Rose Bengal inhibits β-amyloid oligomers-induced tau hyperphosphorylation via acting on Akt and CDK5 kinases - Chen-Ye Mou; Yan-Fei Xie; Jia-Xin Wei; Qi-Yao Wang; Jing-Yang Le; Yong-Jie Bao; Pan-Pan Zhang; Yue-Chun Mao; Xing-Han Huang; Han-Bo Pan; C. Benjamin Naman; Lin Liu; et al. (Psychopharmacology, 2022)

Dual Effects of Light on Regulating Aedes aegypti Heat-Seeking Behavior - Haonan Zhou; Kai Shi; Fengming Wu; Bingcai Wang; Jing Li; Bowen Deng; Chuan Zhou (Neuroscience Bulletin, 2022)

Isobavachalcone’s Alleviation of Pyroptosis Contributes to Enhanced Apoptosis in Glioblastoma: Possible Involvement of NLRP3 - Yueshan Wu; Jing Chang; Juanjuan Ge; Kangyan Xu; Quan Zhou; Xiaowen Zhang; Ni Zhu; Meichun Hu (Molecular Neurobiology, 2022)

Efficient side-chain deacylation of polymyxin B1 in recombinant Streptomyces strains - Xiaojing Wang; Kai Wu; Hanzhi Zhang; Jing Liu; Zhijun Yang; Jing Bai; Hao Liu; Lei Shao (Biotechnology Letters, 2022)

The critical role of the orbitofrontal cortex for regret in an economic decision-making task - Tingting Zhang; Qiuzhu Zhang; Jiaqi Wu; Min Wang; Wenjuan Li; Jing Yan; Junjun Zhang; Zhenlan Jin; Ling Li (Brain Structure and Function, 2022)

Mechanism of the rock stratum resisting inrush in filling-type karst tunnels and its application - Daliang Zhang; Lei Gao; Jing Wu (Arabian Journal of Geosciences, 2022)

Comparison of metabolome profiles in zebrafish (Danio rerio) intestine induced by polystyrene microplastics with different sizes - Jing Yu; Weiqing Gu; Ling Chen; Bing Wu (Environmental Science and Pollution Research, 2022)

Effects of initial particle sizes of Triarrhena lutarioriparia on processing performance, material properties, and heavy metal speciation in sewage sludge composting - Min Ruan; Yanru Zhang; Xikai Wu; Yutong Sun; Zhongliang Huang; Hui Li; Zhangmao Hu; Zijian Wu; Xuan Zhang; Xiaoli Qin; Jing Huang (Environmental Science and Pollution Research, 2022)

Cessation of collisional tectonism and rapid crustal uplift recorded by 430–420 Ma igneous rocks in the South Kunlun belt, northwest China - Jing Chen; Bing-Zhang Wang; Fu-Cheng Yu; Jie Han; Wu-Fu Li (International Geology Review, 2022)

Numerical and Experimental Study on the Bragg Reflection of Water Waves by Multiple Vertical Thin Plates - Wei-Wei Ding; Wan-Zhen Yue; Song-Wei Sheng; Jing-Ping Wu; Zao-Jian Zou (Journal of Marine Science and Engineering, 2022)
The Bragg reflection of water waves by multiple vertical thin plates is investigated numerically and experimentally. The problem of surface gravity wave interaction with multiple vertical thin plates is formulated mathematically under the assumption of linear water wave theory. Numerical results of the reflection and transmission coefficients are obtained based on the dual boundary element method and compared with the results in the literature. The characteristics of Bragg reflection are represented by the occurring condition, the primary reflection coefficient and the effective bandwidth. The effects of the number, the immerged depth and the spacing of the plates on the characteristics of Bragg reflection are further analyzed systematically. Model experiments are conducted and the experimental results are used to compare with the numerical results of Bragg reflection. This study can provide guidance on the design of multiple vertical thin plates as effective breakwaters by taking advantage of Bragg reflection.

Exploring feedback mechanisms for nitrogen and organic carbon cycling in tropical coastal zones - Shan Jiang; Laiqun Jin; Jie Jin; Juan Severino Pino Ibánhez; Ying Wu; Jing Zhang (Frontiers in Marine Science, 2022)
The anthropogenic introduction of significant amounts of reactive nitrogen in the coastal zone particularly since the discovery and application of the Haber-Bosch process has profound consequences over organic carbon storage and transformations at both regional and global scales. Here, we review our current knowledge on cause-effect chains for nitrogen, especially dissolved inorganic nitrogen, on organic carbon cycling in coastal tropical systems. We focus on the feedback mechanisms for turnover of different organic carbon species to nitrogen excess and links to current environmental and climate changes. We pay special attention to organic carbon dynamics in tropical coasts due to their high primary productivity, rapid sedimentation, and significant needs of nitrogen for agriculture and industry usages. Together with land-use changes and economy development, we highlight the vulnerability of carbon storage in tropical coasts triggered by nitrogen overloading and outline possible industrial strategies with low carbon cycling disturbance to benefit the development of tropical countries.

Xylomexicanins K-N: limonoids from the leaves and twigs of Xylocarpus granatum - Shao-Jing Li; Li-Kang Zhao; Jin-Jun Chen; Chun-Hua Zhou; Xin-Li Huang; Yi-Bing Wu; Françoise Sauriol; Yu-Cheng Gu; Hiromasa Kiyota (Natural Product Research, 2022)

SSR-Based Molecular Identification and Population Structure Analysis for the Yunrui-Series Sugarcane (Saccharum spp. Hybrids) Genotypes - Chunyan Tian; Jianrong Zhu; Yongbao Pan; Xin Lu; Lihua Dong; David M. Burner; Lianan Tao; Caiwen Wu; Yanfen Jing (Sugar Tech, 2022)

Molecular modification of Bacillus stearothermophilus NO2 cyclodextrin glucosyltransferase and preparation of α-cyclodextrin - Fangyuan Zuo; Lingqia Su; Demin Kong; Lei Wang; Jing Wu; Sheng Chen (Systems Microbiology and Biomanufacturing, 2022)

Enhancing the thermostability of d-allulose 3-epimerase from Clostridium cellulolyticum H10 via directed evolution - Shuhan Liu; Yifan Wang; Demin Kong; Jing Wu; Zhanzhi Liu (Systems Microbiology and Biomanufacturing, 2022)

Mesenchymal Stem Cells Alleviate Inflammatory Bowel Disease Via Tr1 Cells - Lingli Qi; Jing Wu; Shan Zhu; Xue Wang; Xinping Lv; Chunyan Liu; Yong-Jun Liu; Jingtao Chen (Stem Cell Reviews and Reports, 2022)

MYOCD is Required for Cardiomyocyte-like Cells Induction from Human Urine Cells and Fibroblasts Through Remodeling Chromatin - Xiangyu Zhang; Lijun Chen; Xingnan Huang; Huan Chen; Baomei Cai; Yue Qin; Yating Chen; Sihua Ou; Xiaoxi Li; Zichao Wu; Ziyu Feng; Mengying Zeng; et al. (Stem Cell Reviews and Reports, 2022)

Ketamine induces rapid antidepressant effects via the autophagy-NLRP3 inflammasome pathway - Dongbin Lyu; Fan Wang; Mengke Zhang; Weichieh Yang; Haijing Huang; Qinte Huang; Chenglin Wu; Nuoshi Qian; Meiti Wang; Huanfei Zhang; Sichai Zheng; Jing Chen; et al. (Psychopharmacology, 2022)

Schisandra chinensis (Turcz.) Baill. essential oil exhibits antidepressant-like effects and against brain oxidative stress through Nrf2/HO-1 pathway activation - Liang Tan; Yunfang Yang; Jing Peng; Yue Zhang; Bo Wu; Bosai He; Ying Jia; Tingxu Yan (Metabolic Brain Disease, 2022)

Spatial distribution, food chain translocation, human health risks, and environmental thresholds of heavy metals in a maize cultivation field in the heart of China’s karst region - Wentao Yang; Yonglin Chen; Liyu Yang; Mengqi Xu; Haonan Jing; Pan Wu; Ping Wang (Journal of Soils and Sediments, 2022)

Maternal exposure to cooking oil fumes during pregnancy and autistic‐like behaviors in Chinese preschoolers - Jian-Hui Yang; Esben Strodl; Chuan-An Wu; Xiang-Yu Hou; Xiao-Na Yin; Guo-Min Wen; Deng-Li Sun; Dan-Xia Xian; Jing-Yi Chen; Ying-Jie Chen; Jing Chen; Wei-Qing Chen (Environmental Science and Pollution Research, 2022)

Relationship between urinary dichlorophenols and cognitive function among people over 60 years old from NHANES - Xueqiong Weng; Huanzhu Liang; Kun Liu; Jingmin Chen; Qiaoyuan Fei; Shan Liu; Xinrong Guo; Lin Wen; Yingying Wu; Zhiqiang Nie; Chunxia Jing (Environmental Science and Pollution Research, 2022)

Ambient gaseous pollutant exposure and incidence of visual impairment among children and adolescents: findings from a longitudinal, two-center cohort study in China - Li Chen; Jing Wei; Tao Ma; Di Gao; Xijie Wang; Bo Wen; Manman Chen; Yanhui Li; Jun Jiang; Lijuan Wu; Weiming Li; Xiangtong Liu; et al. (Environmental Science and Pollution Research, 2022)

Association between short-term exposure to ambient PM1 and PM2.5 and forced vital capacity in Chinese children and adolescents - Han Wu; Yingxiu Zhang; Jing Wei; Pascal Bovet; Min Zhao; Wenhui Liu; Bo Xi (Environmental Science and Pollution Research, 2022)

Risk of thyroid cancer and benign nodules associated with exposure to parabens among Chinese adults in Wuhan, China - Nan-Xin Wu; Lang-Jing Deng; Feng Xiong; Jin-Ying Xie; Xiao-Jie Li; Qiang Zeng; Jia-Chen Sun; Da Chen; Pan Yang (Environmental Science and Pollution Research, 2022)

Starch, cellulose and plant extracts as green inhibitors of metal corrosion: a review - Li Huang; Wei-Qiang Chen; Shan-Shan Wang; Qing Zhao; Hui-Jing Li; Yan-Chao Wu (Environmental Chemistry Letters, 2022)

High-resolution mapping of premature mortality induced by atmospheric particulate matter in China - Sheng Zheng; Xue Wu; Eric Lichtfouse; Jing Wang (Environmental Chemistry Letters, 2022)

Detecting and monitoring tumors in orthotopic colorectal liver metastatic animal models with high-resolution ultrasound - Shengcai Wei; Yiqun Liu; Yuwei Xin; Caizhen Feng; Yinli Zhang; Xiaoxuan Jia; Fan Chai; Jiaqi Zhao; Yulu Liu; Xun Yao; Xiaoyi Liu; Jing Wu; et al. (Clinical & Experimental Metastasis, 2022)

Dynamic Effect of Organic Fertilizer Application on Rice Growth, Soil Physicochemical Properties and Cd Activity Exposed to Excess Cd - Liyu Yang; Mengqi Xu; Yonglin Chen; Haonan Jing; Jia Zhang; Wentao Yang; Pan Wu (Bulletin of Environmental Contamination and Toxicology, 2022)

The distinct disrupted plasticity in structural and functional network in mild stroke with basal ganglia region infarcts - Hua Zhu; Lijun Zuo; Wanlin Zhu; Jing Jing; Zhe Zhang; Lingling Ding; Fengjuan Wang; Jian Cheng; Zhenzhou Wu; Yongjun Wang; Tao Liu; Zixiao Li (Brain Imaging and Behavior, 2022)

Degradation characteristics of crude oil by a consortium of bacteria in the existence of chlorophenol - Jing Li; Qiyou Liu; Shuo Sun; Xiuxia Zhang; Xiuying Zhao; Junlong Yu; Wu Cui; Yi Du (Biodegradation, 2022)

Structural elucidation, anti-radical and immunomodulatory activities of polysaccharides from the roots of Glehnia littoralis - Yongshuai Jing; Ruijuan Zhang; Yunfeng Ma; Yuwei Zhang; Yuguang Zheng; Lanfang Wu; Danshen Zhang (Natural Product Research, 2022)

An Investigation of the Effect of Utilizing Solidified Soil as Scour Protection for Offshore Wind Turbine Foundations via a Simplified Scour Resistance Test - Jing Wang; Jinbo Xie; Yingjie Wu; Chen Wang; Fayun Liang (Journal of Marine Science and Engineering, 2022)
Offshore wind power is rapidly developing as a source of clean energy. However, as local scour of the foundation of an offshore wind turbine can create serious safety risks to the normal operation of the turbine, it is necessary to protect the foundation from scour. In this paper, a new scour protection countermeasure using solidified soil has been investigated via an updated apparatus for a simplified scour resistance test (SSRT). Two types of tests were carried out: an unconfined compressive test to determine geotechnical parameters and an SSRT test to reflect the scour resistance of the soil samples. The results show that unconfined strength is approximately related to the critical flow velocity of the scour resistance as a power function. Soil samples having an unconfined compressive strength of 300 kPa can resist erosion under flow conditions above 3.14 m/s after solidification. In addition, the solidification state of the solidified soil has a great impact on the scour resistance of the soil sample, and the critical scour velocity of the final solidified soil is increased by 80–150% as compared to an initial solidified soil having the same final unconfined strength. These results suggest that attention should be paid to the state of the solidified soil during the construction process. The engineers should control the ratio of cement, water, and soil of the solidified soil according to the hydraulic parameters at the time of construction so that no great loss of solidified soil will occur during the construction process.

Molecular Composition of Dissolved Organic Matter in the Changjiang (Yangtze River) – Imprints of Anthropogenic Impact - Ying Wu; Boris P. Koch; Xiaona Wang; Matthias Witt; Xiaolu Wang; Hongyan Bao; Shuchai Gan; Gerhard Kattner; Jing Zhang (Frontiers in Marine Science, 2022)
Understanding the biogeochemical transformation of dissolved organic matter (DOM) across fluvial networks will ultimately help to predict anthropogenic influences. To date, few studies have evaluated the anthropogenic impact on the spatial and temporal changes of DOM composition in large river systems. Here, FT-ICR-MS combined with excitation-emission matrix spectroscopy (EEMs) and biomarkers were applied to resolve chemical differences of DOM collected from the Changjiang basin at different hydrological and environmental conditions. PCA and cluster analysis illustrated that samples collected from lake systems and northern and southern tributaries differed from the two batches of main stream samples, particularly due to higher contribution of nitrogen and sulfur containing compounds. Correlation of land-use information along the tributaries with different PCA loadings indicated that agricultural, forest and wetland areas and wastewater discharge control the composition of DOM within these subregions. Higher heteroatom content (especially CHONx) in the low discharge period (2009) may be contributed by paddy soil leaching into groundwater. The relative peak magnitude of sulfur containing formulas was elevated during flood season (2010), which may be related to pollutions in areas of high population density. In addition, lignin phenol concentrations were higher in the flood season because of elevated soil erosion. Consequently, land use and human activities can strongly alter the quality and composition of DOM in watersheds flowing through densely populated regions, which may also impact or influence the riverine carbon flux in anthropogenically disturbed river systems.

Unraveling environmental drivers of chlorophyll seasonal and interannual variability in the East China Sea - Yi Xu; Ying Wu; Peng Xiu; Jianzhong Ge; Jing Zhang (Frontiers in Marine Science, 2022)
Phytoplankton, the dominant marine primary producers, are considered highly sensitive indicators of ecosystem conditions and changes. The East China Sea (ECS) includes a variety of oceanic and coastal domains that collectively challenge our understanding of phytoplankton dynamics and controls. This study evaluates the seasonal and interannual variability of phytoplankton in the ECS and the underlying environmental determinants based on 22-year satellite chlorophyll (Chl -a ) data and concurrent environmental variables. A seasonal spring bloom was found in the ECS, classically driven by increased stratification, which is associated with increases in sea surface temperature (SST), photosynthetically available radiation (PAR), net heat flux (NHF), and reduced wind mixing. The most significant Chl -a interannual variability was present in a triangular area surrounded by three SST fronts in the southern ECS during springtime. Anomalously high Chl -a (~30% increase) occurred with increased SST and NHF and enhanced wind mixing during negative Pacific Decadal Oscillation (PDO) and El Niño–Southern Oscillation (ENSO) modes. This seems to be contrary to the stratification control model, which fits the seasonal spring bloom observed in this region. More front activities during the negative PDO and ENSO could be associated with Chl -a increase in this triangular area. Contrary to this mixing control scenario, a significant Chl -a increase (~36% increase) also developed during the positive PDO and ENSO modes after 2014 under conditions of higher SST, NHF, and weaker wind mixing following the stratification control scenario. This study used biologically relevant objective regionalization of a heterogeneous area to elucidate phytoplankton bloom dynamics and controls. Our analyses highlight the triangular area in the ECS for its region-specific linkages between Chl -a and multiple climate-sensitive environmental drivers, as well as the potential structural and functional variability in this region.

Effects of Algal Utilization of Dissolved Organic Phosphorus by Microcystis Aeruginosa on Its Adaptation Capability to Ambient Ultraviolet Radiation - Lingxiao Ren; Jing Huang; Huagang Zhu; Wei Jiang; Haoyu Wu; Yuyang Pan; Yinghui Mao; Minghan Luo; Taeseop Jeong (Journal of Marine Science and Engineering, 2022)
Phosphorus (P) plays an important role in eutrophication and algal adaptation to environmental stresses; therefore, a better understanding of the impact of P is essential to control cyanobacterial bloom. In this study, Microcystis aeruginosa is treated with 5 h of ambient irradiation in the culture medium with different availabilities of dissolved organic P (DOP) and dissolved organic matter (DOM) to explore algal physiological responses. Compared to photosynthetically active radiation (PAR), ambient UV-A and UV-B radiation exerted oxidative stresses and has inhibitive effects on the growth and photosynthesis of M. aeruginosa. However, M. aeruginosa had a strong adaptation capability, and the negative effects of UV radiation can be alleviated with DOM addition in the DOP-rich medium. The adaptation of M. aeruginosa to UV radiation in the DOP-rich waters can be mainly achieved through hydrolysis of DOP and metabolism of dissolved inorganic P (DIP), and the DOP utilization behaviors of M. aeruginosa might greatly affect algal UV adaptation capability. In the DOP-rich medium without DOM, the great inactivation of algal alkaline phosphatase (APase) after UV radiation could result in worse affinity for DOP, slower DOP uptake and lower cellular P quota. Consequently, the P demand of M. aeruginosa could not be satisfied for UV adaptation processes, including decreasing UV-induced damages and promoting self-repair. However, DOM could act as an antioxidant and significantly decrease APase inactivation of UV-radiated M. aeruginosa. In the DOP-rich medium with DOM, DOP utilization by M.aeruginosa in the UV-A and UV-B treatments is promoted and algal demand for P is satisfied for its adaptation, such as enhanced production of photosynthetic pigments, increased superoxide dismutase (SOD) activity, recovery of photosynthetic efficiency, etc. Overall, our findings indicate the close relationship between algal DOP utilization and the adaptation to ambient UV radiation of typical cyanobacteria in DIP-limited and DOP-enriched natural waters.

Effect modification by aging on the associations of nicotine exposure with cognitive impairment among Chinese elderly - Jian Hou; Chao Huang; Bo Zhu; Wei Liu; Qing-qing Zhu; Lu Wang; Tian Li; Chun-jie Yuan; Shao-yang Lai; De-sheng Wu; Fei-qi Zhu; Jia-fei Zhang; et al. (Environmental Science and Pollution Research, 2022)

Distinct roles of global cyclonic and anticyclonic eddies in regulating near-inertial internal waves in the ocean interior - Man Yuan; Zhuo Song; Zhao Jing; Zhuoran Li; Lixin Wu (Frontiers in Marine Science, 2022)
In this study, we examine the regulation of wind-powered near-inertial internal waves (NIWs) in the ocean interior by mesoscale eddies, using an eddy-resolving global climate model. There is an enhancement (weakening) of NIW activity within anticyclonic (cyclonic) eddies from the surface boundary layer (SBL) base down to ~4,000 m, associated with a decreased (increased) wave vertical scale. The influence of anticyclonic eddies on NIW activity is more pronounced than that of cyclonic eddies, suggesting that the net effect of mesoscale eddies is to intensify the NIWs in the ocean interior. The enhanced (weakened) NIW activity under the SBL in anticyclonic (cyclonic) eddies is ascribed to both horizontal convergence (divergence) of NIW energy flux under the SBL and increased (decreased) downward NIW energy flux from the SBL base. The former is only confined to a layer within several hundred meters under the SBL, whereas the latter becomes dominant in the deeper ocean.

Genome-wide association study reveals that GhTRL1 and GhPIN8 affect cotton root development - Ziqian Cui; Shaodong Liu; Changwei Ge; Qian Shen; Siping Zhang; Huijuan Ma; Ruihua Liu; Xinhua Zhao; Ruida Liu; Pengzhen Li; Hongchen Wang; Qidi Wu; et al. (Theoretical and Applied Genetics, 2022)

Ticagrelor versus clopidogrel in reducing inflammatory cell infiltration of thrombus aspirated in patients with ST-elevation myocardial infarction - Jing Shen; Guangzhong Liu; Guodong Wu; Lijian Sheng; Zhengyu Cao; Shuyuan Guo; Shaohong Dong; Xin Sun; Ye Tian (European Journal of Clinical Pharmacology, 2022)

Association between the nickel exposure and lipid profiles in general population from NHANES - Ziwei Chen; Jing He; Lihua Chen; Xiaohui Wu; Xiaohong Yu (Environmental Science and Pollution Research, 2022)

Elevated mir-145-5p is associated with skeletal muscle dysfunction and triggers apoptotic cell death in C2C12 myotubes - Jing Jin; Fanyi Li; Caihong Fan; Yu Wu; Chunhui He (Journal of Muscle Research and Cell Motility, 2022)

Monitoring periodically national land use changes and analyzing their spatiotemporal patterns in China during 2015–2020 - Wenhui Kuang; Shuwen Zhang; Guoming Du; Changzhen Yan; Shixin Wu; Rendong Li; Dengsheng Lu; Tao Pan; Jing Ning; Changqing Guo; Jinwei Dong; Yuhai Bao; et al. (Journal of Geographical Sciences, 2022)

Collapse mechanism of deep buried tunnel subjected to pore water pressure with generalized nonlinear unified strength theory - Lingli Xie; Dexin Lei; Jing Wang; Ruibing He; Tiange Qin; Li Wu (Arabian Journal of Geosciences, 2022)

Ancylostoma ceylanicum Infection in a Miniature Schnauzer Dog Breed - Xu-Hui Lin; Hai-Ming Cai; Zhuan-Qiang Yan; Shen-Quan Liao; Min-Na Lv; Cai-Yan Wu; Juan Li; Jun-Jing Hu; Wen-Wan Xiao; Jian-Fei Zhang; Nan-Shan Qi; Ming-Fei Sun (Acta Parasitologica, 2022)

Fermented tea residue improved growth performance, liver antioxidant capacity, intestinal morphology and resistance to Aeromonas hydrophila infection in juvenile largemouth bass (Micropterus salmoides) - Li Jiang; Xinhong Zhou; Jing Yu; Songsong Bao; Jin Li; Qiuhong Wu; Mengjia Wu; Yachao Wang; Bo Liu (Frontiers in Marine Science, 2022)
The study aimed to evaluate the effects of fermented tea residue (FT) on growth performance, intestinal morphology, liver antioxidant capacity and Aeromonas hydrophila infection in juvenile Largemouth bass. A total of 240 fish were randomly distributed in 12 tanks with 20 fish per tank (4 treatments with 3 replications) and fed with diets FT at the rate of 0 (control), 2, 4 and 6%. The weight gain rate (WGR), specific growth rate (SGR) and intestinal villi height (VH) of juvenile largemouth bass were significantly higher than those of the control group after feeding FT (P< 0.05); meanwhile, the liver superoxide dismutase (SOD), glutathione peroxidase (GSH-PX) and catalase (CAT) activities of juvenile largemouth bass were significantly higher and the malondialdehyde (MDA) levels were significantly lower than those of the control group after feeding FT (P< 0.05). Mortality occurred in all groups of largemouth bass after the injection of A.hydrophila , but feeding FT reduced the cumulative mortality compared with the control group (P< 0.05). In juvenile largemouth bass infected with A.hydrophila , the relative mRNA expression of the intestinal anti-inflammatory factors IL-10 and TGF-α was significantly higher and that of the pro-inflammatory factors IL-1, IL-15, IL-8, and TNF-α was significantly lower (P< 0.05). In summary, it can be seen that a 2% FT addition can improve the liver antioxidant capacity of juvenile largemouth bass, enhance the resistance to A.hydrophila and increase the growth of largemouth bass.

Phenoxychromone and 4-hydroxyisoflavans from the roots of Glycyrrhiza uralensis - Zulfiqar Ali; Mohammed Hawwal; Bharathi Avula; Amar G. Chittiboyina; Jing Li; Charles Wu; Ikhlas A. Khan (Natural Product Research, 2022)

Stability Analysis of Surrounding Rock in Underground Chamber Excavation of Coral Reef Limestone - Jing Wu; Hao Fu; Lewen Zhang; Xiangyu Zhang; Deyu Guo (Rock Mechanics and Rock Engineering, 2022)

Neoarchean granitic rocks from the Jiamiao area of the Dabie orogen: Implications on the formation and early evolution of the Yangtze Craton - Yang Tian; Wei Wang; Wei Jin; Yuanbao Wu; Jing Wang; Xin Deng; Sifang Huang (Science China Earth Sciences, 2022)

Functional Investigation of TUBB4A Variants Associated with Different Clinical Phenotypes - Hui Xiao; Hailan He; Tenghui Wu; Xiaoyuan Ni; Fangyun Liu; Fei Yin; Jing Peng (Molecular Neurobiology, 2022)

Phosphatase phoD gene community changes organic phosphorus in sediment from Caohai plateau wetland - Yunchuan Long; Juan Jiang; Bin Wu; Jing Hu; Zhenming Zhang; Shaoqi Zhou (Journal of Soils and Sediments, 2022)

Biochar in Combination with Nitrogen Fertilizer is a Technique: To Enhance Physiological and Morphological Traits of Rice (Oryza sativa L.) by Improving Soil Physio-biochemical Properties - Izhar Ali; Quan Zhao; Ke Wu; Saif Ullah; Anas Iqbal; He Liang; Jing Zhang; Ihsan Muhammad; Amanullah; Abdullah Khan; Asad Ali Khan; Ligeng Jiang (Journal of Plant Growth Regulation, 2022)

Identification of microRNAs related with neural germ layer lineage-specific progenitors during reprogramming - Ruizhen Sun; Tiantian Gong; Hui Liu; Jingling Shen; Bin Wu; Qi Jiang; Qi Wang; Yue Zhang; Lian Duan; Jing Hu; Qiuming Li; Lei Lei; et al. (Journal of Molecular Histology, 2022)

Taxifolin blocks monosodium urate crystal-induced gouty inflammation by regulating phagocytosis and autophagy - Mei-Hua Piao; Hui Wang; Yin-Jing Jiang; Yan-Ling Wu; Ji-Xing Nan; Li-Hua Lian (Inflammopharmacology, 2022)

Prediction of Water Inflow into Tunnel Crossing Intersecting Faults Based on IDB Seepage Model - Jing Wu; Li Wu; Ya-ni Lu; Yan-hua Han; Jun-jie Jiang (Geotechnical and Geological Engineering, 2022)

The monthly variation tendency of microcystin-LR levels in the Huangpu River (China) by applications of ELISA and HPLC - Sijia Hua; Jiawen Chen; Liang Wu; Xinyue Yu; Jing Ye; Yuanting Li; Yongqiang Zhu; Fuxiang Tian (Environmental Science and Pollution Research, 2022)

The drivers of collaborative innovation of the comprehensive utilization technologies of coal fly ash in China: a network analysis - Xiaokun Yu; Yue Cui; Yilin Chen; I-Shin Chang; Jing Wu (Environmental Science and Pollution Research, 2022)

PLXDC2 enhances invadopodium formation to promote invasion and metastasis of gastric cancer cells via interacting with PTP1B - Bin Wu; Yan-xia Wang; Jun-jie Wang; Dong-fang Xiang; Meng-si Zhang; Ze-xuan Yan; Wen-ying Wang; Jing-ya Miao; Xi Lan; Jia-jia Liu; Zheng-yan Li; Chuan Li; et al. (Clinical & Experimental Metastasis, 2022)
Plexin-domain containing 2 (PLXDC2) has been reported as an oncoprotein in several human malignancies. However, its expression and roles in gastric cancer remain largely unclear. In this study, we found that PLXDC2 was highly expressed in gastric cancer tissues, and the expression levels were positively correlated with clinicopathological features, but negatively with the patients’ outcome. Cox regression analysis identified PLXDC2 as an independent prognostic indicator for the patients. Knockdown of PLXDC2 markedly suppressed the in vitro invasion and in vivo metastasis of gastric cancer cells, while overexpression of PLXDC2 resulted in opposite effects. Mechanistically, PLXDC2 enhanced the level of phosphorylated Cortactin (p-Cortactin) by physically interacting with protein tyrosine phosphatase 1B (PTP1B), an important dephosphorylase, to prevent its dephosphorylating of p-Cortactin, thereby promoting the formation of invadopodia. Collectively, our results indicate that PLXDC2 contributes to the invasion and metastasis of gastric cancer by inhibiting PTP1B to facilitate the invadopodium formation, and may serve as a potential prognostic biomarker and a therapeutic target for this disease.

Disruption of regional homogeneity in the brains of chronic methamphetamine users - Lili Nie; Xiantao Wen; Wei Luo; Tao Ju; Anlian Ren; Binbin Wu; Jing Li; Jinsheng Hu (Brain Imaging and Behavior, 2022)

Occurrence Characteristics of Saline-Lacustrine Shale-Oil in the Qianjiang Depression, Jianghan Basin, Central China - Zhongliang Sun; Zhiliang He; Furong Wang; Yuanjia Han; Sheng He; Yuguang Hou; Jing Luo; Youheng Zheng; Shiqiang Wu (Journal of Earth Science, 2022)

Research on the morphological characteristics and the sequence determination method of the collapse of combined rock strata structures - Jianyang Yu; Hao Wu; Hongdi Jing; Xiaobo Liu; Liancheng Wang (Arabian Journal of Geosciences, 2022)

Association of ATG5 gene polymorphism with Parkinson’s disease in a Han Chinese population - Jing Han; Ganghua Feng; Jibao Wu; Yi Zhang; Zhipeng Long; Xiaoxi Yao (Acta Neurologica Belgica, 2022)
Purpose There is growing evidence that autophagy-related gene 5 (ATG5) is involved in neural development, neuronal differentiation, and neurodegenerative diseases. The purpose of this study was to investigate the association between ATG5 gene single-nucleotide polymorphisms (SNPs) and Parkinson’s disease (PD) in the Han population. Methods A case–control study was conducted in 120 PD patients and 100 healthy volunteers. MassArray platform was used to analyze polymorphisms in three different regions of ATG5 gene (rs510432, rs573775 and rs17587319). In the included subjects, 50 PD patients and 50 healthy volunteers were selected, and the plasma ATG5 concentration was detected by enzyme-linked immunosorbent assay (ELISA). The allele and genotype frequencies of SNPs were assessed using the SHEsis program. Results We found a significant correlation between rs17587319 and PD, and the subcomponent showed a high correlation between rs17587319 with cognitive impairment and age at onset in PD patients. At the same time, the total plasma ATG5 level of PD patients and the plasma ATG5 expression level of early-onset Parkinson’s disease (EOPD) patients were significantly higher than the control group, while there was no significant difference of ATG5 expression between late-onset Parkinson’s disease (LOPD) patients and the control group. Conclusion These findings suggest that genetic variations in the ATG5 gene and low levels of the ATG5 protein are associated with susceptibility to PD and with cognitive impairment in PD patients. ATG5 could be a potential biomarker to assess the severity and prognosis of PD.

Soil moisture regulates warming responses of autumn photosynthetic transition dates in subtropical forests - Yongshuo H. Fu; Xinxi Li; Shouzhi Chen; Zhaofei Wu; Jianrong Su; Xing Li; Shuaifeng Li; Jing Zhang; Jing Tang; Jingfeng Xiao (Global Change Biology, 2022)
Autumn phenology plays a key role in regulating the terrestrial carbon and water balance and their feedbacks to the climate. However, the mechanisms underlying autumn phenology are still poorly understood, especially in subtropical forests. In this study, we extracted the autumn photosynthetic transition dates (APTD) in subtropical China over the period 2003–2017 based on a global, fine‐resolution solar‐induced chlorophyll fluorescence (SIF) dataset (GOSIF) using four fitting methods, and then explored the temporal–spatial variations of APTD and its underlying mechanisms using partial correlation analysis and machine learning methods. We further predicted the APTD shifts under future climate warming conditions by applying process‐based and machine learning‐based models. We found that the APTD was significantly delayed, with an average rate of 7.7 days per decade, in subtropical China during 2003–2017. Both partial correlation analysis and machine learning methods revealed that soil moisture was the primary driver responsible for the APTD changes in southern subtropical monsoon evergreen forest (SEF) and middle subtropical evergreen forest (MEF), whereas solar radiation controlled the APTD variations in the northern evergreen‐broadleaf deciduous mixed forest (NMF). Combining the effects of temperature, soil moisture and radiation, we found a significantly delayed trend in APTD during the 2030–2100 period, but the trend amplitude (0.8 days per decade) was much weaker than that over 2003–2017. In addition, we found that machine learning methods outperformed process‐based models in projecting APTD. Our findings generate from different methods highlight that soil moisture is one of the key players in determining autumn photosynthetic phenological processes in subtropical forests. To comprehensively understand autumn phenological processes, in‐situ manipulative experiments are urgently needed to quantify the contributions of different environmental and physiological factors in regulating plants' response to ongoing climate change.

Vertical patterns of chlorophyll a in the euphotic layer are related to mesoscale eddies in the South China Sea - Mei-Lin Wu; You-Shao Wang; Yu-Tu Wang; Fu-Lin Sun; Xiaomei Li; Fang-Fang Gu; Jing-Chang Xiang (Frontiers in Marine Science, 2022)
Phytoplankton closely connects with the hydrodynamics and biogeochemical environment of the ocean. While research focusing on both the physiochemical factors and hydrodynamics regulating phytoplankton has already been conducted, the coupling mechanism between mesoscale eddies and the vertical distribution of phyto plankton in the South China Sea (SCS) is still not well understood. Here, phytoplankton was studied under one weak-cold and two warm eddies along the 18°N transect in the SCS. The results show that the vertical distribution of chlorophyll (chl- a ) presented a similar pattern at all four sampling stations. The mixed layer is less than 50 m. It is the same as the meridional salinity gradients that may be distinguished above a depth of 60 m. The subsurface chlorophyll maximum at the edge of a warm (WI) and cold eddy (CI) at E413 and E411 was shallower than that at the edge of a warm eddy (WII) at E407 and E409, indicating that temperature and salinity may be the important driving factors. On the whole, mesoscale eddies had a significant influence on the vertical pattern of chl- a in the SCS during the study period.

Metatranscriptomic analysis of host response and vaginal microbiome of patients with severe COVID-19 - Meng Xiao; Bo Lu; Rui Ding; Xia Liu; Xian Wu; Yaqian Li; Xudong Liu; Lin Qiu; Zhibo Zhang; Jing Xie; Yu Chen; Dong Zhang; et al. (Science China Life Sciences, 2022)

Lithospheric structure beneath Ordos Block and surrounding areas from joint inversion of receiver function and surface wave dispersion - Jianping Wu; Yaning Liu; Shijun Zhong; Weilai Wang; Yan Cai; Wei Wang; Jing Liu (Science China Earth Sciences, 2022)

Novel acetylation-related gene signatures for predicting the prognosis of patients with colorectal cancer - Zhuang Jing; Feng Ziwang; Wu Yinhang; Zhou Yani; Chu Jian; Wu Jingwen; Han Shuwen (Human Cell, 2022)

Pharmacokinetics of benapenem for injection in subjects with mild to moderate renal impairment - Haijing Yang; Min Zhang; Yuancheng Chen; Hong Ren; Hong Zhang; Chen Yu; Jianda Lu; Li You; Jicheng Yu; Hong Liang; Cuilan Xiao; Zishuang He; et al. (European Journal of Clinical Pharmacology, 2022)

Betulinic acid attenuates cognitive dysfunction, oxidative stress, and inflammation in a model of T-2 toxin-induced brain damage - You Huang; Zihan Zhu; Chenxi Luo; Chaoyang Ma; Lijuan Zhu; Li Kong; Rongfang Li; Jing Wu; Zhihang Yuan; Jine Yi (Environmental Science and Pollution Research, 2022)

Effects of shining pondweed (Potamogeton lucens) on bacterial communities in water and rhizosphere sediments in Nansi Lake, China - Nianxin Zhang; Mengmeng Wu; Yuying Che; Yong Kong; Fengyue Shu; Qingfeng Wang; Weilai Sha; Zhijin Gong; Jing Zhou (Environmental Science and Pollution Research, 2022)

Spatial Characteristics and Risk Assessment of Heavy Metals in the Soil-Vegetation System of a Red Mud Slag Yard, SW China - Runyu Zhang; Zhi Zhang; Jing Wu; Liying Wang (Bulletin of Environmental Contamination and Toxicology, 2022)

Probabilistic stability analysis of tunnel roof in two-layer soil mass combining upper bound theorem and response surface method - Dexin Lei; Lingli Xie; Jing Wang; Li Wu (Arabian Journal of Geosciences, 2022)

Remarkable effects of microbial factors on soil phosphorus bioavailability: A country‐scale study - Jing‐li Lu; Pu Jia; Shi‐wei Feng; Yu‐tao Wang; Jin Zheng; Shu‐ning Ou; Zhuo‐hui Wu; Bin Liao; Wen‐sheng Shu; Jie‐Liang Liang; Jin‐tian Li (Global Change Biology, 2022)
Low soil phosphorus (P) bioavailability causes the widespread occurrence of P‐limited terrestrial ecosystems around the globe. Exploring the factors influencing soil P bioavailability at large spatial scales is critical for managing these ecosystems. However, previous studies have mostly focused on abiotic factors. In this study, we explored the effects of microbial factors on soil P bioavailability of terrestrial ecosystems using a country‐scale sampling effort. Our results showed that soil microbial biomass carbon (MBC) and acid phosphatase were important predictors of soil P bioavailability of agro‐ and natural ecosystems across China although they appeared less important than total soil P. The two microbial factors had a positive effect on soil P bioavailability of both ecosystem types and were able to mediate the effects of several abiotic factors (e.g., mean annual temperature). Meanwhile, we revealed that soil phytase could affect soil P bioavailability at the country scale via ways similar to those of soil MBC and acid phosphatase, a pattern being more pronounced in agroecosystems than in natural ecosystems. Moreover, we obtained evidence for the positive effects of microbial genes encoding these enzymes on soil P bioavailability at the country scale although their effect sizes varied between the two ecosystem types. Taken together, this study demonstrated the remarkable effects of microbial factors on soil P bioavailability at a large spatial scale, highlighting the importance to consider microbial factors in managing the widespread P‐limited terrestrial ecosystems.

Evaluation of a Causative Species of Harmful Algal Blooming, Prorocentrum triestinum, as a Sustainable Source of Biosorption on Cadmium - Steven Jing-Liang Xu; Kam-Chau Wu; Winnie Lam; Fred Wang-Fat Lee (Journal of Marine Science and Engineering, 2022)
Biosorption is an effective method for removing heavy metal ions from wastewater. In the current study, the biosorption capacity of a microalgae Prorocentrum triestinum strain AD1 was investigated for cadmium removal. The efficient biomass concentration was found to be 5 g/L. Based on the Langmuir adsorption model, the maximum adsorption capacity (qmax) value of cadmium removal was found to be 0.0196 mmol/g. The investigation results of the AD1 biosorption kinetics showed that the effective contact time on biosorption was 3 h, and the adsorption kinetics fitted well with the pseudo-second-order model. The optimum pH of biosorption was found to be 5. On the other hand, HCl could act as an efficient desorbent for cadmium recovery from AD1, with an optimum concentration of 0.01 M. These results suggest that the biomass of P. triestinum has great potential for the removal of cadmium from wastewater as an efficient biosorbent.

Legacy effect of extreme wetness events on subsequent tree growth evidenced by water use source shifts in a semi-arid region of North China - Yuanqiao Li; Yingping Pan; Xiaoyan Li; Jing Zhao; Fangzhong Shi; Xiuchen Wu; Yongmei Huang (Trees, 2022)

A superior allele of the wheat gene TaGL3.3-5B, selected in the breeding process, contributes to seed size and weight - Chaojie Wang; Lili Zhang; Yongdun Xie; Xiaofeng Guo; Yanfang Zhang; Yamin Zhang; Ahsan Irshad; Yuting Li; Huihui Qian; Doudou Jing; Guangyao Liu; Kaiming Wu; et al. (Theoretical and Applied Genetics, 2022)

Evolutionary history of post-fire debris flows in Ren’e Yong valley in Sichuan Province of China - Yan Wang; Xiewen Hu; Lijun Wu; Guotao Ma; Ying Yang; Tao Jing (Landslides, 2022)

Dynamic response relationship between cultivated land marginalisation and rural labour out-migration in mountainous areas in China: evidence from a vector autoregressive model - Jingwei Xiang; Wanxu Chen; Jing Wu (Environmental Science and Pollution Research, 2022)

Changes in carbon emission performance of energy-intensive industries in China - Yao Chen; Jing Wu (Environmental Science and Pollution Research, 2022)

Production of phenylpyruvic acid by engineered l-amino acid deaminase from Proteus mirabilis - Jia Liu; Jianmin Liu; Bin Yang; Cong Gao; Wei Song; Guipeng Hu; Liming Liu; Jing Wu (Biotechnology Letters, 2022)

Brain structural and functional anomalies associated with simultanagnosia in patients with posterior cortical atrophy - Yue Cui; Yang Liu; Caishui Yang; Chunlei Cui; Donglai Jing; Xuxiang Zhang; Yaojing Chen; Bingkun Li; Zhigang Liang; Kewei Chen; Zhanjun Zhang; Liyong Wu (Brain Imaging and Behavior, 2022)
Simultanagnosia is a common symptom of posterior cortical atrophy, and its association with brain structural and functional changes remains unclear. In our study, 18 posterior cortical atrophy patients with simultanagnosia, 29 patients with Alzheimer’s disease and 20 cognitively normal controls were recruited and subjected to full neuropsychological evaluation, including simultanagnosia tests, and structural and resting-state functional MRI. The gray matter volume was assessed by voxel-based morphometry, while the intrinsic functional connectivity was evaluated using the reduced gray matter volume regions of interest as the seed. In contrast to the patients with Alzheimer’s disease, those with posterior cortical atrophy showed the following: (1) markedly lower simultanagnosia test scores, (2) an altered regional gray matter volume of the left middle occipital gyrus and ventral occipital areas, and (3) lowered intrinsic functional connectivity with the left middle occipital gyrus, left lingual gyrus and right middle occipital gyrus separately. Additionally, the gray matter volume of the left middle occipital gyrus and left inferior occipital gyrus were each correlated with simultanagnosia in posterior cortical atrophy patients. The intrinsic functional connectivity of the left middle occipital gyrus with the right superior occipital gyrus and that of the right middle occipital gyrus with the left superior parietal gyrus were also correlated with simultanagnosia in posterior cortical atrophy patients. In summary, this study indicated that simultanagnosia is associated with gray matter reductions and decreased functional connectivity in the left middle occipital gyrus and the left inferior occipital gyrus in patients with posterior cortical atrophy.

Investigating the effect of compaction on the anaerobic digestion process of rice straw - Guang-Yin Chen; Hai-Nan Cao; Xue-Qian Fan; Yi-Chen Sun; Jing Wang; Jin-Zhu Dong; Pei Wu (BioEnergy Research, 2022)

Liver transcriptome analyses of acute poisoning and recovery of male ICR mice exposed to the mushroom toxin α-amanitin - Zhijun Wu; Haijiao Li; Yizhe Zhang; Chunguang Ding; Wenjin Zhao; Jing Dai; Chengmin Yu; Qunmei Yao; Fenshuang Zheng; Jingguang Fan; Chengye Sun (Archives of Toxicology, 2022)

Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway - Tianwei Zhang; Shanshan Feng; Jiahuan Li; Zhitao Wu; Qiangqiang Deng; Wei Yang; Jing Li; Guoyu Pan (Archives of Toxicology, 2022)

A newly isolated human intestinal strain deglycosylating flavonoid C-glycosides - Sha Wang; Siqi Liu; Jing Wang; Jiayue Tao; Mengjiao Wu; Wenfu Ma; Rufeng Wang (Archives of Microbiology, 2022)

A patchy-saturated rock physics model for tight sandstone based on microscopic pore structures - Chun-Fang Wu; Jing Ba; José M. Carcione; Tobias M. Müller; Lin Zhang (Applied Geophysics, 2022)

Expanding the clinical spectrum of adult-onset neuronal intranuclear inclusion disease - Yuwen Cao; Jingying Wu; Yunhua Yue; Chao Zhang; Shihua Liu; Ping Zhong; Shige Wang; Xiaojun Huang; Weiping Deng; Jing Pan; Lan Zheng; Qing Liu; et al. (Acta Neurologica Belgica, 2022)

Implication of Macroalgal Bloom to Soil Organic Carbon Stock in Seagrass Meadows - A Case Study in South Hainan, China - Shunyang Chen; Shiquan Chen; Bin Chen; Zhongjie Wu; Wenshuo An; Lizhen Luo; Jing Wang; Limei Xie; Jing Zhang; Guangcheng Chen (Frontiers in Marine Science, 2022)
The adverse impact of macroalgal blooms associated with nutrient enrichment on seagrass habitats and carbon storage potential is an ecological concern. In the present study, the soil carbon stock and sources were compared between a seagrass meadow where a serious macroalgal bloom occurred (site M) and an adjacent site without apparent macroalgae (site R) in a nutrient-enriched lagoon in South Hainan Island, China, to test whether macroalgal blooms associated with nutrient enrichment would impact the soil carbon in seagrass meadows. The soil organic carbon (OC) and total nitrogen contents in the top 30 cm at site M were significantly lower than those at site R. The soil OC stocks (top 30 cm) were 3.4 and 5.4 Mg C ha -1 at site M and site R, respectively, and no difference was observed between sampling stations with different distances offshore at either site. Soil δ 13 C was more enriched and closer to the δ 13 C of seagrass tissues at site R than at site M. Bayesian stable isotope mixing model analyses suggested that seagrass-derived material contributed ~50% to soil OC at site R, while at site M, the contribution was reduced to ~25%. The results suggested that macroalgal blooms associated with nutrient enrichment could drive the loss of seagrass-derived OC and the OC stock in the soil, which is worthy of full attention for blue carbon conservation.

How do precipitation events modify the stable isotope ratios in leaf water at Lhasa on the southern Tibetan Plateau? - Yong Wang; Wusheng Yu; Lun Luo; Minghui Li; Xiaoming Liu; Rong Guo; Yaoming Ma; Baiqing Xu; Guangjan Wu; Chengyi Zhao; Zhaowei Jing; Feili Wei; et al. (Isotopes in Environmental and Health Studies, 2022)

Diverse Responses of Phenology in Multi-Grassland to Environmental Factors on Qinghai–Tibetan Plateau in China - Gexia Qin; Benjamin Adu; Chunbin Li; Jing Wu (Theoretical and Applied Climatology, 2022)

Proteomic characterization of four subtypes of M2 macrophages derived from human THP-1 cells - Pengfei Li; Chen Ma; Jing Li; Shanshan You; Liuyi Dang; Jingyu Wu; Zhifang Hao; Jun Li; Yuan Zhi; Lin Chen; Shisheng Sun (Journal of Zhejiang University-SCIENCE B, 2022)

First report of Capsicum frutescens endornavirus 1 infecting pepper in China - Ming-xia Gong; Hu Zhao; Xing Wu; Meng Wang; Zeng-jing Zhao; Zhi He; Ru-kui Huang; Jing-ping Sun; Ri-sheng Wang (Journal of Plant Pathology, 2022)

First report of plum bark necrosis stem pitting-associated virus affecting sweet cherry in Yunnan, China - Miao Guo; Jing Zhong; Chaowen Wang; Yue Chen; Zhengsong Yang; Tingting Li; Yongbin Wu; Yongqing Mu; Ming Ding; Jiawei He (Journal of Plant Pathology, 2022)

Influence of persulfate on transformation of phosphorus and heavy metals for improving sewage sludge dewaterability by hydrothermal treatment - Qiao Xiong; Jing Xia; Xiang Wu; Xu Wu; Haobo Hou; Hang Lv (Environmental Science and Pollution Research, 2022)

Mixed effects of perfluoroalkyl and polyfluoroalkyl substances exposure on cognitive function among people over 60 years old from NHANES - Xueqiong Weng; Huanzhu Liang; Yuxuan Tan; Jingmin Chen; Qiaoyuan Fei; Shan Liu; Xinrong Guo; Lin Wen; Yingying Wu; Chunxia Jing (Environmental Science and Pollution Research, 2022)

High-resolution inventory of emissions of atmospheric PM10 from agricultural tillage and harvesting operations in China: historical trend, spatio-temporality, and optimization methodology - Jing Fu; Ruimin Li; Xuewei Wu; Mengduo Zhang; Weiwei Chen; Daniel Tong (Air Quality, Atmosphere & Health, 2022)

Fast and sensitive graphene oxide‐DNAzyme‐based biosensor for Vibrio alginolyticus detection - Xueqing Tian; Jinfei Hu; Tong Wei; Wen Ding; Qingzhen Miao; Zhe Ning; Shihui Fan; Hangjie Wu; Jing Lu; Mingsheng Lyu; Shujun Wang (Journal of Fish Diseases, 2022)
DNAzymes have been widely and effectively used for the detection of pathogenic bacteria, which pose a serious public health threat. However, the rapid and cost‐effective detection of such bacteria remains a major challenge. In this study, we successfully selected Vibrio alginolyticus ‐specific DNAzymes. The activity of the candidates was assessed via fluorescence intensity and gel electrophoresis. The DNAzyme DT1 had a detection limit of 31 CFU/ml for V. alginolyticus and exhibited high specificity. Graphene oxide (GO) was used to develop a DNAzyme‐based fluorescent sensor for the detection of V. alginolyticus , which significantly improved detection performance and shortened the reaction time as little as 10 s. The proposed method was then validated using crab, shrimp, fish, clam, and oyster samples. This study thus provides a new method for the rapid and sensitive detection of V. alginolyticus .

Hydraulic Capture Optimization and Risk Assessment of Polluted Groundwater Based on Kriging Surrogate Model - Shuangsheng Zhang; Jing Qiang; Hanhu Liu; Hongli Lv; Jingwen Wu; Junjie Zhou (Water, Air, & Soil Pollution, 2022)

Delayed rFGF21 Administration Improves Cerebrovascular Remodeling and White Matter Repair After Focal Stroke in Diabetic Mice - Yinghua Jiang; Jinrui Han; Yadan Li; Yinga Wu; Ning Liu; Samuel X. Shi; Li Lin; Jing Yuan; Shusheng Wang; Ming-Ming Ning; Aaron S. Dumont; Xiaoying Wang (Translational Stroke Research, 2022)

Contrasting responses of plant above and belowground biomass carbon pools to extreme drought in six grasslands spanning an aridity gradient - Md. Shahariar Jaman; Honghui Wu; Qiang Yu; Qiqi Tan; Yunlong Zhang; Quoc Khanh Dam; Taofeek O. Muraina; Chong Xu; Minghui Jing; Xiaotong Jia; Jie Wang; Nianpeng He; et al. (Plant and Soil, 2022)

Microtubules play a crucial role in regulating actin organization and cell initiation in cotton fibers - Jianyan Zeng; Jing Xi; Baoxia Li; Xingying Yan; Yonglu Dai; Yiping Wu; Yuehua Xiao; Yan Pei; Mi Zhang (Plant Cell Reports, 2022)

Positron Emission Tomography Molecular Imaging for Phenotyping and Management of Lymphoma - Xiaohui Zhang; Han Jiang; Shuang Wu; Jing Wang; Rui Zhou; Xuexin He; Shufang Qian; Shuilin Zhao; Hong Zhang; Ali Cahid Civelek; Mei Tian (Phenomics, 2022)

HIF-1α aggravates pathologic myopia through the miR-150-5p/LAMA4/p38 MAPK signaling axis - Yalin Ren; Xiaobo Yang; Zhi Luo; Jing Wu; Haiyan Lin (Molecular and Cellular Biochemistry, 2022)

Synthesis and anticancer activity of Boc-Gly-Pro dipeptide-annonaceous acetogenin prodrugs targeting fibroblast activation protein or other hydrolytic enzymes - Jing-Fang Shi; Ping Wu; Han-Xiang Li; Xiao-Yi Wei; Zi-Hua Jiang (Medicinal Chemistry Research, 2022)

Measurement of atmospheric conductivity on the Qinghai-Tibet Plateau in China - Lei Li; Jianfeng Su; Tao Chen; Shuo Ti; Han Wu; Jing Luo; Wen Li; Renkang Li (Meteorology and Atmospheric Physics, 2022)

Herbicidal activity and differential metabolism of lactofen in rat and loach on an enantiomeric level - Fang Wang; Jing Gao; Peize Li; Shanxue Jiang; Junxue Wu; Zhiliang Yao (Environmental Science and Pollution Research, 2022)

Mechanical property and microstructure of cemented tailings backfill containing fly ash activated by calcium formate - Yiming Wang; Jiangyu Wu; Hai Pu; Qian Yin; Hongwen Jing (Environmental Science and Pollution Research, 2022)

The altered functional modular organization in systemic lupus erythematosus: an independent component analysis study - Zheng-Ye Cao; Na Wang; Hua Wei; Jie-Ting Jia; Hong-Ying Zhang; Song-An Shang; Qing-Qiang Zhu; Xian-Fu Luo; Jing-Tao Wu (Brain Imaging and Behavior, 2022)

Isolation, Identification, and Quantitative Determination of Saponin in Apostichopus japonicus by HPLC-DAD - Guiying Liu; Xuda Wang; Kun Ge; Jinhao Wu; Zhaohui Wang; Jing Du; Lun Song; Zunchun Zhou (Journal of Ocean University of China, 2022)

Evolutionary analysis of a newly isolated Banna virus strain from Yunnan, China - Jianfang Li; Xiaofang Guo; Yanhan Li; Ningzhu Hu; Jing Sun; Meini Wu; Hongning Zhou; Yunzhang Hu (Archives of Virology, 2022)

Future changes in the meteorological potential for winter haze over Beijing during periods of peak carbon emissions and carbon neutrality in China projected by Coupled Model Intercomparison Project Phase 6 models - Jing Wang; Yanju Liu; Yihui Ding; Yang Yang; Ying Xu; Qiaoping Li; Yingxian Zhang; Meng Gao; Jianbo Yang; Qingyuan Wu; Chunhui Li; Mingcai Li (International Journal of Climatology, 2022)
Hazy conditions have a significant impact on the environment and societal development. Their occurrence and persistence depend largely on climatological conditions, including the important role of climate change. Based on monthly data from 15 Coupled Model Intercomparison Project Phase 6 (CMIP6) models under three Tier 1 scenarios (SSP1–2.6, SSP2–4.5, and SSP5–8.5), the meteorological potential for winter haze pollution over Beijing was assessed during periods of peak carbon emissions (P CP ; 2021–2030) and carbon neutrality (approximate net‐zero emissions) (P CN ; 2051–2060) in China. The results show that a possible high‐emission strategy during P CP may not obviously enhance winter hazy conditions over Beijing in the near future. Rather, the high‐emission scenario in this period may decrease the meteorological potential that is favourable for the enhanced Beijing haze pollution by inducing a Northeast Asia cyclonic anomaly, compared to situations under SSP2–4.5, with medium emissions. Further analyses indicated that, under the continued sustainable pathway (SSP1–2.6 in P CN plus SSP1–2.6 in P CP ; the better pathway simulating the effects of approximate net‐zero emissions during P CN through model results), atmospheric conditions such as the East Asian winter monsoon as well as decadal oceanic forcings of the mega‐El Niño and the warm Atlantic Multidecadal Oscillation, which are conducive to more frequent Beijing haze, are significantly suppressed in the farther future P CN . Under such circumstances, in situ haze pollution is highly repressed, suggesting a critical and positive role for the low‐carbon policy advocated by China during P CN in suppressing longer‐term hazy conditions over Beijing. In contrast, Beijing haze pollution during P CN is frequent under the discontinued sustainable pathway (SSP2–4.5/SSP5–8.5 in P CN plus SSP1–2.6 in P CP ). Our findings demonstrate the possible insignificant impact of the high‐emission strategy of China during the near‐future P CP on Beijing haze exacerbation, and an important role for carbon neutrality advocated by China to suppress the haze potential in the farther future P CN , highlighting the significance of future pathway selections.

Development of MEMS directed evolution strategy for multiplied throughput and convergent evolution of cytochrome P450 enzymes - Li Ma; Fengwei Li; Xingwang Zhang; Hui Chen; Qian Huang; Jing Su; Xiaohui Liu; Tianjian Sun; Bo Fang; Kun Liu; Dandan Tang; Dalei Wu; et al. (Science China Life Sciences, 2022)

Hippocampal SIRT1-Mediated Synaptic Plasticity and Glutamatergic Neuronal Excitability Are Involved in Prolonged Cognitive Dysfunction of Neonatal Rats Exposed to Propofol - Lin-Hui Ma; Jie Wan; Jing Yan; Ning Wang; Yan-Ping Liu; Hai-Bi Wang; Cheng-Hua Zhou; Yu-Qing Wu (Molecular Neurobiology, 2022)

Activating PIK3CA postzygotic mutations in segmental overgrowth of muscles with bone involvement in the body extremities - Wen Tian; Liying Sun; Qi Zhang; Junhui Zhao; Yang Guo; Wenyao Zhong; Liu Liu; Katia Meirelles; Sha Tang; Jing Zhang; Yingzhao Huang; Yuehan Yin; et al. (Molecular Genetics and Genomics, 2022)

Development of Simple Sequence Repeat Markers from Functional Genes and Establishment of Molecular Identity for Tree Peony - Cheng Li; Jing Wu; Qingdao Li; Yunyao Yang; Kezhong Zhang (Journal of Plant Biochemistry and Biotechnology, 2022)

USP36 promotes tumor growth of non-small cell lung cancer via increasing KHK-A expression by regulating c-MYC–hnRNPH1/H2 axis - Qian Deng; Maolin Wu; Jing Deng (Human Cell, 2022)

Analysis and Research on Blasting Network Delay of Deep-Buried Diversion Tunnel Crossing Fault Zone Based on EP-CEEMDAN-INHT - Jing Wu; Li Wu; Miao Sun; Ya-ni Lu; Yan-hua Han (Geotechnical and Geological Engineering, 2022)

QTL mapping integrated with BSA-Seq analysis identifies a novel gene conferring resistance to brown planthopper from common wild rice (Oryza rufipogon Griff.) - Xuan Wang; Yue Han; Yue-xiong Zhang; Biao Deng; Bi-qiu Wu; Xin-ying Guo; Yu-fen Qin; Yao-yu Fang; Fang Liu; Bao-xiang Qin; Ji-jing Luo; Rong-bai Li (Euphytica, 2022)

Association between maternal exposure to PM10 and risk of anorectal atresia/stenosis in offspring: a population-based case-control study in Liaoning Province, China - Tie-Ning Zhang; Qi-Jun Wu; Yan-Hong Huang; Jing Li; Zong-Jiao Chen; Li-Li Li; Yan-Ling Chen; Shu Liu; Cheng-Zhi Jiang; Yu-Hong Zhao (Environmental Science and Pollution Research, 2022)

Testing the impact of first-mover advantage on household energy-related carbon emissions: an exploratory study from six urban agglomerations in China - Jingjing Zeng; Li Xu; Jiansheng Qu; Jinyu Han; Jinjia Wu; Jing Bai; Hengji Li (Environmental Science and Pollution Research, 2022)

The total factor productivity index of freshwater aquaculture in China: based on regional heterogeneity - Shen Zhong; Aizhi Li; Jing Wu (Environmental Science and Pollution Research, 2022)

Numerical simulation of water inrush in a tunnel crossing faults: impacts of fault width, damage zone width, and fault permeability - Jing Wu; Xintong Wang; Li Wu; Ya-ni Lu; Yan-hua Han (Arabian Journal of Geosciences, 2022)

MoOpy2 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae - Ying‐Ying Cai; Jing‐Yi Wang; Xi‐Yu Wu; Shuang Liang; Xue‐Ming Zhu; Lin Li; Jian‐Ping Lu; Xiao‐Hong Liu; Fu‐Cheng Lin (Environmental Microbiology, 2022)
Summary The development and pathogenicity of the fungus Magnaporthe oryzae , the causal agent of destructive rice blast disease, require it to perceive external environmental signals. Opy2, an overproduction‐induced pheromone‐resistant protein 2, is a crucial protein for sensing external signals in Saccharomyces cerevisiae . However, the biological functions of the homologue of Opy2 in M. oryzae are unclear. In this study, we identified that MoOPY2 is involved in fungal development, pathogenicity, and autophagy in M. oryzae . Deletion of MoOPY2 resulted in pleiotropic defects in hyphal growth, conidiation, germ tube extension, appressorium formation, appressorium turgor generation, and invasive growth, therefore leading to attenuated pathogenicity. Furthermore, MoOpy2 participates in the Osm1 MAPK pathway and the Mps1 MAPK pathway by interacting with the adaptor protein Mst50. The interaction sites of Mst50 and MoOpy2 colocalized with the autophagic marker protein MoAtg8 in the preautophagosomal structure sites (PAS). Notably, the Δ Moopy2 mutant caused cumulative MoAtg8 lipidation and rapid GFP‐MoAtg8 degradation in response to nitrogen starvation, showing that MoOpy2 is involved in the negative regulation of autophagy activity. Taken together, our study revealed that MoOpy2 of M. oryzae plays an essential role in the orchestration of fungal development, appressorium penetration, autophagy and pathogenesis.

Four new prenylflavonol glycosides from the leaves of Cyclocarya paliurus - Zi-Jun Ye; Hui-Hui Sun; Zu-Hui Chen; Jian-Ping Wu; Jing Li; Hui Zhu; Lu-Lu Huang; Xi-Wen Chang; Sai-Yu Ou; Wen-Xuan Wang; Xiao-Ai He; Gang-Zhi Zhu; et al. (Natural Product Research, 2022)

Incomplete genome doubling enables to consistently enhance plant growth for maximum biomass production by altering multiple transcript co-expression networks in potato - Kanglu Zhao; Nengzhou Jin; Meysam Madadi; Youmei Wang; Lei Wu; Zhijun Xu; Jinxuan Wang; Jing Dong; Shang-wen Tang; Yanting Wang; Liangcai Peng; Zhiyong Xiong (Theoretical and Applied Genetics, 2022)

The aquaporin gene PvXIP1;2 conferring drought resistance identified by GWAS at seedling stage in common bean - Lei Wu; Yujie Chang; Lanfen Wang; Shumin Wang; Jing Wu (Theoretical and Applied Genetics, 2022)

Comparatively analyzing the liver-specific transcriptomic profiles in Kunming mice afflicted with streptozotocin- and natural food-induced type 2 diabetes mellitus - Yanjun Wu; Xiangxing Zhu; Arome Solomon Odiba; Zisheng Lin; Jiancong Wen; Daoyuan Gong; Jing Liang; Shuguang Wu; Ganqiu Lan (Molecular Biology Reports, 2022)

Cellular metabolic basis of altered immunity in the lungs of patients with COVID-19 - Shuangyan Li; Fuxiaonan Zhao; Jing Ye; Kuan Li; Qi Wang; Zhongchao Du; Qing Yue; Sisi Wang; Qi Wu; Huaiyong Chen (Medical Microbiology and Immunology, 2022)

Effects of H2SO4 and Gibberellin A3 on Dormancy Release of Tilia miqueliana Seeds - Yu Wu; Wen Qin Bao; Hui Hu; Ya Jing Zhou; Yong Bao Shen (Journal of Plant Growth Regulation, 2022)

The effect of methyltestosterone (MT) on sex differentiation and growth in juvenile yellow perch (Perca flavescens) - Rafidah Othman; Xiao-Jun Ron; Hong Yao; Paul O’Bryant; Dean Rapp; Jing-Chen Pei; Hong-Juan Wu; Han-Ping Wang (Fish Physiology and Biochemistry, 2022)

Climate change drives NDVI variations at multiple spatiotemporal levels rather than human disturbance in Northwest China - Jiaxin Shang; Yang Zhang; Yu Peng; Yihang Huang; Lu Zhu; Zhuoyi Wu; Jing Wang; Yixin Cui (Environmental Science and Pollution Research, 2022)

Effect of pre-oxidation process on V2O5/AC catalyst for the selective catalytic reduction of NOx with NH3 - Jiahua Xie; Mengyu Li; Zihua Wu; Yiqing Zeng; Shule Zhang; Jing Liu; Qin Zhong (Environmental Science and Pollution Research, 2022)

Association Between Essential Metal Elements and the Risk of Autism in Chinese Han Population - Jiahui Ma; Jing Wu; Haibin Li; Jingyu Wang; Jisheng Han; Rong Zhang (Biological Trace Element Research, 2022)

Magma Generation of Magnetite-Rich Intermediate-Mafic Rocks and Its Mantle Processes in the Southwestern Alxa Block, NW China - Lu Tao; Hongfei Zhang; Jing Wu; Xiaochun Zhou; Liqi Zhang (Journal of Earth Science, 2022)

Infectivity and antigenicity of pseudoviruses with high-frequency mutations of SARS-CoV-2 identified in Portugal - Hai-xin Wang; Li Zhang; Zi-teng Liang; Jian-hui Nie; Jia-jing Wu; Qian-qian Li; Ru-xia Ding; Yue Zhang; Guo-qing Chen; You-chun Wang; Hui-guo Wang; Wei-jin Huang (Archives of Virology, 2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a major impact on global human health. During the spread of SARS-CoV-2, weakened host immunity and the use of vaccines with low efficacy may result in the development of more-virulent strains or strains with resistance to existing vaccines and antibodies. The prevalence of SARS-CoV-2 mutant strains differs between regions, and this variation may have an impact on the effectiveness of vaccines. In this study, an epidemiological investigation of SARS-CoV-2 in Portugal was performed, and the VSV-ΔG-G* pseudovirus system was used to construct 12 spike protein epidemic mutants, D614G, A222V+D614G, B.1.1.7, S477N+D614G, P1162R+D614G+A222V, D839Y+D614G, L176F+D614G, B.1.1.7+L216F, B.1.1.7+M740V, B.1.258, B.1.258+L1063F, and B.1.258+N751Y. The mutant pseudoviruses were used to infect four susceptible cell lines (Huh7, hACE2-293T-293T, Vero, and LLC-MK2) and 14 cell lines overexpressing ACE2 from different species. Mutant strains did not show increased infectivity or cross-species transmission. Neutralization activity against these pseudoviruses was evaluated using mouse serum and 11 monoclonal antibodies. The neutralizing activity of immunized mouse serum was not significantly reduced with the mutant strains, but the mutant strains from Portugal could evade nine of the 11 monoclonal antibodies tested. Neutralization resistance was mainly caused by the mutations S477N, N439K, and N501Y in the spike-receptor binding domain. These findings emphasize the importance of SARS-CoV-2 mutation tracking in different regions for epidemic prevention and control.

Molecular characterization of a novel fusagravirus in the phytopathogenic fungus Streptobotrys caulophylli - Siryuyumunsi Daniel; Assane Hamidou Abdoulaye; Yue Deng; Mingde Wu; Jing Zhang; Guoqing Li (Archives of Virology, 2022)

Comparative phylogeography of Acanthocalyx (Caprifoliaceae) reveals distinct genetic structures in the Himalaya–Hengduan Mountains - Qi-Yong Mu; Chih-Chieh Yu; Yan Wang; Ting-Shen Han; Hui Wang; Wen-Na Ding; Qiu-Yue Zhang; Shook Ling Low; Quan-Jing Zheng; Chuan Peng; Zheng-Yan Hu; Yao-Wu Xing (Alpine Botany, 2022)

Evolution of future precipitation extremes: Viewpoint of climate change classification - Shao Sun; Peijun Shi; Qiang Zhang; Jing'ai Wang; Jianguo Wu; Deliang Chen (International Journal of Climatology, 2022)
Climate change is often described as the average changes in temperature and precipitation; however, it is the change in climate extremes determines the levels of socioeconomic impacts related to climate change. It is generally believed that global warming drives increase in frequency, intensity and duration of precipitation extremes, but these changes vary regionally. Focusing on the relationships between evolution of extreme events and long‐term climate change, here we propose a novel classification scheme based on Kӧppen's system and changes in mean and variability of precipitation, divide the global climate into 20 different changing types and reveal the regional evolution of precipitation extremes. We find that precipitation extremes ascend significantly in wetting regions, especially in tropical and temperate zones, independent with changed variability. As for drying regions, the evolution of extremes is related to precipitation variability. An increase of extremes can still be detected in fluctuant‐drying areas, while a slight decrease can be seen in stabilized‐drying areas. It is surprising to find increase in both wetness and dryness extremes which implies higher intensity of meteorological hazards in densely populated areas. Based on the current and projected growth of population exposure to precipitation extremes, we identify some hotspots with high potential risk in the future.

Seismic capacity evaluation of a sliding isolation concrete rectangular liquid-storage structure - Xuansheng Cheng; Wei Jing; Zhongtie Wu (European Journal of Environmental and Civil Engineering, 2022)

Licochalcone L, an undescribed retrochalcone from Glycyrrhiza inflata roots - Zulfiqar Ali; Mohammed Hawwal; Mohammed M. A. Ahmed; Bharathi Avula; Amar G. Chittiboyina; Jing Li; Charles Wu; Cassandra Taylor; Yen-Ming Chan; Ikhlas A. Khan (Natural Product Research, 2022)

PCSK9 mediates dyslipidemia induced by olanzapine treatment in schizophrenia patients - Jing Huang; Jingmei Xiao; Zhuang Peng; Ping Shao; Mengxi Sun; Yujun Long; Xiaoyi Wang; Manjun Shen; Dongyu Kang; Ye Yang; Xingjie Peng; Weiyan Wang; et al. (Psychopharmacology, 2022)

Comprehensive analysis of chloroplast genome of Albizia julibrissin Durazz. (Leguminosae sp.) - Jing Zhang; Huizhen Huang; Changqing Qu; Xiaoxi Meng; Fei Meng; Xiaoyan Yao; Jing Wu; Xiaohu Guo; Bangxing Han; Shihai Xing (Planta, 2022)

Molecular cloning and functional characterization of two squalene synthase genes in Atractylodes lancea - Junxian Wu; Rui Xu; Jimei Lu; Weiwei Liu; Hanwen Yu; Mengli Liu; Jing Li; Minzhen Yin; Huasheng Peng; Liangping Zha (Planta, 2022)

Association of CDH11 with Autism Spectrum Disorder Revealed by Matched-gene Co-expression Analysis and Mouse Behavioral Studies - Nan Wu; Yue Wang; Jing-Yan Jia; Yi-Hsuan Pan; Xiao-Bing Yuan (Neuroscience Bulletin, 2022)
A large number of putative risk genes for autism spectrum disorder (ASD) have been reported. The functions of most of these susceptibility genes in developing brains remain unknown, and causal relationships between their variation and autism traits have not been established. The aim of this study was to predict putative risk genes at the whole-genome level based on the analysis of gene co-expression with a group of high-confidence ASD risk genes (hcASDs). The results showed that three gene features – gene size, mRNA abundance, and guanine-cytosine content – affect the genome-wide co-expression profiles of hcASDs. To circumvent the interference of these features in gene co-expression analysis, we developed a method to determine whether a gene is significantly co-expressed with hcASDs by statistically comparing the co-expression profile of this gene with hcASDs to that of this gene with permuted gene sets of feature-matched genes. This method is referred to as "matched-gene co-expression analysis" (MGCA). With MGCA, we demonstrated the convergence in developmental expression profiles of hcASDs and improved the efficacy of risk gene prediction. The results of analysis of two recently-reported ASD candidate genes, CDH11 and CDH9, suggested the involvement of CDH11 , but not CDH9 , in ASD. Consistent with this prediction, behavioral studies showed that Cdh11 -null mice, but not Cdh9 -null mice, have multiple autism-like behavioral alterations. This study highlights the power of MGCA in revealing ASD-associated genes and the potential role of CDH11 in ASD.

Near-epicenter weather conditions several hours before strong earthquakes (Ms ≥ 6) - Tao Chen; Lei Li; Xiao-Xin Zhang; Qi-Ming Ma; Wen Li; Shuo Ti; Han Wu; Ren-Kang Li; Jing Luo; Jian-Feng Su (Natural Hazards, 2022)

The expression and interaction proteins analysis of BjuFKF1/LKP2 in B. juncea - Jing Zeng; Anran Wu; Yuemin Yang; Liang Zhao; Li Chen; Chuanqi Wang; Xin Yang; Yanping Chen; Shiyan Liu; Pei Luo; Junli Wang (Molecular Genetics and Genomics, 2022)

Adaptations of Plutella xylostella adult females and larvae to waxy host plants - Jing-Yun Zhu; Zhong-Wen Xiang; Shi-Ze Zhang; Lin-Nan Wu; Tong-Xian Liu (Journal of Pest Science, 2022)

Characterization, functional properties, and antioxidant activities of macromolecular extracts isolated from Pyropia yezoensis - Xiaoqing Wang; Lihua Geng; Yang Yue; Ning Wu; Quanbin Zhang; Yongdong Zhou; Jing Wang (Journal of Oceanology and Limnology, 2022)

A Facile Probe for Fluorescence Turn-on and Simultaneous Naked-Eyes Discrimination of H2S and biothiols (Cys and GSH) and Its Application - Ting-Ting Liu; Shi-Jie Li; Xiao-Song Zhang; Jing Wang; Yun-Xiu Deng; Xue-Jiao Sun; Zhi-Yong Xing; Ruo-Fei Wu (Journal of Fluorescence, 2022)

Impact of environmental investment and resource endowment on regional energy efficiency: evidence from the Yangtze River Economic Belt, China - Pucha Wang; Jing Wu (Environmental Science and Pollution Research, 2022)

A novel transformation pathway of p-arsanilic acid in water by colloid ferric hydroxide under UVA light - Jing Xu; Yi Wu; Mengling Ma; Tao Luo; Jun Xia; Xiang Zhang (Environmental Science and Pollution Research, 2022)

Mutual impacts and interactions of antibiotic resistance genes, microcystin synthetase genes, graphene oxide, and Microcystis aeruginosa in synthetic wastewater - Shichao Wu; Xiyan Ji; Xin Li; Jing Ye; Wenwu Xu; Rui Wang; Meifang Hou (Environmental Science and Pollution Research, 2022)

Enhancing denitrification in constructed wetland with algae addition - Shuiping Cheng; Jing Huai; Fei Zhong; Juan Wu; Shaole Yu (Environmental Science and Pollution Research, 2022)

Environmental exposure and clinical correlates of hepatocellular carcinoma in New York City: a case only study - Hui-Chen Wu; Jing Shen; Abby Siegel; Regina M. Santella (Cancer Causes & Control, 2022)

Physiological characteristics and miRNA sequencing of two root zones with contrasting ammonium assimilation patterns in Populus - Jing Zhou; Jiang ting Wu (Genes & Genomics, 2022)

Inducible knockdown of Mycobacterium smegmatis MSMEG_2975 (glyoxalase II) affected bacterial growth, antibiotic susceptibility, biofilm, and transcriptome - Muhammad Haris; Changming Chen; Jing Wu; Muhammad Noman Ramzan; Ayaz Taj; Shanshan Sha; Hayan Ullah; Yufang Ma (Archives of Microbiology, 2022)

Potential Effect of the Intrusion of the Kuroshio Current into the South China Sea on Catches of Japanese Eel (Anguilla Japonica) in the South China Sea and Taiwan Strait - Ching-Hsien Ho; Long-Jing Wu; Zhen Lu; Bo-Yi Lu; Yang-Chi Lan (Journal of Marine Science and Engineering, 2021)
This study examined the effect of the intrusion of the Kuroshio Current (KC) into the South China Sea (SCS) and the Taiwan Strait (TS) (SCS–TS region) on changes in catches of larval A. japonica in the traditional fishing ground waters of Gaoping near southwestern Taiwan in the SCS–TS region. First, the oceanic environment and recruitment trends from 1967 to 2019 were investigated based on secondary data. Then, field surveys were conducted to obtain primary data regarding the intrusion of the KC into the SCS, as well as the changes in the fishing sites and catches of A. japonica in the fall and winter of 2014–2015. Hence, the association between oceanic conditions and the number of A. japonica migrating into the SCS–TS region was explored. From 1967 to 2019, the recruitment proportion in the fishing grounds that formed due to the Kuroshio Branch Current (PKSBC) fluctuated significantly. Overall, positive values were observed for the Oceanic Niño Index for each year with a PKSBC > 50%, corresponding to El Niño conditions. In each year with a PKSBC > 70%, a looping path and a warm–core eddy appeared.

Immunomodulatory effect of polysaccharides from the extraction of Codonopsis javanica (Blume) Hook. f. et Thomson (Campanulaceae) roots in female rats - Lanfang Wu; Mei Peng; Yongshuai Jing; Xiaosheng Yang; Juan Yang (Natural Product Research, 2021)

Genomic Analysis of the Principal Members of Antioxidant Enzymes in Simulated Stresses Response and Postharvest Physiological Deterioration in Cassava - Sang Shang; Yuqi Tang; Jing Dai; Chunlai Wu; Yan Yan; Weiwei Tie; Meiying Li; Jinghao Yang; Jian Zeng; Mingjie Chen; Wei Hu (Tropical Plant Biology, 2021)

Fiber-optic wireless sensor network using ultra-weak fiber Bragg gratings for vertical subsurface deformation monitoring - Su-Ping Liu; Bin Shi; Kai Gu; Cheng-Cheng Zhang; Jian-Hui He; Jing-Hong Wu; Guang-Qing Wei (Natural Hazards, 2021)

The Role of HMGB1 in Invasive Candida albicans Infection - JiaoJiao Wang; ChuanXin Wu; YunYing Wang; ChongXiang Chen; Jing Cheng; XiaoLong Rao; Hang Sun (Mycopathologia, 2021)

Conventional and Unconventional Hydrocarbon Resource Potential Evaluation of Source Rocks and Reservoirs: A Case Study of the Upper Xiaganchaigou Formation, Western Qaidam Basin, Northwest China - Yanchen Song; Enze Wang; Yuting Peng; Haoting Xing; Kunyu Wu; Yongxian Zheng; Jing Zhang; Na Zhang (Natural Resources Research, 2021)

LncRNA XIST knockdown alleviates LPS-induced acute lung injury by inactivation of XIST/miR-132-3p/MAPK14 pathway - Chen Li; Jian-Hua Liu; Jing Su; Wei-Jia Lin; Jian-Qing Zhao; Zhi-Hua Zhang; Qi Wu (Molecular and Cellular Biochemistry, 2021)

The role of carbonic anhydrase III and autophagy in type 2 diabetes with cardio-cerebrovascular disease - Xiao-Ming Zhang; Ying-Hong Tao; Xiu-Ling Zhou; Xi-Liang Shang; Xiao-Bo Gong; Ying-Chao Liu; Yan-Yan Huang; Gang Chen; Zhong-Yu Yu; Jian-Tao Wang; Zun-Guo Du; Guo-Feng Wu; et al. (Metabolic Brain Disease, 2021)
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases among the elderly people. The T2DM increases the risk of cardio-cerebrovascular disease (CCD), and the main pathological change of the CCD is atherosclerosis (AS). Meanwhile, the carbonic anhydrases (CAs) are involved in the formation and progression of plaques in AS. However, the exact physiological mechanism of carbonic anhydrase III (CAIII) has not been clear yet, and there are also no correlation study between CAIII protein and T2DM with CCD. The 8-week old diabetic mice (db/db −/− mice) and wild-type mice (wt mice) were feed by a normal diet till 32 weeks, and detected the carotid artery vascular opening angle using the method of biomechanics; The changes of cerebral cortex and myocardium were watched by the ultrastructure, and the autophagy were observed by electron microscope; The tissue structure, inflammation and cell injury were observed by Hematoxylin and eosin (HE) staining; The apoptosis of cells were observed by TUNEL staining; The protein levels of CAIII, IL-17, p53 were detected by immunohistochemical and Western Blot, and the Beclin-1, LC3, NF-κB were detected by Western Blot. All statistical analysis is performed using PRISM software. Compared with wt mice, db/db −/− mice’ carotid artery open angle increased significantly. Electron microscope results indicated that autophagy in db/db −/− mice cerebral cortex and heart tissue decreased and intracellular organelle ultrastructure were damaged. HE staining indicated that, db/db −/− mice’ cerebral cortex and heart tissue stained lighter, inflammatory cells infiltration, cell edema were obvious, myocardial fibers were disorder, and myocardial cells showed different degrees of degeneration. Compared with wt mice, TUNEL staining showed that there was obviously increase in db/db −/− mice cortex and heart tissue cell apoptosis. The results of immunohistochemistry and Western Blot indicated that CAIII, Beclin-1 and LC3II/I expression levels conspicuously decreased in cortex and heart tissue of db/db −/− mice, and the expression level of IL-17, NF-κB and p53 obviously increased. The carotid artery’ vascular stiffness was increased and which was probably related with formation of AS in diabetic mice. And the autophagy participated in the occurrence and development of diabetic CCD. CAIII protein might somehow be involved in the regulation of autophagy probably through affecting cell apoptosis and inflammation, but the underlying mechanism remains to be further studied.

Genetic diversity of eleven Moringa oleifera Lam. germplasm introduced to Yunnan, southwest China and their backgrounds during worldwide cultivation - Si-Teng He; Jing Yang; Jing Wei; Jiang-Chong Wu; Yi-Xing Zheng; Yan-Ping Zhang; Xing-Min Peng (Genetic Resources and Crop Evolution, 2021)

External evaluation of published population pharmacokinetic models of polymyxin B - Ya-qian Li; Kai-feng Chen; Jun-jie Ding; Hong-yi Tan; Nan Yang; Ya-qi Lin; Cui-fang Wu; Yue-liang Xie; Guo-ping Yang; Jing-Jing Liu; Qi Pei (European Journal of Clinical Pharmacology, 2021)

Iron (III) hydroxocomplex-methyl viologen dication system as a prospective tool for determination of hydroxyl radical reaction rate constants with environmental pollutants - Yuliya E. Tyutereva; Vyacheslav P. Grivin; Jing Xu; Feng Wu; Victor F. Plyusnin; Ivan P. Pozdnyakov (Environmental Science and Pollution Research, 2021)

Bibliometric analysis of phosphogypsum research from 1990 to 2020 based on literatures and patents - Yunmeng Cao; Yue Cui; Xiaokun Yu; Tong Li; I-Shin Chang; Jing Wu (Environmental Science and Pollution Research, 2021)

Heavy Metals Present in the Soils from Extremely Large Opencast Iron Mine Pit - Siping Niu; Qin Fang; Jianghua Yu; Jing Wu (Bulletin of Environmental Contamination and Toxicology, 2021)

Long-Term Consistent Recalibration of VIRR Solar Reflectance Data Record for Fengyun Polar-Orbiting Satellites - Ling Sun; Hong Qiu; Ronghua Wu; Jing Wang; Liyang Zhang; Peng Zhang (Journal of Meteorological Research, 2021)

Keratin 1 maintains the intestinal barrier in ulcerative colitis - Jing Wu; Junkun Niu; Maojuan Li; Yinglei Miao (Genes & Genomics, 2021)

Toward Understanding the Extreme Floods over Yangtze River Valley in June–July 2020: Role of Tropical Oceans - Shaolei Tang; Jing-Jia Luo; Jiaying He; Jiye Wu; Yu Zhou; Wushan Ying (Advances in Atmospheric Sciences, 2021)

Atmospheric brightening counteracts warming‐induced delays in autumn phenology of temperate trees in Europe - Zhaofei Wu; Shouzhi Chen; Hans J. De Boeck; Nils Christian Stenseth; Jing Tang; Yann Vitasse; Shuxin Wang; Constantin Zohner; Yongshuo H. Fu (Global Ecology and Biogeography, 2021)
Aim Ongoing climate warming has been widely reported to delay autumn phenology, which in turn impacts carbon, water, energy and nutrient balances at regional and global scales. However, the underlying mechanisms of autumn phenology responses to climate change have not been fully elucidated. The aims of this study were to determine whether brightening that was defined as the increase of surface solar radiation and warming during recent decades affect autumn phenology in opposite directions and explore the underlying mechanisms. Location Central Europe. Time period 1950–2016. Major taxa studied Four dominant European tree species in central Europe: Aesculus hippocastanum , Betula pendula , Fagus sylvatica and Quercus robur . Methods We investigated the temporal trends of leaf senescence, preseason temperature and radiation by separating the period of 1950–2016 into two sub‐periods (1950–1982 and 1983–2016) and determined the relationship between temperature, radiation and leaf senescence using partial correlation analysis. Results We found a significant warming and brightening trend after the 1980s in central Europe, yet this led to only slight delays in leaf senescence that cannot be explained by the well‐known positive correlation between leaf senescence and autumn warming. Interestingly, we found opposite effects between warming (partial correlation coefficient, r = .37) and brightening ( r = −.23) on leaf senescence. In addition, the temperature sensitivity of leaf senescence decreased with increasing radiation (−5.08 days/℃/10 8 J/m 2 ). Main conclusions The results suggested that brightening accelerated the leaf senescence dates, counteracting the warming‐induced delays in leaf senescence, which may be attributed to photooxidative stress and/or sink limitation. This emphasizes the need to consider radiation to improve the performance of autumn phenology models.

Active Methanotrophs and Their Response to Temperature in Marine Environments: An Experimental Study - Jing Li; Xiaoqing Xu; Changling Liu; Nengyou Wu; Zhilei Sun; Xingliang He; Ye Chen (Journal of Marine Science and Engineering, 2021)
Aerobic methane (CH4) oxidation plays a significant role in marine CH4 consumption. Temperature changes resulting from, for example, global warming, have been suggested to be able to influence methanotrophic communities and their CH4 oxidation capacity. However, exact knowledge regarding temperature controls on marine aerobic methane oxidation is still missing. In this study, CH4 consumption and the methanotrophic community structure were investigated by incubating sediments from shallow (Bohai Bay) and deep marine environments (East China Sea) at 4, 15, and 28 °C for up to 250 days. The results show that the abundance of the methanotrophic population, dominated by the family Methylococcaceae (type I methanotrophs), was significantly elevated after all incubations and that aerobic methane oxidation for both areas had a strong temperature sensitivity. A positive correlation between the CH4 oxidation rate and temperature was witnessed in the Bohai Bay incubations, whereas for the East China Sea incubations, the optimum temperature was 15 °C. The systematic variations of pmoA OTUs between the Bohai Bay and East China Sea incubations indicated that the exact behaviors of CH4 oxidation rates with temperature are related to the different methanotrophic community structures in shallow and deep seas. These results are of great significance for quantitatively evaluating the biodegradability of CH4 in different marine environments.

Cytotoxic triterpenoid glycosides from leaves of Cyclocarya paliurus - Hui-Hui Sun; Wen-Yan Lv; Jie Tan; Yu-Cheng Tang; Hui Zhu; Jian-Bo Qu; Jing Li; Jian-Ping Wu; Xi-Wen Chang; Zhi-Chun Yang; Wen-Xuan Wang; Zu-Hui Chen; et al. (Natural Product Research, 2021)

Developments in Biological Mechanisms and Treatments for Negative Symptoms and Cognitive Dysfunction of Schizophrenia - Qiongqiong Wu; Xiaoyi Wang; Ying Wang; Yu-Jun Long; Jing-Ping Zhao; Ren-Rong Wu (Neuroscience Bulletin, 2021)
The causal mechanisms and treatment for the negative symptoms and cognitive dysfunction in schizophrenia are the main issues attracting the attention of psychiatrists over the last decade. The first part of this review summarizes the pathogenesis of schizophrenia, especially the negative symptoms and cognitive dysfunction from the perspectives of genetics and epigenetics. The second part describes the novel medications and several advanced physical therapies (e.g., transcranial magnetic stimulation and transcranial direct current stimulation) for the negative symptoms and cognitive dysfunction that will optimize the therapeutic strategy for patients with schizophrenia in future.

Evaluation of the antifungal activity of Lysurus mokusin extract against Pestalotiopsis neglecta and GC–MS analysis of the active components - Lian-Nan Lin; Jing Yang; Guo-Cai Zhang; Xiao-Bo Zhang; Ting-Yu Wang; De-Dong Wu (Journal of Plant Pathology, 2021)

Toxicity of chlortetracycline and oxytetracycline on Vallisneria natans (Lour.) Hare - Jing Li; Lu Yang; Zhonghua Wu (Environmental Science and Pollution Research, 2021)

The role of mechanical harvesting on the recession of aquatic vegetation under an extreme water level increase in a eutrophic shallow lake - Changtao Yang; Jing Nan; Jianhua Li; Yi Lin; Jie Yu; Jianbin Wu; Xiaobing Shen (Environmental Science and Pollution Research, 2021)

Growth and antioxidant response in Spirodela polyrrhiza under linear alkylbenzene sulfonate, naphthalene and their joint stress - Lulu Chai; Jing Li; Yizhe Zhang; Yilin Liu; Zhonghua Wu (Environmental Science and Pollution Research, 2021)

Effects of air pollutant emission on the prevalence of respiratory and circulatory system diseases in Linyi, China - Xin Wu; Dong Li; Meihui Feng; Houfeng Liu; Hongmei Li; Jing Yang; Pengcheng Wu; Xunjie Lei; Min Wei; Xin Bo (Environmental Geochemistry and Health, 2021)

The effect of the PARK16 rs11240572 variant on brain structure in Parkinson's disease - Lu-yan Gu; Shao-bing Dai; Cheng Zhou; Ting Gao; Jing-jing Wu; Yi Fang; Xiao-jun Guan; Tao Guo; Ran Zheng; Chongyao Jin; Xiao-jun Xu; Zhe Song; et al. (Brain Structure and Function, 2021)

Evaluation of grain size and content of nonplastic fines on undrained behavior of sandy soils - Ling-Yu Xu; Fei Cai; Jing-Zhe Zhang; Dong-Dong Pan; Qi Wu; Guo-Xing Chen (Marine Georesources & Geotechnology, 2021)

Structural and Functional Changes in the Cerebellum and Brainstem in Patients with Benign Paroxysmal Positional Vertigo - Qian Zhu; Wei Chen; Yangyang Cui; Jing Wu; Liang Shu; Xuhong Sun; Zhaoxia Qin; Wei Tang; Tingting Gao; Qian Xu; Chun-Yan Jiang; Jianren Liu; et al. (The Cerebellum, 2021)

Transcriptome sequencing reveals terpene biosynthesis pathway genes accounting for volatile terpene of tree peony - Rongchen Li; Ziyao Li; Pingsheng Leng; Zenghui Hu; Jing Wu; Dequan Dou (Planta, 2021)

Hesperetin ameliorates diabetes-associated anxiety and depression-like behaviors in rats via activating Nrf2/ARE pathway - Xia Zhu; Yu-Meng Zhang; Meng-Ya Zhang; Ya-Jing Chen; Yao-Wu Liu (Metabolic Brain Disease, 2021)

Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway - Kun Zhao; Jing Zhang; Tianhua Xu; Chuanxi Yang; Liqing Weng; Tingting Wu; Xiaoguang Wu; Jiaming Miao; Xiasheng Guo; Juan Tu; Dong Zhang; Bin Zhou; et al. (Journal of Zhejiang University-SCIENCE B, 2021)

Immunoglobulin G4-related disease: case report and literature review - Liang-Liang Dong; Irfan Sahail Sheikh; Ai-Hua Huang; Xiao-Hong Wu; En-Guo Chen; Ke-Jing Ying (Immunologic Research, 2021)

Humoral immune durability of IgG for anti-SARS-CoV-2 in the normal pregnant women in Wuhan, China - Hongwen Ma; Jing Peng; Ruobing Li; Xuan Zheng; Shiyao Wu; Heng Yin; Min Li; Liu Qin; Fei Tang; Yun Zhao (Immunologic Research, 2021)

Metatranscriptomic analysis reveals active microbes and genes responded to short-term Cr(VI) stress - Zhengsheng Yu; Yaxin Pei; Shuai Zhao; Apurva Kakade; Aman Khan; Monika Sharma; Hajira Zain; Pengya Feng; Jing Ji; Tuoyu Zhou; Haoyang Wang; Jingyuan Wu; et al. (Ecotoxicology, 2021)

Multivariate machine learning‐based language mapping in glioma patients based on lesion topography - Nan Zhang; Binke Yuan; Jing Yan; Jingliang Cheng; Junfeng Lu; Jinsong Wu (Brain Imaging and Behavior, 2021)

Exogenous Gibberellin GA3 Enhances Defense Responses in Rice to the Brown Planthopper Nilaparvata lugens (Stål) - Wanwan Wang; Nuo Jin; Xiaochang Mo; Jun Wu; Jing Lu; Yonggen Lou (Journal of Plant Biology, 2021)

Faster recovery of soil biodiversity in native species mixture than in Eucalyptus monoculture after 60 years afforestation in tropical degraded coastal terraces - Wenjia Wu; Luhui Kuang; Yue Li; Lingfeng He; Zhijian Mou; Faming Wang; Jing Zhang; Jun Wang; Zhi’an Li; Hans Lambers; Jordi Sardans; Josep Peñuelas; et al. (Global Change Biology, 2021)
Afforestation is an effective method to restore degraded land. Afforestation methods vary in their effects on ecosystem multifunctionality, but their effects on soil biodiversity have been largely overlooked. Here, we mapped the biodiversity and functioning of multiple soil organism groups resulting from diverse afforestation methods in tropical coastal terraces. Sixty years after afforestation from bare land (BL), plant species richness and the abundance of plant litter (398 ± 85 g m −2 ) and plant biomass (179 ± 3.7 t ha −1 ) in native tree species mixtures (MF) were restored to the level of native forests (NF; 287 ± 21 g m −2 and 243.0 ± 33 t ha −1 , respectively), while Eucalyptus monoculture (EP) only successfully restored the litter mass (388 ± 43 g m −2 ) to the level of NF. Soil fertility in EP and MF was increased but remained lower than in NF. For example, soil nitrogen and phosphorus concentrations in MF (1.2 ± 0.2 g kg −1 and 408 ± 49 mg kg −1 , respectively; p −1 and 523 ± 24 mg kg −1 , respectively; p

Paeonol assists fluconazole and amphotericin B to inhibit virulence factors and pathogenicity of Candida albicans - Min Pan; Qirui Wang; Ting Cheng; Daqiang Wu; Tianming Wang; Guiming Yan; Jing Shao (Biofouling, 2021)

Experimental study on integrated and autonomous conductivity-temperature-depth (CTD) sensor applied for underwater glider - Bin Lv; Hai-lin Liu; Yi-fan Hu; Cheng-xuan Wu; Jie Liu; Hai-jing He; Jie Chen; Jian Yuan; Zhao-wen Zhang; Lin Cao; Hui Li (Marine Georesources & Geotechnology, 2021)

Isopentenyl Diphosphate Isomerase (IPI) Gene Silencing Negatively Affects Patchouli Alcohol Biosynthesis in Pogostemon cablin - Wuping Yan; Yuzhang Yang; Yougen Wu; Jing Yu; Junfeng Zhang; Dongmei Yang; Zeeshan Ul Haq Muhammad (Plant Molecular Biology Reporter, 2021)

Co-editing PINK1 and DJ-1 Genes Via Adeno-Associated Virus-Delivered CRISPR/Cas9 System in Adult Monkey Brain Elicits Classical Parkinsonian Phenotype - Hao Li; Shihao Wu; Xia Ma; Xiao Li; Tianlin Cheng; Zhifang Chen; Jing Wu; Longbao Lv; Ling Li; Liqi Xu; Wenchao Wang; Yingzhou Hu; et al. (Neuroscience Bulletin, 2021)
Whether direct manipulation of Parkinson’s disease (PD) risk genes in the adult monkey brain can elicit a Parkinsonian phenotype remains an unsolved issue. Here, we used an adeno-associated virus serotype 9 (AAV9)-delivered CRISPR/Cas9 system to directly co-edit PINK1 and DJ-1 genes in the substantia nigras (SNs) of two monkey groups: an old group and a middle-aged group. After the operation, the old group exhibited all the classic PD symptoms, including bradykinesia, tremor, and postural instability, accompanied by key pathological hallmarks of PD, such as severe nigral dopaminergic neuron loss (>64%) and evident α-synuclein pathology in the gene-edited SN. In contrast, the phenotype of their middle-aged counterparts, which also showed clear PD symptoms and pathological hallmarks, were less severe. In addition to the higher final total PD scores and more severe pathological changes, the old group were also more susceptible to gene editing by showing a faster process of PD progression. These results suggested that both genetic and aging factors played important roles in the development of PD in the monkeys. Taken together, this system can effectively develop a large number of genetically-edited PD monkeys in a short time (6–10 months), and thus provides a practical transgenic monkey model for future PD studies.

Descending Modulation of Spinal Itch Transmission by Primary Somatosensory Cortex - Zi-Han Wu; Han-Yu Shao; Yuan-Yuan Fu; Xiao-Bo Wu; De-Li Cao; Sheng-Xiang Yan; Wei-Lin Sha; Yong-Jing Gao; Zhi-Jun Zhang (Neuroscience Bulletin, 2021)

Gastrodin Regulates the Notch Signaling Pathway and Sirt3 in Activated Microglia in Cerebral Hypoxic-Ischemia Neonatal Rats and in Activated BV-2 Microglia - Jing Guo; Xiao-Li-Na Zhang; Zhang-Rui Bao; Xue-Ke Yang; Ling-Shuang Li; Yu Zi; Fan Li; Chun-Yun Wu; Juan-Juan Li; Yun Yuan (NeuroMolecular Medicine, 2021)

Phelligridin D from Inonotus obliquus attenuates oxidative stress and accumulation of ECM in mesangial cells under high glucose via activating Nrf2 - Yan Li; Yang Zhou; Jing Wu; Jindong Li; Huankai Yao (Journal of Natural Medicines, 2021)