Geographic and subsequent biotic isolations led to a diversity anomaly of section Heterotropa (genus Asarum : Aristolochiaceae) in insular versus continental regions of the Sino‐Japanese Floristic Region - Daiki Takahashi; Shota Sakaguchi; Yu Feng; Yuji Isagi; Ying‐Xiong Qiu; Pan Li; Rui‐Sen Lu; Chang‐Tse Lu; Shih‐Wen Chung; Yang‐Shan Lin; Yun‐Chao Chen; Atsushi J. Nagano; et al. (Journal of Biogeography, 2021)
Aim The Sino‐Japanese Floristic Region has extremely high species diversity with respect to temperate plants; however, the reasons for this diversity are poorly understood because most studies have only considered geographic isolation caused by climatic oscillations. In some plant groups, high floral trait diversity and uneven species diversity between insular systems and the continental area suggest other factors may have important roles too. The primary purpose of this study is to reveal how abiotic and biotic factors have shaped the species diversity anomaly of Heterotropa between the insular systems and the continental area. Location The Sino‐Japanese Floristic Region. Taxon Section Heterotropa (genus Asarum ; Aristolochiaceae). Methods Using ddRAD‐seq and chloroplast genome data, we built a time‐calibrated phylogenetic tree including 79 species. We estimated the patterns of floral traits (flowering time and floral size) evolution using macroevolutionary modelling, and tested the correlation of speciation rate with the trait evolution rates. Finally, we estimated the isolation factors of all taxa pairs and sister‐taxa pairs based on distribution range and floral traits. Results Phylogenetic analysis indicated that Heterotropa was diverged into two clades (continental clade and insular clade) in the Miocene, and the major subclades corresponded to geographic entities. Most rate shifts accelerating floral trait's evolution occurred during the Pleistocene period. Evolution rate of floral traits showed positive correlation with the speciation rate. Large proportion of taxa in the insular clade are distributed allopatrically. Several sister pairs showed floral trait divergence with geographic overlap. Main Conclusions The diversification of Heterotropa appears to have been triggered by geographic and climatic events, and subsequent repeated floral trait evolution with and without geographic isolation. Furthermore, the high species diversity in the insular systems would have been formed by the repeated range fragmentations and contractions. Our study demonstrates the importance of multidimensional studies to understand the diversification process of temperate plants in the Sino‐Japanese Floristic Region.

Molecular mapping of quantitative disease resistance loci for soybean partial resistance to Phytophthora sansomeana - Feng Lin; Wenlong Li; Austin G. McCoy; Xuan Gao; Paul J. Collins; Na Zhang; Zixiang Wen; Sizhe Cao; Shabir H. Wani; Cuihua Gu; Martin I. Chilvers; Dechun Wang (Theoretical and Applied Genetics, 2021)

Activation of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) with Lidocaine Provokes Pyroptosis of Glioblastoma Cells - B. Zhou; Y. Lin; S. Chen; J. Cai; Z. Luo; S. Yu; J. Lu (Bulletin of Experimental Biology and Medicine, 2021)

Traits, strategies, and niches of liana species in a tropical seasonal rainforest - Qi Liu; Frank J. Sterck; Jiao-Lin Zhang; Arne Scheire; Evelien Konings; Min Cao; Li-Qing Sha; Lourens Poorter (Oecologia, 2021)
Plant functional traits and strategies hold the promise to explain species distribution, but few studies have linked multiple traits to multiple niche dimensions (i.e., light, water, and nutrients). Here, we analyzed for 29 liana species in a Chinese tropical seasonal rainforest how: (1) trait associations and trade-offs lead to different plant strategies; and (2) how these traits shape species’ niche dimensions. Eighteen functional traits related to light, water, and nutrient use were measured and species niche dimensions were quantified using species distribution in a 20-ha plot combined with data on canopy gaps, topographic water availability, and soil nutrients. We found a tissue toughness spectrum ranging from soft to hard tissues along which species also varied from acquisitive to conservative water use, and a resource acquisition spectrum ranging from low to high light capture and nutrient use. Intriguingly, each spectrum partly reflected the conservative–acquisitive paradigm, but at the same time, the tissue toughness and the resource acquisition spectrum were uncoupled. Resource niche dimensions were better predicted by individual traits than by multivariate plant strategies. This suggests that trait components that underlie multivariate strategy axes, rather than the plant strategies themselves determine species distributions. Different traits were important for different niche dimensions. In conclusion, plant functional traits and strategies can indeed explain species distributions, but not in a simple and straight forward way. Although the identification of global plant strategies has significantly advanced the field, this research shows that global, multivariate generalizations are difficult to translate to local conditions, as different components of these strategies are important under different local conditions.

A biallelic variant in CLRN2 causes non-syndromic hearing loss in humans - Barbara Vona; Neda Mazaheri; Sheng-Jia Lin; Lucy A. Dunbar; Reza Maroofian; Hela Azaiez; Kevin T. Booth; Sandrine Vitry; Aboulfazl Rad; Franz Rüschendorf; Pratishtha Varshney; Ben Fowler; et al. (Human Genetics, 2021)
Deafness, the most frequent sensory deficit in humans, is extremely heterogeneous with hundreds of genes involved. Clinical and genetic analyses of an extended consanguineous family with pre-lingual, moderate-to-profound autosomal recessive sensorineural hearing loss, allowed us to identify CLRN2, encoding a tetraspan protein, as a new deafness gene. Homozygosity mapping followed by exome sequencing identified a 14.96 Mb locus on chromosome 4p15.32p15.1 containing a likely pathogenic missense variant in CLRN2 (c.494C > A, NM_001079827.2) segregating with the disease. Using in vitro RNA splicing analysis, we show that the CLRN2 c.494C > A variant leads to two events: (1) the substitution of a highly conserved threonine (uncharged amino acid) to lysine (charged amino acid) at position 165, p.(Thr165Lys), and (2) aberrant splicing, with the retention of intron 2 resulting in a stop codon after 26 additional amino acids, p.(Gly146Lysfs*26). Expression studies and phenotyping of newly produced zebrafish and mouse models deficient for clarin 2 further confirm that clarin 2, expressed in the inner ear hair cells, is essential for normal organization and maintenance of the auditory hair bundles, and for hearing function. Together, our findings identify CLRN2 as a new deafness gene, which will impact future diagnosis and treatment for deaf patients.

Latest Miocene restriction of the Mediterranean Outflow Water: a perspective from the Gulf of Cádiz - Zhi Lin Ng; F. Javier Hernández-Molina; Débora Duarte; Francisco J. Sierro; Santiago Ledesma; Michael Rogerson; Estefanía Llave; Cristina Roque; M. Amine Manar (Geo-Marine Letters, 2021)
The Mediterranean-Atlantic water mass exchange provides the ideal setting for deciphering the role of gateway evolution in ocean circulation. However, the dynamics of Mediterranean Outflow Water (MOW) during the closure of the Late Miocene Mediterranean-Atlantic gateways are poorly understood. Here, we define the sedimentary evolution of Neogene basins from the Gulf of Cádiz to the West Iberian margin to investigate MOW circulation during the latest Miocene. Seismic interpretation highlights a middle to upper Messinian seismic unit of transparent facies, whose base predates the onset of the Messinian salinity crisis (MSC). Its facies and distribution imply a predominantly hemipelagic environment along the Atlantic margins, suggesting an absence or intermittence of MOW preceding evaporite precipitation in the Mediterranean, simultaneous to progressive gateway restriction. The removal of MOW from the Mediterranean-Atlantic water mass exchange reorganized the Atlantic water masses and is correlated to a severe weakening of the Atlantic Meridional Overturning Circulation (AMOC) and a period of further cooling in the North Atlantic during the latest Miocene.

Low diversity of a key phytoplankton group along the West Antarctic Peninsula - Michael S. Brown; Jeff S. Bowman; Yajuan Lin; Colette J. Feehan; Carly M. Moreno; Nicolas Cassar; Adrian Marchetti; Oscar M. Schofield (Limnology and Oceanography, 2021)
The West Antarctic Peninsula (henceforth “Peninsula”) is experiencing rapid warming and melting that is impacting the regional marine food web. The primary phytoplankton groups along the Peninsula are diatoms and cryptophytes. Relative to diatoms, there has been little focus on regional cryptophytes, and thus our understanding of their diversity and ecology is limited, especially at the species level. This gap is important, as diatoms and cryptophytes play distinct roles in the regional marine food web and biogeochemistry. Here, we use a phylogenetic placement approach with 18S rRNA gene amplicon sequence variants to assess surface ocean cryptophyte diversity and its drivers at a high taxonomic resolution along the Peninsula. Data were collected over 5 years (2012–2016) during the regional research cruises of the Palmer Long‐Term Ecological Research program. Our results indicate that there are two major cryptophyte taxa along the Peninsula, consisting of distinct Geminigera spp., which in aggregate always comprise nearly 100% of the cryptophyte community (indicating low taxa evenness). The primary taxon dominates the cryptophyte community across all samples/years, which span a broad range of oceanographic conditions. A shift in cryptophyte community composition between a lower (higher) primary (secondary) taxon percentage is associated with distinct oceanographic conditions, including lower (higher) temperature, salinity, nutrients, and cryptophyte relative abundance (phytoplankton biomass and diatom relative abundance). These results emphasize the need for a full characterization of the ecology of these two taxa, as it is predicted that cryptophytes will increase along the Peninsula given projections of continued regional environmental change.

Photoperiod decelerates the advance of spring phenology of six deciduous tree species under climate warming - Lin Meng; Yuyu Zhou; Lianhong Gu; Andrew D. Richardson; Josep Peñuelas; Yongshuo Fu; Yeqiao Wang; Ghasserm R. Asrar; Hans J. De Boeck; Jiafu Mao; Yongguang Zhang; Zhuosen Wang (Global Change Biology, 2021)
Vegetation phenology in spring has substantially advanced under climate warming, consequently shifting the seasonality of ecosystem process and altering biosphere–atmosphere feedbacks. However, whether and to what extent photoperiod (i.e., daylength) affects the phenological advancement is unclear, leading to large uncertainties in projecting future phenological changes. Here we examined the photoperiod effect on spring phenology at a regional scale using in situ observation of six deciduous tree species from the Pan European Phenological Network during 1980–2016. We disentangled the photoperiod effect from the temperature effect (i.e., forcing and chilling) by utilizing the unique topography of the northern Alps of Europe (i.e., varying daylength but uniform temperature distribution across latitudes) and examining phenological changes across latitudes. We found prominent photoperiod‐induced shifts in spring leaf‐out across latitudes (up to 1.7 days per latitudinal degree). Photoperiod regulates spring phenology by delaying early leaf‐out and advancing late leaf‐out caused by temperature variations. Based on these findings, we proposed two phenological models that consider the photoperiod effect through different mechanisms and compared them with a chilling model. We found that photoperiod regulation would slow down the advance in spring leaf‐out under projected climate warming and thus mitigate the increasing frost risk in spring that deciduous forests will face in the future. Our findings identify photoperiod as a critical but understudied factor influencing spring phenology, suggesting that the responses of terrestrial ecosystem processes to climate warming are likely to be overestimated without adequately considering the photoperiod effect.

Individual Microcystis colonies harbour distinct bacterial communities that differ by Microcystis oligotype and with time - Derek J. Smith; James Y. Tan; McKenzie A. Powers; Xiaoxia N. Lin; Timothy W. Davis; Gregory J. Dick (Environmental Microbiology, 2021)
Summary Interactions between bacteria and phytoplankton in the phycosphere have impacts at the scale of whole ecosystems, including the development of harmful algal blooms. The cyanobacterium Microcystis causes toxic blooms that threaten freshwater ecosystems and human health globally. Microcystis grows in colonies that harbour dense assemblages of other bacteria, yet the taxonomic composition of these phycosphere communities and the nature of their interactions with Microcystis are not well characterized. To identify the taxa and compositional variance within Microcystis phycosphere communities, we performed 16S rRNA V4 region amplicon sequencing on individual Microcystis colonies collected biweekly via high‐throughput droplet encapsulation during a western Lake Erie cyanobacterial bloom. The Microcystis phycosphere communities were distinct from microbial communities in whole water and bulk phytoplankton seston in western Lake Erie but lacked ‘core’ taxa found across all colonies. However, dissimilarity in phycosphere community composition correlated with sampling date and the Microcystis 16S rRNA oligotype. Several taxa in the phycosphere were specific to and conserved with Microcystis of a single oligotype or sampling date. Together, this suggests that physiological differences between Microcystis strains, temporal changes in strain phenotypes, and the composition of seeding communities may impact community composition of the Microcystis phycosphere.

Targeted deletion of HAI-1 increases prostasin proteolysis but decreases matriptase proteolysis in human keratinocytes - Dajun D. Lu; Yayun Gu; Sheng-Wen A. Li; Robert J. Barndt; Shih-Ming Huang; Jehng-Kang Wang; Hui Chen Su; Michael D. Johnson; Chen-Yong Lin (Human Cell, 2021)

Human endothelial colony-forming cells provide trophic support for pluripotent stem cell-derived cardiomyocytes via distinctively high expression of neuregulin-1 - Xuechong Hong; Nicholas Oh; Kai Wang; Joseph Neumeyer; Chin Nien Lee; Ruei-Zeng Lin; Breanna Piekarski; Sitaram Emani; Arin K. Greene; Ingeborg Friehs; Pedro J. del Nido; Juan M. Melero-Martin (Angiogenesis, 2021)

Recognize fish as food in policy discourse and development funding - Abigail Bennett; Xavier Basurto; John Virdin; Xinyan Lin; Samantha J. Betances; Martin D. Smith; Edward H. Allison; Barbara A. Best; Kelly D. Brownell; Lisa M. Campbell; Christopher D. Golden; Elizabeth Havice; et al. (Ambio, 2021)
The international development community is off-track from meeting targets for alleviating global malnutrition. Meanwhile, there is growing consensus across scientific disciplines that fish plays a crucial role in food and nutrition security. However, this ‘fish as food’ perspective has yet to translate into policy and development funding priorities. We argue that the traditional framing of fish as a natural resource emphasizes economic development and biodiversity conservation objectives, whereas situating fish within a food systems perspective can lead to innovative policies and investments that promote nutrition-sensitive and socially equitable capture fisheries and aquaculture. This paper highlights four pillars of research needs and policy directions toward this end. Ultimately, recognizing and working to enhance the role of fish in alleviating hunger and malnutrition can provide an additional long-term development incentive, beyond revenue generation and biodiversity conservation, for governments, international development organizations, and society more broadly to invest in the sustainability of capture fisheries and aquaculture.

From zero to infinity: Minimum to maximum diversity of the planet by spatio‐parametric Rao’s quadratic entropy - Duccio Rocchini; Matteo Marcantonio; Daniele Da Re; Giovanni Bacaro; Enrico Feoli; Giles M. Foody; Reinhard Furrer; Ryan J. Harrigan; David Kleijn; Martina Iannacito; Jonathan Lenoir; Meixi Lin; et al. (Global Ecology and Biogeography, 2021)
Aim The majority of work done to gather information on the Earth's biodiversity has been carried out using in‐situ data, with known issues related to epistemology (e.g., species determination and taxonomy), spatial uncertainty, logistics (time and costs), among others. An alternative way to gather information about spatial ecosystem variability is the use of satellite remote sensing. It works as a powerful tool for attaining rapid and standardized information. Several metrics used to calculate remotely sensed diversity of ecosystems are based on Shannon’s information theory, namely on the differences in relative abundance of pixel reflectances in a certain area. Additional metrics like the Rao’s quadratic entropy allow the use of spectral distance beside abundance, but they are point descriptors of diversity, that is they can account only for a part of the whole diversity continuum. The aim of this paper is thus to generalize the Rao’s quadratic entropy by proposing its parameterization for the first time. Innovation The parametric Rao’s quadratic entropy, coded in R, (a) allows the representation of the whole continuum of potential diversity indices in one formula, and (b) starting from the Rao’s quadratic entropy, allows the explicit use of distances among pixel reflectance values, together with relative abundances. Main conclusions The proposed unifying measure is an integration between abundance‐ and distance‐based algorithms to map the continuum of diversity given a satellite image at any spatial scale. Being part of the rasterdiv R package, the proposed method is expected to ensure high robustness and reproducibility.

Structure of SARS-CoV-2 main protease in the apo state - Xuelan Zhou; Fanglin Zhong; Cheng Lin; Xiaohui Hu; Yan Zhang; Bing Xiong; Xiushan Yin; Jinheng Fu; Wei He; Jingjing Duan; Yang Fu; Huan Zhou; et al. (Science China Life Sciences, 2021)

Lack of resemblance between Myhre syndrome and other “segmental progeroid” syndromes warrants restraint in applying this classification - Angela E. Lin; Nicola Brunetti-Pierri; Bert Callewaert; Valérie Cormier-Daire; Sofia Douzgou; T. Bernard Kinane; Mark E. Lindsay; Lois J. Starr (GeroScience, 2021)

A global collaboration to study intimate partner violence-related head trauma: The ENIGMA consortium IPV working group - Carrie Esopenko; Jessica Meyer; Elisabeth A. Wilde; Amy D. Marshall; David F. Tate; Alexander P. Lin; Inga K. Koerte; Kimberly B. Werner; Emily L. Dennis; Ashley L. Ware; Nicola L. de Souza; Deleene S. Menefee; et al. (Brain Imaging and Behavior, 2021)

The ENIGMA sports injury working group:– an international collaboration to further our understanding of sport-related brain injury - Inga K. Koerte; Carrie Esopenko; Sidney R. Hinds; Martha E. Shenton; Elena M. Bonke; Jeffrey J. Bazarian; Kevin C. Bickart; Erin D. Bigler; Sylvain Bouix; Thomas A. Buckley; Meeryo C. Choe; Paul S. Echlin; et al. (Brain Imaging and Behavior, 2021)
Sport-related brain injury is very common, and the potential long-term effects include a wide range of neurological and psychiatric symptoms, and potentially neurodegeneration. Around the globe, researchers are conducting neuroimaging studies on primarily homogenous samples of athletes. However, neuroimaging studies are expensive and time consuming, and thus current findings from studies of sport-related brain injury are often limited by small sample sizes. Further, current studies apply a variety of neuroimaging techniques and analysis tools which limit comparability among studies. The ENIGMA Sports Injury working group aims to provide a platform for data sharing and collaborative data analysis thereby leveraging existing data and expertise. By harmonizing data from a large number of studies from around the globe, we will work towards reproducibility of previously published findings and towards addressing important research questions with regard to diagnosis, prognosis, and efficacy of treatment for sport-related brain injury. Moreover, the ENIGMA Sports Injury working group is committed to providing recommendations for future prospective data acquisition to enhance data quality and scientific rigor.

Evaluation of the Possible Contribution of Phenylpropanoids to Potato Discoloration - Sen Lin; Moehninsi; Maximilian J. Feldman; Duroy A. Navarre (American Journal of Potato Research, 2021)

The influence of vector‐borne disease on human history: socio‐ecological mechanisms - Tejas S. Athni; Marta S. Shocket; Lisa I. Couper; Nicole Nova; Iain R. Caldwell; Jamie M. Caldwell; Jasmine N. Childress; Marissa L. Childs; Giulio A. De Leo; Devin G. Kirk; Andrew J. MacDonald; Kathryn Olivarius; et al. (Ecology Letters, 2021)
Vector‐borne diseases (VBDs) are embedded within complex socio‐ecological systems. While research has traditionally focused on the direct effects of VBDs on human morbidity and mortality, it is increasingly clear that their impacts are much more pervasive. VBDs are dynamically linked to feedbacks between environmental conditions, vector ecology, disease burden, and societal responses that drive transmission. As a result, VBDs have had profound influence on human history. Mechanisms include: (1) killing or debilitating large numbers of people, with demographic and population‐level impacts; (2) differentially affecting populations based on prior history of disease exposure, immunity, and resistance; (3) being weaponised to promote or justify hierarchies of power, colonialism, racism, classism and sexism; (4) catalysing changes in ideas, institutions, infrastructure, technologies and social practices in efforts to control disease outbreaks; and (5) changing human relationships with the land and environment. We use historical and archaeological evidence interpreted through an ecological lens to illustrate how VBDs have shaped society and culture, focusing on case studies from four pertinent VBDs: plague, malaria, yellow fever and trypanosomiasis. By comparing across diseases, time periods and geographies, we highlight the enormous scope and variety of mechanisms by which VBDs have influenced human history.

Use of Exposomic Methods Incorporating Sensors in Environmental Epidemiology - Brett T. Doherty; Jeremy P. Koelmel; Elizabeth Z. Lin; Megan E. Romano; Krystal J. Godri Pollitt (Current Environmental Health Reports, 2021)

Characterization and validation of QTLs for adult plant stripe rust resistance in Chinese wheat landrace Dabaimai - M. Y. Wang; M. R. Xu; F. T. Wang; S. J. A. Shah; J. Feng; R. M. Lin; S. C. Xu (Cereal Research Communications, 2021)

Genetic diversity and life‐history traits of bonefish Albula spp. from the Red Sea - Collin T. Williams; Ashlie J. McIvor; Elizabeth M. Wallace; Yu‐Jia Lin; Michael L. Berumen (Journal of Fish Biology, 2021)
The management of bonefishes Albula spp. has been hindered by unresolved species distributions and a general lack of life‐history information. This study provides the first genetic species identifications of Albula spp. from the northern Indian Ocean. The roundjaw bonefish Albula glossodonta was documented in the Red Sea, and the smallscale bonefish A. oligolepis was identified in the Gulf of Aden with no evidence supporting sympatry. Estimates of genetic differentiation indicate three closely related lineages of A. glossodonta in the Red Sea, Indian Ocean and Pacific Ocean (Red Sea‐Pacific Ocean, F st = 0.295; Red Sea‐Seychelles, F st = 0.193; Pacific Ocean‐Seychelles, F st = 0.141). In addition, the authors provide the first life‐history information of Albula spp. in the Indian Ocean. Age‐based growth models of A. glossodonta from the Red Sea demonstrated statistically significant differences compared to previously published data from the Pacific Ocean. Spawning activity during winter months was derived from gonado‐somatic index values of A. glossodonta from the Red Sea and corresponded with spawning seasonality previously documented for the species in the Pacific Ocean. The results of this study aid in refining biogeographical uncertainties of Albula spp. and illustrate the importance of collecting regional growth information for subsequent management of A. glossodonta .

Preformulation Characterization of Griffithsin, a Biopharmaceutical Candidate for HIV Prevention - Lindsay F. Kramzer; Krystal T. Hamorsky; Phillip W. Graebing; Lin Wang; Joshua L. Fuqua; Nobuyuki Matoba; Amanda B. Lasnik; Bernard J. Moncla; Junmei Zhang; Kenneth E. Palmer; Lisa C. Rohan (AAPS PharmSciTech, 2021)

Warming Iron-Limited Oceans Enhance Nitrogen Fixation and Drive Biogeographic Specialization of the Globally Important Cyanobacterium Crocosphaera - Nina Yang; Carlin A. Merkel; Yu-An Lin; Naomi M. Levine; Nicholas J. Hawco; Hai-Bo Jiang; Ping-Ping Qu; Michelle A. DeMers; Eric A. Webb; Fei-Xue Fu; David A. Hutchins (Frontiers in Marine Science, 2021)
Primary productivity in the nutrient-poor subtropical ocean gyres depends on new nitrogen inputs from nitrogen fixers that convert inert dinitrogen gas into bioavailable forms. Temperature and iron (Fe) availability constrain marine nitrogen fixation, and both are changing due to anthropogenic ocean warming. We examined the physiological responses of the globally important marine nitrogen fixer, Crocosphaera watsonii across its full thermal range as a function of iron availability. At the lower end of its thermal range, from 22 to 27°C, Crocosphaera growth, nitrogen fixation, and Nitrogen-specific Iron Use Efficiencies (N-IUEs, mol N fixed hour –1 mol Fe –1 ) increased with temperature. At an optimal growth temperature of 27°C, N-IUEs were 66% higher under iron-limited conditions than iron-replete conditions, indicating that low-iron availability increases metabolic efficiency. However, Crocosphaera growth and function decrease from 27 to 32°C, temperatures that are predicted for an increasing fraction of tropical oceans in the future. Altogether, this suggests that Crocosphaera are well adapted to iron-limited, warm waters, within prescribed limits. A model incorporating these results under the IPCC RCP 8.5 warming scenario predicts that Crocosphaera N-IUEs could increase by a net 47% by 2100, particularly in higher-latitude waters. These results contrast with published responses of another dominant nitrogen fixer ( Trichodesmium ), with predicted N-IUEs that increase most in low-latitude, tropical waters. These models project that differing responses of Crocosphaera and Trichodesmium N-IUEs to future warming of iron-limited oceans could enhance their current contributions to global marine nitrogen fixation with rates increasing by ∼91 and ∼22%, respectively, thereby shifting their relative importance to marine new production and also intensifying their regional divergence. Thus, interactive temperature and iron effects may profoundly transform existing paradigms of nitrogen biogeochemistry and primary productivity in open ocean regimes.

The stratigraphic significance of early Cambrian (Series 2, Stage 4) trilobites from the Smith Bay Shale near Freestone Creek, Kangaroo Island - J. B. Jago; C. J. Bentley; J. R. Paterson; J. D. Holmes; T. R. Lin; X. W. Sun (Australian Journal of Earth Sciences, 2021)

Fracture Propagation of Rock like Material with a Fluid-Infiltrated Pre-existing Flaw Under Uniaxial Compression - C. Wei; B. Zhang; W. Zhu; S. Wang; J. Li; ·L. Yang; C. Lin (Rock Mechanics and Rock Engineering, 2021)

A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization - Jinying Chen; Fan-Li Lin; Jacqueline Y. K. Leung; Leilei Tu; Jiang-Hui Wang; Yu-Fan Chuang; Fan Li; Hsin-Hui Shen; Gregory J. Dusting; Vickie H. Y. Wong; Leszek Lisowski; Alex W. Hewitt; et al. (Angiogenesis, 2021)

Sea Urchins Play an Increasingly Important Role for Coral Resilience Across Reefs in Taiwan - Viet D. H. Dang; Pak-Yin Cheung; Chia-Ling Fong; Aziz J. Mulla; Jia-Ho Shiu; Che-Hung Lin; Yoko Nozawa (Frontiers in Marine Science, 2020)
Herbivores are an important functional group that control algae, create new space, and promote recruitment for coral recovery. However, on many coral reefs, overfishing has greatly decreased the density of herbivores, especially fishes and gastropods, impairing coral resilience. On such overfished reefs, remnant herbivores that are not target species of local fisheries, e.g., sea urchins, are expected to play an increasingly important role, yet few studies, except for those in the Caribbean and Kenya have examined non-fish herbivores in relation to coral resilience. Here, we conducted field surveys at 30 sites along three coral reefs in Taiwan between 2016 and 2017, to examine the relative importance of six key factors for coral resilience: herbivore abundance (fishes, gastropods, sea urchins), coral cover, macroalgal cover, habitat complexity, water depth, and wave exposure. The density of juvenile coral was used as a proxy of coral resilience. Diadematid sea urchins ( Echinothrix spp. and Diadema spp.) dominated most sites (19 of 30 sites) and multivariable regression models showed sea urchin density as the best positive predictor of coral juvenile density. The results elucidated the increasing role diadematid sea urchins play as remnant herbivores on overfished coral reefs in Taiwan. Given that overfishing is a widespread issue, this phenomenon may be occurring globally. More studies are needed to examine the role of remnant, but often ignored, sea urchin herbivory on coral resilience. Reef managers should consider monitoring locally remnant herbivores and incorporating them into management strategies.

Magnesium biofortification of Italian ryegrass (Lolium multiflorum L.) via agronomy and breeding as a potential way to reduce grass tetany in grazing ruminants - Diriba B. Kumssa; J. Alan Lovatt; Neil S. Graham; Sarah Palmer; Rory Hayden; Lolita Wilson; Scott D. Young; R. Murray Lark; Beth Penrose; E. Louise Ander; Russell Thompson; Lin-Xi Jiang; et al. (Plant and Soil, 2020)
Aim Magnesium (Mg) deficiency (known as grass tetany) is a serious metabolic disorder that affects grazing ruminants. We tested whether Mg-fertiliser can increase Mg concentration of Italian ryegrasses ( Lolium multiflorum L.) including a cultivar (cv. Bb2067; ‘Magnet’), bred to accumulate larger concentrations of Mg. Methods Under controlled environment (CE) conditions, three cultivars (cv. Bb2067, cv. Bb2068, cv. RvP) were grown in low-nutrient compost at six fertiliser rates (0–1500 μM MgCl 2 .6H 2 O). Under field conditions, the three cultivars in the CE condition and cv. Alamo were grown at two sites, and four rates of MgSO 4 fertiliser application rates (0–200 kg ha −1 MgO). Multiple grass cuts were taken over two-years. Results Grass Mg concentration increased with increasing Mg-fertiliser application rates in all cultivars and conditions. Under field conditions, cv. Bb2067 had 11–73% greater grass Mg concentration and smaller forage tetany index (FTI) than other cultivars across the Mg-fertiliser application rates, sites and cuts. Grass dry matter (DM) yield of cv. Bb2067 was significantly ( p < 0.05) smaller than cv. Alamo. The effect of Mg-fertiliser rate on DM yield was not significant ( p ≥ 0.05). Conclusions Biofortification of grass with Mg through breeding and agronomy can improve the forage Mg concentration for grazing ruminants, even in high-growth spring grass conditions when hypomagnesaemia is most prevalent. Response to agronomic biofortification varied with cultivar, Mg-fertiliser rate, site and weather. The cost:benefit of these approaches and farmer acceptability, and the impact on cattle and sheep grazing on grasses biofortified with Mg requires further investigation.

Unraveling neuroHIV in the Presence of Substance Use Disorders - Yu Lin; Johnny J. He; Roger Sorensen; Linda Chang (Journal of Neuroimmune Pharmacology, 2020)

Melatonin ameliorates spatial memory and motor deficits via preserving the integrity of cortical and hippocampal dendritic spine morphology in mice with neurotrauma - Xiao-Jing Lin; Ruoxu Liu; Chenyi Li; Xueqing Yi; Bo Fu; M. J. Walker; Xiao-Ming Xu; Gang Sun; Cheng-Hsien Lin (Inflammopharmacology, 2020)

Dietary exposure assessment of cadmium, arsenic, and lead in market rice from Sri Lanka - Lin Liu; Jialiang Han; Xiaohang Xu; Zhidong Xu; Kasun S. Abeysinghe; Anjana J. Atapattu; P. Mangala C. S. De Silva; Qinhui Lu; Guangle Qiu (Environmental Science and Pollution Research, 2020)

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Daniela Alioto; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Simon J. Anthony; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Tomáš Bartonička; et al. (Archives of Virology, 2020)

Public Perceptions of Mangrove Forests Matter for Their Conservation - Farid Dahdouh-Guebas; Gordon N. Ajonina; A. Aldrie Amir; Dominic A. Andradi-Brown; Irfan Aziz; Thorsten Balke; Edward B. Barbier; Stefano Cannicci; Simon M. Cragg; Marília Cunha-Lignon; David J. Curnick; Carlos M. Duarte; et al. (Frontiers in Marine Science, 2020)

Suitable plant combinations for ecological floating beds in eutrophic subtropical coastal wetlands under different salinities: experimental evidences - J. C. Lyu; G. H. Lin; Z. Y. Fan; W. X. Lin; Z. Dai (International Journal of Environmental Science and Technology, 2020)

Zooplankton in a continuous waterscape: environmental and spatial factors shaping spring zooplankton community structure in a large canyon reservoir at the tropic of cancer - Eric Zeus C. Rizo; Ping Liu; Haiyu Niu; Yang Yang; Qiuqi Lin; Rey Donne S. Papa; Henri J. Dumont; Bo-Ping Han (Hydrobiologia, 2020)

New evidence for Jurassic continental rifting in the northern Sanandaj Sirjan Zone, western Iran: the Ghalaylan seamount, southwest Ghorveh - Hossein Azizi; Fatemeh Nouri; Robert J. Stern; Marie Azizi; Federico Lucci; Yoshihiro Asahara; Mohammad Hossein Zarinkoub; Sun Lin Chung (International Geology Review, 2020)

Developing a USLE cover and management factor (C) for forested regions of southern China - Conghui Li; Lili Lin; Zhenbang Hao; Christopher J. Post; Zhanghao Chen; Jian Liu; Kunyong Yu (Frontiers of Earth Science, 2020)

Climate change considerations are fundamental to management of deep‐sea resource extraction - Lisa A. Levin; Chih‐Lin Wei; Daniel C. Dunn; Diva J. Amon; Oliver S. Ashford; William W. L. Cheung; Ana Colaço; Carlos Dominguez‐Carrió; Elva G. Escobar; Harriet R. Harden‐Davies; Jeffrey C. Drazen; Khaira Ismail; et al. (Global Change Biology, 2020)
Climate change manifestation in the ocean, through warming, oxygen loss, increasing acidification, and changing particulate organic carbon flux (one metric of altered food supply), is projected to affect most deep‐ocean ecosystems concomitantly with increasing direct human disturbance. Climate drivers will alter deep‐sea biodiversity and associated ecosystem services, and may interact with disturbance from resource extraction activities or even climate geoengineering. We suggest that to ensure the effective management of increasing use of the deep ocean (e.g., for bottom fishing, oil and gas extraction, and deep‐seabed mining), environmental management and developing regulations must consider climate change. Strategic planning, impact assessment and monitoring, spatial management, application of the precautionary approach, and full‐cost accounting of extraction activities should embrace climate consciousness. Coupled climate and biological modeling approaches applied in the water and on the seafloor can help accomplish this goal. For example, Earth‐System Model projections of climate‐change parameters at the seafloor reveal heterogeneity in projected climate hazard and time of emergence (beyond natural variability) in regions targeted for deep‐seabed mining. Models that combine climate‐induced changes in ocean circulation with particle tracking predict altered transport of early life stages (larvae) under climate change. Habitat suitability models can help assess the consequences of altered larval dispersal, predict climate refugia, and identify vulnerable regions for multiple species under climate change. Engaging the deep observing community can support the necessary data provisioning to mainstream climate into the development of environmental management plans. To illustrate this approach, we focus on deep‐seabed mining and the International Seabed Authority, whose mandates include regulation of all mineral‐related activities in international waters and protecting the marine environment from the harmful effects of mining. However, achieving deep‐ocean sustainability under the UN Sustainable Development Goals will require integration of climate consideration across all policy sectors.

A System Level Analysis of Coastal Ecosystem Responses to Hurricane Impacts - C. J. Patrick; L. Yeager; A. R. Armitage; F. Carvallo; V. M. Congdon; K. H. Dunton; M. Fisher; A. K. Hardison; J. D. Hogan; J. Hosen; X. Hu; B. Kiel Reese; et al. (Estuaries and Coasts, 2020)

Emergence of a hybrid PKS‐NRPS secondary metabolite cluster in a clonal population of the rice blast fungus Magnaporthe oryzae - Zhenhui Zhong; Lianyu Lin; Huakun Zheng; Jiandong Bao; Meilian Chen; Limei Zhang; Wei Tang; Daniel J. Ebbole; Zonghua Wang (Environmental Microbiology, 2020)
Summary Secondary metabolites (SMs) are crucial for fungi and vary in function from beneficial antibiotics to pathogenicity factors. To generate diversified SMs that enable different functions, SM‐coding regions rapidly evolve in fungal genomes. However, the driving force and genetic mechanism of fungal SM diversification in the context of host‐pathogen interactions remain largely unknown. Previously, we grouped field populations of the rice blast fungus Magnaporthe oryzae (syn: Pyricularia oryzae ) into three major globally distributed clades based on population genomic analyses. Here, we characterize a recent duplication of an avirulent gene‐containing SM cluster, ACE1, in a clonal M . oryzae population (Clade 2). We demonstrate that the ACE1 cluster is specifically duplicated in Clade 2, a dominant clade in indica rice‐growing areas. With long‐read sequencing, we obtained chromosome‐level genome sequences of four Clade 2 isolates, which displayed differences in genomic organization of the ACE1 duplication process. Comparative genomic analyses suggested that the original ACE1 cluster experienced frequent rearrangement in Clade 2 isolates and revealed that the new ACE1 cluster is located in a newly formed and transposable element‐rich region. Taken together, these results highlight the frequent mutation and expansion of an avirulent gene‐containing SM cluster through transposable element‐mediated whole‐cluster duplication in the context of host‐pathogen interactions.

A Major Hydrothermal Reservoir Underneath the Tatun Volcano Group of Taiwan: Clues from a Dense Linear Geophone Array - C. H. Lin; Y. C. Lai; M. H. Shih; C. J. Lin; J. S. Ku; Y. C. Huang (Pure and Applied Geophysics, 2020)
A dense linear geophone array is deployed across the Tatun volcano group (TVG) at the northern tip of Taiwan, where more than 7 million residents live in the Taipei metropolis. The array is composed of 50 geophones with a station spacing of ~ 200 m in average, and it is designed for striking in the NW–SE direction to record the many earthquakes in eastern Taiwan, where the Philippine Sea plate subducted beneath the Eurasia plate. The detailed examination of felt earthquakes shows consistent P-wave delays are recorded at particular stations of the array. The further forward modeling indicates there is a low-velocity zone (LVZ) at depths between ~ 0.5 and ~ 2.5 km beneath the major fumarole sites. Combining this preliminary result with previous studies including clustering seismicity, volcanic earthquakes, low-resistivity zone, strong degassing processes and shallow velocity structures, we suggest that the LVZ might be associated with the major hydrothermal reservoir at the TVG. The identification of the hydrothermal reservoir by the LVZ not only implies a potential volcanic threat, such as phreatic eruptions, in the future, but also provides the possibility of sustainable geothermal resources for replacing traditional nuclear and fossil fuel power plants. Detailed images of the LVZ and other volcanic structures will be obtained soon when dense geophone arrays with more than 600 geophones are deployed from 2020 to 2022.

Developing quantitative PCR assays to detect threatened and invasive freshwater turtles in Hong Kong using environmental DNA - Ivan P. Y. Lam; Yik-Hei Sung; Liu Lin; Jonathan J. Fong (Conservation Genetics Resources, 2020)

Alternative designs and tropical tree seedling growth performance landscapes - Samantha J. Worthy; Daniel C. Laughlin; Jenny Zambrano; María N. Umaña; Caicai Zhang; Luxiang Lin; Min Cao; Nathan G. Swenson (Ecology, 2020)
The functional trait values that constitute a whole‐plant phenotype interact with the environment to determine demographic rates. Current approaches often fail to explicitly consider trait × trait and trait × environment interactions, which may lead to missed information that is valuable for understanding and predicting the drivers of demographic rates and functional diversity. Here, we consider these interactions by modeling growth performance landscapes that span multidimensional trait spaces along environmental gradients. We utilize individual‐level leaf, stem, and root trait data combined with growth data from tree seedlings along soil nutrient and light gradients in a hyper‐diverse tropical rainforest. We find that multiple trait combinations in phenotypic space (i.e., alternative designs) lead to multiple growth performance peaks that shift along light and soil axes such that no single or set of interacting traits consistently results in peak growth performance. Evidence from these growth performance peaks also generally indicates frequent independence of above‐ and belowground resource acquisition strategies. These results help explain how functional diversity is maintained in ecological communities and question the practice of utilizing a single trait or environmental variable, in isolation, to predict the growth performance of individual trees.

Assessment of ammonium fertilization as a stimulus for proline accumulation in Oryza sativa L. during cyanide assimilation - W. Liu; X.-Z. Yu; S.-Y. Lei; L. Yang; Y.-J. Lin (International Journal of Environmental Science and Technology, 2020)

Geochemistry of continental alkali basalts in the Sabzevar region, northern Iran: implications for the role of pyroxenite in magma genesis - Mojtaba Rostami-Hossouri; Habibollah Ghasemi; Kwan-Nang Pang; J. Gregory Shellnutt; Mehdi Rezaei-Kahkhaei; Laicheng Miao; Mohsen Mobasheri; Yoshiyuki Iizuka; Hao-Yang Lee; Te-Hsien Lin (Contributions to Mineralogy and Petrology, 2020)

Gut microbial diversity across a contact zone for California voles: Implications for lineage divergence of hosts and mitonuclear mismatch in the assembly of the mammalian gut microbiome - Dana Lin; Eileen A. Lacey; Bryan H. Bach; Ke Bi; Christopher J. Conroy; Anton Suvorov; Rauri C. K. Bowie (Molecular Ecology, 2020)
Gut microbial diversity is thought to reflect the co‐evolution of microbes and their hosts as well as current host‐specific attributes such as genetic background and environmental setting. To explore interactions among these parameters, we characterized variation in gut microbiome composition of California voles ( Microtus californicus ) across a contact zone between two recently diverged lineages of this species. Because this contact zone contains individuals with mismatched mitochondrial‐nuclear genomes (cybrids), it provides an important opportunity to explore how different components of the genotype contribute to gut microbial diversity. Analyses of bacterial 16S rRNA sequences and joint species distribution modelling revealed that host genotypes and genetic differentiation among host populations together explained more than 50% of microbial community variation across our sampling transect. The ranked importance (most to least) of factors contributing to gut microbial diversity in our study populations were: genome‐wide population differentiation, local environmental conditions, and host genotypes. However, differences in microbial communities among vole populations (β‐diversity) did not follow patterns of lineage divergence (i.e., phylosymbiosis). Instead, among‐population variation was best explained by the spatial distribution of hosts, as expected if the environment is a primary source of gut microbial diversity (i.e., dispersal limitation hypothesis). Across the contact zone, several bacterial taxa differed in relative abundance between the two parental lineages as well as among individuals with mismatched mitochondrial and nuclear genomes. Thus, genetic divergence among host lineages and mitonuclear genomic mismatches may also contribute to microbial diversity by altering interactions between host genomes and gut microbiota (i.e., hologenome speciation hypothesis).

Sedimentary environment and facies of the Huagang Formation in the northern central Xihu Depression, East China Sea Basin, China - Z. X. Zhao; C. M. Dong; C. Y. Lin; X. G. Zhang; X. Huang; B. J. Li; W. Guo; Z. Q. Zhu (Australian Journal of Earth Sciences, 2020)

Climate‐induced changes in the suitable habitat of cold‐water corals and commercially important deep‐sea fishes in the North Atlantic - Telmo Morato; José‐Manuel González‐Irusta; Carlos Dominguez‐Carrió; Chih‐Lin Wei; Andrew Davies; Andrew K. Sweetman; Gerald H. Taranto; Lindsay Beazley; Ana García‐Alegre; Anthony Grehan; Pascal Laffargue; Francisco Javier Murillo; et al. (Global Change Biology, 2020)
The deep sea plays a critical role in global climate regulation through uptake and storage of heat and carbon dioxide. However, this regulating service causes warming, acidification and deoxygenation of deep waters, leading to decreased food availability at the seafloor. These changes and their projections are likely to affect productivity, biodiversity and distributions of deep‐sea fauna, thereby compromising key ecosystem services. Understanding how climate change can lead to shifts in deep‐sea species distributions is critically important in developing management measures. We used environmental niche modelling along with the best available species occurrence data and environmental parameters to model habitat suitability for key cold‐water coral and commercially important deep‐sea fish species under present‐day (1951–2000) environmental conditions and to project changes under severe, high emissions future (2081–2100) climate projections (RCP8.5 scenario) for the North Atlantic Ocean. Our models projected a decrease of 28%–100% in suitable habitat for cold‐water corals and a shift in suitable habitat for deep‐sea fishes of 2.0°–9.9° towards higher latitudes. The largest reductions in suitable habitat were projected for the scleractinian coral Lophelia pertusa and the octocoral Paragorgia arborea , with declines of at least 79% and 99% respectively. We projected the expansion of suitable habitat by 2100 only for the fishes Helicolenus dactylopterus and Sebastes mentella (20%–30%), mostly through northern latitudinal range expansion. Our results projected limited climate refugia locations in the North Atlantic by 2100 for scleractinian corals (30%–42% of present‐day suitable habitat), even smaller refugia locations for the octocorals Acanella arbuscula and Acanthogorgia armata (6%–14%), and almost no refugia for P. arborea . Our results emphasize the need to understand how anticipated climate change will affect the distribution of deep‐sea species including commercially important fishes and foundation species, and highlight the importance of identifying and preserving climate refugia for a range of area‐based planning and management tools.

Alpine grassland plants grow earlier and faster but biomass remains unchanged over 35 years of climate change - Hao Wang; Huiying Liu; Guangmin Cao; Zhiyuan Ma; Yikang Li; Fawei Zhang; Xia Zhao; Xinquan Zhao; Lin Jiang; Nathan J. Sanders; Aimée T. Classen; Jin‐Sheng He (Ecology Letters, 2020)
Satellite data indicate significant advancement in alpine spring phenology over decades of climate warming, but corresponding field evidence is scarce. It is also unknown whether this advancement results from an earlier shift of phenological events, or enhancement of plant growth under unchanged phenological pattern. By analyzing a 35‐year dataset of seasonal biomass dynamics of a Tibetan alpine grassland, we show that climate change promoted both earlier phenology and faster growth, without changing annual biomass production. Biomass production increased in spring due to a warming‐induced earlier onset of plant growth, but decreased in autumn due mainly to increased water stress. Plants grew faster but the fast‐growing period shortened during the mid‐growing season. These findings provide the first in situ evidence of long‐term changes in growth patterns in alpine grassland plant communities, and suggest that earlier phenology and faster growth will jointly contribute to plant growth in a warming climate.

Cytotoxic components from the Xisha sponge Fascaplysinopsis reticulata - Guo-Fei Qin; Xu-Li Tang; Nicole J. de Voogd; Ping-Lin Li; Guo-Qiang Li (Natural Product Research, 2020)

Population Structure of the World Vegetable Center Mungbean Mini Core Collection and Genome-Wide Association Mapping of Loci Associated with Variation of Seed Coat Luster - Caleb Manamik Breria; Ching Hsiang Hsieh; Jo-Yi Yen; Ramakrishnan Nair; Chen-Yu Lin; Shu-Mei Huang; Thomas J. Noble; Roland Schafleitner (Tropical Plant Biology, 2020)

Interspecific interactions in dual-species biofilms of soil bacteria: effects of fertilization practices - Xiaojie Sun; Peng Cai; Søren J. Sørensen; Monika Mortimer; Chunhui Gao; Qiaoyun Huang; Yiming Wang; Xiangui Lin; Yichao Wu; Di Zhu; Ruirui Chen (Journal of Soils and Sediments, 2020)

New insights into antimetastatic signaling pathways of melatonin in skeletomuscular sarcoma of childhood and adolescence - Ko-Hsiu Lu; Chiao-Wen Lin; Yi-Hsien Hsieh; Shih-Chi Su; Russel J. Reiter; Shun-Fa Yang (Cancer and Metastasis Reviews, 2020)

A new slice-based method for calculating the minimum safe thickness for a filled-type karst cave - Z. H. Xu; X. Huang; S. C. Li; P. Lin; X. S. Shi; J. Wu (Bulletin of Engineering Geology and the Environment, 2020)

The Potential of Constructed Wetland Plants for Bioethanol Production - Yan Lin; Yafang Zhao; Xinyi Ruan; Tyler J. Barzee; Zhenyu Zhang; Hainan Kong; Xiaoling Zhang (BioEnergy Research, 2020)

Potential changes to the biology and challenges to the management of invasive sea lamprey Petromyzon marinus in the Laurentian Great Lakes due to climate change - Robert J. Lennox; Gale A. Bravener; Hsien‐Yung Lin; Charles P. Madenjian; Andrew M. Muir; Christina K. Remucal; Kelly F. Robinson; Andrew M. Rous; Michael J. Siefkes; Michael P. Wilkie; Daniel P. Zielinski; Steven J. Cooke (Global Change Biology, 2020)
Control programs are implemented to mitigate the damage caused by invasive species worldwide. In the highly invaded Great Lakes, the climate is expected to become warmer with more extreme weather and variable precipitation, resulting in shorter iced‐over periods and variable tributary flows as well as changes to pH and river hydrology and hydrogeomorphology. We review how climate change influences physiology, behavior, and demography of a damaging invasive species, sea lamprey ( Petromyzon marinus ), in the Great Lakes, and the consequences for sea lamprey control efforts. Sea lamprey control relies on surveys to monitor abundance of larval sea lamprey in Great Lakes tributaries. The abundance of parasitic, juvenile sea lampreys in the lakes is calculated by surveying wounding rates on lake trout ( Salvelinus namaycush ), and trap surveys are used to enumerate adult spawning runs. Chemical control using lampricides (i.e., lamprey pesticides) to target larval sea lamprey and barriers to prevent adult lamprey from reaching spawning grounds are the most important tools used for sea lamprey population control. We describe how climate change could affect larval survival in rivers, growth and maturation in lakes, phenology and the spawning migration as adults return to rivers, and the overall abundance and distribution of sea lamprey in the Great Lakes. Our review suggests that Great Lakes sea lamprey may benefit from climate change with longer growing seasons, more rapid growth, and greater access to spawning habitat, but uncertainties remain about the future availability and suitability of larval habitats. Consideration of the biology of invasive species and adaptation of the timing, intensity, and frequency of control efforts is critical to the management of biological invasions in a changing world, such as sea lamprey in the Great Lakes.

Experimental and Analytical Investigations of the Effect of Hole Size on Borehole Breakout Geometries for Estimation of In Situ Stresses - H. Lin; J. Oh; I. Canbulat; T. R. Stacey (Rock Mechanics and Rock Engineering, 2020)

Managing water quality in a river basin with uncertainty - H.-W. Chen; W.-Y. Chen; C.-T. Wang; Y.-H. Lin; M.-J. Deng; C.-Y. Chiang (International Journal of Environmental Science and Technology, 2020)

Seasonal Disconnect Between Streamflow and Retention Shapes Riverine Nitrogen Export in the Willamette River Basin, Oregon - Jana E. Compton; Kara E. Goodwin; Daniel J. Sobota; Jiajia Lin (Ecosystems, 2020)

TRY plant trait database – enhanced coverage and open access - Jens Kattge; Gerhard Bönisch; Sandra Díaz; Sandra Lavorel; Iain Colin Prentice; Paul Leadley; Susanne Tautenhahn; Gijsbert D. A. Werner; Tuomas Aakala; Mehdi Abedi; Alicia T. R. Acosta; George C. Adamidis; et al. (Global Change Biology, 2020)
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits—almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.

Temporal population variability in local forest communities has mixed effects on tree species richness across a latitudinal gradient - Tak Fung; Ryan A. Chisholm; Kristina Anderson‐Teixeira; Norm Bourg; Warren Y. Brockelman; Sarayudh Bunyavejchewin; Chia‐Hao Chang‐Yang; Rutuja Chitra‐Tarak; George Chuyong; Richard Condit; Handanakere S. Dattaraja; Stuart J. Davies; et al. (Ecology Letters, 2020)
Among the local processes that determine species diversity in ecological communities, fluctuation‐dependent mechanisms that are mediated by temporal variability in the abundances of species populations have received significant attention. Higher temporal variability in the abundances of species populations can increase the strength of temporal niche partitioning but can also increase the risk of species extinctions, such that the net effect on species coexistence is not clear. We quantified this temporal population variability for tree species in 21 large forest plots and found much greater variability for higher latitude plots with fewer tree species. A fitted mechanistic model showed that among the forest plots, the net effect of temporal population variability on tree species coexistence was usually negative, but sometimes positive or negligible. Therefore, our results suggest that temporal variability in the abundances of species populations has no clear negative or positive contribution to the latitudinal gradient in tree species richness.

Expanding Tara Oceans Protocols for Underway, Ecosystemic Sampling of the Ocean-Atmosphere Interface During Tara Pacific Expedition (2016–2018) - Gabriel Gorsky; Guillaume Bourdin; Fabien Lombard; Maria Luiza Pedrotti; Samuel Audrain; Nicolas Bin; Emmanuel Boss; Chris Bowler; Nicolas Cassar; Loic Caudan; Genevieve Chabot; Natalie R. Cohen; et al. (Frontiers in Marine Science, 2019)

Castor patatin-like phospholipase A IIIβ facilitates removal of hydroxy fatty acids from phosphatidylcholine in transgenic Arabidopsis seeds - Yingyu Lin; Guanqun Chen; Elzbieta Mietkiewska; Ziliang Song; Kristian Mark P. Caldo; Stacy D. Singer; John Dyer; Mark Smith; Thomas McKeon; Randall J. Weselake (Plant Molecular Biology, 2019)

Inflammation-related genes are associated with epigenetic aging in HIV - Erin E. Sundermann; Mariam A. Hussain; David J. Moore; Steven Horvath; David T. S. Lin; Michael S. Kobor; Andrew Levine (Journal of NeuroVirology, 2019)

Climate warming alters subsoil but not topsoil carbon dynamics in alpine grassland - Juan Jia; Zhenjiao Cao; Chengzhu Liu; Zhenhua Zhang; Li Lin; Yiyun Wang; Negar Haghipour; Lukas Wacker; Hongyan Bao; Thorston Dittmar; Myrna J. Simpson; Huan Yang; et al. (Global Change Biology, 2019)
Subsoil contains more than half of soil organic carbon (SOC) globally and is conventionally assumed to be relatively unresponsive to warming compared to the topsoil. Here, we show substantial changes in carbon allocation and dynamics of the subsoil but not topsoil in the Qinghai‐Tibetan alpine grasslands over 5 years of warming. Specifically, warming enhanced the accumulation of newly synthesized ( 14 C‐enriched) carbon in the subsoil slow‐cycling pool (silt‐clay fraction) but promoted the decomposition of plant‐derived lignin in the fast‐cycling pool (macroaggregates). These changes mirrored an accumulation of lipids and sugars at the expense of lignin in the warmed bulk subsoil, likely associated with shortened soil freezing period and a deepening root system. As warming is accompanied by deepening roots in a wide range of ecosystems, root‐driven accrual of slow‐cycling pool may represent an important and overlooked mechanism for a potential long‐term carbon sink at depth. Moreover, given the contrasting sensitivity of SOC dynamics at varied depths, warming studies focusing only on surface soils may vastly misrepresent shifts in ecosystem carbon storage under climate change.

Adapting to climate change: an assessment of local adaptation planning processes in forest-based communities in Nepal - Pratigya Silwal; Lin Roberts; Hamish G. Rennie; Manfred J. Lexer (Climate and Development, 2019)

Characteristics and distribution of clay minerals and their effects on reservoir quality: Huagang Formation in the Xihu Sag, East China Sea Basin - X. L. Sun; C. Y. Lin; X. G. Zhang; J. L. Lin; Z. X. Zhao; D. W. Huang; D. P. Duan (Australian Journal of Earth Sciences, 2019)

Indication of dynamic neurovascular coupling from inconsistency between EEG and fMRI indices across sleep–wake states - Changwei W. Wu; Pei-Jung Tsai; Sharon Chia-Ju Chen; Chia-Wei Li; Ai-Ling Hsu; Hong-Yi Wu; Yu-Ting Ko; Pai-Chuan Hung; Chun-Yen Chang; Ching-Po Lin; Timothy J. Lane; Chia-Yuen Chen (Sleep and Biological Rhythms, 2019)

A direct comparison of divalent metal-ion transporter (DMT1) and hinokitiol, a potential small molecule replacement - Michael D. Garrick; Laura M. Garrick; Lin Zhao; James F. Collins; Joleen Soukup; Andrew J. Ghio (BioMetals, 2019)

Crops For the Future (CFF): an overview of research efforts in the adoption of underutilised species - Peter J. Gregory; Sean Mayes; Chai Hui Hui; Ebrahim Jahanshiri; Advina Julkifle; Giva Kuppusamy; Ho Wai Kuan; Tan Xin Lin; Festo Massawe; T. A. S. T. M. Suhairi; Sayed N. Azam-Ali (Planta, 2019)

Long term experimental drought alters community plant trait variation, not trait means, across three semiarid grasslands - Wentao Luo; Xiaoan Zuo; Robert J. Griffin-Nolan; Chong Xu; Wang Ma; Lin Song; Kenny Helsen; Yingchao Lin; Jiangping Cai; Qiang Yu; Zhengwen Wang; Melinda D. Smith; et al. (Plant and Soil, 2019)

3,000 km and 1,500‐year presence of Aureococcus anophagefferens reveals indigenous origin of brown tides in China - Ying Zhong Tang; Zhaopeng Ma; Zhangxi Hu; Yunyan Deng; Aoao Yang; Siheng Lin; Liang Yi; Zhaoyang Chai; Christopher J. Gobler (Molecular Ecology, 2019)
The nonmotile, spherical, picoplanktonic (2‐μm‐sized) pelagophyte Aureococcus anophagefferens has caused numerous harmful blooms (“brown tides”) across global marine ecosystems. Blooms have developed along the east coast of the USA since 1985, a limited number of times in South Africa around 1997, and frequently in China since 2009. As a consequence, the harmful blooms have caused massive losses in aquaculture and coastal ecosystems, particularly mortalities in cultured shellfish. Therefore, whether A. anophagefferens was recently introduced to China via natural/artificial transport of resting stage cells or has been an indigenous species has become a question of profound ecological significance and broad interest, which motivated our extensive investigation on the geographic and historical presence of this species in the seas of China. We applied a combined approach of extensive PCR‐based detection and sequencing, germination experiments and monoclonal antibody staining of germlings to samples of surface sediment and sediment core (dated via combined isotopic measurements) collected from all four seas of China, and searched the supplementary data set of a recent Science publication. We discovered that A. anophagefferens does have a resting stage in the sediment, but it also has a wide geographic distribution both in China (covering a range of ~30° in latitude, ~15.7° in longitude and 2.5–3,456 m in water depth; temperate to tropical and coastal to open oceans) and in almost all oceans of the world and a historical presence of >1,500 years in the Bohai Sea, China. The work revealed that A. anophagefferens is not a recently introduced, but an indigenous species in China and has in fact a globally cosmopolitan distribution.

Global in situ Observations of Essential Climate and Ocean Variables at the Air–Sea Interface - Luca R. Centurioni; Jon Turton; Rick Lumpkin; Lancelot Braasch; Gary Brassington; Yi Chao; Etienne Charpentier; Zhaohui Chen; Gary Corlett; Kathleen Dohan; Craig Donlon; Champika Gallage; et al. (Frontiers in Marine Science, 2019)

Global Perspectives on Observing Ocean Boundary Current Systems - Robert E. Todd; Francisco P. Chavez; Sophie Clayton; Sophie Cravatte; Marlos Goes; Michelle Graco; Xiaopei Lin; Janet Sprintall; Nathalie V. Zilberman; Matthew Archer; Javier Arístegui; Magdalena Balmaseda; et al. (Frontiers in Marine Science, 2019)

A breeding strategy targeting the secondary gene pool of bread wheat: introgression from a synthetic hexaploid wheat - Ming Hao; Lianquan Zhang; Laibin Zhao; Shoufen Dai; Aili Li; Wuyun Yang; Die Xie; Qingcheng Li; Shunzong Ning; Zehong Yan; Bihua Wu; Xiujin Lan; et al. (Theoretical and Applied Genetics, 2019)

Production and characterization of lipopeptide biosurfactant producing Paenibacillus sp. D9 and its biodegradation of diesel fuel - A. A. Jimoh; J. Lin (International Journal of Environmental Science and Technology, 2019)

Ocean Climate Observing Requirements in Support of Climate Research and Climate Information - Detlef Stammer; Annalisa Bracco; Krishna AchutaRao; Lisa Beal; Nathaniel L. Bindoff; Pascale Braconnot; Wenju Cai; Dake Chen; Matthew Collins; Gokhan Danabasoglu; Boris Dewitte; Riccardo Farneti; et al. (Frontiers in Marine Science, 2019)

Comparison of PM2.5 emission rates and source profiles for traditional Chinese cooking styles - Pengchuan Lin; Wanqing He; Lei Nie; James J. Schauer; Yuqin Wang; Shujian Yang; Yuanxun Zhang (Environmental Science and Pollution Research, 2019)

Taxonomy of the order Mononegavirales: update 2019 - Gaya K. Amarasinghe; María A. Ayllón; Yīmíng Bào; Christopher F. Basler; Sina Bavari; Kim R. Blasdell; Thomas Briese; Paul A. Brown; Alexander Bukreyev; Anne Balkema-Buschmann; Ursula J. Buchholz; Camila Chabi-Jesus; et al. (Archives of Virology, 2019)

Host genetic determinants of the gut microbiota of wild mice - Taichi A. Suzuki; Megan Phifer‐Rixey; Katya L. Mack; Michael J. Sheehan; Dana Lin; Ke Bi; Michael W. Nachman (Molecular Ecology, 2019)
Identifying a common set of genes that mediate host–microbial interactions across populations and species of mammals has broad relevance for human health and animal biology. However, the genetic basis of the gut microbial composition in natural populations remains largely unknown outside of humans. Here, we used wild house mouse populations as a model system to ask three major questions: (a) Does host genetic relatedness explain interindividual variation in gut microbial composition? (b) Do population differences in the microbiota persist in a common environment? (c) What are the host genes associated with microbial richness and the relative abundance of bacterial genera? We found that host genetic distance is a strong predictor of the gut microbial composition as characterized by 16S amplicon sequencing. Using a common garden approach, we then identified differences in microbial composition between populations that persisted in a shared laboratory environment. Finally, we used exome sequencing to associate host genetic variants with microbial diversity and relative abundance of microbial taxa in wild mice. We identified 20 genes that were associated with microbial diversity or abundance including a macrophage‐derived cytokine ( IL12a ) that contained three nonsynonymous mutations. Surprisingly, we found a significant overrepresentation of candidate genes that were previously associated with microbial measurements in humans. The homologous genes that overlapped between wild mice and humans included genes that have been associated with traits related to host immunity and obesity in humans. Gene–bacteria associations identified in both humans and wild mice suggest some commonality to the host genetic determinants of gut microbial composition across mammals.

Limbic system structure volumes and associated neurocognitive functioning in former NFL players - Christian Lepage; Marc Muehlmann; Yorghos Tripodis; Jakob Hufschmidt; Julie Stamm; Katie Green; Pawel Wrobel; Vivian Schultz; Isabelle Weir; Michael L. Alosco; Christine M. Baugh; Nathan G. Fritts; et al. (Brain Imaging and Behavior, 2019)

Synthetic sideromycins (skepticism and optimism): selective generation of either broad or narrow spectrum Gram-negative antibiotics - Yun-Ming Lin; Manuka Ghosh; Patricia A. Miller; Ute Möllmann; Marvin J. Miller (BioMetals, 2019)

Primary Productivity Dynamics in the Summer Arctic Ocean Confirms Broad Regulation of the Electron Requirement for Carbon Fixation by Light-Phytoplankton Community Interaction - Yuanli Zhu; David J. Suggett; Chenggang Liu; Jianfeng He; Longshan Lin; Fengfeng Le; Joji Ishizaka; Joaquim Goes; Qiang Hao (Frontiers in Marine Science, 2019)

Transcription Factor 2I Regulates Neuronal Development via TRPC3 in 7q11.23 Disorder Models - Marielle H. S. Deurloo; Ekaterina Turlova; Wen-Liang Chen; You Wei Lin; Elaine Tam; Nardos G. Tassew; Michael Wu; Ya-Chi Huang; Jacqueline N. Crawley; Philippe P. Monnier; Alexander J. A. Groffen; Hong-Shuo Sun; et al. (Molecular Neurobiology, 2019)

Cr-induced disturbance on expression of six COX genes in rice seedlings - X.-Z. Yu; C.-J. Lu; Y.-J. Lin; Y.-H. Li (International Journal of Environmental Science and Technology, 2019)

The urgent need for microbiology literacy in society - Kenneth Timmis; Ricardo Cavicchioli; José Luis Garcia; Balbina Nogales; Max Chavarría; Lisa Stein; Terry J. McGenity; Nicole Webster; Brajesh K. Singh; Jo Handelsman; Victor de Lorenzo; Carla Pruzzo; et al. (Environmental Microbiology, 2019)

The role of heterogeneous environment and docetaxel gradient in the emergence of polyploid, mesenchymal and resistant prostate cancer cells - Ke-Chih Lin; Gonzalo Torga; Yusha Sun; Robert Axelrod; Kenneth J. Pienta; James C. Sturm; Robert H. Austin (Clinical & Experimental Metastasis, 2019)

Taxonomy of the order Mononegavirales: second update 2018 - Piet Maes; Gaya K. Amarasinghe; María A. Ayllón; Christopher F. Basler; Sina Bavari; Kim R. Blasdell; Thomas Briese; Paul A. Brown; Alexander Bukreyev; Anne Balkema-Buschmann; Ursula J. Buchholz; Kartik Chandran; et al. (Archives of Virology, 2019)

Dissolution Testing in Drug Product Development: Workshop Summary Report - Andreas Abend; David Curran; Jesse Kuiper; Xujin Lu; Hanlin Li; Andre Hermans; Pramod Kotwal; Dorys A. Diaz; Michael J. Cohen; Limin Zhang; Erika Stippler; German Drazer; et al. (The AAPS Journal, 2019)

A differential k-mer analysis pipeline for comparing RNA-Seq transcriptome and meta-transcriptome datasets without a reference - Chon-Kit Kenneth Chan; Nedeljka Rosic; Michał T. Lorenc; Paul Visendi; Meng Lin; Paulina Kaniewska; Brett J. Ferguson; Peter M. Gresshoff; Jacqueline Batley; David Edwards (Functional & Integrative Genomics, 2019)

Exposure of consumers and farmers to organophosphate and synthetic pyrethroid insecticides in Northern Thailand - Surat Hongsibsong; Tippawan Prapamontol; Jie-Xian Dong; Candace S. Bever; Zhen-Lin Xu; Shirley J. Gee; Bruce D. Hammock (Journal of Consumer Protection and Food Safety, 2019)

Identify a shared neural circuit linking multiple neuropsychiatric symptoms with Alzheimer’s pathology - Xixi Wang; Ping Ren; Mark Mapstone; Yeates Conwell; Anton P. Porsteinsson; John J. Foxe; Rajeev D. S. Raizada; Feng Lin (Brain Imaging and Behavior, 2019)

Understanding the evolving phenotype of vascular complications in telomere biology disorders - Cecilia Higgs; Yanick J. Crow; Denise M. Adams; Emmanuel Chang; Don Hayes; Utz Herbig; James N. Huang; Ryan Himes; Kunal Jajoo; F. Brad Johnson; Susan D. Reynolds; Yoshihiro Yonekawa; et al. (Angiogenesis, 2019)

Responses of legumes and grasses to non-, moderate, and dense shade in Missouri, USA. I. Forage yield and its species-level plasticity - Kejia Pang; J. W. Van Sambeek; Nadia E. Navarrete-Tindall; Chung-Ho Lin; Shibu Jose; H. E. Garrett (Agroforestry Systems, 2019)

Responses of legumes and grasses to non-, moderate, and dense shade in Missouri, USA. II. Forage quality and its species-level plasticity - Kejia Pang; J. W. Van Sambeek; Nadia E. Navarrete-Tindall; Chung-Ho Lin; Shibu Jose; H. E. Garrett (Agroforestry Systems, 2019)

Direct and indirect effects of climate on richness drive the latitudinal diversity gradient in forest trees - Chengjin Chu; James A. Lutz; Kamil Král; Tomáš Vrška; Xue Yin; Jonathan A. Myers; Iveren Abiem; Alfonso Alonso; Norm Bourg; David F.R.P. Burslem; Min Cao; Hazel Chapman; et al. (Ecology Letters, 2019)
Climate is widely recognised as an important determinant of the latitudinal diversity gradient. However, most existing studies make no distinction between direct and indirect effects of climate, which substantially hinders our understanding of how climate constrains biodiversity globally. Using data from 35 large forest plots, we test hypothesised relationships amongst climate, topography, forest structural attributes (stem abundance, tree size variation and stand basal area) and tree species richness to better understand drivers of latitudinal tree diversity patterns. Climate influences tree richness both directly, with more species in warm, moist, aseasonal climates and indirectly, with more species at higher stem abundance. These results imply direct limitation of species diversity by climatic stress and more rapid (co‐)evolution and narrower niche partitioning in warm climates. They also support the idea that increased numbers of individuals associated with high primary productivity are partitioned to support a greater number of species.

What Promotes the Recovery of Salt Marsh Infauna After Oil Spills? - J. W. Fleeger; M. R. Riggio; I. A. Mendelssohn; Q. Lin; D. R. Deis; D. S. Johnson; K. R. Carman; S. A. Graham; S. Zengel; A. Hou (Estuaries and Coasts, 2019)

DNA barcoding of traded shark fins, meat and mobulid gill plates in Singapore uncovers numerous threatened species - Benjamin J. Wainwright; Yin Cheong Aden Ip; Mei Lin Neo; Jia Jin Marc Chang; Chester Zhikai Gan; Naomi Clark-Shen; Danwei Huang; Madhu Rao (Conservation Genetics, 2018)

NTF3 Is a Novel Target Gene of the Transcription Factor POU3F2 and Is Required for Neuronal Differentiation - Yi-Mei J. Lin; I-Lun Hsin; H. Sunny Sun; Shankung Lin; Yen-Ling Lai; Hsuan-Ying Chen; Ting-Yu Chen; Ya-Ping Chen; Yi-Ting Shen; Hung-Ming Wu (Molecular Neurobiology, 2018)

Physicochemical and In Vitro Evaluation of Drug Delivery of an Antibacterial Synthetic Benzophenone in Biodegradable PLGA Nanoparticles - Gabriella Costabile; Kathrin I. Gasteyer; Venkatereddy Nadithe; Katherine Van Denburgh; Qian Lin; Shiv Sharma; Joshua J. Reineke; Steven M. Firestine; Olivia M. Merkel (AAPS PharmSciTech, 2018)

Cover Image - X Luo; G Liao; C Liu; X Jiang; M Lin; C Zhao; J Tao; Z Huang (Journal of Fish Diseases, 2018)

Characterization of bacteriophage HN 48 and its protective effects in Nile tilapia Oreochromis niloticus against Streptococcus agalactiae infections - X Luo; G Liao; C Liu; X Jiang; M Lin; C Zhao; J Tao; Z Huang (Journal of Fish Diseases, 2018)
Streptococcus agalactiae is a causative agent responsible for massive mortalities of tilapia that has led to catastrophic losses to tilapia culture globally. Bacteriophages represent a new class of antimicrobials against bacteria. In this study, we characterized the bacteriophage HN 48, which formed small and round‐transparent plaques on a double‐layer plate. With a hexagonal head and a long tail, this phage may belong to the Caudovirales according to the International Committee on Taxonomy of Viruses. HN 48 was found to have a relatively wide and highly specific host range, to be sensitive to high temperature (60–80°C) and low pH (3–5), and to be relatively stable at alkaline pH (8–10). Intraperitoneal injection with HN 48 had no adverse effects on tilapia and effectively inactivated the bacteria in the kidney. Fish that received phage therapy had 60% ± 3.3% survival rates and a delayed mean death time of about 3 days when compared to the control group. To the best of knowledge, this is the first study of tilapia streptococcal phage. Overall, the results indicated that phage HN 48 could prevent tilapia from experimental S. agalactiae infection, suggesting it has the potential to control this disease.

Patterns and drivers of species diversity in the Indo‐Pacific red seaweed Portieria - Frederik Leliaert; Dioli Ann Payo; Carlos Frederico D. Gurgel; Tom Schils; Stefano G. A. Draisma; Gary W. Saunders; Mitsunobu Kamiya; Alison R. Sherwood; Showe‐Mei Lin; John M. Huisman; Line Le Gall; Robert J. Anderson; et al. (Journal of Biogeography, 2018)
Aim Biogeographical processes underlying Indo‐Pacific biodiversity patterns have been relatively well studied in marine shallow water invertebrates and fishes, but have been explored much less extensively in seaweeds, despite these organisms often displaying markedly different patterns. Using the marine red alga Portieria as a model, we aim to gain understanding of the evolutionary processes generating seaweed biogeographical patterns. Our results will be evaluated and compared with known patterns and processes in animals. Location Indo‐Pacific marine region. Methods Species diversity estimates were inferred using DNA ‐based species delimitation methods. Historical biogeographical patterns were inferred based on a six‐gene time‐calibrated phylogeny, distribution data of 802 specimens, and probabilistic modelling of geographical range evolution. The importance of geographical isolation for speciation was further evaluated by population genetic analyses at the intraspecific level. Results We delimited 92 candidate species, most with restricted distributions, suggesting low dispersal capacity. Highest species diversity was found in the Indo‐Malay Archipelago ( IMA ). Our phylogeny indicates that Portieria originated during the late Cretaceous in the area that is now the Central Indo‐Pacific. The biogeographical history of Portieria includes repeated dispersal events to peripheral regions, followed by long‐term persistence and diversification of lineages within those regions, and limited dispersal back to the IMA . Main conclusions Our results suggest that the long geological history of the IMA played an important role in shaping Portieria diversity. High species richness in the IMA resulted from a combination of speciation at small spatial scales, possibly as a result of increased regional habitat diversity from the Eocene onwards, and species accumulation via dispersal and/or island integration through tectonic movement. Our results are consistent with the biodiversity feedback model, in which biodiversity hotspots act as both “centres of origin” and “centres of accumulation,” and corroborate previous findings for invertebrates and fish that there is no single unifying model explaining the biological diversity within the IMA .

Simulating Effects of Variable Stoichiometry and Temperature on Mixotrophy in the Harmful Dinoflagellate Karlodinium veneficum - Chih-Hsien Lin; Kevin J. Flynn; Aditee Mitra; Patricia M. Glibert (Frontiers in Marine Science, 2018)

Before and after: craving, mood, and background stress in the hours surrounding drug use and stressful events in patients with opioid-use disorder - Kenzie L. Preston; William J. Kowalczyk; Karran A. Phillips; Michelle L. Jobes; Massoud Vahabzadeh; Jia-Ling Lin; Mustapha Mezghanni; David H. Epstein (Psychopharmacology, 2018)

Pharmacodynamic and Pharmacokinetic Properties of AFPep, a Novel Peptide for the Treatment of Breast Cancer - J. A. Bennett; W. Mansouri; Q. Lin; P. Feustel; T. T. Andersen (International Journal of Peptide Research and Therapeutics, 2018)

Behavioural responses of an Australian colubrid snake (Dendrelaphis punctulatus) to a novel toxic prey item (the Cane Toad Rhinella marina) - John Llewelyn; Neil C. Choyce; Benjamin L. Phillips; Jonathan K. Webb; David J. Pearson; Lin Schwarzkopf; Richard Shine (Biological Invasions, 2018)

Speciation in the mountains and dispersal by rivers: Molecular phylogeny of Eulamprus water skinks and the biogeography of Eastern Australia - Mitzy Pepper; Joanna Sumner; Ian G. Brennan; Kate Hodges; Alan R. Lemmon; Emily Moriarty Lemmon; Garry Peterson; Daniel L. Rabosky; Lin Schwarzkopf; Ian A. W. Scott; Glenn Shea; J. Scott Keogh (Journal of Biogeography, 2018)
Aim To develop a robust phylogeny for the iconic Australian water skinks ( Eulamprus ) and to explore the influence of landscape evolution of eastern Australia on phylogeographic patterns. Location Eastern and south‐eastern Australia. Methods We used Sanger methods to sequence a mitochondrial DNA (mt DNA ) locus for 386 individuals across the five Eulamprus species to elucidate phylogeographic structure. We also sequenced a second mt DNA locus and four nuclear DNA ( nDNA ) loci for a subset of individuals to help inform our sampling strategy for next‐generation sequencing. Finally, we generated an anchored hybrid enrichment ( AHE ) approach to sequence 378 loci for 25 individuals representing the major lineages identified in our Sanger dataset. These data were used to resolve the phylogenetic relationships among the species using coalescent‐based species tree inference in * BEAST and ASTRAL . Results The relationships between Eulamprus species were resolved with a high level of confidence using our AHE dataset. In addition, our extensive mt DNA sampling revealed substantial phylogeographic structure in all species, with the exception of the geographically highly restricted E . leuraensis . Ratios of patristic distances (mt DNA / nDNA ) indicate on average a 30‐fold greater distance as estimated using the mt DNA locus ND 4. Main conclusions The major divergences between lineages strongly support previously identified biogeographic barriers in eastern Australia based on studies of other taxa. These breaks appear to correlate with regions where the Great Escarpment is absent or obscure, suggesting topographic lowlands and the accompanying dry woodlands are a major barrier to dispersal for water skinks. While some river corridors, such as the Hunter Valley, were likely historically dry enough to inhibit the movement of Eulamprus populations, our data indicate that others, such as the Murray and Darling Rivers, are able to facilitate extensive gene flow through the vast arid and semi‐arid lowlands of New South Wales and South Australia. Comparing the patristic distances between the mitochondrial and AHE datasets highlights the continued value in analysing both types of data.

An Attempt to Find a Suitable Biomass for Biochar-Based Polypropylene Biocomposites - Oisik Das; Nam Kyeun Kim; Mikael S. Hedenqvist; Richard J. T. Lin; Ajit K. Sarmah; Debes Bhattacharyya (Environmental Management, 2018)

Taxonomy of the order Mononegavirales: update 2018 - Gaya K. Amarasinghe; Nidia G. Aréchiga Ceballos; Ashley C. Banyard; Christopher F. Basler; Sina Bavari; Andrew J. Bennett; Kim R. Blasdell; Thomas Briese; Alexander Bukreyev; Yíngyún Caì; Charles H. Calisher; Cristine Campos Lawson; et al. (Archives of Virology, 2018)

Transcriptional responses of the marine green alga Micromonas pusilla and an infecting prasinovirus under different phosphate conditions - Charles Bachy; Christina J. Charlesworth; Amy M. Chan; Jan F. Finke; Chee‐Hong Wong; Chia‐Lin Wei; Sebastian Sudek; Maureen L. Coleman; Curtis A. Suttle; Alexandra Z. Worden (Environmental Microbiology, 2018)
Summary Prasinophytes are widespread marine algae for which responses to nutrient limitation and viral infection are not well understood. We studied the picoprasinophyte, Micromonas pusilla , grown under phosphate‐replete (0.65 ± 0.07 d −1 ) and 10‐fold lower (low)‐phosphate (0.11 ± 0.04 d −1 ) conditions, and infected by the phycodnavirus MpV‐SP1. Expression of 17% of Micromonas genes in uninfected cells differed by >1.5‐fold ( q

Intra‐specific relatedness, spatial clustering and reduced demographic performance in tropical rainforest trees - Xiaona Shao; Calum Brown; Samantha J. Worthy; Lu Liu; Min Cao; Qiaoming Li; Luxiang Lin; Nathan G. Swenson (Ecology Letters, 2018)
Intra‐specific negative density dependence promotes species coexistence by regulating population sizes. Patterns consistent with such density dependence are frequently reported in diverse tropical tree communities. Empirical evidence demonstrating whether intra‐specific variation is related to these patterns, however, is lacking. The present study addresses this important knowledge gap by genotyping all individuals of a tropical tree in a long‐term forest dynamics plot in tropical China. We show that related individuals are often spatially clustered, but having closely related neighbours reduces the growth performance of focal trees. We infer from the evidence that dispersal limitation and negative density dependence are operating simultaneously to impact the spatial distributions of genotypes in a natural population. Furthermore, dispersal limitation decreases local intra‐specific genetic diversity and increases negative density dependence thereby promoting niche differences and species coexistence as predicted by theory.

Front Cover - James A. Lutz; Tucker J. Furniss; Daniel J. Johnson; Stuart J. Davies; David Allen; Alfonso Alonso; Kristina J. Anderson‐Teixeira; Ana Andrade; Jennifer Baltzer; Kendall M. L. Becker; Erika M. Blomdahl; Norman A. Bourg; et al. (Global Ecology and Biogeography, 2018)

Global importance of large‐diameter trees - James A. Lutz; Tucker J. Furniss; Daniel J. Johnson; Stuart J. Davies; David Allen; Alfonso Alonso; Kristina J. Anderson‐Teixeira; Ana Andrade; Jennifer Baltzer; Kendall M. L. Becker; Erika M. Blomdahl; Norman A. Bourg; et al. (Global Ecology and Biogeography, 2018)
Aim To examine the contribution of large‐diameter trees to biomass, stand structure, and species richness across forest biomes. Location Global. Time period Early 21st century. Major taxa studied Woody plants. Methods We examined the contribution of large trees to forest density, richness and biomass using a global network of 48 large (from 2 to 60 ha) forest plots representing 5,601,473 stems across 9,298 species and 210 plant families. This contribution was assessed using three metrics: the largest 1% of trees ≥ 1 cm diameter at breast height (DBH), all trees ≥ 60 cm DBH, and those rank‐ordered largest trees that cumulatively comprise 50% of forest biomass. Results Averaged across these 48 forest plots, the largest 1% of trees ≥ 1 cm DBH comprised 50% of aboveground live biomass, with hectare‐scale standard deviation of 26%. Trees ≥ 60 cm DBH comprised 41% of aboveground live tree biomass. The size of the largest trees correlated with total forest biomass ( r 2 = .62, p r 2 = .45, p r 2 = .33, p r 2 = .17, p = .002). The concentration of biomass in the largest 1% of trees declined with increasing absolute latitude ( r 2 = .46, p r 2 = .31, p r 2 = .26, p Main conclusions Because large‐diameter trees constitute roughly half of the mature forest biomass worldwide, their dynamics and sensitivities to environmental change represent potentially large controls on global forest carbon cycling. We recommend managing forests for conservation of existing large‐diameter trees or those that can soon reach large diameters as a simple way to conserve and potentially enhance ecosystem services.

DNA Barcoding for Identification of Sugarcane Borers in China - J- D Wang; W- Z Wang; Z- L Lin; A Ali; H- Y Fu; M- T Huang; S- J Gao; R Wang (Neotropical Entomology, 2018)

FGF21 Attenuates High-Fat Diet-Induced Cognitive Impairment via Metabolic Regulation and Anti-inflammation of Obese Mice - Qingzhi Wang; Jing Yuan; Zhanyang Yu; Li Lin; Yinghua Jiang; Zeyuan Cao; Pengwei Zhuang; Michael J. Whalen; Bo Song; Xiao-Jie Wang; Xiaokun Li; Eng H. Lo; et al. (Molecular Neurobiology, 2018)

Burly1 is a mouse QTL for lean body mass that maps to a 0.8-Mb region of chromosome 2 - Cailu Lin; Brad D. Fesi; Michael Marquis; Natalia P. Bosak; Anna Lysenko; Mohammed Amin Koshnevisan; Fujiko F. Duke; Maria L. Theodorides; Theodore M. Nelson; Amanda H. McDaniel; Mauricio Avigdor; Charles J. Arayata; et al. (Mammalian Genome, 2018)

Low-level concentrations of aminoglycoside antibiotics induce the aggregation of cyanobacteria - Lin-Rui Tan; Peng-Fei Xia; Raymond J. Zeng; Qian Li; Xue-Fei Sun; Shu-Guang Wang (Environmental Science and Pollution Research, 2018)

Linking muscle metabolism and functional variation to field swimming performance in bluegill sunfish (Lepomis macrochirus) - David J. Ellerby; Shauna Cyr; Angela X. Han; Mika Lin; Lloyd A. Trueblood (Journal of Comparative Physiology B, 2018)

Correction to: Functional near-infrared spectroscopy (fNIRS) brain imaging of multi-sensory integration during computerized dynamic posturography in middle-aged and older adults - Chia-Cheng Lin; Jeffrey W. Barker; Patrick J. Sparto; Joseph M. Furman; Theodore J. Huppert (Experimental Brain Research, 2018)

On the ecological significance of pollen color: a case study in American trout lily ( Erythronium americanum ) - Emily J. Austen; Shang‐Yao Lin; Jessica R. K. Forrest (Ecology, 2018)
Evolutionary ecologists seek to explain the processes that maintain variation within populations. In plants, petal color variation can affect pollinator visitation, environmental tolerance, and herbivore deterrence. Variation in sexual organs may similarly affect plant performance. Within‐population variation in pollen color, as occurs in the eastern North American spring ephemeral Erythronium americanum , provides an excellent opportunity to investigate the maintenance of variation in this trait. Although the red/yellow pollen‐color polymorphism of E. americanum is widely recognized, it has been poorly documented. Our goals were thus (1) to determine the geographic distribution of the color morphs and (2) to test the effects of pollen color on components of pollen performance. Data provided by citizen scientists indicated that populations range from monomorphic red, to polymorphic, to monomorphic yellow, but there was no detectable geographic pattern in morph distribution, suggesting morph occurrence cannot be explained by a broad‐scale ecological cline. In field experiments, we found no effect of pollen color on the probability of predation by the pollen‐feeding beetle Asclera ruficollis , on the ability of pollen to tolerate UV ‐B radiation, or on siring success (as measured by the fruit set of hand‐pollinated flowers). Pollinators, however, exhibited site‐specific pollen‐color preferences, suggesting they may act as agents of selection on this trait, and, depending on the constancy of their preferences, could contribute to the maintenance of variation. Collectively, our results eliminate some hypothesized ecological effects of pollen color in E. americanum , and identify effects of pollen color on pollinator attraction as a promising direction for future investigation.

IGF-1-Mediated Survival from Induced Death of Human Primary Cultured Retinal Pigment Epithelial Cells Is Mediated by an Akt-Dependent Signaling Pathway - Wenhua Zheng; Qian Meng; Haitao Wang; Fengxia Yan; Peter J. Little; Xinguo Deng; Shaofen Lin (Molecular Neurobiology, 2018)

Glucohexaose-induced protein phosphatase 2C regulates cell redox status of cucumber seedling - Q M Chen; Y Yu; C M Lin; N Cui; J Y Zhao; T F Song; H Y Fan (Journal of Biosciences, 2018)

The Asian–Bering–North American teleconnection: seasonality, maintenance, and climate impact on North America - Bin Yu; H. Lin; Z. W. Wu; W. J. Merryfield (Climate Dynamics, 2018)

Biofilm community structure and the associated drag penalties of a groomed fouling release ship hull coating - Kelli Z. Hunsucker; Gary J. Vora; J. Travis Hunsucker; Harrison Gardner; Dagmar H. Leary; Seongwon Kim; Baochuan Lin; Geoffrey Swain (Biofouling, 2018)

The Benefits of Reduced Anthropogenic Climate changE (BRACE): a synthesis - Brian C. O’Neill; James M. Done; Andrew Gettelman; Peter Lawrence; Flavio Lehner; Jean-Francois Lamarque; Lei Lin; Andrew J. Monaghan; Keith Oleson; Xiaolin Ren; Benjamin M. Sanderson; Claudia Tebaldi; et al. (Climatic Change, 2018)

Glycosaminoglycans from bovine eye vitreous humour and interaction with collagen type II - Yanfei Peng; Yanlei Yu; Lei Lin; Xinyue Liu; Xing Zhang; Peipei Wang; Pauline Hoffman; So Young Kim; Fuming Zhang; Robert J. Linhardt (Glycoconjugate Journal, 2018)

Glycosaminoglycans from fish swim bladder: isolation, structural characterization and bioactive potential - Yongxi Pan; Peipei Wang; Fuming Zhang; Yanlei Yu; Xing Zhang; Lei Lin; Robert J. Linhardt (Glycoconjugate Journal, 2018)

Microbial dolomite in the sabkha environment of the middle Cambrian in the Tarim Basin, NW China - X. L. You; S. Sun; C. S. Lin; J. Q. Zhu (Australian Journal of Earth Sciences, 2018)

The persistent prevalence and evolution of cross-family recombinant coronavirus GCCDC1 among a bat population: a two-year follow-up - Joseph O. Obameso; Hong Li; Hao Jia; Min Han; Shiyan Zhu; Canping Huang; Yuhui Zhao; Min Zhao; Yu Bai; Fei Yuan; Honglan Zhao; Xia Peng; et al. (Science China Life Sciences, 2017)

Molecular screening of multidrug-resistance tuberculosis by a designated public health laboratory in Taiwan - H.-C. Lin; C.-L. Perng; Y.-W. Lai; F.-G. Lin; C.-J. Chiang; H.-A. Lin; R. Jou; T.-S. Chiueh (European Journal of Clinical Microbiology & Infectious Diseases, 2017)

Fighting an uphill battle: the recovery of frogs in Australia's Wet Tropics - Donald T. McKnight; Ross A. Alford; Conrad J. Hoskin; Lin Schwarzkopf; Sasha E. Greenspan; Kyall R. Zenger; Deborah S. Bower (Ecology, 2017)

Approaches for Establishing Clinically Relevant Dissolution Specifications for Immediate Release Solid Oral Dosage Forms - Andre Hermans; Andreas M. Abend; Filippos Kesisoglou; Talia Flanagan; Michael J. Cohen; Dorys A. Diaz; Y. Mao; Limin Zhang; Gregory K. Webster; Yiqing Lin; David A. Hahn; Carrie A. Coutant; et al. (The AAPS Journal, 2017)

Comparative and population genomic landscape of Phellinus noxius : A hypervariable fungus causing root rot in trees - Chia‐Lin Chung; Tracy J. Lee; Mitsuteru Akiba; Hsin‐Han Lee; Tzu‐Hao Kuo; Dang Liu; Huei‐Mien Ke; Toshiro Yokoi; Marylette B. Roa; Mei‐Yeh J. Lu; Ya‐Yun Chang; Pao‐Jen Ann; et al. (Molecular Ecology, 2017)
The order Hymenochaetales of white rot fungi contain some of the most aggressive wood decayers causing tree deaths around the world. Despite their ecological importance and the impact of diseases they cause, little is known about the evolution and transmission patterns of these pathogens. Here, we sequenced and undertook comparative genomic analyses of Hymenochaetales genomes using brown root rot fungus Phellinus noxius , wood‐decomposing fungus Phellinus lamaensis, laminated root rot fungus Phellinus sulphurascens and trunk pathogen Porodaedalea pini . Many gene families of lignin‐degrading enzymes were identified from these fungi, reflecting their ability as white rot fungi. Comparing against distant fungi highlighted the expansion of 1,3‐beta‐glucan synthases in P. noxius , which may account for its fast‐growing attribute. We identified 13 linkage groups conserved within Agaricomycetes, suggesting the evolution of stable karyotypes. We determined that P. noxius has a bipolar heterothallic mating system, with unusual highly expanded ~60 kb A locus as a result of accumulating gene transposition. We investigated the population genomics of 60 P. noxius isolates across multiple islands of the Asia Pacific region. Whole‐genome sequencing showed this multinucleate species contains abundant poly‐allelic single nucleotide polymorphisms with atypical allele frequencies. Different patterns of intra‐isolate polymorphism reflect mono‐/heterokaryotic states which are both prevalent in nature. We have shown two genetically separated lineages with one spanning across many islands despite the geographical barriers. Both populations possess extraordinary genetic diversity and show contrasting evolutionary scenarios. These results provide a framework to further investigate the genetic basis underlying the fitness and virulence of white rot fungi.

Design, synthesis, antitumor evaluation, 3D-QSAR and molecular docking studies of novel 4-aminoacridone compounds - Lin Tian; Chang J. Feng; Tong X. Li; Zhao Li; Wei H. Yang; Xiang E. Han (Medicinal Chemistry Research, 2017)

PML-IRIS in an HIV-2-infected patient presenting as Bell’s palsy - Fabian Sierra Morales; Carlos Illingworth; Kathie Lin; Ivia Rivera Agosto; Chloé Powell; Jacob A. Sloane; Igor J. Koralnik (Journal of NeuroVirology, 2017)

Construction and functional characterization of truncated versions of recombinant keratanase II from Bacillus circulans - Haisheng Wang; Wenqin He; Peixia Jiang; Yanlei Yu; Lei Lin; Xiaojun Sun; Mattheos Koffas; Fuming Zhang; Robert J. Linhardt (Glycoconjugate Journal, 2017)

The cyclin dependent kinase subunit Cks1 is required for infection‐associated development of the rice blast fungus Magnaporthe oryzae - Xiaofeng Yue; Yawei Que; Shuzhen Deng; Lin Xu; Miriam Oses‐Ruiz; Nicholas J. Talbot; Youliang Peng; Zhengyi Wang (Environmental Microbiology, 2017)
Summary Cell cycle regulation is pivotal for proper cell division and cellular differentiation in eukaryotic cells. The central regulators that govern eukaryotic cell cycle progression are cyclin‐dependent kinases (CDKs) and their partners. Here, we report that Magnaporthe oryzae CKS1 encodes a cyclin‐dependent kinase subunit, which plays a significant role in regulation of plant infection. We demonstrate that CKS1 is a functional homolog of CKS1 / SUC1 and can physically interact with the CDK protein Cdc28, and Som1, a downstream regulator of the cyclic AMP‐dependent Protein Kinase A pathway. CKS1 deletion mutants are severely impaired in hyphal growth, sexual reproduction, melanin pigmentation and conidiogenesis. Cks1 mutants are able to form appressoria from hyphal tips, but these are unable to re‐polarize, and rice infection is impaired. CKS1 also affects chitin and glucan synthase activity during cell wall differentiation and fungal hydrophobin function. CKS1 , therefore, encodes a conserved CDK‐binding partner, essential for appressorium‐mediated plant infection by the rice blast fungus.

Context and craving during stressful events in the daily lives of drug-dependent patients - Kenzie L. Preston; William J. Kowalczyk; Karran A. Phillips; Michelle L. Jobes; Massoud Vahabzadeh; Jia-Ling Lin; Mustapha Mezghanni; David H. Epstein (Psychopharmacology, 2017)

Development of a two-stage washing and biodegradation system to remediate octachlorinated dibenzo-p-dioxin-contaminated soils - J. L. Lin; C. D. Dong; C. W. Chen; S. H. Chen; T. E. Hsieh; C. M. Kao (International Journal of Environmental Science and Technology, 2017)

Helicobacter pylori infection increases the risk of adult-onset asthma: a nationwide cohort study - Y-C Wang; T-Y Lin; S-T Shang; H-J Chen; C-H Kao; C-C Wu; T-Y Yang (European Journal of Clinical Microbiology & Infectious Diseases, 2017)

Microbial manganese(III) reduction fuelled by anaerobic acetate oxidation - Nadia Szeinbaum; Hui Lin; Jay A. Brandes; Martial Taillefert; Jennifer B. Glass; Thomas J. DiChristina (Environmental Microbiology, 2017)
Summary Soluble manganese in the intermediate +III oxidation state (Mn 3+ ) is a newly identified oxidant in anoxic environments, whereas acetate is a naturally abundant substrate that fuels microbial activity. Microbial populations coupling anaerobic acetate oxidation to Mn 3+ reduction, however, have yet to be identified. We isolated a Shewanella strain capable of oxidizing acetate anaerobically with Mn 3+ as the electron acceptor, and confirmed this phenotype in other strains. This metabolic connection between acetate and soluble Mn 3+ represents a new biogeochemical link between carbon and manganese cycles. Genomic analyses uncovered four distinct genes that allow for pathway variations in the complete dehydrogenase‐driven TCA cycle that could support anaerobic acetate oxidation coupled to metal reduction in Shewanella and other Gammaproteobacteria. An oxygen‐tolerant TCA cycle supporting anaerobic manganese reduction is thus a new connection in the manganese‐driven carbon cycle, and a new variable for models that use manganese as a proxy to infer oxygenation events on early Earth.

Formation of chlorite rims and the impact of pore-lining chlorite on reservoir quality: a case study from Shiqianfeng sandstones in upper Permian of Dongpu Depression, Bohai Bay Basin, eastern China - P. J. Ma; C. Y. Lin; S. Q. Zhang; C. M. Dong; Y. F. Xu (Australian Journal of Earth Sciences, 2017)

Risk factors and outcome of levofloxacin-resistant Elizabethkingia meningoseptica bacteraemia in adult patients in Taiwan - Y.-C. Huang; Y.-W. Huang; Y.-T. Lin; F.-D. Wang; Y.-J. Chan; T.-C. Yang (European Journal of Clinical Microbiology & Infectious Diseases, 2017)

Improved genetic parameter estimations in zoysiagrass by implementing post hoc blocking - Lin Xing; Salvador Gezan; Kevin Kenworthy; J. Bryan Unruh; Patricio Munoz (Euphytica, 2017)

Structural and activity variability of fractions with different charge density and chain length from pharmaceutical heparins - Yanlei Yu; Makoto Hirakane; Daisuke Mori; Lei Lin; Fuming Zhang; Hong Zhang; Robert J. Linhardt (Glycoconjugate Journal, 2017)

Taxonomy of the order Mononegavirales: update 2017 - Gaya K. Amarasinghe; Yīmíng Bào; Christopher F. Basler; Sina Bavari; Martin Beer; Nicolás Bejerman; Kim R. Blasdell; Alisa Bochnowski; Thomas Briese; Alexander Bukreyev; Charles H. Calisher; Kartik Chandran; et al. (Archives of Virology, 2017)

Suppressive effect of microRNA319 expression on rice plant height - Wei-Ting Liu; Peng-Wen Chen; Li-Chi Chen; Chia-Chun Yang; Shu-Yun Chen; GuanFu Huang; Tzu Che Lin; Hsin-Mei Ku; Jeremy J. W. Chen (Theoretical and Applied Genetics, 2017)

Controlled Release of Vanadium from a Composite Scaffold Stimulates Mesenchymal Stem Cell Osteochondrogenesis - S. D. Schussler; K. Uske; P. Marwah; F. W. Kemp; J. D. Bogden; S. S. Lin; Treena Livingston Arinzeh (The AAPS Journal, 2017)

Experimental Investigation of the Anisotropic Mechanical Properties of a Columnar Jointed Rock Mass: Observations from Laboratory-Based Physical Modelling - H. Ji; J. C. Zhang; W. Y. Xu; R. B. Wang; H. L. Wang; L. Yan; Z. N. Lin (Rock Mechanics and Rock Engineering, 2017)

Cardiotoxicity Associated with Nicotinamide Phosphoribosyltransferase Inhibitors in Rodents and in Rat and Human-Derived Cells Lines - D. L. Misner; M. A. Kauss; J. Singh; H. Uppal; A. Bruening-Wright; B. M. Liederer; T. Lin; B. McCray; N. La; T. Nguyen; D. Sampath; P. S. Dragovich; et al. (Cardiovascular Toxicology, 2017)

Development of In situ hybridization and real‐time PCR assays for the detection of Hepatospora eriocheir , a microsporidian pathogen in the Chinese mitten crab Eriocheir sinensis - Z F Ding; J Q Chen; J Lin; X S Zhu; G H Xu; R L Wang; Q G Meng; W Wang (Journal of Fish Diseases, 2017)
A microsporidian parasite, Hepatospora eriocheir , is an emerging pathogen for the Chinese mitten crab Eriocheir sinensis . Currently, there is scant information about the way it transmits infection in the crustacean of commercial importance, including its pathogenesis, propagation and infection route in vivo . In this study, chromogenic in situ hybridization ( ISH ) and quantitative real‐time PCR ( qPCR ) assays were developed to address this pressing need, and we provided an advance in the detection methods available. Pathogens can be seen in situ with associated lesions using ISH . Positive hybridization signals were noted inside the epithelial cells of the hepatopancreas, and putative free parasite spores were observed within the tubule lumen, which were associated with lesions detected by electron microscopy and haematoxylin and eosin (H&E) analysis. qPCR allows the determination of parasite loads in infected tissues, which is important for understanding disease progression and transmission. The hepatopancreas displayed the biggest statistical copy numbers among different tissues of infected crabs, confirming a tissue‐specific pathogen infection characteristic. The qPCR assay also proved to be suitable for the diagnosis of asymptomatic carrier crabs. Combination of the two methods could facilitate the study of H. eriocheir infection mechanism in E. sinensis , enhance the early diagnosis of the pathogen and improve the management of microsporidian diseases in commercial crustaceans.

The role of functional uniqueness and spatial aggregation in explaining rarity in trees - María Natalia Umaña; Xiangcheng Mi; Min Cao; Brian J. Enquist; Zhanqing Hao; Robert Howe; Yoshiko Iida; Daniel Johnson; Luxiang Lin; Xiaojuan Liu; Keping Ma; I‐Fang Sun; et al. (Global Ecology and Biogeography, 2017)
Aim Determining the drivers of species rarity is fundamental for understanding and conserving biodiversity. Rarity of a given species within its community may arise due to exclusion by other ecologically similar species. Conversely, rare species may occupy habitats that are rare in the landscape or they may be ill‐suited to all available habitats. The first mechanism would lead to common and rare species occupying similar ecological space defined by functional traits. The second mechanism would result in common and rare species occupying dissimilar ecological space and spatial aggregation of rare species, either because they are specialists in rare habitats or because rare species tend to be dispersal limited. Here, we quantified the contribution of locally rare species to community functional richness and the spatial aggregation of species across tree communities world‐wide to address these hypotheses. Location Asia and the Americas. Time period 2002 to 2012 (period that considers the censuses for the plots used). Major taxa studied Angiosperm and Gymnosperm trees. Methods We compiled a dataset of functional traits from all the species present in eight tree plots around the world to evaluate the contribution of locally rare species to tree community functional richness using multi‐ and univariate approaches. We also quantified the spatial aggregation of individuals within species at several spatial scales as it relates to abundance. Results Locally rare tree species in temperate and tropical forests tended to be functionally unique and are consistently spatially clustered. Furthermore, there is no evidence that this pattern is driven by pioneer species being locally rare. Main conclusions This evidence shows that locally rare tree species disproportionately contribute to community functional richness, and we can therefore reject the hypothesis that locally rare species are suppressed by ecologically similar, but numerically dominant, species. Rather, locally rare species are likely to be specialists on spatially rare habitats or they may be ill‐suited to the locally available environments.

Loss of the ssrA genome island led to partial debromination in the PBDE respiring Dehalococcoides mccartyi strain GY50 - Chang Ding; Matthew J. Rogers; Kun‐Lin Yang; Jianzhong He (Environmental Microbiology, 2017)
Summary Polybrominated diphenyl ethers (PBDEs), chemicals commonly used as flame‐retardants in consumer products, are emerging persistent organic pollutants that are ubiquitous in the environment. In this study, we report a PBDE‐respiring isolate – Dehalococcoides mccartyi strain GY50, which debrominates the most toxic tetra‐ and penta‐BDE congeners (∼1.4 µM) to diphenyl ether within 12 days with hydrogen as the electron donor. The complete genome sequence revealed 26 reductive dehalogenase homologous genes ( rdhA s), among which three genes ( pbrA1 , pbrA2 and pbrA3 ) were highly expressed during PBDE debromination. After 10 transfers of GY50 with trichloroethene or 2,4,6‐trichlorophenol as the electron acceptor instead of PBDEs, the ssrA ‐specific genome island ( ssrA ‐GI) containing pbrA1 and pbrA2 was deleted from the genome of strain GY50, leading to two variants (strain GY52 with trichloroethene, strain GY55 with 2,4,6‐trichlorophenol) with identically impaired debromination capabilities (debromination of penta‐/tetra‐BDEs ceased at di‐BDE 15). Through analysis of Illumina paired‐end sequencing data, we identified read pairs that probably came from variants that contain ssrA ‐GI deletions, indicating their possible presence in the original strain GY50 culture. The two variant strains provide real‐time examples on rapid evolution of organohalide‐respiring organisms. As PBDE‐respiring organisms, GY50‐like strains may serve as key players in detoxifying PBDEs in contaminated environments.

Abnormal Effective Connectivity in the Brain is Involved in Auditory Verbal Hallucinations in Schizophrenia - Baojuan Li; Long-Biao Cui; Yi-Bin Xi; Karl J. Friston; Fan Guo; Hua-Ning Wang; Lin-Chuan Zhang; Yuan-Han Bai; Qing-Rong Tan; Hong Yin; Hongbing Lu (Neuroscience Bulletin, 2017)

Selective Isolation of a Eucalyptus spp. Woodchip Bacterial Community and Its Taxonomic and Metabolic Profiling - C. F. Nnadozie; J. Lin; R. Govinden (BioEnergy Research, 2017)

Mitigation of inbreeding while preserving genetic gain in genomic breeding programs for outbred plants - Zibei Lin; Fan Shi; Ben J. Hayes; Hans D. Daetwyler (Theoretical and Applied Genetics, 2017)

Genetic Variants of Microtubule Actin Cross-linking Factor 1 (MACF1) Confer Risk for Parkinson’s Disease - Xin Wang; Nuomin Li; Nian Xiong; Qi You; Jie Li; Jinlong Yu; Hong Qing; Tao Wang; Heather J. Cordell; Ole Isacson; Jeffery M. Vance; Eden R. Martin; et al. (Molecular Neurobiology, 2017)

Gonorrhea infection increases the risk of prostate cancer in Asian population: a nationwide population-based cohort study - Y.-C. Wang; C.-H. Chung; J.-H. Chen; M.-H. Chiang; Ti-Yin; C.-H. Tsao; F.-H. Lin; W.-C. Chien; S.-T. Shang; F.-Y. Chang (European Journal of Clinical Microbiology & Infectious Diseases, 2017)

Indole signalling and (micro)algal auxins decrease the virulence of V ibrio campbellii , a major pathogen of aquatic organisms - Qian Yang; Gde Sasmita Julyantoro Pande; Zheng Wang; Baochuan Lin; Robert A. Rubin; Gary J. Vora; Tom Defoirdt (Environmental Microbiology, 2017)
Summary Vibrios belonging to the Harveyi clade are major pathogens of marine vertebrates and invertebrates, causing major losses in wild and cultured organisms. Despite their significant impact, the pathogenicity mechanisms of these bacteria are not yet completely understood. In this study, the impact of indole signalling on the virulence of Vibrio campbellii was investigated. Elevated indole levels significantly decreased motility, biofilm formation, exopolysaccharide production and virulence to crustacean hosts. Indole furthermore inhibited the three‐channel quorum sensing system of V. campbellii , a regulatory mechanism that is required for full virulence of the pathogen. Further, indole signalling was found to interact with the stress sigma factor RpoS. Together with the observations that energy‐consuming processes (motility and bioluminescence) are downregulated, and microarray‐based transcriptomics demonstrating that indole decreases the expression of genes involved in energy and amino acid metabolism, the data suggest that indole is a starvation signal in V. campbellii . Finally, it was found that the auxins indole‐3‐acetic acid and indole‐3‐acetamide, which were produced by various (micro)algae sharing the aquatic environment with V. campbellii , have a similar effect as observed for indole. Auxins might, therefore, have a significant impact on the interactions between vibrios, (micro)algae and higher organisms, with major ecological and practical implications.

Social implications of fission in wild Formosan macaques at Mount Longevity, Taiwan - Minna J. Hsu; Jin-Fu Lin; Govindasamy Agoramoorthy (Primates, 2017)

Subsessila turbinata gen. et. sp. nov. (Beltraniaceae), a Beltrania-like fungus from Thailand - Chuan-Gen Lin; Dong-Qin Dai; Darbhe J. Bhat; Kevin D. Hyde; Li-Zhou Tang; Chaiwat To-anun (Mycological Progress, 2017)

Functional near-infrared spectroscopy (fNIRS) brain imaging of multi-sensory integration during computerized dynamic posturography in middle-aged and older adults - Chia-Cheng Lin; Jeffrey W. Barker; Patrick J. Sparto; Joseph M. Furman; Theodore J. Huppert (Experimental Brain Research, 2017)

Increased risk of chronic osteomyelitis after hip replacement: a retrospective population-based cohort study in an Asian population - D.-Z. Hung; N. Tien; C.-L. Lin; Y.-R. Lee; C. C. N. Wang; J.-J. Chen; Y.-P. Lim (European Journal of Clinical Microbiology & Infectious Diseases, 2017)

Soil priming effects following substrates addition to biochar-treated soils after 431 days of pre-incubation - Yu Luo; Qimei Lin; M. Durenkamp; A. J. Dungait; P. C. Brookes (Biology and Fertility of Soils, 2017)

Heat budget of the western Pacific warm pool and the contribution of eddy heat transport diagnosed from HYCOM assimilation - J. Chi; P. Shi; W. Zhuang; X. Lin; X. Cheng; Yan Du (Journal of Oceanography, 2017)

Myosin II sequences for Lethocerus indicus - Lanette Fee; Weili Lin; Feng Qiu; Robert J. Edwards (Journal of Muscle Research and Cell Motility, 2017)

Experimental and statistical methods to evaluate antibacterial activity of a quaternary pyridinium salt on planktonic, biofilm-forming, and biofilm states - Daneli López Pérez; Paula J. Baker; Adam L. Pintar; Jirun Sun; Nancy J. Lin; Sheng Lin-Gibson (Biofouling, 2017)

Glycerol enhances fungal germination at the water‐activity limit for life - Andrew Stevenson; Philip G. Hamill; Ángel Medina; Gerhard Kminek; John D. Rummel; Jan Dijksterhuis; David J. Timson; Naresh Magan; Su‐Lin L. Leong; John E. Hallsworth (Environmental Microbiology, 2017)
Summary For the most‐extreme fungal xerophiles, metabolic activity and cell division typically halts between 0.700 and 0.640 water activity (approximately 70.0–64.0% relative humidity). Here, we investigate whether glycerol can enhance xerophile germination under acute water‐activity regimes, using an experimental system which represents the biophysical limit of Earth's biosphere. Spores from a variety of species, including Aspergillus penicillioides , Eurotium halophilicum , Xerochrysium xerophilum (formerly Chrysosporium xerophilum ) and Xeromyces bisporus , were produced by cultures growing on media supplemented with glycerol (and contained up to 189 mg glycerol g dry spores −1 ). The ability of these spores to germinate, and the kinetics of germination, were then determined on a range of media designed to recreate stresses experienced in microbial habitats or anthropogenic systems (with water‐activities from 0.765 to 0.575). For A. penicillioides , Eurotium amstelodami , E. halophilicum , X. xerophilum and X. bisporus , germination occurred at lower water‐activities than previously recorded (0.640, 0.685, 0.651, 0.664 and 0.637 respectively). In addition, the kinetics of germination at low water‐activities were substantially faster than those reported previously. Extrapolations indicated theoretical water‐activity minima below these values; as low as 0.570 for A. penicillioides and X. bisporus . Glycerol is present at high concentrations (up to molar levels) in many types of microbial habitat. We discuss the likely role of glycerol in expanding the water‐activity limit for microbial cell function in relation to temporal constraints and location of the microbial cell or habitat. The findings reported here have also critical implications for understanding the extremes of Earth's biosphere; for understanding the potency of disease‐causing microorganisms; and in biotechnologies that operate at the limits of microbial function.

A Review of the Functional and Anatomical Default Mode Network in Schizophrenia - Mao-Lin Hu; Xiao-Fen Zong; J. John Mann; Jun-Jie Zheng; Yan-Hui Liao; Zong-Chang Li; Ying He; Xiao-Gang Chen; Jin-Song Tang (Neuroscience Bulletin, 2017)

Variability of hydrological extreme events in East Asia and their dynamical control: a comparison between observations and two high-resolution global climate models - N. Freychet; A. Duchez; C.-H. Wu; C.-A. Chen; H.-H. Hsu; J. Hirschi; A. Forryan; B. Sinha; A. L. New; T. Graham; M. B. Andrews; C.-Y. Tu; et al. (Climate Dynamics, 2017)

Recent declines in cancer incidence: related to the Great Recession? - Scarlett Lin Gomez; Alison J. Canchola; David O. Nelson; Theresa H. M. Keegan; Christina A. Clarke; Iona Cheng; Salma Shariff-Marco; Mindy DeRouen; Ralph Catalano; William A. Satariano; Kathleen Davidson-Allen; Sally L. Glaser (Cancer Causes & Control, 2017)

Dual action of peroxisome proliferator-activated receptor alpha in perfluorodecanoic acid-induced hepatotoxicity - Min Luo; Zhen Tan; Manyun Dai; Danjun Song; Jiao Lin; Minzhu Xie; Julin Yang; Lu Sun; Dengming Wei; Jinshun Zhao; Frank J. Gonzalez; Aiming Liu (Archives of Toxicology, 2017)

Transcriptomic imprints of adaptation to fresh water: parallel evolution of osmoregulatory gene expression in the Alewife - Jonathan P. Velotta; Jill L. Wegrzyn; Samuel Ginzburg; Lin Kang; Sergiusz Czesny; Rachel J. O'Neill; Stephen D. McCormick; Pawel Michalak; Eric T. Schultz (Molecular Ecology, 2017)
Comparative approaches in physiological genomics offer an opportunity to understand the functional importance of genes involved in niche exploitation. We used populations of Alewife ( Alosa pseudoharengus ) to explore the transcriptional mechanisms that underlie adaptation to fresh water. Ancestrally anadromous Alewives have recently formed multiple, independently derived, landlocked populations, which exhibit reduced tolerance of saltwater and enhanced tolerance of fresh water. Using RNA ‐seq, we compared transcriptional responses of an anadromous Alewife population to two landlocked populations after acclimation to fresh (0 ppt) and saltwater (35 ppt). Our results suggest that the gill transcriptome has evolved in primarily discordant ways between independent landlocked populations and their anadromous ancestor. By contrast, evolved shifts in the transcription of a small suite of well‐characterized osmoregulatory genes exhibited a strong degree of parallelism. In particular, transcription of genes that regulate gill ion exchange has diverged in accordance with functional predictions: freshwater ion‐uptake genes (most notably, the ‘freshwater paralog’ of Na + /K + ‐ ATP ase α‐subunit) were more highly expressed in landlocked forms, whereas genes that regulate saltwater ion secretion (e.g. the ‘saltwater paralog’ of NKA α) exhibited a blunted response to saltwater. Parallel divergence of ion transport gene expression is associated with shifts in salinity tolerance limits among landlocked forms, suggesting that changes to the gill's transcriptional response to salinity facilitate freshwater adaptation.

Structuraland antigenic analysis of a new Rhoptry Pseudokinase Gene (ROP54) in Toxoplasma gondii - Jian Zhou; Gang Lu; Lin Wang; Aihua H. Zhou; Yali L. Han; Jingjing J. Guo; Pengxia X. Song; Huaiyu Y. Zhou; Hua Cong; Ming Hou; Shenyi Y. He (Acta Parasitologica, 2017)
is defined as an obligate intracellular apicomplexan parasite and influences approximatelyone-third of the human all over the world. ROP54 protein is expressed in the rhoptry of

Co‐existence of distinct Ostreococcus ecotypes at an oceanic front - Sophie Clayton; Yun‐Chi Lin; Michael J. Follows; Alexandra Z. Worden (Limnology and Oceanography, 2017)
Western boundary currents support high primary production and carbon export. Here, we performed a survey of photosynthetic picoeukaryotes in the North Pacific Ocean in four transects crossing the Kuroshio Front. Prasinophyte algae comprised 85% of 18S rRNA gene sequences for photosynthetic taxa in the Micromonas and Ostreococcus comprised 30% and 51% of the total photosynthetic 18S rDNA sequences from five stations. Phylogenetic analysis showed that two Ostreococcus ecotypes, until now rarely found to co‐occur, were both present in the majority of samples. Ostreococcus ecotype OI reached 6,830 ± 343 gene copies mL −1 , while Ostreococcus ecotype OII reached 50,190 ± 971 gene copies mL −1 based on qPCR analysis of the 18S rRNA gene. These values are higher than in studies of other oceanographic regions by a factor of 10 for OII. The data suggest that meso‐ and finer‐scale physical dynamics had a significant impact on the populations at the front, either by mingling ecotypes from different source regions at fine scales (∼10s km) or by stimulating their growth through vertical nutrient injections. We investigate this hypothesis with an idealized diffusion‐reaction model, and find that only a combination of mixing and positive net growth can explain the observed distributions and overlap of the two Ostreococcus ecotypes. Our field observations support larger‐scale numerical ocean simulations that predict enhanced biodiversity at western boundary current fronts, and suggest a strategy for systematically testing that hypothesis.

The Diagnosis and Natural History of Multiple System Atrophy, Cerebellar Type - David J. Lin; Katherine L. Hermann; Jeremy D. Schmahmann (The Cerebellum, 2016)

Generating Random Earthquake Events for Probabilistic Tsunami Hazard Assessment - Randall J. LeVeque; Knut Waagan; Frank I. González; Donsub Rim; Guang Lin (Pure and Applied Geophysics, 2016)

Traits of dominant tree species predict local scale variation in forest aboveground and topsoil carbon stocks - Dunmei Lin; Kristina J. Anderson-Teixeira; Jiangshan Lai; Xiangcheng Mi; Haibao Ren; Keping Ma (Plant and Soil, 2016)

The genus Fusariella - Chuan-Gen Lin; Yun Chen; Eric H. C. McKenzie; Darbhe J. Bhat; Hiran A. Ariyawansa; Kevin D. Hyde; Yong Wang (Mycological Progress, 2016)

An unusual Lophodermium species on needles of Pinus taiwanensis from China - Zhi-Jie Li; J. E. Taylor; Cheng-Lin Hou (Mycological Progress, 2016)

Multiple-factor classification of a human-modified forest landscape in the Hsuehshan Mountain Range, Taiwan - Kevan J. Berg; Lahuy Icyeh; Yih-Ren Lin; Arnold Janz; Steven G. Newmaster (Ambio, 2016)

Functional composition drives ecosystem function through multiple mechanisms in a broadleaved subtropical forest - Jyh-Min Chiang; Marko J. Spasojevic; Helene C. Muller-Landau; I-Fang Sun; Yiching Lin; Sheng-Hsin Su; Zueng-Sang Chen; Chien-Teh Chen; Nathan G. Swenson; Ryan W. McEwan (Oecologia, 2016)

Plant adaptation or acclimation to rising CO 2 ? Insight from first multigenerational RNA‐Seq transcriptome - Alexander Watson‐Lazowski; Yunan Lin; Franco Miglietta; Richard J. Edwards; Mark A. Chapman; Gail Taylor (Global Change Biology, 2016)
Atmospheric carbon dioxide ( CO 2 ) directly determines the rate of plant photosynthesis and indirectly effects plant productivity and fitness and may therefore act as a selective pressure driving evolution, but evidence to support this contention is sparse. Using Plantago lanceolata L. seed collected from a naturally high CO 2 spring and adjacent ambient CO 2 control site, we investigated multigenerational response to future, elevated atmospheric CO 2 . Plants were grown in either ambient or elevated CO 2 (700 μmol mol −1 ), enabling for the first time, characterization of the functional and population genomics of plant acclimation and adaptation to elevated CO 2 . This revealed that spring and control plants differed significantly in phenotypic plasticity for traits underpinning fitness including above‐ground biomass, leaf size, epidermal cell size and number and stomatal density and index. Gene expression responses to elevated CO 2 (acclimation) were modest [33–131 genes differentially expressed ( DE )], whilst those between control and spring plants (adaptation) were considerably larger (689–853 DE genes). In contrast, population genomic analysis showed that genetic differentiation between spring and control plants was close to zero, with no fixed differences, suggesting that plants are adapted to their native CO 2 environment at the level of gene expression. An unusual phenotype of increased stomatal index in spring but not control plants in elevated CO 2 correlated with altered expression of stomatal patterning genes between spring and control plants for three loci ( YODA , CDKB 1;1 and SCRM 2 ) and between ambient and elevated CO 2 for four loci ( ER , YODA , MYB 88 and BCA 1 ). We propose that the two positive regulators of stomatal number ( SCRM 2 ) and CDKB 1;1 when upregulated act as key controllers of stomatal adaptation to elevated CO 2 . Combined with significant transcriptome reprogramming of photosynthetic and dark respiration and enhanced growth in spring plants, we have identified the potential basis of plant adaptation to high CO 2 likely to occur over coming decades.

Limited diversity associated with duplicated class II MHC-DRB genes in the red squirrel population in the United Kingdom compared with continental Europe - Keith T. Ballingall; Angeline McIntyre; Zhenzhen Lin; Naomi Timmerman; Erik Matthysen; Peter W.W. Lurz; Lynsey Melville; Amy Wallace; Anna L. Meredith; Claudia Romeo; Lucas A. Wauters; Anthony W. Sainsbury; et al. (Conservation Genetics, 2016)

A prognostic model for advanced colorectal neoplasia recurrence - Lin Liu; Karen Messer; John A. Baron; David A. Lieberman; Elizabeth T. Jacobs; Amanda J. Cross; Gwen Murphy; Maria Elena Martinez; Samir Gupta (Cancer Causes & Control, 2016)

Effects of probiotics on soil microbial activity, biomass and enzymatic activity under cover crops in field and greenhouse studies - Ahsan M. Rajper; Ranjith P. Udawatta; Robert J. Kremer; Chung-ho Lin; Shibu Jose (Agroforestry Systems, 2016)

The agranular and granular insula differentially contribute to gambling-like behavior on a rat slot machine task: effects of inactivation and local infusion of a dopamine D4 agonist on reward expectancy - P. J. Cocker; M. Y. Lin; M. M. Barrus; B. Le Foll; C. A. Winstanley (Psychopharmacology, 2016)

Convergence and divergence in a long‐term old‐field succession: the importance of spatial scale and species abundance - Shao‐peng Li; Marc W. Cadotte; Scott J. Meiners; Zhichao Pu; Tadashi Fukami; Lin Jiang (Ecology Letters, 2016)
Whether plant communities in a given region converge towards a particular stable state during succession has long been debated, but rarely tested at a sufficiently long time scale. By analysing a 50‐year continuous study of post‐agricultural secondary succession in New Jersey, USA , we show that the extent of community convergence varies with the spatial scale and species abundance classes. At the larger field scale, abundance‐based dissimilarities among communities decreased over time, indicating convergence of dominant species, whereas incidence‐based dissimilarities showed little temporal tend, indicating no sign of convergence. In contrast, plots within each field diverged in both species composition and abundance. Abundance‐based successional rates decreased over time, whereas rare species and herbaceous plants showed little change in temporal turnover rates. Initial abandonment conditions only influenced community structure early in succession. Overall, our findings provide strong evidence for scale and abundance dependence of stochastic and deterministic processes over old‐field succession.

Genetic Diversity of Populations of Saccharum spontaneum with Different Ploidy Levels Using SSR Molecular Markers - X. L. Liu; X. J. Li; C. H. Xu; X. Q. Lin; Z. H. Deng (Sugar Tech, 2016)

Changes in Sulforaphane and Selenocysteine Methyltransferase Transcript Levels in Broccoli Treated with Sodium Selenite - K. Huang; J. C. Lin; Q. Y. Wu; J. Y. Yan; M. Y. Liu; S. Zhang; W. J. Xiao (Plant Molecular Biology Reporter, 2016)

Parasitism Performance of Tetrastichus brontispae Ferriere over the Coconut Hispine Beetle, Brontispa longissima (Gestro) - K Liu; B L Fu; J R Lin; Y G Fu; Z Q Peng; Q A Jin; L D Tang (Neotropical Entomology, 2016)

Cannibalistic viruses in the aquatic environment: role of virophages in manipulating microbial communities - V. Marie; J. Lin (International Journal of Environmental Science and Technology, 2016)

Taxonomy of the order Mononegavirales: update 2016 - Claudio L. Afonso; Gaya K. Amarasinghe; Krisztián Bányai; Yīmíng Bào; Christopher F. Basler; Sina Bavari; Nicolás Bejerman; Kim R. Blasdell; François-Xavier Briand; Thomas Briese; Alexander Bukreyev; Charles H. Calisher; et al. (Archives of Virology, 2016)

Clinical characteristics and outcomes of veterans hospitalised with purulent soft tissue infections with and without systemic signs of infection - Craig G. Gunderson; Jurgen Holleck; John J. Chang; Shin Lin; Naseema Merchant; Shaili Gupta (Infectious Diseases, 2016)

Chidamide alleviates TGF-β-induced epithelial–mesenchymal transition in lung cancer cell lines - Sheng-Hao Lin; Bing-Yen Wang; Ching-Hsiung Lin; Peng-Ju Chien; Yueh-Feng Wu; Jiunn-Liang Ko; Jeremy J. W. Chen (Molecular Biology Reports, 2016)

Deep sequencing of banana bract mosaic virus from flowering ginger (Alpinia purpurata) and development of an immunocapture RT-LAMP detection assay - Jingxin Zhang; Wayne B. Borth; Birun Lin; Kishore K. Dey; Michael J. Melzer; Huifang Shen; Xiaoming Pu; Dayuan Sun; John S. Hu (Archives of Virology, 2016)

Differentiation in development of benzimidazole resistance in Colletotrichum gloeosporioides complex populations from strawberry and grape hosts - T. Lin; X. F. Xu; D. J. Dai; H. J. Shi; H. D. Wang; C. Q. Zhang (Australasian Plant Pathology, 2016)

Genomic variability and molecular evolution of Asian isolates of sugarcane streak mosaic virus - Shan-Shan Liang; Olufemi J. Alabi; Mona B. Damaj; Wei-Lin Fu; Sheng-Ren Sun; Hua-Ying Fu; Ru-Kai Chen; T. Erik Mirkov; San-Ji Gao (Archives of Virology, 2016)