Association of cognitive impairment and reduced cortical thickness in prefrontal cortex and anterior cingulate cortex with treatment-resistant depression - Mu-Hong Chen; Wan-Chen Chang; Pei-Chi Tu; Wei-Chen Lin; Cheng-Ta Li; Wen-Sheng Huang; Ya-Mei Bai; Shih-Jen Tsai; Tung-Ping Su (Brain Imaging and Behavior, 2022)

Short-term effect of sulfur dioxide (SO2) change on the risk of tuberculosis outpatient visits in 16 cities of Anhui Province, China: the first multi-city study to explore differences in occupational patients - Xin-Qiang Wang; Jia-Wen Zhao; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Ying-Qing Li; Xin Cheng; Zhen-Hua Li; Yi-Cheng Mao; Cheng-Yang Hu; Kai Huang; Kun Ding; et al. (Environmental Science and Pollution Research, 2022)

A Non-destructive Quantitative Transmission Raman Spectroscopy Method for Active Pharmaceutical Ingredient in Drug Product In-Use Samples Prepared in Dosing Vehicles - Gregory Doddridge; Edwin Hong; David Cheng Thiam Tan; Yemin Liu (AAPS PharmSciTech, 2022)

Correction to: Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines - Hong-Chieh Tsai; Kuo-Chen Wei; Pin-Yuan Chen; Chiung-Yin Huang; Ko-Ting Chen; Ya-Jui Lin; Hsiao-Wei Cheng; Chun-Hao Huang; Hsiang-Tsui Wang (NeuroMolecular Medicine, 2022)

Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines - Hong-Chieh Tsai; Kuo-Chen Wei; Pin-Yuan Chen; Chiung-Yin Huang; Ko-Ting Chen; Ya-Jui Lin; Hsiao-Wei Cheng; Chun-Hao Huang; Hsiang-Tsui Wang (NeuroMolecular Medicine, 2022)

Multiple Protein Subcellular Locations Prediction Based on Deep Convolutional Neural Networks with Self-Attention Mechanism - Hanhan Cong; Hong Liu; Yi Cao; Yuehui Chen; Cheng Liang (Interdisciplinary Sciences: Computational Life Sciences, 2022)

Prediction of disability-free survival in healthy older people - Johannes Tobias Neumann; Le T. P. Thao; Anne M. Murray; Emily Callander; Prudence R. Carr; Mark R. Nelson; Rory Wolfe; Robyn L. Woods; Christopher M. Reid; Raj C. Shah; Anne B. Newman; Jeff D. Williamson; et al. (GeroScience, 2022)
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disability-free survival outcome was defined as absence of dementia, persistent disability or death. Selection of potential predictors from amongst 25 biomedical, psychosocial and lifestyle variables including recognized geriatric risk factors, utilizing a machine-learning approach. Separate models were developed for men and women. The selected predictors were evaluated in a multivariable Cox proportional hazards model and validated internally by bootstrapping. We included 19,114 Australian and US participants aged ≥65 years (median 74 years, IQR 71.6–77.7). Common predictors of a worse prognosis in both sexes included higher age, lower Modified Mini-Mental State Examination score, lower gait speed, lower grip strength and abnormal (low or elevated) body mass index. Additional risk factors for men included current smoking, and abnormal eGFR. In women, diabetes and depression were additional predictors. The biased-corrected areas under the receiver operating characteristic curves for the final prognostic models at 5 years were 0.72 for men and 0.75 for women. Final models showed good calibration between the observed and predicted risks. We developed a prediction model in which age, cognitive function and gait speed were the strongest predictors of disability-free survival in healthy older people. Trial registration Clinicaltrials.gov (NCT01038583)

Short-term effects and economic burden assessment of ambient air pollution on hospitalizations for schizophrenia - Yanhu Ji; Bin Liu; Jian Song; Rubing Pan; Jian Cheng; Heng Wang; Hong Su (Environmental Science and Pollution Research, 2022)

Estrogen Deficiency Aggravates Fluoride-Induced Liver Damage and Lipid Metabolism Disorder in Rats - Ya-ming Yu; Bian-hua Zhou; Yi-lin Yang; Cheng-Xiang Guo; Jing Zhao; Hong-wei Wang (Biological Trace Element Research, 2022)

Flow-slide characteristics and failure mechanism of shallow landslides in granite residual soil under heavy rainfall - Hui-lin Bai; Wen-kai Feng; Shuang-quan Li; Long-zhen Ye; Zhong-teng Wu; Rui Hu; Hong-chuan Dai; Yun-peng Hu; Xiao-yu Yi; Peng-cheng Deng (Journal of Mountain Science, 2022)

Community Competition Is the Microorganism Feedback to Sedimentary Carbon Degradation Process in Aquaculture Tidal Flats - Min Zhou; Fu-Tao Fang; Cong Zeng; Li-Hong Zhang; Cheng-Xu Zhou; Zhuo-Yi Zhu (Frontiers in Marine Science, 2022)
How the microbial community response to carbon degradation is unclear, while it plays an essential role in predicting microbial community shift and determining carbon cycling. Surface sediments in two contrasting aquacultural tidal flat sites in Fujian Province, China, were collected in October, 2020. In addition to 16s rRNA gene high-throughput sequencing for determining bacteria and archaea biodiversity, an amino acids-based molecular degradation index DI was used to quantify the carbon degradation status. The results revealed that the microorganism response to DI at the family level was community competition. Specifically, the winning microbes that grew under carbon degradation (i.e., operational taxa unit numbers negatively related with the degradation index) accounted for only 18% of the total family number, but accounted for 54% of the total operational taxa unit numbers. Network analysis confirmed the oppressive relation between winners and the rest (losers + centrists), and further suggested the losers survival strategy as uniting the centrists. These findings shed new light on microorganism feedback to carbon degradation, and provide a scientific basis for the explanation of microbial community shift under progressive carbon degradation.

Two New Species and One New Genus of Glass Sponges (Hexactinellida: Euplectellidae and Euretidae), From a Transect on a Seamount in the Northwestern Pacific Ocean - Chengcheng Shen; Hong Cheng; Dongsheng Zhang; Chunsheng Wang (Frontiers in Marine Science, 2022)
Hexactinellid sponges often form structural habitats for other organisms and thus support high biodiversity. Two representative morphotypes of hexactinellid sponges were sampled by a remotely operated vehicle along a transect (depths of 2377–2758 m) on the Ko-Hakucho Guyot in the northwestern Pacific Ocean, both new to science. One new species, Flavovirens hemiglobus gen. et sp. nov., which is pedunculate and bears the main choanosomal spicules of diactins, is clearly attributed to the euplectellid subfamily Bolosominae. Its set of microscleres present (namely, predominating oxyhexasters and discasters, and rare discohexasters and staurodiscs) characterizes it as a new genus. The other new species, Chonelasma tyloscopulatum sp. nov., which is funnel in form without dichotomous branching tubes or lateral oscula and has firm body walls supported by a three-layered dictyonal framework, is clearly attributed to the euretid genus Chonelasma (subfamily Chonelasmatinae). Its presence of surface pentactins, two types of scopules, and both oxy- and disco-tipped hexasters or hemihexasters as common microscleres, characterizes it as a new species. The placements are also supported by molecular phylogenetic evidence from nuclear 18S rDNA and 28S rDNA, and mitochondrial 16S rDNA and cytochrome c oxidase subunit I (COI) gene. More sampling efforts should be conducted to improve the understanding of the biodiversity of deep-sea seamount sponges.

Impact of the evolution of Plateau Lake landscape pattern on ecosystem service value in the Pearl River basin: a case study of Yilong Lake Basin in Yunnan Province, China - Guoqiang Ma; Jianping Xiao; Qiujie Li; Lixun Zhang; Bei An; Guojun Sun; Hua Cheng; Jiaqi Tang; Hong Li (Acta Geophysica, 2022)

Fishery Resources, Ecological Environment Carrying Capacity Evaluation and Coupling Coordination Analysis: The Case of the Dachen Islands, East China Sea - Hong Huang; Zuanyi Wang; Yingdong Li; Xu Zhao; Zhenhua Wang; Xiaopeng Cheng (Frontiers in Marine Science, 2022)
Impacts of human activity on the sustainable development of marine fisheries have been greatly concerned, and the carrying capacity with theoretic and practical meanings has become a focused area over the past two decades. More importantly, there are few studies on the fishery resources and environment compound system. In this study, based on the investigation data in Dachen Islands during 2019–2021, we proposed the evaluation method of fishery resources and ecological environment carrying capacity (FRCC & MEECC) and analyzed the coupling coordination degree between the fishery resources and environment. The results showed that (1) the MEECC of Dachen Islands was in the critical overload state and fluctuated significantly among seasons and the winter voyage of 2021 was the worst. (2) The nekton index of Dachen Islands was basically stable, the fish eggs and juvenile index dropped markedly, and the FRCC was also critically overloaded. (3) The fishery resources and marine environment were moderately balanced. Further, the development was relatively synchronized in autumn of 2019 and 2020, while the fishery resources in spring of 2021 lagged behind the marine environment.

A deep learning-based approach to automatic proximal femur segmentation in quantitative CT images - Yu Deng; Ling Wang; Chen Zhao; Shaojie Tang; Xiaoguang Cheng; Hong-Wen Deng; Weihua Zhou (Medical & Biological Engineering & Computing, 2022)

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight - Yu-Qian Song; Shi-Di Hu; Xu Lin; Xiang-He Meng; Xiao Wang; Yin-Hua Zhang; Cheng Peng; Rui Gong; Tao Xu; Tong Zhang; Chen-Zhong Li; Dao-Yan Pan; et al. (Journal of Molecular Medicine, 2022)
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibility variants shared between these two traits. We detected 5 novel potential pleiotropic loci which are located at or near 7 different genes ( NTAN1 , PDXDC1 , CACNA1G , JAG1 , FAT1P1 , CCDC170 , ESR1 ), among which PDXDC1 and FAT1P1 have not previously been linked to these phenotypes. To partially validate the findings, we demonstrated that the expression of PDXDC1 was dramatically reduced in ovariectomized (OVX) mice in comparison with sham-operated (SHAM) mice in both the growth plate and trabecula bone. Furthermore, immunohistochemistry assay with serial sections showed that both osteoclasts and osteoblasts express PDXDC1 , supporting its potential role in bone metabolism. In conclusion, our study provides insights into some shared genetic mechanisms for BMD and BW as well as a novel potential therapeutic target for the prevention of OP in the early stages of the disease development. Key messages We investigated pleiotropy-informed enrichment between LS BMD and BW. We identified genetic variants related to both LS BMD and BW by utilizing a cFDR approach. PDXDC1 is a novel pleiotropic gene which may be related to both LS BMD and BW. Elevated expression of PDXDC1 is related to higher BMD and lower ratio n-6/n-3 PUFA indicating a bone protective effect of PDXDC1.

Quantitative detection of parasitic ciliate Cryptocaryon irritans in seawater with an optimized sample processing method - Jia‐Jia Tang; Zhi‐Hong Zhong; Zhi‐Cheng Li; Qing‐Kai Guo; Shi‐Yu Li; Yi‐Xuan Guo; Biao Jiang; An‐Xing Li (Journal of Fish Diseases, 2022)
The protozoan Cryptocaryon irritans is one of the most important ectoparasites of marine fish, causing ‘white spot disease’ and mass mortality in aquaculture. To accurately predict disease outbreaks and develop prevention strategies, improved detection methods are required that are sensitive, convenient and rapid. In this study, a pair of specific primers based on the C . irritans 18S rRNA gene was developed and used in a real‐time PCR (qPCR) assay. This assay was able to detect five theronts in 1 L of natural seawater. Furthermore, a linear model was established to analyse the log of Ct value and parasite abundance in seawater (y = –2.9623x + 24.2930), and the coefficient of determination (R 2 ) value was 0.979. A lysis buffer was optimized for theront DNA extraction and used for storage sample. This method was superior to the commercial water DNA kit, and there was no significant degradation of DNA at room temperature for 24–96 hr. A dilution method was developed to manage qPCR inhibitors and used to investigate natural seawater samples in a net cage farm with diseased fish, and the findings were consistent with the actual situation. This study provides a valuable tool for assisting in the early monitoring and control of cryptocaryoniasis in aquaculture.

Berberisides A-D: three novel prenylated benzoic acid derivatives and a clerodane glycoside from Berberis tsarica aherndt. - Zhao-Yue Dong; Qing-Hong Zeng; Lin Wei; Xin Guo; Yan Sun; Fan-Cheng Meng; Guo-Wei Wang; Xiao-Zhong Lan; Zhi-Hua Liao; Min Chen (Natural Product Research, 2022)

Unique bacterial communities associated with components of an artificial aquarium ecosystem and their possible contributions to nutrient cycling in this microecosystem - Jun Shi Zhou; Jian Fei Cheng; Xue Dong Li; Yan Hong Li (World Journal of Microbiology and Biotechnology, 2022)

Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide - Ting Jiang; Geng Xia; Bo Yang; Hong-wei Zhang; Yue-shan Yin; Cheng-wei Tang; Jin-hui Yang (Tissue Engineering and Regenerative Medicine, 2022)
Background: Endotoxemia is related to worse clinical outcomes in acute liver failure (ALF), but its management remains unsatisfactory. In this study, we aimed to assess whether the application of bone marrow mesenchymal stem cells (BMSCs) could eliminate endotoxemia and protect rats against ALF induced by thioacetamide (TAA). Methods: BMSCs were isolated from rats and identified by the specific morphology, differentiation potential, and surface markers. The optimal dose of TAA for this study was explored and TAA-induced ALF rats were randomized to three groups: the normal control group (Saline), ALF group (TAA + Saline), and BMSCs-treated group (TAA + BMSCs). The intestinal migration and differentiation of BMSCs was tracked in vivo , and intestinal permeability, endotoxin and inflammatory cytokines, histology, and mortality were analyzed. Moreover, we added the inhibitor of the PI3K/AKT/mTOR signaling pathway into the co-culture system of BMSCs with enterocytes and then performed CK and Villin expression experiments to assess the role of PI3K/AKT/mTOR signal pathway in the intestinal differentiation of BMSCs. Results: BMSCs migrated to the intestinal injury sites and differentiated into enterocytes, intestinal permeability was decreased compared with the ALF group. The higher expression of endotoxin and inflammatory cytokines were reversed after BMSCs transplantation in rats with ALF. Mortality and intestinal lesion were significantly decreased. Blocking the PI3K/AKT/mTOR signal pathway inhibited BMSCs’ intestinal differentiation in vitro . Conclusion: BMSCs can eliminate endotoxemia and reduce mortality in rats with ALF, and the PI3K/AKT/mTOR signal pathway is involved in intestinal differentiation. BMSCs transplantation could be a potential candidate for the treatment of endotoxemia in ALF.

Efficient genetic transformation and CRISPR/Cas9-mediated genome editing of watermelon assisted by genes encoding developmental regulators - Wenbo Pan; Zhentao Cheng; Zhiguo Han; Hong Yang; Wanggen Zhang; Huawei Zhang (Journal of Zhejiang University-SCIENCE B, 2022)

Subcellular localization and identification of acyl-CoA: lysophosphatidylethanolamine acyltransferase (LPEAT) in the arachidonic acid-rich green microalga, Myrmecia incisa Reisigl - Yi Liu; Hong Bao; Mei-Li Zhu; Cheng-Xi Hu; Zhi-Gang Zhou (Journal of Applied Phycology, 2022)

Alternaria species causing leaf spot on hemp (Cannabis sativa) in Northern China - Hong Cheng; Lin Zhao; Xin Wei; Xi Liu; Guo-Yang Gao; Jian-Xin Deng; Mei-Jia Li (European Journal of Plant Pathology, 2022)

Short-term effect of ambient air pollutant change on the risk of tuberculosis outpatient visits: a time-series study in Fuyang, China - Xin-Qiang Wang; Ying-Qing Li; Cheng-Yang Hu; Kai Huang; Kun Ding; Xiao-Jing Yang; Xin Cheng; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Yong-Zhong Zhang; Zhen-tao Ding; et al. (Environmental Science and Pollution Research, 2022)

Novel bioavailability-based risk assessment of Cd in earthworms and leeches utilizing in vitro digestion/Caco-2 and MDCK cells - Tian-tian Zuo; Fei-ya Luo; Huai-zhen He; Hong-yu Jin; Lei Sun; Shu-xia Xing; Bo Li; Fei Gao; Shuang-cheng Ma; Lang-chong He (Environmental Science and Pollution Research, 2022)

Extensive sequence divergence between the reference genomes of Taraxacum kok-saghyz and Taraxacum mongolicum - Tao Lin; Xia Xu; Huilong Du; Xiuli Fan; Qingwen Chen; Chunyan Hai; Zijian Zhou; Xiao Su; Liquan Kou; Qiang Gao; Lingwei Deng; Jinsheng Jiang; et al. (Science China Life Sciences, 2022)

Association between maternal exposure to PM10 and risk of anorectal atresia/stenosis in offspring: a population-based case-control study in Liaoning Province, China - Tie-Ning Zhang; Qi-Jun Wu; Yan-Hong Huang; Jing Li; Zong-Jiao Chen; Li-Li Li; Yan-Ling Chen; Shu Liu; Cheng-Zhi Jiang; Yu-Hong Zhao (Environmental Science and Pollution Research, 2022)

Effects of extreme precipitation on hospitalization risk and disease burden of schizophrenia in urban and rural Lu’an, China, from 2010 to 2019 - Yudong Wu; Zhenghai Yao; Gongyan Ma; Jian Cheng; Huabin Xu; Wei Qin; Weizhuo Yi; Rubing Pan; Qiannan Wei; Chao Tang; Xiangguo Liu; Yangyang He; et al. (Environmental Science and Pollution Research, 2022)

Description of two nitrogen-fixing bacteria, Geomonas fuzhouensis sp. nov. and Geomonas agri sp. nov., isolated from paddy soils - Shang Yang; Guo-Hong Liu; Rong Tang; Shuang Han; Cheng-Jie Xie; Shun-Gui Zhou (Antonie van Leeuwenhoek, 2022)

MoOpy2 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae - Ying‐Ying Cai; Jing‐Yi Wang; Xi‐Yu Wu; Shuang Liang; Xue‐Ming Zhu; Lin Li; Jian‐Ping Lu; Xiao‐Hong Liu; Fu‐Cheng Lin (Environmental Microbiology, 2022)
Summary The development and pathogenicity of the fungus Magnaporthe oryzae , the causal agent of destructive rice blast disease, require it to perceive external environmental signals. Opy2, an overproduction‐induced pheromone‐resistant protein 2, is a crucial protein for sensing external signals in Saccharomyces cerevisiae . However, the biological functions of the homologue of Opy2 in M. oryzae are unclear. In this study, we identified that MoOPY2 is involved in fungal development, pathogenicity, and autophagy in M. oryzae . Deletion of MoOPY2 resulted in pleiotropic defects in hyphal growth, conidiation, germ tube extension, appressorium formation, appressorium turgor generation, and invasive growth, therefore leading to attenuated pathogenicity. Furthermore, MoOpy2 participates in the Osm1 MAPK pathway and the Mps1 MAPK pathway by interacting with the adaptor protein Mst50. The interaction sites of Mst50 and MoOpy2 colocalized with the autophagic marker protein MoAtg8 in the preautophagosomal structure sites (PAS). Notably, the Δ Moopy2 mutant caused cumulative MoAtg8 lipidation and rapid GFP‐MoAtg8 degradation in response to nitrogen starvation, showing that MoOpy2 is involved in the negative regulation of autophagy activity. Taken together, our study revealed that MoOpy2 of M. oryzae plays an essential role in the orchestration of fungal development, appressorium penetration, autophagy and pathogenesis.

Endosomal sorting complexes required for transport‐0 ( ESCRT ‐0) are essential for fungal development, pathogenicity, autophagy and ER ‐phagy in Magnaporthe oryzae - Li‐Xiao Sun; Hui Qian; Meng‐Yu Liu; Ming‐Hua Wu; Yun‐Yun Wei; Xue‐Ming Zhu; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2022)
Summary Magnaporthe oryzae is an important plant pathogen that causes rice blast. Hse1 and Vps27 are components of ESCRT‐0 involved in the multivesicular body (MVB) sorting pathway and biogenesis. To date, the biological functions of ESCRT‐0 in M. oryzae have not been determined. In this study, we identified and characterized Hse1 and Vps27 in M. oryzae . Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves. Disruption of MoHse1 and MoVps27 triggered increased lipidation of MoAtg8 and degradation of GFP‐MoAtg8, indicating that ESCRT‐0 is involved in the regulation of autophagy. ESCRT‐0 was determined to interact with coat protein complex II (COPII), a regulator functioning in homeostasis of the endoplasmic reticulum (ER homeostasis), and disruption of MoHse1 and MoVps27 also blocked activation of the unfolded protein response (UPR) and autophagy of the endoplasmic reticulum (ER‐phagy). Overall, our results indicate that ESCRT‐0 plays critical roles in regulating fungal development, virulence, autophagy and ER‐phagy in M. oryzae .

Prevalence, complete genome, and metabolic potentials of a phylogenetically novel cyanobacterial symbiont in the coral‐killing sponge, Terpios hoshinota - Yu‐Hsiang Chen; Hsing‐Ju Chen; Cheng‐Yu Yang; Jia‐Ho Shiu; Daphne Z. Hoh; Pei‐Wen Chiang; Wenhua Savanna Chow; Chaolun Allen Chen; Tin‐Han Shih; Szu‐Hsien Lin; Chi‐Ming Yang; James Davis Reimer; et al. (Environmental Microbiology, 2022)
Summary Terpios hoshinota is an aggressive, space‐competing sponge that kills various stony corals. Outbreaks of this species have led to intense damage to coral reefs in many locations. Here, the first large‐scale 16S rRNA gene survey across three oceans revealed that bacteria related to the taxa Prochloron , Endozoicomonas , SAR116, Ruegeria , and unclassified Proteobacteria were prevalent in T . hoshinota . A Prochloron ‐related bacterium was the most dominant and prevalent cyanobacterium in T . hoshinota . The complete genome of this uncultivated cyanobacterium and pigment analysis demonstrated that it has phycobiliproteins and lacks chlorophyll b , which is inconsistent with the definition of Prochloron . Furthermore, the cyanobacterium was phylogenetically distinct from Prochloron , strongly suggesting that it should be a sister taxon to Prochloron . Therefore, we proposed this symbiotic cyanobacterium as a novel species under the new genus Candidatus Paraprochloron terpiosi. Comparative genomic analyses revealed that ‘Paraprochloron’ and Prochloron exhibit distinct genomic features and DNA replication machinery. We also characterized the metabolic potentials of ‘Paraprochloron terpiosi’ in carbon and nitrogen cycling and propose a model for interactions between it and T. hoshinota . This study builds a foundation for the study of the T . hoshinota microbiome and paves the way for better understanding of ecosystems involving this coral‐killing sponge.

Design, synthesis and agricultural evaluation of derivatives of N-Acyl-N-(m-fluoro-benzyl)-6-amino-coumarin - Yan Jin; Yin-hao Ding; Jing-jing Dong; Yan Wei; Shuang-hong Hao; Bai-cheng Feng (Natural Product Research, 2022)

Galectin-1 Contributes to Vascular Remodeling and Blood Flow Recovery After Cerebral Ischemia in Mice - Yin-hong Cheng; Yi-fan Jiang; Chuan Qin; Ke Shang; Yuan Yuan; Xian-jie Wei; Zhe Xu; Xiang Luo; Wei Wang; Wen-sheng Qu (Translational Stroke Research, 2022)

circSVIL regulates bovine myoblast development by inhibiting STAT1 phosphorylation - Binglin Yue; Haiyan Yang; Jiyao Wu; Jian Wang; Wenxiu Ru; Jie Cheng; Yongzheng Huang; Xianyong Lan; Chuzhao Lei; Hong Chen (Science China Life Sciences, 2022)

Effects of Axial Air Deck on Blast-Induced Ground Vibration - Ruishan Cheng; Zilong Zhou; Wensu Chen; Hong Hao (Rock Mechanics and Rock Engineering, 2022)

Melatonin secretion, molecular expression and evolution of MT1/2 in two Lasiopodomys species - Hong Sun; Dan Pan; Denghui Liu; Yuyang Cheng; Yifeng Zhang; Zhenlong Wang (Mammalian Biology, 2022)

Identifying the drivers of changes in embodied food–energy–water in the Bohai mega-urban region, China: A perspective of final demands - Caiyun Deng; Hongrui Wang; Siyang Hong; Weijing Zhao; Cheng Wang (Environmental Science and Pollution Research, 2022)

Effects of cryopreservation on the ultrastructure of coral larvae - Luca Cirino; Sujune Tsai; Li-Hsueh Wang; Wen-Chung Hsieh; Cheng-Liang Huang; Zhi-Hong Wen; Chiahsin Lin (Coral Reefs, 2022)

PI3K/Akt Signaling Pathway Ameliorates Oxidative Stress-Induced Apoptosis upon Manganese Exposure in PC12 Cells - Yanli Tan; Hong Cheng; Cheng Su; Pan Chen; Xiaobo Yang (Biological Trace Element Research, 2022)

A Physics-Informed Neural Network for the Prediction of Unmanned Surface Vehicle Dynamics - Peng-Fei Xu; Chen-Bo Han; Hong-Xia Cheng; Chen Cheng; Tong Ge (Journal of Marine Science and Engineering, 2022)
A three-degrees-of-freedom model, including surge, sway and yaw motion, with differential thrusters is proposed to describe unmanned surface vehicle (USV) dynamics in this study. The experiment is carried out in the Qing Huai River and the data obtained from different zigzag trajectories are filtered by a Gaussian filtering method. A physics-informed neural network (PINN) is proposed to identify the dynamic models of the USV. PINNs combine the advantages of data-driven machine learning and physical models. They can also embed the speed and steering models into the loss function, which can significantly retain all types of information. Compared with traditional neural networks, the results show that the PINN has better generalization ability in predicting the surge and sway velocities and rotation speed with only limited training data.

Distribution of Coomassie Blue Stainable Particles in the Pearl River Estuary, China, Insight Into the Nitrogen Cycling in Estuarine System - Cui-Ci Sun; Wei-Zhong Yue; You-Shao Wang; Wei-Hong He; Yi-Guo Hong; Fu-Lin Sun; Hao Cheng; Mei-Lin Wu; Zhao-Yu Jiang; Fei Jiao; Yu-Tu Wang (Frontiers in Marine Science, 2022)
Distributions of Coomassie Blue stainable particles (CSP), the sources and transports, as well as their implications for nitrogen biogeochemical cycles in the Pearl River estuary (PRE) were investigated during two cruises in August 2016 and January 2017. CSP color concentrations (CSP concentration determined spectrophotometrically) were 73.7–685.3 μg BSA eq L –1 [μg Bovine serum albumin (BSA) equivalent liter –1 ] in August 2016 and 100.6–396.4 μg BSA eq L –1 in January 2017, respectively. CSP concentrations were high in low-salinity waters (<5), and declined from the river to the middle estuary by 80% in the wet season and 55.6% in the dry season, respectively, then increased again in the lower estuary due to high primary production. CSP concentrations were mainly associated with chlorophyll a (Chl a ) concentration except for the turbid mixing zone, suggesting that autochthonous phytoplankton production served as the primary source of CSP in the PRE. The concentrations of nitrogen (N) as CSP in the PRE were comparable to the nitrogen content of particulate hydrolysable amino acids (PHAA). Pictures of CSP taken by microscopy and the correlation between composition of PHAA and the ratio of Chl a /CSP color showed that CSP were relatively degraded due to delivery of old terrestrial protein to river section and extensive microbial degradation during mixing at the upper and middle parts of the estuary, whereas CSP in lower estuary appeared to be more labile due to higher fresh algal production. The contribution of CSP nitrogen (CSP-N) to the particulate nitrogen (PN) pool was 34.98% in summer and 30.8% in winter. The conservative estimate of CSP-N input flux in the Pearl River Delta was about 6 × 10 6 mol N d –1 . These results suggested that CSP was a significant pool of organic nitrogen in the PRE. The study of CSP composition in terms of nitrogen provides new insight into the roles of CSP on nitrogen biogeochemical processes in the turbid and productive estuarine system.

Predicting the Drug–Drug Interaction Mediated by CYP3A4 Inhibition: Method Development and Performance Evaluation - Hong-can Ren; Yang Sai; Tao Chen; Chun Zhang; Lily Tang; Cheng-guang Yang (The AAPS Journal, 2022)

New monoterpenoids from the stigmas of Crocus sativus - Qing-Wei Fang; Wen-Wei Fu; Jin-Ling Yang; Yue Lu; Jiang-Cheng Chen; Pei-Ying Wu; Xue Zhang; Hong-Xi Xu (Journal of Natural Medicines, 2022)

YAP regulates porcine skin-derived stem cells self-renewal partly by repressing Wnt/β-catenin signaling pathway - Hong-Chen Yan; Yu Sun; Ming-Yu Zhang; Shu-Er Zhang; Jia-Dong Sun; Paul W. Dyce; Francesca Gioia Klinger; Massimo De Felici; Wei Shen; Shun-Feng Cheng (Histochemistry and Cell Biology, 2022)

Temporal trends of the association between temperature variation and hospitalizations for schizophrenia in Hefei, China from 2005 to 2019: a time-varying distribution lag nonlinear model - Rubing Pan; Zhenhai Yao; Weizhuo Yi; Qiannan Wei; Yangyang He; Chao Tang; Xiangguo Liu; Shasha Son; Yanhu Ji; Jian Song; Jian Cheng; Yifu Ji; et al. (Environmental Science and Pollution Research, 2022)

The combined toxicity and mechanism of multi-walled carbon nanotubes and nano zinc oxide toward the cabbage - Mo Hong; Ji-Lai Gong; Wei-Cheng Cao; Rong Fang; Zhe Cai; Jun Ye; Zeng-Ping Chen; Wang-Wang Tang (Environmental Science and Pollution Research, 2022)

Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells - Xiang-xing Zhu; Jia-sheng Pan; Tao Lin; Ye-cheng Yang; Qiu-yan Huang; Shuai-peng Yang; Zi-xiao Qu; Zi-sheng Lin; Jian-cong Wen; Ai-fen Yan; Juan Feng; Lian Liu; et al. (Biotechnology Letters, 2022)

Different changes in pre- and postsynaptic components in the hippocampal CA1 subfield after transient global cerebral ischemia - Yan Zhang; Bai-Hong Tan; Shuang Wu; Cheng-Hao Wu; Jia-Le Suo; Yue Gui; Cheng-Mei Zhou; Yan-Chao Li (Brain Structure and Function, 2022)

Isolation and partial characterization of a novel bacteriocin from Pseudomonas azotoformans with antimicrobial activity against Pasterella multocida - Yu Wang; Shuang Lei; Inam Muhammad; Yu Jia; Cheng-guang He; Yi-Ming Wang; Yun-Hang Gao; Ling-Cong Kong; Hong-Xia Ma (Archives of Microbiology, 2022)

Optimization of Spray-Drying Process Parameters to Study Anti-Sticking Effect of Hydroxypropyl Methyl Cellulose-VLV on Corni fructus Extracts - Hong Cheng; Chenghao Lu; Gangfeng Xu; Lijie Zhao; Min Lu; Youjie Wang (AAPS PharmSciTech, 2022)

Cytotoxic benzopyranone and xanthone derivatives from a coral symbiotic fungus Cladosporium halotolerans GXIMD 02502 - Chao-Nan Wang; Hu-Mu Lu; Cheng-Hai Gao; Lang Guo; Zhen-Yu Zhan; Jun-Jian Wang; Yong-Hong Liu; Song-Tao Xiang; Jian Wang; Xiao-Wei Luo (Natural Product Research, 2021)

Fiber-optic wireless sensor network using ultra-weak fiber Bragg gratings for vertical subsurface deformation monitoring - Su-Ping Liu; Bin Shi; Kai Gu; Cheng-Cheng Zhang; Jian-Hui He; Jing-Hong Wu; Guang-Qing Wei (Natural Hazards, 2021)

Genome-wide identification and expression analysis of glycosyltransferase gene family 1 in Quercus robur L. - Jie Zhang; Li-Mei Lin; Wen-Wen Cheng; Xin Song; Yue-Hong Long; Zhao-Bin Xing (Journal of Applied Genetics, 2021)

Effects of different heat exposure patterns (accumulated and transient) and schizophrenia hospitalizations: a time-series analysis on hourly temperature basis - Chao Tang; Yifu Ji; Qingru Li; Zhenhai Yao; Jian Cheng; Yangyang He; Xiangguo Liu; Rubing Pan; Qiannan Wei; Weizhuo Yi; Hong Su (Environmental Science and Pollution Research, 2021)

Evaluation of life expectancy loss associated with submicron and fine particulate matter (PM1 and PM2.5) air pollution in Nanjing, China - Hao Zheng; Weizhuo Yi; Zhen Ding; Zhiwei Xu; Hung Chak Ho; Jian Cheng; Mohammad Zahid Hossain; Jian Song; Yinguang Fan; Jing Ni; Qingqing Wang; Yan Xu; et al. (Environmental Science and Pollution Research, 2021)

Establishment of an immortalized cell line derived from the pupal ovary of Mythimna separata (Lepidoptera: Noctuidae) and identification of the cell source - Yan Tong; Lu-Qiang Cheng; Xuan Li; Xu-Peng Yu; Rui-Hao Shu; Ji-Hong Zhang; Qian Meng; Qi-Lian Qin; Kai Tang; Jian-Xiang Xu; Huan Zhang (Cell and Tissue Research, 2021)

Study on the Pyrolysis Characteristics, Kinetics and Mineral Transformation of Paper Sludge - Yanshan Yin; Huixia Yin; Zihan Yuan; Zihua Wu; Wei Zhang; Hong Tian; Leihua Feng; Shan Cheng; Mengxia Qing; Quanbin Song (BioEnergy Research, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

Alentiana palinpoda, a new commensal polynoid species from a seamount in the Northwest Pacific Ocean - Yueyun Wang; Hong Cheng; Chunsheng Wang (Acta Oceanologica Sinica, 2021)

Ophiuroid fauna of cobalt-rich crust seamounts in the Northwest Pacific Ocean - Wanying Chen; Jieying Na; Chengcheng Shen; Ruiyan Zhang; Bo Lu; Hong Cheng; Chunsheng Wang; Dongsheng Zhang (Acta Oceanologica Sinica, 2021)

A new eyeless species of Nicon (Annelida: Nereididae) from the deep Northwest Pacific Ocean - Yueyun Wang; Hong Cheng; Chunsheng Wang (Acta Oceanologica Sinica, 2021)

A new species of the glass sponge genus Walteria (Hexactinellida: Lyssacinosida: Euplectellidae) from northwestern Pacific seamounts, providing a biogenic microhabitat in the deep sea - Chengcheng Shen; Hong Cheng; Dongsheng Zhang; Bo Lu; Chunsheng Wang (Acta Oceanologica Sinica, 2021)

Monitoring Sediment and Water Chemistry in Small Remote Aquatic Systems in East Sepik Province, Papua New Guinea - Pei Sun Loh; Chen-Tung Arthur Chen; Ting-Hsuan Huang; Hon-Kit Lui; Jiann-Yuh Lou; Hong-Wei Yuan; Long-Xiu Cheng; Xue-Gang Chen; Jianfang Chen (Water, Air, & Soil Pollution, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

Particulate matter pollution associated with schizophrenia hospital re-admissions: a time-series study in a coastal Chinese city - Yanhu Ji; Bin Liu; Jian Song; Rubing Pan; Jian Cheng; Hong Su; Heng Wang (Environmental Science and Pollution Research, 2021)

Differential metabolism-associated gene expression of duck pancreatic cells in response to two strains of duck hepatitis A virus type 1 - Zhen Chen; Shao-hua Shi; Yu Huang; Cui-qin Huang; Rong-chang Liu; Long-fei Cheng; Guang-hua Fu; Hong-mei Chen; Chun-he Wan; Qiu-ling Fu (Archives of Virology, 2021)
Several outbreaks of duck hepatitis A virus type 1 (DHAV-1), which were characterized by yellow coloration and hemorrhage in pancreatic tissues, have occurred in China. The causative agent is called pancreatitis-associated DHAV-1. The mechanisms involved in pancreatitis-associated DHAV-1 infection are still unclear. Transcriptome analysis of duck pancreas infected with classical-type DHAV-1 and pancreatitis-associated DHAV-1 was carried out. Deep sequencing with Illumina-Solexa resulted in a total of 53.9 Gb of clean data from the cDNA library of the pancreas, and a total of 29,597 unigenes with an average length of 993.43 bp were generated by de novo sequence assembly. The expression levels of D-3-phosphoglycerate dehydrogenase, phosphoserine aminotransferase, and phosphoserine phosphatase, which are involved in glycine, serine, and threonine metabolism pathways, were significantly downregulated in ducks infected with pancreatitis-associated DHAV-1 compared with those infected with classical-type DHAV-1. These findings provide information regarding differences in expression levels of metabolism-associated genes between ducks infected with pancreatitis-associated DHAV-1 and those infected with classical-type DHAV-1, indicating that intensive metabolism disorders may contribute to the different phenotypes of DHAV-1-infection.

Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1 - Guang-Tong Jiang; Lin Shao; Shuo Kong; Meng-Liu Zeng; Jing-Jing Cheng; Tao-Xiang Chen; Song Han; Jun Yin; Wan-Hong Liu; Xiao-Hua He; Yu-Min Liu; Lanzi Gongga; et al. (Neuroscience Bulletin, 2021)

MiR-135-5p Alleviates Bone Cancer Pain by Regulating Astrocyte-Mediated Neuroinflammation in Spinal Cord through JAK2/STAT3 Signaling Pathway - Ming Liu; Xuefeng Cheng; Hong Yan; Jingli Chen; Caihua Liu; Zhonghui Chen (Molecular Neurobiology, 2021)

Overexpression of HOTAIR attenuates Pi-induced vascular calcification by inhibiting Wnt/β-catenin through regulating miR-126/Klotho/SIRT1 axis - Yan Chen; Chong Huang; Shu-Ying Zhu; Hong-Chang Zou; Cheng-Yun Xu; Yan-Xia Chen (Molecular and Cellular Biochemistry, 2021)

Aquamicrobium zhengzhouense sp. nov., a Bacterium Isolated from Farmland Soil Applied with Amino Acid Fertilizer - Xiang Wang; Chun-Fu Zhou; Jia-Rong Cheng; Sheng-Fei Cao; Hong-Xing Yang; Jian-Rong Zhao (Current Microbiology, 2021)

An efficient genetic manipulation protocol for dark septate endophyte Falciphora oryzae - Zhen-Zhu Su; Meng-Di Dai; Jia-Nan Zhu; Yu-Lan Zeng; Xuan-Jun Lu; Xiao-Hong Liu; Fu-Cheng Lin (Biotechnology Letters, 2021)

LncRNA MALAT1 Functions as a Competing Endogenous RNA to Regulate BMI1 Expression by Sponging miR-200c/miR-203 in the Control of the Differentiation of Pulp Cells - Hong Jin; Junhai Zhao; Cheng Li (Biochemical Genetics, 2021)

Optimizing staggered-grid finite-difference method based on the least-squares combination of the square window function - Chao-pu Chen; Hong Liu; Zhi-yang Wang; Wen-lei Bai; Cheng-fang Zhang; Zi-rui Meng (Applied Geophysics, 2021)

Modulation of the 5-HT 3 A receptor current by desacylbaldrinal - Li-Xia Wang; Hu-Lan Chen; Hong-Ling Yan; Fei Tang; Hai Zhang; Hong-Xiang Li; Qiang Ye; Cheng Peng; Yu-Zhu Tan (Natural Product Research, 2021)

Molecular cloning and sequence analysis of a mitogen-activated protein kinase gene in the Antarctic yeast Rhodotorula mucilaginosa AN5 - Cuijuan Shi; Hong Zhang; Kai Yu; Yingying Wang; Jie Jiang; Yun Ju; Chuanzhou Zhang; Ziyi Cheng; Guangfeng Kan (Molecular Biology Reports, 2021)

Remelting of a Neoproterozoic arc root: origin of the Pulang and Songnuo porphyry Cu deposits, Southwest China - Dian-Zhong Wang; Ruizhong Hu; Pete Hollings; Xian-Wu Bi; Hong Zhong; Li-Chuan Pan; Cheng-Biao Leng; Ming-Liang Huang; Jing-Jing Zhu (Mineralium Deposita, 2021)

Active components from Lagotis brachystachya maintain uric acid homeostasis by inhibiting renal TLR4-NLRP3 signaling in hyperuricemic mice - Ji-Xiao Zhu; Hai-Yan Yang; Wei-Qiong Hu; Jie Cheng; Yang Liu; Li-Tao Yi; Hong-Yu Cheng (Inflammopharmacology, 2021)

Maternal exposure to sulfur dioxide and the risk of oral clefts in Liaoning Province, China: a population-based case-control study - Fang-Hua Liu; Ze Xing; Ting-Ting Gong; Jia-Yu Zhang; Yan-Hong Huang; Jing Li; Shu Liu; Yan-Ling Chen; Li-Li Li; Cheng-Zhi Jiang; Zong-Jiao Chen; Yu-Hong Zhao; et al. (Environmental Science and Pollution Research, 2021)

The correlation of altitude with gingival status among adolescents in western China: a cross-sectional study - Zhiwu Wu; Rui Zhang; Li Cheng; Ruilie Cai; Hong Chen; Ran Cheng; Tao Hu (Environmental Geochemistry and Health, 2021)

Sorghum breeding in the genomic era: opportunities and challenges - Huaiqing Hao; Zhigang Li; Chuanyuan Leng; Cheng Lu; Hong Luo; Yuanming Liu; Xiaoyuan Wu; Zhiquan Liu; Li Shang; Hai-Chun Jing (Theoretical and Applied Genetics, 2021)

Transcriptome analysis of differentially expressed genes in chrysanthemum MET1 RNA interference lines - Dong-ru Kang; Yi Zhu; Shuai-lei Li; Peng-hui Ai; Muhammad Ayoub Khan; Hong-xu Ding; Ying Wang; Zi-cheng Wang (Physiology and Molecular Biology of Plants, 2021)

Molecular characterization of a novel fusarivirus infecting the plant-pathogenic fungus Alternaria solani - WeiJie Gong; Hong Liu; XiaoFei Zhu; ShiYun Zhao; JiaLe Cheng; Hongjian Zhu; Jie Zhong; Qian Zhou (Archives of Virology, 2021)

Foetidibacter luteolus gen. nov., sp. nov., isolated from the rhizosphere of Salvia miltiorrhiza - Qian Pu; Guo-hong Zeng; Gui-wei Wang; Ling-er Lu; Ang Li; Xu-rui Cheng; Xue-ying Wang; Ou Li; Cong Sun; Xiu-fang Hu (Archives of Microbiology, 2021)

Helios serves as a suppression marker to reduce regulatory T cell function in pancreatic cancer patients - Min-Feng Liu; Cheng Jin; Tao Wu; En-Hong Chen; Minxue Lu; Huan-Long Qin (Immunologic Research, 2021)

Proton Pump Inhibitor Exposure and Acute Myocardial Infarction Risk: A Nested Cohort Study - Hsiang-Jung Tseng; Chih-Ming Cheng; Shih-Jen Tsai; Wei-Chen Lin; Ya-Mei Bai; Chia-Fen Tsai; Tung-Ping Su; Cheng-Ta Li; Tzeng-Ji Chen; Mu-Hong Chen (Cardiovascular Toxicology, 2021)

Molecular characterization of a novel single-stranded RNA virus, ChRV1, isolated from the plant-pathogenic fungus Colletotrichum higginsianum - Hong Liu; Hui Wang; Xun Lu; Cheng Xiao; Bo Peng; Qian Zhou (Archives of Virology, 2021)

Ground roll separation method via threshold filtering and constraint of seismic wavelet support in curvelet domain - De-ying Wang; Li-hua Chen; Lie-qian Dong; Li-hong Zhao; Ren-wei Ding; Cheng-zhen Ding (Applied Geophysics, 2021)

Reduction of OsMPK6 activity by a R89K mutation induces cell death and bacterial blight resistance in rice - Dongfei Wang; Hong Wang; Qunen Liu; Ranran Tu; Xingpeng Zhou; Yingxin Zhang; Weixun Wu; Ping Yu; Daibo Chen; Xiaodeng Zhan; Liyong Cao; Shihua Cheng; et al. (Plant Cell Reports, 2021)

On the ~ 7 year periodic signal in length of day from a frequency domain stepwise regression method - Can-Can Hsu; Peng-Shuo Duan; Xue-Qing Xu; Yong-Hong Zhou; Cheng-Li Huang (Journal of Geodesy, 2021)
The intradecadal variations in length-of-day (LOD) and their time-varying characteristics still need to be further studied. Given that the corresponding signal periods on the intradecadal scales are quite close to each other and the span of currently observed ΔLOD data (i.e., 1962–2019, only 57 years) is not long enough, accurate detection of these signals depends on using effective mathematical method. On the basis of the traditional harmonic retrieval model, this work proposes a frequency domain stepwise regression method, which can well identify the periodic components with close periods and recognize the weaker signals to estimate the relevant harmonic parameters (i.e., amplitude, frequency and phase). Furthermore, we apply this method to detection of the actual LOD intradecadal variations, the result of which shows that there are three components (i.e., the ~ 5.9 years, ~ 8.3 years and ~ 7.3 years) existing in LOD intradecadal variations. Here, we firstly give the time-domain harmonic expression of the ~ 7.3 years signal, i.e., $$y\left(t\right)=Acos\left(\frac{2π }{T}\left(t-1962+ψ \right)\right)$$ y t = A cos 2 π T t - 1962 + ψ , where the period $$T=7.33$$ T = 7.33 years, amplitude $$A=0.0413(± 0.0099)$$ A = 0.0413 ( ± 0.0099 ) ms, phase $$ψ =-1.58(± 0.30)$$ ψ = - 1.58 ( ± 0.30 ) years. The mechanism of this ~ 7.3 years signal needs to be further studied.

Genome-wide identification and expression analysis of the MADS-box transcription factor family in Camellia sinensis - Zai-Bao Zhang; Yuan-Jin Jin; Hou-Hong Wan; Lin Cheng; Zhi-Guo Feng (Journal of Applied Genetics, 2021)

Bi-allelic BRWD1 variants cause male infertility with asthenoteratozoospermia and likely primary ciliary dyskinesia - Ting Guo; Chao-Feng Tu; Dan-Hui Yang; Shui-Zi Ding; Cheng Lei; Rong-Chun Wang; Lv Liu; Xi Kang; Xiao-Qing Shen; Yi-Feng Yang; Zhi-Ping Tan; Yue-Qiu Tan; et al. (Human Genetics, 2021)

Influence of major water conservation projects on river channels and shorelines in the middle and lower reaches of the Yangtze River - Yue-hua Jiang; He-qin Cheng; Quan-ping Zhou; Yun Li; Guo-qiang Yang; Yang Jin; Shi-jia Mei; Xuan Gu; Hong Zhang (Arabian Journal of Geosciences, 2021)

A phenological object-based approach for rice crop classification using time-series Sentinel-1 Synthetic Aperture Radar (SAR) data in Taiwan - Nguyen-Thanh Son; Chi-Farn Chen; Cheng-Ru Chen; Piero Toscano; Youg-Sing Cheng; Hong-Yuh Guo; Chien-Hui Syu (International Journal of Remote Sensing, 2021)

Phylogeny and taxonomy of two new Alternaria (Ascomycota: Pleosporaceae) species in section Gypsophilae from China - Lin He; Hong Cheng; Aye Aye Htun; Hui Ge; Zhen Zhou Xia; Jian Wei Guo; Jian Xin Deng; Tao Du (Mycological Progress, 2021)

Late Cretaceous granitic magmatism and Sn mineralization in the giant Yinyan porphyry tin deposit, South China: constraints from zircon and cassiterite U–Pb and molybdenite Re–Os geochronology - Peng-Cheng Hu; Wei-Guang Zhu; Hong Zhong; Rong-Qing Zhang; Xiao-Yu Zhao; Wei Mao (Mineralium Deposita, 2021)

COVID-19 illness and autoimmune diseases: recent insights - Juan Li; Hong-Hui Liu; Xiao-Dong Yin; Cheng-Cheng Li; Jing Wang (Inflammation Research, 2021)

Anti-inflammatory monoterpene esters from the stems of Illigera aromatica - Xiao-Yun Pu; Kai Tian; Jing-Xian Sun; Wei Wang; Hong-Cheng Liu; Juan Yang; Meng-Yuan Jiang; Xiang-Zhong Huang (Natural Product Research, 2021)

Sesquiterpenoids from the roots and rhizomes of Valeriana amurensis and their effects on NGF-induced neurite outgrowth in PC12 cells - Fa-Wu Dong; Fang Li; Jia-Jia Ren; Cheng-Mei Zhao; Hong-Li Diao; Bao-Jing Li; Yan-Ping Li; Jiang-Miao Hu; Hong-Ping He (Natural Product Research, 2021)

Interest-activity symptom severity predicts response to ketamine infusion in treatment-resistant depression - Mu-Hong Chen; Wei-Chen Lin; Hui-Ju Wu; Ya-Mei Bai; Cheng-Ta Li; Shih-Jen Tsai; Chen-Jee Hong; Pei-Chi Tu; Tung-Ping Su (Psychopharmacology, 2021)

Maternal exposure to ambient SO2 and risk of polydactyly and syndactyly: a population-based case-control study in Liaoning Province, China - Yu-Ting Jiang; Ting-Ting Gong; Jia-Yu Zhang; Yan-Hong Huang; Jing Li; Shu Liu; Yan-Ling Chen; Li-Li Li; Cheng-Zhi Jiang; Zong-Jiao Chen; Yu-Hong Zhao; Qi-Jun Wu (Environmental Science and Pollution Research, 2021)

Diversity-oriented synthesis and antifungal activities of novel pimprinine derivative bearing a 1,3,4-oxadiazole-5-thioether moiety - Zi-Long Song; Yun Zhu; Jing-Rui Liu; Shu-Ke Guo; Yu-Cheng Gu; Xinya Han; Hong-Qiang Dong; Qi Sun; Wei-Hua Zhang; Ming-Zhi Zhang (Molecular Diversity, 2021)

High-sulfidation veins in the Jiama porphyry system, South Tibet - Shi-Ji Zheng; Hong Zhong; Zhong-Jie Bai; Zhong-Kun Zhang; Cheng-Quan Wu (Mineralium Deposita, 2021)

δ-Opioid receptor activation ameliorates lipopolysaccharide-induced inflammation and apoptosis by inhibiting the MAPK/caspase-3 pathway in BV2 microglial cells - Min Cheng; Yue Geng; Yeting Chen; Yongjie Zhang; Runjie Guo; Hong Xu; Jianfeng Liang; Jiajun Xie; Zean Zhang; Xuesong Tian (Experimental Brain Research, 2021)

Effects of lithium resource exploitation on surface water at Jiajika mine, China - Juan-Qin Gao; Yang Yu; Deng-Hong Wang; Wei Wang; Cheng-Hui Wang; Hong-Zhang Dai; Xue-Feng Hao; Kuang Cen (Environmental Monitoring and Assessment, 2021)

A case study on deformation characteristics of a large cross-section tunnel passing through a soft-plastic layer with different spatial locations - Qiuyang Hong; Hongpeng Lai; Yuyang Liu; Rui Chen; Cheng Liu; Juntai Xie (Arabian Journal of Geosciences, 2021)

Insights into the aridification history of Central Asian Mountains and international conservation strategy from the endangered wild apple tree - Hong‐Xiang Zhang; Xiao‐Shuang Li; Jian‐Cheng Wang; Dao‐Yuan Zhang (Journal of Biogeography, 2021)
Aim Evolutionary processes of mountain plants in arid lands remain poorly understood. Here, we investigate population genomics of the endangered wild apple tree to interpret the effects of long‐term aridification on plant diversification and demographical history in Central Asian Mountains. Location The Tianshan Mountains, spanning north‐western China, Kazakhstan, Kyrgyzstan and Tajikistan. Taxon Malus sieversii (Rosaceae) Methods Using genome‐wide single nucleotide polymorphisms, we assessed genetic diversity and genetic structure of 15 populations across the species' range. Demographical history was simulated with approximate Bayesian computation and species distribution modelling. We used a general linear model to identify key environmental factors affecting population genetic diversity and structure. Results We separated the 15 populations into three groups: the eastern group of western Junggar Mountains in China; the central group of the Ili Valley, the Talas Alatau Mountains in Kazakhstan and Kyrgyzstan; and the western group of Tajikistan and the Dzungarian Alatau in Kazakhstan. Central populations had higher genetic diversity and effective population size than eastern and western populations. The three groups split at the late Miocene and subsequently experienced extensive admixture. We detected a significant pattern of isolation by distance, but not isolation by environment, among these populations. Population genetic diversity was significantly associated with longitudinal and current environmental gradients. Main conclusions Long‐term aridification promoted distribution fragmentation and plant lineage divergence of relict broad‐leaved forests in Central Asian Mountains. Both geographical isolation and environmental heterogeneity shaped spatial patterns in genetic variation among M. sieversii populations. To maintain genetic integrity, we propose the establishment of an international network for the conservation of this endangered wild apple tree.

PapA , a peptidoglycan‐associated protein, interacts with OmpC and maintains cell envelope integrity - Yun‐Hao Wang; Hong‐He Chen; Zhou Huang; Xiao‐Jing Li; Nan Zhou; Chang Liu; Cheng‐Ying Jiang; De‐Feng Li; Shuang‐Jiang Liu (Environmental Microbiology, 2021)
Summary The bacterial cell envelope is critical to support and maintain cellular life. In Gram‐negative bacterial cells, the outer membrane and the peptidoglycan layer are two important parts of the cell envelope and they harbour abundant proteins. Here, we report the identification and characterization of a previously unknown p eptidoglycan‐ a ssociated p rotein, PapA, from the Gram‐negative Comamonas testosteroni . PapA bound peptidoglycan with its C‐terminal domain and interacted with the outer‐membrane porin OmpC. The PapA‐OmpC complex riveted the outer membrane and the peptidoglycan layer, and played a role in maintaining cell envelope integrity. When papA was disrupted, the mutant CNB‐1Δ papA apparently had an outer membrane partly separated from the peptidoglycan layer. Phenotypically, the mutant CNB‐1Δ papA lost chemotactic responses and had longer lag‐phase of growth, less flagellation and higher sensitivity to harsh environments. Totally, 1093 functionally unknown PapA homologues were identified from the public NR protein database and they were mainly distributed in Burkholderiales of Betaproteobacteria. Our finding provides a clue that the PapA homologous proteins might function as a rivet to maintain cell envelope integrity in those Gram‐negative bacteria.

Sesquiterpenoids and meroterpenoids from a mangrove derived fungus Diaporthe sp. SCSIO 41011 - Xiao-Wei Luo; Chun-Mei Chen; Kun-Long Li; Xiu-Ping Lin; Cheng-Hai Gao; Xue-Feng Zhou; Yong-Hong Liu (Natural Product Research, 2021)

Water and energy circulation characteristics and their impacts on water stress at the provincial level in China - Siyang Hong; Hong Yang; Hongrui Wang; Tao Cheng (Stochastic Environmental Research and Risk Assessment, 2021)

Dual Mechanism of a New SMN1 Variant (c.835G>C, p.Gly279Arg) by Interrupting Exon 7 Skipping and YG Oligomerization in Causation of Spinal Muscular Atrophy - JinLi Bai; YuJin Qu; Fang Song; YanYan Cao; Miaomiao Cheng; Jia Wang; YuWei Jin; Hong Wang (Journal of Molecular Neuroscience, 2021)

A new self-starting drainage method for slope stabilization and its application - Hong-yue Sun; Qi Ge; Yang Yu; Fei-xiang Shuai; Cheng-cheng Lü (Bulletin of Engineering Geology and the Environment, 2021)

Phytochemical and antitumor studies on Cynanchum mongolicum (Maxim.) Kom - Yong-Cheng Yang; Yan-Ming Wang; Zi-Jian Rong; Li-Na Hong; Qian Zhang; Jing-Ming Jia; An-Hua Wang (Natural Product Research, 2020)

Two new lignans from Zanthoxylum armatum - Yan Sun; Qing-Hong Zeng; Hui-Qiang Lu; Fan-Cheng Meng; Yong Shen; Wei-You Zeng; Hao Chi; Yu-Qiang Zhou; Min Chen (Natural Product Research, 2020)

A Clipless Pedal-Sensor System for Three Dimensional Kinetic Analysis During Cycling - Kai-Han Liang; Hong-Wen Wu; Li-Cheng Hsieh; Yi-Wen Chang (Journal of Medical and Biological Engineering, 2020)

Geographical origin differentiation of Chinese Angelica by specific metal element fingerprinting and risk assessment - Lei Sun; Xiao Ma; Hong-Yu Jin; Chang-jun Fan; Xiao-dong Li; Tian-Tian Zuo; Shuang-Cheng Ma; Sicen Wang (Environmental Science and Pollution Research, 2020)

One-pot synthesis of substituted pyrrole–imidazole derivatives with anticancer activity - Ming Zhang; Yong Ding; Hong-Xia Qin; Zhi-Gang Xu; Hai-Tao Lan; Dong-Lin Yang; Cheng Yi (Molecular Diversity, 2020)

Characterization of a Protease Hyper-Productive Mutant of Bacillus pumilus by Comparative Genomic and Transcriptomic Analysis - Yong-Cheng Liu; Lin-Li Han; Tian-Yu Chen; Yan-Bing Lu; Hong Feng (Current Microbiology, 2020)

Prevalence of Clonorchis sinensis infection in fish in South‐East Asia: A systematic review and meta‐analysis - Ying Zhang; Qing‐Long Gong; Qing‐Bo Lv; Yang‐Yuan Qiu; Yan‐Chun Wang; Hong‐Yu Qiu; Xin‐Rui Guo; Jun‐Feng Gao; Qiao‐Cheng Chang; Chun‐Ren Wang (Journal of Fish Diseases, 2020)
Clonorchis sinensis , an important fish‐borne zoonotic trematode, is widely distributed in South‐East Asia, especially in China. Infections from human and animal reservoir hosts occur due to the consumption of raw or undercooked fish with C. sinensis metacercariae. This study aimed to evaluate the prevalence of C. sinensis metacercariae in fish in South‐East Asia via systematic review and meta‐analysis. We searched PubMed, ScienceDirect, China National Knowledge Infrastructure, Wanfang and Chongqing VIP databases for studies published between 1976 and 2020 that are related to the prevalence of C. sinensis metacercariae in fish. Studies were screened with keywords based on inclusion and exclusion criteria. Seventy‐one eligible articles were identified, covering three countries: China, Korea and Vietnam. The pooled prevalence of C. sinensis metacercariae in fish from South‐East Asia was 30.5%, with 35.1% in China, 29.7% in Korea and 8.4% in Vietnam. In subgroup analyses of climate, season, water source and publication date, the highest prevalence was identified in the Dwb climate type (43.3%), summer (70.2%), river (34.5%) and pre‐2001 publications (38.9%), respectively. In comparison, the lowest prevalence was found in the Dfa climate type (14.5%), winter (19.5%), lake (8.0%) and post‐2001 publications (23.8%). Meta‐regression results indicated that country ( p = .009), the published time ( p = .035) and water source subgroups ( p = .003) may be the source of heterogeneity. Overall, our study indicates that a high prevalence of C. sinensis infections occurs in fish in China, Korea and Vietnam, illuminating a significant public health concern in these countries.

Complex magma sources of late Mesozoic granites along the southern margin of the North China Craton: constraints from geochemistry and geochronology of the massive Heyu and Lantian plutons - Yan Wang; Yuan-Shuo Zhang; Hong Cheng; Fukun Chen (International Geology Review, 2020)

Evaluation of the Parasitism Capacity of Egg Parasitoid Telenomus dignus on Chilo sacchariphagus - Xue-Hong Pan; Ji-Li Wei; Xian-Kun Shang; Cheng-Hua Huang; Amin Nikpay; François-Régis Goebel (Sugar Tech, 2020)

Liquiritin inhibits proliferation and induces apoptosis in HepG2 hepatocellular carcinoma cells via the ROS-mediated MAPK/AKT/NF-κB signaling pathway - Jia-Ru Wang; Tian-Zhu Li; Cheng Wang; Shu-Mei Li; Ying-Hua Luo; Xian-Ji Piao; Yu-Chao Feng; Yi Zhang; Wan-Ting Xu; Yu Zhang; Tong Zhang; Shi-Nong Wang; et al. (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Spatial and seasonal variations and risk assessment for heavy metals in surface sediments of the largest river-embedded reservoir in China - Peng Yuan; Xuefei Wu; Yuqi Xia; Cheng Peng; Hong Tong; Jianshe Liu; Lei Jiang; Xianyun Wang (Environmental Science and Pollution Research, 2020)

Characteristics of the spike and ORF3 genes of porcine epidemic diarrhea virus in Henan and Shanxi provinces of China - Jian-tao Cui; Han Qiao; Cheng-yao Hou; Hui-Hua Zheng; Xin-Sheng Li; Lan-lan Zheng; Hong-Ying Chen (Archives of Virology, 2020)

Archaeobotanical evidence reveals the human–environment interactions during the 9th–13th centuries at Turpan, Xinjiang on the ancient Silk Road - Yi-Feng Yao; Xia Wang; Wu Guo; Hong-En Jiang; Min Li; David K. Ferguson; Yu-Fei Wang; Cheng-Sen Li (Vegetation History and Archaeobotany, 2020)

Silencing of long non-coding RNA CRNDE promotes autophagy and alleviates neonatal hypoxic-ischemic brain damage in rats - Chun-Hua Fu; Fang-Fang Lai; Sai Chen; Cai-Xia Yan; Bing-Hong Zhang; Cheng-Zhi Fang; Gao-Hua Wang (Molecular and Cellular Biochemistry, 2020)

Lacustrine record from the eastern Tibetan Plateau associated with Asian summer monsoon changes over the past ~ 6 ka and its links with solar and ENSO activity - Guodong Ming; Weijian Zhou; Peng Cheng; Hong Wang; Feng Xian; Yunchong Fu; Shugang Wu; Hua Du (Climate Dynamics, 2020)

Key Role of Pro-inflammatory Cytokines in the Toxic Effect of Fluoride on Hepa1-6 Cells - Yan Zhang; Bian-hua Zhou; Pan-pan Tan; Yu Chen; Cheng-yi Miao; Hong-wei Wang (Biological Trace Element Research, 2020)

Mixture of Pb, Zn and Cu on root permeability and radial oxygen loss in the mangrove Bruguiera gymnorrhiza - Hao Cheng; You-Shao Wang; Chang-Da Li; Zhi-Hong Ye; Shafi Muhammad; Mei-Lin Wu; Fun-Lin Sun (Ecotoxicology, 2020)

Correlation Between CCG Polymorphisms and CAG Repeats During Germline Transmission in Chinese Patients with Huntington’s Disease - Hong-Rong Cheng; Xiao-Yan Li; Hui-Li Yu; Miao Xu; Yan-Bin Zhang; Shi-Rui Gan; Hong-Lei Li; Zhi-Ying Wu (Neuroscience Bulletin, 2020)

Population Genetic Analysis for Stock Enhancement of Silver Sea Bream (Rhabdosargus sarba) in Taiwan - Te-Hua Hsu; Chang-Wen Huang; Hung-Tai Lee; Yi-Hsuan Kuo; Kwang-Ming Liu; Cheng-Hui Lin; Hong-Yi Gong (Fishes, 2020)
Stock enhancement is a method for replenishing depleted wild finfish populations by supplementing them with hatchery-raised fish. In Taiwan, silver sea bream (Rhabdosargus sarba) is a predominant commercial species involved in stock enhancement projects. Although management agencies conduct stock enhancement projects, there are a lot of private releases without records. Stock enhancement is performed by the private aquaculture sector without accurate genetic records, potentially leading to unintended consequences for wild populations. We analyzed the genetics of 459 wild and 701 hatchery-reared specimens from nine batches produced by various hatcheries. Wild and hatchery-reared samples could be considered two separate clades by using a set of stable and informative microsatellite markers including type I (from gene introns and 3′UTR) and type II markers (randomly picked up from genome). Type I microsatellite markers could more sensitively reflect the loss of genetic diversity more than type II markers in the domestication process. All specimens were considered native by using mtDNA COI and microsatellites. The genetic composition of the wild population is relatively simple, and the estimated low contribution rate of the hatchery stock (1.3–10.9%; 6–50/459) indicated a weak but significant genetic effect of stock enhancement. Therefore, establishing standards for the stock enhancement of silver sea bream for more effective supplementation of wild populations is imperative.

Long interpregnancy interval and adverse perinatal outcomes: A retrospective cohort study - Jing Lin; Han Liu; Dan-Dan Wu; Hong-Tao Hu; Hui-Hui Wang; Cheng-Liang Zhou; Xin-Mei Liu; Xiao-Jun Chen; Jian-Zhong Sheng; He-Feng Huang (Science China Life Sciences, 2020)

Cognitive Load of Exercise Influences Cognition and Neuroplasticity of Healthy Elderly: An Exploratory Investigation - Yi-Ping Chao; Changwei W. Wu; Li-Jung Lin; Cheng-Hung Lai; Hong-Yi Wu; Ai-Ling Hsu; Chiao-Nan Chen (Journal of Medical and Biological Engineering, 2020)
This study explored the effects of exercise with either high cognitive load or low cognitive load on cognitive performance and neuroplasticity in healthy elderly. Twenty-eight sedentary community-dwelling seniors participated in this study. Participants were assigned to one of three groups: the control group (C), low-cognitive load exercise group (LE), or high-cognitive load exercise group (HE). Individuals in both exercise groups engaged in moderate-intensity aerobic exercise for 4 months. Resting-state functional MRI and diffusion MRI were used to investigate the effects of intervention on functional and structural connectivity, respectively. Analysis of covariance with baseline, age and the education year as covariates was used to determine the effects of intervention. We found 4 months of exercise with high-cognitive load, but not exercise with low-cognitive load, improved the overall cognitive function of healthy elderly. Additionally, the HE group showed increased resting-state functional connectivity of superior frontal gyrus and anterior cingulate cortex and decreased functional connectivity of middle occipital gyrus and postcentral gyrus. The age-related alterations in local efficiency and betweenness were protected by exercise. Our findings might suggest that exercise with greater cognitive load likely results in greater training effects on cognition and brain connectivity than exercise requiring lower cognitive loads for healthy elderly.

Genetic diversity of Prorocentrum donghaiense population during bloom in the East China Sea revealed by microsatellite - Hong-jia Huang; Chu-qiao Gan; Shao-wen Xiao; Cheng Zou; Srinivasan Balamurugan; Hong-ye Li; Jie-sheng Liu; Wei-dong Yang (Journal of Applied Phycology, 2020)

Association of tiotropium use and the risk of adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials - Mingjin Yang; Yan Zhang; Hong Cheng; Zhibo Xu; Jianqing He (European Journal of Clinical Pharmacology, 2020)

Innovative health risk assessments of heavy metals based on bioaccessibility due to the consumption of traditional animal medicines - Tian-Tian Zuo; Hao-Ran Qu; Hong-Yu Jin; Lei Zhang; Fei-Ya Luo; Kun-Zi Yu; Fei Gao; Qi Wang; Lei Sun; Huai-Zhen He; Shuang-Cheng Ma (Environmental Science and Pollution Research, 2020)

Short-term associations between ambient fine particulate matter pollution and hospital visits for chronic obstructive pulmonary disease in Yinzhou District, China - Cheng-yi Lin; Die Li; Jie-ming Lu; Zhe-bin Yu; Yao Zhu; Peng Shen; Meng-ling Tang; Ming-juan Jin; Hong-bo Lin; Li-ming Shui; Kun Chen; Jian-bing Wang (Environmental Science and Pollution Research, 2020)

The association between prenatal endocrine-disrupting chemical exposure and altered resting-state brain fMRI in teenagers - Jun-Cheng Weng; Chi Ieong Hong; Jeng-Dau Tasi; Chao-Yu Shen; Pen-Hua Su; Shu-Li Wang (Brain Structure and Function, 2020)

Improved production of GTKO/hCD55/hCD59 triple-gene-modified Diannan miniature pigs for xenotransplantation by recloning - Heng Zhao; Yuying Li; Thanapa Wiriyahdamrong; Zaimei Yuan; Yubo Qing; Honghui Li; Kaixiang Xu; Jianxiong Guo; Baoyu Jia; Xuezeng Zhang; Wenmin Cheng; Yanhua Su; et al. (Transgenic Research, 2020)

Molecular Survey and Genetic Diversity of Babesia spp. and Theileria spp. in Cattle in Gansu Province, China - Ming Sun; Guiquan Guan; Zhijie Liu; Jinming Wang; Duoquan Wang; Shufang Wang; Chao Ma; Shengzhong Cheng; Hong Yin; Jianxun Luo (Acta Parasitologica, 2020)

High-frequency direct shoot organogenesis from garlic (Allium sativum L.) inflorescence and clonal fidelity assessment in regenerants - Yan-Bin Wen; Xiao-Xue Liu; Hong-Jiu Liu; Cui-Nan Wu; Huan-Wen Meng; Zhi-Hui Cheng (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Complete mitogenomic and phylogenetic characteristics of the speckled wood-pigeon (Columba hodgsonii) - Hong-Yi Liu; Cheng-He Sun; Ying Zhu; Qing-Zheng Zhang (Molecular Biology Reports, 2020)

Mechanisms behind soil N dynamics following cover restoration in degraded land in subtropical China - Xiangzhou Zheng; Cheng Lin; Baoling Guo; Juhua Yu; Hong Ding; Shaoyun Peng; Jinbo Zhang; Eric Ireland; Deli Chen; Christoph Müller; Yushu Zhang (Journal of Soils and Sediments, 2020)

Performance of water transfer in response to water environment issues in Wuxi, China - Hong Zhou; Jun Liu; Pei Hua; Liang Dong; Cheng Gao; Guoxi Hong; Weidong Li; Haowen Xie; Yawen Wu (Environmental Science and Pollution Research, 2020)

Engineering of glycerol utilization in Pseudomonas chlororaphis GP72 for enhancing phenazine-1-carboxylic acid production - Chen Song; Sheng-Jie Yue; Wen-Hui Liu; Yi-Fan Zheng; Cheng-Hao Zhang; Tong-Tong Feng; Hong-Bo Hu; Wei Wang; Xue-Hong Zhang (World Journal of Microbiology and Biotechnology, 2020)

Effects of Dietary Supplementation of Recombinant Plectasin on Growth Performance, Intestinal Health and Innate Immunity Response in Broilers - Jing Lin Ma; Li Hua Zhao; Dan Dan Sun; Jing Zhang; Yong Peng Guo; Zhi Qiang Zhang; Qiu Gang Ma; Cheng Ji; Li Hong Zhao (Probiotics and Antimicrobial Proteins, 2020)

Dopamine D2 Receptor-Mediated Modulation of Rat Retinal Ganglion Cell Excitability - Ning Yin; Yu-Long Yang; Shuo Cheng; Hong-Ning Wang; Xin Hu; Yanying Miao; Fang Li; Zhongfeng Wang (Neuroscience Bulletin, 2020)

Novel B-chromosome-specific transcriptionally active sequences are present throughout the maize B chromosome - Zi-Jie Hong; Jun-Xiang Xiao; Shu-Fen Peng; Yao-Pin Lin; Ya-Ming Cheng (Molecular Genetics and Genomics, 2020)

Fluoride-induced rectal barrier damage and microflora disorder in mice - Hong-wei Wang; Cheng-yi Miao; Jing Liu; Yan Zhang; Shi-quan Zhu; Bian-hua Zhou (Environmental Science and Pollution Research, 2020)

Phosphorus-fertilisation has differential effects on leaf growth and photosynthetic capacity of Arachis hypogaea L. - Qingwen Shi; Jiayin Pang; Jean Wan Hong Yong; Chunming Bai; Caio Guilherme Pereira; Qiaobo Song; Di Wu; Qiping Dong; Xin Cheng; Feng Wang; Junlin Zheng; Yifei Liu; et al. (Plant and Soil, 2020)

Differential anthocyanin accumulation in radish taproot: importance of RsMYB1 gene structure - Biao Lai; Yuanyi Cheng; Hong Liu; Qiuxia Wang; Qi Wang; Chunlan Wang; Rui Su; Fabo Chen; Huicong Wang; Lina Du (Plant Cell Reports, 2020)

Two new species of Encyrtidae (Hymenoptera: Chalcidoidea) from China, parasitoid of Antecerococcus roseus (Green) (Hemiptera: Cerococcidae) on Boehmeria nivea (L.) Gaud - Guo-Hao Zu; Ze-Ning Yang; Xin-Sheng Cao; Yuan-Hong Wang; Cheng-De Li (Phytoparasitica, 2020)

Spinal P2X7R contributes to streptozotocin-induced mechanical allodynia in mice - Cheng-ming Ni; He-ping Sun; Xiang Xu; Bing-yu Ling; Hui Jin; Yu-qiu Zhang; Zhi-qi Zhao; Hong Cao; Lan Xu (Journal of Zhejiang University-SCIENCE B, 2020)

CX3CR1 contributes to streptozotocin-induced mechanical allodynia in the mouse spinal cord - Cheng-ming Ni; Bing-yu Ling; Xiang Xu; He-ping Sun; Hui Jin; Yu-qiu Zhang; Hong Cao; Lan Xu (Journal of Zhejiang University-SCIENCE B, 2020)

Investigation of the fecal coliform plumes induced by river discharge and wind stress using a three-dimensional model - Wen-Cheng Liu; Hong-Ming Liu (Environmental Fluid Mechanics, 2020)

Insights into the thermostability and product specificity of a maltooligosaccharide-forming amylase from Bacillus stearothermophilus STB04 - Xiaofang Xie; Xiaofeng Ban; Zhengbiao Gu; Caiming Li; Yan Hong; Li Cheng; Zhaofeng Li (Biotechnology Letters, 2020)

The false smut pathogen Ustilaginoidea virens requires rice stamens for false smut ball formation - Jing Fan; Jie Liu; Zhi‐You Gong; Pei‐Zhou Xu; Xiao‐Hong Hu; Jin‐Long Wu; Guo‐Bang Li; Juan Yang; Yu‐Qiu Wang; Yu‐Feng Zhou; Shuang‐Cheng Li; Li Wang; et al. (Environmental Microbiology, 2020)
Summary Rice false smut has emerged as a serious grain disease in rice production worldwide. The disease is characterized by the transformation of individual rice florets into false smut balls, which is caused by the fungal pathogen Ustilaginoidea virens . To date, little is known about the host factors required for false smut ball formation by U . virens . In this study, we identified histological determinants for the formation of false smut balls by inoculating U . virens into rice floral mutants defective with respect to individual floral parts. The results showed that U . virens could form mature false smut balls in rice floral mutants with defective pistils, but failed to develop false smut balls in the superwoman mutant lacking stamens, identifying that U . virens requires rice stamens to complete its infection cycle. Comparative transcriptome analysis indicated a list of candidate host genes that may facilitate nutrient acquisition by U . virens from the rice stamens, such as SWEET11 , SWEET14 and SUT5 , and genes involved in the biosynthesis of trehalose and raffinose family sugars. These data pinpoint rice stamens as the key target organ of U . virens infection and provide a valuable starting point for dissecting the molecular mechanism of false smut ball formation.

The application of the ‘Gene-deletor’ technology in banana - Chun-hua Hu; Qiao-song Yang; Xiu-hong Shao; Tao Dong; Fang-cheng Bi; Chun-yu Li; Gui-ming Deng; Yi Li; Gan-jun Yi; Tong-xin Dou (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)
Banana ( Musa spp.) is an important tropical crop. Banana industry is under biotic and abiotic stresses such as Fusarium wilt, typhoon, cold stress. Genetic engineering offers a powerful strategy to create germplasm of banana with enhanced resistance. The safety of genetically modified organisms has become a bottleneck restricting the popularization and application of genetically modified technology. In this study, a candidate promoter, LEAFY (LFY) for expression and flower initiation in Arabidopsis , was cloned and constructed to ‘Gene-deletor’ vector. Histochemical β-glucuronidase (GUS) staining results showed that the ‘Gene-deletor’ vector driven by LFY promoter could lead to 88.5% excision efficiency from Arabidopsis seeds based on more than 200 T 3 progeny examined per event. GUS staining was found to be partially negative in transgenic bananas, however, polymerase chain reaction could still detect the presence of large fragments of the vector. These results suggest that although LFY promoter could not completely drive the ‘Gene-deletor’ vector to achieve the effect of complete elimination of exogenous gene in bananas, its efficiency of eliminating exogenous gene laid a theoretical foundation for cloning banana fruit-specific promoters, that is, ‘non-transgenic’ GM bananas.

Transport and distribution of manganese in tidal estuarine system in Taiwan - Wen-Cheng Liu; Poi-Jiu Ken; Hong-Ming Liu (Environmental Science and Pollution Research, 2020)

Association between long-term occupational manganese exposure and bone quality among retired workers - Defu Li; Xiaoting Ge; Zhenfang Liu; Lulu Huang; Yanting Zhou; Peng Liu; Lian Qin; Suzhen Lin; Chaoqun Liu; Qingzhi Hou; Longman Li; Hong Cheng; et al. (Environmental Science and Pollution Research, 2020)

Investigating the contaminant transport of heavy metals in estuarine waters - Wen-Cheng Liu; Hong-Ming Liu; Poi-Jiu Ken (Environmental Monitoring and Assessment, 2020)

Wave and current-induced dynamic response in a multilayered poroelastic seabed - Hui-Feng Qi; Zhang-Long Chen; Yi-Cheng Li; Shi-Jin Feng; Hong-Xin Chen (Bulletin of Engineering Geology and the Environment, 2020)

Expressional and Functional Verification of the Involvement of CmEXPA4 in Chrysanthemum Root Development - Hong Ren; Li-zhu Wen; Yun-hui Guo; Yuan-yuan Yu; Cui-hui Sun; Hong-mei Fan; Fang-fang Ma; Cheng-shu Zheng (Journal of Plant Growth Regulation, 2019)

Tibial growth plate vascularization is inhibited by the dithiocarbamate pesticide thiram in chickens: potential relationship to peripheral platelet counts alteration - Shu-Cheng Huang; Lei Li; Mujeeb Ur Rehman; Jin-dong Gao; Li-hong Zhang; Xiao-le Tong; Muhammad Waqas; Jia-kui Li (Environmental Science and Pollution Research, 2019)

Complete mitochondrial genome sequence for the somali wild ass Equus africanus somaliensis - Hsuan-Yi Hou; Rui-Xuan Chang; Yi-Ning Cheng; Nian-Hong Jang-Liaw (Conservation Genetics Resources, 2019)

Structural characterization and immunosuppressive activity of a new pregnane glycoside from Epigynum cochinchinensis - Yu-Ting Shao; Yan Zhao; Hong Zhang; Meng-Jun Jiang; Afsar Khan; Sheng-Bao Cai; Tian-Rui Zhao; Gui-Guang Cheng; Jian-Xin Cao (Natural Product Research, 2019)

Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice - Sha-Sha Zhang; Yu-Hua Tian; Song-Jun Jin; Wen-Cheng Wang; Jing-Xin Zhao; Xiao-Ming Si; Li Zhang; Hong Xu; Jing-Yu Jin (Psychopharmacology, 2019)

Two new benzophenones from endohydric moss Polytrichum Commune - Xu-Hong Duan; Jian-Cheng Zhao; Lin Li; Lin Pei; Pei He; Rong Wang (Natural Product Research, 2019)

Analytical solutions for the steady-state seepage field in a finite seabed with a lined tunnel - Hong-wei Ying; Cheng-wei Zhu; Xiao-nan Gong; Xiao Wang (Marine Georesources & Geotechnology, 2019)

Reduced Systemic and Brain Exposure with Inhibited Liver Metabolism of Carbamazepine After Its Long-Term Combination Treatment with Piperine for Epilepsy Control in Rats - Tianjing Ren; Min Xiao; Mengbi Yang; Jiajia Zhao; Yufeng Zhang; Mengyun Hu; Yan Cheng; Hong Xu; Chunbo Zhang; Xiaoyu Yan; Zhong Zuo (The AAPS Journal, 2019)

Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B - Fang-Shin Nian; Lei-Li Li; Chih-Ya Cheng; Pei-Chun Wu; You-Tai Lin; Cheng-Yung Tang; Bo-Shiun Ren; Chin-Yin Tai; Ming-Ji Fann; Lung-Sen Kao; Chen-Jee Hong; Jin-Wu Tsai (Molecular Neurobiology, 2019)

Impact of LDB3 gene polymorphisms on clinical presentation and implantable cardioverter defibrillator (ICD) implantation in Chinese patients with idiopathic dilated cardiomyopathy - Dong-fei Wang; Jia-lan Lyu; Juan Fang; Jian Chen; Wan-wan Chen; Jia-qi Huang; Shu-dong Xia; Jian-mei Jin; Fang-hong Dong; Hong-qiang Cheng; Ying-ke Xu; Xiao-gang Guo (Journal of Zhejiang University-SCIENCE B, 2019)

Functional Identification of Apple MdGLK1 Which Regulates Chlorophyll Biosynthesis in Arabidopsis - Xiu-Hong An; Yi Tian; Yan-Hui Chen; En-Mao Li; Min Li; Cun-Gang Cheng (Journal of Plant Growth Regulation, 2019)

Optimized aeration strategies for nitrogen removal efficiency: application of end gas recirculation aeration in the fixed bed biofilm reactor - Jia heng Zhou; Hao cheng Yu; Kai qiang Ye; Hong yu Wang; Yun jie Ruan; Jian ming Yu (Environmental Science and Pollution Research, 2019)

Complete Genome Sequence of Qipengyuania sediminis CGMCC 1.12928T, Shed Light on Its Role in Matter-Cycle and Cold Adaption Mechanism of the Genus Qipengyuania - Yan Gao; Yue-Hong Wu; Lin Xu; Hong Cheng; Chun-Sheng Wang; Xue-Wei Xu (Current Microbiology, 2019)

Experimental Investigation of the Aerodynamic Roughness Length for Flexible Plants - Liqiang Kang; Junjie Zhang; Xueyong Zou; Hong Cheng; Chunlai Zhang; Zhicheng Yang (Boundary-Layer Meteorology, 2019)

Effect of Apolipoprotein E Genotypes on Huntington’s Disease Phenotypes in a Han Chinese Population - Xiao-Yan Li; Yan-Bin Zhang; Miao Xu; Hong-Rong Cheng; Yi Dong; Wang Ni; Hong-Lei Li; Zhi-Ying Wu (Neuroscience Bulletin, 2019)

Impacts of exposure to ambient temperature on burden of disease: a systematic review of epidemiological evidence - Jian Cheng; Zhiwei Xu; Hilary Bambrick; Hong Su; Shilu Tong; Wenbiao Hu (International Journal of Biometeorology, 2019)

F‐box proteins MoFwd1, MoCdc4 and MoFbx15 regulate development and pathogenicity in the rice blast fungus Magnaporthe oryzae - Huan‐Bin Shi; Nan Chen; Xue‐Ming Zhu; Shuang Liang; Lin Li; Jiao‐Yu Wang; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2019)
Summary The Skp1‐Cul1‐F‐box‐protein (SCF) ubiquitin ligases are important parts of the ubiquitin system controlling many cellular biological processes in eukaryotes. However, the roles of SCF ubiquitin ligases remain unclear in phytopathogenic Magnaporthe oryzae . Here, we cloned 24 F‐box proteins and confirmed that 17 proteins could interact with MoSkp1, showing their potential to participate in SCF complexes. To determine their functions, null mutants of 21 F‐box‐containing genes were created. Among them, the F‐box proteins MoFwd1, MoCdc4 and MoFbx15 were found to be required for growth, development and full virulence. Fluorescent‐microscopy observations demonstrated that both MoFbx15 and MoCdc4 were localized to the nucleus, compared with MoFwd1, which was distributed in the cytosol. MoCdc4 and MoFwd1 bound to MoSkp1 via the F‐box domain, the deletion of which abrogated their function. Race tube and qRT‐PCR assays confirmed that MoFwd1 was involved in circadian rhythm by regulating transcription and protein stability of the core circadian clock regulator MoFRQ . Moreover, MoFWD1 also orchestrates conidial germination by influencing conidial amino acids pools and oxidative stress release. Overall, our results indicate that SCF ubiquitin ligases play indispensable roles in development and pathogenicity in M. oryzae .

Seismic fragility analysis of deteriorating RC bridge columns with time-variant capacity index - Hu Cheng; Hong-Nan Li; Y. B. Yang; Dong-Sheng Wang (Bulletin of Earthquake Engineering, 2019)

Mitochondrial variation in small brown planthoppers linked to multiple traits and probably reflecting a complex evolutionary trajectory - Jing‐Tao Sun; Xing‐Zhi Duan; Ary A. Hoffmann; Yan Liu; Michael R. Garvin; Lei Chen; Gao Hu; Jin‐Cheng Zhou; Hai‐Jian Huang; Xiao‐Feng Xue; Xiao‐Yue Hong (Molecular Ecology, 2019)
While it has been proposed in several taxa that the mitochondrial genome is associated with adaptive evolution to different climatic conditions, making links between mitochondrial haplotypes and organismal phenotypes remains a challenge. Mitonuclear discordance occurs in the small brown planthopper (SBPH), Laodelphax striatellus, with one mitochondrial haplogroup (HGI) more common in the cold climate region of China relative to another form (HGII) despite strong nuclear gene flow, providing a promising model to investigate climatic adaptation of mitochondrial genomes. We hypothesized that cold adaptation through HGI may be involved, and considered mitogenome evolution, population genetic analyses, and bioassays to test this hypothesis. In contrast to our hypothesis, chill‐coma recovery tests and population genetic tests of selection both pointed to HGII being involved in cold adaptation. Phylogenetic analyses revealed that HGII is nested within HGI, and has three nonsynonymous changes in ND2 , ND5 and CYTB in comparison to HGI. These molecular changes likely increased mtDNA copy number, cold tolerance and fecundity of SBPH, particularly through a function‐altering amino acid change involving M114T in ND2 . Nuclear background also influenced fecundity and chill recovery (i.e., mitonuclear epistasis) and protein modelling indicates possible nuclear interactions for the two nonsynonymous changes in ND2 and CYTB . The high occurrence frequency of HGI in the cold climate region of China remains unexplained, but several possible reasons are discussed. Overall, our study points to a link between mtDNA variation and organismal‐level evolution and suggests a possible role of mitonuclear interactions in maintaining mtDNA diversity.

Application of Avaatech X-ray fluorescence core-scanning in Sr/Ca analysis of speleothems - Dong Li; Liangcheng Tan; Fei Guo; Yanjun Cai; Youbin Sun; Gang Xue; Xing Cheng; Hong Yan; Hai Cheng; R. Lawrence Edwards; Yongli Gao; Jessica Kelley (Science China Earth Sciences, 2019)

The Anti-bacterial and Anti-adherent Effects of Pentraxin-3 on Porcine Kidney Epithelial PK15 Cells Against Staphylococcus aureus Infection - Bao-Hong Lee; Wei-Hsuan Hsu; Cheng-Hui Lin (International Journal of Peptide Research and Therapeutics, 2019)

Phosphate adsorption from wastewater using ZnAl-LDO-loaded modified banana straw biochar - Yan-Hong Jiang; An-Yu Li; Hua Deng; Cheng-Hui Ye; Yi Li (Environmental Science and Pollution Research, 2019)

Effects of NaCl stress on growth of Portulaca oleracea and underlying mechanisms - Jin-Cheng Xing; Jing Dong; Mao-Wen Wang; Chong Liu; Bao-Quan Zhao; Zhu-Gui Wen; Xiao-Mei Zhu; Hai-Rong Ding; Xiao-Hui Zhao; Li-Zhou Hong (Brazilian Journal of Botany, 2019)

Digitizing and modeling of structural planes in fractured rock mass tunnel based on SfM - Shang-qu Sun; Li-ping Li; Cheng-shuai Qin; Hong-liang Liu; Yan-huan Zhang; Xing-zhi Ba (Arabian Journal of Geosciences, 2019)

Mitochondrial Gene Heterogeneity and Population Genetics of Haemaphysalis longicornis (Acari: Ixodidae) in China - Zhong-Bo Li; Yi-Tian Fu; Tian-Yin Cheng; Guo-Min Yao; Qiang-Hong Hou; Fen Li; Yu Zhao; Feng-Cai Zou; Guo-Hua Liu (Acta Parasitologica, 2019)

Overexpression and VIGS system for functional gene validation in oriental melon (Cucumis melo var. makuwa Makino) - Jing Jing Liao; Cheng Hui Wang; Qiao Juan Xing; Yue Peng Li; Xian Feng Liu; Hong Yan Qi (Plant Cell, Tissue and Organ Culture (PCTOC), 2019)

Silencing of Long Noncoding RNA SOX21-AS1 Relieves Neuronal Oxidative Stress Injury in Mice with Alzheimer’s Disease by Upregulating FZD3/5 via the Wnt Signaling Pathway - Lu Zhang; Yu Fang; Xuan Cheng; Ya-Jun Lian; Hong-Liang Xu (Molecular Neurobiology, 2019)

A novel SGNH family hydrolase Ali5 with thioesterase activity and a GNSL motif but without a classic GDSL motif from Altererythrobacter ishigakiensis - Li-Guo Hong; Shu-Ling Jian; Ying-Yi Huo; Hong Cheng; Xiao-Jian Hu; Jixi Li; Heng-Lin Cui; Xue-Wei Xu (Biotechnology Letters, 2019)

Zinc-Enriched Yeast Improves Learning and Memory Impairments in Zinc-Deficient Rats - Shuang-Qing Zhang; Hai-Bo Zhang; Qian Cheng; Ya-Min Zhu; Chang-Hong Xia; Yin-Hong Zhu; Yan Zhang (Biological Trace Element Research, 2019)

Elaboration in type, primary structure, and bioactivity of polysaccharides derived from mollusks - Ling Chong Wang; Liu Qing Di; Jun Song Li; Li Hong Hu; Jian Ming Cheng; Hao Wu (Critical Reviews in Food Science and Nutrition, 2019)

Correction to: A new species of Microterys (Hymenoptera: Encyrtidae) from Northeast China, parasitoid of Parthenolecanium corni (Bouché) (Hemiptera: Coccidae) - Guo-Hao Zu; Cheng-De Li; Yuan-Hong Wang (Phytoparasitica, 2019)

Effects of acclimation temperature on the thermal tolerance, hypoxia tolerance and swimming performance of two endangered fish species in China - Long-Yan Zhou; Shi-Jian Fu; Cheng Fu; Hong Ling; Xiu-Ming Li (Journal of Comparative Physiology B, 2019)

Long-term seasonal forecasting of a major migrant insect pest: the brown planthopper in the Lower Yangtze River Valley - Gao Hu; Ming-Hong Lu; Don R. Reynolds; Hai-Kou Wang; Xiao Chen; Wan-Cai Liu; Feng Zhu; Xiang-Wen Wu; Feng Xia; Miao-Chang Xie; Xia-Nian Cheng; Ka-Sing Lim; et al. (Journal of Pest Science, 2019)

Investigating suspended-sediment transport in a shallow lake using a three-dimensional hydrodynamic and sediment model - Wen-Cheng Liu; Hong-Ming Liu; Chih-Yu Chiu (Journal of Earth System Science, 2019)

Refined assessment of heavy metal-associated health risk due to the consumption of traditional animal medicines in humans - Tian-Tian Zuo; Yao-Lei Li; Huai-Zhen He; Hong-Yu Jin; Lei Zhang; Lei Sun; Fei Gao; Qi Wang; Yuan-Jun Shen; Shuang-Cheng Ma; Lang-Chong He (Environmental Monitoring and Assessment, 2019)

Effect of snowmelt infiltration on groundwater recharge in a seasonal soil frost area: a case study in Northeast China - Xinqiang Du; Min Fang; Hang Lv; Tingting Cheng; Peidong Hong; Chang Liu (Environmental Monitoring and Assessment, 2019)

The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration - Li Zhang; Jian-Hong Zhu; Xiong Zhang; Wen-Hsing Cheng (Biological Trace Element Research, 2019)