Updates to the RIFM Criteria Document for fragrance ingredient evaluation - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 2-propanol, 1,1′,1′,1'-(1,2-ethanediyldinitrilo)tetrakis-, CAS Registry Number 102-60-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, octyl crotonate, CAS Registry Number 22874-79-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, propenylguaethol, CAS Registry Number 94-86-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, ethyl 3-hydroxybutyrate, CAS Registry Number 5405-41-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 3-(p-tert-butylphenyl)-2-methylpropanol, CAS Registry Number 56107-04-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, ethyl 3-hydroxyhexanoate, CAS Registry Number 2305-25-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, linoleic acid, CAS Registry Number 60-33-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, β-naphthyl isobutyl ether, CAS Registry Number 2173-57-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 1,5-dimethylhexyl acetate, CAS Registry Number 67952-57-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 3-(4-methyl-3-pentenyl)-3-cyclohexene-1-carbonitrile, CAS Registry Number 68084-04-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, cyclohexaneethyl acetate, CAS Registry Number 21722-83-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 3,5,5-trimethylcyclohexanol, CAS Registry Number 116-02-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 5-methyl-2-phenyl-2-hexenal, CAS Registry Number 21834-92-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 4-heptanol, 2,6-dimethyl-,acetate, CAS Registry Number 10250-45-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, phenylacetaldehyde glyceryl acetal, CAS Registry Number 29895-73-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, cyclohexanemethanol, 2,4-dimethyl-, CAS Registry Number 68480-15-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, cis-4-(isopropyl)cyclohexanemethanol, CAS registry number 13828-37-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, cyclohexanone, 2-ethyl-4,4-dimethyl-, CAS registry number 55739-89-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, squalene, CAS Registry Number 111-02-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, β-guaiene, CAS Registry Number 88-84-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 3-hexene, 1,1′,''-[ethylidynestris(oxy)]tris-, (3Z, 3′Z,3"Z)-, CAS registry number 215305-10-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, methyl 3-hydroxyhexanoate, CAS Registry Number 21188-58-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 4-methyl-2-phenyl-2-pentenal, CAS Registry Number 26643-91-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 2-phenyl-2-butenal, CAS Registry Number 4411-89-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, dodecyldimethylamine oxide, CAS Registry Number 1643-20-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, tricosane, CAS Registry Number 638-67-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, methyl 2-nonenoate, CAS registry number 111-79-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 4-(isopropyl)-β-methylcyclohexanethanol, CAS Registry Number 67634-03-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, undecanol, CAS Registry Number 30207-98-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, methyl cis-5-octenoate, CAS Registry Number 41654-15-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, methyl 3-nonenoate, CAS Registry Number 13481-87-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 4-methyl-3-penten-2-one, CAS Registry Number 141-79-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, methyl 3-hexenoate, CAS Registry Number 2396-78-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)ethanone, CAS Registry Number 54464-57-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, docosane, CAS Registry Number 629-97-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, methyl jasmonate, CAS Registry Number 1211-29-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 2-isobutyl-4-methyltetrahydro-2H-pyran-4-ol, CAS Registry Number 63500-71-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, dimyrcene, CAS Registry Number 532-87-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, methyl myristate, CAS Registry Number 124-10-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, cyclohexane, 1-ethenyl-1-methyl-2,4-bis(1-methylethenyl)-, (1R,2R,4S)-rel-, CAS Registry Number 33880-83-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, ethyl myristate, CAS Registry Number 124-06-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 2-methylpentyl 2-methylvalerate, CAS Registry Number 90397-38-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, pyrazine, methyl (methylthio)-, CAS Registry Number 67952-65-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 2-propenoic acid, 2-[1-(3,3-dimethylcyclohexyl)ethoxy]-2-methylpropyl ester, CAS Registry Number 820975-49-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, hexadecyl palmitate, CAS Registry Number 540-10-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, cyclohexane, 1-ethenyl-1-methyl-2-(1-methylethenyl)-4-(1-methylethyl)-, didehydro derivative, CAS Registry Number 68845-33-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, acetyl cedrene, CAS Registry Number 32388-55-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, butyl sulfide, CAS Registry Number 544-40-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, heneicosane, CAS Registry Number 629-94-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, ethyl palmitate, CAS Registry Number 628-97-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, sclareol, CAS registry number 515-03-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, ethyl octadecanoate, CAS Registry Number 111-61-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, cyclohexyl methyl pentanone, CAS Registry Number 4927-39-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, heptadecane, CAS Registry Number 629-78-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, hexadecane, CAS Registry Number 544-76-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, oleic acid, CAS Registry Number 112-80-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, pentadecane, CAS Registry Number 629-62-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, tetradecane, CAS Registry Number 629-59-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, nonadecane, CAS Registry Number 629-92-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, octadecane, CAS Registry Number 593-45-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, eicosane, CAS Registry Number 112-95-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessments, ethyl ricinoleate, CAS Registry Number 55066-53-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 4-methyl-8-methylenetricyclo[3.3.1.(3,7)]decan-2-yl acetate, CAS Registry Number 122760-85-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, phytyl acetate, CAS Registry Number 10236-16-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, [2,2-bis[(3,7-dimethyl-2,6-octadienyl)oxy]ethyl]benzene, CAS Registry Number 67634-02-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 2,3,5,6-tetramethylpyrazine, CAS Registry Number 1124-11-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, cedryl methyl ether, CAS Registry Number 67874-81-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, methyl 2-(formylamino)benzoate, CAS Registry Number 41270-80-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)-, CAS Registry Number 6790-58-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, laurel leaf oil, CAS Registry Number 8007-48-5, RIFM ID 476-E2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, (Z)-2-penten-1-ol, CAS Registry Number 1576-95-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 6-methyl-3,5-heptadien-2-one, CAS Registry Number 1604-28-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, isopropylphenylbutanal, CAS Registry Number 125109-85-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, methyl cinnamate, CAS Registry Number 103-26-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, lovage leaf oil, CAS Registry Number 8016-31-7, RIFM ID 813-E2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, β,β,3-trimethyl benzenepropanol, CAS Registry Number 103694-68-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, dihydro-β-ionone, CAS registry number 17283-81-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 3-hexanone, CAS Registry Number 589-38-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, ethyl methylphenylglycidate, CAS Registry Number 77-83-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, dihydro-α-ionone, CAS Registry Number 31499-72-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, hinoki root oil, CAS Registry Number 91745-97-0, RIFM ID 5487-A2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, isobornyl methyl ether, CAS Registry Number 5331-32-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, ethyl safranate, CAS registry number 35044-57-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, Bucchu oil, betulina, CAS Registry Number 68650-46-4, RIFM ID 73-E2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, ethyl pyruvate, CAS registry number 617-35-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, thyme oil, red, CAS Registry Number 8007-46-3, RIFM ID 471.E2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 2-methyl-3-tolylpropionaldehyde, CAS Registry Number 41496-43-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, dihydrocarvyl acetate, CAS Registry Number 20777-49-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 3,7-dimethyl-2,6-nonadien-1-al, CAS Registry Number 41448-29-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, isopulegyl acetate, CAS Registry number 57576-09-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, anisyl alcohol, CAS Registry Number 105-13-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, bicyclo[3.1.0]hexan-3-one, 4-methyl-1-(1-methylethyl)-, CAS Registry Number 1125-12-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 6-isopropyl-2(1H)-octahydronaphthalenone, CAS Registry Number 34131-98-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, ethyl 3-phenylglycidate, CAS Registry Number 121-39-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, citral, CAS Registry Number 5392-40-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 1,6-octadien-3-ol, 3,7-dimethyl-, acid-isomerized, CAS Registry Number 73018-51-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, 1,1-dimethoxycyclododecane, CAS Registry Number 950-33-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 2-ethyl-5-methoxybicyclo[2.2.1]heptane, CAS registry number 122795-41-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM natural complex substance (NCS) fragrance ingredient safety assessment, styrax absolute, CAS registry Number 8024-01-9, RIFM ID 6877.K2.1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, α,α-dimethyl-p-ethylphenylpropanal, CAS Registry Number 67634-15-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

RIFM fragrance ingredient safety assessment, α-hexylcinnamaldehyde, CAS Registry Number 101-86-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, γ-octalactone, CAS Registry number 104-50-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 4-methoxybenzoic acid, CAS Registry Number 100-09-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, 3-methyl-2-butenyl acetate, CAS Registry Number 1191-16-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, γ-hexalactone, CAS Registry Number 695-06-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, myristic acid, CAS Registry Number 544-63-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, isobutyric acid, CAS Registry Number 79-31-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, γ-decalactone, CAS Registry Number 706-14-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, γ-undecalactone, CAS Registry Number 104-67-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, isovaleric acid, CAS Registry Number 503-74-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

Update to RIFM fragrance ingredient safety assessment, γ-nonalactone, CAS Registry Number 104-61-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2026)

2nd update to RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1,6-nonadien-3-ol, CAS Registry Number 10339-55-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

2nd update to RIFM fragrance ingredient safety assessment, linalool, CAS Registry number 78-70-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2H-indeno[4,5b] furan, decahydro-2,2,6,6,7,8,8-heptamethyl, CAS Registry Number 476332-65-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, γ-dodecalactone, CAS Registry Number 2305-05-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, palmitic acid, CAS Registry number 57-10-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2,6,8-trimethylnonan-4-one, CAS Registry Number 123-18-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-methylbutyric acid, CAS Registry number 116-53-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 4,8-dimethyl-4,9-decadienal, CAS Registry number 71077-31-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, cedrene, CAS Registry Number 11028-42-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 5-methyl-3-heptanone, CAS Registry Number 541-85-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM natural complex substance (NCS) fragrance ingredient safety assessment, iris pallida oil, CAS registry number 8002-73-1, RIFM ID 265.A2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 8H-indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl mixture of isomers, CAS Registry Number 338735-71-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-nonanone, CAS Registry Number 821-55-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-undecanone, CAS Registry Number 112-12-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 3-octanone, CAS registry number 106-68-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-decanone, CAS Registry Number 693-54-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-heptanone, CAS Registry Number 110-43-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, γ-heptalactone, CAS Registry Number CAS # 105-21-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, γ-valerolactone, CAS Registry Number 108-29-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, lauric acid, CAS Registry Number 143-07-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-octanone, CAS Registry Number 111-13-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, benzoin infusion, Sumatra, CAS Registry Number 9000-05-9, RIFM ID 104-K2.31 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 4-heptanone, CAS Registry Number 123-19-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 3-heptanone, CAS Registry Number 106-35-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, myrtenol, CAS Registry Number 515-00-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 3-phenylpropionic acid, CAS registry number 501-52-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, hexyl phenylacetate, CAS Registry Number 5421-17-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, methyl cyclohexadiene (mixture of isomers), CAS Registry Number 30640-46-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, decanoic acid, CAS Registry Number 334-48-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 5-methyl-5-propyl-2-(1-methylbutyl)-1,3-dioxan, CAS Registry Number 80480-24-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, octanoic acid, CAS Registry Number 124-07-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, p-isopropylacetophenone, CAS Registry Number 645-13-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, nonanoic acid, CAS Registry Number 112-05-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 4H-4a,9-methanoazuleno[5,6-d]-1,3-dioxole, octahydro-2,2,5,8,8,9a-hexamethyl-, (4aR,5R,7aS,9R)-, CAS Registry Number 211299-54-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, spiro[5.5]undec-8-en-1-one, 2,2,7,9-tetramethyl-, CAS Registry Number 502847-01-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, p-tolyl 3-methylcrotonate, CAS Registry Number 24700-20-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, hexanoic acid, CAS Registry Number 142-62-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-methyl-4-phenyl-1,3-dioxolane, CAS Registry Number 33941-99-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-hydroxyacetophenone, CAS Registry Number CAS # 118-93-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 4-isopropyl-2-methoxy-1-methylbenzene, CAS Registry Number 6379-73-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 1-ethynylcyclohexyl acetate, CAS Registry Number 5240-32-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 4,4a,5,9b-tetrahydroindeno[1,2-d]-1,3-dioxine, CAS Registry Number 18096-62-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 3-phenyl-1-propanol, CAS Registry Number 122-97-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, benzaldehyde, CAS Registry Number 100-52-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, benzeneacetonitrile, a-butylidene-, (Z), CAS Registry Number 130786-09-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, geraniol, CAS registry number 106-24-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-phenoxyethanol, CAS Registry number 122-99-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, cinnamyl alcohol, CAS Registry Number 104-54-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, benzyl alcohol, CAS Registry Number 100-51-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, benzoic acid, 2-[[3-(4-methoxyphenyl)-2-methylpropylidene]amino]-, methyl ester, CAS registry number 111753-62-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

2nd update to RIFM fragrance ingredient safety assessment, 4-carvomenthenol, CAS Registry Number 562-74-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 2-tert-butylcyclohexyl acetate, CAS registry number 88-41-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 3-tert-butylcyclohexyl acetate, CAS Registry Number 31846-06-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 4-tert-butylcyclohexyl acetate, CAS Registry Number 32210-23-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

P32-13 Outside the validated range: Performing a Weight of Evidence (WoE) assessment of the skin sensitization potential for fragrance chemicals positive at high concentrations only in the Local Lymph Node Assay (LLNA) - M. Lavelle; A. Natsch; I. Lee; I. Schember; V. Rocha; J. Muldoon; H. Moustakas; A.M. Api (Toxicology Letters, 2025)

RIFM fragrance ingredient safety assessment, phenyl salicylate, CAS Registry Number 118-55-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, fenchone, CAS Registry Number 1195-79-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, phenethyl acetate, CAS registry number 103-45-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, hydroxycitronellal diethyl acetal, CAS Registry Number 7779-94-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, amylcyclohexyl acetate (mixed isomers), CAS Registry Number 67874-72-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, octanal dimethyl acetal, CAS Registry Number 10022-28-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, linalyl hexanoate, CAS Registry Number 7779-23-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-methylundecanal dimethyl acetal, CAS Registry Number 68141-17-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, hydroxycitronellal dimethyl acetal, CAS Registry number 141-92-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 2-isobutylquinoline, CAS registry number 93-19-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 2-methyl quinoline, CAS registry number 91-63-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 1,1-diethoxyisooctane, CAS Registry Number 69178-43-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, nonane, 1,1-diethoxy-, CAS Registry Number 54815-13-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 1,1-diethoxy-3,5,5-trimethylhexane, CAS registry number 86198-35-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 2-(methylpropyl)quinoline, CAS registry number 1333-58-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, decanal dimethyl acetal, CAS Registry Number 7779-41-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 4-isopropylphenol, CAS Registry Number 99-89-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 3-buten-2-one, 4-(2,2,3-trimethyl-6-methylenecyclohexyl)-, CAS registry number 79-68-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, heptanal dimethyl acetal, CAS registry number 10032-05-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 1,1-diethoxyhexane, CAS registry number 3658-93-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 2-acetyl-5-methylfuran, CAS Registry Number 1193-79-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isophytol, CAS Registry Number 505-32-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 2-furyl methyl ketone, CAS Registry Number 1192-62-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, savory winter oil, CAS Registry Number 90106-57-3, RIFM ID 1181-E2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM natural complex substance (NCS) fragrance ingredient safety assessment, ho wood oil, CAS Registry Number 8022-91-1, RIFM ID 217-D2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, dimethylcyclohex-3-ene-1-carbaldehyde (isomer unspecified), CAS Registry Number 27939-60-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol, CAS Registry Number 515-69-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, maltol, CAS registry number 118-71-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 3-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexan-1-ol, CAS registry number 3407-42-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, benzyl valerate, CAS Registry Number 10361-39-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isocyclocitral, CAS Registry Number 1335-66-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, ho leaf oil, CAS Registry Number 8022-91-1, RIFM ID 217-E2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM natural complex substance (NCS) fragrance ingredient safety assessment, ho bark oil, CAS registry number 8022-91-1, RIFM ID 217-C2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 1,1-diethoxyheptane, CAS Registry Number 688-82-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 1-octanol, CAS registry number 111-87-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 4,4a,6,7,8,8a-hexahydro-1,4-methanonaphthalen-5(1H)-one, CAS Registry Number 51519-65-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, amyl hexanoate, CAS registry number 540-07-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, undecanal, CAS Registry Number 112-44-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, N-benzoylanthranilic acid, CAS Registry Number 579-93-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, undecyl alcohol, CAS Registry Number 112-42-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 1-tridecanol, CAS Registry Number 112-70-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, lauryl alcohol, CAS Registry Number 112-53-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, hexyl alcohol, CAS Registry Number 111-27-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, ethyl maltol, CAS Registry Number 4940-11-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, butyrophenone, CAS Registry Number 495-40-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, p-tolyl phenylacetate, CAS Registry Number 101-94-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, methyl decanoate, CAS Registry Number 110-42-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 1-decanol, CAS registry number 112-30-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, clove bud absolute, CAS Registry Number 8000-34-8, RIFM ID 583-F2.1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, nonyl alcohol, CAS Registry Number 143-08-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, methoxy dicyclopentadiene carboxaldehyde, CAS Registry Number 86803-90-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, octahydro-4,7-methano-1H-indenecarbaldehyde, CAS Registry Number 30772-79-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, acetophenone, CAS Registry number 98-86-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, Sage oil, Spanish, CAS Registry Number 8022-56-8, RIFM ID 479-E2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

2nd Update to RIFM fragrance ingredient safety assessment, α-amylcinnamaldehyde, CAS Registry Number 122-40-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Corrigendum to “RIFM fragrance ingredient safety assessment, vanillin isobutyrate, CAS Registry Number 20665-85-4” [Food Chem. Toxicol. 197 Supplement 1 (2024) 115141 ISSN 0278–6915] - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, heptyl alcohol, CAS registry number 111-70-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 4-acetoxy-2,5-dimethyl-3(2H)furanone, CAS Registry Number 4166-20-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isoamyl propionate, CAS Registry Number 105-68-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isobutyl propionate, CAS Registry Number 540-42-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 4-(p-methoxyphenyl)-2-butanone, CAS Registry Number 104-20-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, cis-6-nonenal, CAS registry number 2277-19-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 3-phenylbutanal, CAS registry number 16251-77-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, cyclohexanepropanol, α-ethyl-2,2,6-trimethyl-, CAS Registry Number 60241-52-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, methyl 3,7-dimethyl-6-octenoate, CAS registry number 2270-60-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, (1aα,4α,7aα)-1a,3,3,4,6,6-hexamethyl-1a,2,3,4,5,6,7,7a-octahydronapth[3,3-b]oxirene, CAS Registry Number 94400-98-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, cyclododecyl formate, CAS Registry Number 59052-82-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, (Z)-4-dodecenal, CAS registry number 21944-98-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-phenylpropionaldehyde, CAS registry number 93-53-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 4,5-dihydro-3(2H)thiophenone, CAS Registry Number 1003-04-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 9-undecenal, CAS Registry Number 143-14-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, β-methyl-benzenepentanal, CAS registry number 55066-49-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, nonanal, CAS registry number 124-19-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, trans-4-decen-1-al, CAS Registry Number 65405-70-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isoamyl formate, CAS Registry Number 110-45-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 8-undecenal, CAS registry number 58296-81-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, linalyl isovalerate, CAS Registry Number 1118-27-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, hexanal, CAS Registry Number 66-25-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 4,8-dimethyl-7-nonen-2-ol, CAS Registry Number 40596-76-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 2-ethoxy-4-(methoxymethyl)phenol, CAS Registry Number 5595-79-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS registry number 472-97-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, acetylcarene, CAS Registry Number 3608-11-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 4-heptenal, CAS Registry Number 6728-31-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isoamyl alcohol, CAS Registry Number 123-51-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 2-phenoxyethyl isobutyrate, CAS registry number 103-60-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, linalyl isobutyrate, CAS Registry Number 78-35-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 1-tetradecanol, CAS Registry Number 112-72-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 3-hexenoic acid, CAS Registry Number 4219-24-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, methyl 2-nonynoate, CAS Registry Number 111-80-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 3-(4-methyl-3-cyclohexenyl)butanol, CAS Registry Number 15760-18-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, dihydro-β-ionol, CAS Registry Number 3293-47-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, p-tolylacetaldehyde, CAS Registry Number 104-09-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, β-pinene, CAS Registry Number 127-91-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, geranyl crotonate, CAS Registry Number 56172-46-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-methyl-4(2,2,3-trimethyl-3-cyclopentenyl)butanol, CAS Registry Number 72089-08-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 3-methylbutyl valerate, CAS Registry Number 2050-09-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, octanal, CAS Registry Number 124-13-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, tricyclo[3.3.1.1.(3.7)]decan-2-ol, 4-methyl-8-methylene-, CAS Registry Number 122760-84-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, heptanal, CAS registry number 111-71-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-methylbutyl butyrate, CAS Registry Number 51115-64-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, amyl alcohol, CAS Registry Number 71-41-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, pentanoic acid, 2-methylbutyl ester, CAS Registry Number 55590-83-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 3,4-xylenol, CAS Registry Number 95-65-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-methylbutyl acetate, CAS Registry Number 624-41-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isobutyl butyrate, CAS Registry Number 539-90-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, decanal, CAS registry number 112-31-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, cedryl formate, CAS Registry Number 39900-38-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 4-(4-methoxyphenyl)-3-methylbutan-2-one, CAS Registry Number 67828-19-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 1-(p-methoxyphenyl)-2-propanone, CAS Registry Number 122-84-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, trans-2-hexenyl acetate, CAS Registry Number 2497-18-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, isolongifolene oxide, CAS Registry Number 26619-69-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, p-menth-8-en-2-one, CAS Registry Number 7764-50-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, l-menthyl (R,S)-3-hydroxybutyrate, CAS Registry Number 108766-16-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, butyl alcohol, CAS registry number 71-36-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, tridecanal, CAS registry number 10486-19-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, cedr-8-ene epoxide, CAS Registry Number 13567-39-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, geranyl tiglate, CAS Registry Number 7785-33-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 4′-tert-butyl-2′,6′-dimethylacetophenone, CAS Registry Number 2040-10-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, ethyl trans-2,cis-4-decadienoate, CAS registry number 3025-30-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isoamyl acetate, CAS Registry Number 123-92-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 1-hexadecanol, CAS Registry Number 36653-82-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isobutyl acetate, CAS Registry Number 110-19-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, cis-3-hexenyl salicylate, CAS Registry Number 65405-77-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-methyl-2-hepten-6-ol, CAS registry number 1569-60-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, nopyl acetate, CAS registry number 128-51-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isoamyl butyrate, CAS Registry Number 106-27-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, piperonal, CAS Registry Number 120-57-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, benzothiazole, CAS Registry Number 95-16-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 1-cyclopropylmethyl-4-methoxybenzene, CAS registry number 16510-27-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 3,7-dimethyl-2-methylenocta-6-enal, CAS registry number 22418-66-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, isobutyl alcohol, CAS Registry Number 78-83-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 2-methylpropyl pentanoate, CAS Registry Number 10588-10-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, 2-(3-heptyl)-1,3-dioxolane, CAS Registry Number 4359-47-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, ethyl 2-methyl-3-pentenoate, CAS Registry Number 1617-23-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, vanillin isobutyrate, CAS Registry Number 20665-85-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2025)

Update to RIFM fragrance ingredient safety assessment, 3-methylbutanal diethyl acetal, CAS Registry Number 3842-03-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2025)

RIFM fragrance ingredient safety assessment, (4-methylphenoxy)acetaldehyde, CAS Registry Number 67845-46-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, propyl alcohol, CAS Registry Number 71-23-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, dibenzyl ether, CAS Registry number 103-50-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, β-ionyl acetate, CAS Registry Number 22030-19-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, cinnamyl cinnamate, CAS Registry Number 122-69-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2,6-xylenol, CAS Registry Number 576-26-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, isobutyl formate, CAS registry number 542-55-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, methyl 2-octynoate, CAS Registry Number 111-12-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, cyclohexanone 1,3-butylene glycol ketal, CAS Registry Number 6413-26-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, zingerone, CAS Registry Number 122-48-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-ethoxy-4-[(1-methylethoxy)methyl] phenol, CAS Registry number 96840-56-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, diethyl malonate, CAS registry number 105-53-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 4-(4,8-dimethylnona-3,7-dienyl)pyridine, CAS Registry Number 38462-23-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 1,3-propanediol, 2,2-dimethyl-, 1,3-diacetate, CAS registry number 13431-57-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 3-(cis-3-hexenyloxy)propanenitrile, CAS Registry Number 142653-61-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, isobutyl benzoate, CAS registry number 120-50-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 4-(4-methyl-3-penten-1-yl)-2(5H)-furanone, CAS Registry number 61315-75-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M.L. Dagli; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-butyl-4,4,6-trimethyl-1,3-dioxane, CAS registry number 54546-26-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 1-(2-tert-butyl cyclohexyloxy)-2-butanol, CAS Registry Number 139504-68-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, ethyl 2-methylbutyrate, CAS Registry Number 7452-79-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, benzyl salicylate, CAS registry number 118-58-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, hexyl benzoate, CAS registry number 6789-88-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, methyl isovalerate, CAS Registry Number 556-24-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, cyclohexanecarboxylic acid, CAS Registry Number 98-89-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, ethyl isobutyrate, CAS registry number 97-62-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 6,8-dimethylnonan-2-ol, CAS registry number 70214-77-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, isoamyl benzoate, CAS registry number 94-46-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, methyl isobutyrate, CAS registry number 547-63-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 10-undecenoic acid, heptyl ester, CAS registry number 68141-27-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 3-(4-methylcyclohex-3-enyl)-3-butenyl acetate, CAS registry number 6819-19-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, p-methyl-α-amyl cinnamic aldehyde, CAS Registry Number 84697-09-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, methyl salicylate, CAS registry number 119-36-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, methyl 2-methylbutyrate, CAS Registry Number 868-57-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, amyl salicylate, CAS Registry Number 2050-08-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 1-methyl-2-(1-methylpropyl)cyclohexyl acetate, CAS Registry number 72183-75-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, cis-3-hexenyl benzoate, CAS Registry Number 25152-85-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, isoamyl salicylate, CAS Registry Number 87-20-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]decan-2-one, 8-(1-methylethyl)-, trans-, CAS Registry Number 4625-90-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 4-methyl-2-pentanol, CAS registry number 108-11-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2,6-dimethyl-4-heptanol, CAS registry number 108-82-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, heptyl acetate, CAS registry number 112-06-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-methyl-5-phenylpentanol, CAS Registry Number 25634-93-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, hexyl formate, CAS registry number 629-33-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, hexyl butyrate, CAS Registry Number 2639-63-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, furfural, CAS Registry Number 98-01-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, octyl acetate, CAS Registry Number 112-14-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, octyl formate, CAS registry number 112-32-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]decan-2-one, 8-ethyl-, trans-, CAS Registry Number 91069-40-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, p-mentha-1,8-dien-7-ol, CAS Registry Number 536-59-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 7-isopropyl-1,4-dimethylazulene, CAS registry number 489-84-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 4-isopropyl-1-methylcyclohexene, CAS registry number 29350-67-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, allyl α-ionone, CAS Registry Number 79-78-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, lauryl acetate, CAS Registry Number 112-66-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]decan-2-one, 8-methyl-, CAS Registry number 94201-19-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3-methyl-5-phenylpentanol, CAS Registry Number 55066-48-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, nonyl acetate, CAS registry number 143-13-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3-(methylthio)hexyl acetate, CAS registry number 51755-85-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2,2-dimethyl-3-phenylpropanol, CAS registry number 13351-61-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 5-(cis-3-hexenyl)dihydro-5-methyl-2(3H)furanone, CAS Registry Number 70851-61-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, o-phenyl anisole, CAS registry number 86-26-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, geranyl acetate, CAS registry number 105-87-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, geranyl linalool, CAS registry number 1113-21-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, ionone (mixed isomers), CAS registry number 8013-90-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, ethyl salicylate, CAS Registry Number 118-61-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 4-phenyl-3-buten-2-ol, CAS registry number 17488-65-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, isopropyl acetate, CAS registry number 108-21-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, hexyl propionate, CAS Registry Number 2445-76-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, α-butylcinnamaldehyde, CAS registry number 7492-44-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, decyl acetate, CAS Registry Number 112-17-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, musk ketone, CAS registry number 81-14-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, veratraldehyde, CAS Registry Number 120-14-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, isopropyl butyrate, CAS Registry Number 638-11-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-hydroxybenzoic acid, CAS Registry Number 69-72-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 5-methylfurfural, CAS registry number 620-02-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, hexyl acetate, CAS registry number 142-92-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-methyl-4-phenylpentanol, CAS registry number 92585-24-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 2-methyl-4-phenylbutyraldehyde, CAS Registry Number 40654-82-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, cis-3-hexenal, CAS Registry Number 6789-80-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, pinus nigra oil, CAS Registry Number 8000-26-8, RIFM ID 1068-E2.12 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, cyclohexyl phenylacetate, CAS Registry Number 42288-75-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3,4,5,6,6-pentamethylheptan-2-ol, CAS registry number 87118-95-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 1,3-cyclohexadiene-1-carboxylic acid, 4,6,6-trimethyl-, ethyl ester, CAS Registry Number 100520-15-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2(4H)-benzofuranone, 5,6-dihydro-3,6-dimethyl-, CAS Registry Number 80417-97-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, β-methylphenethyl alcohol, CAS Registry Number 1123-85-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, N-ethyl-N-(3-methylphenyl)propionamide, CAS Registry Number 179911-08-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, allyl cinnamate, CAS Registry number 1866-31-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3-hexene, 1-[(2-methyl-2-propenyl)oxy]- (3Z)-, CAS Registry Number 292605-05-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM natural complex substance (NCS) fragrance ingredient safety assessment, lavandin abrialis, CAS registry number 8022-15-9, RIFM ID 1048554 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, rotundone, CAS Registry Number 18374-76-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, methylheptenol, CAS Registry Number 1335-09-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 1,4-bis(ethoxymethyl)cyclohexane, CAS Registry Number 54889-63-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-, benzoate, CAS Registry Number 55066-54-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-methylbutyl hexanoate, CAS registry Number 2601-13-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, propanoic acid, 2-methyl-, cyclohexyl ester, CAS Registry Number 1129-47-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1,6-nonadien-3-yl acetate, CAS Registry Number 61931-80-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-heptanol, 3,6-dimethyl-, CAS registry number 1247790-47-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, ethyl cyclohexanecarboxylate, CAS Registry Number 3289-28-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, linalyl butyrate, CAS Registry Number 78-36-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 6-butyl-2,4-dimethyldihydropyrane, CAS Registry Number 24237-00-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3,7-dimethyl-7-methoxyoctan-2-ol, CAS registry number 41890-92-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-isopropyl-N,2,3-trimethylbutyramide, CAS registry number 51115-67-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, piperonyl acetate, CAS registry number 326-61-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, α-propylphenethyl alcohol, CAS registry number 705-73-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, allyl heptanoate, CAS registry number 142-19-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-(4-methylphenoxy)ethanol, CAS Registry Number 15149-10-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, nonanoyl 4-hydroxy-3-methoxybenzylamide, CAS Registry Number 2444-46-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, allyl hexanoate, CAS Registry Number 123-68-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, phenethyl alcohol, CAS Registry Number 60-12-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, benzenepropanol, a,ß-dimethyl-, CAS Registry Number 56836-93-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3-(2-oxopropyl)-2-pentylcyclopentanone, CAS Registry Number 40942-73-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 1,3,3-trimethyl-2-norbornanyl acetate, CAS registry number 13851-11-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, tetrahydrogeranial, CAS Registry Number 5988-91-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, isobornyl acetate, CAS Registry Number 125-12-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, nerolidyl acetate (isomer unspecified), CAS registry number 2306-78-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, oxacyclohexadecane-2,13-dione, CAS registry number 38223-29-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, (Z)-octadec-9-enol, CAS registry number 143-28-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, linalyl acetate, CAS registry number 115-95-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 1-naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-, CAS Registry Number 103614-86-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-inden-5-yl pivalate, CAS Registry Number 68039-45-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-inden-5-yl isobutyrate, CAS Registry Number 67634-20-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, tricyclodecanyl acetate, CAS registry number 64001-15-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, isobornyl propionate, CAS Registry Number 2756-56-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, allyl octanoate, CAS Registry Number 4230-97-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, linalyl formate, CAS registry number 115-99-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, nerol oxide, CAS Registry Number 1786-08-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, l-menthyl D-lactate, CAS registry number 59259-38-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, linalyl propionate, CAS registry number 144-39-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, trichloromethyl phenyl carbinyl acetate, CAS Registry number 90-17-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 4-hexen-1-ol, 5-methyl-2-(1-methylethenyl)-, CAS registry number 58461-27-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, dihydro-α-terpineol, CAS Registry Number 498-81-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 2-hexylcyclopentanone, CAS registry number 13074-65-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-methyl-4-phenyl-2-butyl isobutyrate, CAS registry number 10031-71-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, d,l-menthone 1,2-glycerol ketal, CAS Registry Number 63187-91-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 4-cyclohexyl-2-methyl-2-butanol, CAS registry number 83926-73-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 4′-hydroxy-3′-methoxyacetophenone, CAS Registry Number 498-02-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 2,2,4-trimethyl-4-phenyl-butane-nitrile, CAS Registry Number 75490-39-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, thymol, CAS Registry Number 89-83-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, ethyl cinnamate, CAS Registry Number 103-36-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3-methyl-2-butenyl benzoate, CAS Registry Number 5205-11-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, methylcyclooctyl carbonate, CAS Registry Number 61699-38-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-p-tolylethanol, CAS registry number 699-02-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1,3,6-octatriene, CAS Registry Number 13877-91-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 1,1-dimethyl-2-phenylethyl isobutyrate, CAS Registry Number 59354-71-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, amyl cinnamate, CAS Registry Number 3487-99-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-methyl-4-phenyl-2-butanol, CAS Registry Number 103-05-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, benzenepropanenitrile, 4-ethyl-α,α.-dimethyl-, CAS Registry Number 134123-93-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, methyl 2,4-dihydroxy-m-toluate, CAS Registry Number 33662-58-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2H-1,5-benzodioxepin-3(4H)-one, 7-(1-methylethyl)-, CAS Registry Number 950919-28-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, ethyl 2-ethylhexanoate, CAS Registry Number 2983-37-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, cyclohexyl salicylate, CAS registry number 25485-88-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment,α-methylbenzyl alcohol, CAS registry number 98-85-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 4-isopropylcyclohexanol, CAS Registry Number 4621-04-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, α,α-dimethylphenethyl alcohol, CAS Registry Number 100-86-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, citronellyl ethyl oxalate, CAS Registry Number 60788-25-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, ethyl 2-tert-butylcyclohexyl carbonate, CAS Registry Number 67801-64-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, ethyl 2,3,6-trimethylcyclohexyl carbonate, CAS Registry Number 93981-50-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 3-octyl acetate, CAS registry number 4864-61-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, exo-2-[(1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)oxy]ethanol, CAS Registry Number 7070-15-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 2-propanol, reaction products with boron trifluoride and 5-ethylidenebicyclo[2.2.1]hept-2-ene, CAS registry number 90530-04-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 1-propanol, 2-methyl-3-[(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yl)oxy]-, CAS Registry Number 128119-70-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 1,3-nonanediol acetate (mixed esters), CAS Registry Number 1322-17-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 3,12-tridecadienenitrile, CAS Registry Number 134769-33-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, hexanoic acid, 4-methyl-, CAS registry number 1561-11-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 4-ethyloctanoic acid, CAS registry number 16493-80-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 2-methylhexanoic acid, CAS registry number 4536-23-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 2-methylheptanoic acid, CAS registry number 1188-02-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, butyl 2-methylvalerate, CAS Registry Number 6297-41-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, N,N-diethyloctamide, CAS registry number 996-97-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, phenethyl salicylate, CAS Registry Number 87-22-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, benzonitrile, 3,4-dimethyl-, CAS Registry Number 22884-95-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 4-allyl-2-methoxyphenyl benzyl ether, CAS Registry Number 57371-42-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 3,6-nonadien-1-ol, CAS Registry Number 76649-25-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, ethyl 2-methylpentanoate, CAS Registry Number 39255-32-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, linalyl cinnamate, CAS registry number 78-37-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, ethyl 3,5,5-trimethylhexanoate, CAS Registry Number 67707-75-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 4-methyloctanoic acid, CAS Registry Number 54947-74-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, butyl 10-undecenoate, CAS Registry Number 109-42-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 2-methylvaleric acid, CAS Registry Number 97-61-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 3-methylpentanoic acid, CAS registry number 105-43-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 4-methylnonanoic acid, CAS Registry Number 45019-28-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 2-ethylbutyric acid, CAS Registry Number 88-09-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, cis- and trans-p-1(7),8-menthadien-2-yl acetate, CAS registry number 71660-03-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, diethyldimethylcyclohex-2-en-1-one, CAS Registry Number 68845-36-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3-phenyl-3-buten-1-yl acetate, CAS Registry Number 7306-12-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, spiro[1,3-dioxolane-2,8′(5′H)-[2H-2,4a]methanonaphthalene],hexahydro-1′,1′,5′,5′-tetramethyl-, [2′S-(2′α,4′aα,8′aα)]-, CAS Registry Number 154171-77-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, p-tolyl alcohol, CAS Registry Number 589-18-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 5-ethyl-2,3,4,5-tetramethylcyclohexen-1-one, CAS Registry Number 17369-60-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, cyclohexanol, 2-methoxy-4-propyl-, CAS Registry Number 23950-98-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, ethyl 10-undecenoate, CAS Registry Number 692-86-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, p-tert-butyldihydrocinnamaldehyde, CAS Registry Number 18127-01-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, isoeugenyl phenylacetate, CAS registry number 120-24-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3-(p-isopropylphenyl)propionaldehyde, CAS registry number 7775-00-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 3,3,5-trimethylcyclohexyl ethyl ether, CAS Registry Number 67583-77-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, triethyltrimethyl-2-cyclohexen-1-one, CAS Registry Number 68845-35-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, germacrene D, CAS Registry Number 23986-74-5 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 5-methyl-2-thiophenecarboxaldehyde, CAS registry number 13679-70-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, isoeugenyl benzyl ether, CAS Registry Number 120-11-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, pentyl benzoate, CAS Registry Number 2049-96-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, ethyl vanillin isobutyrate, CAS Registry Number 188417-26-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, l-carvone, CAS Registry Number 6485-40-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, butyl benzoate, CAS Registry Number 136-60-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, p-isopropyl phenylacetaldehyde, CAS Registry Number 4395-92-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, cyclohexane, 1-(1,1-dimethylpropyl)-4-ethoxy-, cis-, CAS Registry Number 181258-87-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 4-methyl-3-decen-5-ol, CAS Registry Number 81782-77-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, isoeugenol, CAS registry number 97-54-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 10-undecen-1-yl acetate, CAS Registry Number 112-19-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 2-methyl-2-pentenoic acid, CAS Registry Number 16957-70-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 6,10-dodecadienal, 3,7,11-trimethyl-, (3S,6E)-, CAS registry number 194934-66-2 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, cuminyl nitrile, CAS registry number 13816-33-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, (Z,Z)-1,1'-[ethylidenebis(oxy)]di(hex-3-ene), CAS Registry number 63449-64-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, ethyl benzoate, CAS Registry Number 93-89-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, 5-methyl-5-phenyl-3-hexanone, CAS Registry Number 4927-36-0 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, (E)-1-(1-methoxypropoxy)hex-3-ene, CAS Registry Number 97358-54-8 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, methyl undec-10-enoate, CAS registry number 111-81-9 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, acetaldehyde ethyl cis-3-hexenyl acetal, CAS Registry Number 28069-74-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, α-amylcinnamaldehyde, CAS Registry Number 122-40-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 9-decenyl acetate, CAS Registry Number 50816-18-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, phenol, 4-(3,6-dihydro-4-methyl-2H-pyran-2-yl)-2-methoxy-, CAS Registry Number 128489-02-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, eucalyptol, CAS Registry Number 470-82-6 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, pyridine, 5-hexyl-2-methyl-, CAS Registry Number 710-40-7 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, dodecahydro-3,8,8,11a-tetramethyl-5H-3,5a-epoxynaphth[2,1-c]oxepin, CAS Registry Number 57345-19-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

Update to RIFM fragrance ingredient safety assessment, 2-methyl-3-buten-2-ol, CAS Registry Number 115-18-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, o-toluenethiol, CAS Registry Number 137-06-4 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, benzoic acid, 2-hydroxy-5-methyl-, methyl ester, CAS Registry Number 22717-57-3 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)

RIFM fragrance ingredient safety assessment, linalool oxide, CAS Registry Number 1365-19-1 - A.M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Freidrich; G.A. Burton; M.A. Cancellieri; H. Chon; M.L. Dagli; W. Dekant; C. Deodhar; et al. (Food and Chemical Toxicology, 2024)