Phyllaciduloids E and F, two new cleistanthane diterpenoids from the leaves of Phyllanthus acidus - Hui-Chun Geng; Hong-Tao Zhu; Wei-Nong Yang; Dong Wang; Chong-Ren Yang; Ying-Jun Zhang (Natural Product Research, 2022)

Monoterpenoid indole alkaloids with potential neuroprotective activities from the stems and leaves of Melodinus cochinchinensis - Yu-Jie Li; Juan Li; Lan Xie; Jun-Yu Zhou; Qiu-Xuan Li; Rui-Yuan Yang; Yan-Ping Liu; Yan-Hui Fu (Natural Product Research, 2022)

Oxidative stress and DNA damage in earthworms induced by methyl tertiary-butyl ether in natural soils - Yanqiang Li; Jun Wang; Zhongkang Yang; Guangde Li; Zhongwen Zhang; Dexin Zhang; Hui Sun (Environmental Science and Pollution Research, 2022)

Modal Identification of Structures by Eliminating the Effect of the High Ocean Wind - Chun-Xu Qu; Chang-Chong Liu; Xiao-Mei Yang; Hui-Juan Liu; Hong-Nan Li; Yu-Feng Zhang (Journal of Marine Science and Engineering, 2022)
Tropical cyclone is a rapidly rotating storm system with severe excitation such as high wind. This severe excitation may change the performance of structures, such as bridges, wharves and wind turbine structures. It is very necessary to monitor this important change. Modal parameters are the ones to reflect the structural instinct behavior. However, many identification methods assume that the excitation is white noise, which is not the truth during high ocean wind excitation. Therefore, the modal identification method to deal with severe ocean wind excitation should be investigated. This paper proposes an innovative method to eliminate the effect of high ocean wind on modal identification. The formulation to generate an impulse response is described, where the effect of high wind is pointed. Then the elimination method is derived using the wind velocity spectrum and correlation function. After the wind field is simulated, the wind velocities and spectra at all accelerometer positions are obtained. The real impulse response form is obtained. Then, modal identification using the real impulse response is performed. Finally, a practical cable-stayed bridge is employed and modal identification is performed. The results show that the identified modes can reflect structural real behavior.

Effects of three feed attractants on the growth performance and meat quality of the largemouth bass (Micropterus salmoides) - Yuhua Yue; Mingshi Chen; Xiaoxue Bao; Yingying Yu; Wei Shi; Suksan Kumkhong; Yuhong Liu; Ying Yang; Hui Yu (Frontiers in Marine Science, 2022)
The trial was conducted to investigate the effects of limonene, allicin and betaine supplementation in low fish meal (FM) diet on growth performance, antioxidant capacity, meat quality and intestinal health in largemouth bass ( M. salmoides ). The biting-balls test and feeding trial were successively conducted. For the one, the results of the biting-ball test showed that with the increase of the concentration of the three attractants, the attracting effect firstly increased, then decreased, and the effect reached maximum at 0.2% concentration. ( P < 0.05). Further, a 9-week feeding trial was conducted using five diets, including a basal diet with 30% and 40% fish meal without attractant, 30% fish meal supplemented with 0.2% limonene, 0.2% allicin or 0.2% betaine (the diets were named FM30, FM40, FM30 + L, FM30 + A, FM30 + B, respectively). The results demonstrated that adding limonene, allicin and betaine at concentration of 0.2% to the low fish meal feed could improve final body weight, weight gain rate, and specific growth rate of M. salmoides but only in 4 weeks ( P > 0.05). Besides, dietary supplementation with attractants could significantly reduce the content of MDA in serum and liver, and increase the activity of GSH in liver ( P < 0.05). Compared with FM30 group, the supplementation with limonene, allicin or betaine diet had higher pH, redness ( a* ), yellowness ( b* ) ( P > 0.05), and lower refrigeration loss, cooking loss values ( P < 0.05). Furthermore, supplementation with attractants groups had higher values for villus height, lamina propria, crypt depth, submucous layer, and serous layer ( P < 0.05). Taken together, these results indicated that limonene, allicin and betaine had a time effect on the growth performance, and could improve antioxidant capacity, meat quality and intestinal health of M. salmoide .

Palmitoylation of MDH2 by ZDHHC18 activates mitochondrial respiration and accelerates ovarian cancer growth - Xuan Pei; Kai-Yue Li; Yuan Shen; Jin-Tao Li; Ming-Zhu Lei; Cai-Yun Fang; Hao-Jie Lu; Hui-Juan Yang; Wenyu Wen; Miao Yin; Jia Qu; Qun-Ying Lei (Science China Life Sciences, 2022)

Alterations in gut microbiota and metabolites associated with altitude-induced cardiac hypertrophy in rats during hypobaric hypoxia challenge - Zhiyuan Pan; Yichen Hu; Zongyu Huang; Ni Han; Yan Li; Xiaomei Zhuang; Jiye Yin; Hui Peng; Quansheng Gao; Wenpeng Zhang; Yong Huang; Yujun Cui; et al. (Science China Life Sciences, 2022)

Temperature has a strong impact on the abundance and community structure of comammox Nitrospira in an Ultisol - Mengmeng Feng; Zi-Yang He; Jianbo Fan; An-Hui Ge; Shengsheng Jin; Yongxin Lin; Ji-Zheng He (Journal of Soils and Sediments, 2022)

Theranostic Radiolabeled Nanomaterials for Molecular Imaging and potential Immunomodulation Effects - Chao-Cheng Chen; Yang-Hsiang Chan; Syue-Liang Lin; Huihua Kenny Chiang; Yi-Jang Lee; Hui-Yen Chuang (Journal of Medical and Biological Engineering, 2022)

Comparison of ascorbate metabolism in fruits of two jujube species with differences in ascorbic acid content - Yang Wang; Guoying Song; Dong Liang; Hui Xia; Huifen Zhang; Xian Luo; Qunxian Deng (Horticulture, Environment, and Biotechnology, 2022)

Identification of a 5-gene-risk score model for predicting luminal A-invasive lobular breast cancer survival - Yi-Huan Chen; Tao-Feng Zhang; Yi-Yuan Liu; Jie-Hua Zheng; Wei-Xun Lin; Yao-Kun Chen; Jie-Hui Cai; Juan Zou; Zhi-Yang Li (Genetica, 2022)

Genome-wide identification and expression analysis of JmjC domain–containing genes in grape under MTA treatment - Yi-Zhe Cheng; Guang-Qi He; Sheng-Di Yang; Shuai-Hui Ma; Jin-Ping Ma; Fang-Hui-Zi Shang; Xu-Fei Li; Hui-Ying Jin; Da-Long Guo (Functional & Integrative Genomics, 2022)

Direct degradation of methylene blue by unactivated peroxymonosulfate: reaction parameters, kinetics, and mechanism - Xu Zuo; Jianxin Nie; Beier Jiang; Aijun Jiang; Shiyang Zou; Junrong Wu; Bingquan Ding; Xue hui Wang; Yang Liu (Environmental Science and Pollution Research, 2022)

Heterogeneous Fenton degradation of persistent organic pollutants using natural chalcopyrite: effect of water matrix and catalytic mechanism - Jiapeng Yang; Rong Huang; Yijun Cao; Hui Wang; Andrei Ivanets; Chongqing Wang (Environmental Science and Pollution Research, 2022)

Maternal exposure to cooking oil fumes during pregnancy and autistic‐like behaviors in Chinese preschoolers - Jian-Hui Yang; Esben Strodl; Chuan-An Wu; Xiang-Yu Hou; Xiao-Na Yin; Guo-Min Wen; Deng-Li Sun; Dan-Xia Xian; Jing-Yi Chen; Ying-Jie Chen; Jing Chen; Wei-Qing Chen (Environmental Science and Pollution Research, 2022)

Characterization, source apportionment, and risk assessment of polycyclic aromatic hydrocarbons (PAHs) in urban soils from 23 cities in China - Hui Wang; Yuting Yang; Tony R. Walker; Yinggang Wang; Hao Wu; Xiaoxu Wang; Qing Luo (Environmental Science and Pollution Research, 2022)

Low Levels of Serum Zinc Associate with Malnutrition Risk Assessed by the Royal Free Hospital-Nutritional Prioritizing Tool in Cirrhosis - Wanting Yang; Xiaoyu Wang; Zihan Yu; Chaoqun Li; Mingyu Sun; Yifan Li; Yangyang Hui; Gaoyue Guo; Xiaofei Fan; Kui Jiang; Chao Sun (Biological Trace Element Research, 2022)

Finite element analysis of an all-steel buckling-restrained brace - Tao Jiang; Junwu Dai; Yongqiang Yang; Wen Bai; Hui Pang; Rongheng Liu (Earthquake Engineering and Engineering Vibration, 2022)

Gregarious larval settlement mediates the responses of new recruits of the reef coral Acropora austera to ocean warming and acidification - Lei Jiang; Yu-Yang Zhang; Cheng-Yue Liu; Lin-Tao Huang; Hao-Ya Tong; Guo-Wei Zhou; Ming-Lan Guo; Tao Yuan; Hui Huang (Frontiers in Marine Science, 2022)
Gregarious larval settlement represents an important window for chimera formation in reef corals, yet it remains largely unknown how aggregated settlement and early chimerism could modify the performance and responses of coral recruits under elevated temperature and p CO 2 . In this study, single and aggregated recruits of the broadcast spawning coral Acropora austera were exposed to contrasts of two temperatures (28 versus 30.5°C) and p CO 2 levels (~500 versus 1000 μatm) for two weeks, and algal symbiont infection success, survivorship and growth were assessed. Results showed that symbiont infection success was mainly affected by temperature and recruit type, with reduced symbiont infection at increased temperature and consistently higher infection success in chimeric recruits compared to single recruits. Furthermore, although chimeric recruits with larger areal size had significantly higher survivorship in all treatments, the polyp-specific growth rates were considerably lower in chimeric entities than individual recruits. More importantly, the recruit type significantly influenced the responses of recruit polyp-specific growth rates to elevated temperature, with chimeras exhibiting lowered skeletal lateral growth under elevated temperature. These results demonstrate the benefits and costs associated with gregarious larval settlement for juvenile corals under ocean warming and acidification, and highlight the ecological role of larval settlement behavior in mediating the responses of coral recruits to climate change stressors.

Integrated assessment of volatile organic compounds from industrial biomass boilers in China: emission characteristics, influencing factors, and ozone formation potential - Ruidan Shi; Zibing Yuan; Leifeng Yang; Daojian Huang; Hui Ma (Environmental Science and Pollution Research, 2022)

A newly characterized allele of ZmR1 increases anthocyanin content in whole maize plant and the regulation mechanism of different ZmR1 alleles - Meijie Luo; Baishan Lu; Yaxing Shi; Yanxin Zhao; Zhiyuan Wei; Chunyuan Zhang; Yuandong Wang; Hui Liu; Yamin Shi; Jinxiao Yang; Wei Song; Xiaoduo Lu; et al. (Theoretical and Applied Genetics, 2022)

Late Mesozoic rifting and its deep dynamic mechanisms in the central Sulu orogenic belt: Records from Lingshan Island - Tengfei Zhou; Yaoqi Zhou; Nina Søager; Paul Martin Holm; Zhenkai Zhang; Jun Wang; Zhao Liang; Hongyu Mu; Yanjun Cheng; Feifei Liu; Miao Wang; Yue Zhang; et al. (Science China Earth Sciences, 2022)

Clinical implementation of kVCT-guided tomotherapy with ClearRT - Bin Yang; Hui Geng; Tien Yee Amy Chang; Mei Yan Tse; Wai Wang Lam; Chen-Yu Huang; Tungho Wu; Ka Ki Lau; Kin Yin Cheung; George Chiu; Siu Ki Yu (Physical and Engineering Sciences in Medicine, 2022)

An automatic method to generate voxel-based absorbed doses from radioactivity distributions for nuclear medicine using generative adversarial networks: a feasibility study - Hui Lin; Xin Guo; Jia Jing; Xiaoli Mao; Yuanjun Yang; Min Hu (Physical and Engineering Sciences in Medicine, 2022)

Naturally-Occurring Antibodies Against Bim are Decreased in Alzheimer’s Disease and Attenuate AD-type Pathology in a Mouse Model - Jie-Ming Jian; Dong-Yu Fan; Ding-Yuan Tian; Yuan Cheng; Pu-Yang Sun; Cheng-Rong Tan; Gui-Hua Zeng; Chen-Yang He; Ye-Ran Wang; Jie Zhu; Xiu-Qing Yao; Yan-Jiang Wang; et al. (Neuroscience Bulletin, 2022)

WASHC1 interacts with MCM2-7 complex to promote cell survival under replication stress - Yu Hong; He Sun; Xian Hong; Cai-Ping Yang; Daniel D. Billadeau; Tao Wang; Zhi-Hui Deng (Molecular Biology Reports, 2022)

Two-stage hybrid network for segmentation of COVID-19 pneumonia lesions in CT images: a multicenter study - Yaxin Shang; Zechen Wei; Hui Hui; Xiaohu Li; Liang Li; Yongqiang Yu; Ligong Lu; Li Li; Hongjun Li; Qi Yang; Meiyun Wang; Meixiao Zhan; et al. (Medical & Biological Engineering & Computing, 2022)

Ecological damage of submerged macrophyte Myriophyllum spicatum by cell extracts from microcystin (MC)- and non-MC-producing cyanobacteria, Microcystis - Yunni Gao; Hui Yang; Xiaofei Gao; Mei Li; Man Zhang; Jing Dong; Jingxiao Zhang; Longfei Li; Xuejun Li; Michele A Burford (Journal of Oceanology and Limnology, 2022)

Effects of nylon mesh vitrification on the cytoskeleton, mitochondria, and aquaporins of mouse 2-cell embryos - Zhen Gao; Wei Li; Hui Zhang; Zhenshan Yang; Xiaoe Zhao; Qiang Wei; Baohua Ma (In Vitro Cellular & Developmental Biology - Animal, 2022)

Effects of tuber size and burial depth on germination and plant growth of the submerged macrophyte Vallisneria spinulosa S.Z. Yan at different light intensities - Guixiang Yuan; Lijun Sun; Peiqin Guo; Zhenglong Chen; Zhenzhi Yang; Hui Fu; Erik Jeppesen (Hydrobiologia, 2022)

Model Test Studies on Slope Supported by Bamboo Anchor and Timber Frame Beam - Xueliang Jiang; Yonghui Qian; Hui Yang; Ziqiong Xiao; Wenchen Fan; Yingbo Zhu; Wenjie Liu; Jiahui Guo (Geotechnical and Geological Engineering, 2022)

Recirculation of activated sludge for coagulant synthesis under hydrothermal conditions - Lu Wang; Dapeng Li; Xueying Li; Hui Liang; Wei Yue; Lingzhi Wang; Yang Pan; Yong Huang (Environmental Science and Pollution Research, 2022)

Xinfangfangia pollutisoli sp. nov., Isolated from Clopyralid-Contaminated Soil - Yang Mu; Jia-Yi Peng; Hui-Ping Wang; Yue Song; Hong-Mei Wang; Qing Chen; Kai Chen (Current Microbiology, 2022)

Correction to: Future precipitation changes in three key sub-regions of East Asia: the roles of thermodynamics and dynamics - Jiao Li; Yang Zhao; Deliang Chen; Yanzhen Kang; Hui Wang (Climate Dynamics, 2022)

Future precipitation changes in three key sub-regions of East Asia: the roles of thermodynamics and dynamics - Jiao Li; Yang Zhao; Deliang Chen; Yanzhen Kang; Hui Wang (Climate Dynamics, 2022)
Previous studies have projected an increase in future summer precipitation across East Asia (EA). This study investigates the relative contributions of thermodynamic and dynamic components to future precipitation changes in three key sub-regions of EA where the maximum centers of the historical precipitation are located (the tropical region, East China, and the Japan and Korea sector), and analyzes the causes of the changes in thermodynamic and dynamic components. Outputs from 30 climate models of the Coupled Model Intercomparison Project Phase 6 (CMIP6) are used. From these, the five best-performing models for historical summer precipitation climatology for EA are selected. The future summer precipitations in the three sub-regions over the near- to mid-term (2020–2069) and the long-term (2070–2095) are then examined using the multi-model ensemble mean of the five models selected (MMM05). The projections were driven by four combined scenarios of the Shared Socioeconomic Pathways (SSPs) and forcing levels of the Representative Concentration Pathways (SSP1-2.6, SSP2-4.5, SSP3-7.0, and SSP5-8.5). The results show that long-term precipitations under SSP5-8.5 are greater than those under the other scenarios across all sub-regions. After the 2070s under SSP5-8.5, a marked precipitation intensification is identified in all three sub-regions, but with different rates of increase. The projected precipitation increase is primarily attributed to the thermodynamic component, while the dynamic component related to circulation changes is relatively weak. Further analysis indicates that the pattern of the thermodynamic component in the three sub-regions is dominated by the climatological upward motion, mediated by an increase in moisture.

ZAKβ Alleviates Oxidized Low-density Lipoprotein (ox-LDL)-Induced Apoptosis and B-type Natriuretic Peptide (BNP) Upregulation in Cardiomyoblast - Yueh-Min Lin; Jiro Hasegawa Situmorang; Jia-Zun Guan; Dennis Jine-Yuan Hsieh; Jaw-Ji Yang; Michael Yu-Chih Chen; Ching-Hui Loh; Chia-Hua Kuo; Shang-Yeh Lu; Ying-Ming Liou; Chih-Yang Huang (Cell Biochemistry and Biophysics, 2022)

Three-dimensional modified pseudo-dynamic analysis of reinforced slopes with inclined soil nails - Guang-Hui Chen; Jin-Feng Zou; Tao Yang; He-Yang Shi (Bulletin of Engineering Geology and the Environment, 2022)

Improvement of the catalytic performance of glycerol kinase from Bacillus subtilis by chromosomal site-directed mutagenesis - Guanglu Wang; Mengyuan Wang; Lanxi Liu; Xiaohan Hui; Bingyang Wang; Ke Ma; Xuepeng Yang (Biotechnology Letters, 2022)

MicroRNA-223 downregulation promotes HBx-induced podocyte pyroptosis by targeting the NLRP3 inflammasome - Yani Yu; Hui Dong; Yue Zhang; Jingyi Sun; Baoshuang Li; Yueqi Chen; Moxuan Feng; Xiaoqian Yang; Shengbo Gao; Wei Jiang (Archives of Virology, 2022)

Numerical Simulation Study of the Horizontal Submerged Jet Based on the Wray–Agarwal Turbulence Model - Bo Hu; Chuan Wang; Hui Wang; Qian Yu; Jinhua Liu; Yong Zhu; Jie Ge; Xinxin Chen; Yang Yang (Journal of Marine Science and Engineering, 2022)
The horizontal submerged jet (HSJ), as a special form of jet, is widely used in aerospace, food and drug, water engineering, and other industries. In order to further understand the mechanism of the HSJ, the Wray–Agarwal turbulence model was used to predict the HSJ with different incidence heights H/D and Reynolds number (Re) conditions in this paper. The results show that the jet horizontal height H/D has a large influence on the flow field structure. The unsteady flow within the flow field is dominated by vortexes. In addition, their distribution is relatively independent of H/D. Under different H/D conditions, the axial velocity distribution of the jet has very high similarity, all of them have an obvious velocity inflection point at x = 10D. When H/D is small, the wall attachment effect of the jet and the boundary layer effect generated at the bottom of the fluid domain have a certain role in maintaining the velocity of the jet near the wall, resulting in a significantly higher axial velocity than other H/D conditions, up to 1.29 times. In this paper, we thoroughly investigated the structure of the internal flow field and velocity distribution of the submerged horizontal jet. The results have a guiding significance for engineering practice and academic research.

Coastal aquaculture farms for the sea cucumber Apostichopus japonicus provide spawning and first-year nursery grounds for wild black rockfish, Sebastes schlegelii: A case study from the Luanhe River estuary, Bohai bay, the Bohai Sea, China - Min Xu; Zun-li Qi; Zun-lei Liu; Wei-min Quan; Qi Zhao; Yun-ling Zhang; Hui Liu; Lin-lin Yang (Frontiers in Marine Science, 2022)
Aquaculture farms are known to attract wild organisms from nearby areas. Sea cucumber Apostichopus japonicus aquaculture farms in Bohai Bay, the Bohai Sea, China, might provide spawning and nursery grounds for wild black rockfish Sebastes schlegelii populations. To identify the above, we studied the variation in the numbers of S. schlegelii larvae (and length-categories as a percentage of the natural population) via ichthyoplankton surveys by months from January to October 2020, and assessed the food web structure and energy flow distribution of the farm and trophic links of S. schlegelii natural stock by using Ecopath modeling in July 2016 to August 2017. Larvae with a length between 3.90-5.80 mm were observed in the farm in May 2020, the juveniles with an estimated trophic level of 4.31. Juveniles used the farms as first-year nursery ground, and then they swam into deeper waters in August of the following year. MTI analysis showed increasing biomass of S. schlegelii might result in a decrease in the biomass of crustacea, and had positive and negative impacts on mollusk and Hexagrammos otakii biomass. We argued that aquacultural infrastructures constructed by artificial reefs could be used as a fisheries management tool to enhance S. schlegelii stocks and that monitoring of other marine organisms, such as oysters, Rapana venosa , Charybdis japonica , and Asterias spp. etc., was necessary to maintain sustainable exploitations of aquacultural farm ecosystems. A paucity of knowledge surrounding the interactions between aquaculture farms and wild organisms needs furthermore researches.

Spatial variability in the abundance and prey selection of the corallivorous snail Drupella spp. in the southeastern Hainan Island, China - Xinming Lei; Chengyue Liu; Yuyang Zhang; Xiaolei Yu; Jianhui Yang; Yong Luo; Guowei Zhou; Hui Huang (Frontiers in Marine Science, 2022)
Global climate change has caused extensive loss of biodiversity and ecosystem function globally, particularly in coral reefs in shallow tropical waters. As the corallivorous snails represent considerable disturbances to coral reefs across Indo-Pacific region, it is becoming a threat to coral health and recovery in the Hainan Island, South China Sea, but current-knowledge gap remains on the spatial distribution, prey preferences, and the influence factors related. Thus, we investigated the abundance distribution of Drupella spp. in relation to coral-prey selectivity, availability, and nutritional value. The snail density was heterogeneously distributed in the study area with an average of 0.72 ± 0.32 ind m −2 (varying from 0.09 ± 0.03 to 1.78 ± 0.39 ind m −2 ), and the snail density was found generally higher in locations with higher coral cover, which resulted in much lower density where their preferred corals became scarce. Despite the snails showing a positive preference for Acroporidae corals, they displayed dietary plasticity by changing with prey abundance and availability. Further, we found the electivity index of the coral prey related to the substrate types, and the nutritional value of prey was an additional important determinant in the prey preference, suggesting that the specific reef habitat and environmental context may alter the prey preference of Drupella spp. Combined, these results provide preliminary evidence that Drupella spp. is among the common corallivories in the reef regions of Hainan Island, and we recommend that large-scale monitoring programs assess the spatial-temporal trends to better understand the dynamics of predation linked to both anthropogenic and natural impacts.

CREB1 contributes colorectal cancer cell plasticity by regulating lncRNA CCAT1 and NF-κB pathways - Bin Li; Lisi Zheng; Jiayi Ye; Chenmin Zhang; Jie Zhou; Qiaojuan Huang; Yanhua Guo; Luqin Wang; Peng Yu; Shurong Liu; Qiao Lin; Yuxia Luo; et al. (Science China Life Sciences, 2022)

Spring snow-albedo feedback from satellite observation, reanalysis and model simulations over the Northern Hemisphere - Hui Guo; Yuting Yang (Science China Earth Sciences, 2022)

The correlation of fibrinogen-like protein-1 expression with the progression and prognosis of hepatocellular carcinoma - Nanni Hua; Anxian Chen; Chen Yang; Hui Dong; Xianglei He; Guoqing Ru; Xiangmin Tong; Feifei Zhou; Shibing Wang (Molecular Biology Reports, 2022)
Background Fibrinogen-like-protein 1 (FGL1), a member of the fibrinogen-related protein (FREP) family, is a major ligand of the immune inhibitory receptor lymphocyte-activation gene 3 (LAG-3). While FGL1 is strongly implicated in the development and prognosis of a variety of diseases, its role in hepatocellular carcinoma (HCC) is still disputed. Therefore, the role of FGL1 expression in the progression and prognosis of HCC was investigated. Methods and results In the present study, bioinformatics analysis was first used to probe the expression profile of FGL1 in multiple malignant tumor tissues and paired normal tissues, and to explore the possible relationship between FGL1 and prognosis of HCC patients. Thereafter, the expression levels of FGL1 were determined and compared in human HCC cell lines, HCC tissues, peri-tumor tissues and normal liver tissues by western blot analysis. Furthermore, tissue microarrays were used to detect the expression of FGL1 through immunohistochemical staining and to verify whether the FGL1 expression level was associated with clinicopathological features and the prognosis of HCC patients. The results showed that FGL1 was downregulated significantly in most of the HCC cells lines and HCC tissues, corresponding to the results of the bioinformatics and western blot analyses. FGL1 expression level in HCC was found to be correlated to Edmondson grade and metastasis of the HCC. Additionally, high FGL1 expression was associated with better overall survival in HCC patients, suggesting that FGL1 could function as a tumor suppressor. Conclusions The expression level of FGL1 can be correlated with the progression and prognosis of HCC, suggesting its potential as a prognostic biomarker.

miR-517b-3p promotes the progression of portal vein tumor thrombus via activating Wnt/β-catenin signaling pathway in hepatocellular carcinoma - Rui-Sheng Ke; Kun-Zhai Huang; De-sheng Bao; Jing-Rui Yang; Hua-xiang Wang; Li-Zhi Lv; Yi Jiang; Zhao-Hui Liu; Fu-Xing Zhang (Molecular Biology Reports, 2022)

Decontamination of multiple pollutants from eutrophic river water using iron-modification carbon/zeolite - Hui Ma; Yingxue Li; Defu Xu; Hanxin Tian; Hong Yang (Journal of Soils and Sediments, 2022)

The safety degree evaluation of marine biodiversity in China - Xiu-Mei Fu; Wan-Yu Wu; Fang Yang; Shan-Shan Jiang; Shi-Qi Wang; Xiao-Yan Li; Hui-Ying Tang; Ying Liu; Chang-Yun Wang (Journal of Coastal Conservation, 2022)

Dissection of valine-glutamine genes and their responses to drought stress in Arachis hypogaea cv. Tifrunner - Tian Zhang; Zicheng Wang; Yongli Zhang; Guofeng Yang; Hui Song (Functional & Integrative Genomics, 2022)

Monitoring and control methods of harmful algal blooms in Chinese freshwater system: a review - Shengjun Xu; Ping Lyu; Xiaoxu Zheng; Haijun Yang; Bing Xia; Hui Li; Hao Zhang; Shuanglong Ma (Environmental Science and Pollution Research, 2022)

Differential responses of polysaccharides and antioxidant enzymes in alleviating cadmium toxicity of tuber traditional Chinese medicinal materials - Li Yang; Yuchen Kang; Haibo Dai; Xiaoqin Wang; Mengdi Xie; Jiaxin Liu; Cheng Gao; Hui Sun; Tianqi Ao; Wenqing Chen (Environmental Science and Pollution Research, 2022)

Associations between seasonal ambient air pollution and adverse perinatal outcomes: a retrospective cohort study in Wenzhou, China - Hui-Jun Huang; Qiu-Yan Yu; Tian Zheng; Shan-Shan Wang; Xin-Jun Yang (Environmental Science and Pollution Research, 2022)

Pollution assessment, source identification, and health risks of heavy metals: a case study in a typical wheat–maize rotation area of eastern China - Fang Wan; Yongbo Teng; Xiuwen Zhang; Linsong Yu; Hong Pan; Hui Wang; Quangang Yang; Yanhong Lou; Yuping Zhuge (Environmental Geochemistry and Health, 2022)

Altered effective connectivity within the cingulo-frontal-parietal cognitive attention networks in chronic low back pain: a dynamic causal modeling study - Cui Ping Mao; Hua Juan Yang; Qiu Juan Zhang; Quan Xin Yang; Xiao Hui Li (Brain Imaging and Behavior, 2022)

Optical Characteristics of Chromophoric Dissolved Organic Matter (CDOM) in Upstream and Downstream Lakes of Taihu Lake Basin: New Insights for Water Environmental Management - Weixiang Ren; Xiaodong Wu; Bingfa Chen; Jianying Chao; Xuguang Ge; Jiuyun Yang; Hui Yang (Chinese Geographical Science, 2022)

The effects of dietary fermented wheat bran polysaccharides on mucosal and serum immune parameters, hepatopancreas antioxidant indicators, and immune-related gene expression of common carp (Cyprinus carpio) juveniles - Rui-Fang Wang; Yuan Wang; Jun Zhang; Mei-Qi Weng; Yu-Hui Liu; Qiu-Yan Cheng; Min Song; Yan-Ping Yang; Xiao-Ping An; Jing-Wei Qi (Aquaculture International, 2022)

Seasonal soil-plant nitrogen dynamics of a cordgrass salt marsh in response to coastal embankments in Eastern China - Ge Qin; Hongyu Feng; Hui Zhao; Lu Xia; Wen Yang; Yongqiang Zhao; Nasreen Jeelani; Shuqing An (Frontiers in Marine Science, 2022)
The effects of coastal embankments on nitrogen (N) cycling in the Spartina alterniflora salt marsh have been extensively reported. However, it remains unclear effects of the embankment on the sizes of diverse N subpools in the plant-soil subsystems year-round. This study examined seasonal changes in various N subpools of plant subsystems; soil subsystems [e.g., soil organic N (SON), recalcitrant organic N (RON), labile organic N (LON), dissolved organic N (DON), ammonium N(NH+4 N), and nitrate N(NO3-N)]; N mineralization [e.g., soil net ammonification (R A ) and nitrification (R N ) rate]; and immobilization [e.g., microbial biomass N (MBN)] in embanked and adjacent S. alterniflora natural salt marshes on the coast of Eastern China. The embankment significantly reduced the litter N storage by 62.7–71.8% over the four seasons and decreased the root N storage by 53.0% during winter. The SON, LON, RON, and N H +4 N concentrations declined significantly by 43.0–60.2%, 35.8–64.8%, 44.9–59.0%, and 20.8–42.2%, respectively, over the four seasons following the embankment construction. Furthermore, the embankment dramatically reduced the DON concentrations by 21.9% in spring, 14.6% in summer, and 10.4% in winter, while notably diminishing the NO3 N concentrations by 33.4% in autumn and 44.9% in winter, and the R A and R N in spring and summer. However, the embankment clearly increased the MBN concentrations during summer and autumn, the NO3 N concentrations in spring, and the R A and R N in winter at different levels. Due to the decreased soil N inputs from plants, the embankment decreased the organic and inorganic N subpools every season to varying degrees, except for the NO3 N concentration in spring. We suggest that the decreased soil salinity following embankment establishment might increase the uptake of ions by microbes, while stimulating the production of MBN. Ultimately, the NO3 N and DON were two vital N sources for S. alterniflora , and plants absorbed N from the soil to promote their biomass, as well as N concentration and storage. This study is conducive toward understanding the mechanisms behind the effects of coastal embankments on the N transfer among various N subpools in the plant and soil systems.

Long non-coding RNA LBX2-AS1 predicts poor survival of colon cancer patients and promotes its progression via regulating miR-627-5p/RAC1/PI3K/AKT pathway - Jing Fang; Junyuan Yang; Hui Chen; Wen Sun; Lingyun Xiang; Jueping Feng (Human Cell, 2022)

BrKAO2 mutations disrupt leafy head formation in Chinese cabbage (Brassica rapa L. ssp. pekinensis) - Shengnan Huang; Yue Gao; Meihui Xue; Junjie Xu; Ruiqi Liao; Shayu Shang; Xiaofei Yang; Yonghui Zhao; Chengyu Li; Zhiyong Liu; Hui Feng (Theoretical and Applied Genetics, 2022)

Dogs lacking Apolipoprotein E show advanced atherosclerosis leading to apparent clinical complications - Hui Zhao; Jianping Zhao; Di Wu; Zhaolin Sun; Yang Hua; Min Zheng; Yumei Liu; Qi Yang; Xiahe Huang; Yuan Li; Yueshan Piao; Yingchun Wang; et al. (Science China Life Sciences, 2022)

Characterization and comparison of two C-type lectins with novel key motifs from mud crab Scylla paramamosain - Boxin Zeng; Taiwei Dong; Yanting Xia; Shun Yang; Mengmeng Huang; Hui Fei (Journal of Oceanology and Limnology, 2022)

Nitrogen-Doped and Surface Functionalized CDs: Fluorescent Probe for Cellular Imaging and Environmental Sensing of ClO– - Tiantian Xu; Hui Li; Haonan Yang; Zheng Yang; Xiaodan Jia; Shunsheng Zhao; Zaiwen Yang; Xiangrong Liu (Journal of Fluorescence, 2022)

Association between secondhand smoke and peripheral arterial disease: a meta-analysis of cross-sectional studies - Chih-Wei Wu; Hung-Yi Chuang; Kazuhiro Watanabe; Pei-Shan Wu; Hui-Chen Pan; Chao-Ling Wang; Chen-Cheng Yang; Chih-Hsing Hung; Chia-Yen Dai; Chi-Kung Ho; Norito Kawakami (International Archives of Occupational and Environmental Health, 2022)

Acetylsalicylic acid (ASA) suppressed Fusarium rot development and neosolaniol (NEO) accumulation by activating phenylpropane metabolism in muskmelon fruit - Lan Li; Qili Liu; Huali Xue; Yang Bi; Hussain Raza; Rui Zhang; Jimdjio Kouasseu Carelle; Hui Peng; Haitao Long; Dov Prusky (European Journal of Plant Pathology, 2022)

Effects of the soaking-related parameters in a combined freezing-based seawater desalination process - Hui Yang; Yuanfei Jiang; Rui Wang; Bingyan Dong; Mengxiao Fu (Environmental Science and Pollution Research, 2022)

Quantification of industrial wastewater discharge from the major cities in Sichuan province, China - Hui Guo; Yawen Zhang; Zhen’an Yang (Environmental Science and Pollution Research, 2022)

Bioleaching Performance of Titanium from Bauxite Residue Under a Continuous Mode Using Penicillium Tricolor - Yang Qu; Hui Li; Ben Shi; Hannian Gu; Guangxuan Yan; Zipeng Liu; Ruizhi Luo (Bulletin of Environmental Contamination and Toxicology, 2022)

High Levels of 25-OH-Vitamin D and Copper in Pregnant Women with Abnormal Glucose Challenge Test - Chien-Hua Chiang; Wan-Ju Kung; Chien-Hung Lee; Yeong-Hwa Zen; Cheng-Fa Lee; Hui-Ru Yang; Ching-Chiang Lin; Yeou-Lih Huang (Biological Trace Element Research, 2022)

Quantifying soil nitrous oxide emissions in spring freezing-thawing period over different vegetation types in Northeast China - Bin Wu; Chang-cheng Mu; Hui Liu; Ya-kun Xu; Yue Zhang; Jia-shuo Yang; Wen-nian Xu (Journal of Mountain Science, 2022)

Analytical model for prediction of volumetric fracture propagation morphology considering elastoplasticity - Yuxuan Liu; Xinggui Yang; Jianchun Guo; Hui Liu; Shengjie Li; Dengqiang Hu (Arabian Journal of Geosciences, 2022)

Semisolid Extrusion 3D Printing of Propranolol Hydrochloride Gummy Chewable Tablets: an Innovative Approach to Prepare Personalized Medicine for Pediatrics - Chunxiao Zhu; Yang Tian; Enhui Zhang; Xiang Gao; Hui Zhang; Nan Liu; Xiaolu Han; Yong Sun; Zengming Wang; Aiping Zheng (AAPS PharmSciTech, 2022)

Astragaloside IV improved antioxidative stress capacity and related gene expression of the Keap1‐Nrf2 pathway in grass carp ( Ctenopharyngodon idella ) hepatocytes under heat stress - Hua Liu; Ying Yang; Ying‐Ying Yu; Jing‐Jing Feng; Xiao‐Xue Bao; Jun Zhao; Hui Yu (Journal of Fish Biology, 2022)
This study aims to investigate the protective effects of astragaloside IV (AS‐IV) on the hepatocytes of grass carp ( Ctenopharyngodon idella ) on heat stress. Cultured cells were treated with AS‐IV (0, 50, 100 and 200 μg/ml) at 28°C for 24 h and then exposed to heat stress by increasing the culturing temperature (32 ± 0.5°C) for 6 h. The increased temperatures significantly reduced cell viability and superoxide dismutase (SOD) activity, and increased malondialdehyde (MDA) levels in the 0 μg/ml AS‐IV treatment group at 32°C, but the grass carp hepatocytes treated with 100 and 200 μg/ml AS‐IV had significantly increased cell viability and SOD activity and decreased MDA levels. The mRNA levels of keap1a , keap1b , nrf2 , gsh‐px , cat , cu‐zn sod , mgst1 and il‐6 were significantly lower in the 0 μg/ml AS‐IV treatment group at 32°C, while those of keap1a , nrf2 , gsh‐px , cat , cu‐zn sod , gstp1 , ho‐1 and il‐6 were significantly higher in cells treated with 100 or 200 μg/ml AS‐IV. Our findings indicate that AS‐IV could enhance the antioxidative stress capacity of grass carp hepatocytes under heat stress, and its mechanism may be associated with the activation of the Keap1‐Nrf2 pathway. Thus, these results provide new insights into how to alleviate heat stress in grass carp.

The tetrameric assembly of 2‐aminomuconic 6‐semialdehyde dehydrogenase is a functional requirement of cofactor NAD + binding - Qiuli Shi; Yanjuan Chen; Xinxin Li; Hui Dong; Cheng Chen; Zhihui Zhong; Cheng Yang; Guangfeng Liu; Dan Su (Environmental Microbiology, 2022)
Summary The bacterium Pseudomonas sp. AP‐3 is able to use the environmental pollutant 2‐aminophenol as its sole source of carbon, nitrogen, and energy. Eight genes (amnA, B, C, D, E, F, G, and H) encoding 2‐aminophenol metabolizing enzymes are clustered into a single operon. 2‐Aminomuconic 6‐semialdehyde dehydrogenase (AmnC), a member of the aldehyde dehydrogenase (ALDH) superfamily, is responsible for oxidizing 2‐aminomuconic 6‐semialdehyde to 2‐aminomuconate. In contrast to many other members of the ALDH superfamily, the structural basis of the catalytic activity of AmnC remains elusive. Here, we present the crystal structure of AmnC, which displays a homotetrameric quaternary assembly that is directly involved in its enzymatic activity. The tetrameric state of AmnC in solution was also presented using small‐angle X‐ray scattering. The tetramerization of AmnC is mediated by the assembly of a protruding hydrophobic beta‐strand motif and residues V121 and S123 located in the NAD + ‐binding domain of each subunit. Dimeric mutants of AmnC dramatically lose NAD + binding affinity and failed to oxidize the substrate analogue 2‐hydroxymuconate‐6‐semialdehyde to α‐hydroxymuconic acid, indicating that tetrameric assembly of AmnC is functional requirement.

Retraction Note to: Long non-coding RNA MIAT promotes the growth of melanoma via targeting miR-150 - Lifei Zhu; Yexiao Wang; Chaoying Yang; Yanchang Li; Zhixin Zheng; Liangcai Wu; Hui Zhou (Human Cell, 2022)

Experimental study on the acoustic emission response and permeability evolution of tunnel lining concrete during deformation and failure - Linken Shi; Hui Zhou; Yang Gao; Jingjing Lu; Qiantao Li (European Journal of Environmental and Civil Engineering, 2022)

Effects of Dietary Nano-Curcumin Supplementation on Growth Performance, Glucose Metabolism, and Endoplasmic Reticulum Stress in Juvenile Largemouth Bass, Micropterus salmoides - Xiaoxue Bao; Mingshi Chen; Yuhua Yue; Hua Liu; Ying Yang; Hui Yu; Yingying Yu; Ning Duan (Frontiers in Marine Science, 2022)
This study evaluated the effects of nano-curcumin on growth performance, mucosal immunity, antioxidant response, glucose metabolism, and endoplasmic reticulum stress in largemouth bass. Three groups (three replicates/group) of 270 fish with the mean body weight of 7.00 ± 0.02 g were fed with diets containing 0% (control), 0.1%, and 0.2% nano-curcumin for 60 days. The results showed that dietary supplementation of nano-curcumin had no significant effects on the growth performance, body composition, lysozyme (LYZ), and alkaline phosphatase (AKP) in skin mucus, superoxide dismutase (SOD), and catalase (CAT) activity in serum of largemouth bass. However, dietary supplementation with 0.2% nano-curcumin significantly increased peroxidase (POD) activity in skin mucus and decreased the serum MDA activity compared with the control group. Moreover, dietary supplementation of 0.2% nano-curcumin significantly decreased the levels of serum glucose and liver glycogen, which may be mainly related to the increased gene expression of glucose transporter 2 ( GLUT2 ), glucokinase ( GK ), phosphofructokinase ( PFK ), and pyruvate kinase ( PK ). At the same time, the hepatic gene expression of glucose-regulated protein78 ( GRP78 ), activating transcription factor6 ( ATF6 ), inositol-requiring enzyme 1 ( IRE ), and eukaryotic initiation factor 2α ( eIF2α ) in the 0.2% nano-curcumin group were rapidly suppressed, indicating that adding 0.2% nano-curcumin to the diet can alleviate endoplasmic reticulum stress (ERS) in fish. In conclusion, diets supplemented with 0.2% nano-curcumin effectively improved mucosal immunity, antioxidant properties, and glucose metabolism and alleviated ERS induced by long-term carbohydrate intake in largemouth bass.

Hasubanan alkaloids with anti-inflammatory activity from Stephania longa - Hui Liu; Wan-Qin Liao; Rong-Xiao Lin; Lixia Fan; Jinyan Sun; Hong-Yuan Chen; Fang Liu; An-Ping Yang (Natural Product Research, 2022)

Otolith Marking With Strontium for Stock Assessment in Coilia nasus - Ming-Zhi Liu; Ri-jin Jiang; Hui Zhang; Fan Yang; Xia-Fang Li; Guang-Peng Feng; Rui Yin; Feng Chen (Frontiers in Marine Science, 2022)
Mass stock enhancement and release are excellent ways to recover Coilia nasus resources. However, it is challenging to evaluate stock enhancement effectively, and it is important to establish a method suitable for estimating C. nasus populations. We explored the effectiveness of marking otoliths in these fish with strontium by immersing C. nasus in hexahydrate strontium chloride solutions. We used laser ablation inductively coupled plasma mass spectrometry to measure the strontium content of otoliths and fish bodies. The larvae (40 d post hatch) were reared in five different concentrations of strontium (0, 12, 24, 48, and 60 mg/L) for 7 d, followed by treatment in non-additive water for 3 wk. The results showed that the cumulative mortality rate was not significantly different between treatment and control groups ( P >0.05), except in the group treated with 24 mg/L strontium. The swimming and feeding behaviors did not change significantly, indicating that strontium did not negatively affect survival in this species. The strontium/calcium ratios of otoliths in the control group were stable (1.78–2.32 mmol/mol), whereas those of the experimental (marked) groups ranged widely (4.47–61.02 mmol/mol). The strontium/calcium ratios increased with increasing strontium concentration, but gradually returned to baseline values, resulting in a 100% success rate of marking with strontium. Following immersion in 12 mg/L strontium, strontium levels in the body returned to normal after 24 d. In summary, a treatment of 12 mg/L strontium for 4 d was identified as viable for marking. We confirmed the feasibility of strontium marking for the mass marking and release of C. nasus . This marking method does not affect the physiology of the fish and may provide a new approach for reasonable and scientific stock assessment of C. nasus post hatch.

Screening of Upstream Transcript Factors of IbMYB1-1 by Yeast One-hybrid in Purple-fleshed Sweet Potato - Danwen Fu; Yake Hui; Yahui Chen; Shaohua Yang; Feng Gao (Tropical Plant Biology, 2022)

Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities - Lu Luo; Jun Yang; Cheng Wang; Jie Wu; Yafang Li; Xu Zhang; Hui Li; Hui Zhang; Yumei Zhou; Aiping Lu; Shilin Chen (Science China Life Sciences, 2022)

Mechanical Properties and Deterioration Mechanism of Remolded Carbonaceous Mudstone Exposed to Wetting–Drying Cycles - Yu-Ling Yang; Tao Zhang; Song-Yu Liu; Jun-Hui Luo (Rock Mechanics and Rock Engineering, 2022)

Screening of Lactic Acid Bacterial Strains with Antiviral Activity Against Porcine Epidemic Diarrhea - Yang-Ming Chen; Aniket Limaye; Hui-Wen Chang; Je-Ruei Liu (Probiotics and Antimicrobial Proteins, 2022)

Land use effects on gross soil nitrogen transformations in karst desertification area - Hui Yang; Farzaneh Garousi; Jun Wang; Jianhua Cao; Xingliang Xu; Tongbin Zhu; Christoph Müller (Plant and Soil, 2022)

The fate of drought-related genes after polyploidization in Arachis hypogaea cv. Tifrunner - Yongli Zhang; Maofeng Chai; Xiaojun Zhang; Guofeng Yang; Xiang Yao; Hui Song (Physiology and Molecular Biology of Plants, 2022)

An automatic approach for heart failure typing based on heart sounds and convolutional recurrent neural networks - Hui Wang; Xingming Guo; Yineng Zheng; Yang Yang (Physical and Engineering Sciences in Medicine, 2022)

The Effect of Cognitive Intervention on Cognitive Function in Older Adults With Alzheimer’s Disease: A Systematic Review and Meta-Analysis - Yun-Yun Wang; Liang Yang; Jing Zhang; Xian-Tao Zeng; Yang Wang; Ying-Hui Jin (Neuropsychology Review, 2022)

Extracellular vesicles derived from human Sertoli cells: characterizations, proteomic analysis, and miRNA profiling - Xiao-Hui Tan; Sheng-Ji Gu; Wen-Jie Tian; Wen-Peng Song; Yang-Yang Gu; Yi-Ming Yuan; Xue-Song Li; Zhong-Cheng Xin; Sae Woong Kim; Rui-Li Guan; Woong Jin Bae (Molecular Biology Reports, 2022)

Association between MAP3K4 gene polymorphisms and the risk of schizophrenia susceptibility in a Northeast Chinese Han population - Yang Sun; Ye Lv; Hui-Wen Ren; Guan-Yu Wang; Li-Na Xuan; Yi-Yang Luo; Zhi-Lin Luan (Metabolic Brain Disease, 2022)

Long-term exercise pre-training attenuates Alzheimer’s disease–related pathology in a transgenic rat model of Alzheimer’s disease - Luodan Yang; Chongyun Wu; Yong Li; Yan Dong; Celeste Yin-Chieh Wu; Reggie Hui-Chao Lee; Darrell W. Brann; Hung Wen Lin; Quanguang Zhang (GeroScience, 2022)

Contribution of recycled moisture to precipitation and its influencing factors in the subalpine zone of Qilian Mountains - Miaomiao Zhang; Wenxiong Jia; Guofeng Zhu; Yang Shi; Zhiyuan Zhang; Hui Xiong; Le Yang; Fuhua Zhang (Environmental Science and Pollution Research, 2022)

Mixed carbonate-siliciclastic reservoir characterization and hydrocarbon accumulation process of the Ganchaigou area in the western Qaidam Basin, Tibet Plateau - Hai Wu; Hui Liu; Long Wang; Lili Gui; Cheng Yang; Lixin Wang (Carbonates and Evaporites, 2022)

Shear behavior of sliding zone soil of loess landslides via ring shear tests in the South Jingyang Plateau - Rongsen Zhu; Wan-li Xie; Qiqi Liu; Hui Yang; Qiyao Wang (Bulletin of Engineering Geology and the Environment, 2022)
Since the 1970s, a large number of loess collapses and landslides have occurred in the Loess Plateau of China due to water diversion and irrigation projects. A large amount of ancient landslide deposits are accumulated at the foot of the tableland, which is likely to slide again in the case of a rapid increase in short-term rainfall or long-term irrigation. The weak characteristics of the sliding zone soil often become the key factor affecting the revival of old landslides. To explore the effects of water content and shear rate on shear behavior of the sliding zone soil, a series of ring shear tests were conducted on reconstituted loess in the South Jingyang Plateau. Experimental results suggest that under the condition of normal consolidation, the soil sample with the optimum moisture content has the highest shear strength. The increase in the shear rate effectively reduces the strength of the soil. Because of the high shear rate, the pore water that cannot be dissipated and fine particles accumulated at the shear plane form a weak base (slurry making theory), which cannot be easily stopped once the landslides start, leading to high-speed and long-distance landslides. In addition, the changes in the soil particles and pores were observed using a scanning electron microscope (SEM), and the observations were consistent with macroscopic results. From these studies, we come to the conclusion that the motion mechanism of reactivated landslide was associated with the interaction of water content and shear rate, which reduces the shear strength of the displaced materials to a great extent.

Neorhizobium xiangyangii sp. nov., isolated from a highland barley cultivation soil in Qamdo, Tibet - Hu Pan; Zi-Qiong Zhou; Guo-Wei He; Jie Zhou; Kai Jin; Hu-Hu Liu; Chong Wang; Hui Yang; Yao-Bin Yu; Yun Tian (Archives of Microbiology, 2022)

Study on the synergistic operation characteristics of disc cutter with the assistance of other rock-breaking methods - Hui Zhou; Futong Xu; Jingjing Lu; Yang Gao; Jiancheng Xiao; Hongliang Tu (Arabian Journal of Geosciences, 2022)

Tensor discriminant dictionary classification method for prestack seismic reflection patterns - Han-Peng Cai; Peng Jing; Jun-Hui Yang (Applied Geophysics, 2022)

Intelligent identification method and application of seismic faults based on a balanced classification network - Jing Yang; Ren-Wei Ding; Hui-Yong Wang; Nian-Tian Lin; Li-Hong Zhao; Shuo Zhao; Yu-Jie Zhang (Applied Geophysics, 2022)

Geochemistry and geochronology of early Palaeozoic seamount in Western Kunlun orogenic belt and the tectonic implications - Chen Yang; Yunpeng Dong; Hui Wang; Zhongyue Lin; Youyun Liao; Shangpeng Zhang; Huan Liu (International Geology Review, 2022)

Phenolic compounds from the sclerotia of Inonotus obliquus - Yan-Mei Wei; Li Yang; Wen-Li Mei; Hui-Qin Chen; Cai-Hong Cai; Wei Li; Wen-Hua Dong; Zhi-Bao Chen; Hao-Fu Dai (Natural Product Research, 2022)

Long-term fertilization effects on soil biotic communities are mediated by plant diversity in a Tibetan alpine meadow - Peng Wang; Fei Yang; Xiaoyun Chen; Junyong Li; Xianhui Zhou; Hui Guo (Plant and Soil, 2022)

Intragastric safflower yellow and its main component HSYA improve leptin sensitivity before body weight change in diet-induced obese mice - Xiaorui Lyu; Kemin Yan; Hanyuan Xu; Huijuan Zhu; Hui Pan; Linjie Wang; Hongbo Yang; Fengying Gong (Naunyn-Schmiedeberg's Archives of Pharmacology, 2022)

The level of endogenous JA is critical for activation of SA- and JA-defensive signaling pathway in japonica rice cultivar Ziyu44 upon Magnaporthe oryzae infection - Xingyu An; Hui Zhang; Jinlu Li; Rui Yang; Qianchun Zeng; Mo Wang; Qiong Luo (Journal of Plant Pathology, 2022)

Two new dammarane-type triterpenoids from the green walnut husks of Juglans mandshurica Maxim - Yuan-Yuan Zhou; Hui-Rui Gao; Hong-Juan Song; Dan-Da Ma; Xiao-Juan Zhang; Yan-Ping Sun; Yan Liu; Xiao-Li Wang; Bing-You Yang; Hai-Xue Kuang (Natural Product Research, 2022)

Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide - Ting Jiang; Geng Xia; Bo Yang; Hong-wei Zhang; Yue-shan Yin; Cheng-wei Tang; Jin-hui Yang (Tissue Engineering and Regenerative Medicine, 2022)
Background: Endotoxemia is related to worse clinical outcomes in acute liver failure (ALF), but its management remains unsatisfactory. In this study, we aimed to assess whether the application of bone marrow mesenchymal stem cells (BMSCs) could eliminate endotoxemia and protect rats against ALF induced by thioacetamide (TAA). Methods: BMSCs were isolated from rats and identified by the specific morphology, differentiation potential, and surface markers. The optimal dose of TAA for this study was explored and TAA-induced ALF rats were randomized to three groups: the normal control group (Saline), ALF group (TAA + Saline), and BMSCs-treated group (TAA + BMSCs). The intestinal migration and differentiation of BMSCs was tracked in vivo , and intestinal permeability, endotoxin and inflammatory cytokines, histology, and mortality were analyzed. Moreover, we added the inhibitor of the PI3K/AKT/mTOR signaling pathway into the co-culture system of BMSCs with enterocytes and then performed CK and Villin expression experiments to assess the role of PI3K/AKT/mTOR signal pathway in the intestinal differentiation of BMSCs. Results: BMSCs migrated to the intestinal injury sites and differentiated into enterocytes, intestinal permeability was decreased compared with the ALF group. The higher expression of endotoxin and inflammatory cytokines were reversed after BMSCs transplantation in rats with ALF. Mortality and intestinal lesion were significantly decreased. Blocking the PI3K/AKT/mTOR signal pathway inhibited BMSCs’ intestinal differentiation in vitro . Conclusion: BMSCs can eliminate endotoxemia and reduce mortality in rats with ALF, and the PI3K/AKT/mTOR signal pathway is involved in intestinal differentiation. BMSCs transplantation could be a potential candidate for the treatment of endotoxemia in ALF.

Moment Tensor Inversion and Stress Evolution of Coal Pillar Failure Mechanism - Chun-Hui Song; Cai-Ping Lu; Xiu-Feng Zhang; Chao Wang; Hua-Dong Xie; Xian-Yang Yan; Hong-Wei Yang (Rock Mechanics and Rock Engineering, 2022)

Correction to: Detection of Coal Spontaneous Combustion Using the TEM Method: A Synthetic Study - Zhejian Hui; Yunhe Liu; Changchun Yin; Yang Su; Xiuyan Ren; Bo Zhang; Bin Xiong (Pure and Applied Geophysics, 2022)

Anterior Cingulate Cortex Mediates Hyperalgesia and Anxiety Induced by Chronic Pancreatitis in Rats - Dan Ren; Jia-Ni Li; Xin-Tong Qiu; Fa-Ping Wan; Zhen-Yu Wu; Bo-Yuan Fan; Ming-Ming Zhang; Tao Chen; Hui Li; Yang Bai; Yun-Qing Li (Neuroscience Bulletin, 2022)
Central sensitization is essential in maintaining chronic pain induced by chronic pancreatitis (CP), but cortical modulation of painful CP remains elusive. Here, we examined the role of the anterior cingulate cortex (ACC) in the pathogenesis of abdominal hyperalgesia in a rat model of CP induced by intraductal administration of trinitrobenzene sulfonic acid (TNBS). TNBS treatment resulted in long-term abdominal hyperalgesia and anxiety in rats. Morphological data indicated that painful CP induced a significant increase in FOS-expressing neurons in the nucleus tractus solitarii (NTS) and ACC, and some FOS-expressing neurons in the NTS projected to the ACC. In addition, a larger portion of ascending fibers from the NTS innervated pyramidal neurons, the neural subpopulation primarily expressing FOS under the condition of painful CP, rather than GABAergic neurons within the ACC. CP rats showed increased expression of vesicular glutamate transporter 1, and increased membrane trafficking and phosphorylation of the N -methyl-D-aspartate receptor (NMDAR) subunit NR2B and the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) subunit GluR1 within the ACC. Microinjection of NMDAR and AMPAR antagonists into the ACC to block excitatory synaptic transmission significantly attenuated abdominal hyperalgesia in CP rats, which was similar to the analgesic effect of endomorphins injected into the ACC. Specifically inhibiting the excitability of ACC pyramidal cells via chemogenetics reduced both hyperalgesia and comorbid anxiety, whereas activating these neurons via optogenetics failed to aggravate hyperalgesia and anxiety in CP rats. Taken together, these findings provide neurocircuit, biochemical, and behavioral evidence for involvement of the ACC in hyperalgesia and anxiety in CP rats, as well as novel insights into the cortical modulation of painful CP, and highlights the ACC as a potential target for neuromodulatory interventions in the treatment of painful CP.

Soil phosphorus availability and stoichiometry determine microbial activity and functional diversity of fluvo-aquic soils under long-term fertilization regimes - Wei He; Wenhua Ye; Mingjie Sun; Yaping Li; Manman Chen; Meng Wei; Guoqing Hu; Quangang Yang; Hong Pan; Yanhong Lou; Hui Wang; Yuping Zhuge (Journal of Soils and Sediments, 2022)

Localization of QTL for cold tolerance at the germination stage of rice (Oryza sativa L.) using recombinant inbred lines - Liangzi Cao; Shukun Jiang; Guohua Ding; Tongtong Wang; Liangming Bai; Jinsong Zhou; Yu Luo; Tianshu Xia; Hui Jiang; Kai Liu; Xueyang Wang; Guang Yang; et al. (Genetic Resources and Crop Evolution, 2022)
The cold tolerance of germinating direct-sown rice ( Oryza sativa L.) has an increased rate of emergence, which ensures vigorous seedling growth. Research on QTL localization for cold tolerance at the germination stage can assist in molecular marker-assisted selection and enhance breeding efficiency. In this study, 94 populations of recombinant self-incompatible lines from Heigu and Ha 9366 were selected to investigate germination rates at low temperatures. It was found that two QTL loci (qLTG-3 and qLTG-12) were located at different germination times on chromosomes 3 and 12, respectively. The two QTLs at three different germination times, located using QTL, accounted for 21.3–25.9% of the phenotypic variation. Moreover, a reciprocal effect was detected between the two QTLs. The double QTLs increased the germination rate by 22–27% in this population. Additionally, qLTG-12 improved cold tolerance at the seedling stage. The results of this study might provide the materials and molecular markers for future molecular marker-assisted breeding for cold tolerance at the germination stage.

Pseudomonas simiae augments the tolerance to alkaline bauxite residue in Atriplex canescens by modulating photosynthesis, antioxidant defense enzymes, and compatible osmolytes - Ben Shi; Yang Qu; Hui Li; Minghui Wan; Jiayu Zhang (Environmental Science and Pollution Research, 2022)

Norovirus detection in wastewater and its correlation with human gastroenteritis: a systematic review and meta-analysis - Yue Huang; Nan Zhou; Shihan Zhang; Youqin Yi; Ying Han; Minqi Liu; Yue Han; Naiyang Shi; Liuqing Yang; Qiang Wang; Tingting Cui; Hui Jin (Environmental Science and Pollution Research, 2022)

Effect of the Grain for Green Project on freshwater ecosystem services under drought stress - Hui-qing Han; Jian-qiang Yang; Yue Liu; Ying-jia Zhang; Jun-wen Wang (Journal of Mountain Science, 2022)

Investigation on grouting diffusion in inclined fracture with flowing water conditions - Jia-fan Zhang; Xun-xun Chen; Yang Liu; Hui-mei Zhang; Chun-lin Wang; Gang Fang (Arabian Journal of Geosciences, 2022)

Alexandriicola marinus gen. nov., sp. nov., a new member of the family Rhodobacteraceae isolated from marine phycosphere - Wen-Zhuo Zhu; Hui-Min Gao; Ya-Ming Ge; Jun Dai; Xi Yang; Xiao-Ling Zhang; Qiao Yang (Antonie van Leeuwenhoek, 2022)

The Predictability of Ocean Environments that Contributed to the 2020/21 Extreme Cold Events in China: 2020/21 La Niña and 2020 Arctic Sea Ice Loss - Fei Zheng; Ji-Ping Liu; Xiang-Hui Fang; Mi-Rong Song; Chao-Yuan Yang; Yuan Yuan; Ke-Xin Li; Ji Wang; Jiang Zhu (Advances in Atmospheric Sciences, 2022)
Several consecutive extreme cold events impacted China during the first half of winter 2020/21, breaking the low-temperature records in many cities. How to make accurate climate predictions of extreme cold events is still an urgent issue. The synergistic effect of the warm Arctic and cold tropical Pacific has been demonstrated to intensify the intrusions of cold air from polar regions into middle-high latitudes, further influencing the cold conditions in China. However, climate models failed to predict these two ocean environments at expected lead times. Most seasonal climate forecasts only predicted the 2020/21 La Niña after the signal had already become apparent and significantly underestimated the observed Arctic sea ice loss in autumn 2020 with a 1–2 month advancement. In this work, the corresponding physical factors that may help improve the accuracy of seasonal climate predictions are further explored. For the 2020/21 La Niña prediction, through sensitivity experiments involving different atmospheric–oceanic initial conditions, the predominant southeasterly wind anomalies over the equatorial Pacific in spring of 2020 are diagnosed to play an irreplaceable role in triggering this cold event. A reasonable inclusion of atmospheric surface winds into the initialization will help the model predict La Niña development from the early spring of 2020. For predicting the Arctic sea ice loss in autumn 2020, an anomalously cyclonic circulation from the central Arctic Ocean predicted by the model, which swept abnormally hot air over Siberia into the Arctic Ocean, is recognized as an important contributor to successfully predicting the minimum Arctic sea ice extent.

Global divergent trends of algal blooms detected by satellite during 1982–2018 - Chong Fang; Kaishan Song; Hans W Paerl; Pierre‐Andre Jacinthe; Zhidan Wen; Ge Liu; Hui Tao; Xiaofeng Xu; Tiit Kutser; Zongming Wang; Hongtao Duan; Kun Shi; et al. (Global Change Biology, 2022)
Algal blooms (ABs) in inland lakes have caused adverse ecological effects, and health impairment of animals and humans. We used archived Landsat images to examine ABs in lakes (>1 km 2 ) around the globe over a 37‐year time span (1982–2018). Out of the 176032 lakes with area >1 km 2 detected globally, 863 were impacted by ABs, 708 had sufficiently long records to define a trend, and 66% exhibited increasing trends in frequency ratio (FRQR, ratio of the number of ABs events observed in a year in a given lake to the number of available Landsat images for that lake) or area ratio (AR, ratio of annual maximum area covered by ABs observed in a lake to the surface area of that lake), while 34% showed a decreasing trend. Across North America, an intensification of ABs severity was observed for FRQR ( p p p p

Structure, antioxidant property and protection on PC12 of a polysaccharide isolated and screened from Abelmoschus esculentus L.Moench (okra) - Li-Chao Pan; Yang-Yang Sun; Xiao-Ling Zhang; Zhen-Yuan Zhu; Chun-Yu Liu; Hui-Qing Sun; Xue-Qing Geng; Wei Jiang; Jia-He Wang (Natural Product Research, 2022)

Anti-inflammatory constituents from Phyllostachys makinoi Hayata - Chia-Ching Liaw; Yu-Chi Lin; Shao-Yu Wu; Jenny Chun-Ling Kuo; Zhi-Hu Lin; Kai-Wei Lin; Huang Hui-Chi; Li-Ming Yang Kuo; Yao-Haur Kuo (Natural Product Research, 2022)

Three new 3-formyl-2-arylbenzofurans from Itea yunnanensis and their anti-hepatocellular carcinoma effects - Tian-Qiong Lang; Guo-Yong Luo; Wen-Chen Pu; Zhi-Wei Wang; Jian Wang; Xiao-Long Tian; Pan Zhang; Neng-Wu Zhao; Wu-De Yang; Hui-Fang Chai (Natural Product Research, 2022)

Effects of roasting and deodorisation on 3-monochloropropane-1, 2-diol esters, 3, 4-benzopyrene and trans fatty acids in peanut oil - Pan Gao; Yuling Zheng; Hui Liu; Wei Yang; Chuanrong Hu; Dongping He (Food Additives & Contaminants: Part A, 2022)

Early changes to the extracellular space in the hippocampus under simulated microgravity conditions - Yajuan Gao; Hongbin Han; Jichen Du; Qingyuan He; Yanxing Jia; Junhao Yan; Hui Dai; Bin Cui; Jing Yang; Xunbin Wei; Liu Yang; Rui Wang; et al. (Science China Life Sciences, 2022)

Precipitation recycling ratio and water vapor sources on the Tibetan Plateau - Kun Yang; Qiuhong Tang; Hui Lu (Science China Earth Sciences, 2022)

Assessment and improvement of Noah-MP for simulating water and heat exchange over alpine grassland in growing season - Shuang Sun; Donghai Zheng; Shaomin Liu; Ziwei Xu; Tongren Xu; Hui Zheng; Xiaofan Yang (Science China Earth Sciences, 2022)

Functional characterization of tyrosine decarboxylase genes that contribute to acteoside biosynthesis in Rehmannia glutinosa - Yan Hui Yang; Mu Rong Yang; Jian Yu Zhu; Ke Wei Dong; Yan Jie Yi; Rui Fang Li; Lei Zeng; Chang Fu Zhang (Planta, 2022)

Ectopic expression of GmRNF1a encoding a soybean E3 ubiquitin ligase affects Arabidopsis silique development and dehiscence - Zhongyi Yang; Yingjun Chi; Yanmei Cui; Zhen Wang; Dezhou Hu; Hui Yang; Javaid Akhter Bhat; Hui Wang; Guizhen Kan; Deyue Yu; Fang Huang (Planta, 2022)

Soybean Meal Extract Preserves Memory Ability by Increasing Presynaptic Function and Modulating Gut Microbiota in Rats - Kun-Chieh Yeh; Chi-Feng Hung; Hui-Ling Lee; Ting-Yang Hsieh; Su-Jane Wang (Molecular Neurobiology, 2022)

Ameliorative effect of scutellarin on acute alcohol brain injury in mice - Tianmeng Zhang; Kun Wang; Hui Fan; Qiankun Yang; Xiao Zhang; Feixue Liu; Xin Feng; Yi Chen; Daoyang Teng; Panpan Zhao; Jingquan Dong (Journal of Zhejiang University-SCIENCE B, 2022)

Genetic diversity analysis of forty-three insertion/deletion loci for forensic individual identification in Han Chinese from Beijing based on a novel panel - Congying Zhao; Jinlong Yang; Hui Xu; Shuyan Mei; Yating Fang; Qiong Lan; Yajun Deng; Bofeng Zhu (Journal of Zhejiang University-SCIENCE B, 2022)

Improving the Acid Resistance of Tannase TanBLp (AB379685) from Lactobacillus plantarum ATCC14917T by Site-Specific Mutagenesis - Hu Pan; Jingjing Zhan; Hui Yang; Chong Wang; Huhu Liu; Hui Zhou; Haiyan Zhou; Xiangyang Lu; Xiaojun Su; Yun Tian (Indian Journal of Microbiology, 2022)

Comprehensive Hydrodynamic Fitness of an Estuary Channel and the Effects of a Water Diversion Inflow - Wei He; Aili Jiang; Jian Zhang; Hui Xu; Yang Xiao; Sheng Chen; Xiaodong Yu (Estuaries and Coasts, 2022)

Preparation and evaluation of Pd-Sn modified Ru-Ir electrode for denitrification of high chlorine ammonia–nitrogen wastewater - Zhen-xing Yang; Jie Shang; Guang-xu Yan; Yu-xian Wang; Shao-hui Guo (Environmental Science and Pollution Research, 2022)

Migration and abiotic transformation of estrone (E1) and estrone-3-sulfate (E1-3S) during soil column transport - Banghao Du; Weiwei Yu; Lun Yang; Gongduan Fan; Shuo Yang; Hui Jiang; Shenglan Bi; Cheng Yu (Environmental Geochemistry and Health, 2022)

The impact of Typhoon Lekima (2019) on East China: a postevent survey in Wenzhou City and Taizhou City - Cong Zhou; Peiyan Chen; Shifang Yang; Feng Zheng; Hui Yu; Jie Tang; Yi Lu; Guoming Chen; Xiaoqing Lu; Xiping Zhang; Jing Sun (Frontiers of Earth Science, 2022)

Prevalence, complete genome, and metabolic potentials of a phylogenetically novel cyanobacterial symbiont in the coral‐killing sponge, Terpios hoshinota - Yu‐Hsiang Chen; Hsing‐Ju Chen; Cheng‐Yu Yang; Jia‐Ho Shiu; Daphne Z. Hoh; Pei‐Wen Chiang; Wenhua Savanna Chow; Chaolun Allen Chen; Tin‐Han Shih; Szu‐Hsien Lin; Chi‐Ming Yang; James Davis Reimer; et al. (Environmental Microbiology, 2022)
Summary Terpios hoshinota is an aggressive, space‐competing sponge that kills various stony corals. Outbreaks of this species have led to intense damage to coral reefs in many locations. Here, the first large‐scale 16S rRNA gene survey across three oceans revealed that bacteria related to the taxa Prochloron , Endozoicomonas , SAR116, Ruegeria , and unclassified Proteobacteria were prevalent in T . hoshinota . A Prochloron ‐related bacterium was the most dominant and prevalent cyanobacterium in T . hoshinota . The complete genome of this uncultivated cyanobacterium and pigment analysis demonstrated that it has phycobiliproteins and lacks chlorophyll b , which is inconsistent with the definition of Prochloron . Furthermore, the cyanobacterium was phylogenetically distinct from Prochloron , strongly suggesting that it should be a sister taxon to Prochloron . Therefore, we proposed this symbiotic cyanobacterium as a novel species under the new genus Candidatus Paraprochloron terpiosi. Comparative genomic analyses revealed that ‘Paraprochloron’ and Prochloron exhibit distinct genomic features and DNA replication machinery. We also characterized the metabolic potentials of ‘Paraprochloron terpiosi’ in carbon and nitrogen cycling and propose a model for interactions between it and T. hoshinota . This study builds a foundation for the study of the T . hoshinota microbiome and paves the way for better understanding of ecosystems involving this coral‐killing sponge.

Transition in tectonic regime from the Paleo-Asian Ocean to Paleo-Pacific Ocean: constraints from the Jurassic adakitic and I-type granites, and calc-alkaline diorites at the northern margin of the North China Craton - Yan Jing; Wen-Chun Ge; Yu Dong; Hao Yang; Zheng Ji; Jun-Hui Bi; Hong-Ying Zhou; De-He Xing (International Geology Review, 2022)

Toward Exploring Topographic Effects on Evolution and Propagation of Ocean Mesoscale Eddies Through Life Cycle Across Izu-Ogasawara Ridge in Northwestern Pacific Ocean - Rui Nian; Xue Geng; Zhengguang Zhang; Minghan Yuan; Zhen Fu; Hengfu Xu; Hua Yang; Qi Lai; Hui He; Chi Wei Su; Lina Zang; Qiang Yuan; et al. (Frontiers in Marine Science, 2022)
Ocean mesoscale eddies contribute significantly to water transport on a global scale, constituting the ubiquitous, irregular, discrete, nonlinear components. In this manuscript, we propose to explore whether and how the topographic effect of one meridional ridge, could exert considerable influences on the evolution and propagation of mesoscale eddies through their life cycle, directly from the perspectives of real observation statistics. We systematically investigate the known variability of mesoscale eddy trajectories, derived by multimission satellite altimetry from 1993 to 2018, of a life cycle more than 6 months, over the Izu-Ogasawara Ridge, and quantitatively examined the eddy-ridge interaction by observation statistics and wavelet coherence map, with respect to the intrinsic attributes, namely, the amplitude, the rotation speed, the radius. Due to the spatial-temporal diversity, a series of correlative steps have been particularly designed along time-frequency domain to trace back mesoscale eddy trajectories in a variety of origins, location, lifespan, polarity, either completely or partially passing over the ridge, and to facilitate the standardization in statistics across three phases of their life cycle, i.e., before, during and after the interaction with the ridge. It has been revealed in our experiment that three intrinsic attributes of mesoscale eddies within 25 years, all demonstrated noticeable correlation with the variation of topographic relief over the ridge. We observed that most of the cyclonic eddies obviously tended to begin to decay or even demise, while on the contrary, some of the anticyclonic eddies preferred to intensify slightly, or making no significant difference when encountering the upslope until climbing across the top, basically consistent with the expectation of potential vorticity (PV) conservation. The drifting velocity agreed with the tendency that the direction would be more probably modified toward equatorward or poleward by forcing to meridional component, with zonal component reduced at the beginning. The mesoscale eddies with the passage over the ridge exhibited the relatively high average horizontal scales, amplitude, rotation speed on the whole, compared to those with only partially passage. The developed scheme could integrate more evidences on how mesoscale eddies response to the topographic effects during their time-varying evolution and propagation process, and help provide opportunities to potentially identify and predict the underlying dynamic patterns and mechanisms that mesoscale eddies engage in ocean dynamics when proceeding toward meridional ridges on a global scale, with the promise of the end-to-end data-driven solution, such as deep learning architecture involved in the future.

VSIG4 Attenuates NLRP3 and Ameliorates Neuroinflammation via JAK2-STAT3-A20 Pathway after Intracerebral Hemorrhage in Mice - Na Ji; Lirong Wu; Hui Shi; Qianlu Li; Anyong Yu; Zhao Yang (Neurotoxicity Research, 2022)

Numerical Simulation of the Combined Slope Protection Effect of Living Stump and Bamboo Anchor - Yingbo Zhu; Hui Yang; Yong Liu; Xueliang Jiang; Riwen Deng; Li Huang; Peng Yin; Guojie Lai (Geotechnical and Geological Engineering, 2022)

Functional characterization of melanocortin-3 receptor in rainbow trout (Oncorhynchus mykiss) - Hui-Xia Yu; Yang Li; Wei-Jia Song; Hui Wang; Hao-Lin Mo; Qiao Liu; Xin-Miao Zhang; Ze-Bin Jiang; Li-Xin Wang (Fish Physiology and Biochemistry, 2022)

Utility of a pharmacogenetic-driven algorithm in guiding dual antiplatelet therapy for patients undergoing coronary drug-eluting stent implantation in China - Si-qi Lyu; Jun Zhu; Juan Wang; Shuang Wu; Han Zhang; Xing-hui Shao; Yan-min Yang (European Journal of Clinical Pharmacology, 2022)

The neonatal PROC gene rs1799809 polymorphism modifies the association between prenatal air pollutants exposure and PROC promoter methylation - Zhiyuan Li; Meng Yang; Leizhen Duan; Yongxiang Gong; Hongxia Xia; Francis-Kojo Afrim; Hui Huang; Xiaoxue Liu; Fangfang Yu; Yawei Zhang; Yue Ba; Guoyu Zhou (Environmental Science and Pollution Research, 2022)

The interception effect of heavy metals in different types of Chinese fir plantations - Aiai Yang; Jianguo Chen; Xiaoli Wang; Hui Guo; Dan Huang (Environmental Geochemistry and Health, 2022)

Metoprolol Protects Against Arginine Vasopressin-Induced Cellular Senescence in H9C2 Cardiomyocytes by Regulating the Sirt1/p53/p21 Axis - Qiang Li; Kang Huang; Tianyi Ma; Shijuan Lu; Shilin Tang; Miao Wu; Hui Yang; Jianghua Zhong (Cardiovascular Toxicology, 2022)
Cardiomyocyte senescence is involved in the pathological mechanism of cardiac diseases. Metoprolol is a β1 receptor blocker used for the treatment of hypertension. Recent studies show that Metoprolol can protect cardiomyocytes against ischemia injury. The present study aims to investigate the protective effects of Metoprolol against arginine vasopressin (AVP)-induced cellular senescence in cultured cardiomyocytes. The cell proliferation assay and cytotoxicity lactate dehydrogenase assay showed that the highest tolerated dosage of Metoprolol in H9C2 cardiomyocytes was optimized as 10 µM. The enzyme-linked immunosorbent assay showed that Metoprolol significantly ameliorated the elevated level of the DNA oxidation product 8-hydroxy-2 deoxyguanosine. Metoprolol also decreased the percentage of senescence-associated β-galactosidase positive cells and improved the telomerase activity under AVP exposure. Moreover, treatment with Metoprolol ameliorated the decreased intracellular nicotinamide phosphoribosyltransferase activity, nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phosphate (NAD + /NADPH) ratio, and Sirtuin1 activity in cardiomyocytes by AVP. Finally, Metoprolol was able to downregulate the AVP-induced expression of acetylated p53 and p21. Taken together, our data reveal that Metoprolol protected the cardiomyocytes from AVP-induced senescence.

Role of TGF-β1 in Fluoride-Treated Osteoblasts at Different Stages - Ningning Jiang; Wenshu Xu; Zhongyuan Zhang; Hui Jin; Yang Yang; Jingmin Zhang; Hui Xu (Biological Trace Element Research, 2022)

Selenium Attenuates S. aureus-Induced Inflammation by Regulation TLR2 Signaling Pathway and NLRP3 Inflammasome in RAW 264.7 Macrophages - Ming-Ji Wei; Zhen-Nan Wang; Yan Yang; Shu-Jiu Zhang; He Tang; Hui Li; Chong-Liang Bi (Biological Trace Element Research, 2022)

Identification and expression analysis of grape LRK10L-2 genes during grape fruit development - Jin-Ping Ma; Xue-Ren Yin; Tong-Lu Wei; Hai-Nan Liu; Mao-Song Pei; Sheng-Di Yang; Hui-Ying Jin; Guang-Qi He; Da-Long Guo (Plant Biotechnology Reports, 2022)

Responses and feedback of litter properties and soil mesofauna to herbaceous plants expansion into the alpine tundra on Changbai Mountain, China - Ying-jie Zhang; Ying-hua Jin; Jia-wei Xu; Hong-shi He; Yan Tao; Zhi-peng Yang; Jing Zhao; Yin-xia Diao; Chen-hui Sun; Mai-He Li (Journal of Mountain Science, 2022)

Multiple-Stage Mineralization in the Huayangchuan U−REE−Mo−Cu−Fe Ore Belt of the Qinling Orogen, Central China: Geological and Re−Os Geochronological Constraints - Hongjun Jiang; Chunsi Yang; Dequan Wang; Hui Zheng; Jie Li; Huayong Chen (Journal of Earth Science, 2022)
The Huayangchuan ore belt is located in the western segment of Xiaoqinling Orogen in the southern margin of the North China Craton (NCC), and hosts voluminous magmatism and significant U−REE−Mo−Cu−Fe polymetallic mineralization. However, geochronological framework of the various mineralization phases in this region is poorly understood. Here, we present new Re−Os isochron ages on magnetite from the Caotan Fe deposit (2 675 ± 410 Ma, MSWD = 0.55), and on pyrite from the Jialu REE deposit (2 127 ± 280 Ma, MSWD = 1.9) and Yuejiawa Cu deposit (418 ± 23 Ma, MSWD = 11.5), and Re−Os weighted average model age on pyrite from the Taoyuan Mo−U deposit (235 ± 14 Ma, MSWD = 0.17). These ages, combined with regional geology and mineralization ages from other deposits, suggest that mineralization in the Huayangchuan ore belt lasted from the Neoarchean to the Late Mesozoic. The mineralization corresponds to regional tectono-magmatic events, including the Neoar-chean alkali magmatism (REE mineralization), Paleoproterozoic plagioclase-amphibolite emplacement (Fe mineralization), Paleoproterozoic pegmatite magmatism (U mineralization), Paleozoic Shangdan oceanic slab subduction-related arc magmatism (Cu mineralization), Early Mesozoic Paleo-Tethys Ocean subduction-related arc magmatism (Mo−U mineralization), and Late Mesozoic Paleo-Pacific oceanic plate subduction direction change-related Mo(-Pb) mineralization. We proposed that the Huayang-chuan ore belt has undergone prolonged metallogenic evolution, and the magmatism and associated mineralization were controlled by regional geodynamic events.

miR-181b-5p Promotes the Progression of Cholangiocarcinoma by Targeting PARK2 via PTEN/PI3K/AKT Signaling Pathway - Zhe-Long Jiang; Fu-Xing Zhang; Hong-Liang Zhan; He-Jun Yang; Si-Yu Zhang; Zhao-Hui Liu; Yi Jiang; Li-Zhi Lv; Rui-Sheng Ke (Biochemical Genetics, 2022)

Rapid visual detection of porcine reproductive and respiratory syndrome virus via recombinase polymerase amplification combined with a lateral flow dipstick - Xiao-Xiao Tian; Tao Wang; Xing-Yang Cui; Xin-Yi Huang; Yue Sun; Da-Song Xia; Yong-Bo Yang; Xue-Hui Cai; Tong-Qing An (Archives of Virology, 2022)

Genetic divergence and local adaptation of Liriodendron driven by heterogeneous environments - Yufang Shen; Hui Xia; Zhonghua Tu; Yaxian Zong; Lichun Yang; Huogen Li (Molecular Ecology, 2022)
Ecological adaptive differentiation alters both the species diversity and intraspecific genetic diversity in forests, thus affecting the stability of forest ecosystems. Therefore, knowledge of the genetic underpinnings of the ecological adaptive differentiation of forest species is critical for effective species conservation. In this study, single‐nucleotide polymorphisms (SNPs) from population transcriptomes were used to investigate the spatial distribution of genetic variation in Liriodendron to assess whether environmental variables can explain genetic divergence. We examined the contributions of environmental variables to population divergence and explored the genetic underpinnings of local adaptation using a landscape genomic approach. Niche models and statistical analyses showed significant niche divergence between L . chinense and L . tulipifera , suggesting that ecological adaptation may play a crucial role in driving interspecific divergence. We detected a new fine‐scale genetic structure in L . chinense , and divergence of the six groups occurred during the late Pliocene to early Pleistocene. Redundancy analysis (RDA) revealed significant associations between genetic variation and multiple environmental variables. Environmental association analyses identified 67 environmental association loci (EALs; nonsynonymous SNPs) that underwent interspecific or intraspecific differentiation, 28 of which were associated with adaptive genes. These 28 candidate adaptive loci provide substantial evidence for local adaptation in Liriodendron . Our findings reveal ecological adaptive divergence pattern between Liriodendron species and provide novel insight into the role of heterogeneous environments in shaping genetic structure and driving local adaptation among populations, informing future L . chinense conservation efforts.

Climate warming promotes deterministic assembly of arbuscular mycorrhizal fungal communities - Xinyu Xu; Yunpeng Qiu; Kangcheng Zhang; Fei Yang; Mengfei Chen; Xi Luo; Xuebin Yan; Peng Wang; Yi Zhang; Huaihai Chen; Hui Guo; Lin Jiang; et al. (Global Change Biology, 2022)
Arbuscular mycorrhizal fungi (AMF) significantly contribute to plant resource acquisition and play important roles in mediating plant interactions and soil carbon (C) dynamics. However, it remains unclear how AMF communities respond to climate change. We assessed impacts of warming and precipitation alterations (30% increase or decrease) on soil AMF communities, and examined major ecological processes shaping the AMF community assemblage in a Tibetan alpine meadow. Our results showed that warming significantly increased root biomass, and available nitrogen (N) and phosphorus (P) in soil. While precipitation alterations increased AMF abundances, they did not significantly affect the composition or diversity of AMF communities. In contrast, warming altered the composition of AMF communities and reduced their Shannon–Wiener index and Pielou's evenness. In particular, warming shifted the AMF community composition in favor of Diversisporaceae over Glomeraceae, likely through its impact on soil N and P availability. In addition, AMF communities were phylogenetically random in the unwarmed control but clustered in warming plots, implying more deterministic community assembly under climate warming. Warming enhancement of root growth, N and P availability likely reduced plant C‐allocation to AMF, imposing stronger environmental filtering on AMF communities. We further proposed a conceptual framework that integrates biological and geochemical processes into a mechanistic understanding of warming and precipitation changes’ effects on AMF. Taken together, these results suggest that soil AMF communities may be more sensitive to warming than expected, highlighting the need to monitor their community structure and associated functional consequences on plant communities and soil C dynamics under the future warmer climate.

Tropical tall forests are more sensitive and vulnerable to drought than short forests - Liyang Liu; Xiuzhi Chen; Philippe Ciais; Wenping Yuan; Fabienne Maignan; Jin Wu; Shilong Piao; Ying‐Ping Wang; Jean‐Pierre Wigneron; Lei Fan; Pierre Gentine; Xueqin Yang; et al. (Global Change Biology, 2022)
Our limited understanding of the impacts of drought on tropical forests significantly impedes our ability in accurately predicting the impacts of climate change on this biome. Here, we investigated the impact of drought on the dynamics of forest canopies with different heights using time‐series records of remotely sensed Ku‐band vegetation optical depth (Ku‐VOD), a proxy of top‐canopy foliar mass and water content, and separated the signal of Ku‐VOD changes into drought‐induced reductions and subsequent non‐drought gains. Both drought‐induced reductions and non‐drought increases in Ku‐VOD varied significantly with canopy height. Taller tropical forests experienced greater relative Ku‐VOD reductions during drought and larger non‐drought increases than shorter forests, but the net effect of drought was more negative in the taller forests. Meta‐analysis of in situ hydraulic traits supports the hypothesis that taller tropical forests are more vulnerable to drought stress due to smaller xylem‐transport safety margins. Additionally, Ku‐VOD of taller forests showed larger reductions due to increased atmospheric dryness, as assessed by vapor pressure deficit, and showed larger gains in response to enhanced water supply than shorter forests. Including the height‐dependent variation of hydraulic transport in ecosystem models will improve the simulated response of tropical forests to drought.

Identifying Priority Conservation Areas of Largehead Hairtail (Trichiurus japonicus) Nursery Grounds in the East China Sea - Zunlei Liu; Yan Jin; Liping Yan; Yi Zhang; Hui Zhang; Chuyi Shen; Linlin Yang; Jiahua Cheng (Frontiers in Marine Science, 2022)
Identifying the spatio-temporal distribution hotspots of fishes and allocating priority conservation areas could facilitate the spatial planning and efficient management. As a flagship commercial fishery species, Largehead hairtail ( Trichiurus japonicus ) has been over-exploited since the early 2000s. Therefore, the spatio-temporal management of largehead hairtail nursery grounds could effective help its recovery. This study aims to predict juvenile largehead hairtail distribution patterns and identify priority conservation areas for nursery grounds. A two-stage hierarchical Bayesian spatio-temporal model was applied on independent scientific survey data (Catch per unit effort, CPUE) and geographic/physical variables (Depth, Distance to the coast, Sea bottom temperature, Dissolved oxygen concentration and Net primary production) to analyze the probability of occurrence and abundance distribution of juvenile largehead hairtail. We assessed the importance of each variable for explaining the occurrence and abundance. Using persistence index, we measured the robustness of hotspots and identified persistent hotspots for priority conservation areas. Selected models showed good predictive capacity on occurrence probability (AUC = 0.81) and abundance distribution ( r = 0.89) of juvenile largehead hairtail. Dissolved oxygen, net primary production, and sea bottom temperature significantly affected the probability of occurrence, while distance to the coast also affected the abundance distribution. Three stable nursery grounds were identified in Zhejiang inshore waters, the largest one was located on the east margin of the East China Sea hairtail national aquatic germplasm resources conservation zones (TCZ), suggesting that the core area of nursery grounds occurs outside the protected areas. Therefore, recognition of these sites and their associated geographic/oceanic attributes provides clear targets for optimizing largehead hairtail conservation efforts in the East China Sea. We suggested that the eastern and southern areas of TCZ should be included in conservation planning for an effective management within a network of marine protected areas.

Myrothecol A, a new alkylresorcinol with cytotoxicity from Myrothecium sp. - Zhen-Hua Li; Hui-Yuan Yang; Wen-Ting Zhu; Dong-Dong Jing; Shi-Neng Li; Peng-Ke Yan (Natural Product Research, 2022)

The evaluation of rock brittleness and its application: a review study - Yingjie Xia; Hui Zhou; Chuanqing Zhang; Shihai He; Yang Gao; Peng Wang (European Journal of Environmental and Civil Engineering, 2022)

Nanofiltration Membrane Fouling and Control Caused by Residual Aluminum in Feed Water - Hui-Bo Yu; Xian-Qiu Zhang; Xue Han; Zhen-Zhen Yang; Ya-Wen Zhou; Wen Ding; Ming-Xia Du (Water, Air, & Soil Pollution, 2022)

Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity - Junyan Han; Ning Zhang; Danying Chen; Yuhuan Gong; Guoli Li; Yaxian Kong; Lin Pu; Chen Chen; Jingyuan Liu; Qi Wang; Ju Zhang; Xuesen Zhao; et al. (Science China Life Sciences, 2022)

Identification of A-to-I RNA editing profiles and their clinical relevance in lung adenocarcinoma - Cheng Wang; Mingtao Huang; Congcong Chen; Yuancheng Li; Na Qin; Zijian Ma; Jingyi Fan; Linnan Gong; Hui Zeng; Liu Yang; Xianfeng Xu; Jun Zhou; et al. (Science China Life Sciences, 2022)

QTL mapping and candidate gene mining of flag leaf size traits in Japonica rice based on linkage mapping and genome-wide association study - Jiangxu Wang; Tao Wang; Qi Wang; Xiaodong Tang; Yang Ren; Haiyan Zheng; Kai Liu; Luomiao Yang; Hui Jiang; Yidan Li; Qi Liu; Detang Zou; et al. (Molecular Biology Reports, 2022)

A dynamically evolving war between autophagy and pathogenic microorganisms - Qianqian Zheng; Liangwei Duan; Yang Zhang; Jiaoyang Li; Shiyu Zhang; Hui Wang (Journal of Zhejiang University-SCIENCE B, 2022)

The difference in the intracellular Arg/Lys-rich and EHLVY motifs contributes to distinct subcellular distribution of HAI-1 versus HAI-2 - Nanxi Huang; Robert B. Barndt; Dajun D. Lu; Qiaochu Wang; Shih-Ming Huang; Jehng-Kang Wang; Ping-Ying Chang; Chao-Yang Chen; Je-Ming Hu; Hui-Chen Su; Michael D. Johnson; Chen-Yong Lin (Human Cell, 2022)

Ectomycorrhizal fungi enhance the tolerance of phytotoxicity and cadmium accumulation in oak (Quercus acutissima Carruth.) seedlings: modulation of growth properties and the antioxidant defense responses - Wen Sun; Baoshan Yang; Yidan Zhu; Hui Wang; Guanghua Qin; Hanqi Yang (Environmental Science and Pollution Research, 2022)

Water pollution characteristics of inflowing rivers under different land-use patterns in the Daye Lake basin: pollution mode and management suggestions - Weixiang Ren; Xiaodong Wu; Jiuyun Yang; Lu Luo; Song Liang; Hui Yang (Environmental Monitoring and Assessment, 2022)

Study on metal binding capacity of the freshwater crab Sinopotamon henanense’s recombinant copper specific binding metallothionein expressed in Escherichia coli - Lu Wang; Hui Zhen Yang; Wen Li Ma; Chien Min Chen; Lan Wang (Ecotoxicology, 2022)

Geochemical and Sr–Nd–Li isotopic constraints on the genesis of the Jiajika Li-rich pegmatites, eastern Tibetan Plateau: implications for Li mineralization - Hui Zhao; Bin Chen; Chao Huang; Chuang Bao; Qian Yang; Rui Cao (Contributions to Mineralogy and Petrology, 2022)

Asexual reproduction for overwintering of the submersed macrophyte Vallisneria spinulosa at different light intensities - Guixiang Yuan; Zhenzhi Yang; Lijun Sun; Hui Fu; Hui Peng; Erik Jeppesen (Aquatic Sciences, 2022)

Stage correlation of symbiotic bacterial community and function in the development of litchi bugs (Hemiptera: Tessaratomidae) - Zhi-Hui Liu; Zi-Wen Yang; Jing Zhang; Jiu-Yang Luo; Yu Men; Yan-hui Wang; Qiang Xie (Antonie van Leeuwenhoek, 2022)

Kangiella shandongensis sp. nov., a novel species isolated from saltern in Yantai, China - Li-Yang Peng; Rui Yin; Shu-Kun Gao; Hui-Ning Jiang; Xiao-Xiao Liu; Yu Ma; Yan-Xia Zhou (Antonie van Leeuwenhoek, 2022)

Progress and Principle of Drug Nanocrystals for Tumor Targeted Delivery - Meng Bai; Mingshi Yang; Junbo Gong; Hui Xu; Zhenping Wei (AAPS PharmSciTech, 2022)

Not out of the woods yet: Signatures of the prolonged negative genetic consequences of a population bottleneck in a rapidly re‐expanding wader, the black‐faced spoonbill Platalea minor - Shou‐Hsien Li; Yang Liu; Chia‐Fen Yeh; Yuchen Fu; Carol K. L. Yeung; Chun‐Cheng Lee; Chi‐Cheng Chiu; Tung Hui Kuo; Fang‐Tse Chan; Yu‐Chia Chen; Wen‐Ya Ko; Cheng‐Te Yao (Molecular Ecology, 2022)
The long‐term persistence of a population which has suffered a bottleneck partly depends on how historical demographic dynamics impacted its genetic diversity and the accumulation of deleterious mutations. Here we provide genomic evidence for the genetic effect of a recent population bottleneck in the endangered black‐faced spoonbill ( Platalea minor ) after its rapid population recovery. Our data suggest that the bird's effective population size, N e , had been relatively stable (7500–9000) since 22,000 years ago; however, a recent brief yet severe bottleneck ( N e = 20) which we here estimated to occur around the 1940s wiped out >99% of its historical N e in roughly three generations. Despite a >15‐fold population recovery since 1988, we found that black‐faced spoonbill population has higher levels of inbreeding (7.4 times more runs of homozygosity) than its sister species, the royal spoonbill ( P. regia ), which is not thought to have undergone a marked population contraction. Although the two spoonbills have similar levels of genome‐wide genetic diversity, our results suggest that selection on more genes was relaxed in the black‐faced spoonbill; moreover individual black‐faced spoonbills carry more putatively deleterious mutations (Grantham's score > 50), and may therefore express more deleterious phenotypic effects than royal spoonbills. Here we demonstrate the value of using genomic indices to monitor levels of genetic erosion, inbreeding and mutation load in species with conservation concerns. To mitigate the prolonged negative genetic effect of a population bottleneck, we recommend that all possible measures should be employed to maintain population growth of a threatened species.

The Identification and Prediction of Mesoscale Eddy Variation via Memory in Memory With Scheduled Sampling for Sea Level Anomaly - Rui Nian; Yu Cai; Zhengguang Zhang; Hui He; Jingyu Wu; Qiang Yuan; Xue Geng; Yuqi Qian; Hua Yang; Bo He (Frontiers in Marine Science, 2021)
Ocean mesoscale eddies are ubiquitous in world ocean and account for 90% oceanic kinetic energy, which dominate the upper ocean flow field. Accurately predicting the variation of ocean mesoscale eddies is the key to understand the oceanic flow field and circulation system. In this article, we propose to make an initial attempt to explore spatio-temporal predictability of mesoscale eddies, employing deep learning architecture, which primarily establishes Memory In Memory (MIM) for sea level anomaly (SLA) prediction, combined with the existing mesoscale eddy detection. Oriented to the western Pacific ocean (125°−137.5°E and 15°−27.5°N), we quantitatively investigate the historic daily SLA variability at a 0.25° spatial resolution from 2000 to 2018, derived by satellite altimetry. We develop the enhanced MIM prediction strategies, equipped with Gated Recurrent Unit (GRU) and spatial attention module, in a scheduled sampling manner, which overcomes the gradient vanishing and complements to strengthen spatio-temporal features for long-term dependencies. At the early stage, the real value SLA input guides the model training process for initialization, while the scheduled sampling intentionally feeds the newly predicted value, to resolve the distribution inconsistency of inference. It has been demonstrated in our experiment results that our proposed prediction scheme outperformed the state-of-art approaches for SLA time series, with MAPE, RMSE of the 14-day prediction duration, respectively, 5.1%, 0.023 m on average, even up to 4.6%, 0.018 m for the effective sub-regions, compared to 19.8%, 0.086 m in ConvLSTM and 8.3%, 0.040 m in original MIM, which greatly facilitated the mesoscale eddy prediction. This proposed scheme will be beneficial to understand of the underlying dynamical mechanism behind the predictability of mesoscale eddies in the future, and help the deployment of ARGO, glider, AUV and other observational platforms.

Investigation of factors influencing the release of chloropropanols (3-MCPD and 1,3-DCP) from food contact paper - Huai-ning Zhong; Ying Zeng; Dao-yuan Yang; Ze-chun Wu; Dan Li; Hai-xia Sui; Jie Gao; Yan-fen Chen; Ce-Hui Mo (Food Additives & Contaminants: Part A, 2021)

Ifenprodil Improves Long-Term Neurologic Deficits Through Antagonizing Glutamate-Induced Excitotoxicity After Experimental Subarachnoid Hemorrhage - Jing-yi Sun; Shi-jun Zhao; Hong-bin Wang; Ya-jun Hou; Qiong-jie Mi; Ming-feng Yang; Hui Yuan; Qing-bin Ni; Bao-liang Sun; Zong-yong Zhang (Translational Stroke Research, 2021)

The xyloglucan galactosylation modulates the cell wall stability of pollen tube - Qiqi Wei; Ying Yang; Hui Li; Zhiwen Liu; Rong Fu; Hanqian Feng; Chao Li (Planta, 2021)

Identification of key gene networks controlling vernalization development characteristics of Isatis indigotica by full-length transcriptomes and gene expression profiles - Pan Wang; Dong Liu; Fu-Hong Yang; Hui Ge; Xin Zhao; Hong-Gang Chen; Tao Du (Physiology and Molecular Biology of Plants, 2021)
Isatis indigotica Fort . , as a common Chinese medicinal raw material, will lose its medicinal value if it blooms early, so it is highly valuable to clarify the induction mechanism of the vernalization of I. indigotica at low temperature. In this study, the concentrations of soluble sugar, proline, glutathione and zeatin in two germplasms of I. indigotica with different degrees of low temperature tolerance (Y1 and Y2) were determined at 10 days, 20 days and 30 days of low-temperature treatment, and the full-length transcriptome of 24 samples was sequenced by Nanopore sequencing with Oxford Nanopore Technologies (ONT). After that, the data of transcripts involved in the vernalization of I. indigotica at low temperature were obtained, and these transcripts were identified using weighted gene co-expression network analysis (WGCNA). The results revealed the massive accumulation of soluble sugar and proline in Y1 and Y2 after low temperature induction. A total of 18,385 new transcripts, 6168 transcription factors and 470 lncRNAs were obtained. Differential expression analysis showed that gibberellin, flavonoids, fatty acids and some processes related to low temperature response were significantly enriched. Eight key transcripts were identified by WGCNA, among which ONT.14640.1, ONT.9119.1, ONT.13080.2 and ONT.16007.1 encodes a flavonoid transporter, 9-cis-epoxycarotenoid dioxygenase 3 (NCED3), growth factor gene and L-aspartate oxidase in plants, respectively . It indicated that secondary metabolites such as hormones and flavonoids play an important role in the vernalization of I. indigotica . qRT-PCR proved the reliability of transcriptome results. These results provide important insights on the low-temperature vernalization of I. indigotica , and provide a research basis for analyzing the vernalization mechanism of I. indigotica .

Opicapone Protects Against Hyperhomocysteinemia-Induced Increase in Blood–Brain Barrier Permeability - Jian Wang; Bo Zheng; Shu Yang; Hui Zheng; Jianhong Wang (Neurotoxicity Research, 2021)

Exploring Chinese College Students’ HPV Awareness, Knowledge, Attitudes, and Intent of HPV Vaccination: a Qualitative Study - Angela Chia-Chen Chen; Calli Astroth; Elizabeth Reifsnider; Hui Yang; Wenlan Mao; Hong Chen (Journal of Cancer Education, 2021)

Investigations of solid culture–induced acquisition of desiccation tolerance in liquid suspension culture of Nostoc flagelliforme - Xiao-Long Yuan; Xiang Gao; Wen Liu; Yang She; Tao Zheng; Hui-Dan Xue (Journal of Applied Phycology, 2021)

Cu(II) and Cd(II) removal from aqueous solution with LDH@GO-NH2 and LDH@GO-SH: kinetics and probable mechanism - Wei Liao; Di Bao; Hui-qiang Li; Ping Yang (Environmental Science and Pollution Research, 2021)

Detoxification difference of cadmium between the application of selenate and selenite in native cadmium-contaminated soil - Mingxing Qi; Yang Liu; Yanan Li; Min Wang; Nana Liu; Pornpimol Kleawsampanjai; Fei Zhou; Hui Zhai; Mengke Wang; Quang Toan Dinh; Rui Ren; Dongli Liang (Environmental Science and Pollution Research, 2021)

Low-carbon supply chain optimization considering warranty period and carbon emission reduction level under cap-and-trade regulation - Shaojian Qu; Hui Yang; Ying Ji (Environment, Development and Sustainability, 2021)

Correction to: Ocean acidification alters the thermal performance curves of brooded larvae from the reef coral Pocillopora damicornis - Lei Jiang; You-Fang Sun; Yu-Yang Zhang; Yuan Tian; Xin-Ming Lei; Guo-Wei Zhou; Tao Yuan; Xiang-Cheng Yuan; Sheng Liu; Hui Huang (Coral Reefs, 2021)

Heterologous expression of Solanum tuberosum NAC1 gene confers enhanced tolerance to salt stress in transgenic Nicotiana benthamiana - Lu Yue; Yong Zhuang; Yuanyang Gu; Hui Li; Shengbin Tu; Xiaocheng Yang; Weizao Huang (Journal of Plant Biology, 2021)

Mechanism of pore pressure variation in multiple coal reservoirs, western Guizhou region, South China - Wei Ju; Zhaobiao Yang; Yulin Shen; Hui Yang; Geoff Wang; Xiaoli Zhang; Shengyu Wang (Frontiers of Earth Science, 2021)

Application of lipidomics strategy to explore aging-related biomarkers and potential anti-aging mechanisms of ginseng - Shenshen Yang; Yaqian Dong; Yuechen Liu; Xingxu Yan; Guijiang Sun; Guoxiang Jia; Xiaokai Li; Hui Liu; Haihua Su; Yubo Li (Biogerontology, 2021)

The first third-generation HIV-1 circulating recombinant form (CRF114_0155) identified in central China - Yang Li; Yan Zhang; Hongye Wang; Long Liu; Hui Chen; Shuanhu Zhang; Wenying Wu; Rongge Yang (Archives of Virology, 2021)

Effects of replacing fishmeal with soybean protein concentrate (SPC) on growth, blood biochemical indexes, non-specific immune enzyme activity, and nutrient apparent digestibility for juvenile Litopenaeus vannamei - Zhan-Hao Zhu; Qi-hui Yang; Bei-ping Tan; Xiao-Qiu Zhou; Xiao-hui Dong; Shu-yan Chi; Hong-yu Liu; Shuang Zhang (Aquaculture International, 2021)

Correction to: AGGF1 protects from myocardial ischemia/reperfusion injury by regulating myocardial apoptosis and angiogenesis - Yu Liu; Hui Yang; Lina Song; Nan Li; Qiu-Yue Han; Cui Tian; Erhe Gao; Jie Du; Yun-Long Xia; Hui-Hua Li (Apoptosis, 2021)

Gephyromycinifex aptenodytis gen. nov., sp. nov., isolated from gut of Antarctic emperor penguin Aptenodytes forsteri - Wen-Zhuo Zhu; Ya-Ming Ge; Hui-Min Gao; Jun Dai; Xiao-Ling Zhang; Qiao Yang (Antonie van Leeuwenhoek, 2021)

Radial velocity of ocean surface current estimated from SAR Doppler frequency measurements—a case study of Kuroshio in the East China Sea - Lihua Wang; Benwei Shi; Yunxuan Zhou; Hui Sheng; Yanghua Gao; Li Fan; Ziheng Yang (Acta Oceanologica Sinica, 2021)

Ecological studies of colonized invertebrate communities on cultivated seaweeds in a typical mariculture zone, China - Qing Wang; Hui Ren; Yufeng Yang (Marine Ecology, 2021)
The invertebrate communities on floating cultivated seaweeds were studied by both field surveys and experiments in order to analyze community structure in a typical mariculture zone, Nanao, South China. Samples of invertebrates were collected from the water and the thalli of the seaweeds, Gracilaria lemaneiformis and G. chouae . The results showed that both species were rapidly colonized by invertebrates after being introduced into the mariculture region. The communities on the seaweeds were significantly different from those in the ambient waters. Invertebrate abundance was much higher in the seaweed than in the water. The high proportion of larvae indicates that these species are using the seaweed thalli as a platform for reproduction. Therefore, large‐scale seaweed cultivation is beneficial for colonization of invertebrates and shelters higher numbers of copepod larvae than in the sea. This drives ecological changes in the invertebrate communities in coastal ecosystems and facilitates interactions with other communities and higher trophic levels in the cultivated seaweed food web. We propose a conceptual model that summarizes the results from this study and guides future studies on the relationships between seaweed and the invertebrate community.

Theoretical and Numerical Analysis of Blasting Pressure of Cylindrical Shells under Internal Explosive Loading - Zhan-Feng Chen; Hui-Jie Wang; Zhiqian Sang; Wen Wang; He Yang; Wei-Ming Meng; Yu-Xing Li (Journal of Marine Science and Engineering, 2021)
Cylindrical shells are principal structural elements that are used for many purposes, such as offshore, sub-marine, and airborne structures. The nonlinear mechanics model of internal blast loading was established to predict the dynamic blast pressure of cylindrical shells. However, due to the complexity of the nonlinear mechanical model, the solution process is time-consuming. In this study, the nonlinear mechanics model of internal blast loading is linearized, and the dynamic blast pressure of cylindrical shells is solved. First, a mechanical model of cylindrical shells subjected to internal blast loading is proposed. To simplify the calculation, the internal blast loading is reduced to linearly uniform variations. Second, according to the stress function method, the dynamic blast pressure equation of cylindrical shells subjected to blast loading is derived. Third, the calculated results are compared with those of the finite element method (FEM) under different durations of dynamic pressure pulse. Finally, to reduce the errors, the dynamic blast pressure equation is further optimized. The results demonstrate that the optimized equation is in good agreement with the FEM, and is feasible to linearize the internal blast loading of cylindrical shells.

Dammarane-type saponins from Gynostemma pentaphyllum and their cytotoxicities - Wei-Ye Cui; Yulian Jin; Hui Liu; Ma-Li Zu; Xin-Fang Zhai; Ce Yang; Yu-Long Gu; Yong Cheng; Xiang-Lan Piao (Natural Product Research, 2021)

Cytotoxic triterpenoid glycosides from leaves of Cyclocarya paliurus - Hui-Hui Sun; Wen-Yan Lv; Jie Tan; Yu-Cheng Tang; Hui Zhu; Jian-Bo Qu; Jing Li; Jian-Ping Wu; Xi-Wen Chang; Zhi-Chun Yang; Wen-Xuan Wang; Zu-Hui Chen; et al. (Natural Product Research, 2021)

Abnormal meiosis in fertile and sterile triploid cyprinid fish - Chun Zhang; Qi Li; La Zhu; Wangchao He; Conghui Yang; Hui Zhang; Yu Sun; Luojing Zhou; Yuandong Sun; Shurun Zhu; Chang Wu; Min Tao; et al. (Science China Life Sciences, 2021)

Correction to: Foliation Effects on Mechanical and Failure Characteristics of Slate in 3D Space Under Brazilian Test Conditions - Changdong Ding; Yang Zhang; Dawei Hu; Hui Zhou; Jianfu Shao (Rock Mechanics and Rock Engineering, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

Long non-coding RNA HOXA-AS3 facilitates the malignancy in colorectal cancer by miR-4319/SPNS2 axis - Yang Jiang; Xiao-yu Yu; Hui-xin Sun; Xin-yue Gu; Jing-shu Geng (Journal of Physiology and Biochemistry, 2021)

New interpretation of the rupture process of the 2016 Taiwan Meinong Mw 6.4 earthquake based on the InSAR, 1-Hz GPS and strong motion data - Ying-Hui Yang; Qiang Chen; Xin Diao; Jingjing Zhao; Lang Xu; Jyr-Ching Hu (Journal of Geodesy, 2021)

Emerging roles of circUBAP2 targeting miR-370-3p in proliferation, apoptosis, and invasion of papillary thyroid cancer cells - Hui Xiong; Jinsong Yu; Guangwei Jia; Yang Su; Jianliang Zhang; Qiu Xu; Xiaoxiong Sun (Human Cell, 2021)