Technological development pathway for carbon neutrality in China - Siyue Guo; Yu Liu; Weichen Zhao; Jiaquan Li; Guangwen Hu; Hui Kong; Yifan Gu; Bang Xu; Xiaodan Huang; Yan Zheng; Shihan Zhang; Da Zhang; et al. (Science Bulletin, 2023)

Topology regulation of nanomedicine for autophagy-augmented ferroptosis and cancer immunotherapy - Ruizhi Hu; Chen Dai; Xinyue Dai; Caihong Dong; Hui Huang; Xinran Song; Wei Feng; Li Ding; Yu Chen; Bo Zhang (Science Bulletin, 2023)

A repeated dose 28-day oral toxicity study of sodium dehydroacetate (DHA-S) in Wistar rats - Hong-ju Du; Guo-hui Tong; Jun-yu Ning; Shan Gao; Qing Yang; Ying Feng; Peng Zhang; Wei Zhang; Hai-ming Jing; Guo-jun Li (Regulatory Toxicology and Pharmacology, 2023)

The impact of piston and sloshing motions on added resistance from moonpool configurations - Jia-Yu Sun; Shi-Li Sun; Shu-Zheng Sun; Hui-Long Ren (Ocean Engineering, 2023)

Extract of Ginkgo biloba leaves attenuates neurotoxic damages in rats and SH-SY5Y cells exposed to a high level of fluoride - Jie Xiang; Yan-Lin Ma; Jian Zou; Xiao-Xiao Zeng; Xiao Xiao; Yan-Long Yu; Yang-Ting Dong; Long-Yan Ran; Xiao-Lan Qi; Wei Hong; Yan-Hui Gao; Zhi-Zhong Guan (Journal of Trace Elements in Medicine and Biology, 2023)

Reduction of miR-133a-3p contributes to apoptosis and gasdermin E-mediated pyroptosis of keratinocytes in skin exposed to ultraviolet B radiation - Changjun Song; Wenlan Zhang; Ta Xiao; Min Li; Yiqun Zhang; Xuecui Wei; Yujie Chen; Ni Lian; Yangying Ke; Hui Yu; Min Li; Heng Gu; et al. (Journal of Photochemistry and Photobiology B: Biology, 2023)

Electron-transfer-based peroxymonosulfate activation on defect-rich carbon nanotubes: Understanding the substituent effect on the selective oxidation of phenols - Shuiping Yu; Yanhua Peng; Penghui Shao; Yuanyue Wang; Youwen He; Wei Ren; Liming Yang; Hui Shi; Xubiao Luo (Journal of Hazardous Materials, 2023)

Effect of soil pH on thermally enhanced desorption of m-xylene by zero-valent iron particles under an electromagnetic field - Kai Yu; Xiuqiong Yang; Mao Wan; Haowen Jiang; Penghui Shao; Liming Yang; Hui Shi; Xubiao Luo (Journal of Hazardous Materials, 2023)

Degradation of poly(butylene adipate-co-terephthalate) films by Thermobifida fusca FXJ-1 isolated from compost - Xianbo Jia; Ke Zhao; Jie Zhao; Chenqiang Lin; Hui Zhang; Longjun Chen; Jichen Chen; Yu Fang (Journal of Hazardous Materials, 2023)

Enhancing the spatial separation of photogenerated charges on Fe-based MOFs via structural regulation for highly-efficient photocatalytic Cr(VI) reduction - Hao Zhang; Yu-Hui Luo; Feng-Yu Chen; Wu-Yue Geng; Xin-Xin Lu; Dong-En Zhang (Journal of Hazardous Materials, 2023)

Resource utilization of bovine bone to prepare biochar as persulfate activator for phenol degradation - Mingze Sun; Jianhua Qu; Tianyi Han; Jiaqi Xue; Kaige Li; Zhao Jiang; Guangshan Zhang; Hui Yu; Ying Zhang (Journal of Cleaner Production, 2023)

Effect of gradual increase of atmospheric CO2 concentration on nitrification potential and communities of ammonia oxidizers in paddy fields - Bing-jie Ren; Li-dong Shen; Xin Liu; Jing-hao Jin; He-chen Huang; Mao-hui Tian; Yu-ling Yang; Wang-ting Yang; Jia-qi Liu; Cai-yu Geng; Hong-sheng Wu; Zheng-hua Hu (Journal of Environmental Management, 2023)

Habitat quality dynamics in China's first group of national parks in recent four decades: Evidence from land use and land cover changes - Xin Chen; Le Yu; Yue Cao; Yidi Xu; Zhicong Zhao; Youbo Zhuang; Xuehua Liu; Zhenrong Du; Tao Liu; Bo Yang; Lu He; Hui Wu; et al. (Journal of Environmental Management, 2023)

Early Paleozoic collision-related structures in the Tarim Craton, NW China: Implications for the Proto-Tethys evolution - Yue-Jun Li; Yong-Jin Gao; Hui Zhou; Guang-Ya Zhang; Lei Wen; Yan Zhao; Cheng Li; Duo-Ming Zheng; Ya-Lei Liu; Hong-Hui Li; Cai-Ming Luo; Tong-Fei Huang; et al. (Journal of Asian Earth Sciences, 2023)

Marked shifts of harmful algal blooms in the Bohai Sea linked with combined impacts of environmental changes - Xiao-Yu Li; Ren-Cheng Yu; Anthony J. Richardson; Chaojiao Sun; Ruth Eriksen; Fan-Zhou Kong; Zheng-Xi Zhou; Hui-Xia Geng; Qing-Chun Zhang; Ming-Jiang Zhou (Harmful Algae, 2023)

Effect of solvent swelling with different enhancement methods on the microstructure and pyrolysis performance of Hefeng subbituminous coal - Hui Kan; Yue Wang; Wen-Long Mo; Xian-Yong Wei; Hong-Yu Mi; Kong-Jun Ma; Mei-Xia Zhu; Wen-Cang Guo; Jia Guo; Jun-Min Niu; Xing Fan (Fuel, 2023)

Precipitation/dissolution equilibrium to achieve trace iron doping on the surface of β-Ni(OH)2 for electrocatalytic oxygen evolution - Hui-Ying Zhao; Ruo-Yao Fan; Zi-Yi Zhao; Xin-Yu Zhang; Bin Dong; Qian-Xi Lv; Xin Liu; Bin Liu; Yong-Ming Chai (Fuel, 2023)

Oxidation affects dye binding of myofibrillar proteins via alteration in net charges mediated by a reduction in isoelectric point - Qingqing Yu; Tong Shi; Zhiyu Xiong; Li Yuan; Hui Hong; Ruichang Gao; Yulong Bao (Food Research International, 2023)

Region, vintage, and grape maturity co-shaped the ionomic signatures of the Cabernet Sauvignon wines - Xiao Han; Hao-Cheng Lu; Yu Wang; Xiao-Tong Gao; Hui-Qing Li; Meng-Bo Tian; Ning Shi; Ming-Yu Li; Xiao-Li Yang; Fei He; Chang-Qing Duan; Jun Wang (Food Research International, 2023)

Transcriptome and metabolome reveal the effects of three canopy types on the flavonoids and phenolic acids in ‘Merlot’ (Vitis vinifera L.) berry pericarp - Shou-An Han; Hui Xie; Min Wang; Jun-Gao Zhang; Yu-Hui Xu; Xue-Hui Zhu; Aiermaike Caikasimu; Xue-Wei Zhou; Si-Le Mai; Ming-Qi Pan; Wen Zhang (Food Research International, 2023)

Enhanced stability and combustion performance of AlH3 in combination with commonly used oxidizers - Ming-Hui Yu; Su-Lan Yang; Wu-Xi Xie; Zhao-Yang Zhu; He-Ping Li; Qi-Long Yan (Fuel, 2023)

Pickering water in oil emulsions prepared from biocompatible gliadin/ethyl cellulose complex particles - Fu-Zhen Zhou; Xin-Hao Yu; Dong-Hui Luo; Xiao-Quan Yang; Shou-Wei Yin (Food Hydrocolloids, 2023)

Neurotoxicity of mycotoxin citrinin: Novel evidence in developing zebrafish and underlying mechanisms in human neuron cells - Jui-Feng Tsai; Ting-Shuan Wu; Feng-Yih Yu; Biing-Hui Liu (Food and Chemical Toxicology, 2023)

Microplastics existence intensified bloom of antibiotic resistance in livestock feces transformed by black soldier fly - Zhimin Xu; Xinyue Wu; Jiexiang Zhang; Ping Cheng; Zhihao Xu; Weimin Sun; Yuming Zhong; Yifan Wang; Guohui Yu; Hui Liu (Environmental Pollution, 2023)

Dydrogesterone disrupts lipid metabolism in zebrafish brain: A study based on metabolomics and Fourier transform infrared spectroscopy - Yu-Xia Jiang; Wen-Jun Shi; Li-Xin Hu; Dong-Dong Ma; Hui Zhang; Choon Nam Ong; Guang-Guo Ying (Environmental Pollution, 2023)

Analysis of the spatiotemporal patterns and decoupling effects of China's water resource spatial equilibrium - Dehui Bian; Xiaohua Yang; Yu Lu; Hui Chen; Boyang Sun; Feifei Wu; Yajing Chen; Weiqi Xiang (Environmental Research, 2023)

Residential greenness and risk of incident dementia: A prospective study of 375,342 participants - He-Ying Hu; Ya-Hui Ma; Yue-Ting Deng; Ya-Nan Ou; Wei Cheng; Jian-Feng Feng; Lan Tan; Jin-Tai Yu (Environmental Research, 2023)

The associations of particulate matter short-term exposure and serum lipids are modified by vitamin D status: A panel study of young healthy adults - Jia-Min Li; Han-Yu Yang; Si-Han Wu; Shyamali C. Dharmage; Bin Jalaludin; Luke D. Knibbs; Michael S. Bloom; Yuming Guo; Lidia Morawska; Joachim Heinrich; Yim Steve Hung Lam; Li-Zi Lin; et al. (Environmental Pollution, 2023)

Association between long-term ambient ozone exposure and attention-deficit/hyperactivity disorder symptoms among Chinese children - Peien Zhou; Wangjian Zhang; Yu-Jie Xu; Ru-Qing Liu; Zhengmin Qian; Stephen Edward McMillin; Elizabeth Bingheim; Li-Zi Lin; Xiao-Wen Zeng; Bo-Yi Yang; Li-Wen Hu; Wen Chen; et al. (Environmental Research, 2023)

The association between long-term ambient fine particulate exposure and the mortality among adult patients initiating dialysis: A retrospective population-based cohort study in Taiwan - Shih-Feng Chen; Yu-Hui Chien; Pau-Chung Chen (Environmental Pollution, 2023)

Identification of serum metabolic signatures of environmental-leveled phthalate in the Taiwanese child population using NMR-based metabolomics - Sheng-Han Lee; Zhi-Yi Du; Wei-Chen Tseng; Wan-Yu Lin; Mei-Huei Chen; Ching-Chun Lin; Hao-Jan Liang; Hui-Ju Wen; Yue-Leon Guo; Pau-Chung Chen; Ching-Yu Lin (Environmental Pollution, 2023)

Experimental and numerical study of steel wire mesh reinforced G-HPC slab protected by UHMWPE FRC under multiple blast loadings - Pengcheng Yuan; Hui Xiang; Shenchun Xu; Jian Liu; Yu Su; Kefo Qu; Chengqing Wu (Engineering Structures, 2023)

Poly(caffeic acid) as interlayer to enhance nanofiltration performance of polyamide composite membrane - Xiao-lei Wang; Ya-xian Xue; Shu-qian Dong; Qi Wang; Jiang-tao Yu; Hui-cai Wang; Huan Zhang; Wan Wang; Jun-fu Wei (Desalination, 2023)

Dual enhancement of water oxidation catalysis by MXene in the grass-like ZnCoCH@Ti3C2Tx heterostructure - Mengshu Li; Ziquan Zeng; Weicai Liu; Hui Zong; Bo Li; Shijing Gong; Ke Yu; Ziqiang Zhu (Chemical Engineering Journal, 2023)

Recent advances in photoelectrocatalytic advanced oxidation processes: From mechanism understanding to catalyst design and actual applications - Xinyu Zhang; Wenchao Yu; Yajie Guo; Shunlin Li; Yiran Chen; Hui Wang; Zhaoyong Bian (Chemical Engineering Journal, 2023)

13.2% EQE near-infrared TADF OLED with emission peak at 761 nm - Jing-Wen Tai; Yukun Tang; Kai Zhang; Chen-Zong Yang; Ze-Hui Pan; Yu-Ching Lin; Yu-Wei Shih; Chia-Hsun Chen; Tien-Lung Chiu; Jiun-Haw Lee; Chuan-Kui Wang; Chung-Chih Wu; et al. (Chemical Engineering Journal, 2023)

Overview of preparation, modification, and application of tunicate-derived nanocellulose - Xiaoyu Lv; Jianing Han; Min Liu; Hui Yu; Kaihua Liu; Yifan Yang; Yi Sun; Panpan Pan; Zhenlin Liang; Lirong Chang; Jingdi Chen (Chemical Engineering Journal, 2023)

Reversible cross-linked phosphorylate binder for recyclable lithium-sulfur batteries - Hui Wang; Guangzhao Zhang; Yukun Chen; Peitao Zheng; Huan Yi; Yonghong Deng; Yu Yang; Chaoyang Wang (Chemical Engineering Journal, 2023)

Temperature-mediated construction of a plantar pressure-relieving, thermally insulating, and biodegradable thick-walled cellulose sponge insole - Jie Zou; Shufen Li; Zhanhong Yuan; Xianglin Pei; Hui Yu; Pan Chen; Dongdong Ye (Chemical Engineering Journal, 2023)

Cr(VI) adsorption and reduction by magnetite-humic acid adsorption complexes under mildly acidic conditions: Synergistic/antagonistic mechanism and multi-step reaction model - Jingjie Chang; Jia Zhang; Hui Wang; Yunfei Bai; Yu Liu; Yanze Bi; Huanzhen Zhang; Honghan Chen; Samuel Barnie; Haijiao Xie (Chemical Engineering Journal, 2023)

α-D-1,3-glucan from Radix Puerariae thomsonii improves NAFLD by regulating the intestinal flora and metabolites - Qiong Li; Wenjun Liu; Hua Zhang; Chong Chen; Ronghua Liu; Hengwei Hou; Quan Luo; Qinqin Yu; Hui Ouyang; Yulin Feng; Weifeng Zhu (Carbohydrate Polymers, 2023)

Hydroxychloroquine repairs burn damage through the Wnt/β-catenin pathway - Sheau-Chung Tang; Chun-Te Lu; Jiunn-Liang Ko; Cheng-Hui Lin; Yu-Ping Hsiao (Chemico-Biological Interactions, 2023)

Scalable anti-infection polyurethane catheters with long-acting and autoclavable properties - Zongpeng Xiu; Meiping Yang; Ruonan Wu; Chengyue Lei; Hui-Min Ren; Bingran Yu; Shuai Gao; Shun Duan; Dimeng Wu; Fu-Jian Xu (Chemical Engineering Journal, 2023)

Influence of degree of compaction on arsenic and antimony co-contaminated soil stabilization: Geoenvironmental properties and chemical species - Shi-Ji Zhou; Ya-Song Feng; Guang-Yu Yang; Hui-Yang Sun; Qing Zhang; Yang Hu; Yan-Jun Du (CATENA, 2023)

Spatial distribution of marine atmospheric isoprene in the Southern Hemisphere: Role of atmospheric removal capacity - Xiawei Yu; Yanli Zhang; Ruilin Jin; Zhangyan Chai; Qihou Hu; Juan Yu; Jie Xing; Lulu Zhang; Hui Kang; Yanxu Zhang; Xinming Wang; Zhouqing Xie (Atmospheric Environment, 2023)

Genetic dissection reveals the complex architecture of amino acid composition in soybean seeds - Wenjie Yuan; Jie Huang; Haiyang Li; Yujie Ma; Chunju Gui; Fang Huang; Xianzhong Feng; Deyue Yu; Hui Wang; Guizhen Kan (Theoretical and Applied Genetics, 2023)

HvNCX, a prime candidate gene for the novel qualitative locus qS7.1 associated with salinity tolerance in barley - Juan Zhu; Hui Zhou; Yun Fan; Yu Guo; Mengna Zhang; Sergey Shabala; Chenchen Zhao; Chao Lv; Baojian Guo; Feifei Wang; Meixue Zhou; Rugen Xu (Theoretical and Applied Genetics, 2023)
Key Message A major QTL (qS7.1) for salinity damage score and Na+ exclusion was identified on chromosome 7H from a barley population derived from a cross between a cultivated variety and a wild accession. qS7.1 was fine-mapped to a 2.46 Mb physical interval and HvNCX encoding a sodium/calcium exchanger is most likely the candidate gene. Abstract Soil salinity is one of the major abiotic stresses affecting crop yield. Developing salinity-tolerant varieties is critical for minimizing economic penalties caused by salinity and providing solutions for global food security. Many genes/QTL for salt tolerance have been reported in barley, but only a few of them have been cloned. In this study, a total of 163 doubled haploid lines from a cross between a cultivated barley variety Franklin and a wild barley accession TAM407227 were used to map QTL for salinity tolerance. Four significant QTL were identified for salinity damage scores. One ( qS2.1 ) was located on 2H, determining 7.5% of the phenotypic variation. Two ( qS5.1 and qS5.2 ) were located on 5H, determining 5.3–11.7% of the phenotypic variation. The most significant QTL was found on 7H, explaining 27.8% of the phenotypic variation. Two QTL for Na + content in leaves under salinity stress were detected on chromosomes 1H ( qNa1.1 ) and 7H( qNa7.1 ). qS7.1 was fine-mapped to a 2.46 Mb physical interval using F 4 recombinant inbred lines. This region contains 23 high-confidence genes, with HvNCX which encodes a sodium/calcium exchanger being most likely the candidate gene. HvNCX was highly induced by salinity stress and showed a greater expression level in the sensitive parent. Multiple nucleotide substitutions and deletions/insertions in the promoter sequence of HvNCX were found between the two parents. cDNA sequencing of the HvNCX revealed that the difference between the two parents is conferred by a single Ala77/Pro77 amino acid substitution, which is located on the transmembrane domain. These findings open new prospects for improving salinity tolerance in barley by targeting a previously unexplored trait.

Combining Bone Collagen Matrix with hUC-MSCs for Application to Alveolar Process Cleft in a Rabbit Model - Xue-Cheng Sun; Hu Wang; Dan Zhang; Jian-Hui Li; Li-Qiang Yin; Yu-Fang Yan; Xu Ma; Hong-Fei Xia (Stem Cell Reviews and Reports, 2023)

mTORC1-Dependent and GSDMD-Mediated Pyroptosis in Developmental Sevoflurane Neurotoxicity - Wang Wen-Yuan; Yi Wan-Qing; Hu Qi-Yun; Liu Yu-Si; Qian Shao-Jie; Liu Jin-Tao; Mao Hui; Cai Fang; Yang Hui-Ling (Molecular Neurobiology, 2023)

Correction to: Ketone Body Rescued Seizure Behavior of LRP1 Deficiency in Drosophila by Modulating Glutamate Transport - Jin-Ming Zhang; Ming-Jie Chen; Jiong-Hui He; Ya-Ping Li; Zhi-Cai Li; Zi-Jing Ye; Yong-Hui Bao; Bing-Jun Huang; Wen-Jie Zhang; Ping Kwan; Yu-Ling Mao; Jing-da Qiao (Journal of Molecular Neuroscience, 2023)

Review and prospects of mining chemical dust suppressant: classification and mechanisms - Hui Dong; Haiming Yu; Rongxiao Xu; Weimin Cheng; Yuxi Ye; Sen Xie; Junwei Zhao; Yu Cheng (Environmental Science and Pollution Research, 2023)

Gas-phase and PM2.5-bound phthalates in nail salons: characteristics, exposure via inhalation, and influencing factors - Chia-Ling Chang; Hui-Tzu Chen; Chung-Yu Chen; En-Yu Chen; Kuan-Ting Lin; Chien-Cheng Jung (Environmental Science and Pollution Research, 2023)

Effects of land clearing for agriculture on soil organic carbon stocks in drylands: A meta‐analysis - Yuangang Wang; Geping Luo; Chaofan Li; Hui Ye; Haiyang Shi; Binbin Fan; Wenqiang Zhang; Chen Zhang; Mingjuan Xie; Yu Zhang (Global Change Biology, 2023)
Agricultural activities have been expanding globally with the pressure to provide food security to the earth's growing population. These agricultural activities have profoundly impacted soil organic carbon (SOC) stocks in global drylands. However, the effects of clearing natural ecosystems for cropland (CNEC) on SOC are uncertain. To improve our understanding of carbon emissions and sequestration under different land uses, it is necessary to characterize the response patterns of SOC stocks to different types of CNEC. We conducted a meta‐analysis with mixed‐effect model based on 873 paired observations of SOC in croplands and adjacent natural ecosystems from 159 individual studies in global drylands. Our results indicate that CNEC significantly ( p p −1 ). The results derived from our meta‐analysis could be used for refining the estimation of dryland carbon dynamics and developing SOC sequestration strategies to achieve the removal of CO 2 from the atmosphere.

The signal-to-cutoff ratios to predict HCV infection among people who inject drugs - Bing Chen; Ling-yu Gao; Zhong-hui Ma; Hao Chang; Li-jian Pei; Qiang Zhou; Wen-ge Xing (VirusDisease, 2022)

Mesenchymal Stem Cell Secreted-Extracellular Vesicles are Involved in Chondrocyte Production and Reduce Adipogenesis during Stem Cell Differentiation - Yu-Chen Tsai; Tai-Shan Cheng; Hsiu-Jung Liao; Ming-Hsi Chuang; Hui-Ting Chen; Chun-Hung Chen; Kai-Ling Zhang; Chih-Hung Chang; Po-Cheng Lin; Chi-Ying F. Huang (Tissue Engineering and Regenerative Medicine, 2022)
Background: Extracellular vesicles (EVs) are derived from internal cellular compartments, and have potential as a diagnostic and therapeutic tool in degenerative disease associated with aging. Mesenchymal stem cells (MSCs) have become a promising tool for functional EVs production. This study investigated the efficacy of EVs and its effect on differentiation capacity. Methods: The characteristics of MSCs were evaluated by flow cytometry and stem cell differentiation analysis, and a production mode of functional EVs was scaled from MSCs. The concentration and size of EVs were quantitated by Nanoparticle Tracking Analysis (NTA). Western blot analysis was used to assess the protein expression of exosome-specific markers. The effects of MSC-derived EVs were assessed by chondrogenic and adipogenic differentiation analyses and histological observation. Results: The range of the particle size of adipose-derived stem cells (ADSCs)- and Wharton’s jelly -MSCs-derived EVs were from 130 to 150 nm as measured by NTA, which showed positive expression of exosomal markers. The chondrogenic induction ability was weakened in the absence of EVs in vitro . Interestingly, after EV administration, type II collagen, a major component in the cartilage extracellular matrix, was upregulated compared to the EV-free condition. Moreover, EVs decreased the lipid accumulation rate during adipogenic induction. Conclusion: The results indicated that the production model could facilitate production of effective EVs and further demonstrated the role of MSC-derived EVs in cell differentiation. MSC-derived EVs could be successfully used in cell-free therapy to guide chondrogenic differentiation of ADSC for future clinical applications in cartilage regeneration.

Causal gene identification and desirable trait recreation in goldfish - Peng Yu; Yang Wang; Zhi Li; Hui Jin; Liang-Liang Li; Xiao Han; Zhong-Wei Wang; Xiao-Li Yang; Xi-Yin Li; Xiao-Juan Zhang; Li Zhou; Jian-Fang Gui (Science China Life Sciences, 2022)

The landscape of aging - Yusheng Cai; Wei Song; Jiaming Li; Ying Jing; Chuqian Liang; Liyuan Zhang; Xia Zhang; Wenhui Zhang; Beibei Liu; Yongpan An; Jingyi Li; Baixue Tang; et al. (Science China Life Sciences, 2022)

Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor - Xiaoxing Huang; Youwang Wang; Cong Yu; Hui Zhang; Qiang Ru; Xinxin Li; Kai Song; Min Zhou; Ping Zhu (Science China Life Sciences, 2022)

Plastid diversity and chromoplast biogenesis in differently coloured carrots: role of the DcOR3Leu gene - Yu-Min Zhang; Rong-Hua Wu; Lu Wang; Ya-Hui Wang; Hui Liu; Ai-Sheng Xiong; Zhi-Sheng Xu (Planta, 2022)

Shanghai Autism Early Development: An Integrative Chinese ASD Cohort - Yuan Dai; Yuqi Liu; Lingli Zhang; Tai Ren; Hui Wang; Juehua Yu; Xin Liu; Zilin Chen; Lin Deng; Minyi Tao; Hangyu Tan; Chu-Chung Huang; et al. (Neuroscience Bulletin, 2022)

Transcranial Direct-Current Stimulation Regulates MCT1-PPA-PTEN-LONP1 Signaling to Confer Neuroprotection After Rat Cerebral Ischemia–Reperfusion Injury - Xiangyi Kong; Wenjie Hu; Yu Cui; Jingchen Gao; Xujin Yao; Jinyang Ren; Tao Lin; Jiangdong Sun; Yunyi Gao; Xiaohua Li; Hui Wang; Huanting Li; et al. (Molecular Neurobiology, 2022)
Propionic acid (PPA) is a critical metabolite involved in microbial fermentation, which functions to reduce fat production, inhibit inflammation, and reduce serum cholesterol levels. The role of PPA in the context of cerebral ischemia–reperfusion (I/R) injury has yet to be clarified. Increasing evidence indicate that transcranial direct-current stimulation (tDCS) is a safe approach that confers neuroprotection in cerebral ischemia injury. Here, we show that the levels of PPA were reduced in the ischemic brain following a rat cerebral I/R injury and in the cultured rat cortical neurons after oxygen–glucose deprivation (OGD), an in vitro model of ischemic injury. We found that the decreased levels of transporter protein monocarboxylate transporter-1 (MCT1) were responsible for the OGD-induced reduction of PPA. Supplementing PPA reduced ischemia-induced neuronal death after I/R. Moreover, our results revealed that the neuroprotective effect of PPA is mediated through downregulation of phosphatase PTEN and subsequent upregulation of Lon protease 1 (LONP1). We demonstrated that direct-current stimulation (DCS) increased MCT1 expression and PPA level in OGD-insulted neurons, while tDCS decreased the brain infarct volume in the MCAO rats via increasing the levels of MCT1 expression and PPA. This study supports a potential application of tDCS in ischemic stroke.

Differential bone metabolism and protein expression in mice fed a high-fat diet versus Daurian ground squirrels following natural pre-hibernation fattening - Xuli Gao; Shenyang Shen; Qiaohua Niu; Weilan Miao; Yuting Han; Ziwei Hao; Ning An; Yingyu Yang; Yu Zhang; Han Zhang; Kenneth B. Storey; Hui Chang (Journal of Zhejiang University-SCIENCE B, 2022)

Construction of A375·S2 Melanoma Cell Line with High Sensibility to IL-1 by Overexpressing IL-1 Receptor - Yong-Fei Zhou; Wei-Xiao Wang; Jiao-Jiao Nie; Dan-Ying Zhao; Lu Yu; Jun-Liang Chang; Jing-Hui Liu; Yu-Feng Cao (Indian Journal of Microbiology, 2022)

An association study on the risk, glucocorticoids effectiveness, and prognosis of systemic lupus erythematosus: insight from mitochondrial DNA copy number - Zhen Li; Qi-Qun Zong; Chun-Xia Zhai; Guang-Hui Yu; Wan-Qin Hu; Yu-Hua Wang; Lin-Lin Wang; Zi-Ye Yan; Ting-Yu Zhang; Ying Teng; Shuang Liu; Jing Cai; et al. (Immunologic Research, 2022)

Low-Level Environmental Per- and Polyfluoroalkyl Substances and Preterm Birth: A Nested Case–Control Study Among a Uyghur Population in Northwestern China - Bo-Yi Yang; Jianhua Wu; Xilong Niu; Chuanjiang He; Michael S. Bloom; Maihefuzaimu Abudoukade; Mairiyemu Abulizi; Aimin Xu; Beibei Li; Li Li; Xuemei Zhong; Qi-Zhen Wu; et al. (Exposure and Health, 2022)

The Pseudogene BMEA_B0173 Deficiency in Brucella melitensis Contributes to M-epitope Formation and Potentiates Virulence in a Mice Infection Model - Ge Zhang; Hao Dong; Yu Feng; Hui Jiang; Tonglei Wu; Jiali Sun; Xin Wang; Minghe Liu; Xiaowei Peng; Yinghui Zhang; Xiaoqian Zhang; Liangquan Zhu; et al. (Current Microbiology, 2022)

A Review on the Water Quality Criteria of Nonylphenol and the Methodological Construction for Reproduction Toxicity Endocrine Disrupting Chemicals - Yajun Hong; Hui Li; Chenglian Feng; Daqing Liu; Zhenfei Yan; Yu Qiao; Yingchen Bai; Fengchang Wu (Reviews of Environmental Contamination and Toxicology, 2022)

Study of the biological characteristics of human umbilical cord mesenchymal stem cells after long-time cryopreservation - Mingqi Zhang; Yan Zhao; Le Wang; Yuqiang Zheng; Hui Yu; Xiaoming Dong; Wei He; Zhengqin Yin; Zhuoshi Wang (Cell and Tissue Banking, 2022)
Human umbilical cord mesenchymal stem cells (hUC-MSCs) have considerable potential in cell therapy. Cryopreservation represents the gold standard in cell storage, but its effect on hUC-MSCs is still not well understood. The aim of this study was to investigate the effect of one year of cryopreservation and thawing on the biological characteristics of hUC-MSCs from the same donors. Fresh hUC-MSCs were cryopreserved in commercial freezing medium (serum-free CellBanker 2) at passage 2. After one year of cryopreservation, the hUC-MSCs were thawed and subcultured to passage 4. The comparison was performed in terms of followings: cell count, viability, morphology, proliferation capacity, differentiation potential and chromosomal stability. The total cell count and viability of hUC-MSCs before and after one year of cryopreservation were 1 × 10 7 and 96.34% and 0.943 × 10 7 and 93.81%, respectively. Cryopreserved and fresh hUC-MSCs displayed a similar cell doubling times, expressed the markers CD73, CD90, CD105 and were negative for the markers CD34, CD45, and HLA-DR. Karyotypes were found to be normal after one year of cryopreservation. The trilineage differentiation properties were maintained after cryopreservation. However, when compared to freshly isolated hUC-MSCs from the same donor, cryopreserved hUC-MSCs exhibited decreased expression of osteogenesis- and chondrogenesis-related genes including Runx2, Sox9, and Col1a1, and increased expression of adipogenesis-related genes. These results demonstrated that cryopreservation did not affect cell morphology, surface marker expression, cell viability, proliferative capacity, or chromosomal stability. However, the osteogenic and chondrogenic differentiation capacities of cryopreserved hUC-MSCs were slightly reduced compared with those of fresh cells from the same donor. Graphical abstract

Immunogenicity and protective efficacy of a DNA vaccine inducing optimal expression of the SARS-CoV-2 S gene in hACE2 mice - Zhuo-xin Li; Sheng Feng; He Zhang; Xin-yu Zhuang; Chao Shang; Shi-yu Sun; Ji-cheng Han; Yu-biao Xie; Jin-yong Zhang; Wei Wang; Cheng-hui Li; Guan-yu Zhao; et al. (Archives of Virology, 2022)

Amino Acid Composition, Antioxidant, α-Glucosidase and α-Amylase Inhibitory Activities of the Enzymic Polypeptide from Acer truncatum Seed Meal - Liang Wei; Hui Li; Xinxin Yu; Huiying Yang; Duowen Pu; Minghua Zhu; Qi Lu; Yihong Bao; Yuangang Zu (International Journal of Peptide Research and Therapeutics, 2022)

Synergistic removal of organic pollutants from water by CTF/BiVO4 heterojunction photocatalysts - Yan Yu; Yanan Sun; Beixiao Ge; Jiawen Yan; Kaili Zhang; Hui Chen; Jinxing Hu; Juntao Tang; Shuang Song; Tao Zeng (Environmental Science and Pollution Research, 2022)

Clustering of large‐scale circulation patterns during tropical cyclone preformation period using self‐organizing maps - Zi‐Qing Wang; Guang‐Hua Chen; Yu‐Hui Zhao (International Journal of Climatology, 2022)
Based on self‐organizing maps (SOM), clustering analysis is performed on the lower‐level large‐scale flow fields centred at the tropical cyclone (TC) genesis points averaged over the 24‐hr TC preformation period. A total of 461 TCs over the western North Pacific (WNP) from June to November in 2000–2019 are classified into five patterns, that is, convergence (CON) pattern, monsoon trough (MT) pattern, pre‐existing cyclone (PC) pattern, subtropical high (SH) pattern and easterly wave (EW) pattern. The most frequent and southmost pattern, the CON pattern, is characterized by a confluent zone of monsoonal southwesterly flows and easterly flows. The second dominant pattern, the MT pattern, occurs the westmost and has a larger cyclonic vorticity in the strongest monsoon trough among the five patterns. In contrast, cyclogenesis in the SH pattern is featured by both the confluent zone and the cyclonic wind shear largely attributed to the subtropical high. The PC pattern features a pre‐existing cyclone to the northwest. The EW pattern with easterly flows in all four adjacent quadrants has the smallest number of TC formation and relatively northeast genesis location. Statistics also shows that the CON pattern dominates in late season, while the other four mainly appear in summertime. Large‐scale environmental conditions are quantified and comparisons with previous studies are also discussed.

Mulberry leaf extract improves non-specific immunity and antioxidant capacity of largemouth bass (Micropterus salmoides) fed a high-starch diet - Jing Tingsen; Luo Hui; Huang Junwa; Li Zhe; Li Yu; Jin Honghao; Zou Xinxi; Ke Zhenlin; Sun Wenbo; Hou Mengdan; Yang Huijun; Ye Hua (Frontiers in Marine Science, 2022)
A 70-day experiment was conducted to investigate the effects of mulberry leaf extract (MLE) on growth, proximate compositions, antioxidant and plasma biochemical parameters, and indices of non-specific immunity of largemouth bass ( Micropterus salmoides ) fed a high-starch diet. Two hundred eighty largemouth bass (initial body weight, 68.00 ± 0.19 g) were randomly fed seven diets: basal-starch diet (BSD; 8.88% starch), high-starch diet (HSD; 11.42% starch), and HSD diets supplemented with 0.05%, 0.10%, 0.20%, 0.50%, and 1.00% MLE (MLE1, MLE2, MLE3, MLE4, and MLE5, respectively). The results indicated that HSD and MLE did not significantly affect the growth performance of largemouth bass during the experimental period compared with that of the BSD, but the supplementation with more than 0.20% (MLE3, MLE4, and MLE5) MLE significantly decreased the hepatosomatic index (HSI) values, and 1.00% (MLE5) MLE significantly decreased the viscerosomatic index (VSI) values. The whole-body moisture of fish fed an HSD decreased significantly, while the whole-body lipid content increased significantly in the HSD group compared with the BSD group. Compared with HSD, MLE supplementation significantly decreased the moisture and lipid contents in the whole body. Supplementation with more than 0.20% MLE (MLE3, MLE4, and MLE5) significantly decreased the moisture content in the muscle. Supplementation with 1.00% MLE significantly decreased the content of hepatic and muscle glycogen. The malondialdehyde (MDA) content of the HSD group was significantly increased compared to that of the BSD group, whereas more than 0.10% (MLE2, MLE3, MLE4, and MLE5) MLE significantly decreased the MDA content. Additionally, the total antioxidant capacity (T-AOC), catalase (CAT), and glutathione peroxidase (GSH-Px) activities of MLE5 were significantly higher than those of the HSD group. The complement-3 (C3) content and globulin (GLB) in the plasma of the HSD group were significantly lower than those of the BSD group. Plasma C3 levels in the MLE3, MLE4, and MLE5 groups were significantly higher than those in the HSD group. In addition, glucose (GLU) levels in the MLE3, MLE4, and MLE5 groups were significantly lower than those in the HSD group. Supplementation with 0.50% (MLE4) MLE significantly increased the lysozyme (LYZ) content and decreased the activities of alanine transaminase (ALT) and aspartate transaminase (AST). Supplementation with 1.00% MLE significantly increased complement-4 (C4) and GLB contents and alkaline phosphatase (ALP) activity. Overall, these findings suggest that MLE could improve antioxidant capacity, immune function, and glycolipid metabolism, thereby alleviating the negative effects of a high-starch diet in M. salmoides .

Regulation of enzymatic and non-enzymatic antioxidants in rice seedlings against chromium stress through sodium hydrosulfide and sodium nitroprusside - Yu-Juan Lin; Xing-Hui Feng; Yu-Xi Feng (Environmental Science and Pollution Research, 2022)

Protective effect of ginsenoside Rd on military aviation noise-induced cochlear hair cell damage in guinea pigs - Xue-min Chen; Yu-hui Liu; Shuai-fei Ji; Xin-miao Xue; Lin-lin Wang; Min Zhang; Yao-ming Chang; Xiao-cheng Wang (Environmental Science and Pollution Research, 2022)

Ginsenoside Rb1 inhibits oxidative stress-induced ovarian granulosa cell injury through Akt-FoxO1 interaction - Ping Zhou; Feng Deng; Zi Yang; Canhui Cao; Hongcui Zhao; Fenting Liu; Ke Zhong; Lin Fu; Tianliu Peng; Di Sun; Hui Liu; Rong Li; et al. (Science China Life Sciences, 2022)

Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression - Qin Jin; Xiaoyu Yang; Shixue Gou; Xiaoyi Liu; Zhenpeng Zhuang; Yanhui Liang; Hui Shi; Jiayuan Huang; Han Wu; Yu Zhao; Zhen Ouyang; Quanjun Zhang; et al. (Science China Life Sciences, 2022)

Ancient DNA from Tubo Kingdom-related tombs in northeastern Tibetan Plateau revealed their genetic affinity to both Tibeto-Burman and Altaic populations - Xue-Er Yu; Chang Sun; Ye-Tao Zou; Ji-Yuan Li; Xiaoyan Ren; Hui Li (Molecular Genetics and Genomics, 2022)

A critical review on adsorption and recovery of fluoride from wastewater by metal-based adsorbents - Chenquan Ni; Chang Liu; Yu Xie; Weiqi Xie; Zhiguo He; Hui Zhong (Environmental Science and Pollution Research, 2022)

Geographic pattern of phytoplankton community and their drivers in lakes of middle and lower reaches of Yangtze River floodplain, China - Zhe Xiao; Hua Li; Xiao-Chuang Li; Ren-Hui Li; Shou-Liang Huo; Gong-Liang Yu (Environmental Science and Pollution Research, 2022)

The association between hearing threshold and urinary personal care and consumer product metabolites in middle-aged and elderly people from the USA - Yan-Peng Fu; Wen-Yu Chen; Li-Qing Guo; Ya-Qiong Zhu; Jia-Sheng Yuan; Yue-Hui Liu (Environmental Science and Pollution Research, 2022)

Investigation of Microplastics in Digestion System: Effect on Surface Microstructures and Probiotics - Hui Chen; Hongmei Chen; Shugang Nan; Hongsheng Liu; Ling Chen; Long Yu (Bulletin of Environmental Contamination and Toxicology, 2022)

A histological study of vascular wall resident stem cells in venous malformations - Hou-Fu Xia; Wen-Qiang Lai; Gao-Hong Chen; Ye Li; Qi-Hui Xie; Yu-Lin Jia; Gang Chen; Yi-Fang Zhao (Cell and Tissue Research, 2022)

Nutrient distributions and nitrogen-anomaly (N*) in the tropical North Pacific Ocean - Aiqin Han; Yu Wang; Yunlong Huo; Cai Lin; Kaiwen Zhou; Fangfang Kuang; Hui Lin (Acta Oceanologica Sinica, 2022)

A new triarylindanone and a new isobenzofuranone derivative from Selaginella tamariscina - Yu-Jie Peng; Dan Zhang; Wan-Ling Chen; Si-Yi Wang; Yao Zhang; Hui Zou; Hong-Ling Xiang; Ge-Lei Xiao (Natural Product Research, 2022)

Monoterpenoid indole alkaloids with potential neuroprotective activities from the stems and leaves of Melodinus cochinchinensis - Yu-Jie Li; Juan Li; Lan Xie; Jun-Yu Zhou; Qiu-Xuan Li; Rui-Yuan Yang; Yan-Ping Liu; Yan-Hui Fu (Natural Product Research, 2022)

Modal Identification of Structures by Eliminating the Effect of the High Ocean Wind - Chun-Xu Qu; Chang-Chong Liu; Xiao-Mei Yang; Hui-Juan Liu; Hong-Nan Li; Yu-Feng Zhang (Journal of Marine Science and Engineering, 2022)
Tropical cyclone is a rapidly rotating storm system with severe excitation such as high wind. This severe excitation may change the performance of structures, such as bridges, wharves and wind turbine structures. It is very necessary to monitor this important change. Modal parameters are the ones to reflect the structural instinct behavior. However, many identification methods assume that the excitation is white noise, which is not the truth during high ocean wind excitation. Therefore, the modal identification method to deal with severe ocean wind excitation should be investigated. This paper proposes an innovative method to eliminate the effect of high ocean wind on modal identification. The formulation to generate an impulse response is described, where the effect of high wind is pointed. Then the elimination method is derived using the wind velocity spectrum and correlation function. After the wind field is simulated, the wind velocities and spectra at all accelerometer positions are obtained. The real impulse response form is obtained. Then, modal identification using the real impulse response is performed. Finally, a practical cable-stayed bridge is employed and modal identification is performed. The results show that the identified modes can reflect structural real behavior.

Variation in the attached community structure and function of artificial habitats during ecological succession: A case study of the artificial reef area in Bailong Pearl Bay, China - Ruolin Li; Yu Guo; Ankai Zhang; Shuo Zhang; Hui Zhang; Chuanxin Qin (Frontiers in Marine Science, 2022)
With the continuous development of ports, ship transportation, resource extraction and artificial habitat deployment, an increasing number of artificial structures have created new usable spaces for marine organisms, and the biological communities living on their surfaces have undergone ecological succession. However, related studies have ignored ecological functions, interspecific relationships, and stability in different successional stages. Based on traditional taxonomy, this study applied functional diversity, niche overlap and niche breadth indexes to compare the attached organisms on artificial reefs (ARs) with different construction times in Bailong Pearl Bay, Fangchenggang City, Guangxi Zhuang Autonomous Region, China. The change trends of richness, habitat resource supply, resource utilization degree and efficiency, and interspecific relationships during the succession process were analysed. The results indicated that richness increased with functional diversity. While the number of species increased, the attached organisms showed different functional characteristics, and the number of species with identical traits decreased. The attached community in the later stage of development had a higher degree of utilization of ecological space, more comprehensive and efficient utilization of effective resources, a stronger degree of complementarity of organismal niches, and weaker interspecific competition. In the early stage of the developmental process, the attached community was affected by more environmental factors and had very significant correlations with those factors. The combination of the niche overlap index and the niche breadth index indicated that the resource supply supporting the survival and development of the attached organisms on the ARs with earlier construction times may be greater. The decrease in the number of biomarkers, the similarity of biomarkers belonging to the same family, and the similarity of dominance alternation all indicated that during the process of long-term development and community succession, the organisms attached to the various parts of the ARs tended to become more similar.

Effects of three feed attractants on the growth performance and meat quality of the largemouth bass (Micropterus salmoides) - Yuhua Yue; Mingshi Chen; Xiaoxue Bao; Yingying Yu; Wei Shi; Suksan Kumkhong; Yuhong Liu; Ying Yang; Hui Yu (Frontiers in Marine Science, 2022)
The trial was conducted to investigate the effects of limonene, allicin and betaine supplementation in low fish meal (FM) diet on growth performance, antioxidant capacity, meat quality and intestinal health in largemouth bass ( M. salmoides ). The biting-balls test and feeding trial were successively conducted. For the one, the results of the biting-ball test showed that with the increase of the concentration of the three attractants, the attracting effect firstly increased, then decreased, and the effect reached maximum at 0.2% concentration. ( P < 0.05). Further, a 9-week feeding trial was conducted using five diets, including a basal diet with 30% and 40% fish meal without attractant, 30% fish meal supplemented with 0.2% limonene, 0.2% allicin or 0.2% betaine (the diets were named FM30, FM40, FM30 + L, FM30 + A, FM30 + B, respectively). The results demonstrated that adding limonene, allicin and betaine at concentration of 0.2% to the low fish meal feed could improve final body weight, weight gain rate, and specific growth rate of M. salmoides but only in 4 weeks ( P > 0.05). Besides, dietary supplementation with attractants could significantly reduce the content of MDA in serum and liver, and increase the activity of GSH in liver ( P < 0.05). Compared with FM30 group, the supplementation with limonene, allicin or betaine diet had higher pH, redness ( a* ), yellowness ( b* ) ( P > 0.05), and lower refrigeration loss, cooking loss values ( P < 0.05). Furthermore, supplementation with attractants groups had higher values for villus height, lamina propria, crypt depth, submucous layer, and serous layer ( P < 0.05). Taken together, these results indicated that limonene, allicin and betaine had a time effect on the growth performance, and could improve antioxidant capacity, meat quality and intestinal health of M. salmoide .

Genome-wide identification and functional analysis of the peach (P. persica) laccase gene family reveal members potentially involved in endocarp lignification - Keli Qui; Hui Zhou; Haifa Pan; Yu Sheng; Hong Yu; Qingmei Xie; Hongli Chen; Yongping Cai; Jinyun Zhang; Jinling He (Trees, 2022)

Telomeres and Mitochondrial Metabolism: Implications for Cellular Senescence and Age-related Diseases - Xingyu Gao; Xiao Yu; Chang Zhang; Yiming Wang; Yanan Sun; Hui Sun; Haiying Zhang; Yingai Shi; Xu He (Stem Cell Reviews and Reports, 2022)

Lower abundance of Bacteroides and metabolic dysfunction are highly associated with the post-weaning diarrhea in piglets - Wen Ren; Bing Yu; Jie Yu; Ping Zheng; Zhiqing Huang; Junqiu Luo; Xiangbing Mao; Jun He; Hui Yan; Jinlong Wu; Daiwen Chen; Yuheng Luo (Science China Life Sciences, 2022)

Stamen and pollen development in Menispermaceae with contrasting androecium structure - Hui-Yan Zhang; Xiao-Yan Zhang; Kun Ning; Xiao-Ling Yan; Qiao-Juan Wang; Zi-Xuan Huang; Qing-Qing Zhu; Liang Zhao; Yu-Qu Zhang; Yi Ren; Xiao-Hui Zhang (Plant Systematics and Evolution, 2022)

Genetic dissection of stage-dependent dry matter accumulation in maize (Zea mays L.) kernel - Jian-ju Liu; Hui Yu; Ming Xue; Bao-shen Liu; Ming-liang Xu; Sai-hua Chen (Euphytica, 2022)

Correction to: Protective effects of fowl‑origin cadmium‑tolerant lactobacillus against sub‑chronic cadmium‑induced toxicity in chickens - Da‑Wei Chen; Hui‑Jia Li; YinYin Liu; Li‑Na Ma; Jun‑Hua Pu; JunXian Lu; Xiu‑Jun Tang; Yu‑shi Gao (Environmental Science and Pollution Research, 2022)

Protective effects of fowl-origin cadmium-tolerant lactobacillus against sub-chronic cadmium-induced toxicity in chickens - Da-Wei Chen; Hui-Jia Li; YinYin Liu; Li-Na Ma; Jun-Hua Pu; JunXian Lu; Xiu-Jun Tang; Yu-shi Gao (Environmental Science and Pollution Research, 2022)

Maternal exposure to cooking oil fumes during pregnancy and autistic‐like behaviors in Chinese preschoolers - Jian-Hui Yang; Esben Strodl; Chuan-An Wu; Xiang-Yu Hou; Xiao-Na Yin; Guo-Min Wen; Deng-Li Sun; Dan-Xia Xian; Jing-Yi Chen; Ying-Jie Chen; Jing Chen; Wei-Qing Chen (Environmental Science and Pollution Research, 2022)

Efficient degradation of semi-coking wastewater in three-dimensional electro-Fenton by CuFe2O4 heterocatalyst - Wen-wen Gao; Ting Su; Wei Zhao; Zhi-fang Zhang; Miao Mu; Yong-hui Song; Xue-xue Zhang; Xin-yu Liu (Environmental Science and Pollution Research, 2022)

On the grinding effects of high-silicon iron tailings - Yun-hong Cheng; Bai-qiang Tong; Xiao-hui Sun; Jing-yu Zhang (Environmental Science and Pollution Research, 2022)

Urinary cadmium and peripheral blood telomere length predict the risk of renal function impairment: a study of 547 community residents of Shanxi, China - Jia-Chen Zhang; Shuang-Jing Li; Jian-Yong Guo; Guo-Yan Zhang; Hui Kang; Xiu-Jing Shi; Han Zhou; Yu-Fen Liang; Wei-Tong Shen; Li-Jian Lei (Environmental Science and Pollution Research, 2022)

Synthesis of γ-Fe2O3/La/Bi2WO6 composites for enhanced visible light-driven photocatalytic degradation of tetracycline hydrochloride - Zhi Li; XiaoMei Zhu; Yu Liu; Hui Liu; Bing Sun (Environmental Science and Pollution Research, 2022)

Low Levels of Serum Zinc Associate with Malnutrition Risk Assessed by the Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis - Wanting Yang; Xiaoyu Wang; Zihan Yu; Chaoqun Li; Mingyu Sun; Yifan Li; Yangyang Hui; Gaoyue Guo; Xiaofei Fan; Kui Jiang; Chao Sun (Biological Trace Element Research, 2022)

Differential expression and functional analysis of circRNA in the ovaries of Yili geese at different egg-laying stages - Xiao-yu Zhao; Ying-ping Wu; Hai-ying Li; Yan Cao; Zhi-yong Mei; Jia-hui Li (Genes & Genomics, 2022)

Reanalysis‐driven m ulti‐RCM high‐resolution simulation of precipitation within CORDEX East Asia Phase II - Jianping Tang; Yuxin Xiao; Pinhong Hui; Yutong Lu; Ke Yu (International Journal of Climatology, 2022)
Under the Coordinated Regional Downscaling Experiment‐East Asia second phase (CORDEX‐EA‐II) framework, the performances of three regional climate models (RCMs), including Weather Research and Forecasting (WRF) model, RegCM4 and Consortium for Small‐Scale Modelling model in Climate Mode (CCLM), in simulating the climatic distribution, diurnal variation and extremes of precipitation during 1989–2009 are evaluated. The RCMs are driven by the ERA‐Interim reanalysis and the evaluation is based on both the gridded gauge‐based and the satellite‐derived precipitation data. In general, the RCMs can reproduce the spatial pattern of the mean daily precipitation, with the spatial correlations (SCORs) larger than 0.66, and CCLM has the lowest root‐mean‐square error over East Asia. For the diurnal cycle of precipitation, WRF outperforms the other two RCMs despite the peak time about 3 hr ahead in some areas. RegCM4 overestimates the amplitude of the diurnal curve, and CCLM has limited ability to simulate the diurnal variation over most areas. All the three RCMs can reproduce the spatial patterns of the extreme indices, with the SCORs larger than 0.57. WRF and CCLM perform the best for the frequency of wet days (R1mm) and moderate rain (R20mm), respectively. The intensity indices are overestimated over most land areas, with relatively higher SCORs in WRF and relatively lower biases in RegCM4. The consecutive wet days (CWD) can be well simulated by WRF and CCLM; however, RegCM4 overestimates it over most regions in East Asia. The overestimation of the extreme intensity and frequency indices may be related to the higher water vapour content and the weaker water vapour divergence in the lower layer, as well as the higher mid‐layer geopotential height, especially in CCLM.

Genome of elegance coral Catalaphyllia jardinei (Euphylliidae) - Yifei Yu; Wenyan Nong; Wai Lok So; Yichun Xie; Ho Yin Yip; Jasmine Haimovitz; Thomas Swale; David M. Baker; William G. Bendena; Ting Fung Chan; Apple P. Y. Chui; Kwok Fai Lau; et al. (Frontiers in Marine Science, 2022)
Coral reefs are under stress throughout the world. To better understand the molecular mechanisms underlying coral biology and their genomic evolution, here we sequenced the genome and transcriptomes of elegance coral Catalaphyllia jardinei (Euphylliidae). This monotypic genus stony coral is widespread but rare, being found across the Indo-West Pacific, from the northern Indian Ocean, Australia, Philippines, to the South China Sea. Due to its popularity among aquarium hobbyists, it is an overexploited species collected in large quantities from the wild for aquarium trade. The assembled genome is ~ 651.3 Mb in total length and of high physical contiguity with a scaffold N50 size of 28.9 Mb. The gene copy numbers of abiotic stress regulator (heat shock protein family genes) and neuropeptides (GLWamide, GRFamide, PRGamide and HIRamide) are similar to other sequenced anthozoans, and we have also identified the first set of sesquiterpenoid biosynthetic pathway genes in coral. Sequencing of small RNAs allows us to identify 35 microRNAs in C. jardinei and update the number of conserved microRNAs in cnidarians. This study established a foundation for further investigation into the roles of sesquiterpenoids and microRNAs in development of coral and understand their responses to climate change. Due to the easiness to culture C. jardinei in reef tanks and the established resources in this study, we propose this species be adopted as a new laboratory model in environmental and ecological experiments aiming to understand coral biology and responses to environmental stressors.

Gregarious larval settlement mediates the responses of new recruits of the reef coral Acropora austera to ocean warming and acidification - Lei Jiang; Yu-Yang Zhang; Cheng-Yue Liu; Lin-Tao Huang; Hao-Ya Tong; Guo-Wei Zhou; Ming-Lan Guo; Tao Yuan; Hui Huang (Frontiers in Marine Science, 2022)
Gregarious larval settlement represents an important window for chimera formation in reef corals, yet it remains largely unknown how aggregated settlement and early chimerism could modify the performance and responses of coral recruits under elevated temperature and p CO 2 . In this study, single and aggregated recruits of the broadcast spawning coral Acropora austera were exposed to contrasts of two temperatures (28 versus 30.5°C) and p CO 2 levels (~500 versus 1000 μatm) for two weeks, and algal symbiont infection success, survivorship and growth were assessed. Results showed that symbiont infection success was mainly affected by temperature and recruit type, with reduced symbiont infection at increased temperature and consistently higher infection success in chimeric recruits compared to single recruits. Furthermore, although chimeric recruits with larger areal size had significantly higher survivorship in all treatments, the polyp-specific growth rates were considerably lower in chimeric entities than individual recruits. More importantly, the recruit type significantly influenced the responses of recruit polyp-specific growth rates to elevated temperature, with chimeras exhibiting lowered skeletal lateral growth under elevated temperature. These results demonstrate the benefits and costs associated with gregarious larval settlement for juvenile corals under ocean warming and acidification, and highlight the ecological role of larval settlement behavior in mediating the responses of coral recruits to climate change stressors.

Determination of extractable and non-extractable florfenicol residues as florfenicol amine in eggs by UPLC-MS/MS - Xia Li; Yu Zhang; Qifan Sun; Min Ding; Zengmei Li; Hui Yue; Ligang Deng; Lu Chen (Food Additives & Contaminants: Part A, 2022)

Clinical implementation of kVCT-guided tomotherapy with ClearRT - Bin Yang; Hui Geng; Tien Yee Amy Chang; Mei Yan Tse; Wai Wang Lam; Chen-Yu Huang; Tungho Wu; Ka Ki Lau; Kin Yin Cheung; George Chiu; Siu Ki Yu (Physical and Engineering Sciences in Medicine, 2022)

Naturally-Occurring Antibodies Against Bim are Decreased in Alzheimer’s Disease and Attenuate AD-type Pathology in a Mouse Model - Jie-Ming Jian; Dong-Yu Fan; Ding-Yuan Tian; Yuan Cheng; Pu-Yang Sun; Cheng-Rong Tan; Gui-Hua Zeng; Chen-Yang He; Ye-Ran Wang; Jie Zhu; Xiu-Qing Yao; Yan-Jiang Wang; et al. (Neuroscience Bulletin, 2022)

WASHC1 interacts with MCM2-7 complex to promote cell survival under replication stress - Yu Hong; He Sun; Xian Hong; Cai-Ping Yang; Daniel D. Billadeau; Tao Wang; Zhi-Hui Deng (Molecular Biology Reports, 2022)

A fast and efficient algorithm for multi-channel transcranial magnetic stimulation (TMS) signal denoising - Jinzhen Liu; Kaiwen Tian; Hui Xiong; Yu Zheng (Medical & Biological Engineering & Computing, 2022)

Two-stage hybrid network for segmentation of COVID-19 pneumonia lesions in CT images: a multicenter study - Yaxin Shang; Zechen Wei; Hui Hui; Xiaohu Li; Liang Li; Yongqiang Yu; Ligong Lu; Li Li; Hongjun Li; Qi Yang; Meiyun Wang; Meixiao Zhan; et al. (Medical & Biological Engineering & Computing, 2022)

Influence of vessel upsizing on pollution emissions along Far East–Europe trunk routes - Hui-Huang Tai; Yu-Meng Wang (Environmental Science and Pollution Research, 2022)

ZAKβ Alleviates Oxidized Low-density Lipoprotein (ox-LDL)-Induced Apoptosis and B-type Natriuretic Peptide (BNP) Upregulation in Cardiomyoblast - Yueh-Min Lin; Jiro Hasegawa Situmorang; Jia-Zun Guan; Dennis Jine-Yuan Hsieh; Jaw-Ji Yang; Michael Yu-Chih Chen; Ching-Hui Loh; Chia-Hua Kuo; Shang-Yeh Lu; Ying-Ming Liou; Chih-Yang Huang (Cell Biochemistry and Biophysics, 2022)

Paleo-karst zone and its control on reservoirs in the fourth member of the Sinian Dengying formation in the Moxi area, central Sichuan Basin - Qinyu Xia; Haijun Yan; Wei Xu; Lin Zhang; Qian Li; Wenjun Luo; Hui Deng; Xun Zhu; Xinyu Li; Jichen Yu (Carbonates and Evaporites, 2022)

Analysis of lateral orbitofrontal cortex activation on acquisition of fear extinction and neuronal activities in fear circuit - Cheng-Chia Shih; Yu-Hsuan Chang; Ruei-Jen Chiou; Chun-hui Chang (Brain Structure and Function, 2022)

MicroRNA-223 downregulation promotes HBx-induced podocyte pyroptosis by targeting the NLRP3 inflammasome - Yani Yu; Hui Dong; Yue Zhang; Jingyi Sun; Baoshuang Li; Yueqi Chen; Moxuan Feng; Xiaoqian Yang; Shengbo Gao; Wei Jiang (Archives of Virology, 2022)

Vertical distribution of planktonic ostracods (Halocyprididae) in the northeastern and central South China Sea: Significance of large‐sized species in deep waters - Tongchen Liao; Yehui Tan; Hui Liu; Linghui Yu; Kaizhi Li (Fisheries Oceanography, 2022)
The vertical distribution of species richness, abundance and biomass of planktonic ostracods down to a depth of 1000 m were studied in the northeastern South China Sea (NESCS) during March and in the central South China Sea (CTSCS) during September 2016. A total of 47 species of halocyprids were identified, with 46 species recorded in the NESCS and 28 species in the CTSCS. Most of the species observed were concentrated in the mesopelagic zone (200–1000 m), but the majority of species abundance and biomass occurred in the 25 m to 300 m water column. Results of statistical analysis showed that the vertical distribution of planktonic ostracods was associated with chlorophyll a concentration and sampling depth. The high abundance and species richness of ostracods in the NESCS were probably influenced by the Kuroshio intrusion and eddies leading to high levels of chlorophyll a concentration. The biomass of large‐sized individuals with low abundance is equal to or larger than, the extremely small‐sized individuals with high abundance, particularly in deep layers. The body sizes of planktonic ostracods were found to increase from surface to deeper water layers, indicating a trend of greater body length and higher biomass of ostracods in deep sea.

Numerical Simulation Study of the Horizontal Submerged Jet Based on the Wray–Agarwal Turbulence Model - Bo Hu; Chuan Wang; Hui Wang; Qian Yu; Jinhua Liu; Yong Zhu; Jie Ge; Xinxin Chen; Yang Yang (Journal of Marine Science and Engineering, 2022)
The horizontal submerged jet (HSJ), as a special form of jet, is widely used in aerospace, food and drug, water engineering, and other industries. In order to further understand the mechanism of the HSJ, the Wray–Agarwal turbulence model was used to predict the HSJ with different incidence heights H/D and Reynolds number (Re) conditions in this paper. The results show that the jet horizontal height H/D has a large influence on the flow field structure. The unsteady flow within the flow field is dominated by vortexes. In addition, their distribution is relatively independent of H/D. Under different H/D conditions, the axial velocity distribution of the jet has very high similarity, all of them have an obvious velocity inflection point at x = 10D. When H/D is small, the wall attachment effect of the jet and the boundary layer effect generated at the bottom of the fluid domain have a certain role in maintaining the velocity of the jet near the wall, resulting in a significantly higher axial velocity than other H/D conditions, up to 1.29 times. In this paper, we thoroughly investigated the structure of the internal flow field and velocity distribution of the submerged horizontal jet. The results have a guiding significance for engineering practice and academic research.

Spatial variability in the abundance and prey selection of the corallivorous snail Drupella spp. in the southeastern Hainan Island, China - Xinming Lei; Chengyue Liu; Yuyang Zhang; Xiaolei Yu; Jianhui Yang; Yong Luo; Guowei Zhou; Hui Huang (Frontiers in Marine Science, 2022)
Global climate change has caused extensive loss of biodiversity and ecosystem function globally, particularly in coral reefs in shallow tropical waters. As the corallivorous snails represent considerable disturbances to coral reefs across Indo-Pacific region, it is becoming a threat to coral health and recovery in the Hainan Island, South China Sea, but current-knowledge gap remains on the spatial distribution, prey preferences, and the influence factors related. Thus, we investigated the abundance distribution of Drupella spp. in relation to coral-prey selectivity, availability, and nutritional value. The snail density was heterogeneously distributed in the study area with an average of 0.72 ± 0.32 ind m −2 (varying from 0.09 ± 0.03 to 1.78 ± 0.39 ind m −2 ), and the snail density was found generally higher in locations with higher coral cover, which resulted in much lower density where their preferred corals became scarce. Despite the snails showing a positive preference for Acroporidae corals, they displayed dietary plasticity by changing with prey abundance and availability. Further, we found the electivity index of the coral prey related to the substrate types, and the nutritional value of prey was an additional important determinant in the prey preference, suggesting that the specific reef habitat and environmental context may alter the prey preference of Drupella spp. Combined, these results provide preliminary evidence that Drupella spp. is among the common corallivories in the reef regions of Hainan Island, and we recommend that large-scale monitoring programs assess the spatial-temporal trends to better understand the dynamics of predation linked to both anthropogenic and natural impacts.

Development of UPLC-MS/MS method for determining hainanmycin in foods of animal origin - Ke-xin Chi; Hang Yu; Ya-hui Guo; Yu-liang Cheng; Yun-fei Xie; Wei-rong Yao (Food Additives & Contaminants: Part A, 2022)

Comparative study on inhibitory effects of ferulic acid and p-coumaric acid on Salmonella Enteritidis biofilm formation - Jing-Guo Xu; Hui-Xue Hu; Jing-Yu Chen; Yan-Song Xue; Bekhzod Kodirkhonov; Bei-Zhong Han (World Journal of Microbiology and Biotechnology, 2022)

CREB1 contributes colorectal cancer cell plasticity by regulating lncRNA CCAT1 and NF-κB pathways - Bin Li; Lisi Zheng; Jiayi Ye; Chenmin Zhang; Jie Zhou; Qiaojuan Huang; Yanhua Guo; Luqin Wang; Peng Yu; Shurong Liu; Qiao Lin; Yuxia Luo; et al. (Science China Life Sciences, 2022)

Ketone Body Rescued Seizure Behavior of LRP1 Deficiency in Drosophila by Modulating Glutamate Transport - Jin-Ming Zhang; Ming-Jie Chen; Jiong-Hui He; Ya-Ping Li; Zhi-Cai Li; Zi-Jing Ye; Yong-Hui Bao; Bing-Jun Huang; Wen-Jie Zhang; Ping Kwan; Yu-Ling Mao; Jing-da Qiao (Journal of Molecular Neuroscience, 2022)

The Effects of Diameter, Length and Insertion Method on the Stability of Orthodontic Miniscrew - Wan-Ping Yu; Jian-Hong Yu; Shiuan-Hui Wang; Jui-Ting Hsu (Journal of Medical and Biological Engineering, 2022)

Trochanteric Nails for the Reduction of Intertrochanteric Fractures: A Biomechanical Analysis Based on Finite Element Analysis and DIC System - Ming-Tzu Tsai; Cheng-Hung Lee; Kun-Hui Chen; Yu-Chun Yen; Chun-Hsiang Wang; Shun-Ping Wang; Kuo-Chih Su (Journal of Medical and Biological Engineering, 2022)
Purpose Intertrochanteric fractures are common among femoral fractures in the elderly population. The trochanteric nail is a standard internal fixator used in treating femoral intertrochanteric fractures. The technique of femoral fracture reduction affects the postoperative outcome. Here, we applied finite element analysis (FEA) to study mechanical effects of different reduction approaches using the trochanteric nail in treating both stable and unstable intertrochanteric fractures. Methods We combined FEA and in vitro experiments using a digital imaging correlation (DIC) technique to study effects of different alignment conditions after treating 4 cases of intertrochanteric fractures using the trochanteric nail system. A downward force of 2250 N was applied to the femoral head, and the distal end of the femur was fixed. The observed indicators were the femur displacement, together with the stress on the femur and trochanteric nail system. In addition, the displacement distribution was analyzed using DIC. Results In the case of space reduction, the force was transmitted by the trochanteric nail system, resulting in greater stress imposed on the femur or the trochanteric nail system. In the case of closed reduction, the stress was much smaller. In the case of unstable fracture reduction, closed reduction was associated with a smaller contact area at the fracture site, resulting in greater stress on both trochanter and the trochanteric nail system. Conclusion When the trochanteric nail system was used for fixation, the fracture site was well aligned, reducing the stress on the femur or the trochanteric nail.

Biomechanical Effects of Bone Atrophy, Implant Design, and Vertical or Tilted of Posterior Implant on All-on-Four Concept Implantation: Finite Element Analysis - Heng-Li Huang; Ting-Wei Lin; Hui-Ling Tsai; Yu-Ling Wu; Aaron Yu-Jen Wu (Journal of Medical and Biological Engineering, 2022)

The safety degree evaluation of marine biodiversity in China - Xiu-Mei Fu; Wan-Yu Wu; Fang Yang; Shan-Shan Jiang; Shi-Qi Wang; Xiao-Yan Li; Hui-Ying Tang; Ying Liu; Chang-Yun Wang (Journal of Coastal Conservation, 2022)

Associations between seasonal ambient air pollution and adverse perinatal outcomes: a retrospective cohort study in Wenzhou, China - Hui-Jun Huang; Qiu-Yan Yu; Tian Zheng; Shan-Shan Wang; Xin-Jun Yang (Environmental Science and Pollution Research, 2022)

Pollution assessment, source identification, and health risks of heavy metals: a case study in a typical wheat–maize rotation area of eastern China - Fang Wan; Yongbo Teng; Xiuwen Zhang; Linsong Yu; Hong Pan; Hui Wang; Quangang Yang; Yanhong Lou; Yuping Zhuge (Environmental Geochemistry and Health, 2022)

The effects of dietary fermented wheat bran polysaccharides on mucosal and serum immune parameters, hepatopancreas antioxidant indicators, and immune-related gene expression of common carp (Cyprinus carpio) juveniles - Rui-Fang Wang; Yuan Wang; Jun Zhang; Mei-Qi Weng; Yu-Hui Liu; Qiu-Yan Cheng; Min Song; Yan-Ping Yang; Xiao-Ping An; Jing-Wei Qi (Aquaculture International, 2022)

Plant secondary metabolite and temperature determine the prevalence of Arsenophonus endosymbionts in aphid populations - Chun‐Yan Chang; Xiao‐Wan Sun; Pan‐Pan Tian; Ning‐Hui Miao; Yu‐Lin Zhang; Xiang‐Dong Liu (Environmental Microbiology, 2022)
Summary Transmission rate and role in hosts contribute to the prevalence of an endosymbiont. However, factors affecting transmission and role of facultative endosymbionts are still not well understood. Here, we illustrated that host plants and environmental temperatures affected the transmission, relative abundance and role of Arsenophonus in the cotton aphid Aphis gossypii . The transmission rate of this endosymbiont from mother aphids to offspring was relatively lower. High temperatures impeded the transmission, and infection rates declined as aphids were exposed to 30°C. Contents of amino acids and secondary metabolites were remarkably different among host plants. Aphids feeding on zucchini leaves containing a higher titre of amino acids and lower secondary metabolites harboured a relatively lower abundance of Arsenophonus . Concentrations of an amino acid and a plant secondary metabolite, cucurbitacin B, in aphid diet were not associated with Arsenophonus abundance. However, gossypol, another plant secondary metabolite, was strongly related with the abundance. Arsenophonus imparted a fitness benefit to aphids, and the benefit was dependent on host plants and gossypol concentration. In sum, plant secondary metabolite and environmental temperature affect transmission, relative abundance and role of Arsenophonus , which determine the endosymbiont prevalence in aphid populations.

Effects of Microplastics on Reproduction and Growth of Freshwater Live Feeds Daphnia magna - Chih-Hsiung Huang; Tah-Wei Chu; Chiu-Hui Kuo; Ming-Chang Hong; Yu-Yun Chen; Bonien Chen (Fishes, 2022)
In recent years, much research has focused on studying the damage caused by microplastics to the ecological environment and human health. Indeed, MPs are often consumed by shellfishes and zooplanktons due to their similarity in size to POM (particular organic matter). Especially in zooplankton, the accumulation of MPs in the body affects the reproductive system and the growth rate of juveniles. Moreover, toxins derived from MPs are continuously accumulated in predators of zooplankton and impact the whole ecosystem across the food chain. In this work, we found that even though MPs were internalized by and adherent around Daphnia magna, there were no significant differences in the survival rate of their adults and offspring. However, the population of ovigerous adults under high MPs exposure for 7 days decreased significantly, suggesting an extension of the days of sexual maturity in D. magna. The removal of MPs after 7 days’ MPs treatment resulted in an increase in D. magna juveniles and neonates which indicated their growth was reduced or inhibited in the MPs environment. Overall, the uptake of MPs led to negative effects on population reproduction and the growth of offspring in D. magna.

Correction to: Matrine Treatment Blocks NogoA-Induced Neural Inhibitory Signaling Pathway in Ongoing Experimental Autoimmune Encephalomyelitis - Quan-Cheng Kan; Hui-Jun Zhang; Yuan Zhang; Xing Li; Yu-Ming Xu; Rodolfo Thome; Ming-Liang Zhang; Nan Liu; Yao-Juan Chu; Guang-Xian Zhang; Lin Zhu (Molecular Neurobiology, 2022)

Validation and error analysis of wave-modified ocean surface currents in the northwestern Pacific Ocean - Zhenli Hui; Ying Li; Jia Sun; Long Yu; Xia Ju; Xuejun Xiong (Journal of Oceanology and Limnology, 2022)

Association between Lake Sediment Nutrients and Climate Change, Human Activities: A Time-Series Analysis - Linjie Wang; Xiangang Zeng; Hui Yu (Environmental Management, 2022)

Transformation of HBCDs by Rhodococcus sp. stu-38 - Fei Yu; Wenqi Luo; Yuyang Li; Shanshan Meng; Xianbin Lin; Lele Li; Xueying Ye; Hui Wang; Tao Peng; Tongwang Huang; Zhong Hu (Current Microbiology, 2022)

Grain size-dependent geochemical evidence reveals provenance and implications of aeolian sands, Dinggye region, southern Tibet - You-gui Chen; Mei-hui Pan; Ze-wen Hao; Yu-han Qi; Chen-lu Li (Journal of Mountain Science, 2022)

Streptococcus vulneris sp. nov., isolated from wound of patient with diabetic foot ulcer (DFU) - Jen-hao Chung; Li-Ting Wang; Yi-Sheng Chen; Yun-Shien Lee; Shih-Ting Lin; Yu-Chung Chang; Hui-Chung Wu; Yu-Jie Dai; Wei-Qi Liao; Fan-Ching Kao; Jui-hsiang Li (Archives of Microbiology, 2022)

Astragaloside IV improved antioxidative stress capacity and related gene expression of the Keap1‐Nrf2 pathway in grass carp ( Ctenopharyngodon idella ) hepatocytes under heat stress - Hua Liu; Ying Yang; Ying‐Ying Yu; Jing‐Jing Feng; Xiao‐Xue Bao; Jun Zhao; Hui Yu (Journal of Fish Biology, 2022)
This study aims to investigate the protective effects of astragaloside IV (AS‐IV) on the hepatocytes of grass carp ( Ctenopharyngodon idella ) on heat stress. Cultured cells were treated with AS‐IV (0, 50, 100 and 200 μg/ml) at 28°C for 24 h and then exposed to heat stress by increasing the culturing temperature (32 ± 0.5°C) for 6 h. The increased temperatures significantly reduced cell viability and superoxide dismutase (SOD) activity, and increased malondialdehyde (MDA) levels in the 0 μg/ml AS‐IV treatment group at 32°C, but the grass carp hepatocytes treated with 100 and 200 μg/ml AS‐IV had significantly increased cell viability and SOD activity and decreased MDA levels. The mRNA levels of keap1a , keap1b , nrf2 , gsh‐px , cat , cu‐zn sod , mgst1 and il‐6 were significantly lower in the 0 μg/ml AS‐IV treatment group at 32°C, while those of keap1a , nrf2 , gsh‐px , cat , cu‐zn sod , gstp1 , ho‐1 and il‐6 were significantly higher in cells treated with 100 or 200 μg/ml AS‐IV. Our findings indicate that AS‐IV could enhance the antioxidative stress capacity of grass carp hepatocytes under heat stress, and its mechanism may be associated with the activation of the Keap1‐Nrf2 pathway. Thus, these results provide new insights into how to alleviate heat stress in grass carp.

Remarkable effects of microbial factors on soil phosphorus bioavailability: A country‐scale study - Jing‐li Lu; Pu Jia; Shi‐wei Feng; Yu‐tao Wang; Jin Zheng; Shu‐ning Ou; Zhuo‐hui Wu; Bin Liao; Wen‐sheng Shu; Jie‐Liang Liang; Jin‐tian Li (Global Change Biology, 2022)
Low soil phosphorus (P) bioavailability causes the widespread occurrence of P‐limited terrestrial ecosystems around the globe. Exploring the factors influencing soil P bioavailability at large spatial scales is critical for managing these ecosystems. However, previous studies have mostly focused on abiotic factors. In this study, we explored the effects of microbial factors on soil P bioavailability of terrestrial ecosystems using a country‐scale sampling effort. Our results showed that soil microbial biomass carbon (MBC) and acid phosphatase were important predictors of soil P bioavailability of agro‐ and natural ecosystems across China although they appeared less important than total soil P. The two microbial factors had a positive effect on soil P bioavailability of both ecosystem types and were able to mediate the effects of several abiotic factors (e.g., mean annual temperature). Meanwhile, we revealed that soil phytase could affect soil P bioavailability at the country scale via ways similar to those of soil MBC and acid phosphatase, a pattern being more pronounced in agroecosystems than in natural ecosystems. Moreover, we obtained evidence for the positive effects of microbial genes encoding these enzymes on soil P bioavailability at the country scale although their effect sizes varied between the two ecosystem types. Taken together, this study demonstrated the remarkable effects of microbial factors on soil P bioavailability at a large spatial scale, highlighting the importance to consider microbial factors in managing the widespread P‐limited terrestrial ecosystems.

An inactivating mutation in the vacuolar arginine exporter gene Vae results in culture degeneration in the fungus Metarhizium robertsii - Hui Song; Yuting Bao; Mingxiang Zhang; Shuxing Liu; Chaonan Yu; Jin Dai; Congcong Wu; Dan Tang; Weiguo Fang (Environmental Microbiology, 2022)
Summary Culture degeneration usually results in great commercial losses in the economically important filamentous fungi, but the genetic causes of the degeneration remain elusive. In the fungus Metarhizium robertsii , we found that deletion of the vacuolar arginine exporter gene Vae caused culture degeneration. Compared to the WT strain, the mutant showed increased apoptosis, reactive oxygen species (ROS) level and mitochondrial membrane potential collapse, reduced conidial yield and abnormal lipid droplet formation. The extent of the degeneration in the mutant gradually increased over the successive subculturing, which eventually became irreversible; compared to the third subculture of the mutant, the seventh subculture showed a lower conidial yield and pathogenicity to insects, stronger apoptosis, higher ROS level and a smaller number of conidial lipid droplets. Incorporation of the genomic clone of Vae could not restore the WT phenotypes in the seventh subculture, but could in the third one. Loss‐of‐function in Vae resulted in vacuolar arginine accumulation and reduction in the cytosolic arginine. This downregulated the expression of the regulator CAG9 of G protein signalling pathway, which accounted for most of the phenotypic changes associated with the degeneration of the mutant. We identified a deleterious mutation that causes culture degeneration in a filamentous fugus.

Cadinane-type sesquiterpenes with potential anti-inflammatory and anti-HIV activities from the stems and leaves of Mappianthus iodoides - Yan-Ping Liu; Xiao-Mei Yu; Ze-Hua Qiao; Bo Jiang; Lan Xie; Hao-Xuan Tang; Xiao Liang; Yan-Hui Fu (Natural Product Research, 2022)

Effects of Dietary Nano-Curcumin Supplementation on Growth Performance, Glucose Metabolism, and Endoplasmic Reticulum Stress in Juvenile Largemouth Bass, Micropterus salmoides - Xiaoxue Bao; Mingshi Chen; Yuhua Yue; Hua Liu; Ying Yang; Hui Yu; Yingying Yu; Ning Duan (Frontiers in Marine Science, 2022)
This study evaluated the effects of nano-curcumin on growth performance, mucosal immunity, antioxidant response, glucose metabolism, and endoplasmic reticulum stress in largemouth bass. Three groups (three replicates/group) of 270 fish with the mean body weight of 7.00 ± 0.02 g were fed with diets containing 0% (control), 0.1%, and 0.2% nano-curcumin for 60 days. The results showed that dietary supplementation of nano-curcumin had no significant effects on the growth performance, body composition, lysozyme (LYZ), and alkaline phosphatase (AKP) in skin mucus, superoxide dismutase (SOD), and catalase (CAT) activity in serum of largemouth bass. However, dietary supplementation with 0.2% nano-curcumin significantly increased peroxidase (POD) activity in skin mucus and decreased the serum MDA activity compared with the control group. Moreover, dietary supplementation of 0.2% nano-curcumin significantly decreased the levels of serum glucose and liver glycogen, which may be mainly related to the increased gene expression of glucose transporter 2 ( GLUT2 ), glucokinase ( GK ), phosphofructokinase ( PFK ), and pyruvate kinase ( PK ). At the same time, the hepatic gene expression of glucose-regulated protein78 ( GRP78 ), activating transcription factor6 ( ATF6 ), inositol-requiring enzyme 1 ( IRE ), and eukaryotic initiation factor 2α ( eIF2α ) in the 0.2% nano-curcumin group were rapidly suppressed, indicating that adding 0.2% nano-curcumin to the diet can alleviate endoplasmic reticulum stress (ERS) in fish. In conclusion, diets supplemented with 0.2% nano-curcumin effectively improved mucosal immunity, antioxidant properties, and glucose metabolism and alleviated ERS induced by long-term carbohydrate intake in largemouth bass.

Identification of the Largest SCA36 Pedigree in Asia: with Multimodel Neuroimaging Evaluation for the First Time - Yue Xie; Zhao Chen; Zhe Long; Rui-Ting Chen; Yi-Zheng Jiang; Ming-Jie Liu; Lin-Liu Peng; Hui-Rong Peng; Na Wan; Guangdong Zou; Chun-Rong Wang; Yu-Ting Shi; et al. (The Cerebellum, 2022)

Metabolic Regulation: A Potential Strategy for Rescuing Stem Cell Senescence - Wenxin Zhang; Jiayu Li; Yuchi Duan; Yanlin Li; Yanan Sun; Hui Sun; Xiao Yu; Xingyu Gao; Chang Zhang; Haiying Zhang; Yingai Shi; Xu He (Stem Cell Reviews and Reports, 2022)

Mechanical Properties and Deterioration Mechanism of Remolded Carbonaceous Mudstone Exposed to Wetting–Drying Cycles - Yu-Ling Yang; Tao Zhang; Song-Yu Liu; Jun-Hui Luo (Rock Mechanics and Rock Engineering, 2022)

Genome-Wide Comparative Analysis of Genetic Diversity of Regular and Specialty Maize Inbred Lines Through Genotyping by Target Sequencing (GBTS) - Diansi Yu; Lili Song; Wei Gu; Yuan Guan; Hui Wang; Biao Shi; Zhicheng Zhou; Hongjian Zheng; Yueguo Jiang; Yonglei Yao (Plant Molecular Biology Reporter, 2022)

Wuzi Yanzong pill attenuates MPTP-induced Parkinson’s Disease via PI3K/Akt signaling pathway - Wei Hang; Hui-jie Fan; Yan-rong Li; Qi Xiao; Lu Jia; Li-juan Song; Yao Gao; Xiao-ming Jin; Bao-guo Xiao; Jie-zhong Yu; Cun-gen Ma; Zhi Chai (Metabolic Brain Disease, 2022)

Association between MAP3K4 gene polymorphisms and the risk of schizophrenia susceptibility in a Northeast Chinese Han population - Yang Sun; Ye Lv; Hui-Wen Ren; Guan-Yu Wang; Li-Na Xuan; Yi-Yang Luo; Zhi-Lin Luan (Metabolic Brain Disease, 2022)

Use of piggyBac Transposon System Constructed Murine Breast Cancer Model for Reporter Gene Imaging and Characterization of Metastatic Tumor Cells - Ying-Ling Chen; Yung-Cheng Wang; Kuei-Yuan Hou; Min-Ying Lin; Yu-Chuan Lin; Hui-Yen Chuang; Yi-Jang Lee (Journal of Medical and Biological Engineering, 2022)

Asian dust storms result in a higher risk of the silicosis hospital admissions - Tsai-Ching Liu; Hui-Hsuan Tang; Shu-Yi Lei; Yu-I Peng (Journal of Environmental Health Science and Engineering, 2022)

Isolation and Characterization of a Novel Lytic Halotolerant Phage from Yuncheng Saline Lake - Chuan-Xu Wang; Ai-Hua Zhao; Hui-Ying Yu; Ling-Li Wang; Xin Li (Indian Journal of Microbiology, 2022)

Life cycle assessment of rice bran oil production: a case study in China - Li-Hui Sun; Yu-Ying Wang; Yu-Qing Gong (Environmental Science and Pollution Research, 2022)

Flow-slide characteristics and failure mechanism of shallow landslides in granite residual soil under heavy rainfall - Hui-lin Bai; Wen-kai Feng; Shuang-quan Li; Long-zhen Ye; Zhong-teng Wu; Rui Hu; Hong-chuan Dai; Yun-peng Hu; Xiao-yu Yi; Peng-cheng Deng (Journal of Mountain Science, 2022)

Cytogenetic analysis of 2959 couples with spontaneous abortion and detailed analysis of rare karyotypes - Zong-Yu Miao; Xiao-Yan Liu; Hong Wu; Xiao-Fei Hou; Na Lv; Xin Wang; Hui-Yuan Shao (Journal of Genetics, 2022)

Neorhizobium xiangyangii sp. nov., isolated from a highland barley cultivation soil in Qamdo, Tibet - Hu Pan; Zi-Qiong Zhou; Guo-Wei He; Jie Zhou; Kai Jin; Hu-Hu Liu; Chong Wang; Hui Yang; Yao-Bin Yu; Yun Tian (Archives of Microbiology, 2022)

Alteromonas oceanisediminis sp. nov., isolated from deep-sea sediment - Xiao-Yu Zhang; Zhen Wang; Jun-Hui Cheng; Hui-Hui Fu; Yu-Zhong Zhang; Xiu-Lan Chen; Xi-Ying Zhang; Xiao-Yan Song; Yu-Qiang Zhang; Fei Xu (Archives of Microbiology, 2022)

Effects of dietary protein concentration on growth and anti-oxidant capacity of coho salmon Oncorhynchus kisutch (Walbaum, 1792) alevins - Cong-mei Xu; Hai-rui Yu; Qin Zhang; Ling-yao Li; Jing-jing Fan; Meng-jie Guo; Fang-hui Li; Xiang-yi Qiu; Ling-ling Shan (Aquaculture International, 2022)

Intelligent identification method and application of seismic faults based on a balanced classification network - Jing Yang; Ren-Wei Ding; Hui-Yong Wang; Nian-Tian Lin; Li-Hong Zhao; Shuo Zhao; Yu-Jie Zhang (Applied Geophysics, 2022)

Jeotgalibacillus aurantiacus sp. nov., a novel orange-pigmented species with a carotenoid biosynthetic gene cluster, isolated from wetland soil - Hui-Ning Jiang; Shuai-Ting Yun; Bao-Xun Wang; Ming-Jing Zhang; Yu Ma; Yan-Xia Zhou (Antonie van Leeuwenhoek, 2022)

Differences in Fatty Acids and Lipids of Massive and Branching Reef-Building Corals and Response to Environmental Changes - Chengyue Liu; Yuyang Zhang; Lintao Huang; Xiaolei Yu; Yong Luo; Lei Jiang; Youfang Sun; Sheng Liu; Hui Huang (Frontiers in Marine Science, 2022)
Reef-building corals present various colony morphologies that may greatly influence their nutritional ecology. Fatty acids (FAs) and lipids are important components of corals and have been increasingly used to research the nutritional ecology of corals. In this study, we examined the symbiodiniaceae density, corallite area, total lipid content, and FAs composition of 14 species of corals with different colony morphologies. The results showed that the different colony morphology of coral was significantly correlated with the corallite area but not with the symbiodiniaceae density. Massive corals, with a large corallite area (7.16 ± 6.29 mm 2 ), could ingest a high quantity of food, leading to high levels of total lipid content and unsaturated FAs [particularly n-6 polyunsaturated FAs (PUFAs) and monounsaturated FAs]. For branching corals, the total lipid content and saturated FAs (SFAs, 16:0 and 18:0) were significantly positively correlated with the Symbiodiniaceae density, indicating that branching corals are predominantly autotrophic. Moreover, compared with healthy corals, bleached corals consume larger amounts of stored energy (such as lipids and SFAs) to maintain their normal physiological functions. Although bleached corals may obtain PUFAs from heterotrophic assimilation or biosynthesize, the efficiency is too low to sufficiently replenish essential PUFAs in a short time. Overall, massive corals with more initial total lipid content and PUFAs exhibit an advantage under adverse environmental conditions.

Comparative transcriptome analysis of pollen and anther wall reveals novel insights into the regulatory mechanisms underlying anther wall development and its dehiscence in rice - Woo-Jong Hong; Su Kyoung Lee; Seok-Hui Kim; Yu-Jin Kim; Sunok Moon; Eui-Jung Kim; Jeniffer Silva; Ki-Hong Jung (Plant Cell Reports, 2022)

Development of novel polymorphic microsatellite markers for Picea brachytyla - Shuai-Peng Si; Chun-Jing Wang; Ji-Zhong Wan; Yu-Lin Qian; Chun-Hui Zhang (Molecular Biology Reports, 2022)

Kai-Xin-San Inhibits Tau Pathology and Neuronal Apoptosis in Aged SAMP8 Mice - Ya-Nan Jiao; Jing-Sheng Zhang; Wen-Jun Qiao; Shu-Yu Tian; Yi-Bin Wang; Chun-Yan Wang; Yan-Hui Zhang; Qi Zhang; Wen Li; Dong-Yu Min; Zhan-You Wang (Molecular Neurobiology, 2022)
Alzheimer’s disease (AD) is an age-related neurological disorder. Currently, there is no effective cure for AD due to its complexity in pathogenesis. In light of the complex pathogenesis of AD, the traditional Chinese medicine (TCM) formula Kai-Xin-San (KXS), which was used for amnesia treatment, has been proved to improve cognitive function in AD animal models. However, the active ingredients and the mechanism of KXS have not yet been clearly elucidated. In this study, network pharmacology analysis predicts that KXS yields 168 candidate compounds acting on 863 potential targets, 30 of which are associated with AD. Enrichment analysis revealed that the therapeutic mechanisms of KXS for AD are associated with the inhibition of Tau protein hyperphosphorylation, inflammation, and apoptosis. Therefore, we chose 7-month-old senescence-accelerated mouse prone 8 (SAMP8) mice as AD mouse model, which harbors the behavioral and pathological hallmarks of AD. Subsequently, the potential underlying action mechanisms of KXS on AD predicted by the network pharmacology analyses were experimentally validated in SAMP8 mice after intragastric administration of KXS for 3 months. We observed that KXS upregulated AKT phosphorylation, suppressed GSK3β and CDK5 activation, and inhibited the TLR4/MyD88/NF-κB signaling pathway to attenuate Tau hyperphosphorylation and neuroinflammation, thus suppressing neuronal apoptosis and improving the cognitive impairment of aged SAMP8 mice. Taken together, our findings reveal a multi-component and multi-target therapeutic mechanism of KXS for attenuating the progression of AD, contributing to the future development of TCM modernization, including KXS, and broader clinical application. Graphical abstract

A20 alleviated caspase-1-mediated pyroptosis and inflammation stimulated by Porphyromonas gingivalis lipopolysaccharide and nicotine through autophagy enhancement - Hui Tang; Yu Ye; Lu Li; Yi Zhou; Liguang Hou; Shuangshuang Ren; Yan Xu (Human Cell, 2022)

Spatial conflict simulation of land-use based on human-land-landscape elements intercoordination: a case study in Tianjin, China - Xiangping Liu; Zhen Zhang; Mingxin Li; Yanhua Fu; Yu Hui (Environmental Monitoring and Assessment, 2022)

Spatial Regionalization on Surface Ozone in the Yangtze River Delta of China - Lei Tong; Hang Xiao; Hui Yi; Yu Liu; Jie Zheng; Cenyan Huang; Mengmeng He (Asia-Pacific Journal of Atmospheric Sciences, 2022)

Ecological source identification based on the PSR model framework and structural features: a case study in Tianjin, China - Xiangping Liu; Zhen Zhang; Mingxin Li; Yanhua Fu; Yu Hui (Arabian Journal of Geosciences, 2022)

Correction to: Arthrobacter wenxiniae sp. nov., a novel plant growth-promoting rhizobacteria species harbouring a carotenoids biosynthetic gene cluster - Yu-chen Sun; Pengbo Sun; Jing Xue; Yunpeng Du; Hui Yan; Li-wei Wang; Xin-xin Yi; Jian-guang Sun; Xiuhai Zhang; Jun-lian Gao (Antonie van Leeuwenhoek, 2022)

Chromosome-Scale Assembly and Characterization of the Albino Northern Snakehead, Channa argus var. (Teleostei: Channidae) Genome - Chaowei Zhou; Yan Li; Yan Zhou; Yu Zou; Dengyue Yuan; Xingxing Deng; Luo Lei; Jian Su; Chengke Zhu; Hua Ye; Hui Luo; Guangjun Lv; et al. (Frontiers in Marine Science, 2022)
Northern snakehead, Channa argus ( C. argus ), is an important economic and ecological fish species. The wild population of the species was sharply declined in the last decade. A high-quality reference genome could lay a solid foundation for the genetic and conservation studies for C. argus . In this work, we report a chromosomal genome assembly with PacBio and Hi-C technology using the albino northern snakehead, a color variety of C. argus . A 644.1-Mb genome with 24 chromosomes was obtained with a contig and scaffold N50 of 11.78 and 27.8 Mb, respectively. We inferred that C. argus diverged from A. testudineus around 85.6 million years ago. 514 expanded gene families and 214 positively selected genes were identified in the C. argus genome. The chromosome-level genome provides a valuable high-quality genomic resource for population, as well as genetic and evolutionary studies for C. argus and other species in Channidae.

Rate-Dependent Characteristics of Damage and Roughness Degradation of Three-Dimensional Artificial Joint Surfaces - Hui Shen; Yaqun Liu; Haibo Li; Duohua Wu; Xiang Xia; Bo Liu; Chong Yu (Rock Mechanics and Rock Engineering, 2022)

Dissecting the Neural Circuitry for Pain Modulation and Chronic Pain: Insights from Optogenetics - Fang Guo; Yu Du; Feng-Hui Qu; Shi-Da Lin; Zhong Chen; Shi-Hong Zhang (Neuroscience Bulletin, 2022)
Pain is an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. The processing of pain involves complicated modulation at the levels of the periphery, spinal cord, and brain. The pathogenesis of chronic pain is still not fully understood, which makes the clinical treatment challenging. Optogenetics, which combines optical and genetic technologies, can precisely intervene in the activity of specific groups of neurons and elements of the related circuits. Taking advantage of optogenetics, researchers have achieved a body of new findings that shed light on the cellular and circuit mechanisms of pain transmission, pain modulation, and chronic pain both in the periphery and the central nervous system. In this review, we summarize recent findings in pain research using optogenetic approaches and discuss their significance in understanding the pathogenesis of chronic pain.

Anterior Cingulate Cortex Mediates Hyperalgesia and Anxiety Induced by Chronic Pancreatitis in Rats - Dan Ren; Jia-Ni Li; Xin-Tong Qiu; Fa-Ping Wan; Zhen-Yu Wu; Bo-Yuan Fan; Ming-Ming Zhang; Tao Chen; Hui Li; Yang Bai; Yun-Qing Li (Neuroscience Bulletin, 2022)
Central sensitization is essential in maintaining chronic pain induced by chronic pancreatitis (CP), but cortical modulation of painful CP remains elusive. Here, we examined the role of the anterior cingulate cortex (ACC) in the pathogenesis of abdominal hyperalgesia in a rat model of CP induced by intraductal administration of trinitrobenzene sulfonic acid (TNBS). TNBS treatment resulted in long-term abdominal hyperalgesia and anxiety in rats. Morphological data indicated that painful CP induced a significant increase in FOS-expressing neurons in the nucleus tractus solitarii (NTS) and ACC, and some FOS-expressing neurons in the NTS projected to the ACC. In addition, a larger portion of ascending fibers from the NTS innervated pyramidal neurons, the neural subpopulation primarily expressing FOS under the condition of painful CP, rather than GABAergic neurons within the ACC. CP rats showed increased expression of vesicular glutamate transporter 1, and increased membrane trafficking and phosphorylation of the N -methyl-D-aspartate receptor (NMDAR) subunit NR2B and the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) subunit GluR1 within the ACC. Microinjection of NMDAR and AMPAR antagonists into the ACC to block excitatory synaptic transmission significantly attenuated abdominal hyperalgesia in CP rats, which was similar to the analgesic effect of endomorphins injected into the ACC. Specifically inhibiting the excitability of ACC pyramidal cells via chemogenetics reduced both hyperalgesia and comorbid anxiety, whereas activating these neurons via optogenetics failed to aggravate hyperalgesia and anxiety in CP rats. Taken together, these findings provide neurocircuit, biochemical, and behavioral evidence for involvement of the ACC in hyperalgesia and anxiety in CP rats, as well as novel insights into the cortical modulation of painful CP, and highlights the ACC as a potential target for neuromodulatory interventions in the treatment of painful CP.

Effects of PHD and HSP90 on erythropoietin production in yak (Bos grunniens) renal interstitial fibroblast-like cells under hypoxia - Yan Cui; Hui Li; Si-Jiu Yu; Seth Yaw Afedo; Xue-Feng Bai (Journal of Molecular Histology, 2022)

Genetic diversity and population structure of Curcuma alismatifolia Gagnep. accessions revealed by SSR markers - Hui-Wen Yu; Ling-Jun Ke; Yi-Lan Xiao; Si-Jia Chen; Yuan-Yuan Li; Qi-Lin Tian; Yun-He Li; Jin-Shui Lin; Luan-Mei Lu (Genetic Resources and Crop Evolution, 2022)

Localization of QTL for cold tolerance at the germination stage of rice (Oryza sativa L.) using recombinant inbred lines - Liangzi Cao; Shukun Jiang; Guohua Ding; Tongtong Wang; Liangming Bai; Jinsong Zhou; Yu Luo; Tianshu Xia; Hui Jiang; Kai Liu; Xueyang Wang; Guang Yang; et al. (Genetic Resources and Crop Evolution, 2022)
The cold tolerance of germinating direct-sown rice ( Oryza sativa L.) has an increased rate of emergence, which ensures vigorous seedling growth. Research on QTL localization for cold tolerance at the germination stage can assist in molecular marker-assisted selection and enhance breeding efficiency. In this study, 94 populations of recombinant self-incompatible lines from Heigu and Ha 9366 were selected to investigate germination rates at low temperatures. It was found that two QTL loci (qLTG-3 and qLTG-12) were located at different germination times on chromosomes 3 and 12, respectively. The two QTLs at three different germination times, located using QTL, accounted for 21.3–25.9% of the phenotypic variation. Moreover, a reciprocal effect was detected between the two QTLs. The double QTLs increased the germination rate by 22–27% in this population. Additionally, qLTG-12 improved cold tolerance at the seedling stage. The results of this study might provide the materials and molecular markers for future molecular marker-assisted breeding for cold tolerance at the germination stage.

Association between congenital heart defects and maternal manganese and iron concentrations: a case–control study in China - Meixian Wang; Yan Tian; Ping Yu; Nana Li; Ying Deng; Lu Li; Hong Kang; Dapeng Chen; Hui Wang; Zhen Liu; Juan Liang (Environmental Science and Pollution Research, 2022)
To investigate the correlation between maternal manganese and iron concentrations and the risk of CHD among their infant. A multi-center hospital-based case control study was conducted in China. There were 322 cases and 333 controls have been selected from pregnant women who received prenatal examinations. Correlations between CHDs and maternal manganese and iron concentrations were estimated by conditional logistic regression. Moreover, the interaction between manganese and iron on CHDs was analyzed. Compared with the controls, mothers whose hair manganese concentration was 3.01 μg/g or more were more likely to have a child with CHD than those with a lower concentration. The adjusted OR was 2.68 (95%CI = 1.44–4.99). The results suggested that mothers whose iron content was 52.95 μg/g or more had a significantly higher risk of having a child with CHD ( aOR = 2.87, 95%CI = 1.54–5.37). No interaction between maternal manganese and iron concentrations was observed in the multiplicative or additive model. The concurrently existing high concentration of manganese and iron may bring higher risk of CHD ( OR = 7.02). Women with excessive manganese concentrations have a significantly increased risk of having offspring with CHDs. The high maternal iron status also correlates with CHDs. The concurrently existing high concentration of manganese and iron may bring higher risk of CHD.

Correction to: Role of HMGB1 in TNF-α Combined with Z-VAD-fmk-Induced L929 Cells Necroptosis - Zhao Lei; Can Yu; Xia Li; Li-Hua Huang; Zhi-Qiang Li; Hong-Wei Zhu; Duo Han; Hui Huang; Xiao Yu (Biochemical Genetics, 2022)

Role of HMGB1 in TNF-α Combined with Z-VAD-fmk-Induced L929 Cells Necroptosis - Can Yu; Zhao Lei; Xia Li; Li-Hua Huang; Zhi-Qiang Li; Hong-Wei Zhu; Duo Han; Hui Huang; Xiao Yu (Biochemical Genetics, 2022)

A study of health management of LWD tool based on data-driven and model-driven - Hui Li; Zi-Hua He; Yu-ting Zhang; Jin Feng; Zun-Yi Jian; Yi-Bo Jiang (Acta Geophysica, 2022)

Structure, antioxidant property and protection on PC12 of a polysaccharide isolated and screened from Abelmoschus esculentus L.Moench (okra) - Li-Chao Pan; Yang-Yang Sun; Xiao-Ling Zhang; Zhen-Yuan Zhu; Chun-Yu Liu; Hui-Qing Sun; Xue-Qing Geng; Wei Jiang; Jia-He Wang (Natural Product Research, 2022)

Anti-inflammatory constituents from Phyllostachys makinoi Hayata - Chia-Ching Liaw; Yu-Chi Lin; Shao-Yu Wu; Jenny Chun-Ling Kuo; Zhi-Hu Lin; Kai-Wei Lin; Huang Hui-Chi; Li-Ming Yang Kuo; Yao-Haur Kuo (Natural Product Research, 2022)

Diketopiperazine and enterotoxin analogues from the mangrove derived-soil Streptomyces sp. SCSIO 41400 and their biological evaluation - Meng-Meng Song; Yu-Hui Xie; Wei-Hao Chen; Yi-Wei Hu; Kai Zhao; Yong-Hong Liu; Xiao-Long Huang; Qing-Chao Liu; Jun-Feng Wang (Natural Product Research, 2022)

Avilamycin production enhancement by mutagenesis and fermentation optimization in Streptomyces viridochromogenes - Guanghai Yu; Haifen Peng; Jian Cao; Aimei Liao; Pan Long; Jihong Huang; Ming Hui (World Journal of Microbiology and Biotechnology, 2022)

Functional characterization of tyrosine decarboxylase genes that contribute to acteoside biosynthesis in Rehmannia glutinosa - Yan Hui Yang; Mu Rong Yang; Jian Yu Zhu; Ke Wei Dong; Yan Jie Yi; Rui Fang Li; Lei Zeng; Chang Fu Zhang (Planta, 2022)

Ectopic expression of GmRNF1a encoding a soybean E3 ubiquitin ligase affects Arabidopsis silique development and dehiscence - Zhongyi Yang; Yingjun Chi; Yanmei Cui; Zhen Wang; Dezhou Hu; Hui Yang; Javaid Akhter Bhat; Hui Wang; Guizhen Kan; Deyue Yu; Fang Huang (Planta, 2022)

Identification and Expression Analysis of the SBP-box Gene Family Related to Abiotic Stress in Tea Plant (Camellia sinensis (L.) O. Kuntze) - Rui-Min Teng; Yong-Xin Wang; Hui Li; Hao Liu; Yu Wang; Jing Zhuang (Plant Molecular Biology Reporter, 2022)

The management of bone defect using long non-coding RNA as a potential biomarker for regulating the osteogenic differentiation process - Jia-lin Liu; Yan-shi Liu; Mei-jie Zheng; Hui-yu He (Molecular Biology Reports, 2022)
Tissue engineered bone brings hope to the treatment of bone defects, and the osteogenic differentiation of stem cells is the key link. Inducing osteogenic differentiation of stem cells may be a potential approach to promote bone regeneration. In recent years, lncRNA has been studied in the field increasingly, which is believed can regulate cell cycle, proliferation, metastasis, differentiation and immunity, participating in a variety of physiology and pathology processes. At present, it has been confirmed that certain lncRNAs regulate the osteogenesis of stem cells and take part in mediating signaling pathways including Wnt/β-catenin, MAPK, TGF-β/BMP, and Notch pathways. Here, we provided an overview of lncRNA, reviewed its researches in the osteogenic differentiation of stem cells, emphasized the importance of lncRNA in bone regeneration, and focused on the roles of lncRNA in signaling pathways, in order to make adequate preparations for applying lncRNA to bone tissue Engineering, letting it regulate the osteogenic differentiation of stem cells for bone regeneration.

Hippocampal SIRT1-Mediated Synaptic Plasticity and Glutamatergic Neuronal Excitability Are Involved in Prolonged Cognitive Dysfunction of Neonatal Rats Exposed to Propofol - Lin-Hui Ma; Jie Wan; Jing Yan; Ning Wang; Yan-Ping Liu; Hai-Bi Wang; Cheng-Hua Zhou; Yu-Qing Wu (Molecular Neurobiology, 2022)

Fate of heavy metals and bacterial community composition following biogas slurry application in a single rice cropping system - Qiang Wang; Zhaoming Chen; Jun Zhao; Junwei Ma; Qiaogang Yu; Ping Zou; Hui Lin; Jinchuan Ma (Journal of Soils and Sediments, 2022)

The effect of preoperative statin treatment on acute kidney injury in elderly patients undergoing valve replacement surgery - Bing-qi Fu; Xue-biao Wei; Zedazhong Su; Ying-wen Lin; Zu-hui Ke; Tong Tan; Ji-yan Chen; Shou-hong Wang; Dan-qing Yu (European Journal of Clinical Pharmacology, 2022)

Comprehensive Hydrodynamic Fitness of an Estuary Channel and the Effects of a Water Diversion Inflow - Wei He; Aili Jiang; Jian Zhang; Hui Xu; Yang Xiao; Sheng Chen; Xiaodong Yu (Estuaries and Coasts, 2022)

Preparation and evaluation of Pd-Sn modified Ru-Ir electrode for denitrification of high chlorine ammonia–nitrogen wastewater - Zhen-xing Yang; Jie Shang; Guang-xu Yan; Yu-xian Wang; Shao-hui Guo (Environmental Science and Pollution Research, 2022)

Oxidative stress is involved in the activation of NF-κB signal pathway and immune inflammatory response in grass carp gill induced by cypermethrin and/or sulfamethoxazole - Baoying Li; Yu Wang; Hongjing Zhao; Kai Yin; Yachen Liu; Dongxu Wang; Hui Zong; Mingwei Xing (Environmental Science and Pollution Research, 2022)

Migration and abiotic transformation of estrone (E1) and estrone-3-sulfate (E1-3S) during soil column transport - Banghao Du; Weiwei Yu; Lun Yang; Gongduan Fan; Shuo Yang; Hui Jiang; Shenglan Bi; Cheng Yu (Environmental Geochemistry and Health, 2022)

Research of Super Typhoon Lekima: forecast, observation, numerical simulation and disaster survey - Jie Tang; Jianfang Fei; Hui Yu (Frontiers of Earth Science, 2022)

Application of the frequency-matching method in the probability forecast of landfalling typhoon rainfall - Rong Guo; Hui Yu; Zifeng Yu; Jie Tang; Lina Bai (Frontiers of Earth Science, 2022)

The impact of Typhoon Lekima (2019) on East China: a postevent survey in Wenzhou City and Taizhou City - Cong Zhou; Peiyan Chen; Shifang Yang; Feng Zheng; Hui Yu; Jie Tang; Yi Lu; Guoming Chen; Xiaoqing Lu; Xiping Zhang; Jing Sun (Frontiers of Earth Science, 2022)

Three-dimensional forward modeling and response characteristics analysis of foundation pit leakage electric-field considering electrokinetic effect - Chen Yu-Feng; Chen Hui; Deng Ju-Zhi; Liu Sui-Ming; Tang Wen-Wu; Wang Shuo (Applied Geophysics, 2022)