Multi-Directional and Multiphase Tectonic Modification, and Hydrocarbon Differential Enrichment in the Middle-Upper Yangtze Region - Zhiliang He; Shuangjian Li; Yingqiang Li; Jian Gao (Journal of Earth Science, 2022)

Nocardiopsis akebiae sp. nov., a novel endophytic actinomycete isolated from fruits of Akebia trifoliata - Ping Mo; Jinhua Zhou; Fumin Zhou; Jiang He; Wansheng Zou; Jian Gao (Archives of Microbiology, 2022)

Wheat genomic study for genetic improvement of traits in China - Jun Xiao; Bao Liu; Yingyin Yao; Zifeng Guo; Haiyan Jia; Lingrang Kong; Aimin Zhang; Wujun Ma; Zhongfu Ni; Shengbao Xu; Fei Lu; Yuannian Jiao; et al. (Science China Life Sciences, 2022)

Improved Pharmaceutical Properties of Honokiol via Salification with Meglumine: an Exception to Oft-quoted ∆pKa Rule - Xiaoshuang He; Yuanfeng Wei; Shiru Wang; Jianjun Zhang; Yuan Gao; Shuai Qian; Zunting Pang; Weili Heng (Pharmaceutical Research, 2022)

Heme oxygenase-1 protects against endotoxin-induced acute lung injury depends on NAD+-mediated mitonuclear communication through PGC1α/PPARγ signaling pathway - Simeng He; Jia Shi; Wenming Liu; Shihan Du; Yuan Zhang; Lirong Gong; Shuan Dong; Xiangyun Li; Qiaoying Gao; Jing Yang; Jianbo Yu (Inflammation Research, 2022)

Uncertainty or trust? Political trust, perceived uncertainty and public acceptance of personal carbon trading policy - Lan Gao; Jingjing Jiang; Haonan He; Qi Zhou; Shanyong Wang; Jun Li (Environmental Geochemistry and Health, 2022)

What drives resident acceptance of personal carbon trading policy in China? - Lan Gao; Haonan He; Shanyong Wang; Jun Li (Environmental Geochemistry and Health, 2022)

Ameliorating Inflammation in Insulin-resistant Rat Adipose Tissue with Abdominal Massage Regulates SIRT1/NF-κB Signaling - Tianjiao Gao; Shaotao Chen; Yiran Han; Dongmei Zhang; Yi Tan; Yutao He; Mingjun Liu (Cell Biochemistry and Biophysics, 2022)
It was the aim of this study to determine whether abdominal massage reverses high-fat diet-induced insulin resistance compared with RSV treatment. A total of sixty male Sprague-Dawley rats were randomly placed in one of four groups:the non-fat diet (NFD), the high-fat diet (HFD), the HFD with abdominal massage (HFD+ AM), and the HFD plus resveratrol (HFD+ RSV). For eight weeks, rats were fed high-fat diets to create insulin resistance, followed by six weeks of either AM or RSV. Molecular mechanisms of adipogenesis and cytokine production in rats with high-fat diets were investigated. The model rat adipose tissue showed significant improvements in obesity, glucose intolerance, and the accumulation of lipid in the body [the total cholesterol level (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C)], metabolic effects of glucose [The fasting blood glucose (FBG), Fasting insulin levels (FINS)], inflammatory status [interleukin-6 (IL-6) and tumor necrosis factor (TNF)-α, C-reactive protein (CRP)], and macrophage polarization after AM or RSV treatment. Further, AM increased SIRT1/NF-κB signaling in rat adipose tissue. Accordingly, in rat adipose tissue, our results indicate that AM regulates the secretion of proinflammatory cytokines, blood sugar levels, and related signaling pathways, contributing to improvement of IR, which may serves as a new therapeutic approach for the treatment for IR.

Preparation of Ni-La/Al2O3-CeO2-Bamboo Charcoal Catalyst and Its Application in Co-pyrolysis of Straw and Plastic for Hydrogen Production - Yiran Zhang; Jianfen Li; Bolin Li; Zeshan Li; Yun He; Zhenhua Qin; Rongyi Gao (BioEnergy Research, 2022)

Mechanical property and mechanism of salt rock enhanced by lime and silica fume - Jiangping Gao; Yuan He; Xiangdong Cui (Arabian Journal of Geosciences, 2022)

Hyphomonas sediminis sp. nov., isolated from marine sediment - Lu Wang; Wei He; Zeng-Yu Gao; Dao-Feng Zhang; Jian-Ke Huang; Chuang Liu; Wen-Jun Li; Ai Hua Zhang (Antonie van Leeuwenhoek, 2022)

CHLNET: A novel hybrid 1D CNN-SVR algorithm for estimating ocean surface chlorophyll-a - Donglin Fan; Hongchang He; Ruisheng Wang; You Zeng; Bolin Fu; Yuankang Xiong; Lilong Liu; Yong Xu; Ertao Gao (Frontiers in Marine Science, 2022)
Developing a unified chlorophyll-a (Chla) inversion algorithm for cross-water types is a significant challenge owing to the insufficiency of input features and training samples. Although machine learning algorithms can build a consistent model for different trophic waters, the accuracy of the inversion is dependent on the quality of the extended features. Here, we designed a novel hybrid framework called CHLNET, which combines a one-dimensional convolutional neural network (1D CNN) and support vector regression (SVR). The 1D CNN is used to extract features from the original band features, and the SVR is used to perform a fit of Chla. CHLNET is trained and tested using match-up pairs of SeaWiFS remote sensing reflectance [Rrs(λ)] in situ with Chla ranging from 0.009 mg/m³ to 138.046 mg/m³, which covers mostly ocean water types. Performance metrics in the log space of CHLNET were better than those of the state-of-the-art algorithms on the testing dataset, and CHLNET had the best overall performance with the largest cover area in the star plot. The frequency distribution of predicted Chla by CHLNET was more consistent with that of in situ Chla. While the spatial pattern was not smooth in low Chla concentration waters, CHLNET demonstrated excellent mapping ability at the global and local scales in high Chla concentration waters. Through the band-shift method, which transfers the Rrs(λ) of MERIS and MODIS-Aqua to the Rrs(λ) of SeaWiFS in the visible spectral range, CHLNET obtained better accuracy than the blended algorithm of OCx and CI on MERIS and MODIS-Aqua matchups, which validates the generalization of CHLNET on cross-sensor types. The results indicate that CHLNET avoids the drawbacks of manually constructing extended features and the need for merging water type-appropriate algorithms for Chla retrieval, as well as provides a new idea for unified Chla concentration inversion across water types. Thus, CHLNET may serve as an alternative approach for Chla inversion.

Deciphering the Heterogeneity of Mitochondrial Functions During Hematopoietic Lineage Differentiation - Haoyue Liang; Shuxu Dong; Weichao Fu; Sen Zhang; Wenying Yu; Fang Dong; Baolin He; Jinhong Wang; Yingdai Gao; Yuan Zhou; Yongxin Ru (Stem Cell Reviews and Reports, 2022)

Fracability Evaluation Based on the Three-Dimensional Geological Numerical Simulation of In Situ Stress: Case Study of the Longmaxi Formation in the Weirong Shale Gas Field, Southwestern China - Ze Li; Gao Li; Hao Yu; Long He; Zujun Jiang; Hongzhi Li; Hanbo Gong (Mathematical Geosciences, 2022)

Directional Support Method for Tunnel Jointed Rock Mass - Xu Wu; Jinliang Xu; Liyuan Zhang; Jinglai Sun; Zhengyu He; Jun Gao (Geotechnical and Geological Engineering, 2022)

Diversity and functions of quorum sensing bacteria in the root environment of the Suaeda glauca and Phragmites australis coastal wetlands - Changfei He; Li Zheng; Wei Gao; Jinfeng Ding; Chengxuan Li; Xiyuan Xu; Bin Han; Qian Li; Shuai Wang (Environmental Science and Pollution Research, 2022)

Linkages among the functional traits, insect visitation rate and seed set of Gentiana taxa on the Tibetan Plateau - Wen-fei Dai; Rui Gao; Meng-ying He; Yu-lian Yang; Fang-lan Li; Jun-peng Mu (Journal of Mountain Science, 2022)

Changes in Global Vegetation Distribution and Carbon Fluxes in Response to Global Warming: Simulated Results from IAP-DGVM in CAS-ESM2 - Xiaofei Gao; Jiawen Zhu; Xiaodong Zeng; Minghua Zhang; Yongjiu Dai; Duoying Ji; He Zhang (Advances in Atmospheric Sciences, 2022)

Elastic full waveform inversion in VTI media using logging data constraints and gradient precondition - Yipeng Xu; Kai Zhang; Zhenchun Li; Zilin He; Jinfeng Gao; Xianyang Zhao (Acta Geophysica, 2022)

Evaluation of LAI Estimation of Mangrove Communities Using DLR and ELR Algorithms With UAV, Hyperspectral, and SAR Images - Bolin Fu; Jun Sun; Yeqiao Wang; Wenlan Yang; Hongchang He; Lilong Liu; Liangke Huang; Donglin Fan; Ertao Gao (Frontiers in Marine Science, 2022)
The high-precision estimation of mangrove leaf area index (LAI) using a deep learning regression algorithm (DLR) always requires a large amount of training sample data. However, it is difficult for LAI field measurements to collect a sufficient amount of sample data in mangrove wetlands. To tackle this challenge, this paper proposed an approach for expanding training samples and quantitatively evaluated the performance of estimating LAI for mangrove communities using Deep Neural Networks (DNN) and Transformer algorithms. This study also explored the effects of unmanned aerial vehicle (UAV) and Sentinel-2A multispectral, orbital hyper spectral (OHS), and GF-3 SAR images on LAI estimation of different mangrove communities. Finally, this paper evaluated the LAI estimation ability of mangrove communities using ensemble learning regression (ELR) and DLR algorithms. The results showed that: (1) the UAV images achieved the better LAI estimation of different mangrove communities (R 2 = 0.5974–0.6186), and GF-3 SAR images were better for LAI estimation of Avicennia marina with high coverage (R 2 = 0.567). The optimal spectral range for estimating LAI for mangroves in the optical images was between 650–680 nm. (2) The ELR model outperformed single base model, and produced the high-accuracy LAI estimation (R 2 = 0.5266–0.713) for different mangrove communities. (3) The average accuracy (R 2 ) of the ELR model was higher by 0.0019–0.149 than the DLR models, which demonstrated that the ELR model had a better capability (R 2 = 0.5865–0.6416) in LAI estimation. The Transformer-based LAI estimation of A. marina (R 2 = 0.6355) was better than the DNN model, while the DNN model produced higher accuracy for Kandelia candel (KC) (R 2 = 0.5577). (4) With the increase in the expansion ratio of the training sample (10–50%), the LAI estimation accuracy (R 2 ) of DNN and Transformer models for different mangrove communities increased by 0.1166–0.2037 and 0.1037–0.1644, respectively. Under the same estimation accuracy, the sample enhancement method in this paper could reduce the number of filed measurements by 20–40%.

Rainstorm-induced large-scale landslides in Northeastern Chongqing, China, August 31 to September 2, 2014 - Bin Li; Yang Gao; Yueping Yin; Jiawei Wan; Kai He; Weile Wu; Han Zhang (Bulletin of Engineering Geology and the Environment, 2022)

In-situ high-pressure and high-temperature spectroscopic studies of phengite in ultrahigh-pressure eclogite: implications for water transport during ultra-deep continental subduction - Xuejing He; Li Zhang; Hiroyuki Kagi; Joseph R. Smyth; Kazuki Komatsu; Xiaoguang Li; Jing Gao; Li Lei (Physics and Chemistry of Minerals, 2022)

The complete chloroplast genome of Carpesium abrotanoides L. (Asteraceae): structural organization, comparative analysis, mutational hotspots and phylogenetic implications within the tribe Inuleae - Xiangyu He; Shujie Dong; Chenshu Gao; Qirui Wang; Manjia Zhou; Rubin Cheng (Biologia, 2022)

Environmental sustainability in the city of Shanghai municipal solid waste treatment system: an integrated framework of artificial neural network (ANN) and LCA-emergy methodology - Junxue Zhang; Ashish T. Asutosh; He Zhang; Yanyan Yan; Yan Zhang; Guobin Wei; Cheng Ma; Yaling Shi; Yuchen Gao; Xiangdong Yan; Kun Xing; Yuanliang Dong; et al. (Arabian Journal of Geosciences, 2022)

The Welfare of Nile Tilapia (Oreochromis niloticus, GIFT Strain) Juveniles Cultured in Different Light Spectra - Mengmeng Yi; Wanting Zhai; Miao Wang; He Wang; Zhigang Liu; Fengying Gao; Xiaoli Ke; Changbin Song; Jianmeng Cao; Maixin Lu (Frontiers in Marine Science, 2022)
The light spectrum is a vital environmental factor for the culture of fish, and the welfare of farmed fish is a crucial issue in aquaculture. In this study, Nile tilapia ( Oreochromis niloticus , GIFT strain) juveniles were exposed to full-spectrum (LW), red (LR), yellow (LY), or blue (LB) light. After the 45-day experiment, growth performance, stress responses, and aggressive behaviors were evaluated, and transcriptomic analysis was carried out. The results revealed that LW and LR positively affected growth performance. At the same time, LY and LB had a negative effect. Light spectrum induced stress responses of juvenile fish exposed to LY, under which the total antioxidant capacity (T-AOC) and cortisol (COR) contents were the highest. The activities of α-amylase (AMS), protease (PES), and lipase (LPS) in the digestive tract showed a similar tendency, indicating that the light spectra altered the digestive enzyme activities and then affected growth. Behavioral analyses showed increased chase and bite activities of tilapia juveniles exposed to LW and LY. The affected functions included the nervous system, muscle morphogenesis, and immune system-related regulation. Enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways include the tryptophan metabolism signaling pathway, protein digestion and absorption signaling pathway, Jak-STAT signaling pathway, arachidonic acid metabolism signaling pathway, and alpha-linolenic acid metabolism signaling pathway. Overall, light spectra influenced the welfare of farmed tilapia juveniles in terms of growth, stress, and behavior. Our results suggested that LR should be used in juvenile tilapia culture.

Large-scale evaluation of aluminum tolerance in maize (Zea mays L.) acessions - Jianzhou Ding; Wei Yang; Xiaoqi Hu; Weina Yan; Wanpeng Hu; Hongjie Li; Chan Liu; Wenzhu He; Yanli Lu; Shibin Gao; Suzhi Zhang (Theoretical and Experimental Plant Physiology, 2022)

Metabolic Regulation: A Potential Strategy for Rescuing Stem Cell Senescence - Wenxin Zhang; Jiayu Li; Yuchi Duan; Yanlin Li; Yanan Sun; Hui Sun; Xiao Yu; Xingyu Gao; Chang Zhang; Haiying Zhang; Yingai Shi; Xu He (Stem Cell Reviews and Reports, 2022)

Alfalfa green manure amendment improved P use efficiency and reduced P losses from paddy fields - Xiaoye Gao; Yan He; Tao Zhang; Yuan An; Caili Sun; Hongyun Xu; Xiaodan Wang (Nutrient Cycling in Agroecosystems, 2022)

The SACT Template: A Human Brain Diffusion Tensor Template for School-age Children - Congying Chu; Haoran Guan; Sangma Xie; Yanpei Wang; Jie Luo; Gai Zhao; Zhiying Pan; Mingming Hu; Weiwei Men; Shuping Tan; Jia-Hong Gao; Shaozheng Qin; et al. (Neuroscience Bulletin, 2022)

An AHP-based regional COVID-19 vulnerability model and its application in China - Zekun Gao; Yutong Jiang; Junyu He; Jiaping Wu; Jian Xu; George Christakos (Modeling Earth Systems and Environment, 2022)

Peroxymonosulfate activation by Co-doped magnetic Mn3O4 for degradation of oxytetracycline in water - Liyan He; Hui Li; Jianzhi Wang; Qifei Gao; Xiaoli Li (Environmental Science and Pollution Research, 2022)

Effects of bedform migration on nutrient fluxes at the sediment–water interface: a theoretical analysis - Lei Huang; Qifeng Gao; Hongwei Fang; Guojian He; Danny Reible; Dianchang Wang; Xinghua Wu (Environmental Fluid Mechanics, 2022)

Early landslide mapping with slope units division and multi-scale object-based image analysis — A case study in the Xianshui River basin of Sichuan, China - Hui Gao; Li He; Zheng-wei He; Wen-qian Bai (Journal of Mountain Science, 2022)

LWIR hyperspectral image classification based on a temperature-emissivity residual network and conditional random field model - Liqin Cao; Jiani He; Lyuzhou Gao; Yanfei Zhong; Xin Hu; Zhijiang Li (International Journal of Remote Sensing, 2022)

Heterologous expression and characterization of two novel glucanases derived from sheep rumen microbiota - De-Ying Gao; Xiao-Bao Sun; Ying Fang; Bo He; Jun-Hong Wang; Jian-Xin Liu; Jia-Kun Wang; Qian Wang (World Journal of Microbiology and Biotechnology, 2022)

Construction and application of debris flow infrasound real-time monitoring and warning visualization platform - Dunlong Liu; Qian Wu; Hanchuan Dong; Xiaopeng Leng; Lei He; Yan Gao (Natural Hazards, 2022)

The Epigenetic Regulation of OLIG2 by Histone Demethylase KDM6B in Glioma Cells - Aixia Sui; Biaogang Han; Wenjun Ren; Weiliang He; Chao Gao; Xiaohui Han; Shifeng Liu; Yan Zhang; Xueling Qi; Xiaoqiang Guo (Journal of Molecular Neuroscience, 2022)

Comparative transcriptome analyses reveal genes related to pigmentation in the petals of a flower color variation cultivar of Rhododendron obtusum - Xiaobo Sun; Lisi He; Zhenhao Guo; Zheng Xiao; Jiale Su; Xiaoqing Liu; Huimin Zhou; Chang Li; Haidong Gao (Molecular Biology Reports, 2022)

Novel bioavailability-based risk assessment of Cd in earthworms and leeches utilizing in vitro digestion/Caco-2 and MDCK cells - Tian-tian Zuo; Fei-ya Luo; Huai-zhen He; Hong-yu Jin; Lei Sun; Shu-xia Xing; Bo Li; Fei Gao; Shuang-cheng Ma; Lang-chong He (Environmental Science and Pollution Research, 2022)

Temporal and spatial analysis of the ecosystem service values in the Three Gorges Reservoir area of China based on land use change - Xu Zhao; Ping Yi; Jingjing Xia; Weijun He; Xin Gao (Environmental Science and Pollution Research, 2022)

The Pingdi landslide in Shuicheng, Guizhou, China: instability process and initiation mechanism - Kai He; Jun Li; Bin Li; Zhinan Zhao; Chaoying Zhao; Yang Gao; Zheng Liu (Bulletin of Engineering Geology and the Environment, 2022)

Effects of synthetic nitrification inhibitor (3,4-dimethylpyrazole phosphate; DMPP) and biological nitrification inhibitor (methyl 3-(4-hydroxyphenyl) propionate; MHPP) on the gross N nitrification rate and ammonia oxidizers in two contrasting soils - Ting Lan; Mengxiao Li; Xiaoqian He; Ouping Deng; Wei Zhou; Ling Luo; Guangdeng Chen; Shu Yuan; Jing Ling; Min Zeng; Xuesong Gao (Biology and Fertility of Soils, 2022)

Transcriptome Sequencing of the Pale Anemones (Exaiptasia diaphana) Revealed Functional Peptide Gene Resources of Sea Anemone - Jinxing Fu; Yanbin He; Chao Peng; Tianle Tang; Aihua Jin; Yanling Liao; Qiong Shi; Bingmiao Gao (Frontiers in Marine Science, 2022)
Sea anemone venom is a marine drug resource library with pharmacological and biotechnology value, and it contains complex and diverse functional peptide neurotoxins. However, the venom components of only a limited number of sea anemone species have been globally evaluated by transcriptomics and proteomics. In this study, 533 putative protein as well as peptide toxin sequences were found on a large scale from dissimilar developmental stages of sea anemone Exaiptasia diaphana , which can be divided into 75 known superfamilies according to the predicted functions. Among them, the proportion of protein is 72.98%, and its main families are metalloproteases, chymotrypsinogen like, collagen, pancreatic lipase-associated protein like, and G-protein coupled receptor, while the proportion of peptides is 27.02%, and main families are ShK domain, thrombin, Kunitz-type, defensin, as well as insulin-like peptide. Finally, typical anemone peptide neurotoxins were screened, and the 3D structure and pharmacological activity of these anemone peptide neurotoxins were predicted by homology modeling. We elucidate on a valuable high-throughput approach for obtaining sea anemone proteins and peptides. Our findings form the basis for targeted studies on the diversity as well as pharmacological effects of sea anemone peptide neurotoxins.

Effects of roasting and deodorisation on 3-monochloropropane-1, 2-diol esters, 3, 4-benzopyrene and trans fatty acids in peanut oil - Pan Gao; Yuling Zheng; Hui Liu; Wei Yang; Chuanrong Hu; Dongping He (Food Additives & Contaminants: Part A, 2022)

Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.) - Yan Dong; Dengan Xu; Xiaowan Xu; Yan Ren; Fengmei Gao; Jie Song; Aolin Jia; Yuanfeng Hao; Zhonghu He; Xianchun Xia (Theoretical and Applied Genetics, 2022)

Early changes to the extracellular space in the hippocampus under simulated microgravity conditions - Yajuan Gao; Hongbin Han; Jichen Du; Qingyuan He; Yanxing Jia; Junhao Yan; Hui Dai; Bin Cui; Jing Yang; Xunbin Wei; Liu Yang; Rui Wang; et al. (Science China Life Sciences, 2022)

Trends and environmental factors of arsenic in sediments from the five lake ecoregions, China - Jinli Zheng; Bin Zhou; Hao Li; Manshu Gao; Changwei Lü; Jiang He (Environmental Science and Pollution Research, 2022)

Removal of SO2 from flue gas using blast furnace dust as an adsorbent - Binghua Xie; Na Geng; Qian Yu; Di He; Fang Wang; Tiancheng Liu; Jiyun Gao; Ping Ning; Xin Song; Lijuan Jia (Environmental Science and Pollution Research, 2022)

Nitrogen Limitation Enhanced Calcification and Sinking Rate in the Coccolithophorid Gephyrocapsa oceanica Along With Its Growth Being Reduced - Xiaowen Jiang; He Li; Shanying Tong; Kunshan Gao (Frontiers in Marine Science, 2022)
Phytoplankton are exposed to different concentrations of nutrients in different waters along with changing light levels during diurnal and seasonal cycles. We grew the coccolithophorid Gephyrocapsa oceanica semi-continuously at different nitrate levels under indoor low and outdoor high light conditions, and found that reduced nitrate availability significantly increased its production of particulate inorganic carbon (PIC), with its growth being reduced. High light treatment suppressed the growth of nitrate-limited cells and their efficiency of N assimilation by up to 63% compared to low light treatment. The combination of high light and nitrate limitation increased contents of PIC per cell due to sustained photochemical energy transfer, resulting in faster sinking rates by up to 82% in comparison with nitrate-repleted cells. Additionally, the sinking rates were positively correlated with ratios of PIC to particulate organic carbon (POC). These results imply that coccolithophores distributed in oligotrophic waters could be more effective as the ballast in aggregates, facilitating particulate organic carbon flux to deeper waters.

Mesoporous Silica Carrier-Based Composites for Taste-Masking of Bitter Drug: Fabrication and Palatability Evaluation - Weifeng Zhang; Guoxiang Li; Chaoqiang Xiao; Xin Chang; Ying Sun; Weiping Fan; Bing Tian; Di Gao; Yao Xiao; Xueping Wu; Shuwang He; Guangxi Zhai (AAPS PharmSciTech, 2022)

Removal of perchlorate by a lab-scale constructed wetland using achira (Canna indica L.) - Dongqin Li; Bingqian Li; Haishuo Gao; Xinyu Du; Junhao Qin; Huashou Li; Hongzhi He; Guikui Chen (Wetlands Ecology and Management, 2022)

Cancer metabolism and tumor microenvironment: fostering each other? - Yiyuan Yuan; Huimin Li; Wang Pu; Leilei Chen; Dong Guo; Hongfei Jiang; Bo He; Siyuan Qin; Kui Wang; Na Li; Jingwei Feng; Jing Wen; et al. (Science China Life Sciences, 2022)

Experimental and Numerical Studies on Small-Scale Direct Tension Test for Rock - Gao-Feng Zhao; Yuliang Zhang; Senwei Hou; Lei He (Rock Mechanics and Rock Engineering, 2022)

A Machine Learning Methodology for Predicting Geothermal Heat Flow in the Bohai Bay Basin, China - Jifu He; Kewen Li; Xinwei Wang; Nanan Gao; Xiaoping Mao; Lin Jia (Natural Resources Research, 2022)

Calcium/calmodulin-dependent protein kinase IV regulates vascular autophagy and insulin signaling through Akt/mTOR/CREB pathway in ob/ob mice - Jiali Liu; Yue Li; Ning Gao; Jing Ji; Qian He (Journal of Physiology and Biochemistry, 2022)

Inter-decadal variability of the heat source over the Tibetan Plateau - Jingchen Liu; Xiaodan Guan; Zhaokui Gao; Xiaoqian Huang; Jieru Ma; Yongli He; Tiejun Xie (Climate Dynamics, 2022)

Bayesian maximum entropy interpolation of sea surface temperature data: A comparative assessment - Zekun Gao; Yutong Jiang; Junyu He; Jiaping Wu; George Christakos (International Journal of Remote Sensing, 2022)

The evaluation of rock brittleness and its application: a review study - Yingjie Xia; Hui Zhou; Chuanqing Zhang; Shihai He; Yang Gao; Peng Wang (European Journal of Environmental and Civil Engineering, 2022)

Aconitine linoleate, a natural lipo-diterpenoid alkaloid, stimulates anti-proliferative activity reversing doxorubicin resistance in MCF-7/ADR breast cancer cells as a selective topoisomerase IIα inhibitor - Shangxian Luan; Yingying Gao; Xiaoxia Liang; Li Zhang; Qiang Wu; Yunkai Hu; Lizi Yin; Changliang He; Shixi Liu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2022)

Bacterial community composition in gut content and ambient sediment of two tropical wild sea cucumbers (Holothuria atra and H. leucospilota) - Fei Gao; Yue Zhang; Peilin Wu; Mengling Chen; Linwen He; Qiang Xu; Aimin Wang (Journal of Oceanology and Limnology, 2022)

Effects of Gentiopicroside on activation of NLRP3 inflammasome in acute gouty arthritis mice induced by MSU - Menglin He; Cheng Hu; Meijuan Chen; Qian Gao; Liqiu Li; Weiqian Tian (Journal of Natural Medicines, 2022)
Acute gouty arthritis is a self-limiting inflammatory disease resulting from the deposition of monosodium urate (MSU) crystals. It has been shown that Gentiopicroside (GPS) possesses anti-inflammatory and analgesic functions. The aim of this study was to parse out whether GPS has an effect on acute gouty arthritis. We established an acute gouty arthritis model by the injection of MSU into the paw, and found that GPS relieves MSU-induced mechanical, thermal hyperalgesia, and paw swelling. Furthermore, GPS down-regulated the release of pro-inflammatory cytokines in paw tissues, including IL-1β, IL-6, IL-18, and TNF-α. The results of H&E staining and MPO activity measurement showed that GPS inhibits neutrophil infiltration. And the over-expressions of NOD-like receptor protein 3 (NLRP3), apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), and Caspase-1 induced by MSU were inhibited by treatment with GPS. These results revealed that GPS can treat acute gouty arthritis based on anti-inflammatory and analgesic properties in vivo, which might be ascribed to the inhibition on NLRP3 inflammasome. Furthermore, we performed in vitro study to confirm the results of in vivo study. Consistently, the results proved that GPS could inhibit the activation of NLRP3 inflammasome in RAW264.7 macrophages stimulated by LPS-MSU. In conclusion, this study provides an experimental basis for the application of GPS and expands the potential value of GPS in the therapy of acute gouty arthritis.

Vangl2 participates in the primary ciliary assembly under low fluid shear stress in hUVECs - Xin Sheng; Shuanglin Gao; Yan Sheng; Xiadan Xie; Junhua Wang; Yan He (Cell and Tissue Research, 2022)

Isolation and partial characterization of a novel bacteriocin from Pseudomonas azotoformans with antimicrobial activity against Pasterella multocida - Yu Wang; Shuang Lei; Inam Muhammad; Yu Jia; Cheng-guang He; Yi-Ming Wang; Yun-Hang Gao; Ling-Cong Kong; Hong-Xia Ma (Archives of Microbiology, 2022)

Effects of heavy metals on bacterial community structures in two lead–zinc tailings situated in northwestern China - Haijuan Li; Yuanyuan Shen; Yueqing He; Tianpeng Gao; Guangwen Li; Mingbo Zuo; Jing Ji; Changming Li; Xiangkai Li; Yueli Chen; Zhuoxin Yin; Xiaoxiao Li (Archives of Microbiology, 2022)

Ocean Response to a Climate Change Heat-Flux Perturbation in an Ocean Model and Its Corresponding Coupled Model - Jiangbo Jin; Xiao Dong; Juanxiong He; Yi Yu; Hailong Liu; Minghua Zhang; Qingcun Zeng; He Zhang; Xin Gao; Guangqing Zhou; Yaqi Wang (Advances in Atmospheric Sciences, 2022)

Recent advances in tissue stem cells - Xin Fu; Qiang He; Yu Tao; Mengdi Wang; Wei Wang; Yalong Wang; Qing Cissy Yu; Fang Zhang; Xiaoyu Zhang; Ye-Guang Chen; Dong Gao; Ping Hu; et al. (Science China Life Sciences, 2021)

Overexpression of UDP-glycosyltransferase genes enhanced aluminum tolerance through disrupting cell wall polysaccharide components in soybean - Zhengbiao Wang; He Li; Zhanpeng Wei; Haoran Sun; Ying He; Jie Gao; Zhenming Yang; Jiangfeng You (Plant and Soil, 2021)

Effects of biochar on the growth of Vallisneria natans in surface flow constructed wetland - Chaoqun Zheng; Xuanwen Zhang; Lin Gan; Zhaofang He; Jinling Zhu; Wen Zhang; Yan Gao; Liuyan Yang (Environmental Science and Pollution Research, 2021)

Compound heterozygous DCLRE1C mutations lead to clinically typical Severe Combined Immunodeficiency presenting with Graft Versus Host Disease - Wenjun Mou; Liwei Gao; Jianxin He; Ju Yin; Baoping Xu; Jingang Gui (Immunogenetics, 2021)

A novel investigation on casing deformation during hydraulic fracturing in the Weirong shale gas field, Sichuan basin, China - Ze Li; Gao Li; Hongtao Li; Hao Yu; Long He; Zujun Jiang (Arabian Journal of Geosciences, 2021)

Coexistence of Candida albicans and Enterococcus faecalis increases biofilm virulence and periapical lesions in rats - Qian Du; Shasha Yuan; Shuangyuan Zhao; Di Fu; Yifei Chen; Yuan Zhou; Yangpei Cao; Yuan Gao; Xin Xu; Xuedong Zhou; Jinzhi He (Biofouling, 2021)

Cloning and identification of a new repressor of 3,17β-Hydroxysteroid dehydrogenase of Comamonas testosteroni - Weiqi Xie; Qin Xia; Ling Chen; Guangming Xiong; Yuwei Gao; Yuanhua Yu; Xiuxia He (Molecular Biology Reports, 2021)

Application of nanomaterials decorated with cyclodextrins as sensing elements for environment analysis - Lingfeng Gao; Chiyang He (Environmental Science and Pollution Research, 2021)

Contributors to linkage between Arctic warming and East Asian winter climate - Xinping Xu; Shengping He; Yongqi Gao; Botao Zhou; Huijun Wang (Climate Dynamics, 2021)
Previous modelling and observational studies have shown discrepancies in the interannual relationship of winter surface air temperature (SAT) between Arctic and East Asia, stimulating the debate about whether Arctic change can influence midlatitude climate. This study uses two sets of coordinated experiments (EXP1 and EXP2) from six different atmospheric general circulation models. Both EXP1 and EXP2 consist of 130 ensemble members, each of which in EXP1 (EXP2) was forced by the same observed daily varying sea ice and daily varying (daily climatological) sea surface temperature (SST) for 1982–2014 but with different atmospheric initial conditions. Large spread exists among ensemble members in simulating the Arctic–East Asian SAT relationship. Only a fraction of ensemble members can reproduce the observed deep Arctic warming–cold continent pattern which extends from surface to upper troposphere, implying the important role of atmospheric internal variability. The mechanisms of deep Arctic warming and shallow Arctic warming are further distinguished. Arctic warming aloft is caused primarily by poleward moisture transport, which in conjunction with the surface warming coupled with sea ice melting constitutes the surface-amplified deep Arctic warming throughout the troposphere. These processes associated with the deep Arctic warming may be related to the forcing of remote SST when there is favorable atmospheric circulation such as Rossby wave train propagating from the North Atlantic into the Arctic.

Carbon limitation overrides acidification in mediating soil microbial activity to nitrogen enrichment in a temperate grassland - Qiushi Ning; Stephan Hättenschwiler; Xiaotao Lü; Paul Kardol; Yunhai Zhang; Cunzheng Wei; Chengyuan Xu; Jianhui Huang; Ang Li; Junjie Yang; Jing Wang; Yang Peng; et al. (Global Change Biology, 2021)
Higher ecosystem nitrogen (N) inputs resulting from human activities often suppress soil microbial biomass and respiration, thereby altering biogeochemical cycling. Soil acidification and carbon (C) limitation may drive these microbial responses, yet their relative importance remains elusive, which limits our understanding of the longer term effects of increasing N inputs. In a field experiment with continuous N addition at seven different rates from 0 to 50 g N m −2 year −1 over 6 years in a temperate grassland of Inner Mongolia, China, we examined the responses of soil microbial biomass and respiration to changes in soil acidity and C availability by adding lime and/or glucose to soil samples. Soil microbial biomass and respiration did only weakly respond to increasing soil pH, but increased strongly in response to higher C availability with increasing N addition rates. Soil net N immobilization increased in response to glucose addition, and soil microbial biomass increased at higher rates than microbial respiration along the gradient of previous N addition rates, both suggesting increasingly reinforced microbial C limitation with increasing N addition. Our results provide clear evidence for strong N‐induced microbial C limitation, but only little support for soil acidity effects within the initial pH range of 4.73–7.86 covered by our study. Field data support this conclusion by showing reduced plant C allocation belowground in response to N addition, resulting in soil microbial C starvation over the long term. In conclusion, soil microbial biomass and respiration under N addition were strongly dependent on C availability, most likely originating from plant belowground C inputs, and was much less affected by changes in soil pH. Our data help clarify a long‐standing debate about how increasing N input rates affect soil microbial biomass and respiration, and improve the mechanistic understanding of the linkages between ecosystem N enrichment and C cycling.

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Phylogeny and subcellular localization analyses reveal distinctions in monocot and eudicot class IV acyl-CoA-binding proteins - Xue Jiang; Lijian Xu; Ying Gao; Mingliang He; Qingyun Bu; Wei Meng (Planta, 2021)

Activation of the Hippocampal LXRβ Improves Sleep-Deprived Cognitive Impairment by Inhibiting Neuroinflammation - Chen Qiu; Min Wang; Wen Yu; Zheng Rong; He-Sheng Zheng; Ting Sun; Shui-Bing Liu; Ming-Gao Zhao; Yu-Mei Wu (Molecular Neurobiology, 2021)

BDS-3 SAR service and initial performance - Gang Li; Shuren Guo; Zehua He; Ya Gao; Wenxuan Li (GPS Solutions, 2021)

Interactive effects of nutrient availability, fluctuating supply, and plant parasitism on the post-invasion success of Bidens pilosa - Fang-Lei Gao; Qiao-Sheng He; Ru-Qian Xie; Jia-Hui Hou; Chen-Lu Shi; Jun-Min Li; Fei-Hai Yu (Biological Invasions, 2021)

Gelidibacter maritimus sp. nov., isolated from marine sediment - Cheng Gao; He-Yuan Lun; Dan-Dan Shang; Min Cai; Meng-Qi Ye; Zong-Jun Du (Archives of Microbiology, 2021)

Prediction of InSAR deformation time-series using a long short-term memory neural network - Yi Chen; Yi He; Lifeng Zhang; Youdong Chen; Hongyu Pu; Baoshan Chen; Liya Gao (International Journal of Remote Sensing, 2021)

Numerical Study on the Hydrodynamic Characteristics of a Double-Row Floating Breakwater Composed of a Pontoon and an Airbag - Xiaofei Cheng; Chang Liu; Qilong Zhang; Ming He; Xifeng Gao (Journal of Marine Science and Engineering, 2021)
By adding a cylindrical airbag on the leeward side of a cuboid pontoon, a new-type double-row floating breakwater is designed to improve the wave attenuation performance, and its hydrodynamic characteristics are studied through numerical simulations. First, based on the smoothed particle hydrodynamics (SPH) method, a numerical model used to simulate the interaction between waves and moored floating bodies is built. The fluid motion is governed by the Navier–Stokes equations. The motion of the floating body is computed according to Newton’s second law. The modified dynamic boundary condition is employed to treat the solid boundary. The lumped-mass method is adopted to implement the mooring system. Then, two physical model experiments on waves interaction with cuboid and dual cylindrical floating pontoons are reproduced. By comparing the experimental and numerical wave transmission coefficients, wave reflection coefficients, response amplitude operators and mooring force, the reliability of the numerical model is validated. Finally, the validated numerical model is applied to study the influence of separation distance and wave parameters on the hydrodynamic characteristics of the double-row floating breakwater. The results indicate that the optimal separation distance between pontoon and airbag is 0.75 times the wavelength. At such separation distance and within the concerned 1–4 m wave heights and 4–7 s wave periods, the pontoon-airbag system presents better wave attenuation performance than a single pontoon. This improvement weakens as wave height increases while it strengthens as the wave period increases. In addition, the double-row floating breakwater is more effective in a high-wave regime than in a low-wave regime. In the case of short waves, attention should be paid to the stability and mooring reliability of the seaward pontoon, while in the case of long waves, care needs to be taken of the leeward airbag.

The Variations of Bacterial Community Structures in Tailing Soils Suffering from Heavy Metal Contaminations - Tianpeng Gao; Haijuan Li; Yueqing He; Yuanyuan Shen; Guangwen Li; Xiangkai Li; Yueli Chen; Yubing Liu; Changming Li; Jing Ji; Jing Xu; Guohua Chang (Water, Air, & Soil Pollution, 2021)

Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica) - Hui Zhi; Qiang He; Sha Tang; Junjun Yang; Wei Zhang; Huifang Liu; Yanchao Jia; Guanqing Jia; Aiying Zhang; Yuhui Li; Erhu Guo; Ming Gao; et al. (Theoretical and Applied Genetics, 2021)

On the Mechanism of High-Voltage Pulsed Fragmentation from Electrical Breakdown Process - Xiaohua Zhu; Yunxu Luo; Weiji Liu; Ling He; Rui Gao; Yudan Jia (Rock Mechanics and Rock Engineering, 2021)

Bi-parametric magnetic resonance imaging based radiomics for the identification of benign and malignant prostate lesions: cross-vendor validation - Xuefu Ji; Jiayi Zhang; Wei Shi; Dong He; Jie Bao; Xuedong Wei; Yuhua Huang; Yangchuan Liu; Jyh-Cheng Chen; Xin Gao; Yuguo Tang; Wei Xia (Physical and Engineering Sciences in Medicine, 2021)

Hyaluronan synthase 2 (HAS2) regulates cell phenotype and invadopodia formation in luminal-like breast cancer cells - Yumeng Sheng; Manlin Cao; Yiwen Liu; Yiqing He; Guoliang Zhang; Yan Du; Feng Gao; Cuixia Yang (Molecular and Cellular Biochemistry, 2021)

TUPDB: Target-Unrelated Peptide Data Bank - Bifang He; Shanshan Yang; Jinjin Long; Xue Chen; Qianyue Zhang; Hui Gao; Heng Chen; Jian Huang (Interdisciplinary Sciences: Computational Life Sciences, 2021)

Exosomal long non-coding RNA SOX2 overlapping transcript enhances the resistance to EGFR-TKIs in non-small cell lung cancer cell line H1975 - Dongbo Zhou; Zhi Xia; Mingxuan Xie; Ying Gao; Qiao Yu; Baimei He (Human Cell, 2021)

Detailed dynamics analysis of net nitrate uptake by wheat roots after sucrose signal molecule treatment - Jinzhi Li; Bin He; Bihua Zhu; Xiaoyan Wang; Jianming Gao (Brazilian Journal of Botany, 2021)

Copper and zinc isotope variations in ferromanganese crusts and their isotopic fractionation mechanism - Lianhua He; Jihua Liu; Hui Zhang; Jingjing Gao; Aimei Zhu; Ying Zhang (Acta Oceanologica Sinica, 2021)

Ethylene‐regulated leaf lifespan explains divergent responses of plant productivity to warming among three hydrologically different growing seasons - Haiyan Ren; Guodong Han; Mai‐He Li; Cuiping Gao; Lin Jiang (Global Change Biology, 2021)
Leaf senescence is known to be regulated by the plant hormone ethylene, but how leaf lifespan responds to global environmental change and links to ecosystem‐level responses remains largely unexplored. Here we investigated the effects of climate warming and nitrogen addition on plant functional traits, plant hormone ethylene and net primary production in a 13‐year field experiment in a desert steppe. Across the last 3 years of the experiment (2016–2018), plant productivity increased under warming only in 2016, when there was above normal precipitation, but consistently increased with nitrogen addition. Warming enhanced net photosynthesis, leaf nitrogen and ethylene production and reduced leaf lifespan in 2016 (a wet year), but not in 2017 (a drought year); the effect of warming in 2018 (a year with normal precipitation) was opposite to 2016, likely due to the below‐normal precipitation in the mid‐growing season in 2018. Nitrogen addition led to increases in leaf nitrogen, ethylene production and net photosynthesis, and declines in leaf lifespan in 2016 and 2018, but not in 2017. The ethylene‐regulated lifespan was further evidenced by the addition of CoCl 2 (an ethylene biosynthesis inhibitor) that reduced ethylene production and prolonged lifespan. Structural equation modeling showed that leaf lifespan had a negative effect on plant productivity, both directly and indirectly via its negative effect on net photosynthesis, across all 3 years. Our results demonstrate the divergent responses of leaf lifespan and, in turn, plant productivity to warming under inter‐annual and intra‐annual precipitation variation, thus linking plant hormone production, functional traits and ecosystem functioning in the face of global environmental change.

Elevated pCO2 Impedes Succession of Phytoplankton Community From Diatoms to Dinoflagellates Along With Increased Abundance of Viruses and Bacteria - Ruiping Huang; Jiazhen Sun; Yunlan Yang; Xiaowen Jiang; Zhen Wang; Xue Song; Tifeng Wang; Di Zhang; He Li; Xiangqi Yi; Shouchang Chen; Nanou Bao; et al. (Frontiers in Marine Science, 2021)
Eutrophic coastal regions are highly productive and greatly influenced by human activities. Primary production supporting the coastal ecosystems is supposed to be affected by progressive ocean acidification driven by increasing CO 2 emissions. In order to investigate the effects of high p CO 2 (HC) on eutrophic plankton community structure and ecological functions, we employed 9 mesocosms and carried out an experiment under ambient (∼410 ppmv) and future high (1000 ppmv) atmospheric p CO 2 conditions, using in situ plankton community in Wuyuan Bay, East China Sea. Our results showed that HC along with natural seawater temperature rise significantly boosted biomass of diatoms with decreased abundance of dinoflagellates in the late stage of the experiment, demonstrating that HC repressed the succession from diatoms to dinoflagellates, a phenomenon observed during algal blooms in the East China Sea. HC did not significantly influence the primary production or biogenic silica contents of the phytoplankton assemblages. However, the HC treatments increased the abundance of viruses and heterotrophic bacteria, reflecting a refueling of nutrients for phytoplankton growth from virus-mediated cell lysis and bacterial degradation of organic matters. Conclusively, our results suggest that increasing CO 2 concentrations can modulate plankton structure including the succession of phytoplankton community and the abundance of viruses and bacteria in eutrophic coastal waters, which may lead to altered biogeochemical cycles of carbon and nutrients.

Antitubercular metabolites from the marine-derived fungus strain Aspergillus fumigatus MF029 - Zhijun Song; Yu Liu; Jieyu Gao; Jiansen Hu; Hongtao He; Shengwang Dai; Luoqiang Wang; Huanqin Dai; Lixin Zhang; Fuhang Song (Natural Product Research, 2021)

Contributions of climate change and human activities to runoff and sediment discharge reductions in the Jialing River, a main tributary of the upper Yangtze River, China - Yiting Shao; Yi He; Xingmin Mu; Guangju Zhao; Peng Gao; Wenyi Sun (Theoretical and Applied Climatology, 2021)

Oxiracetam Mediates Neuroprotection Through the Regulation of Microglia Under Hypoxia-Ischemia Neonatal Brain Injury in Mice - Dan Wang; Yanbang Wei; Jingxia Tian; Dong He; Rui Zhang; Xiaoshuai Ji; Xiaoming Huang; Jun Sun; Jiajia Gao; Zixiao Wang; Qi Pang; Qian Liu (Molecular Neurobiology, 2021)

Exposure to butylated hydroxytoluene compromises endometrial decidualization during early pregnancy - Zhifang Sun; Rufei Gao; Xuemei Chen; Xueqing Liu; Yubin Ding; Yanqing Geng; Xinyi Mu; Taihang Liu; Fangfang Li; Yingxiong Wang; Junlin He (Environmental Science and Pollution Research, 2021)

Preparation, characterization, and catalytic activity of a novel MgO/expanded graphite for ozonation of Cu-EDTA - Jun He; Wenchao Song; Xiaohan Huang; Zuoyu Gao (Environmental Science and Pollution Research, 2021)

Gelidibacter pelagius sp. nov., Isolated from Coastal Sediment - He-Yuan Lun; Cheng Gao; Dan-Dan Shang; Ya Gong; Zong-Jun Du (Current Microbiology, 2021)

Potential Transforming Pathway of Arsenic Species Mediated by Iron- and Sulfate-Reducing Bacteria During Ice-Bound Period - Wenjing Shi; Wenjie Song; Manshu Gao; Hao Li; Haoji Wang; Changwei Lü; Jiang He (Water, Air, & Soil Pollution, 2021)

Structural, Functional, and Molecular Imaging of Autism Spectrum Disorder - Xiaoyi Li; Kai Zhang; Xiao He; Jinyun Zhou; Chentao Jin; Lesang Shen; Yuanxue Gao; Mei Tian; Hong Zhang (Neuroscience Bulletin, 2021)

Successful treatment of refractory pure red cell aplasia with eltrombopag after ABO-incompatible allogeneic hematopoietic stem cell transplantation - Yang Gao; Fei Gao; Jimin Shi; Huarui Fu; He Huang; Yanmin Zhao (Journal of Zhejiang University-SCIENCE B, 2021)

Fluorescence characteristics of dissolved organic matter in several independent water bodies: possible sources and land-use effects - Qiang He; Li Gao; Zilin Wang; Yuanjiang Tang; Baozhu Pan; Ming Li (Environmental Science and Pollution Research, 2021)

Feasibility of easy-to-implement methods to analyze systematic errors of multipath, differential code bias, and inter-system bias for low-cost receivers - Zhetao Zhang; Haijun Yuan; Bofeng Li; Xiufeng He; Shuzhao Gao (GPS Solutions, 2021)

Heavy Metals in Indoor Dust Across China: Occurrence, Sources and Health Risk Assessment - Baolin Liu; Fei Huang; Yong Yu; Xuedong Li; Yaowei He; Lei Gao; Xin Hu (Archives of Environmental Contamination and Toxicology, 2021)

Long‐term evolution of global sea surface temperature trend - Zhenhao Xu; Fei Ji; Bo Liu; Taichen Feng; Yuan Gao; Yongli He; Fei Chang (International Journal of Climatology, 2021)
The ocean plays an essential role in regulating global and regional climate, which is mainly achieved through sea surface temperature anomaly (SSTA) changes. Studies on global sea surface temperature (GSST) are primarily carried out under linear assumption, which is not capable of fully revealing the evolution characteristics of sea surface temperature (SST) due to the non‐linear and non‐stationary nature of the SST. Here, the evolution of the GSST trend in the past century is investigated by using an adaptive and local spatial–temporally multidimensional ensemble empirical mode decomposition method. The results show that the global ocean has been warming except for the subpolar North Atlantic, the equatorial central Pacific, and the Southern Ocean in the Pacific sector. The equatorial central Pacific turned from cooling to warming around the middle of the last century made it one of the fastest‐warming regions in recent decades with other regions located in the Arctic Ocean and the western‐boundary current regions and their mid‐latitude extensions in both hemispheres. The strongest warming during recent decades is found in the Arctic Ocean, east of the continents in the northern hemisphere, the entire Indian Ocean, and especially in the tropical Pacific Ocean. From a zonal average perspective, warming (>0.1 K since 1900) first took place in the subtropical regions of the Northern Hemisphere and 50°S of the Southern Hemisphere almost simultaneously around 1910, then followed by the subpolar warming in the Northern Hemisphere. The first two bands of warming both expanded equatorward leading to the fast warming of tropical oceans, especially for the Pacific Ocean.

Genotypic variation in nitrogen utilization efficiency in oilseed rape is related to the coordination of leaf senescence and root N uptake during reproductive stage - Huiying He; Yuyu Xie; Anyu Zhao; Wencong Hu; Xiao Guo; Anthony J. Miller; Xiaoming Wu; Biyun Chen; Rong Zhang; Hui Tian; Yajun Gao (Plant and Soil, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Mapping Domain- and Age-Specific Functional Brain Activity for Children’s Cognitive and Affective Development - Lei Hao; Lei Li; Menglu Chen; Jiahua Xu; Min Jiang; Yanpei Wang; Linhua Jiang; Xu Chen; Jiang Qiu; Shuping Tan; Jia-Hong Gao; Yong He; et al. (Neuroscience Bulletin, 2021)

3D Multi-scale Reconstruction of Fractured Shale and Influence of Fracture Morphology on Shale Gas Flow - Peng Hou; Xin Liang; Yun Zhang; Jian He; Feng Gao; Jia Liu (Natural Resources Research, 2021)

Effect of ambient air pollution on tuberculosis risks and mortality in Shandong, China: a multi-city modeling study of the short- and long-term effects of pollutants - Yao Liu; Shi Zhao; Yifan Li; Wanmei Song; Cuixiang Yu; Lei Gao; Jinjun Ran; Daihai He; Huaichen Li (Environmental Science and Pollution Research, 2021)

Chemical Characteristics of Flow Driven by Rainfall and Associated Impacts on Shallow Groundwater Quality in a Karst Watershed, Southwest China - Zhuo Hao; Yang Gao; Sophie M. Green; Xuefa Wen; Jun Yang; Bailian Xiong; Timothy A. Quine; Nianpeng He (Environmental Processes, 2021)

Efficiency comparison of B6(Cg)-Tyrc−2j /J and C57BL/6NTac embryos as hosts for the generation of knockout mice - Yu’e Ma; Lei He; Lijie Xiang; Jie Zhang; Jing Wang; Wenjing Zhu; Wenni Cao; Yichen Zhu; Man Gao; Fei Zhou; Zhiwei Liu (Transgenic Research, 2021)
Careful selection of the host embryo is critical to the efficient production of knockout (KO) mice when injecting mouse embryonic stem (mES) cells into blastocysts. B6(Cg)-Tyr c−2j /J (B6 albino) and C57BL/6NTac (B6NTac) strains of mice are widely used to produce host blastocysts for such procedures. Here, we tested these two strains to identify an appropriate match for modified agouti C57BL/6N (JM8A3.N1) mES cells. When comparing blastocyst yield, super-ovulated B6NTac mice produced more injectable blastocysts per female than B6 albino mice (8.2 vs. 5.4). There was no significant difference in birth rate when injected embryos were transferred to the same pseudopregnant recipient strain. However, the live birth rate was significantly higher for B6NTac blastocysts than B6 albino blastocysts (62.7% vs. 50.2%). In addition, the proportion of pups exhibiting high-level and complete chimerism, as identified by coat color, was also significantly higher in the B6NTac strain. There was no obvious difference in the efficiency of germline transmission (GLT) when compared between B6NTac and B6 albino host embryos (61.5% vs. 63.3% for mES clones; 64.5% vs. 67.9% for genes, respectively), thus suggesting that an equivalent GLT rate could be obtained with only a few blastocyst injections for B6NTac embryos. In conclusion, our data indicate that B6NTac blastocysts are a better choice for the microinjection of JM8A3.N1 mES cells than B6 albino blastocysts.

Experimental investigation of dry density, initial moisture content, and temperature for granite residual soil disintegration - Xiaoyan Luo; He Gao; Pei He; Weiping Liu (Arabian Journal of Geosciences, 2021)

Spatial and environmental factors contributing to phytoplankton biogeography and biodiversity in mountain ponds across a large geographic area - Chao Chang; Li Gao; Jing Wei; Ning Ma; Qiang He; Baozhu Pan; Ming Li (Aquatic Ecology, 2021)

Interactions Between Ultraviolet B Radiation, Warming, and Changing Nitrogen Source May Reduce the Accumulation of Toxic Pseudo-nitzschia multiseries Biomass in Future Coastal Oceans - Kyla J. Kelly; Fei-Xue Fu; Xiaowen Jiang; He Li; Dong Xu; Nina Yang; Michelle A. DeMers; Joshua D. Kling; Kunshan Gao; Naihao Ye; David A. Hutchins (Frontiers in Marine Science, 2021)
Understanding the environmental conditions that trigger Pseudo-nitzschia bloom formation and domoic acid (DA) production is critical as the frequency and severity of these toxic blooms increases in the face of anthropogenic change. However, predicting the formation of these harmful blooms in a future ocean remains a challenge. Previous studies have examined the effects of single environmental drivers on Pseudo-nitzschia spp. growth and toxin production, but few have considered the interactions between them. In this multiple driver study with Pseudo-nitzschia multiseries , we used a full factorial matrix experimental design to examine the simultaneous effects of temperature (20 and 25°C), nitrogen source (nitrate and urea), and irradiance (photosynthetically active radiation with and without ultraviolet B radiation; UVB). This strain of P. multiseries was unable to withstand prolonged exposures (>0.5 h) to 0.06 mw⋅cm –2 UVB light, with implications for near-surface bloom formation if future shallower mixed layers increase UVB exposure. Growth rates were inhibited by UVB, but photosynthesis and carbon fixation continued at a reduced capacity. Additionally, DA synthesis continued despite UVB-induced growth inhibition. Warming by 5°C enhanced cellular DA quotas three-fold. Within these warmer treatments, urea-grown cultures exposed to UVB had the highest amount of DA per cell, suggesting that interactive effects between UVB exposure, warming, and urea can synergistically enhance toxin production. However, overall production of toxic biomass was low, as growth-integrated DA production rates were near zero. This indicates that although Pseudo-nitzschia multiseries cell-specific toxicity could worsen in an anthropogenically-altered future ocean, bloom formation may be inhibited by increased exposure to UVB. This multi-variable experimental approach revealed previously unknown interactions that could not have been predicted based on combined effects of single-variable experiments. Although P. multiseries DA production may be enhanced in a future ocean, inherent sensitivity to prolonged UVB exposure may moderate trophic transfer of toxin to coastal food webs.

Comparison of picoeukaryote community structures and their environmental relationships between summer and autumn in the southern Chukchi Sea - Fang Zhang; Jianfeng He; Haiyan Jin; Qiang Hao; Zhongyong Gao; Heng Sun (Extremophiles, 2021)

Identification and expression analysis of the Hevea brasiliensis phosphate transporter 1 gene family - Yong Sun; Le Gao; Dan Wang; Bingsun Wu; Zheng Tong; Min Wu; Guihua Wang; Wenguan Wu; Jiashao Wei; Renjun Feng; Peng He (Trees, 2021)

Post-flowering nitrogen uptake leads to the genotypic variation in seed nitrogen accumulation of oilseed rape - Xiao Guo; Yunyou Nan; Huiying He; Bao-Luo Ma; Neil B. McLaughlin; Xiaoming Wu; Biyun Chen; Yajun Gao (Plant and Soil, 2021)

Dietary berberine can ameliorate glucose metabolism disorder of Megalobrama amblycephala exposed to a high-carbohydrate diet - Chang He; Xiaoyan Jia; Li Zhang; Fan Gao; Weibo Jiang; Chuang Wen; Cheng Chi; Xiangfei Li; Guangzhen Jiang; Haifeng Mi; Wenbin Liu; Dingdong Zhang (Fish Physiology and Biochemistry, 2021)

Dissipation kinetics and safety evaluation of pyraclostrobin and its desmethoxy metabolite BF 500-3 in a cucumber greenhouse agroecosystem - Lifei He; Falin He; Song Yang; Yangyang Gao; Beixing Li; Feng Liu; Wei Mu (Environmental Science and Pollution Research, 2021)

Dynamic relationship between meteorological conditions and air pollutants based on a mixed Copula model - Simin He; Zhiyao Li; Wenjie Wang; Mingxing Yu; Liangpo Liu; Md Nur Alam; Qian Gao; Tong Wang (International Journal of Climatology, 2021)
Many methods have been developed to verify the correlation between meteorological conditions and air pollutants; however, all have limitations that lead to biased or incomplete conclusions. Hence, improved methods are urgently required to describe this correlation comprehensively and accurately. In this study, we demonstrated the ability of the Copula function to apply time‐varying correlations between meteorological factors and atmospheric pollutants. A mixed Copula model was constructed using meteorological monitoring data for Beijing and Guangzhou from 2014 to 2019 to dynamically analyse the correlation characteristics and tail dependence between these factors. We then performed a correlation analysis for the data from the average, lower, and upper tails to obtain a more accurate and comprehensive correlation description. Dynamic analysis results demonstrated significant seasonal fluctuations between meteorological conditions and pollutants relationships. Moreover, the correlation coefficient variations differ according to their average and tail values. High humidity is more likely to be accompanied by increased NO 2 compared with average summer humidity. Our proposed model represents a novel application of the Copula function for determining the factors influencing air pollution. This model emphasizes the tail dependence between meteorological conditions and air pollutant concentrations and can be used to guide more targeted prevention and control strategies.

Seismic wave equations in tight oil/gas sandstone media - Jinghuai Gao; Weimin Han; Yanbin He; Haixia Zhao; Hui Li; Yijie Zhang; Zongben Xu (Science China Earth Sciences, 2021)

Uncertainty, sensitivity analysis and optimization of a reservoir geological model - Hu Yong; He Wenxiang; Zhou Yanli; Guo Bincheng; Gao Zhaopu (Marine Georesources & Geotechnology, 2021)

Genome-scale revealing the central metabolic network of the fast growing methanotroph Methylomonas sp. ZR1 - Wei Guo; Yang Li; Ronglin He; Wuxi Chen; Feng Gao; Demao Li; Xiaoping Liao (World Journal of Microbiology and Biotechnology, 2021)

QTL mapping for foxtail millet plant height in multi-environment using an ultra-high density bin map - Qiang He; Hui Zhi; Sha Tang; Lu Xing; Suying Wang; Haigang Wang; Aiying Zhang; Yuhui Li; Ming Gao; Haijin Zhang; Guoqiu Chen; Shutao Dai; et al. (Theoretical and Applied Genetics, 2021)

Aristocratic human papillomavirus drove cervical cancer: a study of the therapeutic potential of the combination of interferon with zinc - Yun-He Gao; Lei Yu; Zhong-Shan Liu; Yun-Feng Li (Molecular and Cellular Biochemistry, 2021)

Spatial-temporal pattern evolution and driving force analysis of ecological environment vulnerability in Panzhihua City - Xiaoai Dai; Yu Gao; Xuwei He; Ting Liu; Bohan Jiang; Huaiyong Shao; Yuanzhi Yao (Environmental Science and Pollution Research, 2021)

CRISPR/Cas9-mediated genome editing in Penicillium oxalicum and Trichoderma reesei using 5S rRNA promoter-driven guide RNAs - Qi Wang; Qinqin Zhao; Qin Liu; Xin He; Yaohua Zhong; Yuqi Qin; Liwei Gao; Guodong Liu; Yinbo Qu (Biotechnology Letters, 2021)

Brainstem atrophy in the early stage of Alzheimer’s disease: a voxel-based morphometry study - Xiaoxi Ji; Hui Wang; Minwei Zhu; Yingjie He; Hong Zhang; Xiaoguang Chen; Wenpeng Gao; Yili Fu (Brain Imaging and Behavior, 2021)

CAS-ESM2.0 Model Datasets for the CMIP6 Flux-Anomaly-Forced Model Intercomparison Project (FAFMIP) - Jiangbo Jin; He Zhang; Xiao Dong; Hailong Liu; Minghua Zhang; Xin Gao; Juanxiong He; Zhaoyang Chai; Qingcun Zeng; Guangqing Zhou; Zhaohui Lin; Yi Yu; et al. (Advances in Atmospheric Sciences, 2021)
The second version of the Chinese Academy of Sciences Earth System Model (CAS-ESM2.0) is participating in the Flux-Anomaly-Forced Model Intercomparison Project (FAFMIP) experiments in phase 6 of the Coupled Model Intercomparison Project (CMIP6). The purpose of FAFMIP is to understand and reduce the uncertainty of ocean climate changes in response to increased CO 2 forcing in atmosphere-ocean general circulation models (AOGCMs), including the simulations of ocean heat content (OHC) change, ocean circulation change, and sea level rise due to thermal expansion. FAFMIP experiments (including faf-heat, faf-stress, faf-water, faf-all, faf-passiveheat, faf-heat-NA50pct and faf-heat-NA0ct) have been conducted. All of the experiments were integrated over a 70-year period and the corresponding data have been uploaded to the Earth System Grid Federation data server for CMIP6 users to download. This paper describes the experimental design and model datasets and evaluates the preliminary results of CAS-ESM2.0 simulations of ocean climate changes in the FAFMIP experiments. The simulations of the changes in global ocean temperature, Atlantic Meridional Overturning Circulation (AMOC), OHC., and dynamic sea level (DSL), are all reasonably reproduced.

CAS-ESM2.0 Model Datasets for the CMIP6 Ocean Model Intercomparison Project Phase 1 (OMIP1) - Xiao Dong; Jiangbo Jin; Hailong Liu; He Zhang; Minghua Zhang; Pengfei Lin; Qingcun Zeng; Guangqing Zhou; Yongqiang Yu; Mirong Song; Zhaohui Lin; Ruxu Lian; et al. (Advances in Atmospheric Sciences, 2021)
As a member of the Chinese modeling groups, the coupled ocean-ice component of the Chinese Academy of Sciences’ Earth System Model, version 2.0 (CAS-ESM2.0), is taking part in the Ocean Model Intercomparison Project Phase 1 (OMIP1) experiment of phase 6 of the Coupled Model Intercomparison Project (CMIP6). The simulation was conducted, and monthly outputs have been published on the ESGF (Earth System Grid Federation) data server. In this paper, the experimental dataset is introduced, and the preliminary performances of the ocean model in simulating the global ocean temperature, salinity, sea surface temperature, sea surface salinity, sea surface height, sea ice, and Atlantic Meridional Overturning Circulation (AMOC) are evaluated. The results show that the model is at quasi-equilibrium during the integration of 372 years, and performances of the model are reasonable compared with observations. This dataset is ready to be downloaded and used by the community in related research, e.g., multi-ocean-sea-ice model performance evaluation and interannual variation in oceans driven by prescribed atmospheric forcing.

Variations of soil organic matters and plant cuticular waxes along an altitude gradient in Qinghai-Tibet Plateau - Luhua Yao; Na Guo; Yuji He; Yu Xiao; Yang Li; Jianhua Gao; Yanjun Guo (Plant and Soil, 2021)

Studies on the effects of bone marrow stem cells on mitochondrial function and the alleviation of ARDS - Keji Zhang; Yuan Gao; Yuxiao Deng; Xiao Zhou; Changqing Zhu; Zhengyu He; Dan Lv (Molecular and Cellular Biochemistry, 2021)

MST1 modulates Th17 activation in psoriasis via regulating TLR4-NF-κB pathway - Huayang Tang; Ze Guo; Xianfa Tang; Jinping Gao; Wenjun Wang; He Huang; Xiaodong Zheng; Hui Cheng; Yujun Sheng; Liangdan Sun (Human Cell, 2021)

Synthesis and characterization of Ni-doped anatase TiO2 loaded on magnetic activated carbon for rapidly removing triphenylmethane dyes - Zhansheng Wu; Xiufang He; Zhenzhen Gao; Yongtao Xue; Xin Chen; Luohong Zhang (Environmental Science and Pollution Research, 2021)

Screening and identification of a specific peptide binding to breast cancer cells from a phage-displayed peptide library - Huijuan Jin; Xiaojie Gao; Li Xiao; Huimin He; Sinan Cheng; Caixia Zhang; Yifan Hou; Fengying Song; Xiaorong Su; Qian Gao; Zheng Lu; Ruina Yang; et al. (Biotechnology Letters, 2021)

An Experimental Model of Neurodegenerative Disease Based on Porcine Hemagglutinating Encephalomyelitis Virus–Related Lysosomal Abnormalities - Yungang Lan; Zi Li; Zhenzhen Wang; Xinran Wang; Gaili Wang; Jing Zhang; Shiyu Hu; Kui Zhao; Baofeng Xu; Feng Gao; Wenqi He (Molecular Neurobiology, 2020)

Assessing SARS-CoV-2 RNA levels and lymphocyte/T cell counts in COVID-19 patients revealed initial immune status as a major determinant of disease severity - Mingfeng Han; Mengyuan Xu; Yafei Zhang; Zhongping Liu; Shasha Li; Tengfei He; Jinsong Li; Yong Gao; Wanjun Liu; Tuantuan Li; Zixiang Chen; Xin Huang; et al. (Medical Microbiology and Immunology, 2020)

The Effects of Different Fluorescent Indicators in Observing the Changes of the Mitochondrial Membrane Potential during Oxidative Stress-Induced Mitochondrial Injury of Cardiac H9c2 Cells - Yahan Sun; Kunyan Zhou; Mali He; Ying Gao; Danjie Zhang; Yanwen Bai; Yuezhao Lai; Mengying Liu; Xuechao Han; Sen Xu; Wei Tian; Jingman Xu (Journal of Fluorescence, 2020)

Gene coexpression network analysis reveals the role of SRS genes in senescence leaf of maize (Zea mays L.) - Bing He; Pibiao Shi; Yuanda Lv; Zhiping Gao; Guoxiang Chen (Journal of Genetics, 2020)

Endoplasmic reticulum‐associated degradation mediated by MoHrd1 and MoDer1 is pivotal for appressorium development and pathogenicity of Magnaporthe oryzae - Wei Tang; Haolang Jiang; Osakina Aron; Min Wang; Xueyu Wang; Jiangfeng Chen; Birong Lin; Xuehang Chen; Qiaojia Zheng; Xiuqin Gao; Dou He; Airong Wang; et al. (Environmental Microbiology, 2020)
Summary Most secretory proteins are folded and modified in the endoplasmic reticulum (ER); however, protein folding is error‐prone, resulting in toxic protein aggregation and cause ER stress. Irreversibly misfolded proteins are subjected to ER‐associated degradation (ERAD), modified by ubiquitination, and degraded by the 26S proteasome. The yeast ERAD ubiquitin ligase Hrd1p and multispanning membrane protein Der1p are involved in ubiquitination and transportation of the folding‐defective proteins. Here, we performed functional characterization of MoHrd1 and MoDer1 and revealed that both of them are localized to the ER and are pivotal for ERAD substrate degradation and the ER stress response. MoHrd1 and MoDer1 are involved in hyphal growth, asexual reproduction, infection‐related morphogenesis, protein secretion and pathogenicity of M. oryzae . Importantly, MoHrd1 and MoDer1 mediated conidial autophagic cell death and subsequent septin ring assembly at the appressorium pore, leading to abnormal appressorium development and loss of pathogenicity. In addition, deletion of MoHrd1 and MoDer1 activated the basal unfolded protein response (UPR) and autophagy, suggesting that crosstalk between ERAD and two other closely related mechanisms in ER quality control system (UPR and autophagy) governs the ER stress response. Our study indicates the importance of ERAD function in fungal development and pathogenesis of M. oryzae .

Oceanic forcing of the global warming slowdown in multi‐model simulations - Xinping Xu; Shengping He; Tore Furevik; Yongqi Gao; Huijun Wang; Fei Li; Fumiaki Ogawa (International Journal of Climatology, 2020)
Concurrent with the slowdown of global warming during 2002–2013, the wintertime land surface air temperatures over Eurasia, North America, Africa, Australia, South America, and Greenland experienced notable cooling trends. The oceanic effects on the continental cooling trends are here investigated using two sets of uncoupled experiments with six different climate models. Daily and annually varying sea ice is prescribed for both sets of experiments, while daily and annually varying SST is used in the first set (EXP1) and daily and annually repeating climatological mean SST in the second set (EXP2). All six models capture the slowdown of global‐mean land surface air temperature during 2002–2013 winters in EXP1 only. The slowdown concurs with a negative phase of the Pacific Decadal Oscillation (PDO), indicating that PDO plays an important role in modulating the global warming signal. Not all ensemble members capture the cooling trends over the continents, suggesting additional contribution from internal atmospheric variability.

Activation of the bitter taste sensor TRPM5 prevents high salt-induced cardiovascular dysfunction - Hao Wu; Yuanting Cui; Chengkang He; Peng Gao; Qiang Li; Hexuan Zhang; Yanli Jiang; Yingru Hu; Xiao Wei; Zongshi Lu; Tianyi Ma; Daoyan Liu; et al. (Science China Life Sciences, 2020)

Influence of fracture surface roughness on local flow pattern: visualization using a microfluidic field experiment - Pingye Guo; Meng Wang; Kai Gao; Manchao He; Yanwei Wang (Hydrogeology Journal, 2020)

One new xanthenone from the marine-derived fungus Aspergillus versicolor MF160003 - Zhijun Song; Jieyu Gao; Jiansen Hu; Hongtao He; Pei Huang; Lixin Zhang; Fuhang Song (Natural Product Research, 2020)

A combination of linkage mapping and GWAS brings new elements on the genetic basis of yield-related traits in maize across multiple environments - Xiaoxiang Zhang; Zhongrong Guan; Zhaoling Li; Peng Liu; Langlang Ma; Yinchao Zhang; Lang Pan; Shijiang He; Yanling Zhang; Peng Li; Fei Ge; Chaoying Zou; et al. (Theoretical and Applied Genetics, 2020)

Study of failure mechanism of bottom-hole rock mass approaching a gas-fractured zone during nitrogen drilling - Luo Chengbo; Jiang Zujun; Li Gao; He Long; Ou Biao; Meng Yingfeng; Xiao Guoyi; Yan Yancheng; Wang Xiyong (Arabian Journal of Geosciences, 2020)

A shipborne experiment using a dual-antenna reflectometry system for GPS/BDS code delay measurements - Fan Gao; Tianhe Xu; Nazi Wang; Yunqiao He; Xiaowen Luo (Journal of Geodesy, 2020)

Parvibaculum sedimenti sp. nov., A Novel Soil Bacterium Isolated from Sediment - Yuxin Wang; Xiaomei Ye; Xiangping Kong; Yonglan Xi; Jing Du; Yan Zhu; Di Gao; Jian He (Current Microbiology, 2020)

Hydrodynamic characteristics of groundwater aquifer system under recharge and discharge conditions - Shu Wang; Zongjun Gao; Zhenyan Wang; Xi Wu; Yonghui An; Xiaohui Ren; Minghao He; Wenxiang Wang; Jiutan Liu (Arabian Journal of Geosciences, 2020)

Mechano-chemical coupling of irrigation enhances endodontic biofilm debridement - Jialei Xu; Yuan Gao; Yajun Meng; Weiwei Wu; Chialing Tsauo; Tingwei Guo; Yangpei Cao; Dingming Huang; Xuedong Zhou; Jinzhi He (Biofouling, 2020)

Transcripts and ABA-dependent signaling in response to drought stress in Hippophae rhamnoides L - Tong Zhang; Guori Gao; Juanjuan Liu; Guijuan Yang; Zhongrui Lv; Jianguo Zhang; Caiyun He (Trees, 2020)

Development and validation of high-throughput and low-cost STARP assays for genes underpinning economically important traits in wheat - Yuying Wu; Ming Li; Zhonghu He; Susanne Dreisigacker; Weie Wen; Hui Jin; Shengnan Zhai; Faji Li; Fengmei Gao; Jindong Liu; Rongge Wang; Pingzhi Zhang; et al. (Theoretical and Applied Genetics, 2020)

Transcriptomic variation of the flower–fruit transition in Physalis and Solanum - Huihui Gao; Jing Li; Li Wang; Jisi Zhang; Chaoying He (Planta, 2020)

Experimental study on freezing and thawing deformation of geogrid-reinforced silty clay structure - Rongfei Zhao; Shuning Zhang; Jin He; Wei Gao; Dan Jin; Liqun Xie (Bulletin of Engineering Geology and the Environment, 2020)

High throughput solid-phase screening of bacteria with cyclic amino alcohol deamination activity for enantioselective synthesis of chiral cyclic β-amino alcohols - Ya-Wen Chang; Jian-Dong Zhang; Xiao-Xiao Yang; Jing Li; Li-Li Gao; Shuang-Ping Huang; Xing-Mei Guo; Cao-Feng Zhang; Hong-Hong Chang; Jian-He Xu (Biotechnology Letters, 2020)

Effect of processing on the reduction of pesticide residues in a traditional Chinese medicine (TCM) - Hairong He; Fei Gao; Yonghong Zhang; Pengqiang Du; Weisheng Feng; Xiaoke Zheng (Food Additives & Contaminants: Part A, 2020)

Enhancement of Neuronal Activity in the Auditory Thalamus After Simulated Slow-Wave Oscillation - Lixia Gao; Yuanqing Zhang; Xinjian Li; Jufang He (Neuroscience Bulletin, 2020)

Plant height and its relationship with yield in wheat under different irrigation regime - Zhenxian Gao; Yanxia Wang; Guoying Tian; Yankun Zhao; Caihua Li; Qiao Cao; Ran Han; Zhanliang Shi; Mingqi He (Irrigation Science, 2020)

SNHG16 regulates invasion and migration of bladder cancer through induction of epithelial-to-mesenchymal transition - Wenwei Chen; Tao Jiang; Houping Mao; Rui Gao; Hua Zhang; Yanfeng He; Changyi Liu; Qin Chen (Human Cell, 2020)

Pollution characteristics and chronic health risk assessment of metals and metalloids in ambient PM2.5 in Licheng District, Jinan, China - Shaofeng Sui; Jack Ng; Yanxin Gao; Cheng Peng; Chang He; Guoling Wang; Zhiyan Liu (Environmental Geochemistry and Health, 2020)

Reliability and Individual Specificity of EEG Microstate Characteristics - Jiayi Liu; Jing Xu; Guangyuan Zou; Yong He; Qihong Zou; Jia-Hong Gao (Brain Topography, 2020)

Experimental study on the dynamic properties of lime-solidified soft soil under cyclic loading - Guijie Zhao; Huan Yan; Ying Yan; Shaobo Gao; Da Fan; Yang He; Yu Wang (Arabian Journal of Geosciences, 2020)

Hydrochemical and isotopic characteristics of groundwater in the Jiuquan East Basin, China - Xiaohui Ren; Zongjun Gao; Yonghui An; Jiutan Liu; Xi Wu; Minghao He; Jianguo Feng (Arabian Journal of Geosciences, 2020)

Preparation and Evaluation of Stearylamine-Bearing Pemetrexed Disodium-Loaded Cationic Liposomes In Vitro and In Vivo - Kongfang He; Jingjing Liu; Yan Gao; Yanyun Hao; Xuehua Yang; Guihua Huang (AAPS PharmSciTech, 2020)

Modeling leaf senescence of deciduous tree species in Europe - Qiang Liu; Shilong Piao; Matteo Campioli; Mengdi Gao; Yongshuo H. Fu; Kai Wang; Yue He; Xiangyi Li; Ivan A. Janssens (Global Change Biology, 2020)
Autumnal leaf senescence signals the end of photosynthetic activities in temperate deciduous trees and consequently exerts a strong control on various ecological processes. Predicting leaf senescence dates (LSD) with high accuracy is thus a prerequisite for better understanding the climate–ecosystem interactions. However, modeling LSD at large spatial and temporal scales is challenging. In this study, first, we used 19972 site‐year records (848 sites and four deciduous tree species) from the PAN European Phenology network to calibrate and evaluate six leaf senescence models during the period 1980–2013. Second, we extended the spatial analysis by repeating the procedure across Europe using satellite‐derived end of growing season and a forest map. Overall, we found that models that considered photoperiod and temperature interactions outperformed models using simple temperature or photoperiod thresholds for Betula pendula , Fagus sylvatica and Quercus robur . On the contrary, no model displayed reasonable predictions for Aesculus hippocastanum . This inter‐model comparison indicates that, contrary to expectation, photoperiod does not significantly modulate the accumulation of cooling degree days (CDD). On the other hand, considering the carryover effect of leaf unfolding date could promote the models’ predictability. The CDD models generally matched the observed LSD at species level and its interannual variation, but were limited in explaining the inter‐site variations, indicating that other environmental cues need to be considered in future model development. The discrepancies remaining between model simulations and observations highlight the need of manipulation studies to elucidate the mechanisms behind the leaf senescence process and to make current models more realistic.

The fungal mitochondrial membrane protein, BbOhmm, antagonistically controls hypoxia tolerance - Zhangjiang He; Xin Zhao; Yifei Gao; Nemat O. Keyhani; Huifang Wang; Juan Deng; Zhuoyue Lu; Yanze Kan; Zhibing Luo; Yongjun Zhang (Environmental Microbiology, 2020)
Summary Adaptation to low‐oxygen (LO) environment in host tissues is crucial for microbial pathogens, particularly fungi, to successfully infect target hosts. However, the underlying mechanisms responsible for hypoxia tolerance in most pathogens are poorly understood. A mitochondrial protein, BbOhmm, is demonstrated to limit oxidative stress resistance and virulence in the insect fungal pathogen, Beauveria bassiana . Here, we found that BbOhmm negatively affected hypoxic adaptation in the insect haemocoel while regulating respiration‐related events, heme synthesis and mitochondrial iron homeostasis. A homologue of the mammalian sterol regulatory element‐binding proteins (SREBPs), BbSre1, was shown to be involved in BbOhmm‐mediated LO adaptation. Inactivation of BbSre1 resulted in a significant increase in sensitivity to hypoxic and oxidative stress. Similar to ΔBbOhmm , ΔBbSre1 or the ΔBbOhmmΔBbSre1 double mutant accumulated high levels of heme and mitochondrial iron, regulating the similar pathways during hypoxic stress. BbSre1 transcriptional activity and nuclear import were repressed in ΔBbOhmm cells and affected by intracellular reactive oxygen species (ROS) and oxygen levels. These findings have led to a new model in which BbOhmm affects ROS homeostasis in combination with available oxygen to control the transcriptional activity of BbSre1, which in turn mediates LO adaptation by regulating mitochondrial iron homeostasis, heme synthesis and respiration‐implicated genes.

Characteristics and causes of the landslide on July 23, 2019 in Shuicheng, Guizhou Province, China - Siyuan Ma; Chong Xu; Xiwei Xu; Xiangli He; Haitao Qian; Qisong Jiao; Wei Gao; Huaining Yang; Yulong Cui; Pengfei Zhang; Kai Li; Hongrong Mo; et al. (Landslides, 2020)

Identification, association, and expression analysis of ZmNAC134 gene response to phosphorus deficiency tolerance traits in maize at seedling stage - Javed Hussain Sahito; Fei Zheng; Haitao Tang; Xuan He; Bowen Luo; Xiao Zhang; Peng Ma; Xin Ding; Dan Liu; Ling Wu; Shibin Gao (Euphytica, 2020)

Innovative health risk assessments of heavy metals based on bioaccessibility due to the consumption of traditional animal medicines - Tian-Tian Zuo; Hao-Ran Qu; Hong-Yu Jin; Lei Zhang; Fei-Ya Luo; Kun-Zi Yu; Fei Gao; Qi Wang; Lei Sun; Huai-Zhen He; Shuang-Cheng Ma (Environmental Science and Pollution Research, 2020)

Progress in watershed geography in the Yangtze River Basin and the affiliated ecological security perspective in the past 20 years, China - Yang Gao; Junjie Jia; Yao Lu; Xiaomin Sun; Xuefa Wen; Nianpeng He; Tiantian Yang (Journal of Geographical Sciences, 2020)

Influence of Aphis gossypii feeding on defense strategy of native and introduced populations of Ageratina adenophora - Ying Lin; Shu-Qi He; Zhi-Hui Lu; Yu-Lin Gao; Yan-Ru Duan; Zheng-Yue Li; Bin Chen; Fu-Rong Gui (Arthropod-Plant Interactions, 2020)

Formation of Nitrosodipropylamine from Nitrogenous Contaminants (Amines and Amine-Based Pesticides) in Water During Chloramination - Chao Zhou; Jinchao Bai; Changxuan He; Hao Wang; Jianhai Sun; Yiqiong Yang; Naiyun Gao; Xiaodong Zhang (Water, Air, & Soil Pollution, 2020)

Minor topography governing erosional distribution of SOC and temperature sensitivity of CO2 emissions: comparisons between concave and convex toposequence - Yao He; Yaxian Hu; Xin Gao; Rui Wang; Shengli Guo; Xianwen Li (Journal of Soils and Sediments, 2020)

Reduced mineral fertilization coupled with straw return in field mesocosm vegetable cultivation helps to coordinate greenhouse gas emissions and vegetable production - Rong Huang; Jiang Liu; Xinhua He; Deti Xie; Jiupai Ni; Chang Xu; Yarong Zhang; En Ci; Zifang Wang; Ming Gao (Journal of Soils and Sediments, 2020)

Endometrial autophagy is essential for embryo implantation during early pregnancy - Yan Su; Juan-Juan Zhang; Jun-Lin He; Xue-Qing Liu; Xue-Mei Chen; Yu-Bin Ding; Chao Tong; Chuan Peng; Yan-Qing Geng; Ying-Xiong Wang; Ru-Fei Gao (Journal of Molecular Medicine, 2020)

Magnetic-activated carbon composites derived from iron sludge and biological sludge for sulfonamide antibiotic removal - Junli Wan; Jian Ding; Wanchun Tan; Yinghong Gao; Shiquan Sun; Chunbo He (Environmental Science and Pollution Research, 2020)

Impact of the Three Gorges Dam on the Quality of Riverine Dissolved Organic Matter - Fanchao Xu; Liming Chen; Yifan Xu; Han Gao; He Cui; Peiyun Wei; Xiaolei Qu (Bulletin of Environmental Contamination and Toxicology, 2020)

Combined GWAS and QTL analysis for dissecting the genetic architecture of kernel test weight in maize - Xiaoxiang Zhang; Zhongrong Guan; Lei Wang; Jun Fu; Yinchao Zhang; Zhaoling Li; Langlang Ma; Peng Liu; Yanling Zhang; Min Liu; Peng Li; Chaoying Zou; et al. (Molecular Genetics and Genomics, 2020)

An Approach to Improve Soil Quality: a Case Study of Straw Incorporation with a Decomposer Under Full Film-Mulched Ridge-Furrow Tillage on the Semiarid Loess Plateau, China - Feng ke Yang; Baolin He; Ligong Zhang; Guoping Zhang; Yingping Gao (Journal of Soil Science and Plant Nutrition, 2020)

Diapause incidence and critical day length of Asian corn borer (Ostrinia furnacalis) populations exhibit a latitudinal cline in both pure and hybrid strains - Lili Huang; Jianjun Tang; Chao Chen; Haimin He; Yulin Gao; Fangsen Xue (Journal of Pest Science, 2020)

Belowground responses of woody plants to nitrogen addition in a phosphorus-rich region of northeast China - Jing Guo; Yingzhi Gao; David M. Eissenstat; Chunguang He; Lianxi Sheng (Trees, 2020)

Establishment of an Open, Sugar-Free Tissue Culture System for Sugarcane Micropropagation - Jia-ju Lu; Ahmad Ali; Er-qi He; Guo-qiong Yan; Tira-umphon Arak; San-Ji Gao (Sugar Tech, 2020)

Polyploidization of Plumbago auriculata Lam. in vitro and its characterization including cold tolerance - Yulan Jiang; Shiliang Liu; Ju Hu; Guangti He; Yingqi Liu; Xi Chen; Ting Lei; Qiao Li; Lijuan Yang; Wenji Li; Di Hu; Jiani Li; et al. (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

miR-142a-3p promotes the proliferation of porcine hemagglutinating encephalomyelitis virus by targeting Rab3a - Peng Fan; Jiyu Guan; Wenqi He; Xiaoling Lv; Shiyu Hu; Yungang Lan; Kui Zhao; Feng Gao; Fang Li; Gencheng Fan; Hongbin He; Zi Li (Archives of Virology, 2020)

Plant extracellular vesicles - Yong Cui; Jiayang Gao; Yilin He; Liwen Jiang (Protoplasma, 2020)

Changes in biochar properties in typical loess soil under a 5-year field experiment - Lianshuai Tan; Cengceng Sun; Ying Wang; Tongtong Wang; Gao-Lin Wu; Honghua He; Jiyong Zheng (Journal of Soils and Sediments, 2020)

Acute changes in colonic PGE2 levels as a biomarker of efficacy after treatment of the Pirc (F344/NTac-Apc am1137) rat with celecoxib - Changhong Yun; Wan-Mohaiza Dashwood; Li Li; Taijun Yin; Ahmet M. Ulusan; Katherine Shatzer; Song Gao; Ke-He Ruan; Ming Hu (Inflammation Research, 2020)

A Bayesian approach to seismic inversion based on GASA algorithm - Rui-qing Hu; Yan-chun Wang; Yang Gao; Shao-he Cao; Zhan-wei Yue; Qi Wang (Arabian Journal of Geosciences, 2020)

Imaging and Spectral Characteristics of Amyloid Plaque Autofluorescence in Brain Slices from the APP/PS1 Mouse Model of Alzheimer’s Disease - Yunling Gao; Qing Liu; Lingling Xu; Ning Zheng; Xiaoming He; Fuqiang Xu (Neuroscience Bulletin, 2019)

The effects of irrigation and fertilization on the migration and transformation processes of main chemical components in the soil profile - Anyan Hu; Zhaoyu Yu; Xiuhua Liu; Wande Gao; Yi He; Junyuan Li (Environmental Geochemistry and Health, 2019)

Isolation and characterization of hydrophilic dissolved organic matter in waters by ion exchange solid phase extraction followed by high resolution mass spectrometry - Wei Wang; Chen He; Yuan Gao; Yahe Zhang; Quan Shi (Environmental Chemistry Letters, 2019)

Prediction of exploration targets based on integrated analyses of source rock and simulated hydrocarbon migration direction: a case study from the gentle slope of Shulu Sag, Bohai Bay Basin, northern China - Changqing Ren; Fugui He; Xianzhi Gao; Dongsheng Wu; Wenli Yao; Jianzhang Tian; Huiping Guo; Yuanxin Huang; Li Wang; Han Feng; Junwei Li (Geosciences Journal, 2019)

Carbamazepine promotes specific stimuli-induced NLRP3 inflammasome activation and causes idiosyncratic liver injury in mice - Zhilei Wang; Guang Xu; Xiaoyan Zhan; Youping Liu; Yuan Gao; Nian Chen; Yuming Guo; Ruisheng Li; Tingting He; Xueai Song; Ming Niu; Jiabo Wang; et al. (Archives of Toxicology, 2019)

Elevated insulin levels compromise endometrial decidualization in mice with decrease in uterine apoptosis in early-stage pregnancy - Chen Zhang; Chengshun Yang; Na Li; Xueqing Liu; Junlin He; Xuemei Chen; Yubin Ding; Chao Tong; Chuan Peng; Hubin Yin; Yingxiong Wang; Rufei Gao (Archives of Toxicology, 2019)

The Upper Permian volcanic-sedimentary succession in northern Qamdo Block, central Qinghai-Tibet Plateau and its sedimentary, paleogeographic and tectonic significance - Shengqian Liu; Zaixing Jiang; Yi Gao; Youbin He; Chao Han (Arabian Journal of Geosciences, 2019)

3D inversion modeling of joint gravity and magnetic data based on a sinusoidal correlation constraint - Xiu-He Gao; Sheng-Qing Xiong; Zhao-Fa Zeng; Chang-Chun Yu; Gui-Bin Zhang; Si-Yuan Sun (Applied Geophysics, 2019)

Profiling of lysine-acetylated proteins in human urine - Weiwei Qin; Ting Wang; He Huang; Youhe Gao (Science China Life Sciences, 2019)