Striatal dopamine synthesis capacity and its association with negative symptoms upon resolution of positive symptoms in first-episode schizophrenia and delusional disorder - Stephanie M. Y. Wong; Y. N. Suen; Charlotte W. C. Wong; Sherry K. W. Chan; Christy L. M. Hui; W. C. Chang; Edwin H. M. Lee; Calvin P. W. Cheng; Garrett C. L. Ho; Gladys Goh Lo; Eric Y. L. Leung; Paul K. M. Au Yeung; et al. (Psychopharmacology, 2022)

Correction to: Matrine Treatment Blocks NogoA-Induced Neural Inhibitory Signaling Pathway in Ongoing Experimental Autoimmune Encephalomyelitis - Quan-Cheng Kan; Hui-Jun Zhang; Yuan Zhang; Xing Li; Yu-Ming Xu; Rodolfo Thome; Ming-Liang Zhang; Nan Liu; Yao-Juan Chu; Guang-Xian Zhang; Lin Zhu (Molecular Neurobiology, 2022)

Association between secondhand smoke and peripheral arterial disease: a meta-analysis of cross-sectional studies - Chih-Wei Wu; Hung-Yi Chuang; Kazuhiro Watanabe; Pei-Shan Wu; Hui-Chen Pan; Chao-Ling Wang; Chen-Cheng Yang; Chih-Hsing Hung; Chia-Yen Dai; Chi-Kung Ho; Norito Kawakami (International Archives of Occupational and Environmental Health, 2022)

Antibiotic of tetracycline can delay water absorption and germination of Brassica seeds even at low concentrations and it is dependent on seed inherent characteristics - Yuan Luo; Yuan Liu; Hui Zhang; Jie Liang; Haibo Zhang; Hongyan Cheng (Environmental Science and Pollution Research, 2022)

High Levels of 25-OH-Vitamin D and Copper in Pregnant Women with Abnormal Glucose Challenge Test - Chien-Hua Chiang; Wan-Ju Kung; Chien-Hung Lee; Yeong-Hwa Zen; Cheng-Fa Lee; Hui-Ru Yang; Ching-Chiang Lin; Yeou-Lih Huang (Biological Trace Element Research, 2022)

Effect of temperature on mudstone disintegration process revealed with image analysis - Luo-bin Yan; Srdjan Petrović; Cheng Huang; Chun-xia Xie; Hui-ming Zong; Milica Kašanin-Grubin (Journal of Mountain Science, 2022)

Quantifying soil nitrous oxide emissions in spring freezing-thawing period over different vegetation types in Northeast China - Bin Wu; Chang-cheng Mu; Hui Liu; Ya-kun Xu; Yue Zhang; Jia-shuo Yang; Wen-nian Xu (Journal of Mountain Science, 2022)

The tetrameric assembly of 2‐aminomuconic 6‐semialdehyde dehydrogenase is a functional requirement of cofactor NAD + binding - Qiuli Shi; Yanjuan Chen; Xinxin Li; Hui Dong; Cheng Chen; Zhihui Zhong; Cheng Yang; Guangfeng Liu; Dan Su (Environmental Microbiology, 2022)
Summary The bacterium Pseudomonas sp. AP‐3 is able to use the environmental pollutant 2‐aminophenol as its sole source of carbon, nitrogen, and energy. Eight genes (amnA, B, C, D, E, F, G, and H) encoding 2‐aminophenol metabolizing enzymes are clustered into a single operon. 2‐Aminomuconic 6‐semialdehyde dehydrogenase (AmnC), a member of the aldehyde dehydrogenase (ALDH) superfamily, is responsible for oxidizing 2‐aminomuconic 6‐semialdehyde to 2‐aminomuconate. In contrast to many other members of the ALDH superfamily, the structural basis of the catalytic activity of AmnC remains elusive. Here, we present the crystal structure of AmnC, which displays a homotetrameric quaternary assembly that is directly involved in its enzymatic activity. The tetrameric state of AmnC in solution was also presented using small‐angle X‐ray scattering. The tetramerization of AmnC is mediated by the assembly of a protruding hydrophobic beta‐strand motif and residues V121 and S123 located in the NAD + ‐binding domain of each subunit. Dimeric mutants of AmnC dramatically lose NAD + binding affinity and failed to oxidize the substrate analogue 2‐hydroxymuconate‐6‐semialdehyde to α‐hydroxymuconic acid, indicating that tetrameric assembly of AmnC is functional requirement.

Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities - Lu Luo; Jun Yang; Cheng Wang; Jie Wu; Yafang Li; Xu Zhang; Hui Li; Hui Zhang; Yumei Zhou; Aiping Lu; Shilin Chen (Science China Life Sciences, 2022)

Genetic dissection of heterotic loci associated with plant weight by Graded pool-seq in heading Chinese cabbage (Brassica rapa) - Lixin Yue; Rifei Sun; Guoliang Li; Feng Cheng; Limin Gao; Qinghua Wang; Shifan Zhang; Hui Zhang; Shujiang Zhang; Fei Li (Planta, 2022)

Extracellular vesicles derived from human Sertoli cells: characterizations, proteomic analysis, and miRNA profiling - Xiao-Hui Tan; Sheng-Ji Gu; Wen-Jie Tian; Wen-Peng Song; Yang-Yang Gu; Yi-Ming Yuan; Xue-Song Li; Zhong-Cheng Xin; Sae Woong Kim; Rui-Li Guan; Woong Jin Bae (Molecular Biology Reports, 2022)

TREM-2 mediates dendritic cell–induced NO to suppress Th17 activation and ameliorate chronic kidney diseases - Ching-Cheng Lin; Ti-Yung Chang; Yong-Chen Lu; Yun-Syuan Wu; Wei Huang; Wei-Chi Lo; Guan-Fu Liu; Wei-Chan Hsu; Pamela S. Ohashi; Tak W. Mak; Jong-Ling Fuh; Hui-Chen Chen; et al. (Journal of Molecular Medicine, 2022)

Use of piggyBac Transposon System Constructed Murine Breast Cancer Model for Reporter Gene Imaging and Characterization of Metastatic Tumor Cells - Ying-Ling Chen; Yung-Cheng Wang; Kuei-Yuan Hou; Min-Ying Lin; Yu-Chuan Lin; Hui-Yen Chuang; Yi-Jang Lee (Journal of Medical and Biological Engineering, 2022)

Development and Application of Rock Fracture Propagation Numerical Simulation System - Hui Wang; Hang Zhou; Shichang Shang; Cheng Jiang (Geotechnical and Geological Engineering, 2022)

Mixed carbonate-siliciclastic reservoir characterization and hydrocarbon accumulation process of the Ganchaigou area in the western Qaidam Basin, Tibet Plateau - Hai Wu; Hui Liu; Long Wang; Lili Gui; Cheng Yang; Lixin Wang (Carbonates and Evaporites, 2022)

Flow-slide characteristics and failure mechanism of shallow landslides in granite residual soil under heavy rainfall - Hui-lin Bai; Wen-kai Feng; Shuang-quan Li; Long-zhen Ye; Zhong-teng Wu; Rui Hu; Hong-chuan Dai; Yun-peng Hu; Xiao-yu Yi; Peng-cheng Deng (Journal of Mountain Science, 2022)

Relationships of multiple metals exposure, global DNA methylation, and urothelial carcinoma in central Taiwan - Hui-Tsung Hsu; Hui-Ling Lee; Hsu-Hui Cheng; Chao-Hsiang Chang; Chiu-Shong Liu; Po-Jen Hsiao; Han Chang; Chi-Shun Lien; Mu-Chi Chung; Chi-Jung Chung (Archives of Toxicology, 2022)

Alteromonas oceanisediminis sp. nov., isolated from deep-sea sediment - Xiao-Yu Zhang; Zhen Wang; Jun-Hui Cheng; Hui-Hui Fu; Yu-Zhong Zhang; Xiu-Lan Chen; Xi-Ying Zhang; Xiao-Yan Song; Yu-Qiang Zhang; Fei Xu (Archives of Microbiology, 2022)

Exploiting Sentinel-1 data and machine learning–based random forest for collectively mapping rice fields in Taiwan - Nguyen-Thanh Son; Chi-Farn Chen; Cheng-Ru Chen; Youg-Sin Cheng; Piero Toscano; Chein-Hui Syu; Horng-Yuh Guo; Shu-Ling Chen; Tsang-Sen Liu; Yi-Ting Zhang; Huan-Sheng Lin; Shih-Hsiang Chen; et al. (Applied Geomatics, 2022)

NURBS-Based Parametric Design for Ship Hull Form - Hui Zhou; Baiwei Feng; Zuyuan Liu; Haichao Chang; Xide Cheng (Journal of Marine Science and Engineering, 2022)
Recently, the NURBS technique has been widely used in the 3D design software for ships. However, in most research, the NURBS technique is only applied to the mathematical representation of hull curves and surfaces, and the parametric deformation of hull surfaces based on geometric feature parameters is less understood. The aims of this paper are to establish the parametric design process of hull surfaces through the classification of geometric feature parameters and the design of feature curves, apply the NURBS technique to the parametric geometric modeling of hull curves and surfaces, and finally achieve the parametric deformation of hull surfaces driven by geometric feature parameters and develop the parametric deformation software. Taking the Series 60 ship as an example, we first analyze the hull geometric features and parameters, then design the longitudinal feature curves and cross-section curves based on the NURBS technique and establish the correlation between them, and finally generate the smooth hull surface by the skinning technique to achieve the parametric geometric deformation of the Series 60 ship. The research in this paper shows that the smoothness of the surfaces generated by the NURBS-based parametric design method is good. Additionally, the extracted feature parameters have a clear geometric meaning and can automatically generate hull forms to meet the design requirements quickly and effectively, which has some practical engineering value.

Framework for Automatic Coral Reef Extraction Using Sentinel-2 Image Time Series - Qizhi Zhuang; Jian Zhang; Liang Cheng; Hui Chen; Yanruo Song; Song Chen; Sensen Chu; Shengkun Dongye; Manchun Li (Marine Geodesy, 2022)

Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide - Ting Jiang; Geng Xia; Bo Yang; Hong-wei Zhang; Yue-shan Yin; Cheng-wei Tang; Jin-hui Yang (Tissue Engineering and Regenerative Medicine, 2022)
Background: Endotoxemia is related to worse clinical outcomes in acute liver failure (ALF), but its management remains unsatisfactory. In this study, we aimed to assess whether the application of bone marrow mesenchymal stem cells (BMSCs) could eliminate endotoxemia and protect rats against ALF induced by thioacetamide (TAA). Methods: BMSCs were isolated from rats and identified by the specific morphology, differentiation potential, and surface markers. The optimal dose of TAA for this study was explored and TAA-induced ALF rats were randomized to three groups: the normal control group (Saline), ALF group (TAA + Saline), and BMSCs-treated group (TAA + BMSCs). The intestinal migration and differentiation of BMSCs was tracked in vivo , and intestinal permeability, endotoxin and inflammatory cytokines, histology, and mortality were analyzed. Moreover, we added the inhibitor of the PI3K/AKT/mTOR signaling pathway into the co-culture system of BMSCs with enterocytes and then performed CK and Villin expression experiments to assess the role of PI3K/AKT/mTOR signal pathway in the intestinal differentiation of BMSCs. Results: BMSCs migrated to the intestinal injury sites and differentiated into enterocytes, intestinal permeability was decreased compared with the ALF group. The higher expression of endotoxin and inflammatory cytokines were reversed after BMSCs transplantation in rats with ALF. Mortality and intestinal lesion were significantly decreased. Blocking the PI3K/AKT/mTOR signal pathway inhibited BMSCs’ intestinal differentiation in vitro . Conclusion: BMSCs can eliminate endotoxemia and reduce mortality in rats with ALF, and the PI3K/AKT/mTOR signal pathway is involved in intestinal differentiation. BMSCs transplantation could be a potential candidate for the treatment of endotoxemia in ALF.

Global divergent trends of algal blooms detected by satellite during 1982–2018 - Chong Fang; Kaishan Song; Hans W Paerl; Pierre‐Andre Jacinthe; Zhidan Wen; Ge Liu; Hui Tao; Xiaofeng Xu; Tiit Kutser; Zongming Wang; Hongtao Duan; Kun Shi; et al. (Global Change Biology, 2022)
Algal blooms (ABs) in inland lakes have caused adverse ecological effects, and health impairment of animals and humans. We used archived Landsat images to examine ABs in lakes (>1 km 2 ) around the globe over a 37‐year time span (1982–2018). Out of the 176032 lakes with area >1 km 2 detected globally, 863 were impacted by ABs, 708 had sufficiently long records to define a trend, and 66% exhibited increasing trends in frequency ratio (FRQR, ratio of the number of ABs events observed in a year in a given lake to the number of available Landsat images for that lake) or area ratio (AR, ratio of annual maximum area covered by ABs observed in a lake to the surface area of that lake), while 34% showed a decreasing trend. Across North America, an intensification of ABs severity was observed for FRQR ( p p p p

Hippocampal SIRT1-Mediated Synaptic Plasticity and Glutamatergic Neuronal Excitability Are Involved in Prolonged Cognitive Dysfunction of Neonatal Rats Exposed to Propofol - Lin-Hui Ma; Jie Wan; Jing Yan; Ning Wang; Yan-Ping Liu; Hai-Bi Wang; Cheng-Hua Zhou; Yu-Qing Wu (Molecular Neurobiology, 2022)

CAV1 is a prognostic predictor for patients with idiopathic pulmonary fibrosis and lung cancer - Dongdong Yin; Jiayang Qiu; Suxia Hu; Longqiang Cheng; Hui Li; Xingpu Cheng; Shun Wang; Jun Lu (Journal of Biosciences, 2022)

Nanoscale zero-valent iron alters physiological, biochemical, and transcriptomic response of nonylphenol-exposed algae (Dictyosphaerium sp.) - Ying Jiang; Linna Du; Qilu Cheng; Zhuo Jin; Cai Hui; Yuhua Zhao; Hui Jiang; Ligen Xu (Environmental Science and Pollution Research, 2022)

Photocatalytic degradation of imidacloprid by optimized Bi2WO6/NH2-MIL-88B(Fe) composite under visible light - Mao-Long Chen; Tian-Hui Lu; Shan-Shan Li; Li Wen; Zhou Xu; Yun-Hui Cheng (Environmental Science and Pollution Research, 2022)

A comprehensive exploration on the health risk quantification assessment of soil potentially toxic elements from different sources around large-scale smelting area - Chang-Chen Huang; Li-Mei Cai; Yao-Hui Xu; Luo Jie; Lai-Guo Chen; Guo-Cheng Hu; Hui-Hao Jiang; Xu-Bang Xu; Jing-Xian Mei (Environmental Monitoring and Assessment, 2022)

Migration and abiotic transformation of estrone (E1) and estrone-3-sulfate (E1-3S) during soil column transport - Banghao Du; Weiwei Yu; Lun Yang; Gongduan Fan; Shuo Yang; Hui Jiang; Shenglan Bi; Cheng Yu (Environmental Geochemistry and Health, 2022)

Characterization and genomic analysis of a Demerecviridae phage SP76 with lytic multiple-serotypes of Salmonella - Hui Wang; Yun Shen; Pei LI; Yuyi Xiao; Yanxiu Li; Xiapei Hu; Zhuohao Wang; Zile Cheng; Zitong Wang; Qingxin Liu; Si Qin; Xiang Huo; et al. (Archives of Microbiology, 2022)

Endosomal sorting complexes required for transport‐0 ( ESCRT ‐0) are essential for fungal development, pathogenicity, autophagy and ER ‐phagy in Magnaporthe oryzae - Li‐Xiao Sun; Hui Qian; Meng‐Yu Liu; Ming‐Hua Wu; Yun‐Yun Wei; Xue‐Ming Zhu; Jian‐Ping Lu; Fu‐Cheng Lin; Xiao‐Hong Liu (Environmental Microbiology, 2022)
Summary Magnaporthe oryzae is an important plant pathogen that causes rice blast. Hse1 and Vps27 are components of ESCRT‐0 involved in the multivesicular body (MVB) sorting pathway and biogenesis. To date, the biological functions of ESCRT‐0 in M. oryzae have not been determined. In this study, we identified and characterized Hse1 and Vps27 in M. oryzae . Disruption of MoHse1 and MoVps27 caused pleiotropic defects in growth, conidiation, sexual development and pathogenicity, thereby resulting in loss of virulence in rice and barley leaves. Disruption of MoHse1 and MoVps27 triggered increased lipidation of MoAtg8 and degradation of GFP‐MoAtg8, indicating that ESCRT‐0 is involved in the regulation of autophagy. ESCRT‐0 was determined to interact with coat protein complex II (COPII), a regulator functioning in homeostasis of the endoplasmic reticulum (ER homeostasis), and disruption of MoHse1 and MoVps27 also blocked activation of the unfolded protein response (UPR) and autophagy of the endoplasmic reticulum (ER‐phagy). Overall, our results indicate that ESCRT‐0 plays critical roles in regulating fungal development, virulence, autophagy and ER‐phagy in M. oryzae .

Prevalence, complete genome, and metabolic potentials of a phylogenetically novel cyanobacterial symbiont in the coral‐killing sponge, Terpios hoshinota - Yu‐Hsiang Chen; Hsing‐Ju Chen; Cheng‐Yu Yang; Jia‐Ho Shiu; Daphne Z. Hoh; Pei‐Wen Chiang; Wenhua Savanna Chow; Chaolun Allen Chen; Tin‐Han Shih; Szu‐Hsien Lin; Chi‐Ming Yang; James Davis Reimer; et al. (Environmental Microbiology, 2022)
Summary Terpios hoshinota is an aggressive, space‐competing sponge that kills various stony corals. Outbreaks of this species have led to intense damage to coral reefs in many locations. Here, the first large‐scale 16S rRNA gene survey across three oceans revealed that bacteria related to the taxa Prochloron , Endozoicomonas , SAR116, Ruegeria , and unclassified Proteobacteria were prevalent in T . hoshinota . A Prochloron ‐related bacterium was the most dominant and prevalent cyanobacterium in T . hoshinota . The complete genome of this uncultivated cyanobacterium and pigment analysis demonstrated that it has phycobiliproteins and lacks chlorophyll b , which is inconsistent with the definition of Prochloron . Furthermore, the cyanobacterium was phylogenetically distinct from Prochloron , strongly suggesting that it should be a sister taxon to Prochloron . Therefore, we proposed this symbiotic cyanobacterium as a novel species under the new genus Candidatus Paraprochloron terpiosi. Comparative genomic analyses revealed that ‘Paraprochloron’ and Prochloron exhibit distinct genomic features and DNA replication machinery. We also characterized the metabolic potentials of ‘Paraprochloron terpiosi’ in carbon and nitrogen cycling and propose a model for interactions between it and T. hoshinota . This study builds a foundation for the study of the T . hoshinota microbiome and paves the way for better understanding of ecosystems involving this coral‐killing sponge.

Anticyclonic Eddy Driving Significant Changes in Prokaryotic and Eukaryotic Communities in the South China Sea - Fulin Sun; Xiaomin Xia; Meinhard Simon; Youshao Wang; Hui Zhao; Cuici Sun; Hao Cheng; Yutu Wang; Shuibo Hu; Jiao Fei; Meilin Wu (Frontiers in Marine Science, 2022)
Mesoscale eddies play an important role in ocean energy and material transport. However, the effect of eddies on bacterial and eukaryotic community and their ecological effects remains unclear, regarding anticyclonic eddies (ACE). In this study, bacterial and eukaryotic community composition was examined across an ACE in the South China Sea, using high-throughput sequencing of the 16S rRNA and 18S rRNA gene. Environmental variables reflected the hydrographic characteristics of the ACE, which enhanced bacterial diversity and eukaryotic diversity in most water layers, relative to adjacent regions. Principal component analysis (PCoA) showed that bacterial and eukaryotic communities had certain different compositions between inside and outside the eddy above 75 m water. An obvious effect of the ACE was the increase in abundance and depth distribution of small photosynthetic and heterotrophic bacteria, such as SAR11, Prochlorococcus , Rhodospirillales and Oceanospirillales. While ACE decreased the relative abundance of nutrient-rich phytoplankton (Bacillariophyta and Mamiellophyceae), resulted in more growth space for other eukaryotes that prefer oligotrophic environment (especially Fungi, Dictyochophyceae, and Synurophyceae). Canonical correlation analysis (CCA) showed temperature, salinity, nitrate, phosphate and nitrite had significantly affected on microbial community. The special environment of ACE (especially temperature) shaped the composition of its specific microbe. This study shed important light on the effect of ACEs on environmental conditions to impact marine ecosystem structure.

An autopolyploid-suitable polyBSA-seq strategy for screening candidate genetic markers linked to leaf blight resistance in sugarcane - Zhoutao Wang; Hui Ren; Chao Pang; Guilong Lu; Fu Xu; Wei Cheng; Youxiong Que; Liping Xu (Theoretical and Applied Genetics, 2022)

LncRNA Riken Attenuated Sevoflurane-Induced Neuroinflammation by Regulating the MicroRNA-101a/MKP-1/JNK Pathway - Qi Hou; Shuai Li; Bo Zhang; Huaqing Chu; Cheng Ni; Xuejie Fei; Hui Zheng (Neurotoxicity Research, 2022)

Correction to: Clinical profile of children with parechovirus meningitis in Singapore - Jessica Hui Yin Tan; Chew Thye Choong; Nancy Wen Sim Tee; Chia Yin Chong; Koh Cheng Thoon; Matthias Maiwald; Elis Yue Xian Lee; Melody Si Shan Tan; Natalie Woon Hui Tan (Journal of NeuroVirology, 2022)

Clinical profile of children with parechovirus meningitis in Singapore - Jessica Hui Yin Tan; Chew Thye Choong; Nancy Wen Sim Tee; Chia Yin Chong; Koh Cheng Thoon; Matthias Maiwald; Elis Yue Xian Lee; Melody Si Shan Tan; Natalie Woon Hui Tan (Journal of NeuroVirology, 2022)

Decreased incidence of acute hemorrhagic conjunctivitis associated with enhanced public health intervention during the COVID-19 epidemic in China, 2020 - Li Zhang; Xiangyu Guo; Hui Jiang; Na Zhao; Wei Cheng; Wangli Xu; Shelan Liu (Archives of Virology, 2022)

Identifying Priority Conservation Areas of Largehead Hairtail (Trichiurus japonicus) Nursery Grounds in the East China Sea - Zunlei Liu; Yan Jin; Liping Yan; Yi Zhang; Hui Zhang; Chuyi Shen; Linlin Yang; Jiahua Cheng (Frontiers in Marine Science, 2022)
Identifying the spatio-temporal distribution hotspots of fishes and allocating priority conservation areas could facilitate the spatial planning and efficient management. As a flagship commercial fishery species, Largehead hairtail ( Trichiurus japonicus ) has been over-exploited since the early 2000s. Therefore, the spatio-temporal management of largehead hairtail nursery grounds could effective help its recovery. This study aims to predict juvenile largehead hairtail distribution patterns and identify priority conservation areas for nursery grounds. A two-stage hierarchical Bayesian spatio-temporal model was applied on independent scientific survey data (Catch per unit effort, CPUE) and geographic/physical variables (Depth, Distance to the coast, Sea bottom temperature, Dissolved oxygen concentration and Net primary production) to analyze the probability of occurrence and abundance distribution of juvenile largehead hairtail. We assessed the importance of each variable for explaining the occurrence and abundance. Using persistence index, we measured the robustness of hotspots and identified persistent hotspots for priority conservation areas. Selected models showed good predictive capacity on occurrence probability (AUC = 0.81) and abundance distribution ( r = 0.89) of juvenile largehead hairtail. Dissolved oxygen, net primary production, and sea bottom temperature significantly affected the probability of occurrence, while distance to the coast also affected the abundance distribution. Three stable nursery grounds were identified in Zhejiang inshore waters, the largest one was located on the east margin of the East China Sea hairtail national aquatic germplasm resources conservation zones (TCZ), suggesting that the core area of nursery grounds occurs outside the protected areas. Therefore, recognition of these sites and their associated geographic/oceanic attributes provides clear targets for optimizing largehead hairtail conservation efforts in the East China Sea. We suggested that the eastern and southern areas of TCZ should be included in conservation planning for an effective management within a network of marine protected areas.

Identification of A-to-I RNA editing profiles and their clinical relevance in lung adenocarcinoma - Cheng Wang; Mingtao Huang; Congcong Chen; Yuancheng Li; Na Qin; Zijian Ma; Jingyi Fan; Linnan Gong; Hui Zeng; Liu Yang; Xianfeng Xu; Jun Zhou; et al. (Science China Life Sciences, 2022)

N-acetylcysteine alleviates pulmonary inflammatory response during benzo[a]pyrene-evoked acute lung injury - Hui Zhao; Lin Fu; Hui-Xian Xiang; Ying Xiang; Meng-Die Li; Bian-Bian Lv; Zhu-Xia Tan; Lan Gao; Cheng Zhang; De-Xiang Xu (Environmental Science and Pollution Research, 2022)

Not out of the woods yet: Signatures of the prolonged negative genetic consequences of a population bottleneck in a rapidly re‐expanding wader, the black‐faced spoonbill Platalea minor - Shou‐Hsien Li; Yang Liu; Chia‐Fen Yeh; Yuchen Fu; Carol K. L. Yeung; Chun‐Cheng Lee; Chi‐Cheng Chiu; Tung Hui Kuo; Fang‐Tse Chan; Yu‐Chia Chen; Wen‐Ya Ko; Cheng‐Te Yao (Molecular Ecology, 2022)
The long‐term persistence of a population which has suffered a bottleneck partly depends on how historical demographic dynamics impacted its genetic diversity and the accumulation of deleterious mutations. Here we provide genomic evidence for the genetic effect of a recent population bottleneck in the endangered black‐faced spoonbill ( Platalea minor ) after its rapid population recovery. Our data suggest that the bird's effective population size, N e , had been relatively stable (7500–9000) since 22,000 years ago; however, a recent brief yet severe bottleneck ( N e = 20) which we here estimated to occur around the 1940s wiped out >99% of its historical N e in roughly three generations. Despite a >15‐fold population recovery since 1988, we found that black‐faced spoonbill population has higher levels of inbreeding (7.4 times more runs of homozygosity) than its sister species, the royal spoonbill ( P. regia ), which is not thought to have undergone a marked population contraction. Although the two spoonbills have similar levels of genome‐wide genetic diversity, our results suggest that selection on more genes was relaxed in the black‐faced spoonbill; moreover individual black‐faced spoonbills carry more putatively deleterious mutations (Grantham's score > 50), and may therefore express more deleterious phenotypic effects than royal spoonbills. Here we demonstrate the value of using genomic indices to monitor levels of genetic erosion, inbreeding and mutation load in species with conservation concerns. To mitigate the prolonged negative genetic effect of a population bottleneck, we recommend that all possible measures should be employed to maintain population growth of a threatened species.

Cytotoxic activity of phytochemicals from Garcinia mangostana L. and G. benthamiana (Planch. & Triana) Pipoly against breast cancer cells - Irene See; Gwendoline Cheng Lian Ee; Vivien Yi Mian Jong; Soek Sin Teh; Carlos L. Céspedes Acuña; Siau Hui Mah (Natural Product Research, 2021)

Understanding the “SMART” features of hematopoietic stem cells and beyond - Shiru Yuan; Guohuan Sun; Yawen Zhang; Fang Dong; Hui Cheng; Tao Cheng (Science China Life Sciences, 2021)

Fiber-optic wireless sensor network using ultra-weak fiber Bragg gratings for vertical subsurface deformation monitoring - Su-Ping Liu; Bin Shi; Kai Gu; Cheng-Cheng Zhang; Jian-Hui He; Jing-Hong Wu; Guang-Qing Wei (Natural Hazards, 2021)

Correction to: μ-Opioid Receptor–Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation - Hui Gao; Yuxin Zhang; Yansong Li; Haiqing Chang; Bo Cheng; Na Li; Wei Yuan; Shuang Li; Qiang Wang (Molecular Neurobiology, 2021)

Neonatal Anesthesia by Ketamine in Neonatal Rats Inhibits the Proliferation and Differentiation of Hippocampal Neural Stem Cells and Decreases Neurocognitive Function in Adulthood via Inhibition of the Notch1 Signaling Pathway - He Huang; Chao Zhao; Qian Hu; Qiang Liu; Yi-Man Sun; Chen Chen; Hui Huang; Cheng-Hua Zhou; Yu-Qing Wu (Molecular Neurobiology, 2021)

Long non-cording RNA XIST promoted cell proliferation and suppressed apoptosis by miR-423-5p/HMGA2 axis in diabetic nephropathy - Hui Chen; Yuan Guo; Xingbo Cheng (Molecular and Cellular Biochemistry, 2021)

Occurrence, source apportionment, and carcinogenic risk assessment of polycyclic aromatic hydrocarbons in urban road dusts in Shanghai - Xue-Tong Wang; Rui Fu; Ying Zhou; Cheng-Lin Wang; Guo-Fa Ren; Xiao-Li Wang; Hui Li (Environmental Science and Pollution Research, 2021)

Correction to: Ocean acidification alters the thermal performance curves of brooded larvae from the reef coral Pocillopora damicornis - Lei Jiang; You-Fang Sun; Yu-Yang Zhang; Yuan Tian; Xin-Ming Lei; Guo-Wei Zhou; Tao Yuan; Xiang-Cheng Yuan; Sheng Liu; Hui Huang (Coral Reefs, 2021)

Investigation on the statistical characteristics of geoelectric field seismic anomalies in the North–South seismic belt of Chinese mainland - Hou Ze-Yu; An Zhang-Hui; Fan Ying-Ying; Tan Da-Cheng; Fu A-Long; Wei Lei (Acta Geophysica, 2021)

Household environmental microbiota influences early‐life eczema development - Le Duc Huy Ta; Carina Jing Xuan Tay; Christophe Lay; Paola Florez de Sessions; Cheryl Pei Ting Tan; Michelle Jia Yu Tay; Hui Xing Lau; Atiqa Binte Zulkifli; Gaik Chin Yap; Elizabeth Huiwen Tham; Eliza Xin Pei Ho; Anne Eng Neo Goh; et al. (Environmental Microbiology, 2021)
Summary Exposure to a diverse microbial environment during pregnancy and early postnatal period is important in determining predisposition towards allergy. However, the effect of environmental microbiota exposure during preconception, pregnancy and postnatal life on development of allergy in the child has not been investigated so far. In the S‐PRESTO (Singapore PREconception Study of long Term maternal and child Outcomes) cohort, we collected house dust during all three critical window periods and analysed microbial composition using 16S rRNA gene sequencing. At 6 and 18 months, the child was assessed for eczema by clinicians. In the eczema group, household environmental microbiota was characterized by presence of human‐associated bacteria Actinomyces , Anaerococcus, Finegoldia, Micrococcus, Prevotella and Propionibacterium at all time points, suggesting their possible contributions to regulating host immunity and increasing the susceptibility to eczema. In the home environment of the control group, putative protective effect of an environmental microbe Planomicrobium ( Planococcaceae family) was observed to be significantly higher than that in the eczema group. Network correlation analysis demonstrated inverse relationships between beneficial Planomicrobium and human‐associated bacteria ( Actinomyces , Anaerococcus, Finegoldia, Micrococcus, Prevotella and Propionibacterium ). Exposure to natural environmental microbiota may be beneficial to modulate shed human‐associated microbiota in an indoor environment.

Dammarane-type saponins from Gynostemma pentaphyllum and their cytotoxicities - Wei-Ye Cui; Yulian Jin; Hui Liu; Ma-Li Zu; Xin-Fang Zhai; Ce Yang; Yu-Long Gu; Yong Cheng; Xiang-Lan Piao (Natural Product Research, 2021)

The chemical profile and biological activity of different extracts of Sapindus mukorossi Gaertn. against Cutibacterium acnes - Min-Ping Wei; Jin-Dan Qiu; Lu Li; Yun-Fei Xie; Ya-Hui Guo; Hang Yu; Yu-Liang Cheng; He Qian; Wei-Rong Yao (Natural Product Research, 2021)

Isolation of two sesquiterpene glycosides from Sapindus mukorossi Gaertn. with cytotoxic properties and analysis of their mechanism based on network pharmacology - Min-ping Wei; Xiao-wen Zhu; Hang Yu; Yun-fei Xie; Ya-hui Guo; Yu-liang Cheng; He Qian; Wei-rong Yao (Natural Product Research, 2021)

Cytotoxic triterpenoid glycosides from leaves of Cyclocarya paliurus - Hui-Hui Sun; Wen-Yan Lv; Jie Tan; Yu-Cheng Tang; Hui Zhu; Jian-Bo Qu; Jing Li; Jian-Ping Wu; Xi-Wen Chang; Zhi-Chun Yang; Wen-Xuan Wang; Zu-Hui Chen; et al. (Natural Product Research, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

Divergence in the Aquilegia ecalcarata complex is correlated with geography and climate oscillations: Evidence from plastid genome data - Cheng Xue; Fang‐Dong Geng; Jiao‐Jie Li; Dan‐Qing Zhang; Fei Gao; Lei Huang; Xiao‐Hui Zhang; Ju‐Qing Kang; Jian‐Qiang Zhang; Yi Ren (Molecular Ecology, 2021)
Quaternary climate oscillations and geographical heterogeneity play important roles in determining species and genetic diversity distribution patterns, but how these factors affect the migration and differentiation of East Asian plants species at the population level remains poorly understood. The Aquilegia ecalcarata complex, a group that originated in the Late Tertiary and is widely distributed throughout East Asia, displays high genetic variation that is suitable for studying elaborate phylogeographic patterns and demographic history related to the impact of Quaternary climate and geography. We used plastid genome data from 322 individuals in 60 populations of the A . ecalcarata complex to thoroughly explore the impact of Quaternary climate oscillations and geography on the phylogeographic patterns and demographic history of the A . ecalcarata complex through a series of phylogenetic, divergence time estimation, and demographic history analyses. The dry, cold climate and frequent climate oscillations that occurred during the early Pleistocene and the Mid‐Pleistocene transition led to the differentiation of the A . ecalcarata complex, which was isolated in various areas. Geographically, the A . ecalcarata complex can be divided into Eastern and Western Clades and five subclades, which conform to the divergence of the East Asian flora. Our results clearly show the impact of Quaternary climate and geography on evolutionary history at the population level. These findings promote the understanding of the relationship between plant genetic differentiation and climate and geographical factors of East Asia at the population level.

Abundance and Characteristics of Microplastics in Seawater and Corals From Reef Region of Sanya Bay, China - Xinming Lei; Hao Cheng; Yong Luo; Yuyang Zhang; Lei Jiang; Youfang Sun; Guowei Zhou; Hui Huang (Frontiers in Marine Science, 2021)
Microplastics (MPs) contamination is widespread in the coral reef ecosystems leading to the exposure of both corals and other biotas. Knowledge gaps still exist concerning patterns in MPs abundance spatially. This work quantified the MPs abundance and characteristics in the seawater and corals in the Sanya Bay, Hainan Island. MPs abundance was detected in the seawater and coral samples ranging from 15.50 to 22.14 items L –1 , and 0.01 to 3.60 items polyp –1 , respectively. We found the predominant size and type of MPs in seawater and corals were smaller than 2 mm and fiber. Further analysis revealed that the characteristics of MPs in the corals were significantly different from those in the seawater environment, indicating that the MPs are selectively enriched in corals. Furthermore, the MPs particles ingested and retained in coral tissue may be related to the polyp size. This study shows that MPs are present in the whole coral reef region and the coral community structure would be potentially harmed by these contaminants.

Single-cell transcriptomes of peripheral blood cells indicate and elucidate severity of COVID-19 - Xiaowei Xie; Xuelian Cheng; Gaoxiang Wang; Biao Zhang; Mengyao Liu; Liting Chen; Hui Cheng; Sha Hao; Jianfeng Zhou; Ping Zhu; Tao Cheng (Science China Life Sciences, 2021)

Comparing the clinical outcomes across different sodium/glucose cotransporter 2 (SGLT2) inhibitors in heart failure patients: a systematic review and network meta-analysis of randomized controlled trials - Yao Hao Teo; Celine Shuen Yin Yoong; Nicholas L. Syn; Yao Neng Teo; Jia Yang Alex Cheong; Yoke-Ching Lim; Chi-Hang Lee; Tiong-Cheng Yeo; Ping Chai; Raymond C. C. Wong; Weiqin Lin; Ching-Hui Sia (European Journal of Clinical Pharmacology, 2021)

Ocean acidification alters the thermal performance curves of brooded larvae from the reef coral Pocillopora damicornis - Lei Jiang; You-Fang Sun; Yu-Yang Zhang; Yuan Tian; Xin-Ming Lei; Guo-Wei Zhou; Tao Yuan; Xiang-Cheng Yuan; Sheng Liu; Hui Huang (Coral Reefs, 2021)

Plasticity of symbiont acquisition in new recruits of the massive coral Platygyra daedalea under ocean warming and acidification - Lei Jiang; Guo-Wei Zhou; Yu-Yang Zhang; Xin-Ming Lei; Tao Yuan; Ming-Lan Guo; Xiang-Cheng Yuan; Jian-Sheng Lian; Sheng Liu; Hui Huang (Coral Reefs, 2021)

Functional abnormalities of striatum are related to the season-specific effect on schizophrenia - Hui He; Huan Cao; Binxin Huang; Manxi He; Chi Ma; Dezhong Yao; Cheng Luo; Gang Yao; Mingjun Duan (Brain Imaging and Behavior, 2021)

Experimental study on integrated and autonomous conductivity-temperature-depth (CTD) sensor applied for underwater glider - Bin Lv; Hai-lin Liu; Yi-fan Hu; Cheng-xuan Wu; Jie Liu; Hai-jing He; Jie Chen; Jian Yuan; Zhao-wen Zhang; Lin Cao; Hui Li (Marine Georesources & Geotechnology, 2021)

Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica) - Hui Zhi; Qiang He; Sha Tang; Junjun Yang; Wei Zhang; Huifang Liu; Yanchao Jia; Guanqing Jia; Aiying Zhang; Yuhui Li; Erhu Guo; Ming Gao; et al. (Theoretical and Applied Genetics, 2021)

How are typical urban sewage treatment technologies going in China: from the perspective of life cycle environmental and economic coupled assessment - Hui Jiang; Qiang Jin; Panpan Cheng; Ming Hua; Zhen Ye (Environmental Science and Pollution Research, 2021)

Complex analysis of the personalized pharmacotherapy in the management of COVID-19 patients and suggestions for applications of predictive, preventive, and personalized medicine attitude - Lei-Yun Wang; Jia-Jia Cui; Qian-Ying OuYang; Yan Zhan; Yi-Min Wang; Xiang-Yang Xu; Lu-Lu Yu; Hui Yin; Yang Wang; Chen-Hui Luo; Cheng-Xian Guo; Ji-Ye Yin (EPMA Journal, 2021)
Aims Coronavirus disease 2019 (COVID-19) is rapidly spreading worldwide. Drug therapy is one of the major treatments, but contradictory results of clinical trials have been reported among different individuals. Furthermore, comprehensive analysis of personalized pharmacotherapy is still lacking. In this study, analyses were performed on 47 well-characterized COVID-19 drugs used in the personalized treatment of COVID-19. Methods Clinical trials with published results of drugs use for COVID-19 treatment were collected to evaluate drug efficacy. Drug-to-Drug Interactions (DDIs) were summarized and classified. Functional variations in actionable pharmacogenes were collected and systematically analysed. “Gene Score” and “Drug Score” were defined and calculated to systematically analyse ethnicity-based genetic differences, which are important for the safer use of COVID-19 drugs. Results Our results indicated that four antiviral agents (ritonavir, darunavir, daclatasvir and sofosbuvir) and three immune regulators (budesonide, colchicine and prednisone) as well as heparin and enalapril could generate the highest number of DDIs with common concomitantly utilized drugs. Eight drugs (ritonavir, daclatasvir, sofosbuvir, ribavirin, interferon alpha-2b, chloroquine, hydroxychloroquine (HCQ) and ceftriaxone had actionable pharmacogenomics (PGx) biomarkers among all ethnic groups. Fourteen drugs (ritonavir, daclatasvir, prednisone, dexamethasone, ribavirin, HCQ, ceftriaxone, zinc, interferon beta-1a, remdesivir, levofloxacin, lopinavir, human immunoglobulin G and losartan) showed significantly different pharmacogenomic characteristics in relation to the ethnic origin of the patient. Conclusion We recommend that particularly for patients with comorbidities to avoid serious DDIs, the predictive, preventive, and personalized medicine (PPPM, 3 PM) strategies have to be applied for COVID-19 treatment, and genetic tests should be performed for drugs with actionable pharmacogenes, especially in some ethnic groups with a higher frequency of functional variations, as our analysis showed. We also suggest that drugs associated with higher ethnic genetic differences should be given priority in future pharmacogenetic studies for COVID-19 management. To facilitate translation of our results into clinical practice, an approach conform with PPPM/3 PM principles was suggested. In summary, the proposed PPPM/3 PM attitude should be obligatory considered for the overall COVID-19 management.

Combined effect of nanoscale zero-valent iron and linear alkylbenzene sulfonate (LAS) to the freshwater algae Scenedesmus obliquus - Rong Cheng; Ya-ping Liu; Yi-hui Chen; Liang-jie Shen; Jiao-jiao Wu; Lei Shi; Xiang Zheng (Ecotoxicology, 2021)

3D Step-by-step inversion strategy for audio magnetotellurics data based on unstructured mesh - San Cheng; Zhi-Yong Zhang; Feng Zhou; Man Li; Hui Chen; Fu-Sheng Shi; Lin-Pin Huang; Yong Li (Applied Geophysics, 2021)

Genetic mapping reveals BjRf as a candidate gene controlling fertility restoration of the oxa CMS in Brassica juncea - Qiqi Cheng; Peijie Yao; Hui Li; Yiming Han; Kejing Xu; Shuangping Heng; Tingdong Fu; Zhengjie Wan (Theoretical and Applied Genetics, 2021)

Design of nanozymes for inflammatory bowel disease therapy - Chaoqun Cheng; Sheng Zhao; Yuan Cheng; Yufeng Liu; Hui Wei (Science China Life Sciences, 2021)

Influence of the Choice of Reference Planes on the Determination of 2D and 3D Joint Roughness Parameters - Louis Ngai Yuen Wong; Fanzhen Meng; Hui Zhou; Jin Yu; Guangtan Cheng (Rock Mechanics and Rock Engineering, 2021)

GPR40 receptor agonist TAK-875 improves cognitive deficits and reduces β-amyloid production in APPswe/PS1dE9 mice - Chao Liu; Zhao-Yan Cheng; Qing-Peng Xia; Yu-Hui Hu; Chen Wang; Ling He (Psychopharmacology, 2021)

Possible pharmaceutical applications can be developed from naturally occurring phenanthroindolizidine and phenanthroquinolizidine alkaloids - Xian-hui Jia; Huan-xin Zhao; Cheng-lin Du; Wen-zhao Tang; Xiao-jing Wang (Phytochemistry Reviews, 2021)

An in-depth analysis reveals two new genetic variants on 22q11.2 associated with vitiligo in the Chinese Han population - Xianfa Tang; Hui Cheng; Lu Cheng; Bo Liang; Mengyun Chen; Xiaodong Zheng; Fengli Xiao (Molecular Biology Reports, 2021)

Mediation Effect of Health Beliefs in the Relationship Between Health Knowledge and Uptake of Mammography in a National Breast Cancer Screening Program in Taiwan - Hui-Min Hsieh; Wei-Chieh Chang; Cheng-Ting Shen; Yi Liu; Fang-Ming Chen; Ya-Ting Kang (Journal of Cancer Education, 2021)

Experiment on the Effect of Freezing–Thawing Cyclic on Mechanical Properties of Solidified Sludge - Cheng Peng; Zongkun Tian; Hui Long; Yuqing Tan (Geotechnical and Geological Engineering, 2021)

Transcriptome analysis reveals hub genes in the hepatopancreas of Exopalaemon carinicauda in response to hypoxia and reoxygenation - Wenjun Shi; Pan Wang; Runhao Hu; Xihe Wan; Hui Shen; Hui Li; Libao Wang; Yi Qiao; Ge Jiang; Jie Cheng; Zeyu Yang (Aquaculture International, 2021)

Transcriptome analysis of differentially expressed genes in chrysanthemum MET1 RNA interference lines - Dong-ru Kang; Yi Zhu; Shuai-lei Li; Peng-hui Ai; Muhammad Ayoub Khan; Hong-xu Ding; Ying Wang; Zi-cheng Wang (Physiology and Molecular Biology of Plants, 2021)

Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson’s Disease in Chinese Population - Chun Yu Li; Ru Wei Ou; Yong Ping Chen; Xiao Jing Gu; Qian Qian Wei; Bei Cao; Ling Yu Zhang; Yan Bing Hou; Kun Cheng Liu; Xue Ping Chen; Wei Song; Bi Zhao; et al. (Molecular Neurobiology, 2021)

μ-Opioid Receptor–Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation - Hui Gao; Yuxin Zhang; Yansong Li; Haiqing Chang; Bo Cheng; Na Li; Wei Yuan; Shuang Li; Qiang Wang (Molecular Neurobiology, 2021)

Distribution, source, and ecological risk assessment of potentially toxic elements in surface sediments from Qingfeng River, Hunan, China - Zhuo Chen; Shunhong Huang; Liang Chen; Bairui Cheng; Mengfei Li; Hui Huang (Journal of Soils and Sediments, 2021)

Fusarium solani G6, a novel vitexin-producing endophytic fungus: characterization, yield improvement and osteoblastic proliferation activity - Pei-jia Tang; Zhi-hui Zhang; Li-li Niu; Cheng-bo Gu; Wen-yi Zheng; Hai-chao Cui; Xiao-han Yuan (Biotechnology Letters, 2021)

Efficacy of Probiotic Milk Formula on Blood Lipid and Intestinal Function in Mild Hypercholesterolemic Volunteers: A Placebo-control, Randomized Clinical Trial - Hui-Fang Chiu; Chia-Yuan Fang; You-Cheng Shen; Kamesh Venkatakrishnan; Chin-Kun Wang (Probiotics and Antimicrobial Proteins, 2021)

The Role of lncRNA TUG1 in the Parkinson Disease and Its Effect on Microglial Inflammatory Response - Jiang Cheng; Yangyang Duan; Fengting Zhang; Jin Shi; Hui Li; Feng Wang; Haining Li (NeuroMolecular Medicine, 2021)

Tracking the changes of wetland soil bacterial community and metabolic potentials under drought and flooding conditions in experimental microcosms - Yajun Liu; Jiajin Cheng; Xin Liu; Hui Zhong; Binhua Wang; Zhaoyu Kong; Lan Wu (Journal of Soils and Sediments, 2021)

Serum Progesterone and Testosterone Levels in Schizophrenia Patients at Different Stages of Treatment - Wei Huang; Yong-Hang Li; Shi-Qing Huang; Hui Chen; Zai-Fang Li; Xi-Xi Li; Xue-Song Li; Yong Cheng (Journal of Molecular Neuroscience, 2021)

Synergistic Effect of Moderate Steam Explosion Pretreatment and Bovine Serum Albumin Addition for Enhancing Enzymatic Hydrolysis of Poplar - Xiaodi Wang; Dayong Ding; Zhong Liu; Jinru Cheng; Xin Li; Lanfeng Hui (BioEnergy Research, 2021)

Molecular characterization of a novel single-stranded RNA virus, ChRV1, isolated from the plant-pathogenic fungus Colletotrichum higginsianum - Hong Liu; Hui Wang; Xun Lu; Cheng Xiao; Bo Peng; Qian Zhou (Archives of Virology, 2021)

Adaptive Nonsingular Fast Terminal Sliding Mode Tracking Control for an Underwater Vehicle-Manipulator System with Extended State Observer - Lijun Han; Guoyuan Tang; Maolin Cheng; Hui Huang; De Xie (Journal of Marine Science and Engineering, 2021)
An adaptive nonsingular fast terminal sliding mode control scheme with extended state observer (ESO) is proposed for the trajectory tracking of an underwater vehicle-manipulator system (UVMS), where the system is subjected to the lumped disturbances associating with both parameter uncertainties and external disturbances. The inverse kinematics for the system is obtained by the quaternion-based closed-loop inverse kinematic algorithm. The proposed controller consists of the modified nonsingular fast terminal sliding mode surface (NFTSMS) and ESO, and the adaptive control law. The utilized NFTSMS can ensure the fast convergence of the tracking errors, together with avoiding the singularity in the derivation. According to the ESO method, the estimation error of the lumped disturbance vector can realize the fixed-time convergence to the origin, along with replacing the sign function with the saturation function to attenuate the chattering. A continuous fractional PI-type robust term with adaptive laws is introduced to handle the unknown bound of the estimation error. The closed-loop system is proved to be asymptotically stable by the Lyapunov theory. Simulations are performed on a ten degree-of-freedom UVMS under four different strategies. Comparative simulation results show that the proposed controller can achieve better tracking performance and stronger robustness of the disturbance rejection.

Early Cretaceous continent basalts in the Alxa Block, NW China: geochronology, geochemistry, and tectonic implications - Jie Hui; Hongyi Cheng; Jin Zhang; Kaijun Zhang; Junfeng Qu; Beihang Zhang (International Geology Review, 2021)

A mitochondria-localized pentatricopeptide repeat protein is required to restore hau cytoplasmic male sterility in Brassica napus - Huadong Wang; Qing Xiao; Chao Wei; Hui Chen; Xiaohan Chen; Cheng Dai; Jing Wen; Chaozhi Ma; Jinxing Tu; Tingdong Fu; Jinxiong Shen; Bin Yi (Theoretical and Applied Genetics, 2021)

A female carrier of a novel DMD mutation with slightly skewed X-chromosome inactivation shows a suspected case of Becker muscular dystrophy in a Chinese family - Jianfan Chen; Hui Zheng; Zhongju Wang; Jian Wang; Fei He; Cheng Zhang; Fu Xiong (Molecular Genetics and Genomics, 2021)

Bi-allelic BRWD1 variants cause male infertility with asthenoteratozoospermia and likely primary ciliary dyskinesia - Ting Guo; Chao-Feng Tu; Dan-Hui Yang; Shui-Zi Ding; Cheng Lei; Rong-Chun Wang; Lv Liu; Xi Kang; Xiao-Qing Shen; Yi-Feng Yang; Zhi-Ping Tan; Yue-Qiu Tan; et al. (Human Genetics, 2021)

Association between prenatal phthalate exposure and gestational metabolic syndrome parameters: a systematic review of epidemiological studies - Hui Gao; Cheng Zhang; Fang-Biao Tao (Environmental Science and Pollution Research, 2021)

Inhibitory mechanism of isomerization of regular steranes in geological bodies - Qing-song Cheng; Guang-hui Huang; Min Zhang (Arabian Journal of Geosciences, 2021)

A phenological object-based approach for rice crop classification using time-series Sentinel-1 Synthetic Aperture Radar (SAR) data in Taiwan - Nguyen-Thanh Son; Chi-Farn Chen; Cheng-Ru Chen; Piero Toscano; Youg-Sing Cheng; Hong-Yuh Guo; Chien-Hui Syu (International Journal of Remote Sensing, 2021)

Building change detection in very high-resolution remote sensing image based on pseudo-orthorectification - Hui Chen; Ka Zhang; Wen Xiao; Yehua Sheng; Liang Cheng; Wei Zhou; Pengbo Wang; Dong Su; Longjie Ye; Shan Zhang (International Journal of Remote Sensing, 2021)

Gas Flow Characteristics and Optimization of Gas Drainage Borehole Layout in Protective Coal Seam Mining: A Case Study from the Shaqu Coal Mine, Shanxi Province, China - Zhiheng Cheng; Hui Pan; Quanle Zou; Zhenhua Li; Liang Chen; Jialin Cao; Kun Zhang; Yongguo Cui (Natural Resources Research, 2021)

Interplay of autophagy and cancer stem cells in hepatocellular carcinoma - Magdelyn Mei-Theng Wong; Hui-Yin Chan; Norazlin Abdul Aziz; Thamil Selvee Ramasamy; Jan-Jin Bong; Ewe Seng Ch’ng; Subasri Armon; Suat-Cheng Peh; Sin-Yeang Teow (Molecular Biology Reports, 2021)

Genetic Analysis of Prosaposin, the Lysosomal Storage Disorder Gene in Parkinson’s Disease - Yong-Ping Chen; Xiao-Jing Gu; Ru-Wei Ou; Ling-Yu Zhang; Yan-Bing Hou; Kun-Cheng Liu; Bei Cao; Qian-Qian Wei; Wei Song; Bi Zhao; Ying Wu; Jing-Qiu Cheng; et al. (Molecular Neurobiology, 2021)

Phylogeny and taxonomy of two new Alternaria (Ascomycota: Pleosporaceae) species in section Gypsophilae from China - Lin He; Hong Cheng; Aye Aye Htun; Hui Ge; Zhen Zhou Xia; Jian Wei Guo; Jian Xin Deng; Tao Du (Mycological Progress, 2021)

Detection and significance of exosomal mRNA expression profiles in the cerebrospinal fluid of patients with meningeal carcinomatosis - Peng Cheng; Feifei Feng; Hui Yang; Suqin Jin; Chao Lai; Yun Wang; Jianzhong Bi (Journal of Molecular Neuroscience, 2021)

Transgenic eukaryotic microalgae as green factories: providing new ideas for the production of biologically active substances - Qianwen Shi; Cheng Chen; Wei Zhang; Ping Wu; Meng Sun; Hui Wu; Haizhen Wu; Pengcheng Fu; Jianhua Fan (Journal of Applied Phycology, 2021)

COVID-19 illness and autoimmune diseases: recent insights - Juan Li; Hong-Hui Liu; Xiao-Dong Yin; Cheng-Cheng Li; Jing Wang (Inflammation Research, 2021)

Drug screening and development from the affinity of S protein of new coronavirus with ACE2 - Yue-Peng Jiang; Xiao-Xuan Zhao; Hui-Qing Lv; Cheng-Ping Wen (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Response of the microbial community to salt stress and its stratified effect in constructed wetlands - Xinyi Wang; Hui Zhu; Baixing Yan; Brian Shutes; Gary Bañuelos; Rui Cheng (Environmental Science and Pollution Research, 2021)

Altered asymmetries of diffusion and volumetry in basal ganglia of schizophrenia - Hui He; Cheng Luo; Ning Li; Zhiliang Li; Mingjun Duan; Gang Yao; Hongming Wang; Manxi He; Dezhong Yao (Brain Imaging and Behavior, 2021)

Mechanism of colluvial landslide induction by rainfall and slope construction: A case study - Zhou Zhou; Jun-hui Shen; Ying Li; Wei-feng Duan; Ri-chang Yang; Jun-cheng Shu; He-wei Li; Sheng-yu Tao; Sheng-zhe Zheng (Journal of Mountain Science, 2021)

New cytotoxic biflavones from Selaginella doederleinii - Li-Fei Liu; Hui-Hui Sun; Jian-Bing Tan; Qi Huang; Fei Cheng; Kang-Ping Xu; Zhen-Xing Zou; Gui-Shan Tan (Natural Product Research, 2021)

Interest-activity symptom severity predicts response to ketamine infusion in treatment-resistant depression - Mu-Hong Chen; Wei-Chen Lin; Hui-Ju Wu; Ya-Mei Bai; Cheng-Ta Li; Shih-Jen Tsai; Chen-Jee Hong; Pei-Chi Tu; Tung-Ping Su (Psychopharmacology, 2021)

Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis - Tsung-Ying Tsai; Li-Wei Lo; Shin-Huei Liu; Wen-Han Cheng; Yu-Hui Chou; Wei-Lun Lin; Yenn-Jiang Lin; Shih-Lin Chang; Yu-Feng Hu; Fa-Po Chung; Jo-Nan Liao; Tze-Fan Chao; et al. (Environmental Science and Pollution Research, 2021)

Effects of degradation succession of alpine wetland on soil organic carbon and total nitrogen in the Yellow River source zone, west China - Chun-ying Lin; Xi-lai Li; Jing Zhang; Hua-fang Sun; Juan Zhang; Hui-bang Han; Qi-hua Wang; Cheng-biao Ma; Cheng-yi Li; Yu-xing Zhang; Xue-qian Ma (Journal of Mountain Science, 2021)

Identification of Aspergillus tubingensis causing pomegranate fruit rot in China - Mei Jun Guo; Qiu Tong Wang; Yuan Hui Cheng; Cheng Lin Hou (Australasian Plant Pathology, 2021)

Carnosic acid alleviates depression-like behaviors on chronic mild stressed mice via PPAR-γ-dependent regulation of ADPN/FGF9 pathway - Xiao-qing Wang; Ya-hui Tang; Gui-rong Zeng; Li-feng Wu; Ying-jun Zhou; Ze-neng Cheng; De-Jian Jiang (Psychopharmacology, 2021)

Projections from Infralimbic Cortex to Paraventricular Thalamus Mediate Fear Extinction Retrieval - Yan Tao; Cheng-Yun Cai; Jia-Yun Xian; Xiao-Lin Kou; Yu-Hui Lin; Cheng Qin; Hai-Yin Wu; Lei Chang; Chun-Xia Luo; Dong-Ya Zhu (Neuroscience Bulletin, 2021)

NDRG2 is expressed on enteric glia and altered in conditions of inflammation and oxygen glucose deprivation/reoxygenation - Yuxin Zhang; Hui Gao; Na Li; Haiqing Chang; Bo Cheng; Yansong Li; Jiwen Miao; Shuang Li; Qiang Wang (Journal of Molecular Histology, 2021)

Effects of physical driving experience on body movement and motion sickness among passengers in a virtual vehicle - Chih-Hui Chang; Thomas A. Stoffregen; Kuangyou B. Cheng; Man Kit Lei; Chung-Chieh Li (Experimental Brain Research, 2021)

Effects of lithium resource exploitation on surface water at Jiajika mine, China - Juan-Qin Gao; Yang Yu; Deng-Hong Wang; Wei Wang; Cheng-Hui Wang; Hong-Zhang Dai; Xue-Feng Hao; Kuang Cen (Environmental Monitoring and Assessment, 2021)

Simultaneously decreased temporal variability and enhanced variability-strength coupling of emotional network connectivities are related to positive symptoms in patients with schizophrenia - Yanjia Deng; Shuguang Han; Dongliang Cheng; Hui Li; Bin Zhang; Youyong Kong; Yong Lin; Yingjia Li; Ge Wen; Kai Liu (Brain Imaging and Behavior, 2021)

A Pooled Study of Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphism in Relation to Risk, Pathology and Prognosis of Childhood Immunoglobulin A Vasculitis Nephritis - Gao Hui; Zhang Cheng; Hua Ran; Wang Ziwei; Deng Fang (Biochemical Genetics, 2021)

Allicin can suppress the activity of vascular endothelial cells probably by regulating JAK2/STAT3 pathway - Hui-Hui Sun; Xin-Min Feng; Jing-Cheng Wang; Jun Cai (Molecular and Cellular Biochemistry, 2021)

MST1 modulates Th17 activation in psoriasis via regulating TLR4-NF-κB pathway - Huayang Tang; Ze Guo; Xianfa Tang; Jinping Gao; Wenjun Wang; He Huang; Xiaodong Zheng; Hui Cheng; Yujun Sheng; Liangdan Sun (Human Cell, 2021)

High bioremediation potential of strain Chenggangzhangella methanolivorans CHL1 for soil polluted with metsulfuron-methyl or tribenuron-methyl in a pot experiment - Ting-Ting Yang; Hui-Wen Zhang; Jian Wang; Xin-Yu Li; Xu Li; Zhen-Cheng Su (Environmental Science and Pollution Research, 2021)

Constructed wetlands integrated with microbial fuel cells for COD and nitrogen removal affected by plant and circuit operation mode - Huiyang Wen; Hui Zhu; Baixing Yan; Brian Shutes; Xiangfei Yu; Rui Cheng; Xin Chen; Xinyi Wang (Environmental Science and Pollution Research, 2021)

Improving the observation and prediction capabilities for Arctic marine environment: from the perspective of Arctic Shipping - Hui Wang; Qizhen Sun; Lin Zhang; Xi Liang; Qinghua Yang; Na Liu; Chunhua Li; Qingsheng Liu; Bingrui Li; Qian Feng; Xiao Cheng; Yi Yu (Acta Oceanologica Sinica, 2021)

Two new lignans from Zanthoxylum armatum - Yan Sun; Qing-Hong Zeng; Hui-Qiang Lu; Fan-Cheng Meng; Yong Shen; Wei-You Zeng; Hao Chi; Yu-Qiang Zhou; Min Chen (Natural Product Research, 2020)

Nitrogen placement at sowing affects root growth, grain yield formation, N use efficiency in maize - Yi Cheng; Hui-Qin Wang; Peng Liu; Shu-Ting Dong; Ji-Wang Zhang; Bin Zhao; Bai-Zhao Ren (Plant and Soil, 2020)

The Hemodynamic Effect of Flow Diverter Treatment of Intracranial Bifurcation Aneurysms - Linjing Peng; Jijie Chen; Yunzhang Cheng; Nan Lv; Hui Gao; Bin Bai (Journal of Medical and Biological Engineering, 2020)

Association of in-hospital intensive statins dosage and death in arteriosclerotic cardiovascular disease with percutaneous coronary intervention: insights of multicentre cohort from China - Peng-yuan Chen; Yuan-hui Liu; Chong-yang Duan; Hua-lin Fan; Li-huan Zeng; Wei Guo; Lei Jiang; Xue-biao Wei; Wen-fei He; Sha Tao; Zhi-qiang Guo; Ji-yan Chen; et al. (European Journal of Clinical Pharmacology, 2020)

Identifying ephemeral gullies from high-resolution images and DEMs using flow-directional detection - Wen Dai; Guang-hui Hu; Xin Yang; Xian-wu Yang; Yi-han Cheng; Li-yang Xiong; Josef Strobl; Guo-an Tang (Journal of Mountain Science, 2020)

SNP of AHSA2 gene in three cattle breeds using snapshot technology - Shu-Zhu Cheng; E. Guang-Xin; Cheng-Li Liu; Wang-Dui Basang; Yan-Bin Zhu; Ri-Su Na; Yan-Guo Han; Yan Zeng; Xiao Wang; Wei-Wei Ni; Bai-Gao Yang; Xing-Hai Duan; et al. (Journal of Genetics, 2020)

Probing the fate of transplanted hematopoietic stem cells: is the combinational approach “FIT” for purpose? - Fang Dong; Hui Cheng; Hideo Ema; Tao Cheng (Science China Life Sciences, 2020)

WDR5a functions in cadmium-inhibited root meristem growth by regulating nitric oxide accumulation in Arabidopsis - Yu Zhang; Yang-Yang Tian; Lin-Feng Wang; Yun-Hui Li; Ting-Ting Li; Wen-Cheng Liu (Planta, 2020)

Predicting the spatiotemporal characteristics of flash droughts with downscaled CMIP5 models in the Jinghe River basin of China - Hui Ran; Jing Li; Zixiang Zhou; Cheng Zhang; Chengyan Tang; Yuyang Yu (Environmental Science and Pollution Research, 2020)

A novel system to rapidly detect protein–protein interactions (PPIs) based on fluorescence co-localization - Nan Hu; Zhan-Qi Dong; Ting-Ting Chen; Ning Zheng; Qin Wu; Peng Chen; Cheng Lu; Min-Hui Pan (Biotechnology Letters, 2020)

Total alkaloids from the rhizomes of Ligusticum striatum: a review of chemical analysis and pharmacological activities - Zhong-Hui Pu; Min Dai; Liang Xiong; Cheng Peng (Natural Product Research, 2020)

Two new anthraquinone derivatives and one new triarylbenzophenone analog from Selaginella tamariscina - Rui Liu; Hui Zou; Zhen-Xing Zou; Fei Cheng; Xia Yu; Ping-Sheng Xu; Xiao-Min Li; Dai Li; Kang-Ping Xu; Gui-Shan Tan (Natural Product Research, 2020)

Thermal maturation as revealed by micro-Raman spectroscopy of mineral-organic aggregation (MOA) in marine shales with high and over maturities - Xianming Xiao; Qin Zhou; Peng Cheng; Jian Sun; Dehan Liu; Hui Tian (Science China Earth Sciences, 2020)

Liquiritin inhibits proliferation and induces apoptosis in HepG2 hepatocellular carcinoma cells via the ROS-mediated MAPK/AKT/NF-κB signaling pathway - Jia-Ru Wang; Tian-Zhu Li; Cheng Wang; Shu-Mei Li; Ying-Hua Luo; Xian-Ji Piao; Yu-Chao Feng; Yi Zhang; Wan-Ting Xu; Yu Zhang; Tong Zhang; Shi-Nong Wang; et al. (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

The anti-inflammatory drug dimethyl itaconate protects against colitis-associated colorectal cancer - Qian Wang; Xin Ling Li; Yan Mei; Jia-Chong Ye; Wei Fan; Guang-Hui Cheng; Mu-Sheng Zeng; Guo-Kai Feng (Journal of Molecular Medicine, 2020)

Matriptase and prostasin proteolytic activities are differentially regulated in normal and wounded skin - Shun-Cheng Chang; Chien-Ping Chiang; Chih-Hsin Lai; Po-Wen A. Du; Yu-Sin Hung; Yu-Hsuan Chen; Hui-Yu Yang; Hao-Yu Fang; Shiao-Pieng Lee; Hung-Jen Tang; Jehng-Kang Wang; Michael D. Johnson; et al. (Human Cell, 2020)

Stable isotopes reveal effects of natural drivers and anthropogenic pressures on isotopic niches of invertebrate communities in a large subtropical river of China - Sai Wang; Lin-Hui Su; Bang-Ke Luo; Ying-Jun Qin; Simon D. Stewart; Jin-Peng Tang; Tuan-Tuan Wang; Yang Yang; Gong Cheng (Environmental Science and Pollution Research, 2020)

Characteristics of the spike and ORF3 genes of porcine epidemic diarrhea virus in Henan and Shanxi provinces of China - Jian-tao Cui; Han Qiao; Cheng-yao Hou; Hui-Hua Zheng; Xin-Sheng Li; Lan-lan Zheng; Hong-Ying Chen (Archives of Virology, 2020)

Water and salt stresses do not trigger bottom-up effects on plant-mediated indirect interactions between a leaf chewer and a sap-feeder - Yong-Cheng Dong; Zhi-Jian Wang; Rong-Yan Bu; Hui-Jie Dai; Li-Jun Zhou; Peng Han; Edwige Amiens-Desneux; Philippe Bearez; Nicolas Desneux (Journal of Pest Science, 2020)

Antibiotic resistance gene profiling in response to antibiotic usage and environmental factors in the surface water and groundwater of Honghu Lake, China - Lei Tong; Liting Qin; Chuan Guan; Mesmire Emade Wilson; Xianju Li; Dandan Cheng; Jie Ma; Hui Liu; Fujun Gong (Environmental Science and Pollution Research, 2020)

Evolution of Neolithic site distribution (9.0–4.0 ka BP) in Anhui, East China - Li Wu; Xiaoling Sun; Wei Sun; Cheng Zhu; Tongxin Zhu; Shuguang Lu; Hui Zhou; Qingchun Guo; Houchun Guan; Wei Xie; Rui Ke; Guiping Lin (Journal of Geographical Sciences, 2020)

Two new diprenylated flavanones from Derris laxiflora Benth - Hui-Chi Huang; Shih-Chang Chien; Ching-Chuan Kuo; Ming-Der Wu; Ming-Jen Cheng; Jih-Jung Chen; Hsi-Lin Chiu; Yueh-Hsiung Kuo (Natural Product Research, 2020)

Five new ent -kaurane diterpenes from Annona squamosa L. pericarps - Ya-Yun Chen; Cheng-Yao Ma; Mao-Lin Wang; Jia-Hui Lu; Peng Hu; Jian-Wei Chen; Xiang Li; Yong Chen (Natural Product Research, 2020)

Efficacy of a Smartphone Hearing Aid Simulator - Cheng-Yu Ho; Pei-Chun Li; Shuenn-Tsong Young; Ying-Hui Lai (Journal of Medical and Biological Engineering, 2020)

Distribution patterns and source identification for heavy metals in Mirs Bay of Hong Kong in China - Mei-Lin Wu; Hao Cheng; Hui Zhao; Fu-Lin Sun; Yu-Tu Wang; Jian-Ping Yin; Jiao Fei; Cui-Ci Sun; You-Shao Wang (Ecotoxicology, 2020)

Phytoplankton community, structure and succession delineated by partial least square regression in Daya Bay, South China Sea - Mei-Lin Wu; Yu-Tu Wang; Hao Cheng; Fu-lin Sun; Jiao Fei; Cui-Ci Sun; Jian-Ping Yin; Hui Zhao; You-Shao Wang (Ecotoxicology, 2020)

Reconnaissance and learning after the February 6, 2018, earthquake in Hualien, Taiwan - Jui-Liang Lin; Chun-Hsiang Kuo; Yu-Wen Chang; Shu-Hsien Chao; Yi-An Li; Wen-Cheng Shen; Chung-Han Yu; Cho-Yen Yang; Fan-Ru Lin; Hsiao-Hui Hung; Chun-Chung Chen; Chin-Kuo Su; et al. (Bulletin of Earthquake Engineering, 2020)

Effects of Nitrate Enrichment on Respiration, Photosynthesis, and Fatty Acid Composition of Reef Coral Pocillopora damicornis Larvae - Cheng-Yue Liu; Fang Zhang; You-Fang Sun; Xiao-Lei Yu; Hui Huang (Frontiers in Marine Science, 2020)

Correlation Between CCG Polymorphisms and CAG Repeats During Germline Transmission in Chinese Patients with Huntington’s Disease - Hong-Rong Cheng; Xiao-Yan Li; Hui-Li Yu; Miao Xu; Yan-Bin Zhang; Shi-Rui Gan; Hong-Lei Li; Zhi-Ying Wu (Neuroscience Bulletin, 2020)

Population Genetic Analysis for Stock Enhancement of Silver Sea Bream (Rhabdosargus sarba) in Taiwan - Te-Hua Hsu; Chang-Wen Huang; Hung-Tai Lee; Yi-Hsuan Kuo; Kwang-Ming Liu; Cheng-Hui Lin; Hong-Yi Gong (Fishes, 2020)
Stock enhancement is a method for replenishing depleted wild finfish populations by supplementing them with hatchery-raised fish. In Taiwan, silver sea bream (Rhabdosargus sarba) is a predominant commercial species involved in stock enhancement projects. Although management agencies conduct stock enhancement projects, there are a lot of private releases without records. Stock enhancement is performed by the private aquaculture sector without accurate genetic records, potentially leading to unintended consequences for wild populations. We analyzed the genetics of 459 wild and 701 hatchery-reared specimens from nine batches produced by various hatcheries. Wild and hatchery-reared samples could be considered two separate clades by using a set of stable and informative microsatellite markers including type I (from gene introns and 3′UTR) and type II markers (randomly picked up from genome). Type I microsatellite markers could more sensitively reflect the loss of genetic diversity more than type II markers in the domestication process. All specimens were considered native by using mtDNA COI and microsatellites. The genetic composition of the wild population is relatively simple, and the estimated low contribution rate of the hatchery stock (1.3–10.9%; 6–50/459) indicated a weak but significant genetic effect of stock enhancement. Therefore, establishing standards for the stock enhancement of silver sea bream for more effective supplementation of wild populations is imperative.

Long interpregnancy interval and adverse perinatal outcomes: A retrospective cohort study - Jing Lin; Han Liu; Dan-Dan Wu; Hong-Tao Hu; Hui-Hui Wang; Cheng-Liang Zhou; Xin-Mei Liu; Xiao-Jun Chen; Jian-Zhong Sheng; He-Feng Huang (Science China Life Sciences, 2020)

Review of drought impacts on carbon cycling in grassland ecosystems - Tianjie Lei; Jie Feng; Cuiying Zheng; Shuguang Li; Yang Wang; Zhitao Wu; Jingxuan Lu; Guangyuan Kan; Changliang Shao; Jinsheng Jia; Hui Cheng (Frontiers of Earth Science, 2020)

High-frequency direct shoot organogenesis from garlic (Allium sativum L.) inflorescence and clonal fidelity assessment in regenerants - Yan-Bin Wen; Xiao-Xue Liu; Hong-Jiu Liu; Cui-Nan Wu; Huan-Wen Meng; Zhi-Hui Cheng (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

The cognitive and neural mechanisms underlying norm-enforcement behaviors under social observation - Hui Ouyang; Fenfen Sun; Liping Che; Weidong Zhang; Xuemei Cheng; Li Zheng (Experimental Brain Research, 2020)

Multiple genetic factors affecting the pharmacokinetic and pharmacodynamic processes of tacrolimus in Chinese myasthenia gravis patients - Huan-Yu Meng; Xi Li; Wan-Lin Jin; Cheng-Kai Yan; Xiao-Hua Dong; Qiu Xu; Yu-Yao Peng; Zhi-Bin Li; Yi Li; Zhao-Hui Luo; Li-Qun Xu; Huan Yang (European Journal of Clinical Pharmacology, 2020)

The status of household heating in northern China: a field survey in towns and villages - Lin Zhu; Hua Liao; Bingdong Hou; Lin Cheng; Hui Li (Environmental Science and Pollution Research, 2020)

Laboratory investigation of the mechanical properties of coal-rock combined body - Zhan-bo Cheng; Liang-Hui Li; Ya-Ning Zhang (Bulletin of Engineering Geology and the Environment, 2020)

Specific Relationship between the Surface Air Temperature and the Area of the Terra Nova Bay Polynya, Antarctica - Yifan Ding; Xiao Cheng; Xichen Li; Mohammed Shokr; Jiawei Yuan; Qinghua Yang; Fengming Hui (Advances in Atmospheric Sciences, 2020)

The effects of soil phosphorus on aboveground biomass are mediated by functional diversity in a tropical cloud forest - Yikang Cheng; Hui Zhang; Runguo Zang; Xixi Wang; Wenxing Long; Xu Wang; Menghui Xiong; Robert John (Plant and Soil, 2020)

Naturally Occurring Antibodies to Tau Exists in Human Blood and Are Not Changed in Alzheimer’s Disease - Zhong-Yuan Yu; Wei-Wei Li; Hai-Mei Yang; Noralyn B. Mañucat-Tan; Jun Wang; Ye-Ran Wang; Bin-Lu Sun; Zi-Cheng Hu; Li-Li Zhang; Liang Tan; Juan Deng; Yu-Hui Liu (Neurotoxicity Research, 2020)

Brain-Wide Shape Reconstruction of a Traced Neuron Using the Convex Image Segmentation Method - Shiwei Li; Tingwei Quan; Hang Zhou; Qing Huang; Tao Guan; Yijun Chen; Cheng Xu; Hongtao Kang; Anan Li; Ling Fu; Qingming Luo; Hui Gong; et al. (Neuroinformatics, 2020)

Phytochemicals and biological activities of species from the genus Maytenus - Lei Zhang; Ming-Yue Ji; Bin Qiu; Qin-Yu Li; Ke-Yong Zhang; Ji-Cheng Liu; Lian-Sheng Dang; Min-Hui Li (Medicinal Chemistry Research, 2020)

Impacts of elevated temperature and pCO2 on the brooded larvae of Pocillopora damicornis from Luhuitou Reef, China: evidence for local acclimatization - Lei Jiang; Ming-Lan Guo; Fang Zhang; Yu-Yang Zhang; Guo-Wei Zhou; Xin-Ming Lei; Xiang-Cheng Yuan; You-Fang Sun; Tao Yuan; Lin Cai; Jian-Sheng Lian; Sheng Liu; et al. (Coral Reefs, 2020)

Human umbilical cord mesenchymal stem cell exosomes alleviate sepsis-associated acute kidney injury via regulating microRNA-146b expression - Rongxue Zhang; Yuan Zhu; Yang Li; Wanzhu Liu; Lei Yin; Siqi Yin; Cheng Ji; Yuyan Hu; Qiongni Wang; Xinru Zhou; Jingyan Chen; Wenrong Xu; et al. (Biotechnology Letters, 2020)

Ore Forming Fluids of Several Gold Deposits in the Irtysh Gold Belt, Xinjiang, China - Yingwei Wang; Jiuhua Xu; Rufu Ding; Hui Zhang; Xihui Cheng; Chunjing Bian (Journal of Earth Science, 2020)

Engineering of glycerol utilization in Pseudomonas chlororaphis GP72 for enhancing phenazine-1-carboxylic acid production - Chen Song; Sheng-Jie Yue; Wen-Hui Liu; Yi-Fan Zheng; Cheng-Hao Zhang; Tong-Tong Feng; Hong-Bo Hu; Wei Wang; Xue-Hong Zhang (World Journal of Microbiology and Biotechnology, 2020)

Ocean contributes to the melting of the Jakobshavn Glacier front - Kaijia Wang; Xiao Cheng; Zhuoqi Chen; Fengming Hui; Yan Liu; Ying Tian (Science China Earth Sciences, 2020)

Potential Genes Related to Levofloxacin Resistance in Mycobacterium tuberculosis Based on Transcriptome and Methylome Overlap Analysis - Hai-cheng Li; Hui-xin Guo; Tao Chen; Wei Wang; Zhu-hua Wu; Liang Chen; Hui-zhong Wu; Gao-po Xu; Xun-xun Chen; Lin Zhou (Journal of Molecular Evolution, 2020)
Drug-resistant Mycobacterium tuberculosis ( M. tuberculosis ) has become an increasingly serious public health problem and has complicated tuberculosis (TB) treatment. Levofloxacin (LOF) is an ideal anti-tuberculosis drug in clinical applications. However, the detailed molecular mechanisms of LOF-resistant M. tuberculosis in TB treatment have not been revealed. Our study performed transcriptome and methylome sequencing to investigate the potential biological characteristics of LOF resistance in M. tuberculosis H37Rv. In the transcriptome analysis, 953 differentially expressed genes (DEGs) were identified; 514 and 439 DEGs were significantly downregulated and upregulated in the LOF-resistant group and control group, respectively. The KEGG pathway analysis revealed that 97 pathways were enriched in this study. In the methylome analysis, 239 differentially methylated genes (DMGs) were identified; 150 and 89 DMGs were hypomethylated and hypermethylated in the LOF-resistant group and control group, respectively. The KEGG pathway analysis revealed that 74 pathways were enriched in this study. The overlap study suggested that 25 genes were obtained. It was notable that nine genes expressed downregulated mRNA and upregulated methylated levels, including pgi , fadE4 , php , cyp132 , pckA , rpmB1 , pfkB , acg , and ctpF , especially cyp132 , pckA , and pfkB , which were vital in LOF-resistant M. tuberculosis H37Rv. The overlapping genes between transcriptome and methylome could be essential for studying the molecular mechanisms of LOF-resistant M. tuberculosis H37Rv. These results may provide informative evidence for TB treatment with LOF.

Landslide mapping with remote sensing: challenges and opportunities - Cheng Zhong; Yue Liu; Peng Gao; Wenlong Chen; Hui Li; Yong Hou; Tuohuti Nuremanguli; Haijian Ma (International Journal of Remote Sensing, 2020)

Effects of telomere length on leukemogenesis - Shihui Ma; Guohuan Sun; Shangda Yang; Zhenyu Ju; Tao Cheng; Hui Cheng (Science China Life Sciences, 2020)

Spinal P2X7R contributes to streptozotocin-induced mechanical allodynia in mice - Cheng-ming Ni; He-ping Sun; Xiang Xu; Bing-yu Ling; Hui Jin; Yu-qiu Zhang; Zhi-qi Zhao; Hong Cao; Lan Xu (Journal of Zhejiang University-SCIENCE B, 2020)

CX3CR1 contributes to streptozotocin-induced mechanical allodynia in the mouse spinal cord - Cheng-ming Ni; Bing-yu Ling; Xiang Xu; He-ping Sun; Hui Jin; Yu-qiu Zhang; Hong Cao; Lan Xu (Journal of Zhejiang University-SCIENCE B, 2020)

Pulse Oximetry Monitor Feasible for Early Screening of Obstructive Sleep Apnea (OSA) - Huei-Chen Lin; Chien-Ling Su; Jun-Hui Ong; kun-ling Tsai; Yu-Wen Chen; Cheng-Yu Lin; Ling-Ling Chiang; Ching-Hsia Hung (Journal of Medical and Biological Engineering, 2020)

Methamphetamine-Induced Cognitive Deficits and Psychiatric Symptoms Are Associated with Serum Markers of Liver Damage - Tingting Zhao; Changping Zhai; Hongmei Song; Yanhai Wu; Chuanhui Ge; Yonglin Zhang; Hongxia Xu; Zhengsuo Chi; Hui Chu; Wei Shi; Xiaodong Cheng; Xin Li; et al. (Neurotoxicity Research, 2020)

Modified stepwise mini-incision microdissection testicular sperm extraction: a useful technique for patients with a history of orchidopexy affected by non-obstructive azoospermia - Peng Li; Chen-cheng Yao; Er-lei Zhi; Yuan Xu; Zhong Wan; Ying-chuan Jiang; Yu-hua Huang; Yue-hua Gong; Hui-xing Chen; Ru-hui Tian; Chao Yang; Liang-yu Zhao; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

Controlled Release of Spirotetramat Using Starch–Chitosan–Alginate-Encapsulation - Yan-Li Xie; Wayne Jiang; Fen Li; Yu Zhang; Xiao-Yu Liang; Meng Wang; Xueqing Zhou; Shao-Ying Wu; Cheng-Hui Zhang (Bulletin of Environmental Contamination and Toxicology, 2020)

Wave and current-induced dynamic response in a multilayered poroelastic seabed - Hui-Feng Qi; Zhang-Long Chen; Yi-Cheng Li; Shi-Jin Feng; Hong-Xin Chen (Bulletin of Engineering Geology and the Environment, 2020)

Population, urbanization and economic scenarios over the Belt and Road region under the Shared Socioeconomic Pathways - Cheng Jing; Hui Tao; Tong Jiang; Yanjun Wang; Jianqing Zhai; Lige Cao; Buda Su (Journal of Geographical Sciences, 2020)

Feasibility of growing halophyte “agretti” (Salsola soda) as an alternative boron-tolerant food crop in unproductive boron-laden regions - Hui Zhu; Rui Cheng; Gary Bañuelos; Tiziana Centofanti (Plant and Soil, 2019)

Expressional and Functional Verification of the Involvement of CmEXPA4 in Chrysanthemum Root Development - Hong Ren; Li-zhu Wen; Yun-hui Guo; Yuan-yuan Yu; Cui-hui Sun; Hong-mei Fan; Fang-fang Ma; Cheng-shu Zheng (Journal of Plant Growth Regulation, 2019)

Composition and change in the microbiome of Diaphorina citri infected with Candidatus Liberibacter asiaticus in China - Xiao-bing Song; Ai-tian Peng; Jin-feng Ling; Yi-ping Cui; Bao-ping Cheng; Lian-hui Zhang (International Journal of Tropical Insect Science, 2019)

Chronology of coastal aeolian deposition and its paleoenvironmental implications on the Liuao Peninsula of South China - Jian-hui Jin; Zhi-zhong Li; Zhi-yong Ling; Fei Zheng; Xiao-lin Xu; Yan Cheng; Xiang-dong Cao; Zhi-xing Li; Wen-jing Zhang; Yong-qing Ren (Journal of Mountain Science, 2019)

The effect of quorum sensing on performance of salt-tolerance aerobic granular sludge: linking extracellular polymeric substances and microbial community - Cheng Li; Wei Li; Hui Li; Meng Hou; Xiao Wu; Jin-long Zhuang; Yong-di Liu (Biodegradation, 2019)

Application of Cas12a and nCas9-activation-induced cytidine deaminase for genome editing and as a non-sexual strategy to generate homozygous/multiplex edited plants in the allotetraploid genome of tobacco - Chen-Tran Hsu; Yu-Jung Cheng; Yu-Hsua Yuan; Wei-Fon Hung; Qiao-Wei Cheng; Fu-Hui Wu; Lan-Ying Lee; Stanton B. Gelvin; Choun-Sea Lin (Plant Molecular Biology, 2019)

Preliminary study on the dynamics of heavy metals in saline wastewater treated in constructed wetland mesocosms or microcosms filled with porous slag - Yinxiu Liang; Hui Zhu; Gary Bañuelos; Yingying Xu; Baixing Yan; Xianwei Cheng (Environmental Science and Pollution Research, 2019)

Synthesis of natural product inulavosin via Ga(OTf) 3 -Catalyzed Hetero Diels–Alder Dimerization of salicyl alcohol derivative - Pi-Xian Gong; Hui-Jing Li; Meirong Wang; Yun-Fei Cheng; Yan-Chao Wu (Natural Product Research, 2019)

Correction to: SPECT/CT imaging of apoptosis in aortic aneurysm with radiolabeled duramycin - Chengkai Hu; Hui Tan; Qingyu Lin; Mieradilijiang Abudupataer; Yun Zhao; Jun Li; Jiawei Gu; Dengfeng Cheng; Chunsheng Wang; Kai Zhu; Hao Lai (Apoptosis, 2019)

An indole diterpenoid isolated from the fungus Drechmeria sp. and its antimicrobial activity - Jia-Hao Liang; Xiao-Kui Huo; Zhong-Bin Cheng; Cheng-Peng Sun; Jian-Chao Zhao; Xiao-Hui Kang; Tian-Yuan Zhang; Zhong-Jian Chen; Tian-Mei Yang; Ying-Ying Wu; Xiao-Peng Deng; Yi-Xuan Zhang (Natural Product Research, 2019)

Mapping oil palm plantation expansion in Malaysia over the past decade (2007–2016) using ALOS-1/2 PALSAR-1/2 data - Yuqi Cheng; Le Yu; Yidi Xu; Hui Lu; Arthur P. Cracknell; Kasturi Kanniah; Peng Gong (International Journal of Remote Sensing, 2019)

From Analysis of Ischemic Mouse Brain Proteome to Identification of Human Serum Clusterin as a Potential Biomarker for Severity of Acute Ischemic Stroke - Hailong Song; Hui Zhou; Zhe Qu; Jie Hou; Weilong Chen; Weiwu Cai; Qiong Cheng; Dennis Y. Chuang; Shanyan Chen; Shuwei Li; Jilong Li; Jianlin Cheng; et al. (Translational Stroke Research, 2019)

Development of a Direction-Oriented Motion and Short-Sitting and Lying Tai Chi (DOM-SSLTC) Model for Function Recovery in Stroke Patients - Lian-Hui Lee; Hwai-Ting Lin; Nai-Wen Tsai; Yung-Chieh Yen; Cheng-Hsien Lu; Chun-Chung Lui; Hsien-Ming Chung; Kun-Chang Tsai; Shih-Pin Hsu; Huan-Wen Tsui (Journal of Medical and Biological Engineering, 2019)

The mechanism of damage in the midgut of Bombyx mori after chlorantraniliprole exposure - Jiahuan Hu; Mengxue Li; Zhengting Lu; Tingting Mao; Jian Chen; Hui Wang; Jianwei Qu; Yilong Fang; Xiaoyu Cheng; Jinxin Li; Fanchi Li; Bing Li (Ecotoxicology, 2019)

Influence of High Relative Humidity on Secondary Organic Carbon: Observations at a Background Site in East China - Linlin Liang; Guenter Engling; Yuan Cheng; Xiaoye Zhang; Junying Sun; Wanyun Xu; Chang Liu; Gen Zhang; Hui Xu; Xuyan Liu; Qianli Ma (Journal of Meteorological Research, 2019)