi; Martina Colasante; Giulia Fioravanti; Nunzio Antonio Cacciola; Rodolfo Ippoliti; Michele d’Angelo; Monia Perugini; et al. (Chemosphere, 2023)

Micro-scale UHI risk assessment on the heat-health nexus within cities by looking at socio-economic factors and built environment characteristics: The Turin case study (Italy) - Marta Ellena; Giulia Melis; Nicolás Zengarini; Eduardo Di Gangi; Guglielmo Ricciardi; Paola Mercogliano; Giuseppe Costa (Urban Climate, 2023)

Processes involved in biochemical response to pesticides by lizard Podarcis siculus (Rafinesque-Schmaltz, 1810) – A field study - Ginevra Moltedo; Barbara Catalano; Giacomo Martuccio; Giulio Sesta; Giulia Romanelli; Anna Lauria; Maria Teresa Berducci; Roberta Parravano; Chiara Maggi; Giulia Simbula; Leonardo Vignoli; Fulvio Onorati; et al. (Toxicology and Applied Pharmacology, 2023)

The environmental impact of permanent meadows-based farms: A comparison among different dairy farm management systems of an Italian cheese - Giulia Rencricca; Federico Froldi; Maurizio Moschini; Marco Trevisan; Sami Ghnimi; Lucrezia Lamastra (Sustainable Production and Consumption, 2023)

Assessment of passive and active buildings resilience to gas supply disruption in winter across European climates - Delia D'Agostino; Cristina Becchio; Giulia Crespi; Stefano Paolo Corgnati (Sustainable Cities and Society, 2023)

Forest ecology and fire history of the mixed conifer forest belt in the Italian Alps from Late Roman fires to the 20th century under cultural and climate pressure - Giulia Furlanetto; Davide Abu El Khair; Federica Badino; Paolo Bertuletti; Roberto Comolli; Valter Maggi; Renata Perego; Cesare Ravazzi (Review of Palaeobotany and Palynology, 2023)

Maternal treatment with pegbovigrastim influences growth performance and immune-metabolic status of calves during the pre-weaning period - Vincenzo Lopreiato; Andrea Minuti; Erminio Trevisi; Giuseppe Piccione; Giulia Ferronato; Juan J. Loor; Domenico Britti; Luigi Liotta; Claudia Giannetto; Francesca Arfuso (Research in Veterinary Science, 2023)

Reflection, emission, and polarization properties of surfaces made of hyperfine grains, and implications for the nature of primitive small bodies - Robin Sultana; Olivier Poch; Pierre Beck; Bernard Schmitt; Eric Quirico; Stefano Spadaccia; Lucas Patty; Antoine Pommerol; Alessandro Maturilli; Jörn Helbert; Giulia Alemanno (Icarus, 2023)

Solar forcing for nutricline depth variability inferred by coccoliths in the pre-industrial northwestern Mediterranean - Alessandro Incarbona; Sergio Bonomo; Isabel Cacho; Fabrizio Lirer; Giulia Margaritelli; Delia Pecoraro; Patrizia Ziveri (Global and Planetary Change, 2023)

Occurrence and migration study of chemicals from baking paper and aluminium foil - Elisa Sonego; Patrizia Di Filippo; Carmela Riccardi; Donatella Pomata; Angela Bannò; Giulia Simonetti; Francesca Buiarelli (Food Chemistry, 2023)

Revealing adulterated olive oils by triacylglycerol screening methods: Beyond the official method - Berta Torres-Cobos; Beatriz Quintanilla-Casas; Giulia Vicario; Francesc Guardiola; Alba Tres; Stefania Vichi (Food Chemistry, 2023)

Fish Erythrocyte Extracellular Traps (FEETs) are an evolutionarily conserved cellular process triggered by different stimuli - Giulia Rinaldi; Neila Álvarez de Haro; Anuruddika J. Fernando; Andrew P. Desbois; Calum T. Robb; Adriano G. Rossi (Fish & Shellfish Immunology, 2023)

Assessment of silicone wristbands for monitoring personal exposure to chlorinated paraffins (C8-36): A pilot study - Shanshan Yin; Thomas J. McGrath; Adam Cseresznye; Jasper Bombeke; Giulia Poma; Adrian Covaci (Environmental Research, 2023)

Relationship of long-term air pollution exposure with asthma and rhinitis in Italy: an innovative multipollutant approach - Sara Maio; Salvatore Fasola; Alessandro Marcon; Anna Angino; Sandra Baldacci; Maria Beatrice Bilò; Roberto Bono; Stefania La Grutta; Pierpaolo Marchetti; Giuseppe Sarno; Giulia Squillacioti; Ilaria Stanisci; et al. (Environmental Research, 2023)

Hazard and health risk assessment of exposure to pharmaceutical active compounds via toxicological evaluation by zebrafish - Imen Ben Chabchoubi; Su Shiung Lam; Stacey Ellen Pane; Mohamed Ksibi; Giulia Guerriero; Olfa Hentati (Environmental Pollution, 2023)

Not only wide range shifts: Marine warming and heat waves influence spatial traits of a mediterranean common bottlenose dolphin population - Gabriella La Manna; Fabio Ronchetti; Francesco Perretti; Giulia Ceccherelli (Estuarine, Coastal and Shelf Science, 2023)

Correction to: Adolescent self‑administration of the synthetic cannabinoid receptor agonist JWH‑018 induces neurobiological and behavioral alterations in adult male mice - Giulia Margiani; Maria Paola Castelli; Nicholas Pintori; Roberto Frau; Maria Grazia Ennas; Antonio C. Pagano Zottola; Valeria Orrù; Valentina Serra; Edoardo Fiorillo; Paola Fadda; Giovanni Marsicano; Maria Antonietta De Luca (Psychopharmacology, 2023)

Immortalized Alzheimer’s Disease Astrocytes: Characterization of Their Proteolytic Systems - Chunmei Gong; Laura Bonfili; Yadong Zheng; Valentina Cecarini; Massimiliano Cuccioloni; Mauro Angeletti; Giulia Dematteis; Laura Tapella; Armando A. Genazzani; Dmitry Lim; Anna Maria Eleuteri (Molecular Neurobiology, 2023)
Alzheimer’s disease (AD) is a progressive neurodegeneration with dysfunctions in both the ubiquitin–proteasome system (UPS) and autophagy. Astroglia participation in AD is an attractive topic of research, but molecular patterns are partially defined and available in vitro models have technical limitations. Immortalized astrocytes from the hippocampus of 3xTg-AD and wild-type mice (3Tg-iAstro and WT-iAstro, respectively) have been obtained as an attempt to overcome primary cell line limitations and this study aims at characterizing their proteolytic systems, focusing on UPS and autophagy. Both 26S and 20S proteasomal activities were downregulated in 3Tg-iAstro, in which a shift in catalytic subunits from constitutive 20S proteasome to immunoproteasome occurred, with consequences on immune functions. In fact, immunoproteasome is the specific complex in charge of clearing damaged proteins under inflammatory conditions. Parallelly, augmented expression and activity of the lysosomal cathepsin B, enhanced levels of lysosomal-associated membrane protein 1, beclin1, and LC3-II, together with an increased uptake of monodansylcadaverine in autophagic vacuoles, suggested autophagy activation in 3Tg-iAstro. The two proteolytic pathways were linked by p62 that accumulated in 3Tg-iAstro due to both increased synthesis and decreased degradation in the UPS defective astrocytes. Treatment with 4-phenylbutyric acid, a neuroprotective small chemical chaperone, partially restored proteasome and autophagy-mediated proteolysis in 3Tg-iAstro. Our data shed light on the impaired proteostasis in 3Tg-iAstro with proteasome inhibition and autophagic compensatory activation, providing additional validation of this AD in vitro model, and propose a new mechanism of action of 4-phenylbutyric acid in neurodegenerative disorders.

Crossing borders, building new ones, or shifting boundaries? Shared narratives and individual paths towards inter/transdisciplinarity in research centres for urban sustainability - Laura Soledad Norton; Giulia Sonetti; Mauro Sarrica (Sustainability Science, 2023)
Inter/transdisciplinarity (ITD) is a pillar of sustainability studies, often presented as the way to conduct research and practice especially in conflictual and politicised real-world stakeholder constellations. Several studies emphasise the need to consider the communicative processes through which it is put into practice. However, there is still a dearth of research that explores the meanings key actors associate with ITD and how they account for the material, practical and communicative facets of their everyday experience. This work seeks to collect the voice of leaders of inter/transdisciplinary research centres, identify shared repertoires used to interpret their experience in the field, and reflect on how shared narratives could inspire or impede researchers engaged in ITD. A discursive analysis was applied to 23 semi-structured interviews conducted with leaders of research centres on urban sustainability. Results identified diverse interpretative repertoires used to define ITD and to interpret the barriers that, in the eyes of these key actors, have to be crossed to become ITD researchers. These elements are combined into three main narratives used by participants to position themselves and the researchers involved in ITD. Despite being functional to self-representation, these shared narratives contribute towards depicting ITD as an individual escape, and interdisciplinary research centres as sanctuaries of a sort, thus paradoxically preserving the status quo. A third narrative advocates structural shifts and is coherent with the need for deeper changes and persistent recognition of ITD in sustainability studies.

Predator-prey traits and foraging habitat shape the diet of a common insectivorous bat - Leonardo Ancillotto; Angelica Falanga; Giulia Agostinetto; Nicola Tommasi; Antonio P. Garonna; Flavia de Benedetta; Umberto Bernardo; Andrea Galimberti; Paola Conti; Danilo Russo (Acta Oecologica, 2023)

Recent genetic exchanges and admixture shape the genome and population structure of the zoonotic pathogen Cryptosporidium parvum - Giulia I. Corsi; Swapnil Tichkule; Anna Rosa Sannella; Paolo Vatta; Francesco Asnicar; Nicola Segata; Aaron R. Jex; Cock van Oosterhout; Simone M. Cacciò (Molecular Ecology, 2023)
Cryptosporidium parvum is a globally distributed zoonotic pathogen and a major cause of diarrhoeal disease in humans and ruminants. The parasite's life cycle comprises an obligatory sexual phase, during which genetic exchanges can occur between previously isolated lineages. Here, we compare 32 whole genome sequences from human‐ and ruminant‐derived parasite isolates collected across Europe, Egypt and China. We identify three strongly supported clusters that comprise a mix of isolates from different host species, geographic origins, and subtypes. We show that: (1) recombination occurs between ruminant isolates into human isolates; (2) these recombinant regions can be passed on to other human subtypes through gene flow and population admixture; (3) there have been multiple genetic exchanges, and most are probably recent; (4) putative virulence genes are significantly enriched within these genetic exchanges, and (5) this results in an increase in their nucleotide diversity. We carefully dissect the phylogenetic sequence of two genetic exchanges, illustrating the long‐term evolutionary consequences of these events. Our results suggest that increased globalization and close human‐animal contacts increase the opportunity for genetic exchanges between previously isolated parasite lineages, resulting in spillover and spillback events. We discuss how this can provide a novel substrate for natural selection at genes involved in host–parasite interactions, thereby potentially altering the dynamic coevolutionary equilibrium in the Red Queens arms race.

Quantitative Oculomotor Assessment in Hereditary Ataxia: Systematic Review and Consensus by the Ataxia Global Initiative Working Group on Digital-motor Biomarkers - Pilar Garces; Chrystalina A. Antoniades; Anna Sobanska; Norbert Kovacs; Sarah H. Ying; Anoopum S. Gupta; Susan Perlman; David J. Szmulewicz; Chiara Pane; Andrea H. Németh; Laura B. Jardim; Giulia Coarelli; et al. (The Cerebellum, 2023)
Oculomotor deficits are common in hereditary ataxia, but disproportionally neglected in clinical ataxia scales and as outcome measures for interventional trials. Quantitative assessment of oculomotor function has become increasingly available and thus applicable in multicenter trials and offers the opportunity to capture severity and progression of oculomotor impairment in a sensitive and reliable manner. In this consensus paper of the Ataxia Global Initiative Working Group On Digital Oculomotor Biomarkers, based on a systematic literature review, we propose harmonized methodology and measurement parameters for the quantitative assessment of oculomotor function in natural-history studies and clinical trials in hereditary ataxia. MEDLINE was searched for articles reporting on oculomotor/vestibular properties in ataxia patients and a study-tailored quality-assessment was performed. One-hundred-and-seventeen articles reporting on subjects with genetically confirmed ( n =1134) or suspected hereditary ataxia ( n =198), and degenerative ataxias with sporadic presentation ( n =480) were included and subject to data extraction. Based on robust discrimination from controls, correlation with disease-severity, sensitivity to change, and feasibility in international multicenter settings as prerequisite for clinical trials, we prioritize a core-set of five eye-movement types: (i) pursuit eye movements, (ii) saccadic eye movements, (iii) fixation, (iv) eccentric gaze holding, and (v) rotational vestibulo-ocular reflex. We provide detailed guidelines for their acquisition, and recommendations on the quantitative parameters to extract. Limitations include low study quality, heterogeneity in patient populations, and lack of longitudinal studies. Standardization of quantitative oculomotor assessments will facilitate their implementation, interpretation, and validation in clinical trials, and ultimately advance our understanding of the evolution of oculomotor network dysfunction in hereditary ataxias.

Experimental thermocline deepening highlights the resilience of the seagrass Posidonia oceanica: An opportunity to investigate shoot adaptability - Patrizia Stipcich; Vasilis Resaikos; Giulia Ceccherelli (Marine Pollution Bulletin, 2023)

Supplemental red LED light promotes plant productivity, “photomodulates” fruit quality and increases Botrytis cinerea tolerance in strawberry - Giulia Lauria; Ermes Lo Piccolo; Costanza Ceccanti; Lucia Guidi; Rodolfo Bernardi; Fabrizio Araniti; Lorenzo Cotrozzi; Elisa Pellegrini; Michela Moriconi; Tommaso Giordani; Claudio Pugliesi; Cristina Nali; et al. (Postharvest Biology and Technology, 2023)

A methodology for risk assessment of LNG carriers accessing vulnerable port areas - Giulia Marroni; Valeria Casson Moreno; Federica Ovidi; Tommaso Chiavistelli; Gabriele Landucci (Ocean Engineering, 2023)

Field development of Posidonia oceanica seedlings changes under predicted acidification conditions - Arianna Pansini; Pedro Beca-Carretero; Manuel Berlino; Gianluca Sarà; Dagmar B. Stengel; Patrizia Stipcich; Giulia Ceccherelli (Marine Environmental Research, 2023)

Characterisation of the correlations between oxidative potential and in vitro biological effects of PM10 at three sites in the central Mediterranean - Maria Rachele Guascito; Maria Giulia Lionetto; Franco Mazzotta; Marianna Conte; Maria Elena Giordano; Roberto Caricato; Anna Rita De Bartolomeo; Adelaide Dinoi; Daniela Cesari; Eva Merico; Laura Mazzotta; Daniele Contini (Journal of Hazardous Materials, 2023)

A methodological approach to estimate the overall heat transfer coefficient in olive paste malaxers - Ferdinando Corti; Bruno Zanoni; Alessandro Parenti; Piernicola Masella; Carlotta Breschi; Giulia Angeloni; Agnese Spadi; Lorenzo Guerrini (Journal of Food Engineering, 2023)

A stepwise regression to identify relevant variables affecting the environmental impacts of clinker production - Giulia Del Serrone; Laura Moretti (Journal of Cleaner Production, 2023)

Effects of different gasification biochar grain size on greenhouse gases and ammonia emissions in municipal aerated composting processes - Filippo Ottani; Massimiliano Parenti; Giulia Santunione; Giuseppe Moscatelli; Rocky Kahn; Simone Pedrazzi; Giulio Allesina (Journal of Environmental Management, 2023)

Large-scale grid-based detection in occupancy surveys of a threatened small mammal: A comparison of two non-invasive methods - Alexandra Oliveira; Denis Medinas; João Craveiro; Catarina Milhinhas; Helena Sabino-Marques; Tiago Mendes; Giulia Spadoni; André Oliveira; Luís Guilherme Sousa; Joaquim T. Tapisso; Sara Santos; Margarida Lopes-Fernandes; et al. (Journal for Nature Conservation, 2023)

First Confirmed Record of the Smalltooth Sand Tiger, Odontapis Ferox, in Galicia (NW Spain) - Gonzalo Mucientes; Nair Vilas-Arrondo; Giulia Secci-Petretto; Uxía Vázquez; Xabier Pin; Alfredo López; L. Filipe C. Castro; Elsa Froufe (Thalassas: An International Journal of Marine Sciences, 2023)
The smalltooth sand tiger shark Odontaspis ferox (Risso, 1810) appears to have an extensive and fragmented distribution in tropical and warm-temperate worldwide oceans. One female of O. ferox was caught and released by a small-scale fishery vessel in Ría de Arousa (Northwest of Spain), subsequently stranded still alive on the coast (42°33’18.4"N 8°49’18.3"O) after a few hours. The individual (336 cm total length, weight ~ 300 kg) was identified based on a collection of features including the characteristic dentition, body morphology and by molecular assignment. This is the first confirmed record of O. ferox in Galician waters. This finding complements the knowledge of the geographic distribution and occurrence of this rare and sparse species in the Northeastern Atlantic.

Growth rates and age at maturity of Mediterranean loggerhead sea turtles estimated from a single-population foraging ground - Giulia Baldi; Giovanni Furii; Massimo Del Vecchio; Pasquale Salvemini; Carola Vallini; Valeria Angelini; Sauro Pari; Kamyla Lombardi Moraes; Dimitris Margaritoulis; Anxhela Çurri; Bojan Lazar; Paolo Casale (Marine Biology, 2023)
In sea turtles, somatic growth rates and Age at Sexual Maturity (ASM) are important parameters for investigating population dynamics. Moreover, ASM informs on the time lag needed to observe the effects of past environmental variables, threats and conservation measures acting at nesting beaches on future numbers of clutches or nesting females, that are the most monitored indices. Assessing ASM of mixed populations that share the same foraging areas is difficult, as in the case of the Mediterranean Sea that is frequented by turtles originating from both the Mediterranean and the Atlantic. Here we investigated growth rates of loggerhead sea turtles ( Caretta caretta ) foraging in the Adriatic Sea, known to be frequented only by individuals of Mediterranean origin. Capture–mark–recapture records of 79 turtles provided growth rates ranging from – 1.1 to 9.6 cm yr −1 which were analyzed through Generalized Additive Models. When integrated with previous data on growth rates in the first years of life, results indicate a non-monotonic growth curve, likely due to an ontogenetic shift from oceanic to neritic areas. Using an integration equation, we estimated mean ASM to be 29.5 or 25.0 year based on mean nester size in Greece (83.4 cm curved carapace length, CCL) or across the Mediterranean (79.7 cm CCL), respectively. Growth rates and size-at-age are similar to the Atlantic population, but Mediterranean turtles mature earlier at a smaller size. The heterogenous growth rates and ASM reported so far in the Mediterranean are probably due, at least in part, to different foraging areas.

Occupational exposure to arsenic, mercury and UV radiation and risk of melanoma: a case–control study from Italy - Giulia Collatuzzo; Paolo Boffetta; Emi Dika; Giovanni Visci; Carlotta Zunarelli; Simona Mastroeni; Gianluca Antonelli; Cristina Fortes (International Archives of Occupational and Environmental Health, 2023)

Age-associated changes in circulatory fatty acids: new insights on adults and long-lived individuals - Sawan Ali; Anna Aiello; Tiziana Zotti; Giulia Accardi; Gaetano Cardinale; Pasquale Vito; Anna Calabrò; Mattia Emanuela Ligotti; Mariano Intrieri; Graziamaria Corbi; Calogero Caruso; Giuseppina Candore; et al. (GeroScience, 2023)

Detection of human neurotropic JCPyV DNA sequence in pediatric anaplastic xanthoastrocytoma - Sara Passerini; Carla Prezioso; Annalisa Prota; Giulia Babini; Lavinia Bargiacchi; Daniela Bartolini; Ugo Moens; Manila Antonelli; Valeria Pietropaolo (Journal of NeuroVirology, 2023)
Due to its peculiar histopathological findings, pleomorphic xanthoastrocytoma (PXA), a rare cerebral tumor of young adults with a slow growth and a good prognosis, resembles to the lytic phase of progressive multifocal leukoencephalopathy, a fatal neurodegenerative disease caused by JC polyomavirus (JCPyV). Therefore, the presence of JCPyV DNA was examined in an 11-year-old child with xanthoastrocytoma, WHO grade 3, by quantitative PCR (qPCR) and nested PCR (nPCR) using primers amplifying sequences encoding the N- and C-terminal region of large T antigen (LTAg), the non-coding control region (NCCR), and viral protein 1 (VP1) DNA. The expression of transcripts from LTAg and VP1 genes was also evaluated. In addition, viral microRNAs’ (miRNAs) expression was investigated. Cellular p53 was also searched at both DNA and RNA level. qPCR revealed the presence of JCPyV DNA with a mean value of 6.0 × 10 4 gEq/mL. nPCR gave a positive result for the 5ʹ region of the LTAg gene and the NCCR, whereas 3ʹ end LTAg and VP1 DNA sequences were not amplifiable. Only LTAg transcripts of 5ʹ end were found whereas VP1 gene transcript was undetectable. Although in most cases, either Mad-1 or Mad-4 NCCRs have been identified in association with JCPyV-positive human brain neoplasms, the archetype NCCR structure was observed in the patient’s sample. Neither viral miRNA miR-J1-5p nor p53 DNA and RNA were detected. Although the expression of LTAg supports the possible role of JCPyV in PXA, further studies are warranted to better understand whether the genesis of xanthoastrocytoma could depend on the transformation capacity of LTAg by Rb sequestration.

CDH1 mutations recurrence and global clustering in genetically tested families with hereditary diffuse gastric cancer syndrome: results from a systematic study - Giovanni Corso; Valentina Tagliaferri; Giulia Massari; Antonio Cioffi; Elisabetta Maria Cristina Rossi; Paolo Veronesi; Francesca Magnoni (Familial Cancer, 2023)

Metals and organic species associated with fine and coarse aerosol particles in an electronic waste recycling plant - Giulia Pazzi; Francesca Buiarelli; Patrizia Di Filippo; Donatella Pomata; Carmela Riccardi; Franco Lucarelli; Fabio Giardi; Elisa Sonego; Roberta Galarini; Stefano Lorenzetti; Laura Goracci; Giulia Simonetti (Air Quality, Atmosphere & Health, 2023)

Spatial genetic differentiation correlates with species assemblage turnover across tropical reef fish lineages - Maurine Vilcot; Camille Albouy; Giulia Francesca Azzurra Donati; Thomas Claverie; Pagu Julius; Stéphanie Manel; Loïc Pellissier; Fabien Leprieur (Global Ecology and Biogeography, 2023)
Aim Evaluating the similarity of diversity patterns across micro‐ to macroevolutionary scales in natural communities, such as species–genetic diversity correlations (SGDCs), may inform on processes shaping community assembly. However, whether SGDCs not only hold across communities but also across lineages has never been explored so far. Here we investigated SGDCs across co‐distributed taxa for different spatial components (α, β, γ), and formally tested the influence of dispersal traits on β‐SGDCs. Location Western Indian Ocean. Time period 2016–2017. Major taxa studied Tropical reef fish species with contrasting dispersal traits. Methods Using double‐digest restriction‐site associated DNA sequencing (ddRADseq) Single Nucleotide Polymorphism data for 20 tropical reef fishes and distribution data of 2,446 species belonging to 12 families, we analysed the correlations between within‐species genetic diversity and within‐family species diversity (i.e., lineage diversity) for the three spatial components (α, β, γ‐SGDCs). We then related the strength of β‐SGDCs per species to proxies of larval dispersal abilities. Results We detected positive and significant lineage‐based SGDC only for the β component, that is, the families showing the greatest level of species turnover among sites contain the species with the greatest levels of genetic differentiation. We showed that the Monsoon Drift mainly explained the β‐diversity patterns at both intraspecific and interspecific levels. Higher β‐SGDCs were found for species with short pelagic larval duration and weak larval swimming capacity. Main conclusions Our study reveals a strong correlation between genetic and species β‐diversity, a result explained by the presence of a ‘soft’ barrier and mediated by larval dispersal processes. This suggests that vicariance and dispersal limitation are major processes shaping β‐diversity patterns from microevolutionary to macroevolutionary scales in tropical reef fishes.

Anti- Trichomonas vaginalis activity of essential oils extracted from Caatinga Myrtaceae species and chemical composition of Eugenia pohliana DC. - Saulo Almeida de Menezes; Giulia Bongiorni Galego; Graziela de Vargas Rigo; Júlio César Ribeiro de Oliveira Farias de Aguiar; Bruno de Oliveira Veras; Lilian Cortez Sombra Vandesmet; Cícero Ramon Bezerra dos Santos; Mariana Gomes Vidal Sampaio; Clécia de Carvalho Marques; Vilmar Luiz Lermen; Daniela Maria do Amaral Ferraz Navarro; Márcia Vanusa da Silva; et al. (Natural Product Research, 2023)

Green Composites for Maritime Engineering: A Review - Vincenzo Crupi; Gabriella Epasto; Francesco Napolitano; Giulia Palomba; Ilaria Papa; Pietro Russo (Journal of Marine Science and Engineering, 2023)
Green composites have gained increasing attention in recent years as a sustainable alternative to traditional materials used in marine structures. These composites are made from biodegradable and renewable materials, making them environmentally friendly and reducing the subsequent carbon footprint. This review aims to provide a comprehensive overview of green composites materials and their applications in marine structures. This review includes a classification of the potential fibres and matrixes for green composites which are suitable for marine applications. The properties of green composites, such as their strength and Young’s modulus, are analysed and compared with those of traditional composites. An overview concerning current rules and regulations is presented. The applications of green composites in marine structures are reviewed, focusing on both shipbuilding and offshore applications. The main challenges in a wider application of green composites are also highlighted, as well as the benefits and future challenges.

Occurrence and congener profiles of dioxins (PCDDs), furans (PCDFs) and polychlorinated biphenyls (PCBs) in ovine and caprine milk samples collected in a very polluted site in Central Italy - Federica Castellani; Federico Marini; Giulia Simonetti; Carmela Protano; Leila Fabiani; Lamberto Manzoli; Matteo Vitali (Food Additives & Contaminants: Part A, 2023)

Mitigating effects on target and by-catch species fished by drifting longlines using circle hooks in the South Adriatic Sea (Central Mediterranean) - Pierluigi Carbonara; Giulia Prato; Simone Niedermüller; Sébastien Alfonso; Cosmidano Neglia; Marilena Donnaloia; Giuseppe Lembo; Maria Teresa Spedicato (Frontiers in Marine Science, 2023)
Introduction Longline fishing gear has a higher by-catch rate than any other type of commercial fishing gear. Nowadays, there is an urgent need to find efficient management strategies to mitigate by-catch and the use of new hook types could be one of them. This study investigates the effects of a longline fishery (which targets swordfish, Xiphias gladius , in the South Adriatic Sea) replacing the traditional J-type hook with a circle hook (C-type hook) on target and by-catch species. Methods For this purpose, a fishing trip of nine days – with seven fishing sets – was monitored. For both targeted swordfish and by-catch specimens caught (i.e., blue shark, Prionace glauca ; pelagic stingray, Pteroplatytrygon violacea; and loggerhead turtle, Caretta caretta ), data about the hook type used (J-type vs. C-type), the specimen size, and their capture condition were collected. Results and discussion With all species, we observed no significant difference in catch-per-unit-effort (CPUE) or specimen lengths between the two hook types. In addition, the hook type did not significantly affect the capture condition of swordfish, pelagic stingray, or loggerhead turtle specimens; however, it significantly affected the capture condition of blue sharks. The percentage of blue shark specimens found in healthy condition was higher when using a C-type hook (71.5%) than when using a J-type hook (22.6%). Overall, these preliminary results suggest that the use of a C-type hook improves the condition of by-caught blue sharks without affecting the CPUE or size of the target species. In conclusion, the use of a C-type hook could reduce the detrimental effects of by-catch on some species in the Adriatic Sea; however, this finding needs to be confirmed by a study with a larger sample size.

Thymic alterations resulting from experimental visceral leishmaniasis in a Syrian hamster (Mesocricetus auratus) - Karen Santos Março; Jaqueline da Silva Borégio; Giulia Gonçalves Jussiani; Laura Flávia Esperança de Souza Ferreira; Gabriela Venicia Araujo Flores; Carmen Maria Sandoval Pacheco; Marcia Dalastra Laurenti; Gisele Fabrino Machado (Veterinary Immunology and Immunopathology, 2023)

Different salt stress response in Kalanchoe plants during vegetative and asexual propagation - Giulia Atzori; Stefania Caparrotta (South African Journal of Botany, 2023)

A spectroscopic study on orthodontic aligners: First evidence of secondary microplastic detachment after seven days of artificial saliva exposure - Vincenzo Quinzi; Giulia Orilisi; Flavia Vitiello; Valentina Notarstefano; Giuseppe Marzo; Giovanna Orsini (Science of The Total Environment, 2023)

Multidisciplinary long-term survey of Manila clam grown in farming sites subjected to different environmental conditions - Massimo Milan; Ilaria Bernardini; Camilla Bertolini; Giulia Dalla Rovere; Alice Manuzzi; Roberto Pastres; Luca Peruzza; Morgan Smits; Jacopo Fabrello; Cristina Breggion; Andrea Sambo; Luciano Boffo; et al. (Science of The Total Environment, 2023)

Calcium phosphates from fish bones in sunscreen: An LCA and toxicity study of an emerging material for circular economy - Serena Righi; Ermelinda Prato; Giulia Magnani; Virginia Lama; Francesca Biandolino; Isabella Parlapiano; Francesca Carella; Michele Iafisco; Alessio Adamiano (Science of The Total Environment, 2023)

Entomopathogenic nematodes for biological control of Psylliodes chrysocephala (Coleoptera: Chrysomelidae) in oilseed rape - Giulia Godina; Bart Vandenbossche; Maja Schmidt; Aviel Sender; Akwo Hanson Tambe; Maria Touceda-González; Ralf-Udo Ehlers (Journal of Invertebrate Pathology, 2023)

Genetic variability of Metarhizium isolates from the Ticino Valley Natural Park (Northern Italy) as a possible microbiological resource for the management of Popillia japonica - Gian Paolo Barzanti; Jürg Enkerli; Claudia Benvenuti; Agostino Strangi; Giuseppe Mazza; Giulia Torrini; Stefania Simoncini; Francesco Paoli; Leonardo Marianelli (Journal of Invertebrate Pathology, 2023)

Hydro-mechanical behaviour of a cement–bentonite mixture along evaporation and water-uptake controlled paths - Guido Musso; Vincenzo Sergio Vespo; Giulia Guida; Gabriele Della Vecchia (Geomechanics for Energy and the Environment, 2023)

The Green New Deal: Historical insights and local prospects in the United Kingdom (UK) - Donal Brown; Marie-Claire Brisbois; Max Lacey-Barnacle; Tim Foxon; Claire Copeland; Giulia Mininni (Ecological Economics, 2023)

Proteomics to study cancer immunity and improve treatment - Giulia Franciosa; Anders H. Kverneland; Agnete W. P. Jensen; Marco Donia; Jesper V. Olsen (Seminars in Immunopathology, 2023)
Cancer survival and progression depend on the ability of tumor cells to avoid immune recognition. Advances in the understanding of cancer immunity and tumor immune escape mechanisms enabled the development of immunotherapeutic approaches. In patients with otherwise incurable metastatic cancers, immunotherapy resulted in unprecedented response rates with the potential for durable complete responses. However, primary and acquired resistance mechanisms limit the efficacy of immunotherapy. Further therapeutic advances require a deeper understanding of the interplay between immune cells and tumors. Most high-throughput studies within the past decade focused on an omics characterization at DNA and RNA level. However, proteins are the molecular effectors of genomic information; therefore, the study of proteins provides deeper understanding of cellular functions. Recent advances in mass spectrometry (MS)-based proteomics at a system-wide scale may allow translational and clinical discoveries by enabling the analysis of understudied post-translational modifications, subcellular protein localization, cell signaling, and protein–protein interactions. In this review, we discuss the potential contribution of MS-based proteomics to preclinical and clinical research findings in the context of tumor immunity and cancer immunotherapies.

Hydromorphological discontinuities deeply modify the benthic multi-species assemblage diversity in a Mediterranean running river - Giulia Cesarini; Luca Gallitelli; Lorenzo Traversetti; Tiziana Bandini; Massimiliano Scalici (Rendiconti Lincei. Scienze Fisiche e Naturali, 2023)

The Il Torno collapsed basin-margin tract and rockfall deposits: the stunning snapshot of a preserved Jurassic submarine topography in the Longobucco Basin (Calabria, Italy) - Simone Fabbi; Giulia Innamorati; Nino Mariotti; Massimo Santantonio (International Journal of Earth Sciences, 2023)

Effect of optic flow on spatial updating: insight from an immersive virtual reality study - Lisa Cardelli; Maria Giulia Tullo; Gaspare Galati; Valentina Sulpizio (Experimental Brain Research, 2023)

Klebsiella pneumoniae carrying multiple alleles of antigen 43-encoding gene of Escherichia coli associated with biofilm formation - Martina Tambassi; Elena Passarini; Ilaria Menozzi; Melissa Berni; Chiara Bracchi; Alessandra Dodi; Luca Bolzoni; Erika Scaltriti; Marina Morganti; Giulia Ferrarini; Laura Sordi; Mario Sarti; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2023)
A clinical strain of Klebsiella pneumoniae typed as sequence type 307 carrying three different alleles of the flu gene encoding the Escherichia coli virulence factor antigen 43 associated with biofilm formation was detected and characterized. The flu alleles are located in the chromosome inside putative integrative conjugative elements. The strain displays the phenotypes associated with Ag43, i.e. bi-phasic colony morphology and enhanced biofilm production. Furthermore, the strain produces low amount of capsule known to affect Ag43 function. Analysis of 1431 worldwide deposited genomes revealed that 3.7% Klebsiella pneumoniae carry one or two flu alleles.

Optimal plant water use strategies explain soil moisture variability - Maoya Bassiouni; Stefano Manzoni; Giulia Vico (Advances in Water Resources, 2023)

Stress–Strain Assessment of Honeycomb Sandwich Panel Subjected to Uniaxial Compressive Load - Pasqualino Corigliano; Giulia Palomba; Vincenzo Crupi; Yordan Garbatov (Journal of Marine Science and Engineering, 2023)
The ship hull structure is composed of plates and stiffened panels. Estimating the maximum load-carrying capacity, or the ultimate strength, of these structural components is fundamental. One of the main challenges nowadays is the implementation of new materials and technologies to enhance the structural integrity, economy, safety and environmentally friendly design of the ship’s hull structure. A new design solution may be represented by aluminium alloy honeycomb sandwich structures, both as plane panels or stiffened ones, which are characterised by excellent impact-absorption capabilities and a high stiffness-to-weight ratio. Still, their response to some conditions typical of ship structural design needs to be deeply investigated. Axial compressive loading is one of the most critical conditions that could impact the structural integrity of such light-weight solutions. Hence, the uniaxial compressive behaviour of aluminium honeycomb sandwich structures has to be deeply investigated to promote their integration in ship structural design. Within this context, the present work performs an experimental and numerical study of a honeycomb sandwich panel subjected to uniaxial compressive loads. The results will help develop models for predicting the uniaxial compressive load-carrying capacity of hybrid honeycomb sandwiches of aluminium alloy design.

Mitochondrial DNA diversity and genetic structure of striped dolphin Stenella coeruleoalba in the Northern Ionian Sea - Rachele Antonacci; Giovanna Linguiti; Federica Paradiso; Chiara Scalone; Carmelo Fanizza; Elena Ciani; Giulia Cipriano; Salvatrice Ciccarese; Roberto Carlucci (Frontiers in Marine Science, 2023)
In the framework of global and EU policies focused on stopping the loss of biodiversity process, deepening the genetic variability, especially of populations species identified as threatened, is crucial for defining conservation units and developing appropriate conservation strategies. This is more urgent for cetacean species in the Mediterranean because they assume a key ecological role in the marine food web and are severely affected by numerous and different anthropogenic pressures. This study aims to increase information on the genetic variability of striped dolphin in the Northern Ionian Sea by investigating the population structure, phylogenetic relationships and phylogeographic patterns using two mtDNA markers. From October 2020 to August 2021, a total of 88 skin tissue samples were collected from free-ranging dolphins in the Gulf of Taranto by applying the non-invasive technique of skin swabbing. An acceptable amount of DNA was extracted from 86 samples and used for subsequent genetic analysis conducted on the partial sequences of 421 and 704 bp in length of the cytb gene and D-loop control region, respectively. In addition, the sequences of the two mtDNA markers were joined together to compose a mtDNA concatenated sequence of 1125 bp for each sampled dolphin in order to investigate the genetic variability of the species population in the study area. Genetic analysis highlighted a low nucleotide diversity and high haplotypic diversity of the striped dolphin of the Gulf of Taranto, suggesting a population in rapid expansion after a period of reduction in size and diversity of the initial population. The phylogenetic analyses revealed the presence of at least two different lineages of Stenella coeruleoalba in the Mediterranean Sea, one specific to the Northern Ionian Sea and one shared with the Mediterranean population, confirming results already obtained for the local unit in the Gulf of Taranto. The results point out a potential problem of hybridization between striped and common dolphins which needs to be further investigated. Therefore, increasing the analysis of several markers may increase understanding of the genetic diversity of the population in the Ionian Sea and represent a useful tool to support the implementation of future effective conservation measures.

Anthropic impact on soil heavy metal contamination in riparian ecosystems of northern Algeria - Pasquale Napoletano; Noureddine Guezgouz; Erika Di Iorio; Claudio Colombo; Giulia Guerriero; Anna De Marco (Chemosphere, 2023)

Remote sensing crop group-specific indicators to support regional yield forecasting in Europe - Giulia Ronchetti; Giacinto Manfron; Christof J. Weissteiner; Lorenzo Seguini; Luigi Nisini Scacchiafichi; Lorenzo Panarello; Bettina Baruth (Computers and Electronics in Agriculture, 2023)

IoT based dynamic Bayesian prediction of crop evapotranspiration in soilless cultivations - Alexander Kocian; Giulia Carmassi; Fatjon Cela; Stefano Chessa; Paolo Milazzo; Luca Incrocci (Computers and Electronics in Agriculture, 2023)

Feeding gilthead sea bream with increasing dietary bacterial single cell protein level: Implication on growth, plasma biochemistry, gut histology, and gut microbiota - Arianna Marchi; Alessio Bonaldo; Daniel Scicchitano; Marco Candela; Antonina De Marco; Salvatore Falciglia; Maurizio Mazzoni; Giulia Lattanzio; Paolo Clavenzani; Francesco Dondi; Pier Paolo Gatta; Luca Parma (Aquaculture, 2023)

Full-scale activated sludge transplantation reveals a highly resilient community structure - Giulia Dottorini; Dorottya Sarolta Wágner; Mikkel Stokholm-Bjerregaard; Sergey Kucheryavskiy; Thomas Yssing Michaelsen; Marta Nierychlo; Miriam Peces; Rohan Williams; Per Henrik Nielsen; Kasper Skytte Andersen; Per Halkjær Nielsen (Water Research, 2023)

Case – Control study: Evaluation of plasma procalcitonin concentration as an indicator of inflammation in healthy and sick cows - Francesca Bonelli; Alessio Madrigali; Micaela Sgorbini; Valentina Meucci; Federica Battaglia; Monika Guélat-Brechbuehl; Giulia Sala; Mireille Meylan (Research in Veterinary Science, 2023)

A chronologically reliable record of 17,000 years of biomass burning in the Lake Victoria area - Yunuen Temoltzin-Loranca; Erika Gobet; Boris Vannière; Jacqueline F.N. van Leeuwen; Giulia Wienhues; Sönke Szidat; Colin Courtney-Mustaphi; Mary Kishe; Moritz Muschick; Ole Seehausen; Martin Grosjean; Willy Tinner (Quaternary Science Reviews, 2023)

Effects of high temperature and marine heat waves on seagrasses: Is warming affecting the nutritional value of Posidonia oceanica? - Patrizia Stipcich; Pedro Beca-Carretero; Xosé Antón Álvarez-Salgado; Eugenia T. Apostolaki; Niki Chartosia; Pavlos Theofilos Efthymiadis; Carlos E. Jimenez; Gabriella La Manna; Arianna Pansini; Elena Principato; Vasilis Resaikos; Dagmar B. Stengel; et al. (Marine Environmental Research, 2023)

EEG in extreme conditions: An advanced analysis pipeline for the human electroencephalographic signals recorded in space during the ALTEA experiment - Sara Sommariva; Giulia Romoli; Elisabetta Vallarino; Luca Di Fino; Alberto Sorrentino; Giorgia Santi Amantini; Walter G. Sannita; Michele Piana; Livio Narici (Life Sciences in Space Research, 2023)

Mouse genomic associations with in vitro sensitivity to simulated space radiation - Egle Cekanaviciute; Duc Tran; Hung Nguyen; Alejandra Lopez Macha; Eloise Pariset; Sasha Langley; Giulia Babbi; Sherina Malkani; Sébastien Penninckx; Jonathan C. Schisler; Tin Nguyen; Gary H. Karpen; et al. (Life Sciences in Space Research, 2023)

Comparison of Four Arteries for Invasive Blood Pressure Measurements and Dixtal 2010 Oscillometric Values in Horses Anesthetized With Isoflurane: Does the Artery Matter? - Monica Midon; Diego I. Yamada; Darcio Zangirolami Filho; Giulia C. Simionato; Walter H. Feringer Junior; Gabriel Conde; Erik H. Hofmeister (Journal of Equine Veterinary Science, 2023)

Conceptual design and techno-economic assessment of coupled hydrothermal liquefaction and aqueous phase reforming of lignocellulosic residues - Edoardo Tito; Giulia Zoppi; Giuseppe Pipitone; Edoardo Miliotti; Arturo Di Fraia; Andrea Maria Rizzo; Raffaele Pirone; David Chiaramonti; Samir Bensaid (Journal of Environmental Chemical Engineering, 2023)

Role of neuronal and non-neuronal acetylcholine signaling in Drosophila humoral immunity - Giorgia Giordani; Giulia Cattabriga; Andrea Becchimanzi; Ilaria Di Lelio; Giovanna De Leva; Silvia Gigliotti; Francesco Pennacchio; Giuseppe Gargiulo; Valeria Cavaliere (Insect Biochemistry and Molecular Biology, 2023)

Determinants of the willingness to buy products certified by omics technology: differences between regular and occasional consumers of organic food - Giulia Sesini; Greta Castellini; Paola Iannello; Linda Lombi; Edoardo Lozza; Luigi Lucini; Guendalina Graffigna (Food Research International, 2023)