Not out of the woods yet: Signatures of the prolonged negative genetic consequences of a population bottleneck in a rapidly re‐expanding wader, the black‐faced spoonbill Platalea minor - Shou‐Hsien Li; Yang Liu; Chia‐Fen Yeh; Yuchen Fu; Carol K. L. Yeung; Chun‐Cheng Lee; Chi‐Cheng Chiu; Tung Hui Kuo; Fang‐Tse Chan; Yu‐Chia Chen; Wen‐Ya Ko; Cheng‐Te Yao (Molecular Ecology, 2022)
The long‐term persistence of a population which has suffered a bottleneck partly depends on how historical demographic dynamics impacted its genetic diversity and the accumulation of deleterious mutations. Here we provide genomic evidence for the genetic effect of a recent population bottleneck in the endangered black‐faced spoonbill ( Platalea minor ) after its rapid population recovery. Our data suggest that the bird's effective population size, N e , had been relatively stable (7500–9000) since 22,000 years ago; however, a recent brief yet severe bottleneck ( N e = 20) which we here estimated to occur around the 1940s wiped out >99% of its historical N e in roughly three generations. Despite a >15‐fold population recovery since 1988, we found that black‐faced spoonbill population has higher levels of inbreeding (7.4 times more runs of homozygosity) than its sister species, the royal spoonbill ( P. regia ), which is not thought to have undergone a marked population contraction. Although the two spoonbills have similar levels of genome‐wide genetic diversity, our results suggest that selection on more genes was relaxed in the black‐faced spoonbill; moreover individual black‐faced spoonbills carry more putatively deleterious mutations (Grantham's score > 50), and may therefore express more deleterious phenotypic effects than royal spoonbills. Here we demonstrate the value of using genomic indices to monitor levels of genetic erosion, inbreeding and mutation load in species with conservation concerns. To mitigate the prolonged negative genetic effect of a population bottleneck, we recommend that all possible measures should be employed to maintain population growth of a threatened species.

Biogeography of culturable marine bacteria from both poles reveals that ‘everything is not everywhere’ at the genomic level - Qi‐Long Qin; Zhi‐Bin Wang; Qian‐Qian Cha; Sha‐Sha Liu; Xue‐Bing Ren; Hui‐Hui Fu; Mei‐Ling Sun; Dian‐Li Zhao; Andrew McMinn; Yin Chen; Xiu‐Lan Chen; Yu‐Zhong Zhang; et al. (Environmental Microbiology, 2022)
Summary Based on 16S rRNA gene analyses, the same bacterial operational taxonomic units (OTUs) are common to both the Arctic and Antarctic oceans, supporting the concept ‘everything is everywhere’. However, whether the same OTUs from both poles have identical genomes, i.e. whether ‘everything is still everywhere’ at the genomic level has not yet been examined systematically. Here, we isolated, sequenced and compared the genomes of 45 culturable marine bacteria belonging to three genera of Salinibacterium , Psychrobacter and Pseudoalteromonas from both polar oceans. The bacterial strains with identical 16S rRNA genes were common to both poles in every genus, and four identical genomes were detected in the genus Salinibacterium from the Arctic region. However, no identical genomes were observed from opposite poles in this study. Our data, therefore, suggest that ‘everything is not everywhere’ at the genomic level. The divergence time between bacteria is hypothesized to exert a strong impact on the bacterial biogeography at the genomic level. The geographical isolation between poles was observed for recently diverged, highly similar genomes, but not for moderately similar genomes. This study thus improves our understanding of the factors affecting the genomic‐level biogeography of marine microorganisms isolated from distant locations.

Adsorption of BDE-209 to Polyethylene Microplastics: Effect of Microplastics Property and Metal Ions - Yanfeng Zhu; Xiaoxiao Li; Liping Wang; Nan Hui; Jing Ma; Fu Chen (Water, Air, & Soil Pollution, 2021)

Recent advances in tissue stem cells - Xin Fu; Qiang He; Yu Tao; Mengdi Wang; Wei Wang; Yalong Wang; Qing Cissy Yu; Fang Zhang; Xiaoyu Zhang; Ye-Guang Chen; Dong Gao; Ping Hu; et al. (Science China Life Sciences, 2021)

The xyloglucan galactosylation modulates the cell wall stability of pollen tube - Qiqi Wei; Ying Yang; Hui Li; Zhiwen Liu; Rong Fu; Hanqian Feng; Chao Li (Planta, 2021)

Identification of key gene networks controlling vernalization development characteristics of Isatis indigotica by full-length transcriptomes and gene expression profiles - Pan Wang; Dong Liu; Fu-Hong Yang; Hui Ge; Xin Zhao; Hong-Gang Chen; Tao Du (Physiology and Molecular Biology of Plants, 2021)
Isatis indigotica Fort . , as a common Chinese medicinal raw material, will lose its medicinal value if it blooms early, so it is highly valuable to clarify the induction mechanism of the vernalization of I. indigotica at low temperature. In this study, the concentrations of soluble sugar, proline, glutathione and zeatin in two germplasms of I. indigotica with different degrees of low temperature tolerance (Y1 and Y2) were determined at 10 days, 20 days and 30 days of low-temperature treatment, and the full-length transcriptome of 24 samples was sequenced by Nanopore sequencing with Oxford Nanopore Technologies (ONT). After that, the data of transcripts involved in the vernalization of I. indigotica at low temperature were obtained, and these transcripts were identified using weighted gene co-expression network analysis (WGCNA). The results revealed the massive accumulation of soluble sugar and proline in Y1 and Y2 after low temperature induction. A total of 18,385 new transcripts, 6168 transcription factors and 470 lncRNAs were obtained. Differential expression analysis showed that gibberellin, flavonoids, fatty acids and some processes related to low temperature response were significantly enriched. Eight key transcripts were identified by WGCNA, among which ONT.14640.1, ONT.9119.1, ONT.13080.2 and ONT.16007.1 encodes a flavonoid transporter, 9-cis-epoxycarotenoid dioxygenase 3 (NCED3), growth factor gene and L-aspartate oxidase in plants, respectively . It indicated that secondary metabolites such as hormones and flavonoids play an important role in the vernalization of I. indigotica . qRT-PCR proved the reliability of transcriptome results. These results provide important insights on the low-temperature vernalization of I. indigotica , and provide a research basis for analyzing the vernalization mechanism of I. indigotica .

Two new species of Chalciporus (Boletaceae, Boletales) from tropical China - Chang Xu; Zhi-Qun Liang; Hui-Jing Xie; Shuai Jiang; Xin-Hua Fu; Nian-Kai Zeng (Mycological Progress, 2021)

Occurrence, source apportionment, and carcinogenic risk assessment of polycyclic aromatic hydrocarbons in urban road dusts in Shanghai - Xue-Tong Wang; Rui Fu; Ying Zhou; Cheng-Lin Wang; Guo-Fa Ren; Xiao-Li Wang; Hui Li (Environmental Science and Pollution Research, 2021)

Investigation on the statistical characteristics of geoelectric field seismic anomalies in the North–South seismic belt of Chinese mainland - Hou Ze-Yu; An Zhang-Hui; Fan Ying-Ying; Tan Da-Cheng; Fu A-Long; Wei Lei (Acta Geophysica, 2021)

Three new dimeric 2-(2-phenylethyl)chromones from artificial agarwood of Aquilaria sinensis - Pan Xiang; Wen-Hua Dong; Cai-Hong Cai; Wei Li; Li-Man Zhou; Hao-Fu Dai; Hui-Qin Chen; Wen-Li Mei (Natural Product Research, 2021)

Long-term partial substitution of chemical fertilizer with green manure regulated organic matter mineralization in paddy soil dominantly by modulating organic carbon quality - Peidong Xu; Ji Wu; Hui Wang; Shang Han; Jun Zhu; Qingling Fu; Mingjian Geng; Hongqing Hu; Qiaoyun Huang (Plant and Soil, 2021)

Transcriptome analysis reveals differing response and tolerance mechanism of EPSPS and GAT genes among transgenic soybeans - Bing-Fu Guo; Hui-Long Hong; Li-Ping Sun; Yong Guo; Li-Juan Qiu (Molecular Biology Reports, 2021)

miR-106b-5p upregulation is associated with microglial activation and inflammation in the mouse hippocampus following status epilepticus - Tao Yu; Hui Fu; Jing-Jing Sun; Dan-Rui Ding; Hua Wang (Experimental Brain Research, 2021)

Selection for low-cadmium cultivars and cadmium subcellular distribution comparison between two selected cultivars of eggplant (Solanum melongena L.) - Chuang Shen; Hui-Ling Fu; Qiong Liao; Bai-Fei Huang; Ying-Ying Huang; Jun-Liang Xin (Environmental Science and Pollution Research, 2021)

Hydrological characteristics and changes in the Nu-Salween River basin revealed with model-based reconstructed data - Fan Yang; Hui Lu; Kun Yang; Guang-wei Huang; Yi-shan Li; Wei Wang; Ping Lu; Fu-qiang Tian; Yu-gang Huang (Journal of Mountain Science, 2021)

Effects of fasting on collective movement and fission–fusion dynamics in both homogeneous and heterogeneous shoals of a group‐living cyprinid fish species - Yu‐Hui Zheng; Shi‐Jian Fu (Journal of Fish Biology, 2021)
The present study aimed to reveal the effect of fasting (21 days) on collective movement and interaction dynamics in both homogeneous (eight members fed a commercial diet or deprived of food) and heterogeneous (four fed + four starved members) shoals of juvenile qingbo ( Spinibarbus sinensis ). The authors of this study measured the shoaling behaviour in both a commonly used rectangular open arena with no spatial complexity and a radial arm maze. When measured in the open arena, the starved shoals had a faster swimming speed and acceleration rate and a longer interindividual distance than the fed shoals, possibly because of the elevated foraging motivation. Nonetheless, the values of the heterogeneous groups were similar to those of the fed groups. Furthermore, in contrast to the fish in homogeneous shoals, the starved fish in heterogeneous shoals showed a slower acceleration rate and speed than fed members in heterogeneous shoals. These results, combined with the relationships of variables at the among‐ and within‐shoal levels, suggested that starved fish limited their motion in heterogeneous shoals to maintain group cohesion but that the fed fish contributed more to maintaining shoal structure, possibly because of the higher energy expenditure required for movement changes. When monitored in a radial arm maze, starved shoals showed more fission–fusion episodes without sacrificing group cohesion, as they adaptively adjusted the frequency and duration of each majority choice. The among‐shoal variation revealed that the heterogeneous groups showed less variation in the open arena but more variation in the radius maze than did the homogeneous groups. This difference might arise because dominant members have opposite effects on shoal behaviour and consensus decisions. In conclusion, the present study showed opposite effects of feeding states on collective behaviour between homogeneous and heterogeneous shoals, possibly because of the complicated interactions among members with different energy storage levels and foraging motivations. Furthermore, the heterogeneous groups showed a difference between shoal behaviour in the open area and exploration in the radial arm maze. Future studies manipulating the personality composition of starved and fed members of heterogeneous groups might yield interesting results.

New types of ATP ‐grasp ligase are associated with the novel pathway for complicated mycosporine‐like amino acid production in desiccation‐tolerant cyanobacteria - Zhong‐Chun Zhang; Kai Wang; Fu‐Hua Hao; Jin‐Long Shang; Hui‐Ru Tang; Bao‐Sheng Qiu (Environmental Microbiology, 2021)
Summary Mycosporine‐like amino acids (MAAs) were widespread in diverse organisms to attenuate UV radiation. We recently characterized the large, complicated MAA mycosporine‐2‐(4‐deoxygadusolyl‐ornithine) in desert cyanobacterium Nostoc flagelliforme . Synthesis of this MAA requires the five‐gene cluster mysABDC2C3 . Here, bioinformatic analysis indicated that mysC duplication within five‐gene mys clusters is strictly limited to drought‐tolerant cyanobacteria. Phylogenic analysis distinguished these duplicated MysCs into two clades that separated from canonical MysCs. Heterologous expression of N. flagelliforme mys genes in Escherichia coli showed that MysAB produces 4‐deoxygadusol. The ATP‐grasp ligase of MysC3 catalyses the linkage of the δ‐ or ε‐amino group of ornithine/lysine to 4‐deoxygadusol, yielding mycosporine‐ornithine or mycosporine‐lysine respectively. The ATP‐grasp ligase of MysC2 strictly condenses the α‐amino group of mycosporine‐ornithine to another 4‐deoxygadusol. MysD (D‐Ala–D‐Ala ligase) functions following MysC2 to catalyse the formation of mycosporine‐2‐(4‐deoxygadusolyl‐ornithine). High arginine content likely provides a greater pool of ornithine over other amino acids during rehydration of desiccated N. flagelliforme . Duplication of ATP‐grasp ligases is specific for the use of substrates that have two amino groups (such as ornithine) for the production of complicated MAAs with multiple chromophores. This five‐enzyme biosynthesis pathway for complicated MAAs is a novel adaptation of cyanobacteria for UV tolerance in drought environments.

A new ergostane derivative from the leaves of Heynea trijuga Roxburgh - Shou-Bai Liu; Zheng Cui; Hui-Qin Chen; Hao Wang; Wen-Hua Dong; Cai-Hong Cai; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2021)

A review of the botany, traditional uses, phytochemistry and pharmacology of Nepeta tenuifolia Briq. - Mingqiu Shan; Yulan Jiang; Yuanyuan Fu; Yongyi Zhou; Zhihui Lu; Sheng Yu; Hui Yan; Chanchan Liu; Peidong Chen; Beihua Bao; Li Zhang; Qinan Wu (Phytochemistry Reviews, 2021)

An Investigation of Toxic Metal Levels (Pb, Cd, Cr, As, Hg) in Dried Porphyra and Laminaria Collected from Coastal Cities, China - Yan Chen; Yong-tao Liu; Fu-hua Wang; Dian Wen; Hui Yang; Xiao-li Zhao (Biological Trace Element Research, 2021)

Landslide mapping and analysis along the China-Pakistan Karakoram Highway based on SBAS-InSAR detection in 2017 - Xiao-jun Su; Yi Zhang; Xing-min Meng; Dong-xia Yue; Jin-hui Ma; Fu-yun Guo; Zi-qiang Zhou; Mohib Ur Rehman; Zainab Khalid; Guan Chen; Run-qiang Zeng; Fu-meng Zhao (Journal of Mountain Science, 2021)

Characteristics and drivers of daily nitrogen and phosphorus losses from rice-rapeseed rotation systems in the middle reaches of the Yangtze River - Yali Wu; Jin Fu; Xiaoqi Kang; Xiaoying Zhan; Yuan Niu; Hui Yu (Environmental Science and Pollution Research, 2021)

Protective effect of Bombyx mori gloverin on intestinal epithelial cells exposure to enterotoxigenic E. coli - Qian Lin; Qingqing Fu; Guoqi Su; Daiwen Chen; Bing Yu; Yuheng Luo; Ping Zheng; Xiangbing Mao; Zhiqing Huang; Jie Yu; Junqiu Luo; Hui Yan; et al. (Brazilian Journal of Microbiology, 2021)

3D Step-by-step inversion strategy for audio magnetotellurics data based on unstructured mesh - San Cheng; Zhi-Yong Zhang; Feng Zhou; Man Li; Hui Chen; Fu-Sheng Shi; Lin-Pin Huang; Yong Li (Applied Geophysics, 2021)

Genetic mapping reveals BjRf as a candidate gene controlling fertility restoration of the oxa CMS in Brassica juncea - Qiqi Cheng; Peijie Yao; Hui Li; Yiming Han; Kejing Xu; Shuangping Heng; Tingdong Fu; Zhengjie Wan (Theoretical and Applied Genetics, 2021)

Three Paralogous R2R3-MYB Genes Contribute to Delphinidin-Related Anthocyanins Synthesis in Petunia hybrida - Zhenzhu Fu; Hui Jiang; Yacong Chao; Xiaoyu Dong; Xin Yuan; Limin Wang; Jing Zhang; Menglan Xu; Huijuan Wang; Yanmin Li; Jie Gao; Hechen Zhang (Journal of Plant Growth Regulation, 2021)

Resource status and protection strategies of mangroves in China - Xiu-Mei Fu; Hui-Ying Tang; Yang Liu; Meng-Qi Zhang; Shan-Shan Jiang; Fang Yang; Xiao-Yan Li; Chang-Yun Wang (Journal of Coastal Conservation, 2021)
Mangrove is a typical natural landscape with great ecological, social and economic functions and values, and should be highly valued and protected. However, in the past few decades, mangrove resources have suffered serious damage, and there are also many deficiencies in mangrove protection. Chinese mangroves, as an important part of the global mangroves, are of great research value. In the present study, the status and historical dynamic process of Chinese mangrove resources were investigated and discussed to illustrate the problems of resources from three aspects, including mangrove distribution, area and plant species. Based on field research, literature research and data analysis, it was revealed that Chinese mangroves are distributed in eight provinces and regions along the southeast coast with an area of 35,749.25 hm 2 , 38 species and 40 nature reserves. The protection situation and deficiencies were analyzed from the establishment and management of nature reserves. Based on the resource status and problems, reasonable strategies were proposed to protect and manage mangroves mainly from four aspects, including publicity and education, resources restoration and protection technology, legal system establishment, and comprehensive protection and management.

Porcine circovirus type 2 (PCV2) infection in Hebei Province from 2016 to 2019: a retrospective study - Lei Han; Guang-fu Yuan; Shao-jie Chen; Fei Dai; Lin-shan Hou; Jing-hui Fan; Yu-zhu Zuo (Archives of Virology, 2021)

Three new 5,6,7,8-tetrahydro-2-(2-phenylethyl)chromones and one new dimeric 2-(2-phenylethyl)chromone from agarwood of Aquilaria crassna Pierre ex Lecomte in Laos - Yang-Mei Zhao; Li Yang; Fan-Dong Kong; Wen-Hua Dong; Wei Li; Hui-Qin Chen; Hao Wang; Cai-Hong Cai; Cui-Juan Gai; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2021)

Bisphenol A induces ovarian cancer cell proliferation and metastasis through estrogen receptor-α pathways - Chen Sang; Yu Song; Tong-wang Jin; Shuo Zhang; Linyan Fu; Yi Zhao; Xinxin Zou; Zhe Wang; Hui Gao; Sijin Liu (Environmental Science and Pollution Research, 2021)

Deformation of the Zhangjiazhuang high-speed railway tunnel: an analysis of causal mechanisms using geomorphological surveys and D-InSAR monitoring - Xing-min Meng; Tian-jun Qi; Yan Zhao; Tom Dijkstra; Wei Shi; Yin-fei Luo; Yuan-zhao Wu; Xiao-jun Su; Fu-meng Zhao; Jin-hui Ma; Yi Zhang; Guan Chen; et al. (Journal of Mountain Science, 2021)

Kynurenine pathway as alternative biosynthetic pathway for fusaric acid in Fusarium oxysporum f.sp. cubense - Tao Zeng; Hui-Cai Zeng; Mei-Ying Fu; Kai-Kun Huang; Jian-Chun Guo; Xin-Wen Hu (Australasian Plant Pathology, 2021)

Ensemble machine learning to evaluate the in vivo acute oral toxicity and in vitro human acetylcholinesterase inhibitory activity of organophosphates - Liangliang Wang; Junjie Ding; Peichang Shi; Li Fu; Li Pan; Jiahao Tian; Dongsheng Cao; Hui Jiang; Xiaoqin Ding (Archives of Toxicology, 2021)

Cysteiniphilum marinum sp. nov., isolated from coastal seawater - Hai-Min Luo; Jun-Hui Feng; Liang-Hui Li; Meng-Meng Li; Ru-Qin Liu; Fu Chen; Ying Lin; Wen-Jun Li; Ping-Hua Qu; Min Xiao (Antonie van Leeuwenhoek, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Neuroprotective carbazole alkaloids from the stems and leaves of Clausena lenis - Gui Yan; Yu-Jie Li; Ying-Ying Zhao; Jia-Ming Guo; Wen-Hao Zhang; Ming-Ming Zhang; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2021)

Does consciousness overflow cognitive access? Novel insights from the new phenomenon of attribute amnesia - Yingtao Fu; Wenchen Yan; Mowei Shen; Hui Chen (Science China Life Sciences, 2021)

An Enhanced Virtual Crack Closure Technique for Stress Intensity Factor Calculation along Arbitrary Crack Fronts and the Application in Hydraulic Fracturing Simulation - Hui Wu; Randolph R. Settgast; Pengcheng Fu; Joseph P. Morris (Rock Mechanics and Rock Engineering, 2021)

Sleep Characteristics and Cerebrospinal Fluid Progranulin in Older Adults: The CABLE Study - Meng Wang; Fu-Rong Sun; Yan-Lin Bi; Ya-Hui Ma; Jian-Jun Yin; Xue-Ning Shen; Xiao-Tong Wang; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2021)

Dehydroabietic acid improves nonalcoholic fatty liver disease through activating the Keap1/Nrf2-ARE signaling pathway to reduce ferroptosis - Gai Gao; Zhishen Xie; Er-wen Li; Yong Yuan; Yu Fu; Pan Wang; Xiaowei Zhang; Yonghui Qiao; Jiangyan Xu; Christian Hölscher; Hui Wang; Zhenqiang Zhang (Journal of Natural Medicines, 2021)

Patterns of Seasonal Stability of Lake Phytoplankton Mediated by Resource and Grazer Control During Two Decades of Re-oligotrophication - Hui Fu; Guixiang Yuan; Korhan Özkan; Liselotter Sander Johansson; Martin Søndergaard; Torben L. Lauridsen; Erik Jeppesen (Ecosystems, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

A mitochondria-localized pentatricopeptide repeat protein is required to restore hau cytoplasmic male sterility in Brassica napus - Huadong Wang; Qing Xiao; Chao Wei; Hui Chen; Xiaohan Chen; Cheng Dai; Jing Wen; Chaozhi Ma; Jinxing Tu; Tingdong Fu; Jinxiong Shen; Bin Yi (Theoretical and Applied Genetics, 2021)

Spatial prediction of soil calcium carbonate content based on Bayesian maximum entropy using environmental variables - Mei Shan; Shuang Liang; Hongchen Fu; Xiaoli Li; Yu Teng; Jingwen Zhao; Yaxin Liu; Chen Cui; Li Chen; Hai Yu; Shunbang Yu; Yanling Sun; et al. (Nutrient Cycling in Agroecosystems, 2021)

A female carrier of a novel DMD mutation with slightly skewed X-chromosome inactivation shows a suspected case of Becker muscular dystrophy in a Chinese family - Jianfan Chen; Hui Zheng; Zhongju Wang; Jian Wang; Fei He; Cheng Zhang; Fu Xiong (Molecular Genetics and Genomics, 2021)

Delineating the organization of projection neuron subsets in primary visual cortex with multiple fluorescent rabies virus tracing - Liang Li; Yajie Tang; Leqiang Sun; Jinsong Yu; Siheng Zhang; Hui Gong; Hannah C. Webber; Xiaoyu Zhang; Zhe Hu; Xiangning Li; Khaista Rahman; Xiangwei Shi; et al. (Brain Structure and Function, 2021)

Ship Roll Prediction Algorithm Based on Bi-LSTM-TPA Combined Model - Yuchao Wang; Hui Wang; Dexin Zou; Huixuan Fu (Journal of Marine Science and Engineering, 2021)
When ships sail on the sea, the changes of ship motion attitude presents the characteristics of nonlinearity and high randomness. Aiming at the problem of low accuracy of ship roll angle prediction by traditional prediction algorithms and single neural network model, a ship roll angle prediction method based on bidirectional long short-term memory network (Bi-LSTM) and temporal pattern attention mechanism (TPA) combined deep learning model is proposed. Bidirectional long short-term memory network extracts time features from the forward and reverse of the ship roll angle time series, and temporal pattern attention mechanism extracts the time patterns from the deep features of a bidirectional long short-term memory network output state that are beneficial to ship roll angle prediction, ignore other features that contribute less to the prediction. The experimental results of real ship data show that the proposed Bi-LSTM-TPA combined model has a significant reduction in MAPE, MAE, and MSE compared with the LSTM model and the SVM model, which verifies the effectiveness of the proposed algorithm.

Human β-Defensin 118 Attenuates Escherichia coli K88–Induced Inflammation and Intestinal Injury in Mice - Qian Lin; Qingqing Fu; Xiang Li; Yuheng Luo; Junqiu Luo; Daiwen Chen; Xiangbing Mao; Bing Yu; Ping Zheng; Zhiqing Huang; Jie Yu; Hui Yan; et al. (Probiotics and Antimicrobial Proteins, 2021)

Transgenic eukaryotic microalgae as green factories: providing new ideas for the production of biologically active substances - Qianwen Shi; Cheng Chen; Wei Zhang; Ping Wu; Meng Sun; Hui Wu; Haizhen Wu; Pengcheng Fu; Jianhua Fan (Journal of Applied Phycology, 2021)

miR-23b Attenuates LPS-Induced Inflammatory Responses in Acute Lung Injury via Inhibition of HDAC2 - Zhi-Feng Luo; Xiang-Hui Jiang; Huan Liu; Li-Yuan He; Xiong Luo; Fu-Chun Chen; Yu-Lin Tan (Biochemical Genetics, 2021)

Spatio-temporal precipitation changes and their localized predictors in the Taihang Mountain region, North China - Tonggang Fu; Hui Gao; Hongzhu Liang; Jintong Liu (Stochastic Environmental Research and Risk Assessment, 2021)

Syndecan-3 contributes to the regulation of the microenvironment at the node of Ranvier following end-to‑side neurorrhaphy: sodium image analysis - Chiung-Hui Liu; Yu-Chen Kuo; Che-Yu Wang; Chao-Chun Hsu; Ying-Jui Ho; Yun-Chi Chiang; Fu-Der Mai; Wei-Jhih Lin; Wen-Chieh Liao (Histochemistry and Cell Biology, 2021)

Spatial variability of the molecular composition of humic acids from subtropical forest soils - Li Jiang; Jun Zhu; Hui Wang; Qingling Fu; Hongqing Hu; Qiaoyun Huang (Journal of Soils and Sediments, 2021)

Effect of clonal fragmentation on the growth of Vallisneria natans (Lour.) Hara at contrasting nutrient and light conditions - Hui Peng; Dabing Ge; Guixiang Yuan; Dongsheng Zou; Hui Fu; Erik Jeppesen (Hydrobiologia, 2021)

Phenotypic characteristics of ramie (Boehmeria nivea L) germplasm resources based on UAV remote sensing - Dandan Cui; Guoxian Cui; Ruifang Yang; Wei She; Yaoduan Liu; Hui Wang; Xiaohui Su; Jilong Wang; Wanhui Liu; Xinhui Wang; Jieyi Liu; Hongyu Fu (Genetic Resources and Crop Evolution, 2021)

Brainstem atrophy in the early stage of Alzheimer’s disease: a voxel-based morphometry study - Xiaoxi Ji; Hui Wang; Minwei Zhu; Yingjie He; Hong Zhang; Xiaoguang Chen; Wenpeng Gao; Yili Fu (Brain Imaging and Behavior, 2021)

Experimental evidence for long‐term coexistence of copiotrophic and oligotrophic bacteria in pelagic surface seawater - Yi Li; Zhi‐Bin Wang; Xi‐Ying Zhang; Yan‐Ru Dang; Lin‐Lin Sun; Wei‐Peng Zhang; Hui‐Hui Fu; Gui‐Peng Yang; Min Wang; Andrew McMinn; Xiu‐Lan Chen; Yin Chen; et al. (Environmental Microbiology, 2021)
Summary Most marine copiotrophic bacteria can produce extracellular enzymes to degrade biopolymers into bio‐available smaller solutes, while oligotrophic bacteria usually cannot. Bacterial extracellular enzymes and enzymatic products can be a common resource that could be utilized by both copiotrophs and oligotrophs; when present, oligotrophs may outcompete the enzyme‐producing copiotrophs. However, copiotrophs and oligotrophs consistently coexist in the ocean. How they maintain coexistence has still not been experimentally studied. In this study, the interaction and coexistence of a copiotroph and an oligotroph, isolated from the same surface seawater sample and utilizing the same proteinaceous substrate, were experimentally investigated. The copiotroph could secrete extracellular proteases to degrade and then utilize the proteinaceous substrate. The oligotroph was unable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino acids. The copiotroph outcompeted the oligotroph by adsorbing the amino acids quickly and having a higher growth rate in the rich medium. The oligotroph survived by adapting to low concentration of nutrients. The copiotroph and oligotroph were able to maintain long‐term (up to 142 days) coexistence in the laboratory. This study indicates that differences in the utilization of different concentrations of nutrients can drive the coexistence of marine copiotrophs and oligotrophs.

Modes of genetic adaptations underlying functional innovations in the rumen - Xiangyu Pan; Yudong Cai; Zongjun Li; Xianqing Chen; Rasmus Heller; Nini Wang; Yu Wang; Chen Zhao; Yong Wang; Han Xu; Songhai Li; Ming Li; et al. (Science China Life Sciences, 2021)

Air pollution characteristics, health risks, and source analysis in Shanxi Province, China - Hui Song; Huimin Zhuo; Sanze Fu; Lijun Ren (Environmental Geochemistry and Health, 2021)

Bisabolane sesquiterpenes from Clausena sanki with their potential anti-inflammatory activities - Shi Hu; Yan-Lei Ma; Jia-Ming Guo; Qing Wen; Gui Yan; Shuo Yang; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2020)

Effects of Different Stress Treatments on the Total Terpene Trilactone Content and Expression Levels of Key Genes in Ginkgo biloba Leaves - Jiarui Zheng; Xian Zhang; Mingyue Fu; Hui Zeng; Jiabao Ye; Weiwei Zhang; Yongling Liao; Feng Xu (Plant Molecular Biology Reporter, 2020)

Correction to: Involvement of proBDNF in Monocytes/Macrophages with Gastrointestinal Disorders in Depressive Mice - Yun-Qing Yu; Yan-Ling Zhang; Zhe Wang; Yu Liu; Hui Li; Chang-Qi Li; Xin-Fu Zhou; Zhao-Lan Hu; Ru-Ping Dai (Neurotoxicity Research, 2020)

Involvement of proBDNF in Monocytes/Macrophages with Gastrointestinal Disorders in Depressive Mice - Yun-Qing Yu; Yan-Ling Zhang; Zhe Wang; Yu Liu; Hui Li; Xin-Fu Zhou; Zhao-Lan Hu; Ru-Ping Dai (Neurotoxicity Research, 2020)

CARD9 Deficiency in a Chinese Man with Cutaneous Mucormycosis, Recurrent Deep Dermatophytosis and a Review of the Literature - Xiaopo Wang; Hui Ding; Zhiming Chen; Xuesi Zeng; Jianfang Sun; Hao Chen; Meihua Fu (Mycopathologia, 2020)

Patterns of mitochondrial DNA fragmentation in bread wheat (Triticum aestivum L.) seeds under ex situ genebank storage and artificial aging - Yong-Bi Fu; Zaheer Ahmed; Hui Yang; Carolee Horbach; Gregory W. Peterson (Genetic Resources and Crop Evolution, 2020)

Does underweight amplify the relationship between short-term particulate matter exposure and blood pressure in children and adolescents: a large cross-sectional study in a metropolis of China - Jia Hu; Han Fu; Hui Shen; Chen-gang Teng; Wei Yang; Hai-bing Yang; Fang Liu (Environmental Science and Pollution Research, 2020)

SNP of AHSA2 gene in three cattle breeds using snapshot technology - Shu-Zhu Cheng; E. Guang-Xin; Cheng-Li Liu; Wang-Dui Basang; Yan-Bin Zhu; Ri-Su Na; Yan-Guo Han; Yan Zeng; Xiao Wang; Wei-Wei Ni; Bai-Gao Yang; Xing-Hai Duan; et al. (Journal of Genetics, 2020)

3D inversion of audio-magnetotelluric data for mineral exploration: A case study of Layikeleke buried porphyry copper deposit, Xinjiang, China - Fu Guang-Ming; Yan Jia-Yong; Chen Hui; Meng Gui-Xiang; Yu Hui; Luo Fan; Luo Lei; Tao Xin (Applied Geophysics, 2020)

Petrogenesis of post-collisional magmatism at the Carboniferous–Permian boundary in central Inner Mongolia, NE China: insights into when the Hegenshan Ocean closed? - Lu Lu; Yong Qin; Kai-Jun Zhang; Chun-Yuan Han; Zhuang-Fu Li; Tao Wei; Zheng-Hui Qu; Yong-Zhong Xu (International Geology Review, 2020)

Role of BrSDG8 on bolting in Chinese cabbage (Brassica rapa) - Wei Fu; Shengnan Huang; Yue Gao; Meidi Zhang; Gaoyang Qu; Nan Wang; Zhiyong Liu; Hui Feng (Theoretical and Applied Genetics, 2020)

Effects of plant size on the growth of the submersed macrophyte Vallisneria spinulosa S.Z.Yan at different light intensities: implications for lake restoration - Guixiang Yuan; Hui Fu; Meihong Zhang; Qian Lou; Taotao Dai; Erik Jeppesen (Hydrobiologia, 2020)

Experimentally Induced Sepsis Causes Extensive Hypomyelination in the Prefrontal Cortex and Hippocampus in Neonatal Rats - Peixian Huang; Xuan Chen; Xiaoli Hu; Qiuping Zhou; Lanfen Lin; Shuqi Jiang; Hui Fu; Yajie Xiong; Hongke Zeng; Ming Fang; Chunbo Chen; Yiyu Deng (NeuroMolecular Medicine, 2020)

Prenylated isoflavones with potential antiproliferative activities from Mappianthus iodoides - Yan-Ping Liu; Li-Li Sun; Xiang-Lin Zhang; Hai-Yuan Niu; Zheng-Hong Pan; Yan-Hui Fu (Natural Product Research, 2020)

Distribution patterns and source identification for heavy metals in Mirs Bay of Hong Kong in China - Mei-Lin Wu; Hao Cheng; Hui Zhao; Fu-Lin Sun; Yu-Tu Wang; Jian-Ping Yin; Jiao Fei; Cui-Ci Sun; You-Shao Wang (Ecotoxicology, 2020)

Phytoplankton community, structure and succession delineated by partial least square regression in Daya Bay, South China Sea - Mei-Lin Wu; Yu-Tu Wang; Hao Cheng; Fu-lin Sun; Jiao Fei; Cui-Ci Sun; Jian-Ping Yin; Hui Zhao; You-Shao Wang (Ecotoxicology, 2020)

Decreased sustained attention, processing speed and verbal learning memory in patients with insomnia in Chinese young and middle-aged adults: a cross-sectional study - Xie Chen; Cai-Lan Hou; Shi-Bin Wang; Zhuo-Hui Huang; Ying-Hua Huang; Xue-Li Li; Fu-Jun Jia (Sleep and Biological Rhythms, 2020)

The economic loss of health effect damages from PM2.5 pollution in the Central Plains Urban Agglomeration - Xiangshan Fu; Li Li; Yalin Lei; Sanmang Wu; Dan Yan; Ximing Luo; Hui Luo (Environmental Science and Pollution Research, 2020)

Examination of a coupling coordination relationship between urbanization and the eco-environment: a case study in Qingdao, China - Sanze Fu; Huimin Zhuo; Hui Song; Jianchun Wang; Lijun Ren (Environmental Science and Pollution Research, 2020)

Dynamic behaviour and damage characteristics of loess in Xianyang, China - Huie Chen; Hui Li; Rui Fu; Xiaoqing Yuan (Bulletin of Engineering Geology and the Environment, 2020)

Phytochemical constituents of the pericarps of Illicium difengpi and their anti-inflammatory activity - De-Sheng Ning; Yu-Xia Fu; Li-Yan Peng; Hui Tang; Lian-Chun Li; Xing-De Wu; Yu-Song Huang; Zheng-Hong Pan (Natural Product Research, 2020)

Bioactive Eudesmane sesquiterpenes from Artabotrys hongkongensis Hance - Qing Wen; Yan-Ping Liu; Gui Yan; Shuo Yang; Shi Hu; Jing Hua; Wen-Qing Yin; Guang-Ying Chen; Yan-Hui Fu (Natural Product Research, 2020)

Enhanced pyrogallol toxicity to cyanobacterium Microcystis aeruginosa with increasing alkalinity - Yunni Gao; Qinqin Fu; Jing Lu; Hui Yang; Philip T. Orr; Fang Zhang; Jing Dong; Man Zhang; Qianhong Gu; Chuanjiang Zhou; Michele A. Burford (Journal of Applied Phycology, 2020)

Influence of Aphis gossypii feeding on defense strategy of native and introduced populations of Ageratina adenophora - Ying Lin; Shu-Qi He; Zhi-Hui Lu; Yu-Lin Gao; Yan-Ru Duan; Zheng-Yue Li; Bin Chen; Fu-Rong Gui (Arthropod-Plant Interactions, 2020)

Epidemiology and HBGA-susceptibility investigation of a G9P[8] rotavirus outbreak in a school in Lechang, China - Lun-Ai Guo; Meng Zhang; Yu-zhen Hou; Haitao Hu; Ling Fang; Ming Tan; Qiong Huang; Hui Li; Li-Mei Sun; Xi Jiang; Wen-Fang Tan; Shixing Tang; et al. (Archives of Virology, 2020)

Identification and characterization of two morphologically distinct stem cell subpopulations from human urine samples - An-Jing Chen; Jin-Kui Pi; Jun-Gen Hu; Yi-Zhou Huang; Hong-Wei Gao; Sheng-Fu Li; Jesse Li-Ling; Hui-Qi Xie (Science China Life Sciences, 2020)

Possible aerosol transmission of COVID-19 and special precautions in dentistry - Zi-yu Ge; Lu-ming Yang; Jia-jia Xia; Xiao-hui Fu; Yan-zhen Zhang (Journal of Zhejiang University-SCIENCE B, 2020)

Transcriptome Analysis Reveals the Effects of Chinese Chive (Allium tuberosum R.) Extract on Fusarium oxysporum f. sp. radicis-lycopersici Spore Germination - Xiu Zhang; Hui Wang; Wenying Zhu; Wenli Li; Fu Wang (Current Microbiology, 2020)

Exogenous salicylic acid alleviates halosulfuron-methyl toxicity by coordinating the antioxidant system and improving photosynthesis in soybean (Glycine max Merr.) - Yuan-Fu Li; Lu-Lu Huang; Xiao-Liang Liu; Xue-Sheng Li; Hui-Hua Tan (Acta Physiologiae Plantarum, 2020)

Serum Uric Acid Levels and Risk of Intracranial Atherosclerotic Stenosis: A Cross-Sectional Study - Lin Li; Jun-Xia Zhu; Xiao-He Hou; Ya-Hui Ma; Wei Xu; Chen-Chen Tan; Fu-Rong Sun; Hong-Qi Li; Qiang Dong; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2020)

Brain-Wide Shape Reconstruction of a Traced Neuron Using the Convex Image Segmentation Method - Shiwei Li; Tingwei Quan; Hang Zhou; Qing Huang; Tao Guan; Yijun Chen; Cheng Xu; Hongtao Kang; Anan Li; Ling Fu; Qingming Luo; Hui Gong; et al. (Neuroinformatics, 2020)

Cascading effects of elevation, soil moisture and soil nutrients on plant traits and ecosystem multi-functioning in Poyang Lake wetland, China - Hui Fu; Guixiang Yuan; Dabing Ge; Wei Li; Dongsheng Zou; Zhenrong Huang; Aiping Wu; Qiaolin Liu; Erik Jeppesen (Aquatic Sciences, 2020)

Identification and validation of the superior alleles for wheat kernel traits detected by genome-wide association study under different nitrogen environments - Na Zhang; Xilan Zhang; Liqiang Song; Qiannan Su; Shuai Zhang; Jiajia Liu; Wei Zhang; Xiaoyi Fu; Minghui Zhao; Lijing Sun; Jun Ji; Wenchen Qiao; et al. (Euphytica, 2020)

Identification of De Novo JAK2 and MAPK7 Mutations Related to Autism Spectrum Disorder Using Whole-Exome Sequencing in a Chinese Child and Adolescent Trio-Based Sample - Jian Jiao; Manxue Zhang; Pingyuan Yang; Yan Huang; Xiao Hu; Jia Cai; Chan Yang; Mingjing Situ; Hui Zhang; Lei Fu; Kuifang Guo; Yi Huang (Journal of Molecular Neuroscience, 2020)
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with high phenotypic and genetic heterogeneity. Whole-exome sequencing studies have shown that de novo single-nucleotide variations (SNVs) play an important role in sporadic ASD. The present study aimed to search for de novo SNVs using whole-exome sequencing in 59 unrelated Chinese ASD sporadic trios, and found 24 genes (including five reported ASD candidate genes CACNA1D , ACHE , YY1 , TTN , and FBXO11 ) with de novo harmful SNVs. Five genes ( CACNA1D , JAK2 , ACHE , MAPK7 , and PRKAG2 ) classified as “medium-confidence” genes were found to be related to ASD using the Phenolyzer gene analysis tool, which predicts the correlation between the candidate genes and the ASD phenotype. De novo SNVs in JAK2 , MAPK7 , and PRKAG2 were first found in ASD. Both JAK2 and MAPK7 were involved in the regulation of the MAPK signaling pathway. Gene co-expression and inter-gene interaction networks were constructed and gene expression data in different brain regions were further extracted, revealing that JAK2 and MAPK7 genes were associated with certain previously reported ASD genes and played an important role in early brain development. The findings of this study suggest that the aforementioned five reported ASD genes and JAK2 and MAPK7 may be related to ASD susceptibility. Further investigations of expression studies in cellular and animal models are needed to explore the mechanism underlying the involvement of JAK2 and MAPK7 in ASD.

Identifying common genome-wide risk genes for major psychiatric traits - Sha Liu; Shuquan Rao; Yong Xu; Jun Li; Hailiang Huang; Xu Zhang; Hui Fu; Qiang Wang; Hongbao Cao; Ancha Baranova; Chunhui Jin; Fuquan Zhang (Human Genetics, 2020)

Two new norneolignans from Callicarpa kwangtungensis - Hong-Yu Bi; Chun-Liang Xu; Hui-Zheng Fu; Zhi-Qiang Zhou; Rui-Jian Zhong; Mian Dai; Dong Wang (Natural Product Research, 2020)

Geographically isolated Colorado potato beetle mediating distinct defense responses in potato is associated with the alteration of gut microbiota - Jie Wang; Zhou Gao; Mingyu Yang; Rongrong Xue; Hui Yan; Kaiyun Fu; Zhaojuan Zhang; Wenchao Guo; Gary W. Felton; Rensen Zeng (Journal of Pest Science, 2020)

Source analysis and risk assessment of heavy metals in development zones: a case study in Rizhao, China - Huimin Zhuo; Xu Wang; Heng Liu; Sanze Fu; Hui Song; Lijun Ren (Environmental Geochemistry and Health, 2020)

Preparation and In vitro Evaluation of FDM 3D-Printed Ellipsoid-Shaped Gastric Floating Tablets with Low Infill Percentages - Di Chen; Xiang-Yu Xu; Rui Li; Gen-Ao Zang; Yue Zhang; Ming-Rui Wang; Meng-Fei Xiong; Jia-Rui Xu; Ting Wang; Hui Fu; Qin Hu; Bin Wu; et al. (AAPS PharmSciTech, 2020)

Carbazole alkaloids from Clausena emarginata with their potential antiproliferative activities - Yan-Hui Fu; Yan-Lei Ma; Gui Yan; Qing Wen; Shi Hu; Zhi-Hua Jiang; Jin-Ying Tang; Yan-Ping Liu (Natural Product Research, 2019)

Transport of uranium(VI) in red soil in South China: influence of initial pH and carbonate concentration - Haiying Fu; Dexin Ding; Yang Sui; Hui Zhang; Nan Hu; Feng Li; Zhongran Dai; Guangyue Li; Yongjun Ye; Yongdong Wang (Environmental Science and Pollution Research, 2019)

Short hairpin RNAs targeting M and N genes reduce replication of porcine deltacoronavirus in ST cells - Wen-yuan Gu; Yan Li; Bao-jing Liu; Jing Wang; Guang-fu Yuan; Shao-jie Chen; Yu-Zhu Zuo; Jing-Hui Fan (Virus Genes, 2019)

Application of Cas12a and nCas9-activation-induced cytidine deaminase for genome editing and as a non-sexual strategy to generate homozygous/multiplex edited plants in the allotetraploid genome of tobacco - Chen-Tran Hsu; Yu-Jung Cheng; Yu-Hsua Yuan; Wei-Fon Hung; Qiao-Wei Cheng; Fu-Hui Wu; Lan-Ying Lee; Stanton B. Gelvin; Choun-Sea Lin (Plant Molecular Biology, 2019)

Two-factor ANOVA of SSH and RNA-seq analysis reveal development-associated Pi-starvation genes in oilseed rape - Zhong-Wei Zhang; Ling-Yang Feng; Jian-Hui Wang; Yu-Fan Fu; Xin Cai; Chang-Quan Wang; Jun-Bo Du; Ming Yuan; Yang-Er Chen; Pei-Zhou Xu; Ting Lan; Guang-Deng Chen; et al. (Planta, 2019)

Upregulation of proBDNF in the Mesenteric Lymph Nodes in Septic Mice - Zhe Wang; Jia-Li Wu; Feng Zhong; Yu Liu; Yun-Qing Yu; Jing-Jing Sun; Shuang Wang; Hui Li; Xin-Fu Zhou; Zhao-Lan Hu; Ru-Ping Dai (Neurotoxicity Research, 2019)

Panax notoginsenoside Rb1 Restores the Neurotrophic Imbalance Following Photothrombotic Stroke in Rats - Chun-Yan Yang; Jian-Yu Yang; Yun-Xia Xiong; Xue-Feng Zhuang; Hui Su; Sheng Hu; Jia-Qing Ma; Xin-Fu Zhou; Hai-Yun Luo; Jun Sun (Neurotoxicity Research, 2019)

Identifying Weak Signals in Inhomogeneous Neuronal Images for Large-Scale Tracing of Sparsely Distributed Neurites - Shiwei Li; Tingwei Quan; Hang Zhou; FangFang Yin; Anan Li; Ling Fu; Qingming Luo; Hui Gong; Shaoqun Zeng (Neuroinformatics, 2019)

Soil heavy metal contamination and health risk assessment associated with development zones in Shandong, China - Huimin Zhuo; Sanze Fu; Heng Liu; Hui Song; Lijun Ren (Environmental Science and Pollution Research, 2019)

A simple and reliable method for creating PCR-detectable mutants in Arabidopsis with the polycistronic tRNA–gRNA CRISPR/Cas9 system - Liangliang Hui; Min Zhao; Junqi He; Yingying Hu; Yanshuang Huo; Houyan Hao; Yaqi Hao; Weining Zhu; Yuhua Wang; Min Xu; Aigen Fu (Acta Physiologiae Plantarum, 2019)
To develop an easy and robust method for creating genetically stable and easily detectable Arabidopsis mutants, we adopted the polycistronic tRNA–gRNA CRISPR/Cas9 (PTG/Cas9) system, a multiplex gene-editing tool in rice, with PTOX as the reporter gene. The PTG/Cas9 system has a great potential in generating large deletions detectable by PCR, which greatly simplifies the laborious work of mutant screening. We constructed a PTOX –PTG/Cas9 system with five gRNAs and introduced it into Arabidopsis . At T1 generation, 24.4% of transgenic plants were chimeric with PCR-detectable deletions in PTOX locus, but no homozygous mutant was found, indicating that gene editing occurred predominantly in somatic cells. After a self-cross propagation, 60% of T1 chimeric plants were able to produce homozygous, heterozygous, or bi-allelic ptox offsprings. Inheritable homozygous ptox mutants without Cas9 gene can be obtained earliest at T2 generation. We further targeted five other genes using the same procedure and achieved homozygous Cas9-free mutants with large deletions for all genes within three generations. We established a standard and reliable protocol to generate stable inherited deletion mutants in 2–3 generations along with simple PCR screening methods. We conclude that the rice PTG/Cas9 system is an efficient, easy, and rapid tool to edit genes in Arabidopsis . We propose that it could be applied to other genes in Arabidopsis , and it might have the potential to edit genes in other plant species as well.

Furanocoumarins with potential antiproliferative activities from Clausena lenis - Yan-Ping Liu; Qing Wen; Shi Hu; Yan-Lei Ma; Zhi-Hua Jiang; Jin-Ying Tang; Yan-Hui Fu; Shen-Xiang Qiu (Natural Product Research, 2019)

Seroprevalence of porcine bocavirus in pigs in north-central China using a recombinant-NP1-protein-based indirect ELISA - Qian-Kai Shi; Jian-Lou Zhang; Wen-Yuan Gu; Lin-Shan Hou; Guang-Fu Yuan; Shao-Jie Chen; Jing-Hui Fan; Yu-Zhu Zuo (Archives of Virology, 2019)

Metabolomics reveals the drought-tolerance mechanism in wild soybean (Glycine soja) - Xiaoxia Wang; Rui Guo; Mingxia Li; Yuan Liu; Mingli Zhao; Hui Fu; Xueying Liu; Shiyao Wang; Lianxuan Shi (Acta Physiologiae Plantarum, 2019)

Biologically active oligostilbenes from the stems of Vatica mangachapoi and chemotaxonomic significance - Shou-Yuan Wu; Yan-Hui Fu; Qi Zhou; Meng Bai; Guang-Ying Chen; Chang-Ri Han; Xiao-Ping Song (Natural Product Research, 2019)

Progressive multifocal leukoencephalopathy in a renal transplant patient - Tsu-Chen Lin; Mei-Yi Wu; Hui-Tzung Luh; Shiou-Fu Lin; Chien-Min Lin; Ying-Chi Tseng; Yung-Ching Liu; Mai-Szu Wu (Journal of NeuroVirology, 2019)

Measurements and Distribution of Atmospheric Particulate-Bound Mercury: A Review - Hui Zhang; Xuewu Fu; Xun Wang; Xinbin Feng (Bulletin of Environmental Contamination and Toxicology, 2019)

Correction to: Measurements and Distribution of Atmospheric Particulate‑Bound Mercury: A Review - Hui Zhang; Xuewu Fu; Xun Wang; Xinbin Feng (Bulletin of Environmental Contamination and Toxicology, 2019)

Evolutionary and functional implications of 3′ untranslated region length of mRNAs by comprehensive investigation among four taxonomically diverse metazoan species - Wei Wang; Dong-hui Fang; Jia Gan; Yi Shi; Hui Tang; Huai Wang; Mao-zhong Fu; Jun Yi (Genes & Genomics, 2019)

Effect of male sterile and fertile cytoplasm on nuclear DNA methylation in hybrid rice - Asif Ali; Yun Li; Hui Chen; Peizhou Xu; Hongyu Zhang; Xiaoqiong Chen; Liao Yongxiang; Shaohong Fu; Tingkai Wu; Muhammad Zafar Iqbal; Muhammad Umer Farooq; Xianjun Wu (Acta Physiologiae Plantarum, 2019)

Two new noroleanane-type triterpenoid saponins from the stems of Stauntonia chinensis - Tong-Tong Feng; Hui-Zheng Fu; Yi-Sheng Yang; Zhi-Qiang Zhou; Mian Dai; Hong-Yu Bi; Dong Wang (Natural Product Research, 2019)

Dynamic Response of Offshore Open-Ended Pile under Lateral Cyclic Loadings - Junwei Liu; Zhen Guo; Na Zhu; Hui Zhao; Ankit Garg; Longfei Xu; Tao Liu; Changchun Fu (Journal of Marine Science and Engineering, 2019)
Foundations for offshore wind turbines (OWTs) are mainly open-ended piles that are subjected to cyclic loadings caused by winds, waves and currents. This study aims to investigate the dynamic responses of open-ended pipe pile under lateral cyclic loadings, as well as the characteristics of the soil plug and surrounding soil. Both large-scale indoor model test and discrete element simulation were adopted in this study. The test results show that the resistance of each part of the pipe pile increases linearly with depth during the process of pile driving. The pile side resistance degradation effect was also observed along with the friction fatigue. The soil plug formation rate decreases gradually with an increase in the pile depth. The influence range in the surrounding soil is about 5~6 times of the pile diameter. The cumulative displacement of the pile head increases with the number of cycles. Lateral tangential stiffness and lateral ultimate bearing capacity decreases with an increase in number of cycles. The severe disturbance range of soil around the pile is 2~3 times of the pile diameter. The center of rotation of the pile body is about 0.8 times of the pile body depth. The side frictional resistance and lateral pressure of the pile body is found to fluctuate along the pile body. Additionally, the lateral pressure and side friction resistance decreases gradually with decreasing tendency of the former more than the latter.

Genome-wide investigation of the MADS gene family and dehulling genes in tartary buckwheat (Fagopyrum tataricum) - Moyang Liu; Qiankun Fu; Zhaotang Ma; Wenjun Sun; Li Huang; Qi Wu; Zizhong Tang; Tongliang Bu; Chenglei Li; Hui Chen (Planta, 2019)

Effects of nutrient enrichment and Bellamya aeruginosa (Reeve) presence on three submerged macrophytes - Wei Li; Hui Fu; Yujie Li; Weihua Nie; Guixiang Yuan; Guiqing Gao; Houbao Fan; Jiayou Zhong (Hydrobiologia, 2019)

Cinnamaldehyde inhibit Escherichia coli associated with membrane disruption and oxidative damage - Tian-Fu He; Lang-Hong Wang; De-bao Niu; Qing-hui Wen; Xin-An Zeng (Archives of Microbiology, 2019)

Structurally diverse diterpenoids from Trigonostemon howii - Yan-Ping Liu; Qing Wen; Shi Hu; Yan-Lei Ma; Zhi-Hua Jiang; Jin-Ying Tang; Yan-Hui Fu (Natural Product Research, 2019)

AG1031 induces apoptosis through suppressing SIRT1/p53 pathway in human neuroblastoma cells - Jingxuan Fu; Hui Zhang; Yuling Zhang; Tao Zhang (Molecular and Cellular Biochemistry, 2019)

Dexamethasone protects the glycocalyx on the kidney microvascular endothelium during severe acute pancreatitis - Wen-qiao Yu; Shao-yang Zhang; Shui-qiao Fu; Qing-hui Fu; Wei-na Lu; Jian Zhang; Zhong-yan Liang; Yun Zhang; Ting-bo Liang (Journal of Zhejiang University-SCIENCE B, 2019)

Nonstationary inversion-based directional deconvolution of airgun array signature - Hao Li; Guo-Fa Li; Xiang-Hui Guo; Xi-Ping Sun; Jian-Fu Wang (Applied Geophysics, 2019)

A new morphinandienone alkaloid from the stems of Fissistigma tungfangense - Qi Zhou; Yan-Hui Fu; Yu-Qin Zhang; Shou-Yuan Wu; Xiao-Ping Song; Wei Xu; Guang-Ying Chen (Natural Product Research, 2019)

Genome-wide detection of additional fetal chromosomal abnormalities by cell-free DNA testing of 15,626 consecutive pregnant women - Hong Yao; Ya Gao; Jia Zhao; Rong Zhang; Huixin Xu; Huamei Hu; Yanmei Luo; Yuying Yuan; Meili Fu; Hongyun Zhang; Hui Jiang; Wei Wang; et al. (Science China Life Sciences, 2019)

Current genetic diversity in eight local Chinese sheep populations - Guang-Xin E; Yue-Hui Ma; Ming-Xing Chu; Qiong-Hua Hong; Yong-Fu Huang (Molecular Biology Reports, 2019)

Integrative genomic analysis predicts novel functional enhancer-SNPs for bone mineral density - Chuan Qiu; Hui Shen; Xiaoying Fu; Chao Xu; Qing Tian; Hongwen Deng (Human Genetics, 2019)

Identification a novel clinical biomarker in early diagnosis of human non-small cell lung cancer - Yanxia Jin; Yajun Yang; Yanting Su; Xiangdong Ye; Wei Liu; Qing Yang; Jie Wang; Xiangning Fu; Yongsheng Gong; Hui Sun (Glycoconjugate Journal, 2019)

Luminescence chronology of the Palaeolithic–Neolithic transition in the Yujiagou site at the Nihewan Basin, northern China - Xue Rui; Yu‐Jie Guo; Jia‐Fu Zhang; Yue Hu; Hui‐Jie Mei; You‐Ping Wang; Fei Xie; Bo Li (Journal of Quaternary Science, 2019)
The relationship between the Palaeolithic–Neolithic cultural transition and environmental changes is important for understanding human history. However, the timing and nature of human behaviour at the transition, and their relationship to local environmental conditions, remain poorly understood. The Yujiagou archaeological site in the Nihewan Basin, northern China, provides valuable chronological and archaeological information about cultural changes in northern China due to its continuous archaeological sequence of cultural layers from the Palaeolithic to Neolithic. In this study, we apply post‐infrared infrared stimulated luminescence (pIRIR) dating on individual feldspar grains to date the Yujiagou deposits. We provide a revised chronology for the archaeological sequence at the site. We combine these results with multi‐proxy climatic indicators to gain insights into palaeoenvironmental changes in the region. The results show that the age of the artefact‐bearing deposits ranges from 13.5 to 9.7 ka. Polished stones and pottery begin to occur in the archaeological layer around 13 ka, corresponding to a transitional period when the local climate changed from cold to warm. This site provides evidence for understanding the process that led to the regional transition from hunter‐gathering to farming.

Impact of Tryptophan Oxidation in Complementarity-Determining Regions of Two Monoclonal Antibodies on Structure-Function Characterized by Hydrogen-Deuterium Exchange Mass Spectrometry and Surface Plasmon Resonance - Tyler Hageman; Hui Wei; Patrick Kuehne; Jinmei Fu; Richard Ludwig; Li Tao; Anthony Leone; Marcel Zocher; Tapan K. Das (Pharmaceutical Research, 2019)

A Genome-Wide Association Study of α-Synuclein Levels in Cerebrospinal Fluid - Xiao-ling Zhong; Jie-Qiong Li; Li Sun; Ya-Qing Li; Hui-Fu Wang; Xi-Peng Cao; Chen-Chen Tan; Ling Wang; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2019)

Cytotoxic indole alkaloids from Nauclea orientalis - Yan-Ping Liu; Peng-Kun Ju; Jin-Tao Long; Liang Lai; Wan-Hui Zhao; Chao Zhang; Zhi-Jie Zhang; Yan-Hui Fu (Natural Product Research, 2018)

A new insecticidal havanensin-type limonoid from the roots of Trichilia sinensis Bentv. - Shou-Bai Liu; Hui-Qin Chen; Gang Feng; Zhi-Kai Guo; Cai-hong Cai; Jun Wang; Wen-Li Mei; Hao-Fu Dai (Natural Product Research, 2018)

Reduced hsa-miR-124-3p levels are associated with the poor survival of patients with hepatocellular carcinoma - Hui-Deng Long; Yu-Shui Ma; Hui-Qiong Yang; Shao-Bo Xue; Ji-Bin Liu; Fei Yu; Zhong-Wei Lv; Ji-Yu Li; Ru-Ting Xie; Zheng-Yan Chang; Gai-Xia Lu; Wen-Ting Xie; et al. (Molecular Biology Reports, 2018)

A new polyoxygenated abietane diterpenoid from the rattans of Bauhinia championii (Benth.) Benth - Li-Ping Hua; Yu-Qin Zhang; Miao Ye; Wen Xu; Xiao-Ying Wang; Yan-Hui Fu; Wei Xu (Natural Product Research, 2018)

Different CO2 acclimation strategies in juvenile and mature leaves of Ottelia alismoides - Wen Min Huang; Hui Shao; Si Ning Zhou; Qin Zhou; Wen Long Fu; Ting Zhang; Hong Sheng Jiang; Wei Li; Brigitte Gontero; Stephen C. Maberly (Photosynthesis Research, 2018)

Simplified method for estimating throw radius of rotating sprinklers on sloping land - Lin Zhang; Boyang Fu; Xin Hui; Naiwang Ren (Irrigation Science, 2018)

Total and available metal concentrations in soils from six long-term fertilization sites across China - Dong-Xing Guan; Fu-Sheng Sun; Guang-Hui Yu; Matthew L. Polizzotto; Yun-Gen Liu (Environmental Science and Pollution Research, 2018)

A new abietane diterpenoid from the roots of Tripterygium regelii - Zhi-Hua Jiang; Yan-Ping Liu; Miao He; Jin-Hua Zhao; Ting-Ting Wang; Xing-Yang Feng; Hao Yue; Ren-Bo An; Yan-Hui Fu (Natural Product Research, 2018)

Alcohol-induced conditioned place preference negatively correlates with anxiety-like behavior in adolescent mice: inhibition by a neurokinin-1 receptor antagonist - Hui Huang; Xiaojie Zhang; Xiaoya Fu; Xiangyang Zhang; Bing Lang; Xiaojun Xiang; Wei Hao (Psychopharmacology, 2018)

Global development and trend of wind tunnel research from 1991 to 2014: a bibliometric analysis - Ziwei Mo; Hui-Zhen Fu; Yuh-Shan Ho (Environmental Science and Pollution Research, 2018)

Bioactive furanocoumarins from the stems and leaves of Clausena hainanensis - Yan-Lei Ma; Chao Zhang; Wan-Hui Zhao; Shi Shi; Dan-Nv He; Pan Zhang; Xiao-Hong Liu; Ting-Ting Han; Yan-Hui Fu; Yan-Ping Liu (Natural Product Research, 2018)

Novel thioredoxin reductase inhibitor butaselen inhibits tumorigenesis by down-regulating programmed death-ligand 1 expression - Qiao Zou; Yi-fan Chen; Xiao-qing Zheng; Suo-fu Ye; Bin-yuan Xu; Yu-xi Liu; Hui-hui Zeng (Journal of Zhejiang University-SCIENCE B, 2018)

Phylogeographic analysis of porcine reproductive and respiratory syndrome virus 1 in Guangdong province, Southern China - Shao-Lun Zhai; Tao Lin; Xia Zhou; Zhang-Fu Pei; Zu-Zhang Wei; He Zhang; Xiao-Hui Wen; Qin-Ling Chen; Dian-Hong Lv; Wen-Kang Wei (Archives of Virology, 2018)

Poststack internal multiples attenuation based on virtual events - Meng Chen; Jia-Hui Liu; Yong-Fu Cui; Tian-Yue Hu; Fei-Xu Chen; Wei-Kang Kuang; Zhen Zhang (Applied Geophysics, 2018)

Active earth pressure on translating rigid retaining structures considering soil arching effect - Yi-tao Zhou; Qing-sheng Chen; Fu-quan Chen; Xiao-hui Xue; Sudip Basack (European Journal of Environmental and Civil Engineering, 2018)

Combined prednisone and levothyroxine improve treatment of severe thrombocytopenia in hepatitis B with compensatory cirrhosis accompanied by subclinical and overt hypothyroidism - Jing Xue; Ru Feng; Haixia Fu; Qian Jiang; Hao Jiang; Jing Lu; Hui Liu; Jingwen Wang; Ting Niu; Xin Wang; Yandi Xie; Hao Wang; et al. (Science China Life Sciences, 2018)

Biological floating bed and bio-contact oxidation processes for landscape water treatment: simultaneous removal of Microcystis aeruginosa, TOC, nitrogen and phosphorus - Jun feng Su; Dong hui Liang; Le Fu; Li Wei; Min Ma (Environmental Science and Pollution Research, 2018)

A new polyoxygenated cyclohexene derivative from Artabotrys hainanensis - Jin-Ying Tang; Yan-Ping Liu; Peng-Kun Ju; Xiu-Lan Luo; Zhi-Jie Zhang; Peng Ren; Liang Lai; Guang-Ying Chen; Yan-Hui Fu (Natural Product Research, 2018)

Genetic structure of six cattle populations revealed by transcriptome-wide SNPs and gene expression - Wei Wang; Huai Wang; Hui Tang; Jia Gan; Changgeng Shi; Qing Lu; Donghui Fang; Jun Yi; Maozhong Fu (Genes & Genomics, 2018)

Front Cover - James A. Lutz; Tucker J. Furniss; Daniel J. Johnson; Stuart J. Davies; David Allen; Alfonso Alonso; Kristina J. Anderson‐Teixeira; Ana Andrade; Jennifer Baltzer; Kendall M. L. Becker; Erika M. Blomdahl; Norman A. Bourg; et al. (Global Ecology and Biogeography, 2018)

Global importance of large‐diameter trees - James A. Lutz; Tucker J. Furniss; Daniel J. Johnson; Stuart J. Davies; David Allen; Alfonso Alonso; Kristina J. Anderson‐Teixeira; Ana Andrade; Jennifer Baltzer; Kendall M. L. Becker; Erika M. Blomdahl; Norman A. Bourg; et al. (Global Ecology and Biogeography, 2018)
Aim To examine the contribution of large‐diameter trees to biomass, stand structure, and species richness across forest biomes. Location Global. Time period Early 21st century. Major taxa studied Woody plants. Methods We examined the contribution of large trees to forest density, richness and biomass using a global network of 48 large (from 2 to 60 ha) forest plots representing 5,601,473 stems across 9,298 species and 210 plant families. This contribution was assessed using three metrics: the largest 1% of trees ≥ 1 cm diameter at breast height (DBH), all trees ≥ 60 cm DBH, and those rank‐ordered largest trees that cumulatively comprise 50% of forest biomass. Results Averaged across these 48 forest plots, the largest 1% of trees ≥ 1 cm DBH comprised 50% of aboveground live biomass, with hectare‐scale standard deviation of 26%. Trees ≥ 60 cm DBH comprised 41% of aboveground live tree biomass. The size of the largest trees correlated with total forest biomass ( r 2 = .62, p r 2 = .45, p r 2 = .33, p r 2 = .17, p = .002). The concentration of biomass in the largest 1% of trees declined with increasing absolute latitude ( r 2 = .46, p r 2 = .31, p r 2 = .26, p Main conclusions Because large‐diameter trees constitute roughly half of the mature forest biomass worldwide, their dynamics and sensitivities to environmental change represent potentially large controls on global forest carbon cycling. We recommend managing forests for conservation of existing large‐diameter trees or those that can soon reach large diameters as a simple way to conserve and potentially enhance ecosystem services.

Effect of Plant Density on Sweet and Biomass Sorghum Production on Semiarid Marginal Land - Chaochen Tang; Chuandong Sun; Fu Du; Feng Chen; Asif Ameen; Tongcheng Fu; Guang Hui Xie (Sugar Tech, 2018)

Functional Role of Matrix gla Protein in Glioma Cell Migration - Mu-Hui Fu; Chih-Yen Wang; Yun-Ti Hsieh; Kuan-Min Fang; Shun-Fen Tzeng (Molecular Neurobiology, 2018)

Highly cited articles in wind tunnel-related research: a bibliometric analysis - Ziwei Mo; Hui-Zhen Fu; Yuh-Shan Ho (Environmental Science and Pollution Research, 2018)

Fatigue Magnification Factors of Arc-Soft-Toe Bracket Joints - Qiang Fu; Huajun Li; Hongqing Wang; Shuqing Wang; Dejiang Li; Qun Li; Hui Fang (Journal of Ocean University of China, 2018)

Transdimensional Bayesian inversion of time-domain airborne EM data - Zong-Hui Gao; Chang-Chun Yin; Yan-Fu Qi; Bo Zhang; Xiu-Yan Ren; Yong-Chao Lu (Applied Geophysics, 2018)

Identification, characterization and expression analysis of genes involved in steroidal saponin biosynthesis in Dracaena cambodiana - Jia-Hong Zhu; Hui-Liang Li; Dong Guo; Ying Wang; Hao-Fu Dai; Wen-Li Mei; Shi-Qing Peng (Journal of Plant Research, 2018)

A new dihydrochalcone glycoside from the stems of Homalium stenophyllum - Shou-Yuan Wu; Yan-Hui Fu; Qi Zhou; Meng Bai; Guang-Ying Chen; Chang-Ri Han; Xiao-Ping Song (Natural Product Research, 2018)

Heterogeneous expression of the cotton R2R3-MYB transcription factor GbMYB60 increases salt sensitivity in transgenic Arabidopsis - Fu-Chun Xu; Hui-Li Liu; Yun-Yun Xu; Jing-Ruo Zhao; Ya-Wei Guo; Lu Long; Wei Gao; Chun-Peng Song (Plant Cell, Tissue and Organ Culture (PCTOC), 2018)

Cadmium and lead accumulations and agronomic quality of a newly bred pollution-safe cultivar (PSC) of water spinach - Ying-Ying Huang; Yang-Xiu Mu; Chun-Tao He; Hui-Ling Fu; Xue-Song Wang; Fei-Yue Gong; Zhong-Yi Yang (Environmental Science and Pollution Research, 2018)

Spatial and temporal variation of vegetation phenology and its response to climate changes in Qaidam Basin from 2000 to 2015 - Yang Fu; Hui Chen; Huihui Niu; Siqi Zhang; Yi Yang (Journal of Geographical Sciences, 2018)

Screen for Inhibitors of Crystal Growth to Identify Desirable Carriers for Amorphous Solid Dispersions Containing Felodipine - Jinping Fu; Lin Cui; Congbin Yang; Hui Xiong; Guobin Ren; Xingyuan Ma; Qiufang Jing; Fuzheng Ren (AAPS PharmSciTech, 2018)

Revealing histological and morphological features of female reproductive system in tree shrew (Tupaia belangeri) - Shan Zhong; Shi-yao Zhang; Hui-jie Xing; Xiao-tan Zhang; Guang Wang; Yong-ping Bao; Jiang-nan Fu; Xuesong Yang (Zoomorphology, 2018)

Structural characterisation of a water-soluble polysaccharide from tissue-cultured Dendrobium huoshanense C.Z. Tang et S.J. Cheng - Hua-Yang Si; Nai-Fu Chen; Nai-Dong Chen; Cheng Huang; Jun Li; Hui Wang (Natural Product Research, 2018)

Effect of the dark septate endophytic fungus Acrocalymma vagum on heavy metal content in tobacco leaves - Hui-Qing Jin; Hua-Bing Liu; Ying-Ying Xie; Yong-Gang Zhang; Qing-Quan Xu; Li-Juan Mao; Xin-Jun Li; Jin Chen; Fu-Cheng Lin; Chu-Long Zhang (Symbiosis, 2018)

Albumin-Conjugated Lipid-Based Multilayered Nanoemulsion Improves Drug Specificity and Anti-Inflammatory Potential at the Spinal Cord Injury gSite after Intravenous Administration - Xiao-Gang Chen; Fu Hua; Shou-Guo Wang; Hong-Hui Tang (AAPS PharmSciTech, 2018)

A new isoflavone from the roots of Ficus auriculata - Cui-Cui Qi; Yan-Hui Fu; Wen-Hao Chen; Guang-Ying Chen; Chun-Yan Dai; Xiao-Ping Song; Chang-Ri Han (Natural Product Research, 2018)

Soil physical properties response to tillage practices during summer fallow of dryland winter wheat field on the Loess Plateau - Jian-Fu Xue; Ai-Xia Ren; Hui Li; Zhi-Qiang Gao; Tian-Qing Du (Environmental Science and Pollution Research, 2018)

UV‐B induced biosynthesis of a novel sunscreen compound in solar radiation and desiccation tolerant cyanobacteria - Jin‐Long Shang; Zhong‐Chun Zhang; Xiao‐Yue Yin; Min Chen; Fu‐Hua Hao; Kai Wang; Jun‐Li Feng; Hai‐Feng Xu; Yan‐Chao Yin; Hui‐Ru Tang; Bao‐Sheng Qiu (Environmental Microbiology, 2018)
Summary The small‐molecule sunscreen compounds, mycosporine‐like amino acids (MAAs), have strong ultraviolet (UV) absorption and can protect cyanobacteria against UV‐B damage. However, the molecular mechanism underlying UV‐B signaling and MAA chemical diversity remain largely unclear. Here, we identified a five‐gene cluster for MAA biosynthesis in the solar radiation and desiccation tolerant cyanobacterium Nostoc flagelliforme . A LuxR family protein OrrA was identified as a positive UV‐B responsive regulator binding to the promoter region of this gene cluster. OrrA functions as an activator mediating the UV‐B induced MAA biosynthesis. Overexpression of orrA strengthened its UV‐B tolerance during desiccation, and enhanced the photosynthetic recovery upon rehydration. Heterologous expression of this gene cluster in Anabaena PCC 7120 produces the same MAA as that in field samples of N . flagelliforme . The MAA structure is assigned as mycosporine‐2‐(4‐deoxygadusolyl‐ornithine) with a molecular weight of 756 Da, the structurally unique MAA compound reported to date. This MAA was catalyzed by mysD‐mysC2‐mysC1 encoding proteins from 4‐deoxygadusol, which was synthesized through the catalysis of mysA‐mysB products. Thus, we elucidated the transcriptional mechanism for a novel type MAA biosynthesis in solar radiation and desiccation tolerant cyanobacteria, which shed light on the identification of other components for UV‐B signaling in cyanobacteria.

CASCIRE surveillance network and work on avian influenza viruses - Yuhai Bi; Weifeng Shi; Jianjun Chen; Quanjiao Chen; Zhenghai Ma; Gary Wong; Wenxia Tian; Renfu Yin; Guanghua Fu; Yongchun Yang; William J. Liu; Chuansong Quan; et al. (Science China Life Sciences, 2017)

The nitrate‐reduction gene cluster components exert lineage‐dependent contributions to optimization of Sinorhizobium symbiosis with soybeans - Li Xue Liu; Qin Qin Li; Yun Zeng Zhang; Yue Hu; Jian Jiao; Hui Juan Guo; Xing Xing Zhang; Biliang Zhang; Wen Xin Chen; Chang Fu Tian (Environmental Microbiology, 2017)
Summary Receiving nodulation and nitrogen fixation genes does not guarantee rhizobia an effective symbiosis with legumes. Here, variations in gene content were determined for three Sinorhizobium species showing contrasting symbiotic efficiency on soybeans. A nitrate‐reduction gene cluster absent in S. sojae was found to be essential for symbiotic adaptations of S. fredii and S . sp. III. In S. fredii , the deletion mutation of the nap (nitrate reductase), instead of nir (nitrite reductase) and nor (nitric oxide reductase), led to defects in nitrogen‐fixation (Fix – ). By contrast, none of these core nitrate‐reduction genes were required for the symbiosis of S . sp. III. However, within the same gene cluster, the deletion of hemN1 (encoding oxygen‐independent coproporphyrinogen III oxidase) in both S. fredii and S . sp. III led to the formation of nitrogen‐fixing (Fix + ) but ineffective (Eff – ) nodules. These Fix + /Eff – nodules were characterized by significantly lower enzyme activity of glutamine synthetase indicating rhizobial modulation of nitrogen‐assimilation by plants. A distant homologue of HemN1 from S. sojae can complement this defect in S. fredii and S . sp. III, but exhibited a more pleotropic role in symbiosis establishment. These findings highlighted the lineage‐dependent optimization of symbiotic functions in different rhizobial species associated with the same host.

Role of early environmental enrichment on the social dominance tube test at adulthood in the rat - Wen-Yu Cao; Zhao-Lan Hu; Yang Xu; Wen-Juan Zhang; Fu-Lian Huang; Xiao-Qing Qiao; Yan-Hui Cui; Wei Wan; Xue-qin Wang; Dan Liu; Ru-Ping Dai; Fang Li; et al. (Psychopharmacology, 2017)

Molecular diversity of phenothiazines: design and synthesis of phenothiazine–dithiocarbamate hybrids as potential cell cycle blockers - Dong-Jun Fu; Ruo-Han Zhao; Jia-Huan Li; Jia-Jia Yang; Ruo-Wang Mao; Bo-Wen Wu; Ping Li; Xiao-Lin Zi; Qing-Qing Zhang; Hui-Jie Cai; Sai-Yang Zhang; Yan-Bing Zhang; et al. (Molecular Diversity, 2017)

Characteristics and trends on global environmental monitoring research: a bibliometric analysis based on Science Citation Index Expanded - Di Zhang; Hui-Zhen Fu; Yuh-Shan Ho (Environmental Science and Pollution Research, 2017)

The Physicochemical Investigation of 17β-Estradiol Crystalline Prepared by In Situ pH-Dependent Solubility Technique with Polyvinylpyrrolidone - Hui Xiong; Jinping Fu; Hanjing Sun; Enfu Wang; Yunhui Ding; Guobin Ren; Qiufang Jing; Fuzheng Ren (AAPS PharmSciTech, 2017)

Anti-complementary constituents of Viola kunawarensis - Hui Wang; Wen-Li Cong; Ze-long Fu; Dao-Feng Chen; Qi Wang (Natural Product Research, 2017)

C5a/C5aR Pathway Plays a Vital Role in Brain Inflammatory Injury via Initiating Fgl-2 in Intracerebral Hemorrhage - Bangqing Yuan; Fenlan Fu; Shaokuan Huang; Chuangan Lin; Guang Yang; Kunlong Ma; Hui Shi; Zhao Yang (Molecular Neurobiology, 2017)

Development of Albumin Coupled, Cholesterol Stabilized, Lipid Nanoemulsion of Methotrexate, and TNF-α Inhibitor for Improved In Vivo Efficacy Against Rheumatoid Arthritis - Xiao-yan Li; Hui Li; Yan Zhang; Shan Gao; Chun-ping Dong; Gui-fu Wu (AAPS PharmSciTech, 2017)

A new indole alkaloid with anti-inflammatory activity from Nauclea officinalis - Qing-Long Liu; A-Hong Chen; Jin-Ying Tang; Yan-Lei Ma; Zhi-Hua Jiang; Yan-Ping Liu; Guang-Ying Chen; Yan-Hui Fu; Wei Xu (Natural Product Research, 2017)

Research trends and hotspots related to ammonia oxidation based on bibliometric analysis - Maosheng Zheng; Hui-Zhen Fu; Yuh-Shan Ho (Environmental Science and Pollution Research, 2017)

Kitamycin C, a new antimycin-type antibiotic from Streptomyces antibioticus strain 200-09 - Fan Wang; Shu-Na Fu; Yi-Xuan Bao; Yu Yang; Hui-Fang Shen; Bi-Run Lin; Guang-Xiong Zhou (Natural Product Research, 2017)

Associations of rs3740677 within GAB2 Gene with LOAD in Chinese Han Population - Jing-Yu Zheng; Hui-Fu Wang; Yu Wan; Meng-Shan Tan; Chen-Chen Tan; Lin Tan; Wei Zhang; Zhan-Jie Zheng; Ling-Li Kong; Zi-Xuan Wang; Lan Tan; Jin-Tai Yu (Molecular Neurobiology, 2017)

Anti-glomerular basement membrane glomerulonephritis with thrombotic microangiopathy: a case report - Xiao-juan Yu; Sha-sha Han; Su-xia Wang; Xiao-yu Jia; Wei-yi Guo; Zhao Cui; Feng Yu; Fu-de Zhou; Ming-hui Zhao (Immunologic Research, 2017)

Developing the science product algorithm testbed for Chinese next-generation geostationary meteorological satellites: Fengyun-4 series - Min Min; Chunqiang Wu; Chuan Li; Hui Liu; Na Xu; Xiao Wu; Lin Chen; Fu Wang; Fenglin Sun; Danyu Qin; Xi Wang; Bo Li; et al. (Journal of Meteorological Research, 2017)

A new norsesquiterpene from the roots of Polyalthia laui - Zhang-Xin Yu; Ming-Ye Zhuo; Xiao-Bao Li; Yan-Hui Fu; Guang-Ying Chen; Xiao-Ping Song; Chang-Ri Han; Xin-Ming Song; Qi-Jing Fan (Natural Product Research, 2017)

A new monoterpenoid indole alkaloid from Ochrosia elliptica - A-Hong Chen; Qing-Long Liu; Yan-Lei Ma; Zhi-Hua Jiang; Jin-Ying Tang; Yan-Ping Liu; Guang-Ying Chen; Yan-Hui Fu; Wei Xu (Natural Product Research, 2017)

Whole-exome sequencing identified compound heterozygous variants in MMKS in a Chinese pedigree with Bardet-Biedl syndrome - Zhan Qi; Ying Shen; Qian Fu; Wei Li; Wei Yang; Wenshan Xu; Ping Chu; Yaxin Zhang; Hui Wang (Science China Life Sciences, 2017)

Effects of HLA-DRB1/DQB1 Genetic Variants on Neuroimaging in Healthy, Mild Cognitive Impairment, and Alzheimer’s Disease Cohorts - Zi-Xuan Wang; Hui-Fu Wang; Lin Tan; Jinyuan Liu; Yu Wan; Fu-Rong Sun; Meng-Shan Tan; Chen-Chen Tan; Teng Jiang; Lan Tan; Jin-Tai Yu (Molecular Neurobiology, 2017)

Genetic Association of HLA Gene Variants with MRI Brain Structure in Alzheimer’s Disease - Zi-Xuan Wang; Yu Wan; Lin Tan; Jinyuan Liu; Hui-Fu Wang; Fu-Rong Sun; Meng-Shan Tan; Chen-Chen Tan; Teng Jiang; Lan Tan; Jin-Tai Yu (Molecular Neurobiology, 2017)

Soil detachment and transport under the combined action of rainfall and runoff energy on shallow overland flow - Guang-lu Li; Teng-hui Zheng; Yu Fu; Bai-qiao Li; Teng Zhang (Journal of Mountain Science, 2017)

A dramatic blood plasticity in hibernating and 14-day hindlimb unloading Daurian ground squirrels (Spermophilus dauricus) - Huan-Xin Hu; Fang-Ying Du; Wei-Wei Fu; Shan-Feng Jiang; Jin Cao; Shen-Hui Xu; Hui-Ping Wang; Hui Chang; Nandu Goswami; Yun-Fang Gao (Journal of Comparative Physiology B, 2017)

Pyrosequencing of rpoB uncovers a significant biogeographical pattern of rhizobial species in soybean rhizosphere - Xing Xing Zhang; Hui Juan Guo; Jian Jiao; Pan Zhang; Hui Yang Xiong; Wen Xin Chen; Chang Fu Tian (Journal of Biogeography, 2017)
Aim Most culture‐independent studies of bacterial biogeography have been at genus or higher taxonomic levels, although many important processes mediated by bacteria are at the strain or species level, such as the competitive nodulation of rhizobia on legumes. Here, at the intra‐species level, we characterized the structural variation in rhizobial populations in soybean rhizosphere under field conditions across 32 sampling sites in three eco‐regions. Location North‐east (Heilongjiang), north (Hebei–Shandong) and south (Jiangxi) China. Methods The intra‐species diversity of rhizobia in soybean rhizospheres was investigated by rpoB pyrosequencing. Soybean nodule isolates were characterized using repetitive extragenic palindromic PCR , restriction fragment length polymorphism of 16S‐23S intergenic sequences and rpoB PCR sequencing. Patterns and processes of biogeography of identified rhizobia were studied. Results Significant biogeographical patterns of rhizosphere rhizobia at the species level were found, and the abundant species in the rhizosphere were generally the dominant microsymbionts in soybean nodules. The distribution of rhizobial species in the rhizosphere across eco‐regions correlated with combined effects of spatial, vegetative, edaphic and climatic variables. Gene flow and genetic differentiation analyses revealed that there was no dispersal limitation among geographical populations of the same rhizobial species, and drift or subsequent diversification might be involved in shaping the biogeographical pattern in addition to environmental factors. Main conclusions These results constitute the first report of the existence of rhizobial biogeography in legume rhizospheres at the species level, contrasting with most studies, which focused on nodule isolates. The method developed in this study could be used to uncover, at high resolution, the diversity of local rhizobial populations in soils. This information is crucial for choosing suitable strains or species as inoculants for a specific legume host under local field conditions. Moreover, a similar strategy could be used to study other bacteria with important ecological functions.

Combined iron and magnesium isotope geochemistry of pyroxenite xenoliths from Hannuoba, North China Craton: implications for mantle metasomatism - Xin Miao Zhao; Hui Hui Cao; Xue Mi; Noreen J. Evans; Yu Han Qi; Fang Huang; Hong Fu Zhang (Contributions to Mineralogy and Petrology, 2017)

Tissue-Specific Regulation of the Contents and Correlations of Mineral Elements in Hens by Zinc Oxide Nanoparticles - Yong Zhao; Yan-Ni Feng; Lan Li; Hong-Fu Zhang; Yu-Na Zhang; Peng-Fei Zhang; Xin-Qi Liu; Wei-Dong Zhang; Ting-Ting Huang; Li Zhao; Wei Shen; Zhi-Hui Hao (Biological Trace Element Research, 2017)

Offshore detachment of the Changjiang River plume and its ecological impacts in summer - Qinsheng Wei; Zhigang Yu; Baodong Wang; Hui Wu; Junchuan Sun; Xuelei Zhang; Mingzhu Fu; Changshui Xia; Huiwu Wang (Journal of Oceanography, 2017)

Biomass Yield and Nutrient Uptake of Energy Sorghum in Response to Nitrogen Fertilizer Rate on Marginal Land in a Semi-Arid Region - Asif Ameen; Xiaolin Yang; Feng Chen; Chaochen Tang; Fu Du; Shah Fahad; Guang Hui Xie (BioEnergy Research, 2017)