Kinetics and Size Effects on Adsorption of Cu(II), Cr(III), and Pb(II) Onto Polyethylene, Polypropylene, and Polyethylene Terephthalate Microplastic Particles - Xiaoxin Han; Shiyu Wang; Xue Yu; Rolf D. Vogt; Jianfeng Feng; Lifang Zhai; Weiqi Ma; Lin Zhu; Xueqiang Lu (Frontiers in Marine Science, 2021)
Due to its small size, large specific surface area and hydrophobicity, microplastics, and the adsorbed contaminants may together cause potential negative effects on ecosystems and human beings. In this study, kinetics and size effects on adsorption of Cu(II), Cr(III), and Pb(II) onto PE, PP and PET microplastic particles were explored. Results indicated that the PE and PET microplastics have the higher adsorption capacity for Cu(II), Cr(III), and Pb(II) than that for PP microplastic. The adsorption capacity was affected by microplastic types and metal species. Among the three metals, Pb(II) had the largest adsorption amount on microplastic particles, especially on PET particles. Moreover, the adsorption capacities of microplastics increase with the decrease of particle size. The metal adsorption capacity of <0.9 mm microplastics is greater than that of 0.9–2 mm and 2–5 mm microplastics. The size effect on metal adsorption was largest for PE microplastic. More attention should be paid in case of the coexistence of heavy metals and tiny PE and PET microplastics in the environment.

Molecular Characterization of Prdx Family and Response of Antioxidant Enzymes in Berberine Hydrochloride-Treated Charybdis japonica Infected With Aeromonas hydrophila - Mingming Han; Tianheng Gao; Yuxin Liu; Zakaria Zuraini; Chenxi Zhu; Tongqing Zhang; Feng Ji; Qichen Jiang; Xian Sun (Frontiers in Marine Science, 2021)
Berberine hydrochloride is an isoquinoline alkaloid, which has antitumoral, antibacterial, and antiviral activities in vivo and in vitro . Charybdis japonica is one of the main economic species of crab in Southeast Asia. We studied the molecular mechanism of oxidative stress in berberine hydrochloride-treated C. japonica infected with Aeromonas hydrophila . C. japonica were infected with A. hydrophila after being submerged in different concentrations (0, 100, 200, and 300 mg/L) of berberine hydrochloride for 48 h. The full-length cDNA of Prx6 and the ORFs of Prx5 and PXL2A were cloned. Prx6 and PXL2A each have one conserved domain, Cys44 , and Cys81 . The Prx5 conserved domain contains three important Cys loci, Cys75 , Cys100 , and Cys76 . Prx6 was different from Prx5 and PXL2A in the Peroxiredoxin family. The transcription levels of PXL2A infected with A. hydrophila were all higher than the control. The transcription levels of C. japonica were further increased by adding berberine hydrochloride and were increased the highest at a concentration of 300 mg/L. The activities of glutathione peroxidase, superoxide dismutase, and catalase in the hepatopancreas of berberine hydrochloride-treated C. japonica infected with A. hydrophila were significantly increased compared with those only infected with A. hydrophila and the control group. The glutathione transferase activity in the hepatopancreas was significantly increased in berberine hydrochloride-treated C. japonica . The results of this study provide a new understanding of the potential role of berberine hydrochloride on the oxidative stress mechanisms of C. japonica .

Lathyrane diterpenoids from Jatropha podagrica and their antitumor activities in human osteosarcoma cells - Han-Tao Yuan; Qun-Feng Li; Tian Tian; Chun-Yan Zhang; Zou-Qin Huang; Chun-Xiang Fan; Ke Mei; Jie Zhou; Xiao-Xiang Zhai; Si-Bo Li; Jian-Yong Zhu (Natural Product Research, 2021)

The decreased expression of GW2 homologous genes contributed to the increased grain width and thousand‑grain weight in wheat-Dasypyrum villosum 6VS·6DL translocation lines - Zhiyu Feng; Long Song; Wanjun Song; Zhongqi Qi; Jun Yuan; Run Li; Haiming Han; Huifang Wang; Zhaoyan Chen; Weilong Guo; Mingming Xin; Jie Liu; et al. (Theoretical and Applied Genetics, 2021)

Evaluation of the Crack Propagation Capacity of Hard Rock Based on Stress-Induced Deformation Anisotropy and the Propagation Angle of Volumetric Strain - Qiang Han; Xia-Ting Feng; Chengxiang Yang; Rui Kong; Jun Zhao; Yan Zhang (Rock Mechanics and Rock Engineering, 2021)

Photosynthetic acclimation during low-light-induced leaf senescence in post-anthesis maize plants - Han-Yu Wu; Li-An Liu; Lei Shi; Wang-Feng Zhang; Chuang-Dao Jiang (Photosynthesis Research, 2021)

Sigma-1 Receptor Activation Suppresses Microglia M1 Polarization via Regulating Endoplasmic Reticulum–Mitochondria Contact and Mitochondrial Functions in Stress-Induced Hypertension Rats - Kokwin Ooi; Li Hu; Yi Feng; Chenzhi Han; Xiaorong Ren; Xinyi Qian; Haofeng Huang; Sijia Chen; Qi Shi; Hong Lin; Jijiang Wang; Danian Zhu; et al. (Molecular Neurobiology, 2021)

miR-451-3p alleviates myocardial ischemia/reperfusion injury by inhibiting MAP1LC3B-mediated autophagy - Xiang-Wei Lv; Zi-Feng He; Pan-Pan Zhu; Qiu-Yu Qin; Yun-Xue Han; Tong-Tong Xu (Inflammation Research, 2021)

On the Second-Year Warming in Late 2019 over the Tropical Pacific and Its Attribution to an Indian Ocean Dipole Event - Licheng Feng; Fei Liu; Rong-Hua Zhang; Xue Han; Bo Yu; Chuan Gao (Advances in Atmospheric Sciences, 2021)

Seismic inversion-based prediction of the elastic parameters of rocks surrounding roadways: a case study from the Shijiazhuang mining area of North China - Suzhen Shi; Jian Feng; Zuiliang Liu; Youchao Qi; Peifei Duan; Qi Han; Jianping Zuo (Acta Geophysica, 2021)

Warming reshaped the microbial hierarchical interactions - Yuqi Zhou; Baoyu Sun; Baohua Xie; Kai Feng; Zhaojing Zhang; Zheng Zhang; Shuzhen Li; Xiongfeng Du; Qi Zhang; Songsong Gu; Wen Song; Linlin Wang; et al. (Global Change Biology, 2021)
Global warming may alter microbially mediated ecosystem functions through reshaping of microbial diversity and modified microbial interactions. Here, we examined the effects of 5‐year experimental warming on different microbial hierarchical groups in a coastal nontidal soil ecosystem, including prokaryotes (i.e., bacteria and archaea), fungi, and Cercozoa, which is a widespread phylum of protists. Warming significantly altered the diversity and structure of prokaryotic and fungal communities in soil and additionally decreased the complexity of the prokaryotic network and fragmented the cercozoan network. By using the Inter‐Domain Ecological Network approach, the cross‐trophic interactions among prokaryotes, fungi, and Cercozoa were further investigated. Under warming, cercozoan–prokaryotic and fungal–prokaryotic bipartite networks were simplified, whereas the cercozoan–fungal network became slightly more complex. Despite simplification of the fungal–prokaryotic network, the strengthened synergistic interactions between saprotrophic fungi and certain prokaryotic groups, such as the Bacteroidetes, retained these phyla within the network under warming. In addition, the interactions within the fungal community were quite stable under warming conditions, which stabilized the interactions between fungi and prokaryotes or protists. Additionally, we found the microbial hierarchical interactions were affected by environmental stress (i.e., salinity and pH) and soil nutrients. Interestingly, the relevant microbial groups could respond to different soil properties under ambient conditions, whereas under warming these two groups tended to respond to similar soil properties, suggesting network hub species responded to certain environmental changes related to warming, and then transferred this response to their partners through trophic interactions. Finally, warming strengthened the network modules’ negative association with soil organic matters through some fungal hub species, which might trigger soil carbon loss in this ecosystem. Our study provides new insights into the response and feedback of microbial hierarchical interactions under warming scenario.

Controlling pathogenic risks of water treatment biotechnologies at the source by genetic editing means - Jie Wu; Dong‐Feng Liu; Hui‐Hui Li; Di Min; Jia‐Qi Liu; Peng Xu; Wen‐Wei Li; Han‐Qing Yu; Yong‐Guan Zhu (Environmental Microbiology, 2021)
Summary Antimicrobial‐resistant pathogens in the environment and wastewater treatment systems, many of which are also important pollutant degraders and are difficult to control by traditional disinfection approaches, have become an unprecedented treat to ecological security and human health. Here, we propose the adoption of genetic editing techniques as a highly targeted, efficient and simple tool to control the risks of environmental pathogens at the source. An ‘all‐in‐one’ plasmid system was constructed in Aeromonas hydrophila to accurately identify and selectively inactivate multiple key virulence factor genes and antibiotic resistance genes via base editing, enabling significantly suppressed bacterial virulence and resistance without impairing their normal phenotype and pollutant‐degradation functions. Its safe application for bioaugmented treatment of synthetic textile wastewater was also demonstrated. This genetic‐editing technique may offer a promising solution to control the health risks of environmental microorganisms via targeted gene inactivation, thereby facilitating safer application of water treatment biotechnologies.

Increased Cu(II) Adsorption Onto UV-Aged Polyethylene, Polypropylene, and Polyethylene Terephthalate Microplastic Particles in Seawater - Xiaoxin Han; Rolf D. Vogt; Jiaying Zhou; Boyang Zheng; Xue Yu; Jianfeng Feng; Xueqiang Lu (Frontiers in Marine Science, 2021)
Environmental effects of microplastic are rather due to their adsorption capacity of contaminants than themselves. Aging is a key factor influencing adsorption properties of environmental microplastics. In order to clarify this influence, polyethylene (PE), polypropylene (PP), and polyethylene terephthalate (PET) microplastics with particle sizes of <0.9 mm, 0.9–2 mm, and 2–5 mm were artificially aged in seawater for 12 months. This enabled an assessment of the change in Cu(II) adsorption capacity to the microplastics particles under aging. According to the FTIR spectra, fresh microplastics were oxidized during the UV induced aging process. The adsorption capacities of microplastic were positively correlated with their aging time. After 12-months aging, the amount of Cu(II) adsorbed to the aged microplastics was 1.45–2.92 times higher than on the fresh microplastic particles. For PP and PET, the aging effect increased with decreasing size of the microplastic particles. In the case of PE, particles with the medium particle size (0.9–2 mm) had the strongest aging effect.

Daily Streamflow Forecasting Based on Flow Pattern Recognition - Fang-Fang Li; Han Cao; Chun-Feng Hao; Jun Qiu (Water Resources Management, 2021)

Expression of the SPL-like gene LaSPL9 in Japanese larch (Larix leptolepis) is regulated by miR156 during somatic embryogenesis - Li-feng Zhang; Yan-ru Fan; Qian Lan; Li-wang Qi; Su-ying Han (Trees, 2021)

Interdecadal variations of persistent extreme heat events in eastern China under global warming - Naihui Zang; Junhu Zhao; Pengcheng Yan; Han Zhang; Shankai Tang; Guolin Feng (Theoretical and Applied Climatology, 2021)

Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult Mice - Lin Chen; Shu-Yu Ren; Rui-Xue Li; Kun Liu; Jing-Fei Chen; Yu-Jian Yang; Yong-Bin Deng; Han-Zhi Wang; Lan Xiao; Feng Mei; Fei Wang (Neuroscience Bulletin, 2021)
Exposure to chronic hypoxia is considered to be a risk factor for deficits in brain function in adults, but the underlying mechanisms remain largely unknown. Since active myelinogenesis persists in the adult central nervous system, here we aimed to investigate the impact of chronic hypoxia on myelination and the related functional consequences in adult mice. Using a transgenic approach to label newly-generated myelin sheaths ( NG2-CreER TM ; Tau-mGFP ), we found that myelinogenesis was highly active in most brain regions, such as the motor cortex and corpus callosum. After exposure to hypoxia (10% oxygen) 12 h per day for 4 weeks, myelinogenesis was largely inhibited in the 4-month old brain and the mice displayed motor coordination deficits revealed by the beam-walking test. To determine the relationship between the inhibited myelination and functional impairment, we induced oligodendroglia-specific deletion of the transcription factor Olig2 by tamoxifen ( NG2-CreER TM ; Tau-mGFP; Olig2 fl/fl ) in adult mice to mimic the decreased myelinogenesis caused by hypoxia. The deletion of Olig2 inhibited myelinogenesis and consequently impaired motor coordination, suggesting that myelinogenesis is required for motor function in adult mice. To understand whether enhancing myelination could protect brain functions against hypoxia, we treated hypoxic mice with the myelination-enhancing drug-clemastine, which resulted in enhanced myelogenesis and improved motor coordination. Taken together, our data indicate that chronic hypoxia inhibits myelinogenesis and causes functional deficits in the brain and that enhancing myelinogenesis protects brain functions against hypoxia-related deficits.

Defective Autophagy and Mitophagy in Alzheimer’s Disease: Mechanisms and Translational Implications - Jie Chen; Hai-Jun He; Qianqian Ye; Feifei Feng; Wen-Wen Wang; Yingying Gu; Ruiyu Han; Chenglong Xie (Molecular Neurobiology, 2021)

Evaluating the efficacy of osthole and matrine for control of Sorghum purple spot - Yubo Sun; Yue Chen; Ting Liu; Yingying Wang; Yong Wang; Lirong Han; Zhiqing Ma; Juntao Feng (Journal of Plant Diseases and Protection, 2021)

Long-term high-intensity interval training increases serum neurotrophic factors in elderly overweight and obese Chinese adults - Xi Li; Tianyu Han; Xu Zou; Han Zhang; Wenpin Feng; Han Wang; Yulin Shen; Li Zhang; Guoliang Fang (European Journal of Applied Physiology, 2021)

Distribution of ammonia-oxidizing archaea and bacteria along an engineered coastal ecosystem in subtropical China - Yong-Feng Wang; Ji-Dong Gu; Richard P. Dick; Wei Han; Hui-Xiao Yang; Huan-Qin Liao; Yi Zhou; Han Meng (Ecotoxicology, 2021)

Low-Se Diet Can Affect Sperm Quality and Testicular Glutathione Peroxidase-4 activity in Rats - Qin Wang; Shuo Zhan; Yiqun Liu; Feng Han; Lili Shi; Chao Han; Weipeng Mu; Jizhong Cheng; Zhen-wu Huang (Biological Trace Element Research, 2021)

Expression analysis and tissue localization of IgZ in the grouper Epinephelus coioides after Vibrio alginolyticus infection and vaccination - Yao‐Wu Fu; Zhan‐Juan Yao; Meng‐Han He; Zuo‐Pei Wang; Wei‐Feng Chen; Miao Cui; Qi‐Zhong Zhang (Journal of Fish Diseases, 2021)
The orange‐spotted grouper ( Epinephelus coioides ) is an important marine farmed fish in China. It is affected by the bacterial pathogen Vibrio alginolyticus , which causes high mortality and substantial economic losses. We studied the transcriptional changes of the IgZ gene in E. coioides following V. alginolyticus stimulation and investigated the distribution of IgZ in different tissues. The highest expression level of IgZ occurred in the head kidney. When fish were stimulated with live and inactivated V. alginolyticus , the expression levels of IgZ in the head kidney, spleen, intestine, gills and blood cells were significantly upregulated. In an in situ hybridization study, IgZ mRNA‐positive cells were detected in the head kidney, spleen and gill, but positive signals were not detected in the liver and intestine. IgZ‐labelled cells increased in the head kidney, spleen and gills post‐infection with V. alginolyticus for 21 days. The present study provides additional evidence that IgZ is involved in mucosal immune responses and helps explain the role of IgZ in E . coioides defence against V . alginolyticus infection.

Network pharmacology predicted HDAC6 as a potential target of flavones from Daphne giraldii on hepatocellular carcinoma - Jing-Jie Chen; Xin-Yue Shang; Feng-Ying Han; Yue Zhang; Dian Zhao; Guo-Dong Yao; Shao-Jiang Song (Natural Product Research, 2021)

Sesquiterpenoids from Artemisia argyi and their NO production inhibitory activity in RAW264.7 cells - Gui-Min Xue; Jin-Feng Xue; Chen-Guang Zhao; Zhen-Zhu Zhao; Yan-Jun Sun; Kun Du; Han-Wei Li; Wei-Sheng Feng (Natural Product Research, 2021)

Distinctive role of fluG in the adaptation of Beauveria bassiana to insect‐pathogenic lifecycle and environmental stresses - Chong‐Tao Guo; Han Peng; Sen‐Miao Tong; Sheng‐Hua Ying; Ming‐Guang Feng (Environmental Microbiology, 2021)
Summary The upstream developmental activation (UDA) pathway comprises three fluG ‐cored cascades ( fluG‐flbA , fluG‐flbE/B/D and fluG‐flbC ) that activate the key gene brlA of central developmental pathway (CDP) to initiate conidiation in aspergilli. However, the core role of fluG remains poorly understood in other fungi. Here, we report distinctive role of fluG in the insect‐pathogenic lifecycle of Beauveria bassiana . Disruption of fluG resulted in limited conidiation defect, which was mitigated with incubation time and associated with time‐course up‐regulation/down‐regulation of all flb and CDP genes and another fluG ‐like gene (BBA_06309). In Δ fluG , increased sensitivities to various stresses correlated with repression of corresponding stress‐responsive genes. Its virulence through normal cuticle infection was attenuated greatly due to blocked secretion of cuticle‐degrading enzymes and delayed formation of hyphal bodies (blastospores) to accelerate proliferation in vivo and host death. In submerged Δ fluG cultures mimicking insect haemolymph, largely increased blastospore production concurred with drastic up‐regulation of the CDP genes brlA and abaA , which was associated with earlier up‐regulation of most flb genes in the cultures. Our results unveil an essentiality of fluG for fungal adaptation to insect‐pathogenic lifecycle and suggest the other fluG ‐like gene to act as an alternative player in the UDA pathway of B . bassiana .

Two white collar proteins protect fungal cells from solar UV damage by their interactions with two photolyases in Metarhizium robertsii - Han Peng; Chong‐Tao Guo; Sen‐Miao Tong; Sheng‐Hua Ying; Ming‐Guang Feng (Environmental Microbiology, 2021)
Summary The photolyases PHR1 and PHR2 enable photorepair of fungal DNA lesions in the forms of UV‐induced cyclobutane pyrimidine dimer (CPD) and (6‐4)‐pyrimidine‐pyrimidone (6‐4PP) photoproducts, but their regulation remains mechanistically elusive. Here, we report that the white collar proteins WC1 and WC2 mutually interacting to form a light‐responsive transcription factor regulate photolyase expression required for fungal UV resistance in the insect‐pathogenic fungus Metharhizum robertsii . Conidial UVB resistance decreased by 54% in Δ wc1 and 67% in Δ wc2 . Five‐hour exposure of UVB‐inactivated conidia to visible light resulted in photoreactivation rates of 30% and 9% for the Δ wc1 and Δ wc2 mutants, contrasting to 79%–82% for wild‐type and complemented strains. Importantly, abolished transcription of phr1 in Δ wc‐2 and of phr2 in Δ wc1 resulted in incapable photorepair of CDP and 6‐4PP DNA lesions in UVB‐impaired Δ wc2 and Δ wc1 cells respectively. Yeast two‐hybrid assays revealed interactions of either WC protein with both PHR1 and PHR2. Therefore, the essential roles for WC1 and WC2 in both photorepair of UVB‐induced DNA lesions and photoreactivation of UVB‐inactivated conidia rely upon their interactions with, and hence transcriptional activation of, PHR1 and PHR2. These findings uncover a novel WC‐cored pathway that mediates filamentous fungal response and adaptation to solar UV irradiation.

Omega-3 fatty acid protects cardiomyocytes against hypoxia-induced injury through targeting MiR-210-3p/CASP8AP2 axis - Xueju Yu; Fengyao Liu; Yuting Liu; Bingqing Bai; Han Yin; Haochen Wang; Yingqing Feng; Huan Ma; Qingshan Geng (Molecular and Cellular Biochemistry, 2021)

Involvement of Putrescine, Nitric Oxide, and Hydrogen Peroxide in Methyl Jasmonate-Induced Ginsenoside Synthesis in Adventitious Root Cultures of Panax ginseng C.A. Meyer - Xiao-Han Wu; Ming-Zhi Fan; Xue-Feng Li; Xuan-Chun Piao; Ri Gao; Mei-Lan Lian (Journal of Plant Growth Regulation, 2021)

Screening and application of SSR markers related to seed storability traits in maize (Zea mays L.) - Xiaoyang Guo; Xiaohui Sun; Shan Liu; Chengxu Gong; Chenchen Feng; Xiao Han; Tingting Lv; Yu Zhou; Zhenhua Wang; Hong Di (Genetic Resources and Crop Evolution, 2021)

Complete genome sequence of the Pseudomonas oleovorans strain ODT-83 isolated from oyster - Mingshu Yang; Feng Han; Yongxin Yu; Yongjie Wang (Archives of Microbiology, 2021)

Kinetic and Thermodynamic Features of Pb(II) Removal From Aqueous Solution by Leonardite-Derived Humic Acid - Fande Meng; Yuwei Zhang; Yongbing Cai; Guodong Yuan; Feng X. Han (Water, Air, & Soil Pollution, 2021)

A new view on the trend of solar radiation in mainland China — based on the optimized empirical model - Zihao Feng; Bin Guo; Han Xu; Liguo Zhang; Jie Xu; Ying Xu (Theoretical and Applied Climatology, 2021)

Wheat-root associated prokaryotic community: interplay between plant selection and location - Yuyin Zheng; Zhihan Feng; Jialong Wang; Xiaoman Huang; Li Lei; Xue Zhang; Huili Cao; Dandan Fan; Minjie Yao; Dejun Han; Xiangzhen Li (Plant and Soil, 2021)

Green-synthesized nanosize Mont-supported Fe0 via tea extract for enhanced transport and in situ remediation of Pb(II) in soil - Han Yang; Zhi Ye; Fang Feng; Nan Xu; Jing Yang; Zihan Yao; Zuling Li; Jianping Chen (Journal of Soils and Sediments, 2021)

A luminescent Zn(II)-Containing Complex: Selective Sensing of Cr(VI) Anion and Application Values on Tuberculosis Care Through Increasing the Antibacterial Response of Macrophages - Jin-Chao Mao; Jin-Jing Hong; Ming-Zheng Lin; Feng Han; Dong Li (Journal of Fluorescence, 2021)

Establishment of an indirect ELISA-based method involving the use of a multiepitope recombinant S protein to detect antibodies against canine coronavirus - Yun-Feng Hao; Shao-Han Li; Guang-Zhi Zhang; Yi Xu; Guang-zong Long; Xiao-xiong Lu; Shang-Jin Cui; Tong Qin (Archives of Virology, 2021)

Can precrops uplift subsoil nutrients to topsoil? - Eusun Han; Feng Li; Ute Perkons; Paul Martin Küpper; Sara L. Bauke; Miriam Athmann; Kristian Thorup-Kristensen; Timo Kautz; Ulrich Köpke (Plant and Soil, 2021)

The Educational Program for Healthcare Providers Regarding Fertility Preservation for Cancer Patients: a Systematic Review - Han-feng Zhang; Qing-hua Jiang; Gui-yu Huang; Jun Kako; Kohei Kajiwara; Jian-xia Lyu; Mika Miyashita (Journal of Cancer Education, 2021)

Acute effects of ambient air pollution on clinic visits of college students for upper respiratory tract infection in Wuhan, China - Faxue Zhang; Han Zhang; Chuangxin Wu; Miaoxuan Zhang; Huan Feng; Dejia Li; Wei Zhu (Environmental Science and Pollution Research, 2021)

Paleoclimatic proxies from global closed basins and the possible beginning of Anthropocene - Yu Li; Qin Han; Lu Hao; Xinzhong Zhang; Dawei Chen; Yuxin Zhang; Lingmei Xu; Wangting Ye; Simin Peng; Yichan Li; Zhuowen Feng; Hebin Liu (Journal of Geographical Sciences, 2021)

Unraveling Street-Level Air Pollution upon a Pivotal City of Yangtze River Delta, China - Rui Feng; Han Gao; Zhuo Wang; Kun Luo; Jian-ren Fan; Hui-jun Zheng (Aerosol Science and Engineering, 2021)

Overcoming diverse homologous recombinations and single chimeric guide RNA competitive inhibition enhances Cas9‐based cyclical multiple genes coediting in filamentous fungi - Youzhi Miao; Yanwei Xia; Yanqiong Kong; Han Zhu; Huiling Mei; Pan Li; Haichao Feng; Weibing Xun; Zhihui Xu; Nan Zhang; Dongyang Liu; Qirong Shen; et al. (Environmental Microbiology, 2021)
Summary Deciphering the complex cellular behaviours and advancing the biotechnology applications of filamentous fungi increase the requirement for genetically manipulating a large number of target genes. The current strategies cannot cyclically coedit multiple genes simultaneously. In this study, we firstly revealed the existence of diverse homologous recombination (HR) types in marker‐free editing of filamentous fungi, and then, demonstrated that sgRNA efficiency‐mediated competitive inhibition resulted in the low integration of multiple genetic sites during coediting, which are the two major obstacles to limit the efficiency of cyclically coediting of multiple genes. To overcome these obstacles, we developed a biased cutting strategy by Cas9 to greatly enhance the desired HR type and applied a new selection marker labelling strategy for multiple donor DNAs, in which only the donor DNA with the lowest sgRNA efficiency was labelled. Combined with these strategies, we successfully developed a convenient method for cyclically coediting multiple genes in different filamentous fungi. In addition, diverse HRs resulted in a useful and convenient one‐step approach for gene functional study combining both gene disruption and complementation. This research provided both a useful one‐step approach for gene functional study and an efficient strategy for cyclically coediting multiple genes in filamentous fungi.

Kelp aquaculture in China: a retrospective and future prospects - Zi‐Min Hu; Ti‐Feng Shan; Jie Zhang; Quan‐Sheng Zhang; Alan T. Critchley; Han‐Gil Choi; Norishige Yotsukura; Fu‐Li Liu; De‐Lin Duan (Reviews in Aquaculture, 2021)
Globally, China has the largest scale of kelp cultivation and production operations. However, its kelp aquaculture industry is suffering from declining germplasm diversity, degradation of agronomic traits, the presence of polluted environments, changing ocean conditions and increasing anthropological interference. This review covers two of the most commercially important kelp species in China, viz. Saccharina japonica and Undaria pinnatifida . It summarizes the history of their cultivation, production, economic and ecological benefits, their breeding programmes (e.g. inter‐ and intra‐specific hybridization and marker‐assisted selection) and efforts towards population genetic diversity and conservation. The article focuses on three significant challenges, for example genetic cross‐contamination between the wild and farmed kelp populations, ocean warming and ocean acidification. Accordingly, we outline the steps required to provide several intervention measures, for example (i) collection and preservation of wild and cultivated kelp germplasm; (ii) selection of suitable cultivation sites under changing environmental conditions; (iii) developing stress‐resistant cultivars; and finally, (iv) adoption of innovative cultivation models. The review concludes with genome‐based, designs for molecular breeding and calls for the establishment of an East Asian Kelp Consortium (EAKC). Collectively, the Chinese kelp industry could provide beneficial goods and services, for example bioenergy to fine chemicals and environmental benefits, such as carbon capture, pH amelioration and provision of habitat for many other marine species of commercial value. The strategies proposed in this article thus have the potential to not only improve but also reinvigorate the kelp industry in China and nearby Japan and Korea, in the context of both environmental health and economic benefits.

Cover Image - Zi‐Min Hu; Ti‐Feng Shan; Jie Zhang; Quan‐Sheng Zhang; Alan T. Critchley; Han‐Gil Choi; Norishige Yotsukura; Fu‐Li Liu; De‐Lin Duan (Reviews in Aquaculture, 2021)
The cover image is based on the Review Article Kelp aquaculture in China: A retrospective and future prospects by Zi‐Min Hu et al., https://doi.org/10.1111/raq.12524 . image

Large Deformation Control of Deep Roadways in Fractured Hard Rock Based on Cracking-Restraint Method - Yue-Mao Zhao; Xia-Ting Feng; Quan Jiang; Yong Han; Yang-Yi Zhou; Hui-Gao Guo; Yong-Yuan Kou; Ying-En Shi (Rock Mechanics and Rock Engineering, 2021)

Affinities of freshwater “Chantransia” stage algae (Rhodophyta) from China based on molecular and morphological analyses - Jinfen Han; Fangru Nan; Jia Feng; Junping Lü; Qi Liu; Xudong Liu; Shulian Xie (Journal of Oceanology and Limnology, 2021)

Clozapine Induced Developmental and Cardiac Toxicity on Zebrafish Embryos by Elevating Oxidative Stress - Feng Zhang; Liwen Han; Jiazhen Wang; Minglei Shu; Kechun Liu; Yun Zhang; ChungDer Hsiao; Qingping Tian; Qiuxia He (Cardiovascular Toxicology, 2021)

Cladosporine A, a new indole diterpenoid alkaloid with antimicrobial activities from Cladosporium sp. - Xue Han; Xue-Feng Bao; Chuan-Xi Wang; Jun Xie; Xiao-Jun Song; Ping Dai; Guo-Dong Chen; Dan Hu; Xin-Sheng Yao; Hao Gao (Natural Product Research, 2021)

GTree: an Open-source Tool for Dense Reconstruction of Brain-wide Neuronal Population - Hang Zhou; Shiwei Li; Anan Li; Qing Huang; Feng Xiong; Ning Li; Jiacheng Han; Hongtao Kang; Yijun Chen; Yun Li; Huimin Lin; Yu-Hui Zhang; et al. (Neuroinformatics, 2021)

The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study - Wanli Kang; Jian Du; Song Yang; Jiajia Yu; Hongyan Chen; Jianxiong Liu; Jinshan Ma; Mingwu Li; Jingmin Qin; Wei Shu; Peilan Zong; Yi Zhang; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

The Fe3O4-modified biochar reduces arsenic availability in soil and arsenic accumulation in indica rice (Oryza sativa L.) - Yao Yao; Hang Zhou; Xiu-Lan Yan; Xiao Yang; Kang-Wen Huang; Juan Liu; Li-Juan Li; Jing-Yi Zhang; Jiao-Feng Gu; Yaoyu Zhou; Bo-Han Liao (Environmental Science and Pollution Research, 2021)

To the light side: molecular diversity and morphology of stomatopod larvae and juveniles (Crustacea: Malacostraca: Stomatopoda) from crustose coralline algal reefs in Taiwan - Kingsley J. H. Wong; Yao-Feng Tsao; Pei-Chen Tsai; Wei-Peng Hsieh; Han-Ru Li; Ryuji J. Machida; Benny K. K. Chan (Marine Biodiversity, 2021)

GREAT-UPD: An open-source software for uncalibrated phase delay estimation based on multi-GNSS and multi-frequency observations - Xingxing Li; Xinjuan Han; Xin Li; Gege Liu; Guolong Feng; Bo Wang; Hongjie Zheng (GPS Solutions, 2021)

New secondary metabolite with cytotoxicity from spawning soft coral Asterospicularia laurae in Taiwan - Jui-Hsin Su; Chih-I Liu; Mei-Chin Lu; Chi-I Chang; Min-Ying Hsieh; Yu-Chi Lin; Chang-Feng Dai; Ya-Han Zhang; Zheng-Yu Lin; Yun-Sheng Lin (Natural Product Research, 2021)

Principles and uncertainties of 14 C age estimations for groundwater transport and resource evaluation - Liang-Feng Han; Leonard I. Wassenaar (Isotopes in Environmental and Health Studies, 2021)

Evaluation Method of Rock Brittleness under True Triaxial Stress States Based on Pre-peak Deformation Characteristic and Post-peak Energy Evolution - Yan Zhang; Xia-Ting Feng; Chengxiang Yang; Qiang Han; Zhaofeng Wang; Rui Kong (Rock Mechanics and Rock Engineering, 2021)

The cellulose synthase (CesA) gene family in four Gossypium species: phylogenetics, sequence variation and gene expression in relation to fiber quality in Upland cotton - Sujun Zhang; Zhenxing Jiang; Jie Chen; Zongfu Han; Jina Chi; Xihua Li; Jiwen Yu; Chaozhu Xing; Mingzhou Song; Jianyong Wu; Feng Liu; Xiangyun Zhang; et al. (Molecular Genetics and Genomics, 2021)

Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis - Tsung-Ying Tsai; Li-Wei Lo; Shin-Huei Liu; Wen-Han Cheng; Yu-Hui Chou; Wei-Lun Lin; Yenn-Jiang Lin; Shih-Lin Chang; Yu-Feng Hu; Fa-Po Chung; Jo-Nan Liao; Tze-Fan Chao; et al. (Environmental Science and Pollution Research, 2021)

Dietary Serine and Sulfate-Containing Amino Acids Related to the Nutritional Status of Selenium in Lactating Chinese Women - Feng Han; Xuehong Pang; Qin Wang; Yiqun Liu; Liping Liu; Yingjuan Chai; Jie Zhang; Shijin Wang; Jiaxi Lu; Licui Sun; Shuo Zhan; Hongying Wu; et al. (Biological Trace Element Research, 2021)

Serum Ceruloplasmin Is the Candidate Predictive Biomarker for Acute Aortic Dissection and Is Related to Thrombosed False Lumen: a Propensity Score–Matched Observational Case–Control Study - Changcheng Ma; Haibin Zhao; Feng Shi; Mu Li; Xun Liu; Chao Ji; Yanshuo Han (Biological Trace Element Research, 2021)

Transcriptional and post-transcriptional regulation of the miR171-LaSCL6 module during somatic embryogenesis in Larix kaempferi - Qiao-Lu Zang; Yao Zhang; Su-Ying Han; Wan-Feng Li; Li-Wang Qi (Trees, 2021)
Key message Expression analysis of Larix kaempferi mature miR171s and their primary transcripts and target gene LaSCL6 during somatic embryogenesis revealed the transcriptional and post-transcriptional regulation of the miR171- LaSCL6 module. Abstract Somatic embryogenesis provides a useful experimental system for studying the regulatory mechanisms of plant development. The level and activity of microRNA171 (miR171) fluctuate during somatic embryogenesis in Larix kaempferi , but the underlying mechanisms are still unclear. Here, in L. kaempferi we identified five members of the miR171 family, which cleave LaSCL6 mRNA at different sites. In addition, we improved the method of measuring miRNA activity in a more direct way. Furthermore, we measured the expression patterns of mature miR171s and their primary transcripts during somatic embryogenesis in L. kaempferi and found that their patterns differed, indicating that the transcription of MIR171 genes and the subsequent cleavage of their intermediate products are regulated. Taken together, our findings not only offer a means to study the regulation of miRNA activity, but also provide further insight into the regulation of L . kaempferi somatic embryogenesis by miR171- LaSCL6 .

Curcumin protects thymus against D-galactose-induced senescence in mice - Jie-han Li; Ting-ting Wei; Li Guo; Jia-hui Cao; Yuan-kang Feng; Shu-ning Guo; Guo-hong Liu; Yi Ding; Yu-rong Chai (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Spatial variation in macrobenthic assemblages and their relationship with environmental factors in the upstream and midstream regions of the Heihe River Basin, China - Yu Wang; Juan-Juan Liu; Wei Liu; Qi Feng; Bao-long Li; Han Lu; Shuang Wang (Environmental Monitoring and Assessment, 2021)
The Heihe River is a typical inland river under increasing anthropogenic pressure. To explore the characteristics of the macrobenthic assemblages and their relationships with environmental factors in the upstream and midstream regions of this basin, abiotic conditions and macrobenthic assemblages were investigated in the summers of 2018 and 2019. A total of 50 species were collected, and Arthropoda and mollusks were the dominant groups. A significant increase in standing stock was observed from the upstream to midstream, and predators (PR) were the main functional feeding group. A one-way analysis of variance (ANOVA) revealed that the Shannon-Wiener index and Margalef’s index values significantly differed at the spatial scale ( P < 0.05). A redundancy analysis (RDA) and Pearson correlation analysis showed that the spatial heterogeneity of the macrobenthos was influenced by the biochemical oxygen demand (BOD 5 ), water temperature (WT), total nitrogen (TN), salinity, electrical conductivity (EC), total dissolved solids (TDS), dissolved oxygen (DO), and potassium permanganate index (COD Mn ) ( P < 0.05). The spatial variation of macrobenthos was mainly governed by natural conditions and human disturbances.

Cerebral microbleeds and their influence on cognitive impairment in Dialysis patients - Yujun Qian; Ke Zheng; Haiyun Wang; Hui You; Fei Han; Jun Ni; Bo Hou; Limeng Chen; Yicheng Zhu; Feng Feng; Xuemei Li (Brain Imaging and Behavior, 2021)

Rapid and highly efficient genomic engineering with a novel iEditing device for programming versatile extracellular electron transfer of electroactive bacteria - Yang‐Yang Fan; Qiang Tang; Yang Li; Feng‐He Li; Jing‐Hang Wu; Wen‐Wei Li; Han‐Qing Yu (Environmental Microbiology, 2021)
Summary The advances in synthetic biology bring exciting new opportunities to reprogram microorganisms with novel functionalities for environmental applications. For real‐world applications, a genetic tool that enables genetic engineering in a stably genomic inherited manner is greatly desired. In this work, we design a novel genetic device for rapid and efficient genome engineering based on the i ntron‐encoded homing‐endonuclease empowered genome editing (iEditing). The iEditing device enables rapid and efficient genome engineering in Shewanella oneidensis MR‐1, the representative strain of the electroactive bacteria group. Moreover, combining with the Red or RecET recombination system, the genome‐editing efficiency was greatly improved, up to approximately 100%. Significantly, the iEditing device itself is eliminated simultaneously when genome editing occurs, thereby requiring no follow‐up to remove the encoding system. Then, we develop a new extracellular electron transfer (EET) engineering strategy by programming the parallel EET systems to enhance versatile EET. The engineered strains exhibit sufficiently enhanced electron output and pollutant reduction ability. Furthermore, this device has demonstrated its great potential to be extended for genome editing in other important microbes. This work provides a useful and efficient tool for the rapid generation of synthetic microorganisms for various environmental applications.

Comparative analysis of transcriptomic profiling to identify genes involved in the bulged surface of pear fruit (Pyrus bretschneideri Rehd. cv. Yuluxiangli) - Baopeng Ding; Tingting Liu; Chaohui Hu; Yuqin Song; Ruijie Hao; Xinxin Feng; Tingting Cui; Youzhi Han; Liulin Li (Physiology and Molecular Biology of Plants, 2021)

Temperature gradient method for deriving planetary boundary layer height from AIRS profile data over the Heihe River Basin of China - Xueliang Feng; Le Tang; Gang Han; Wenshuang Chen (Arabian Journal of Geosciences, 2021)

A new cyclic peptide from the fibrous root of Pseudostellaria heterophylla - Xiao-fei Zhao; Qian Zhang; Han-tao Zhao; Yan-da Zhang; Han-ru Liu; Lu-jiang Yuan; Qian-feng Chen (Natural Product Research, 2020)

Experimental Investigation of Creep Behavior of Bayer Red Mud in Guizhou Aluminum Factory's Red Mud Disposal Field - Baoyun Zhao; Wei Huang; Mengmeng Han; Yanbo Feng (Geotechnical and Geological Engineering, 2020)

Isolation and Characterization of a New Fusaricidin-Type Antibiotic Produced by Paenibacillus bovis sp. nov BD3526 - Bangqing Hua; Huafeng Feng; Jin Han; Zhenyi Qiao; Xiaohua Wang; Qiuxiang Zhang; Zhenmin Liu; Zhengjun Wu (Current Microbiology, 2020)

Pseudorabies virus production using a serum-free medium in fixed-bed bioreactors with low cell inoculum density - Jianqi Nie; Yang Sun; Feng Peng; Fei Han; Yankun Yang; Xiuxia Liu; Chunli Liu; Ye Li; Zhonghu Bai (Biotechnology Letters, 2020)

Intelligent identification method for near-surface ground fissures based on seismic data - Su-Zhen Shi; Jian-Ying Gu; Jian Feng; Pei-fei Duan; You-chao Qi; Qi Han (Applied Geophysics, 2020)

Prevalence, Molecular Characterization and Risk Factors of Blastocystis sp. from Farmed Pigs in Yunnan Province, Southwestern China - Jian Qiang Han; Zhao Li; Yang Zou; Li Hua Pu; Xin Quan Zhu; Feng Cai Zou; Cui-Qin Huang (Acta Parasitologica, 2020)

Study of the geostatistical grid maths operation method of quantifying water movement in soil layers of a cotton field * - Liyuan Liu; Fangfang Xing; Yabing Li; Yingchun Han; Zhanbiao Wang; Xiaoyu Zhi; Guoping Wang; Lu Feng; Beifang Yang; Yaping Lei; Zhengyi Fan; Wenli Du (Irrigation and Drainage, 2020)
The precise quantification of water movement in different field soil layers is important for variable‐rate irrigation and fertilization. To this end, a field experiment based on a geostatistical approach was conducted in southern Anyang, Henan, China, to examine soil water movement in a cotton field with drip irrigation by measuring the soil water content (SWC) data on a regular 100 × 80 cm grid. The result shows that the temporal and spatial variation of soil moisture decreased with the increase of soil depth at different points, and apparent spatial heterogeneity was observed under different soil conditions through a semivariogram analysis. The variation of soil moisture at different soil profiles was affected by the cotton plants and drip lines in non‐irrigation and irrigation periods respectively. The level of the change at 20 cm was more than 70 cm in the horizontal direction in the two periods, however the degree of change at 40 cm in the irrigation period was more than 70 cm in the vertical direction, while contrary results were shown in the non‐irrigation period. Moreover, the results indicated that the trapezoidal rule could be applied to quantify the volume of water movement precisely.

Responses of arbuscular mycorrhizal fungi to nitrogen addition: A meta‐analysis - Yunfeng Han; Jiguang Feng; Mengguang Han; Biao Zhu (Global Change Biology, 2020)
Arbuscular mycorrhizal (AM) fungi play important roles in carbon (C), nitrogen (N) and phosphorus (P) cycling of terrestrial ecosystems. The impact of increasing N deposition on AM fungi will inevitably affect ecosystem processes. However, generalizable patterns of how N deposition affects AM fungi remains poorly understood. Here we conducted a global‐scale meta‐analysis from 94 publications and 101 sites to investigate the responses of AM fungi to N addition, including abundance in both intra‐radical (host roots) and extra‐radical portion (soil), richness and diversity. We also explored the mechanisms of N addition affecting AM fungi by the trait‐based guilds method. Results showed that N addition significantly decreased AM fungal overall abundance (−8.0%). However, the response of abundance in intra‐radical portion was not consistent with that in extra‐radical portion: root colonization decreased (−11.6%) significantly, whereas extra‐radical hyphae length density did not change significantly. Different AM fungal guilds showed different responses to N addition: both the abundance (spore density) and relative abundance of the rhizophilic guild decreased significantly under N addition (−29.8% and −12.0%, respectively), while the abundance and relative abundance of the edaphophilic guild had insignificant response to N addition. Such inconsistent responses of rhizophilic and edaphophilic guilds were mainly moderated by the change of soil pH and the response of root biomass, respectively. Moreover, N addition had an insignificant negative effect on AM fungal richness and diversity, which was strongly related with the relative availability of soil P (i.e. soil available N/P ratio). Collectively, this meta‐analysis highlights that considering trait‐based AM fungal guilds, soil P availability and host plant C allocation can greatly improve our understanding of the nuanced dynamics of AM fungal communities under increasing N deposition.

New Model–Based Bioequivalence Statistical Approaches for Pharmacokinetic Studies with Sparse Sampling - Florence Loingeville; Julie Bertrand; Thu Thuy Nguyen; Satish Sharan; Kairui Feng; Wanjie Sun; Jing Han; Stella Grosser; Liang Zhao; Lanyan Fang; Kathrin Möllenhoff; Holger Dette; et al. (The AAPS Journal, 2020)

Phosphodiesterase 2 inhibitor Hcyb1 reverses corticosterone-induced neurotoxicity and depression-like behavior - Meng-Jia Zhu; Jing Shi; Yong Chen; Guobing Huang; Xiong-Wei Zhu; Sam Zhang; Xian-Feng Huang; Guo-Qiang Song; Han-Ting Zhang; Heng-Ming Ke; James M. O’Donnell; Li-Qun Wang; et al. (Psychopharmacology, 2020)

Impact of Chronic Stress on Attention Control: Evidence from Behavioral and Event-Related Potential Analyses - Qingjin Liu; Yong Liu; Xuechen Leng; Jinfeng Han; Feng Xia; Hong Chen (Neuroscience Bulletin, 2020)

The effect of blastomere loss during frozen embryo transfer on the transcriptome of offspring’s umbilical cord blood - Yan-Ting Wu; Ze-Han Dong; Cheng Li; Dai-Zhan Zhou; Jun-Yu Zhang; Yan Wu; Jing-Jing Xu; Yu Wang; Xiao-Qun Ye; Jian-Zhong Sheng; Li Wang; He-Feng Huang (Molecular Biology Reports, 2020)

Characterization of a Protease Hyper-Productive Mutant of Bacillus pumilus by Comparative Genomic and Transcriptomic Analysis - Yong-Cheng Liu; Lin-Li Han; Tian-Yu Chen; Yan-Bing Lu; Hong Feng (Current Microbiology, 2020)

Spatial variability of soil hydraulic conductivity and runoff generation types in a small mountainous catchment - Yong Yang; Ren-sheng Chen; Yao-xuan Song; Chun-tan Han; Zhang-wen Liu; Jun-feng Liu (Journal of Mountain Science, 2020)

Application of a monitoring and evaluation method in irrigation water efficiency* - Feng Baoqing; Cui Jing; Wu Qianming; Han Zhenzhong (Irrigation and Drainage, 2020)
Water‐saving irrigation is of high priority in China for alleviation of the water resource supply–demand contradiction. Consequently, the objectives of irrigation water efficiency (IWE) are specified in policies at the macro scale such as national economic and social development programmes and national evaluation systems of water resources management. To scientifically evaluate IWE and water‐saving irrigation efficiency and to overcome the limitations of traditional IWE evaluation methods (e.g. numerous steps and not very practical), this study presents a normative and easy‐to‐use measurement and analysis method for IWE, specifically, head and end measurement. An IWE monitoring network, comprising more than 3700 irrigation districts on national and regional scales, was developed to dynamically monitor the variation in IWE of sample irrigation districts of different sizes and types from 2008 to 2018. The monitoring results provide technical support and scientific evidence for the formulation of water conservation policies and management at the macro scale of the water conservation sector. © 2020 John Wiley & Sons, Ltd.

Effects of Drying-Rewetting Frequency on Vertical and Lateral Loss of Soil Organic Carbon in a Tidal Salt Marsh - Juanyong Li; Wendi Qu; Guangxuan Han; Feng Lu; Yingfeng Zhou; Weimin Song; Baohua Xie; Franziska Eller (Wetlands, 2020)

Creation of fertility-restored materials for Ogura CMS in Brassica oleracea by introducing Rfo gene from Brassica napus via an allotriploid strategy - Hai-long Yu; Zhi-yuan Li; Wen-jing Ren; Feng-qing Han; Li-mei Yang; Mu Zhuang; Hong-hao Lv; Yu-mei Liu; Zhi-yuan Fang; Yang-yong Zhang (Theoretical and Applied Genetics, 2020)
Key message Ogura CMS fertility-restored materials, with 18 chromosomes, normal seed setting, stable fertility and closer genetic background to the parent Chinese kale, were successfully developed in B. oleracea via a triploid strategy for the first time. Abstract Ogura cytoplasmic male sterility (CMS) is the most widely used sterile type in seed production for commercial hybrids of Brassica oleracea vegetables. However, the natural Ogura CMS restorer line has not been found in B. oleracea crops. In this study, the triploid strategy was used with the aim to create euploid B. oleracea progenies with the Rfo gene. The allotriploid AAC hybrid YL2 was used as a male parent to backcross with Ogura CMS Chinese kale. After successive backcrosses, the BC 2 Rfo -positive individual 16CMSF2-11 and its BC 3 progenies, with 18 chromosomes, were developed, which were morphologically identical to the parent Chinese kale. Compared with F 1 and BC 1 plants, it showed stable fertility performance, and regular meiosis behavior and could produce seeds normally under natural pollination. The genomic composition analysis of Rfo -positive progenies by using molecular markers showed that more than 87% of the C-genome components of BC 3 Rfo -progenies recovered to the parent Chinese kale, while most or all of the A n -genome segments were lost in 16CMSF2-11 and its progenies. The results suggested that the genetic background of Rfo -positive individuals was closer to that of the parent Chinese kale along with backcrossing. Hereof, the Ogura CMS fertility-restored materials of Chinese kale were successfully created via triploid strategy for the first time, providing a bridge for utilizing the Ogura CMS B. oleracea germplasm in the future. Moreover, our study indicates that the triploid strategy is effective for transferring genes from B. napus into B. oleracea .

Transient receptor potential ankyrin 1 contributes to the ATP-elicited oxidative stress and inflammation in THP-1-derived macrophage - Chao Tian; Xiaobo Han; Lang He; Feng Tang; Rongqi Huang; Zuoxian Lin; Shuai Li; Sihao Deng; Junjie Xu; Hualin Huang; Huifang Zhao; Zhiyuan Li (Molecular and Cellular Biochemistry, 2020)

Hydrogeochemical and statistical analysis of high fluoride groundwater in northern China - Fan Feng; Yongfeng Jia; Yu Yang; Huan Huan; Xinying Lian; Xiangjian Xu; Fu Xia; Xu Han; Yonghai Jiang (Environmental Science and Pollution Research, 2020)

Molecular characterization of an emerging reassortant mammalian orthoreovirus in China - Dandan Ye; Zhaoyang Ji; Hongyan Shi; Jianfei Chen; Da Shi; Liyan Cao; Jianbo Liu; Mingwei Li; Hui Dong; Zhaoyang Jing; Xiaobo Wang; Qiuge Liu; et al. (Archives of Virology, 2020)

Improvement of precipitable water vapour and water vapour mixing ratio profile in atmospheric infrared sounder retrievals: differential linear adjustment model - Liang Chang; Yanxing Li; Zhen Han; Guiping Feng; Yangdong Li; Yang Zhang (International Journal of Remote Sensing, 2020)

Depletion of florfenicol and florfenicol amine in eggs of laying hens and growing pullets after oral administration - Xia Li; Lu Chen; Hui Yue; Hua Feng; Enmin Xu; Xiuli Wei; Xiaoli Han; Ligang Deng; Zengmei Li (Food Additives & Contaminants: Part A, 2020)

Macrophage polarization and its role in the pathogenesis of acute lung injury/acute respiratory distress syndrome - Xuxin Chen; Jian Tang; Weizheng Shuai; Jiguang Meng; Jian Feng; Zhihai Han (Inflammation Research, 2020)

Surface heterogeneity mediated transport of hydrochar nanoparticles in heterogeneous porous media - Jing Yang; Ming Chen; Han Yang; Nan Xu; Gang Feng; Zuling Li; Chunming Su; Dengjun Wang (Environmental Science and Pollution Research, 2020)

Laboratory investigation of the mode-I fracture of sandstone caused by a combination of freeze-thaw cycles and chemical solutions - Tielin Han; Xianfeng Wang; Zhihui Li; Dawang Li; Feng Xing; Ningxu Han (Bulletin of Engineering Geology and the Environment, 2020)

Extracellular ATP affects cell viability, respiratory O2 uptake, and intracellular ATP production of tobacco cell suspension culture in response to hydrogen peroxide-induced oxidative stress - Qin-zheng Hou; Yu-pei Wang; Bao-qiang Fan; Kun Sun; Jun-yu Liang; Han-qing Feng; Ling-yun Jia (Biologia, 2020)

Responses of Primary Afferent Fibers to Acupuncture-Like Peripheral Stimulation at Different Frequencies: Characterization by Single-Unit Recording in Rats - Ran Huo; Song-Ping Han; Feng-Yu Liu; Xiao-Jing Shou; Ling-Yu Liu; Tian-Jia Song; Fu-Jun Zhai; Rong Zhang; Guo-Gang Xing; Ji-Sheng Han (Neuroscience Bulletin, 2020)

Retraction Note to: Explore on the effect of ATF6 on cell growth and apoptosis in cartilage development - Xiaofeng Han; Peng Zhang; Rong Jiang; Fei Xia; Meiling Li; Feng‑Jin Guo (Histochemistry and Cell Biology, 2020)

The changes in ENSO-induced tropical Pacific precipitation variability in the past warm and cold climates from the EC-Earth simulations - Zixuan Han; Qiong Zhang; Qin Wen; Zhengyao Lu; Guolin Feng; Tao Su; Qiang Li; Qiang Zhang (Climate Dynamics, 2020)
The El Niño-Southern Oscillation (ENSO) is one of the most significant climate variability signals. Studying the changes in ENSO-induced precipitation variability (ENSO precipitation) in the past climate offers a possibility to a better understanding of how they may change under future climate conditions. This study uses simulations performed with the European community Earth-System Model (EC-Earth) to investigate the relative contributions of dynamic effect (the circulation anomalies together with the climatological specific humidity) and thermodynamic effect (the specific humidity anomalies together with the climatological circulation) on the changes in ENSO precipitation in the past warm and cold climates, represented by the Pliocene and the Last Glacial Maximum (LGM), respectively. The results show that the changes in ENSO precipitation are intensified (weakened) over the tropical western Pacific but weakened (intensified) over the tropical central Pacific in Pliocene (LGM) compared with the pre-industrial (PI) simulation. Based on the decomposed moisture budget equation, these changes in ENSO precipitation patterns are highly related to the dynamic effect. The mechanism can be understood as follows: the zonal gradient of the mean sea surface temperature (SST) over the tropical Indo-Pacific is increased (reduced) during the Pliocene (LGM), leading to the strengthening (weakening) of Pacific Walker Circulation as well as a westward (eastward) shift. In the Pliocene, the westward shift of Walker Circulation results in an increased (decreased) ENSO-induced low-level vertical velocity variability in the tropical western Pacific (central Pacific), and, in turn, favoring convergent (divergent) moisture transport through a dynamic process, and then causing intensified (weakened) ENSO precipitation there. The opposite mechanism exists in LGM. These results suggest that changes in the zonal SST gradient over tropical Indo-Pacific under different climate conditions determine the changes in ENSO precipitation through a dynamic process.

Naphthalene exerts non-target effects on the abundance of active fungi by stimulating basidiomycete abundance - Li-ying Lan; Li Zhang; Ya Shen; Jian Zhang; Wan-qin Yang; Zhen-feng Xu; Yang Liu; Shu-qin He; Wei Zhou; Han Li; Li-xia Wang; Si-ning Liu; et al. (Journal of Mountain Science, 2020)

Evaluation of the Biodiversity Conservation Function in Liaohe Delta Wetland, Northeastern China - Wenying Yu; Ruipeng Ji; Xiuzhen Han; Long Chen; Rui Feng; Jinwen Wu; Yushu Zhang (Journal of Meteorological Research, 2020)

Roles of Wind Stress and Subsurface Cold Water in the Second-Year Cooling of the 2017/18 La Niña Event - Licheng Feng; Rong-Hua Zhang; Bo Yu; Xue Han (Advances in Atmospheric Sciences, 2020)

Long interpregnancy interval and adverse perinatal outcomes: A retrospective cohort study - Jing Lin; Han Liu; Dan-Dan Wu; Hong-Tao Hu; Hui-Hui Wang; Cheng-Liang Zhou; Xin-Mei Liu; Xiao-Jun Chen; Jian-Zhong Sheng; He-Feng Huang (Science China Life Sciences, 2020)

Widespread Os-isotopically ultradepleted mantle domains in the Paleo-Asian oceanic upper mantle: evidence from the Paleozoic Tianshan ophiolites (NW China) - Xiao-Han Gong; Ji-Feng Xu; Xi-Jun Liu; Xiao-Xiao Huang; Zhi-Guo Zhang; Hai-Long Zhou; Zheng-Yu Yang; Wen-Xia Zhao (International Journal of Earth Sciences, 2020)

Enhanced rhamnolipids production in Pseudomonas aeruginosa SG by selectively blocking metabolic bypasses of glycosyl and fatty acid precursors - Liying Lei; Feng Zhao; Siqin Han; Ying Zhang (Biotechnology Letters, 2020)

Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-related mitophagy - Yi Zhu; Xi-Qiong Han; Xue-Jiao Sun; Rui Yang; Wen-Qi Ma; Nai-Feng Liu (Apoptosis, 2020)

Effect of three Napier grass varieties on phytoextraction of Cd- and Zn-contaminated cultivated soil under mowing and their safe utilization - Wen-Jun Yang; Jiao-Feng Gu; Hang Zhou; Fang Huang; Teng-Yue Yuan; Jing-Yi Zhang; Shi-Long Wang; Zhi-Guang Sun; Hong-Wei Yi; Bo-Han Liao (Environmental Science and Pollution Research, 2020)

Influence of atmospheric rivers on the Leeuwin Current system - Toshiaki Shinoda; Weiqing Han; Luis Zamudio; Xue Feng (Climate Dynamics, 2020)

Study on Pollution Characterization and Source Apportionment of Daytime and Nighttime PM2.5 Samples in an Urban Residential Community in Different Weather Conditions - Yan Zhao; Lihong Feng; Yuwen Wang; Bodong Shang; Jianping Li; Penghao Han (Bulletin of Environmental Contamination and Toxicology, 2020)

Using demographic model selection to untangle allopatric divergence and diversification mechanisms in the Rheum palmatum complex in the Eastern Asiatic Region - Li Feng; Markus Ruhsam; Yi‐Han Wang; Zhong‐Hu Li; Xu‐Mei Wang (Molecular Ecology, 2020)
Allopatric divergence is often initiated by geological uplift and restriction to sky‐islands, climate oscillations, or river capture. However, it can be difficult to establish which mechanism was the most likely to generate the current phylogeographical structure of a species. Recently, genomic data in conjunction with a model testing framework have been applied to address this issue in animals. To test whether such an approach is also likely to be successful in plants, we used population genomic data of the Rheum palmatum complex from the Eastern Asiatic Region, in conjunction with biogeographical reconstruction and demographic model selection, to identify the potential mechanism(s) which have led to the current level of divergence. Our results indicate that the R. palmatum complex originated in the central Hengduan Mts and possibly in regions further east, and then dispersed westward and eastward resulting in genetically distinct lineages. Populations are likely to have diverged in refugia during climate oscillations followed by subsequent expansion and secondary contact. However, model simulations within the western lineage of the R. palmatum complex cannot reject a restriction to sky‐islands as a possible mechanism of diversification due to the genetically ambiguous position of one population. This highlights that genetically mixed populations might introduce ambiguity regarding the best diversification model in some cases. Although it might be possible to resolve this ambiguity using other data, sometimes this could prove to be difficult in complex biogeographical areas.

Common Anions Affected Removal of Carbon Tetrachloride in Groundwater Using Granular Sponge Zerovalent Iron - Xueqiang Zhu; Baoping Han; Qiyan Feng (Water, Air, & Soil Pollution, 2020)

Targeting Two Antigens Associated with B-ALL with CD19-CD123 Compound Car T Cell Therapy - Lulu E. Yan; Hongyu Zhang; Masayuki Wada; Liu Fang; Jia Feng; Wenli Zhang; Qi Chen; Yuanzhen Cao; Kevin G. Pinz; Kevin H. Chen; Jessica C. Petrov; Xi Chen; et al. (Stem Cell Reviews and Reports, 2020)

Influence of Stress on Void Ratios of Compacted Crushed Rock Masses in Coal Mine Gobs - Shengyong Hu; Dandan Han; Guorui Feng; Ao Zhang; Guocai Hao; Lanqing Hu; Liping Zhu; Bo Li (Natural Resources Research, 2020)

Failure Characteristics of Surface Vertical Wells for Methane Extraction During Mining: A Case Study - Shengyong Hu; Guocai Hao; Guorui Feng; Ao Zhang; Dandan Han; Lanqing Hu (Natural Resources Research, 2020)

Short communication: recovery of Vibrio vulnificus from head ulceration in seahorse (Hippocampus kuda) - Fangyan Jiang; Ning Yang; Hai Huang; Huimin Feng; Yu Li; Bingbing Han (Aquaculture International, 2020)

Calculation Methods of Icebreaking Capability for a Double-Acting Polar Ship - Li Zhou; Feng Diao; Ming Song; Yue Han; Shifeng Ding (Journal of Marine Science and Engineering, 2020)
As a key parameter, icebreaking capability is often used to judge whether a polar ship could navigate in level ice at a certain speed. This paper presents two methods to calculate icebreaking capability. The first one is a static method based on the estimation of ice resistance under different ice thicknesses and ship speeds. The second is a dynamic method that involves solving the equation of motion. A series of model tests with a double-acting icebreaking tanker were also carried out in the ice basin of the Krylov State Research Center to measure ice resistances. The simulated ice resistances were compared with model tests results for both ahead and astern running operations. The calculated icebreaking capability based on static and dynamic methods was validated with the model test result. A good agreement was achieved between measurement and simulation. The discrepancy between the model test result and the result simulated by the static or dynamic method was minor.

Sources and ore-forming fluid pathways of carbonate-hosted Pb–Zn deposits in Southwest China: implications of Pb–Zn–S–Cd isotopic compositions - Chong Xu; Hong Zhong; Rui-Zhong Hu; Han-Jie Wen; Wei-Guang Zhu; Zhong-Jie Bai; Hai-Feng Fan; Fang-Fang Li; Ting Zhou (Mineralium Deposita, 2020)

The effect of enrichment media on the stimulation of native ureolytic bacteria in calcareous sand - Y.-J. Wang; X.-L. Han; N.-J. Jiang; J. Wang; J. Feng (International Journal of Environmental Science and Technology, 2020)

Chemical content and source apportionment of 36 heavy metal analysis and health risk assessment in aerosol of Beijing - Limeng Cui; Zhuona Wu; Peng Han; Yasuyuki Taira; Huan Wang; Qinghua Meng; Zechen Feng; Shuguang Zhai; Jun Yu; Weijie Zhu; Yuxia Kong; Hongfang Wang; et al. (Environmental Science and Pollution Research, 2020)

Assessing the interlinkage of green and blue water in an arid catchment in Northwest China - Ganquan Mao; Junguo Liu; Feng Han; Ying Meng; Yong Tian; Yi Zheng; Chunmiao Zheng (Environmental Geochemistry and Health, 2020)

H2S mediates apoptosis in response to inflammation through PI3K/Akt/NFκB signaling pathway - Yueying Wang; Chengyu Zhang; Chunmei Xu; Luping Feng; Anqi Li; Xiangyang Jin; Shuang Guo; Xianqin Jiao; Jingsong Liu; Yujie Guo; Heshui Zhu; Liqiang Han; et al. (Biotechnology Letters, 2020)

Microbial methane production is affected by secondary metabolites in the heartwood of living trees in upland forests - Huan-Long Li; Xi-Mei Zhang; Feng-Dan Deng; Xing-Guo Han; Chun-Wang Xiao; Shi-Jie Han; Zhi-Ping Wang (Trees, 2020)

Transient Receptor Potential Ankyrin 1 Contributes to Lysophosphatidylcholine-Induced Intracellular Calcium Regulation and THP-1-Derived Macrophage Activation - Chao Tian; Rongqi Huang; Feng Tang; Zuoxian Lin; Na Cheng; Xiaobo Han; Shuai Li; Peng Zhou; Sihao Deng; Hualin Huang; Huifang Zhao; Junjie Xu; et al. (The Journal of Membrane Biology, 2020)

MiR-125a-5p Regulates Vitamin D Receptor Expression in a Mouse Model of Experimental Autoimmune Encephalomyelitis - Han-Chun Long; Rui Wu; Chun-Feng Liu; Fei-Long Xiong; Zu Xu; Dian He; Yi-Fan Zhang; Bing Shao; Ping-An Zhang; Guang-Yin Xu; Lan Chu (Neuroscience Bulletin, 2020)

Petrogenesis, Tectonic Evolution and Geothermal Implications of Mesozoic Granites in the Huangshadong Geothermal Field, South China - Zhicai Xiao; Shuai Wang; Shihua Qi; Jian Kuang; Min Zhang; Feng Tian; Yongjie Han (Journal of Earth Science, 2020)

RETRACTED ARTICLE: Bimatoprost Imprinted Silicone Contact Lens to Treat Glaucoma - Feng Yan; Yanxia Liu; Shulan Han; Qingsong Zhao; Nannan Liu (AAPS PharmSciTech, 2020)

A Three-Dimensional Failure Criterion for Hard Rocks Under True Triaxial Compression - Xia-Ting Feng; Rui Kong; Chengxiang Yang; Xiwei Zhang; Zhaofeng Wang; Qiang Han; Gang Wang (Rock Mechanics and Rock Engineering, 2020)

Vertical variations in plant- and microbial-derived carbon components in grassland soils - Tian Ma; Guohua Dai; Shanshan Zhu; Dima Chen; Litong Chen; Xiaotao Lü; Xiaobo Wang; Juntao Zhu; Yangjian Zhang; Jin-Sheng He; Yongfei Bai; Xingguo Han; et al. (Plant and Soil, 2020)

Soil particle-size distribution and aggregate stability of new reconstructed purple soil affected by soil erosion in overland flow - Feng-Lin Zuo; Xiao-Yan Li; Xiao-Fan Yang; Yang Wang; Yu-Jun Ma; Yu-Han Huang; Chao-Fu Wei (Journal of Soils and Sediments, 2020)

Autism Symptoms Modulate Interpersonal Neural Synchronization in Children with Autism Spectrum Disorder in Cooperative Interactions - Qiandong Wang; Zhuo Han; Xiaoyi Hu; Shuyuan Feng; Hui Wang; Tao Liu; Li Yi (Brain Topography, 2020)

TRY plant trait database – enhanced coverage and open access - Jens Kattge; Gerhard Bönisch; Sandra Díaz; Sandra Lavorel; Iain Colin Prentice; Paul Leadley; Susanne Tautenhahn; Gijsbert D. A. Werner; Tuomas Aakala; Mehdi Abedi; Alicia T. R. Acosta; George C. Adamidis; et al. (Global Change Biology, 2020)
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits—almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.

New anthraquinone and eurotinone analogue from the seeds of Senna obtusifolia and their inhibitory effects on human organic anion transporters 1 and 3 - Xu Pang; Li-Ming Wang; You-Cai Zhang; Li-Ping Kang; He-Shui Yu; Guan-Wei Fan; Li-Feng Han (Natural Product Research, 2019)

A GH3-like gene, LaGH3, isolated from hybrid larch (Larix leptolepis × Larix olgensis) is regulated by auxin and abscisic acid during somatic embryogenesis - Li-feng Zhang; Qian Lan; Su-ying Han; Li-wang Qi (Trees, 2019)

Integrated 3D bioprinting-based geometry-control strategy for fabricating corneal substitutes - Bin Zhang; Qian Xue; Han-yi Hu; Meng-fei Yu; Lei Gao; Yi-chen Luo; Yang Li; Jin-tao Li; Liang Ma; Yu-feng Yao; Hua-yong Yang (Journal of Zhejiang University-SCIENCE B, 2019)

Stable chlorine isotopes in saline springs from the Nangqen basin, Qinghai–Tibet Plateau: Brine genesis and evolution - Ji-Long Han; Syed-Asim Hussain; Feng-Qing Han (Journal of Earth System Science, 2019)

Thermodynamic and dynamic effects of increased moisture sources over the Tropical Indian Ocean in recent decades - Zixuan Han; Tao Su; Qiong Zhang; Qin Wen; Guolin Feng (Climate Dynamics, 2019)

Interception of sulfate deposition from a closed canopy to a forest gap edge canopy in a subalpine dragon spruce plantation - Yu Zhang; Fu-zhong Wu; Bo Tan; Zhen-feng Xu; Han Li; Jun-cheng Liu; Hai-rong Zhao; Si-yi Tan; Cheng-ming You; Wan-qin Yang (Journal of Mountain Science, 2019)

Prediction of exploration targets based on integrated analyses of source rock and simulated hydrocarbon migration direction: a case study from the gentle slope of Shulu Sag, Bohai Bay Basin, northern China - Changqing Ren; Fugui He; Xianzhi Gao; Dongsheng Wu; Wenli Yao; Jianzhang Tian; Huiping Guo; Yuanxin Huang; Li Wang; Han Feng; Junwei Li (Geosciences Journal, 2019)

Multi‐model analysis of climate impacts on plant photosynthesis in China during 2000–2015 - Hao Yan; Shao‐Qiang Wang; Jun‐Bang Wang; Yun Cao; Ling‐Ling Xu; Men‐Xin Wu; Lu Cheng; Liu‐Xi Mao; Feng‐Hua Zhao; Xian‐Zhou Zhang; Yun‐Fen Liu; Yan‐Fen Wang; et al. (International Journal of Climatology, 2019)
Differences, arising from differences in gross primary production (GPP) model structures and driving forces, have fuelled arguments concerning interannual changes of GPP in China since 2000. To better investigate the interannual variability of GPP and its covariance with climate factors in China, this study adopted a multi‐model analysis based on three GPP models (i.e., Terrestrial Ecosystem Carbon flux model [TEC], Breathing Earth System Simulator model [BESS], and MOD17 GPP model). The results show that annual GPP in China increased by 0.021–0.057 Pg C year −1 from 2000 to 2015 attributable to atmospheric‐CO 2 fertilization effects and favourable climate change, that is, increasing precipitation ( P r ) and temperature ( T a ). However, northern China and southern China had a large difference in the amplitude of these GPP changes; annual GPP increased by 0.017–0.039 Pg C year −1 in northern China but only 0.001–0.018 Pg C year −1 in southern China. Northern China and southern China occupy contrasting climate zones and this contrast produced different interannual variability of GPP through different mechanisms. Northern China has a dry climate with GPP changes sensitive to P r . As a result, more P r along with higher T a in northern China produced the strong uptrend of GPP from 2000 to 2015. In contrast, southern China has a wet climate with its GPP sensitive to solar radiation and T a . For the interval of 2000–2015, decreasing radiation plus drought exerted a negative influence on GPP in southern China. This study highlights the diverse mechanisms in which climate change affects GPP in dry and wet climate zones. A robust multi‐model analysis is preferred to reduce uncertainties arising from a single GPP model and its driving data.

Proteomics combined with BSMV-VIGS methods identified some N deficiency-responsive protein species and ABA role in wheat seedling - Guozhang Kang; Yufang Wu; Gezi Li; Pengfei Wang; Qiaoxia Han; Yonghua Wang; Yingxin Xie; Wei Feng; Dongyun Ma; Chenyang Wang; Tiancai Guo (Plant and Soil, 2019)

Quantifying Flood Frequency Modification Caused by Multi-Reservoir Regulation - Yi-han Tang; Jie-feng Wu; Pei-yi Li; Li-juan Zhang; Xiao-hong Chen; Kai-rong Lin (Water Resources Management, 2019)

Changes of plant N:P stoichiometry across a 3000-km aridity transect in grasslands of northern China - Xiao-Guang Wang; Xiao-Tao Lü; Feike A. Dijkstra; Hai-Yang Zhang; Xiao-Bo Wang; Wuyunna; Zheng-Wen Wang; Jiao Feng; Xing-Guo Han (Plant and Soil, 2019)

Seed maturation and post-harvest ripening negatively affect arabidopsis somatic embryogenesis - Han Wu; Baojian Chen; Martijn Fiers; Justyna Wróbel-Marek; Jan Kodde; Steven P. C. Groot; Gerco Angenent; Hui Feng; Leónie Bentsink; Kim Boutilier (Plant Cell, Tissue and Organ Culture (PCTOC), 2019)

Biological properties and genomics analysis of vB_KpnS_GH-K3, a Klebsiella phage with a putative depolymerase-like protein - Ruopeng Cai; Zijing Wang; Gang Wang; Hao Zhang; Mengjun Cheng; Zhimin Guo; Yalu Ji; Hengyu Xi; Xinwu Wang; Yibing Xue; Sadeeq ur Rahman; Changjiang Sun; et al. (Virus Genes, 2019)

Experimental Study on the Hydrodynamic Performance of a Heaving Buoy Assembled on a Net Cage Platform - Hongda Shi; Xiaochen Dong; Liang Feng; Zhi Han (Journal of Ocean University of China, 2019)

Fengyun-3D MERSI True Color Imagery Developed for Environmental Applications - Xiuzhen Han; Feng Wang; Yang Han (Journal of Meteorological Research, 2019)

Effects of agricultural activities on the temporal variations of streamflow: trends and long memory - Chuke Chen; Yong Tian; You-Kuan Zhang; Xin He; Xiaofan Yang; Xiuyu Liang; Yi Zheng; Feng Han; Chunmiao Zheng; Chen Yang (Stochastic Environmental Research and Risk Assessment, 2019)

ULK1 affects cell viability of goat Sertoli cell by modulating both autophagy and apoptosis - Jing Pang; Le Han; Zifei Liu; Jian Zheng; Jie Zhao; Kaiping Deng; Feng Wang; Yanli Zhang (In Vitro Cellular & Developmental Biology - Animal, 2019)

Integrated analysis of RNA-seq and microRNA-seq depicts miRNA–mRNA networks involved in stripe patterns of Botia superciliaris skin - Jian Zhou; Han Zhao; Lu Zhang; Can Liu; Siyuan Feng; Jideng Ma; Qiang Li; Hongyu Ke; Xinyu Wang; Lingyan Liu; Chao Liu; Xutao Su; et al. (Functional & Integrative Genomics, 2019)

The impact and mechanism of quaternary ammonium compounds on the transmission of antibiotic resistance genes - Yue Han; Zhen-Chao Zhou; Lin Zhu; Yuan-Yuan Wei; Wan-Qiu Feng; Lan Xu; Yang Liu; Ze-Jun Lin; Xin-Yi Shuai; Zhi-Jian Zhang; Hong Chen (Environmental Science and Pollution Research, 2019)

Biochar promotes methane production at high acetate concentrations in anaerobic soils - Leilei Xiao; Fanghua Liu; Hengduo Xu; Dawei Feng; Jinchao Liu; Guangxuan Han (Environmental Chemistry Letters, 2019)

Behavioural, physiological and molecular changes in alloparental caregivers may be responsible for selection response for female reproductive investment in honey bees - Fan Wu; Chuan Ma; Bin Han; Lifeng Meng; Han Hu; Yu Fang; Mao Feng; Xufeng Zhang; Olav Rueppell; Jianke Li (Molecular Ecology, 2019)
Reproductive investment is a central life history variable that influences all aspects of life. Hormones coordinate reproduction in multicellular organisms, but the mechanisms controlling the collective reproductive investment of social insects are largely unexplored. One important aspect of honey bee ( Apis mellifera ) reproductive investment consists of raising female‐destined larvae into new queens by alloparental care of nurse bees in form of royal jelly provisioning. Artificial selection for commercial royal jelly production over 40 years has increased this reproductive investment by an order of magnitude. In a cross‐fostering experiment, we establish that this shift in social phenotype is caused by nurse bees. We find no evidence for changes in larval signalling. Instead, the antennae of the nurse bees of the selected stock are more responsive to brood pheromones than control bees. Correspondingly, the selected royal jelly bee nurses are more attracted to brood pheromones than unselected control nurses. Comparative proteomics of the antennae from the selected and unselected stocks indicate putative molecular mechanisms, primarily changes in chemosensation and energy metabolism. We report expression differences of several candidate genes that correlate with the differences in reproductive investment. The functional relevance of these genes is supported by demonstrating that the corresponding proteins can competitively bind one previously described and one newly discovered brood pheromone. Thus, we suggest several chemosensory genes, most prominently OBP16 and CSP4, as candidate mechanisms controlling queen rearing, a key reproductive investment, in honey bees. These findings reveal novel aspects of pheromonal communication in honey bees and explain how sensory changes affect communication and lead to a drastic shift in colony‐level resource allocation to sexual reproduction. Thus, pheromonal and hormonal communication may play similar roles for reproductive investment in superorganisms and multicellular organisms, respectively.

Indirect source apportionment of methyl mercaptan using CMB and PMF models: a case study near a refining and petrochemical plant - Jingjing Feng; Song Gao; Qingyan Fu; Xiaojia Chen; Xiaolin Chen; Demin Han; Jinping Cheng (Environmental Science and Pollution Research, 2019)

QTL mapping for maize starch content and candidate gene prediction combined with co-expression network analysis - Feng Lin; Ling Zhou; Bing He; Xiaolin Zhang; Huixue Dai; Yiliang Qian; Long Ruan; Han Zhao (Theoretical and Applied Genetics, 2019)

Proteomics analysis of Schwann cell-derived exosomes: a novel therapeutic strategy for central nervous system injury - Zhijian Wei; Baoyou Fan; Han Ding; Yang Liu; Haoshuai Tang; Dayu Pan; Jiaxiao Shi; Pengyuan Zheng; Hongyu Shi; Heng Wu; Ang Li; Shiqing Feng (Molecular and Cellular Biochemistry, 2019)

A Sustained Ocean Observing System in the Indian Ocean for Climate Related Scientific Knowledge and Societal Needs - J. C. Hermes; Y. Masumoto; L. M. Beal; M. K. Roxy; J. Vialard; M. Andres; H. Annamalai; S. Behera; N. D’Adamo; T. Doi; M. Feng; W. Han; et al. (Frontiers in Marine Science, 2019)

Distribution of lignin phenols in comparison with plant-derived lipids in the alpine versus temperate grassland soils - Shanshan Zhu; Guohua Dai; Tian Ma; Litong Chen; Dima Chen; Xiaotao Lü; Xiaobo Wang; Juntao Zhu; Yangjian Zhang; Yongfei Bai; Xingguo Han; Jin-Sheng He; et al. (Plant and Soil, 2019)

Petrocosmea qiruniae (Gesneriaceae), a new species from Guizhou, China with supplementary data and revised description of P. leiandra - Meng-Qi Han; Quan Yuan; Tian-Feng Lü; Li-Bing Zhang; Yan Liu (Kew Bulletin, 2019)

Biochar Effects on Bacterial Community and Metabolic Pathways in Continuously Cotton-Cropped Soil - Guangming Han; Quanqiu Chen; Shengxi Zhang; Guorong Li; Xianda Yi; Changhui Feng; Xiaogang Wang; Cui Yu; Jiayang Lan (Journal of Soil Science and Plant Nutrition, 2019)

Ambient air pollution and risk of type 2 diabetes in the Chinese - Hui Li; Donghui Duan; Jiaying Xu; Xiaoqi Feng; Thomas Astell-Burt; Tianfeng He; Guodong Xu; Jinshun Zhao; Lina Zhang; Dingyun You; Liyuan Han (Environmental Science and Pollution Research, 2019)

Identification of a lytic Pseudomonas aeruginosa phage depolymerase and its anti-biofilm effect and bactericidal contribution to serum - Liyuan Mi; Yannan Liu; Can Wang; Tongtong He; Shan Gao; Shaozhen Xing; Yong Huang; Hang Fan; Xianglilan Zhang; Wengong Yu; Zhiqiang Mi; Yigang Tong; et al. (Virus Genes, 2019)

Flaviflagellibacter deserti gen. nov., sp. nov., a novel member of the order Rhizobiales isolated from a desert soil - Lei Dong; Ming-Xian Han; Dong Wang; Feng Liu; Mipeshwaree Devi Asem; Jian-Yu Jiao; Min Xiao; Nimaichand Salam; Wen-Jun Li (Antonie van Leeuwenhoek, 2019)

Neuroprotective Influence of miR-301a Inhibition in Experimental Cerebral Ischemia/Reperfusion Rat Models Through Targeting NDRG2 - Tao Feng; Bang-Hua Han; Gong-Li Yang; Chao-Jie Shi; Zhen-Wen Gao; Ming-Zhi Cao; Xiao-Lei Zhu (Journal of Molecular Neuroscience, 2019)

Variations in dissolved inorganic carbon species in effluents from large-scale municipal wastewater treatment plants (Qingdao, China) and their potential impacts on coastal acidification - Xiang-Yu Liu; Xu-Feng Yang; Yun-Xiao Li; Han Zang; Long-Jun Zhang (Environmental Science and Pollution Research, 2019)

Epidemiological trends and virological traits of hepatitis B virus infection in pregnant women and neonates - Ting-Ting Peng; Qiu-E Cai; Min Yang; Shao-Ping Chen; Feng Chen; Miao Wang; Ling Peng; Gary Wong; Chen-Guang Shen; Wen-Bing Cheng; Sai-Yun Liu; Ya-Bai Peng; et al. (Archives of Virology, 2019)

Pathways Regulating Decreased Soil Respiration with Nitrogen Addition in a Subtropical Forest in China - Lizhuang Liang; Feng Chen; Hairong Han; Yanru Zhang; Jiang Zhu; Shukui Niu (Water, Air, & Soil Pollution, 2019)

Downregulation of the auxin transporter gene SlPIN8 results in pollen abortion in tomato - Zengyu Gan; Yi Feng; Ting Wu; Yi Wang; Xuefeng Xu; Xinzhong Zhang; Zhenhai Han (Plant Molecular Biology, 2019)

Probiotics ameliorate renal ischemia-reperfusion injury by modulating the phenotype of macrophages through the IL-10/GSK-3β/PTEN signaling pathway - Chenguang Ding; Feng Han; Heli Xiang; Yuxiang Wang; Yang Li; Jin Zheng; Wujun Xue; Xiaoming Ding; Puxun Tian (Pflügers Archiv - European Journal of Physiology, 2019)

Characterization and risk assessment of heavy metals in road dust from a developing city with good air quality and from Shanghai, China - Xiaojia Chen; Meixiu Guo; Jingjing Feng; Shan Liang; Deming Han; Jinping Cheng (Environmental Science and Pollution Research, 2019)

Calculation of an Adequate Intake (AI) Value and Safe Range of Selenium (Se) for Chinese Infants 0–3 Months Old Based on Se Concentration in the Milk of Lactating Chinese Women with Optimal Se Intake - Feng Han; Liping Liu; Jiaxi Lu; Yingjuan Chai; Jie Zhang; Shijin Wang; Licui Sun; Qin Wang; Yiqun Liu; Mengjie He; Weipeng Mu; Zhenwu Huang (Biological Trace Element Research, 2019)

Nitrogen addition does not reduce the role of spatial asynchrony in stabilising grassland communities - Yunhai Zhang; Jinchao Feng; Michel Loreau; Nianpeng He; Xingguo Han; Lin Jiang (Ecology Letters, 2019)
While nitrogen (N) amendment is known to affect the stability of ecological communities, whether this effect is scale‐dependent remains an open question. By conducting a field experiment in a temperate grassland, we found that both plant richness and temporal stability of community biomass increased with spatial scale, but N enrichment reduced richness and stability at the two scales considered. Reduced local‐scale stability under N enrichment arose from N‐induced reduction in population stability, which was partly attributable to the decline in local species richness, as well as reduction in asynchronous local population dynamics across species. Importantly, N enrichment did not alter spatial asynchrony among local communities, which provided similar spatial insurance effects at the larger scale, regardless of N enrichment levels. These results suggest that spatial variability among local communities, in addition to local diversity, may help stabilise ecosystems at larger spatial scales even in the face of anthropogenic environmental changes.

Changes in global monsoon precipitation and the related dynamic and thermodynamic mechanisms in recent decades - Zixuan Han; Tao Su; Bicheng Huang; Taichen Feng; Shulin Qu; Guolin Feng (International Journal of Climatology, 2019)
The aim of this study is to explore the long‐term trends in the distribution of global monsoon precipitation over recent decades using the Global Precipitation Climatology Project (GPCP) data set. In addition, the potential4 mechanisms are examined by applying the atmospheric moisture budget decomposition method to the outputs from the ERA‐Interim medium‐range weather forecasting reanalysis produced by the European Centre for Medium‐Range Weather Forecasts (ECMWF). Changes in global monsoon precipitation are primarily thermodynamically caused by changes in specific humidity and dynamically caused by changes in circulation, as well as by changes in moisture transport that are driven by transient eddies and local evaporation. The results show that the increasing trends in global summer monsoon precipitation from 1979 to 2016 were dominated by contributions from the southern Asian, South African, and North American monsoon regions and were driven by the response of atmospheric circulation to the enhanced east–west thermal contrast in the tropical Pacific. We find that changes in the sea surface temperature (SST) patterns promote increased low‐level vertical velocities in monsoon regions, leading to moisture convergence through divergent circulation anomalies when combined with the climatological humidity field. Hence, the processes result in increasing trends in monsoon precipitation. In addition, evaporation makes increasing contributions to monsoon precipitation throughout the world, except in the South American monsoon region. Moreover, subtropical regions in the East Pacific (the Atlantic) may be major sources of water vapour that have supported increases in precipitation over the southern Asian and North American monsoon regions (the South African monsoon region) in recent decades.

Extracellular ATP released by copper stress could act as diffusible signal in alleviating the copper stress-induced cell death - Ling-Yun Jia; Jing-Yue Bai; Kun Sun; Rong-fang Wang; Han-Qing Feng (Protoplasma, 2019)

The links between potassium availability and soil exchangeable calcium, magnesium, and aluminum are mediated by lime in acidic soil - Tianfu Han; Andong Cai; Kailou Liu; Jing Huang; Boren Wang; Dongchu Li; Muhammad Qaswar; Gu Feng; Huimin Zhang (Journal of Soils and Sediments, 2019)

Investigate the impact of local iron–steel industrial emission on atmospheric mercury concentration in Yangtze River Delta, China - Deming Han; Qingyan Fu; Song Gao; Xufeng Zhang; Jingjing Feng; Xiaolin Chen; Xiqian Huang; Haoxiang Liao; Jinping Cheng; Wenhua Wang (Environmental Science and Pollution Research, 2019)

A Context-Based Analgesia Model in Rats: Involvement of Prefrontal Cortex - Lingchi Xu; Yalan Wan; Longyu Ma; Jie Zheng; Bingxuan Han; Feng-Yu Liu; Ming Yi; You Wan (Neuroscience Bulletin, 2018)

Discovery of novel antagonists on β2-adrenoceptor from natural products using a label-free cell phenotypic assay - Pengyu Zhang; Jixia Wang; Ying Zhao; Xiuli Zhang; Lala Qu; Chaoran Wang; Jiatao Feng; Anhui Wang; Weijia Zhou; Yanfang Liu; Tao Hou; Han Zhou; et al. (Naunyn-Schmiedeberg's Archives of Pharmacology, 2018)

LaMIR166a-mediated auxin biosynthesis and signalling affect somatic embryogenesis in Larix leptolepis - Zhe-Xin Li; Yan-Ru Fan; Shao-Fei Dang; Wan-Feng Li; Li-Wang Qi; Su-ying Han (Molecular Genetics and Genomics, 2018)

Evaluation of the RPC Model for Ziyuan-3 Three-line Array Imagery - Zhonghua Hong; Shengyuan Xu; Yun Zhang; Yanling Han; Yongjiu Feng (Journal of the Indian Society of Remote Sensing, 2018)

The complete mitochondrial genome of the blue king crab, Paralithodes platypus (Decapoda: Lithodidae) - Li Feng; Jiao Yang; Qing-Yu Han; Gui-Fang Zhao (Conservation Genetics Resources, 2018)

Transcriptomic analysis of porcine PBMCs in response to Actinobacillus pleuropneumoniae reveals the dynamic changes of differentially expressed genes related to immuno-inflammatory responses - Hexiang Jiang; Rining Zhu; Hongtao Liu; Chuntong Bao; Jianfang Liu; Abdalla Eltahir; Paul R. Langford; Diangang Sun; Zhonghua Liu; Changjiang Sun; Jingmin Gu; Wenyu Han; et al. (Antonie van Leeuwenhoek, 2018)

Adjusting precipitation measurements from the TRwS204 automatic weighing gauge in the Qilian Mountains, China - Qin Zheng; Ren-sheng Chen; Chun-tan Han; Jun-feng Liu; Yao-xuan Song; Zhang-wen Liu; Yong Yang; Lei Wang; Xi-qiang Wang; Xiao-jiao Liu; Shu-hai Guo; Guo-hua Liu (Journal of Mountain Science, 2018)

Ultrarapid Inductive Rewarming of Vitrified Biomaterials with Thin Metal Forms - Navid Manuchehrabadi; Meng Shi; Priyatanu Roy; Zonghu Han; Jinbin Qiu; Feng Xu; Tian Jian Lu; John Bischof (Annals of Biomedical Engineering, 2018)

Poor agreement between repeated T-SPOT.TB in a short time period in a high TB burden country - Feng Shen; Chao Han; Mao-Shui Wang; Yu He (Infectious Diseases, 2018)

Prenylated flavonoids and dihydrophenanthrenes from the leaves of Epimedium brevicornu and their cytotoxicity against HepG2 cells - Xu Pang; Shuang-Shuang Yin; Hai-Yang Yu; Yi Zhang; Tao Wang; Li-Min Hu; Li-Feng Han (Natural Product Research, 2018)

Human Cutaneous Protothecosis: A Case Report and Review of Cases from Mainland China, Hong Kong, and Taiwan - Fang Wang; Peiying Feng; Yimin Lin; Xiaohong Chen; Dandan Xu; Zhuo Wang; Jiande Han (Mycopathologia, 2018)

Macleaya cordata helps improve the growth-promoting effect of chlortetracycline on broiler chickens - Bin Li; Jin-qiu Zhang; Xian-gan Han; Zheng-lei Wang; Yuan-yuan Xu; Jin-feng Miao (Journal of Zhejiang University-SCIENCE B, 2018)

Crystal structure of Arabidopsis thaliana glutamyl-tRNAGlu reductase in complex with NADPH and glutamyl-tRNAGlu reductase binding protein - Aiguo Zhao; Feng Han (Photosynthesis Research, 2018)

Proteomics analysis reveals marker proteins for minor vein initiation in rice leaf - Dan Feng; Yanwei Wang; Tiegang Lu; Zhiguo Zhang; Xiao Han (Functional & Integrative Genomics, 2018)

Coupling and decoupling effects of agricultural carbon emissions in China and their driving factors - Haibin Han; Zhangqi Zhong; Yu Guo; Feng Xi; Shuangliang Liu (Environmental Science and Pollution Research, 2018)

Efficient mercury recovery from mercuric-thiosulfate solutions by ultraviolet photolysis - Wei Wang; Chao Han; Feng Xie (Environmental Chemistry Letters, 2018)

Prognostic significance of combining high mobility group Box-1 and OV-6 expression in hepatocellular carcinoma - Jihui Zhu; Han Yu; Shuzhen Chen; Pinghua Yang; Zihui Dong; Yan Ling; Hao Tang; Shilei Bai; Wen Yang; Liang Tang; Feng Shen; Hongyang Wang; et al. (Science China Life Sciences, 2018)

Neonatal Exposure to Low-Dose (1.2%) Sevoflurane Increases Rats’ Hippocampal Neurogenesis and Synaptic Plasticity in Later Life - Xi Chen; Xue Zhou; Lu Yang; Xu Miao; Di-Han Lu; Xiao-Yu Yang; Zhi-Bin Zhou; Wen-Bin Kang; Ke-Yu Chen; Li-Hua Zhou; Xia Feng (Neurotoxicity Research, 2018)

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress - Qiao Huang; Meiling Sun; Mei Li; Dingmei Zhang; Feng Han; Jun Chao Wu; Kohji Fukunaga; Zhong Chen; Zheng-Hong Qin (Molecular Neurobiology, 2018)

A novel strategy for water disinfection with a AgNPs/gelatin sponge filter - Feng Wei; Xiaole Zhao; Chao Li; Xiaojun Han (Environmental Science and Pollution Research, 2018)

Risk factors, outcomes and genotypes of carbapenem-nonsusceptible Klebsiella pneumoniae bloodstream infection: a three-year retrospective study in a large tertiary hospital in Northern China - Si-Han Zheng; Sheng-Ji Cao; Hui Xu; Dan Feng; Li-Ping Wan; Guang-Jie Wang; Xiao-Guang Xiao (Infectious Diseases, 2018)

D-Cycloserine Ameliorates Autism-Like Deficits by Removing GluA2-Containing AMPA Receptors in a Valproic Acid-Induced Rat Model - Han-Fang Wu; Po See Chen; Ya-Ting Hsu; Chi-Wei Lee; Tzu-Feng Wang; Yi-Ju Chen; Hui-Ching Lin (Molecular Neurobiology, 2018)

Umbilical Cord Mesenchymal Stem Cells Conditioned Medium Promotes Aβ25-35 phagocytosis by Modulating Autophagy and Aβ-Degrading Enzymes in BV2 Cells - Zhihao Xu; Wenbin Nan; Xiaoyue Zhang; Yuliang Sun; Jichao Yang; Kecheng Lu; Yalin Liu; Yaoxin Gao; Fen Yang; Wenchao Mao; Xuekun Xing; Jiang Du; et al. (Journal of Molecular Neuroscience, 2018)

Effluent concentration and removal efficiency of nine heavy metals in secondary treatment plants in Shanghai, China - Jingjing Feng; Xiaolin Chen; Lei Jia; Qizhen Liu; Xiaojia Chen; Deming Han; Jinping Cheng (Environmental Science and Pollution Research, 2018)

Cortical thickness reductions associate with abnormal resting-state functional connectivity in non-neuropsychiatric systemic lupus erythematosus - Chen Niu; Xiangliang Tan; Xiaojin Liu; Kai Han; Meiqi Niu; Jun Xu; Ling Zhao; Yuankui Wu; Feng Deng; Qin Huang; Xiaoyan Wu; Huiyuan Huang; et al. (Brain Imaging and Behavior, 2018)

Genomic changes in an attenuated genotype I Japanese encephalitis virus and comparison with virulent parental strain - Yuyong Zhou; Rui Wu; Yao Feng; Qin Zhao; Xintian Wen; Xiaobo Huang; Yiping Wen; Qigui Yan; Yong Huang; Xiaoping Ma; Xinfeng Han; Sanjie Cao (Virus Genes, 2018)

Isolation and identification of Salmonella pullorum bacteriophage YSP2 and its use as a therapy for chicken diarrhea - Kunyuan Tie; Yuyu Yuan; Shiqing Yan; Xi Yu; Qiuyang Zhang; Huihui Xu; Yang Zhang; Jingmin Gu; Changjiang Sun; Liancheng Lei; Wenyu Han; Xin Feng (Virus Genes, 2018)