Disruption of the lung-gut-brain axis is responsible for cortex damage induced by pulmonary exposure to zinc oxide nanoparticles - Lingbing Zhang; Yandan Zhang; Xuejun Jiang; Lejiao Mao; Yinyin Xia; Yinzhen Fan; Na Li; Ziqi Jiang; Xia Qin; Yu Jiang; Gang Liu; Feng Qiu; et al. (Toxicology, 2023)

Characteristics of microbiota, core sulfate-reducing taxa and corrosion rates in production water from five petroleum reservoirs in China - Lei Zhou; Jun Wu; Jia-Heng Ji; Jie Gao; Yi-Fan Liu; Biao Wang; Shi-Zhong Yang; Ji-Dong Gu; Bo-Zhong Mu (Science of The Total Environment, 2023)

Surprising leopard restoration in fragmented ecosystems reveals connections as the secret to conservation success - Fu Yanwen; Zhao Guojing; Dai Wenqian; Wang Yue; Li Jiawei; Tan Mengyu; Li Yan; Liu Haoran; Xie Bing; Jin Xiao; Fan Enyu; Zhao Lulu; et al. (Science of The Total Environment, 2023)

Dynamic installation of offshore torpedo anchors in spatially variable clay - Jiang Tao Yi; Chao Fan Liu; Shi Jie Xu; Zhen Wang; Miao Jun Sun (Ocean Engineering, 2023)

Response of activated sludge to antibiotics stress: Neglected legacy effects - Zhong-Xing Zhang; Xiao-Yan Fan; Xing Li; Yu-Xi Gao; Jun-Ru Zhao (Journal of Water Process Engineering, 2023)

The in-situ and ex-situ adsorption of iron flocs generated by electrocoagulation: Application for nickel, fluoride and methyl orange removal - Yaqi Fan; Isaac D. Tegladza; Guangqiang Zhang; Hongliang Dai; Bing Liao; Jun Lu (Journal of Water Process Engineering, 2023)

Soil water dynamics and groundwater evolutions of check dams under natural rainfall reduction in semi-arid areas - Zhanbin Luo; Jun Fan; Ming'an Shao; Wei Hu; Qian Yang; Shougang Zhang (Journal of Hydrology, 2023)

Numerical study of the influence of loading rate on fracture mechanism in elastoplastic rock-like materials with a modified phase-field model - Shi-Fan Liu; Wei Wang; Ya-Jun Cao; Hai-Feng Li; Jian-Fu Shao (International Journal of Rock Mechanics and Mining Sciences, 2023)

Improving the xanthine oxidase and adenosine deaminase inhibitory activities of Flos Sophorae Immaturus by ultrasound-assisted heating treatments - Jun Li; Yuhong Gong; Jinwei Li; Liuping Fan (Food Bioscience, 2023)

Hydrothermal synthesis of sewage sludge biochar for activation of persulfate for antibiotic removal: Efficiency, stability and mechanism - Xiulei Fan; Weiliang Zhang; Yiming Liu; Shang Shi; Yue Cui; Ziyu Zhao; Jun Hou (Environmental Research, 2023)

IFI44L as a novel epigenetic silencing tumor suppressor promotes apoptosis through JAK/STAT1 pathway during lung carcinogenesis - Yong Zeng; Hong-qiang Chen; Zhe Zhang; Jun Fan; Jing-zhi Li; Shi-meng Zhou; Na Wang; Su-peng Yan; Jia Cao; Jin-yi Liu; Zi-yuan Zhou; Wen-bin Liu (Environmental Pollution, 2023)

Soil ammonium (NH4+) toxicity thresholds for restoration grass species - Huixian Yang; Jun Zhou; Jiasai Fei; Kaidong Ci; Demin Li; Jianbo Fan; Chaoyang Wei; Jiani Liang; Ruizhi Xia; Jing Zhou (Environmental Pollution, 2023)

Structural dynamic response reconstruction using self-attention enhanced generative adversarial networks - Gao Fan; Zhengyan He; Jun Li (Engineering Structures, 2023)

Repaired surface structural imperfection of tin Wide-Bandgap perovskite films for photovoltaic application - Tian-Yu Teng; Fan Hu; Yan-Hui Lou; Jun-Jie Cao; Chun-Hao Chen; Yi-Ran Shi; Kai-Li Wang; Jing Chen; Zhao-Kui Wang; Liang-Sheng Liao (Chemical Engineering Journal, 2023)

Efficient photocatalytic H2 generation over In2.77S4/NiS2/g-C3N4 S-scheme heterojunction using NiS2 as electron-bridge - Zhuonan Lei; Xiaofei Cao; Jun Fan; Xiaoyun Hu; Jun Hu; Neng Li; Tao Sun; Enzhou Liu (Chemical Engineering Journal, 2023)

Thermally insulating composite aerogel with both active absorption and passive insulation functions based on azobenzene-modified chitosan/oligomeric β-cyclodextrin - Chuan-Yan Huang; Jun-Feng Feng; Guo-Chen Li; Li-Guo Liao; Shu-Ting Fan; Jia-Xin Wang; Sheng Zhang; Bang-Jing Li (Chemical Engineering Journal, 2023)

Strategic approach for achieving high indoor efficiency of perovskite solar Cells: Frustration of charge recombination by dipole induced homogeneous charge distribution - Min Jun Choi; Seok Woo Lee; Minwoo Lee; So Jeong Shin; Moonyong Kim; Gyeong G. Jeon; Sang Eun Yoon; Fan Xiangyang; Bo Ram Lee; Jan Seidel; Jae Sung Yun; Dong Wook Chang; et al. (Chemical Engineering Journal, 2023)

Tumor microenvironment activated nanoreactors for chemiluminescence imaging-guided simultaneous elimination of breast tumors and tumor-resident intracellular pathogens - Xinxin Li; Ting Wu; Zefan Zhang; Sha Liu; Hongmei Cui; Zhongxiong Fan; Baodui Wang; Jun Hai (Chemical Engineering Journal, 2023)

Elevated Levels of Naturally-Occurring Autoantibodies Against the Extracellular Domain of p75NTR Aggravate the Pathology of Alzheimer’s Disease - Chen-Yang He; Ding-Yuan Tian; Si-Han Chen; Wang-Sheng Jin; Yuan Cheng; Jia-Yan Xin; Wei-Wei Li; Gui-Hua Zeng; Cheng-Rong Tan; Jie-Ming Jian; Dong-Yu Fan; Jun-Rong Ren; et al. (Neuroscience Bulletin, 2023)

Rock characteristics and dynamic fragmentation process of the 2018 Daanshan rockslide in Beijing, China - Tian-zhen Fan; Hui-cong An; Chao-jun Ouyang; Dong-po Wang (Journal of Mountain Science, 2023)

Occurrence and exposure risk assessment of pesticide residues in green tea samples cultivated in Hangzhou area, China - Ji-cai Fan; Jun An; Ren Ren; Shao-ying Liu; Hua-li He; Gang Zhao (Food Additives & Contaminants Part B-Surveillance, 2023)

TET1 involved in bisphenol A induced TM3 Leydig cell toxicity by regulating Cav3.3 hydroxymethylation - Shi-meng Zhou; Wen-bo Yuan; Jing-zhi Li; Hong-qiang Chen; Yong Zeng; Na Wang; Jun Fan; Zhe Zhang; Yuanyuan Xu; Jia Cao; Wen-bin Liu (Chemosphere, 2023)

Advancing charge carriers separation and transformation by nitrogen self-doped hollow nanotubes g-C3N4 for enhancing photocatalytic degradation of organic pollutants - Xinlan Zhen; Changzheng Fan; Lin Tang; Jun Luo; Linrui Zhong; Yuying Gao; Mingjuan Zhang; Jangfu Zheng (Chemosphere, 2023)

Residue depletion of danofloxacin in Yellow River carp (Cyprinus carpio haematopterus) following multiple oral administration - Zhe-Wen Song; Fang Yang; Yue Liu; Hao-Tian Shao; Mei Zhang; Jun-Cheng Chen; Kai-Li Ma; Fan Yang (Aquaculture, 2023)

Hypoxia alters glucose and lipid metabolisms in golden pompano (Trachinotus blochii) - Tian Jiang; Jun Long Sun; Yue Gu; Fu Cheng Yao; Ye Song Liang; Yi Fan Liu; Kai Xi Zhang; Fei Biao Song; Li Zhou; Zhong Wei Wang; Jian Fang Gui; Jian Luo (Aquaculture, 2023)

Collaborative optimization of electric bus line scheduling with multiple charging modes - Dong-Fan Xie; Ya-Peng Yu; Guang-Jing Zhou; Xiao-Mei Zhao; Yong-Jun Chen (Transportation Research Part D: Transport and Environment, 2023)

Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles - Ziqi Jiang; Yu Jiang; Jingchuan Fan; Jun Zhang; Ge Xu; Yinzhen Fan; Liyu Zhang; Xia Qin; Xuejun Jiang; Lejiao Mao; Gang Liu; Chengzhi Chen; et al. (Toxicology Letters, 2023)

Simultaneous nitrification, denitrification and phosphorus removal: What have we done so far and how do we need to do in the future? - Tong Wu; Shan-Shan Yang; Le Zhong; Ji-Wei Pang; Luyan Zhang; Xue-Fen Xia; Fan Yang; Guo-Jun Xie; Bing-Feng Liu; Nan-Qi Ren; Jie Ding (Science of The Total Environment, 2023)

Unprecedented acid-tolerant ultrathin membranes with finely tuned sub-nanopores for energetic-efficient molecular sieving - Fan Yang; Yanqiu Zhang; Junhui Huang; Gang Gao; Jiaqi Zhu; Jun Ma; Lu Shao (Science Bulletin, 2023)

Real-world characterization of carbonaceous substances from industrial stationary and process source emissions - Min Cui; Yuanyuan Xu; Fan Zhang; Caiqing Yan; Jun Li; Mei Zheng; Yingjun Chen (Science of The Total Environment, 2023)

Numerical investigation on nonlinear evolution behavior and water particle velocity of wave crests for narrow-band wave field with Gaussian spectrum - Jun Fan; Aifeng Tao; Shuya Xie; Di Wu; Gang Wang (Ocean Engineering, 2023)

Genetic pattern of the Albian volcanic rocks in the Ziruco area, Northern Tibet: Implications for A-type granites - Bo-Chuan Zhang; Jian-Jun Fan; An-Bo Luo (Lithos, 2023)

Rare disperse elements in epithermal deposit: Insights from LA–ICP–MS study of sphalerite at Dalingkou, South China - Ming-Sen Fan; Pei Ni; Jun-Yi Pan; Guo-Guang Wang; Jun-Ying Ding; Shu-Wu Chu; Wen-Sheng Li; Wen-Qing Huang; Ren-Zhi Zhu; Zhe Chi (Journal of Geochemical Exploration, 2023)

Sustainable lanthanum-attapulgite/alginate hydrogels with enhanced mechanical strength for selective phosphate scavenging - Shuai Liu; Fuqiang Fan; Zhaokui Ni; Jun Liu; Shengrui Wang (Journal of Cleaner Production, 2023)

Terrestrial rather than volcanic mercury inputs to the Yangtze Platform (South China) during the Ordovician-Silurian transition - Yu Liu; Yuanchun Li; Mingcai Hou; Jun Shen; Thomas J. Algeo; Junxuan Fan; Xiaolin Zhou; Qing Chen; Zongyuan Sun; Chao Li (Global and Planetary Change, 2023)

Experimental study on effects of air-staged strategy and NH3 co-firing ratios on NO formation characteristics in ammonia/coal co-firing process - Xin Wang; Weidong Fan; Jun Chen; Guanyu Feng; Xiang Zhang (Fuel, 2023)

Simple and high-precision DFT-QSPR prediction of enthalpy of combustion for sesquiterpenoid high-energy–density fuels - Hang Yang; Zhi-Jiang Yang; Qi-Fan Yang; Xin-Miao Wei; Yu-Quan Yuan; Liang-Liang Wang; Yan-Fei Hu; Jun-Jie Ding (Fuel, 2023)

Effect of solvent swelling with different enhancement methods on the microstructure and pyrolysis performance of Hefeng subbituminous coal - Hui Kan; Yue Wang; Wen-Long Mo; Xian-Yong Wei; Hong-Yu Mi; Kong-Jun Ma; Mei-Xia Zhu; Wen-Cang Guo; Jia Guo; Jun-Min Niu; Xing Fan (Fuel, 2023)

Effect of sequential thermal dissolution on the structure and pyrolysis characteristics of Naomaohu lignite - Xiao-Bo Hu; Hao Xu; Wen-Long Mo; Xing Fan; Wen-Cang Guo; Jia Guo; Jun-Min Niu; Hong-Yu Mi; Ya-Ya Ma; Xian-Yong Wei (Fuel, 2023)

Associations between greenspace surrounding schools and lipid levels in Chinese children and teenagers - Li-Xin Hu; Shujun Fan; Yinghua Ma; Xiao-Xuan Liu; Wen-Wen Bao; Yuming Guo; Li-Wen Hu; Gongbo Chen; Xiao-Wen Zeng; Zhiyong Zou; Bo-Yi Yang; Jun Ma; et al. (Environmental Pollution, 2023)

The association of air pollutants with hospital outpatient visits for child and adolescence psychiatry in Shenzhen, China - Dong Fang; Wang Bing; Han Yao-hui; Jing Chun-xia; Zhang Ying; Liu Xing-li; Tian Hua-wei; Xiang Ying-jun; Liao Wan-wei; Li Xiu-juan; Fan Dong-yong; Yang Wei-ting; et al. (Environmental Research, 2023)

East Asian lake hydrology modulated by global sea-level variations in the Eocene warmhouse - Yiquan Ma; Majie Fan; Mingsong Li; James G. Ogg; Chen Zhang; Jun Feng; Chunhua Zhou; Xiaofeng Liu; Yongchao Lu; Huimin Liu; James S. Eldrett; Chao Ma (Earth and Planetary Science Letters, 2023)

Cation-doped V2O5 microsphere as a bidirectional catalyst to activate sulfur redox reactions for lithium-sulfur batteries - Fan-Jun Liu; Wen-Lin Luo; Ze Zhang; Ji Yu; Jian-Xin Cai; Zhen-Yu Yang (Chemical Engineering Journal, 2023)

Microwave discharge for rapid introduction of bimetallic-synergistic configuration to conductive catecholate toward long-term supercapacitor - Huiyu Jiang; Jinglin Xian; Rong Hu; Shiyun Mi; Liyun Wei; Guangyu Fang; Zhiao Wu; Siqi Xu; Mingzhao Fan; Kaisi Liu; Huimin Yu; Weilin Xu; et al. (Chemical Engineering Journal, 2023)

Enhancing hydrodeoxygenation-isomerization of FAME over M-SAPO-11 in one-step process: Effect of in-situ isomorphic substitution of transition metals and synergy of PtxSny alloy - Xingyong Li; Qiyuan Fan; Yankun Wu; Xin Lin; Sihan Ma; Shuirong Li; Yueyuan Ye; Dechao Wang; Jun Cheng; Zhifeng Zheng; Jianchun Jiang (Chemical Engineering Journal, 2023)

Iron-induced electron modulation of nickel hydroxide/carbon nanotubes composite to effectively boost the oxygen evolution activity - Yi Wang; Yantao Zheng; Jinhao Xie; Minchang Lv; Jun Luo; Fan Yang; Yanxia Yu; Xihong Lu (Chemical Engineering Journal, 2023)

Cationic molecular probes based on aggregation-induced emission for fluorescent sensing and super-resolution imaging of insulin fibrosis - Li-Jun Mei; Cheng Fan; Chu-Ran Xu; Qi Yu; Chong Li; Ya-Long Wang; Ming-Qiang Zhu (Chemical Engineering Journal, 2023)

Engineering ZnSn(OH)6 with ternary active sites-directed hydroxyl vacancies for robust deep C6H6 photo-oxidation: Experiment and DFT calculations - Yuhan Li; Bangfu Chen; Ping Ouyang; Youyu Duan; Wee-Jun Ong; Fan Dong (Chemical Engineering Journal, 2023)

Polyamide microplastics act as carriers for cephalexin in the anammox process - Ye Wang; Dong-Qi Huang; Jun-Hui Yang; Gui-Feng Li; Ye-Xing Zhou; Jia-Yi Zhang; Ya Lu; Nian-Si Fan; Ren-Cun Jin (Chemical Engineering Journal, 2023)

Sulfur cycle contributes to stable autotrophic denitrification and lower N2O accumulation in electrochemically integrated constructed wetlands: Electron transfers patterns and metagenome insights - Yingmu Wang; Shikang Xie; Jian Zhou; Gongduan Fan; Lei He; Xing Fan; Shi Chen; Jun Yang; Junge Xu; Qiang He (Chemical Engineering Journal, 2023)

Chitosan based photothermal scaffold fighting against bone tumor-related complications: Recurrence, infection, and defects - Yao Zhao; Xu Peng; Xiaoyang Xu; Mingzhen Wu; Fan Sun; Qiangwei Xin; Hongbo Zhang; Liangrui Zuo; Yilin Cao; Yuhang Xia; Jun Luo; Chunmei Ding; et al. (Carbohydrate Polymers, 2023)

Polar Co9S8 anchored on Pyrrole-Modified graphene with in situ growth of CNTs as multifunctional Self-Supporting medium for efficient Lithium-Sulfur batteries - Lin Sun; Yanxiu Liu; Jie Xie; Lele Fan; Jun Wu; Ruiyu Jiang; Zhong Jin (Chemical Engineering Journal, 2023)

A mathematical model of critical releasable charge for R290 indoor leakage of split-type household air conditioners - Qian Ning; Guogeng He; Jun Xiong; Mingjing Fan; Xiao Li (Building and Environment, 2023)

Role of quorum sensing-based regulation in development of anaerobic ammonium oxidation process - Jun-Hui Yang; Dong-Qi Huang; Yin-Ce Geng; Yi-Rong Ling; Nian-Si Fan; Ren-Cun Jin (Bioresource Technology, 2023)

Source apportionment of VOCs based on photochemical loss in summer at a suburban site in Beijing - Yajun Wu; Xiaolong Fan; Yan Liu; Jingqiao Zhang; Han Wang; Luna Sun; Tiange Fang; Hongjun Mao; Jun Hu; Lin Wu; Jianfei Peng; Shulan Wang (Atmospheric Environment, 2023)

Impact of environmental factors on the diversity of nitrogen-removal bacteria in wetlands in the Sanmenxia Reservoir of the Yellow River - Tao Li; Yiqiao Zhou; Fan Yang; Qingsong Guan; Qingbin Li; Hongyan Liang; Jun Zhao (Journal of Soils and Sediments, 2023)

Long-Term Phosphorus Addition Strongly Weakens the Carbon Sink Function of a Temperate Peatland - Fan Lu; Jianghua Wu; Boli Yi; Zhiwei Xu; Meng Wang; Sebastian Sundberg; Zhao-Jun Bu (Ecosystems, 2023)

A viable synthesis route of Ag Cu bimetallic nanoclusters on halloysite nanotubes and the study of the antibacterial properties - Yi Jin; Fengzhen Zhang; Jingyuan Fan; Hua-Jun S. Fan (Applied Clay Science, 2023)

miR-27a-3p targets NR5A2 to regulate CYP19A1 expression and 17-β estradiol synthesis in ovine granulosa cells - Hongbing Gui; Fan Li; Cheng Chen; Qiuyi Zhu; Chenjian Zhang; Jun Zhang; Chunhua Meng; Yong Qian; Shaoxian Cao; Yinxia Li (Animal Reproduction Science, 2023)

Physiological and transcriptome analysis of Mytilus coruscus in response to Prorocentrum lima and microplastics - Xiao-wen Tang; Rong Yu; Mei-hua Fan; Zhi Yang; Zhi Liao; Zong-xin Yang; Chen-ying Xie; Yu-kun Xuan; Jian-xin Wang; Xiao-lin Zhang; Xiao-jun Yan (Frontiers in Marine Science, 2022)
Nowadays, diarrheic shellfish toxicity (DSP) toxin and microplastics (MPs) are commonly found in coastal waters worldwide. Due to their widespread use, their persistence and toxicity, they may induce adverse effects on Mytilus coruscus . However, the underlying toxic mechanisms of DSP and MPs on M. coruscus remain unclear. This study explored the physiological index and transcriptome change of the digestive gland of adult M. coruscus exposed for 3 days to polystyrene (PS) MPs (0.2 mg/L, 90-100 μm) and Prorocentrum lima alone or in combination. The results showed that the CAT activity and MDA content significantly increased, respiration rate and feeding rate significantly decreased. The combination of MPs and P. lima caused more structural damage to the rough surface endoplasmic reticulum and mitochondria in the digestive glands of M. coruscus . The transcriptome analysis showed that 485 and 220 genes were up- and down-regulated, respectively, after exposure to P. lima ; 1,989 up-regulated DEGs and 1,098 down-regulated DEGs were identified after exposure to MP treatment, and 1,004 up-regulated DEGs and 664 down-regulated DEGs were identified after exposure to the combination of P. lima and MPs. The DEGs were mainly enriched in the lysosome, mRNA surveillance pathway, carbon metabolism, the mTOR signaling pathway, the complement and coagulation cascades, and the TNF signaling pathway. The MP, P. lima exposure mainly induced the expression of RNA-binding protein musashi, serine/arginine repetitive matrix protein 1, low affinity immunoglobulin epsilon Fc receptor, toll-like receptor 2, caspase 7, calmodulin, E3 ubiquitin-protein ligase, serine/threonine-protein kinase PRP4, glutathione S-transferase, and heat shock 70 kDa protein. MPs and P. lima poison mainly influence the expression of RNA transport, immune related gene, apoptosis, signal related gene, and antioxidant gene change. The combination of MPs and P. lima has a synergistic toxic effect. This study provides a new insights into its physiological and molecular responses of M. coruscus to MPs and P. lima toxic exposure.

The increasing big gap of carbon sink between the western and eastern Pacific in the last three decades - Guorong Zhong; Xuegang Li; Jinming Song; Baoxiao Qu; Fan Wang; Yanjun Wang; Bin Zhang; Detong Tian; Jun Ma; Huamao Yuan; Liqin Duan; Ning Li; et al. (Frontiers in Marine Science, 2022)
The Pacific Ocean is one of the important carbon sink regions, and there is a significant west-east difference in sea-air CO 2 flux. However, the influence of the long-standing greater CO 2 uptakes in the western Pacific than in the east and the dynamic change of this west-east difference remain unclear. In this paper, using the gridded surface ocean p CO 2 product constructed by the stepwise FFNN algorithm, we reported an increasing west-east CO 2 flux difference from 0.41 PgC yr -1 in 1992 to 0.73 PgC yr -1 in 2020. This increase was mainly attributed to the strengthening western Pacific carbon sink and relatively stable eastern Pacific carbon source. During El Nino events, the west-east CO 2 flux difference decreased significantly in a few years, and it then rose back rapidly when El Nino events ended. In addition, the increasing west-east difference in CO 2 uptakes during the last three decades did not lead to a higher acidification speed in the western surface temperate Pacific than the east. The greater CO 2 absorbed in the west was mainly transported to the deeper waters and caused a more significant carbon inventory change at 200-600 m than the eastern Pacific.

OECs Prevented Neuronal Cells from Apoptosis Partially Through Exosome-derived BDNF - Zhe Chen; Hong Fan; Zi-Yi Chen; Chao Jiang; Ming-Zhe Feng; Xin-Yu Guo; Hao Yang; Ding-Jun Hao (Journal of Molecular Neuroscience, 2022)

Association between gestational arsenic exposure and intrauterine growth restriction: the role of folate content - Fei-Xiang Xu; Xu Chen; Heng Zhang; Yi-Jun Fan; Ya-Ping Song; Jin-Wei Lv; Ya-Li Xie; Yichao Huang; Dao-Zhen Chen; Hua Wang; De-Xiang Xu (Environmental Science and Pollution Research, 2022)

Associations of bisphenol exposure with thyroid hormones in pregnant women: a prospective birth cohort study in China - Huishen Huang; Jun Liang; Peng Tang; Chuanxiang Yu; Haoran Fan; Qian Liao; Jinghua Long; Dongxiang Pan; Xiaoyun Zeng; Shun Liu; Dongping Huang; Xiaoqiang Qiu (Environmental Science and Pollution Research, 2022)

Preventive Effect and Mechanism of Anthocyanins from Aronia Melanocarpa Elliot on Hepatic Fibrosis Through TGF-β/Smad Signaling Pathway - Ruobing Hao; Jun Gao; Hongwei Liu; Chenjuan Zhang; Jinpeng Huang; Jungang Fan; Jie Wei (Cell Biochemistry and Biophysics, 2022)

Ice Nucleation of Cirrus Clouds Related to the Transported Dust Layer Observed by Ground-Based Lidars over Wuhan, China - Yun He; Fan Yi; Fuchao Liu; Zhenping Yin; Jun Zhou (Advances in Atmospheric Sciences, 2022)

Soil microbial communities and their co-occurrence networks in response to long-term Pb–Zn contaminated soil in southern China - Hongyang Xu; Bingqing Fu; Jiaqi Lei; Hui Kang; Jun Wang; Xinhao Huang; Fan Zhu (Environmental Science and Pollution Research, 2022)

Four sesquiterpenoids from the vegetable raw material Schisandra chinensis (Turcz.) Baill.: leaves and stems - Yong-Cheng Yang; Lu-Qi Liu; Kun-Jun Wang; Xue-Qing Zhang; San-Peng Fan; Xiao-Xu Gao; An-Hua Wang; Jing-Ming Jia; Chun-Wang Fu (Natural Product Research, 2022)

Acoustic Ray-Trace Correction for UUVs Cooperative Localization in Deep Ocean Applications - Zhenqiang Du; Hongzhou Chai; Zeyu Li; MinZhi Xiang; Fan Zhang; Jun Hui (Marine Geodesy, 2022)

CAF-derived midkine promotes EMT and cisplatin resistance by upregulating lncRNA ST7-AS1 in gastric cancer - Ke-Da Yang; Ying Wang; Fan Zhang; Qing-Ling Li; Bai-Hua Luo; De-Yun Feng; Zhi-Jun Zeng (Molecular and Cellular Biochemistry, 2022)

The recombinant subunit vaccine encapsulated by alginate‐chitosan microsphere enhances the immune effect against Micropterus salmoides rhabdovirus - Fei‐Fan Xu; Fu‐Yi Jiang; Guo‐Qing Zhou; Jun‐Yao Xia; Fei Yang; Bin Zhu (Journal of Fish Diseases, 2022)
The disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China. Vaccination was considered as a potential way to prevent and control this disease. As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA‐CS) are widely used in the development of oral vaccination for fish. Here, we prepared a king of alginate‐chitosan composite microsphere to encapsulate the second segment of MSRV glycoprotein (G2 protein) and then evaluated the immune effect of the microsphere vaccine on largemouth bass. Largemouth bass were vaccinated via intragastric immunization by different treatments (PBS, SA‐CS, G2 and SA‐CS‐G2). The results showed that a stronger immune response including serum antibody levels, immune‐related physiological indexes (acid phosphatase, alkaline phosphatase, superoxide dismutase and total antioxidant capacity) and the expression of immune‐related gene ( IgM、IL‐8、IL‐1β、CD4、TGF‐β、TNF‐α ) can be induced obviously with SA‐CS‐G2 groups compared with G2 groups when fish were vaccinated. Furthermore, fish were injected with a lethal dose of MSRV after immunization for 28 days, and the highest relative percentage survival (54.8%) was observed in SA‐CS‐G2 group (40 μg per fish), which is significantly higher than that of G2 group (25.8%). This study showed that alginate‐chitosan microspheres as the vaccine carrier can effectively improve the immune effect of oral vaccination and induce better immune protection effect against MSRV infection.

An “Eddy β-Spiral” mechanism for vertical velocity dipole patterns of isolated oceanic mesoscale eddies - Yinglin Hou; Fei-Fei Jin; Shan Gao; Jun Zhao; Kai Liu; Tangdong Qu; Fan Wang (Frontiers in Marine Science, 2022)
Oceanic eddies accompanied by a significant vertical velocity ( w ) are known to be of great importance for the vertical transport of various climatically, biologically or biogeochemically relevant properties. Using quasi-geostrophic w -thinking to extend the classic “ β -spiral” w -theory for gyre circulations to isolated and nearly symmetric oceanic mesoscale eddies, we propose that their w motion will be dominated by a strong east-west dipole pattern with deep ocean penetrations. Contrasting numerical simulations of idealized isolated eddies together with w -equation diagnostics confirm that the w -dipole is indeed dominated by the “eddy β -spiral” mechanism in the β -plane simulation, whereas this w -dipole expectedly disappears in the f -plane simulation. Analyses of relatively isolated warm and cold eddy examples show good agreement with the proposed mechanism. Our studies further clarify eddy vertical motions, have implications for ocean mixing and vertical transport, and inspire further studies.

Short-term effect of ambient temperature and ambient temperature changes on the risk of warts outpatient visits in Hefei, China: a retrospective time-series study - Bo Liu; Xin-Yu Fang; Yu-Lu Yan; Jun Wu; Xiao-Jie Lv; Jie Zhang; Liang-Wei Qi; Ting-Ting Qian; Yu-Yu Cai; Yin-Guang Fan; Dong-Qing Ye (Environmental Science and Pollution Research, 2022)

Effect of different carbon sources on sulfate reduction and microbial community structure in bioelectrochemical systems - Jing-jing Pan; Lu-yu Tan; Qing-qing Fan; Xiang-yang Cao; Jun Huang; Yu-kang Gu; Tian-ming Chen (Environmental Science and Pollution Research, 2022)

Triticonazole enantiomers induced enantioselective metabolic phenotypes in Fusarium graminearum and HepG2 cells - Yuan Kong; Chenyang Ji; Dong Guo; Rujian He; Meirong Zhao; Jun Fan (Environmental Science and Pollution Research, 2022)

Role of ocean dynamics in equatorial Pacific decadal variability - Yu Zhang; Shi-Yun Yu; Shang-Ping Xie; Dillon J. Amaya; Qihua Peng; Yu Kosaka; Xiaopei Lin; Jun-Chao Yang; Sarah M. Larson; Arthur J. Miller; Lei Fan (Climate Dynamics, 2022)

Siccirubricoccus soli sp. nov., a novel bacterial species isolated from Jiaozi Mountain soil - Guo-Xing Zhu; Ya-Jie Wu; Yan-Ru Cao; Bing-Jun Fan; Yu Jiao; Xiu-Li Hou; Zi-Chao Liu; Yue Zhang; Jiang-Bo He; Lian-Ming Liang (Antonie van Leeuwenhoek, 2022)

Identification of terrigenous and autochthonous organic carbon in sediment cores from cascade reservoirs in the upper stream of Pearl River and Wujiang River, southwest China: lignin phenol as a tracer - Li Gao; Xin Lin; Jun Fan; Ming Yang; Xueping Chen; Fushun Wang; Jing Ma (Acta Geochimica, 2022)

Transcriptome analysis and co‐expression network reveal the mechanism linking mitochondrial function to immune regulation in red crucian carp ( Carassius auratus red var) after Aeromonas hydrophila challenge - Ning‐Xia Xiong; Xu‐Ying Kuang; Zi‐Xuan Fang; Jie Ou; Shi‐Yun Li; Jia‐Hui Zhao; Jin‐Fang Huang; Ke‐Xin Li; Rou Wang; Lan‐Fen Fan; Sheng‐Wei Luo; Shao‐Jun Liu (Journal of Fish Diseases, 2022)
Aeromonas hydrophila is a common pathogen of freshwater fish. In this study, A. hydrophila infection was shown to cause tissue damage, trigger physiological changes as well as alter the expression profiles of immune‐ and metabolic‐related genes in immune tissues of red crucian carp (RCC). Transcriptome analysis revealed that acute A. hydrophila infection exerted a profound effect on mitochondrial oxidative phosphorylation linking metabolic regulation to immune response. In addition, we further identified cellular senescence, apoptosis, necrosis and mitogen‐activated protein kinase signal pathways as crucial signal pathways in the kidney of RCC subjected to A. hydrophila infection. These findings may have important implications for understanding modulation of immunometabolic response to bacterial infection.

Numerical Investigation on Temporal Evolution Behavior for Triad Resonant Interaction Induced by Steady Free-Surface Flow over Rippled Bottoms - Jun Fan; Aifeng Tao; Jinhai Zheng; Ji Peng (Journal of Marine Science and Engineering, 2022)
Investigating the wave hydrodynamics of free-surface flow over rippled bottoms is a continuing concern due to the existence of submarine multiple sandbars and ambient flow in coastal and estuarial areas. More attention to free-surface wave stimulation has been received from the perspective of resonant wave-wave interaction, which is an intensive way for wave energy transfer and a potential way for wave component generation. However, the basic behavior of the triad resonant interaction of this problem is still limited and unclear. In this study, the triad resonant interaction induced by steady free-surface flow over rippled bottoms is numerically investigated by means of the High-Order Spectral (HOS) method. By considering the interactions among free-surface waves, ambient current, and rippled bottoms, the numerical model is applied for this situation based on Zakharov equation with ambient flow term. The temporal evolution of the triad resonant wave amplitude has been numerically investigated and compared well with multiple-scale expansion perturbation theory. Specifically, the temporal evolution behaviors of all six triad resonant wave components are confirmed by both numerical simulation and nonlinear perturbation analysis.

Insights into the characteristics, adsorption and desorption behaviors of microplastics aged with or without fulvic acid - Xiulei Fan; Ya Xie; Shenwen Qian; Yuan Xiang; Qing Chen; YangYang Yang; Jiaqiang Liu; Jiankun Zhang; Jun Hou (Environmental Science and Pollution Research, 2022)

Identification and profiling of the community structure and potential function of bacteria from the fruiting bodies of Sanghuangporus vaninii - Yan-Jun Ma; Wei-Qian Gao; Xue-Tai Zhu; Wei-Bao Kong; Fan Zhang; Hong-Qin Yang (Archives of Microbiology, 2022)

Exploring the Spatial and Temporal Distribution of Frigate Tuna (Auxis thazard) Habitat in the South China Sea in Spring and Summer during 2015–2019 Using Fishery and Remote Sensing Data - Xingxing Zhou; Zuozhi Chen; Pengli Xiong; Yancong Cai; Jie Li; Peng Zhang; Jun Zhang; Miao Li; Jiangtao Fan (Fishes, 2022)
Frigate tuna Auxis thazard fishery is considered a potential marine resource in the open South China Sea (SCS). However, little is known about the spatial and temporal distribution of its habitat, and how this may respond to environmental changes. Using fish survey and remote sensing data from 2015–2019, we applied generalized additive models to identify relationships between environmental factors and the distribution of A. thazard in the SCS. To examine seasonal patterns in the habitat of A. thazard in the SCS, we generated a habitat suitability index model using environmental factors screened by generalized additive models. Results showed that A. thazard migrates from south to north in the SCS, and its suitable habitat is patchily distributed. Significant environmental factors affecting the habitat of A. thazard distribution were different in different seasons; we demonstrated A. thazard to be sensitive to Chl-a in spring (optimum 0.155, optimal range ~0.1252–0.1840), and in summer to be sensitive to SST (optimum 30.405, optimal range ~29.789–31.021) and SSH (optimum 0.741, optimal range ~0.618–0.864). Suitable habitat in spring occurs mainly in northeastern areas, while in summer it occurs mainly around the southeastern Nansha Islands. Compared with that in spring, the area of suitable habitat increases in summer, as does the habitat suitability index of the entire sea area. These results improve our understanding of environmental factors that affect the distribution of A. thazard habitat in the SCS, and provide a scientific basis for the development and management of A. thazard resources.

Archives of short-term fluid flow dynamics and possible influence of human activities at methane seeps: Evidence from high-resolution element geochemistry of chemosynthetic bivalve shells - Xudong Wang; Danling Fan; Steffen Kiel; Shanggui Gong; Qiangyong Liang; Jun Tao; Duofu Chen; Dong Feng (Frontiers in Marine Science, 2022)
The natural dynamics of fluid flow at methane seeps and increasingly human activities influence the biogeochemistry of the microenvironment and further determine the activity of the chemosynthetic communities within these ecosystems. However, ways to reconstruct short-term fluid flow dynamics and to decipher the influence of scientific exploration at seeps are limited. In this study, we present high-resolution trace elements/Ca ratios (Li/Ca, Mg/Ca, Ti/Ca, Mn/Ca, Co/Ca, Cu/Ca, Zn/Ca, Sr/Ca, Zr/Ca, Mo/Ca, Ba/Ca, Th/Ca and U/Ca ratios) from the shells of two species of chemosymbiotic bivalves (the thiotrophic vesicomyid clam Archivesica marissinica and the methanotrophic mussel Gigantidas haimaensis ) from the Haima cold seeps of the South China Sea. We found that the complex distribution patterns of some trace elements (Mg/Ca, Sr/Ca, Mo/Ca and U/Ca ratios) in G. haimaensis are largely controlled by mineral composition or age. The observation of Co/Ca and Ba/Ca ratios in both species indicate strong physiological and environmental control on the incorporation of trace elements during the biomineralization process. Besides, the distribution patterns of other trace elements provide information that can be used to discuss open issues such as the loss of trace elements after death of the bivalves, and the possible influence of human activities such as sediment disturbance. Overall, this study emphasizes the potential for using high-resolution element geochemistry of seep bivalve shells to reveal the physiological and environmental factors that control the growth of bivalves, and to elucidate the potential history of fluid discharge at cold seeps.

A Hybrid Logistic Regression: Gene Expression Programming Model and Its Application to Mineral Prospectivity Mapping - Fan Xiao; Weilin Chen; Jun Wang; Oktay Erten (Natural Resources Research, 2022)

Benefits of Endophytic Fungus Phomopsis liquidambaris Inoculation for Improving Mineral Nutrition, Quality, and Yield of Rice Grains Under Low Nitrogen and Phosphorus Condition - Meng-Jun Tang; Fan Lu; Yang Yang; Kai Sun; Qiang Zhu; Fang-Ji Xu; Wei Zhang; Chuan-Chao Dai (Journal of Plant Growth Regulation, 2022)

Knockdown of Chk1 inhibits proliferation and promotes apoptosis in mouse granulosa cells and its regulation mechanism by miR-15a and miR-16 - Xiao-Ming Liu; Fang Chen; Fan Zhang; Hai-Tao Xi; Jun-Zhao Zhao (In Vitro Cellular & Developmental Biology - Animal, 2022)

PLXDC2 enhances invadopodium formation to promote invasion and metastasis of gastric cancer cells via interacting with PTP1B - Bin Wu; Yan-xia Wang; Jun-jie Wang; Dong-fang Xiang; Meng-si Zhang; Ze-xuan Yan; Wen-ying Wang; Jing-ya Miao; Xi Lan; Jia-jia Liu; Zheng-yan Li; Chuan Li; et al. (Clinical & Experimental Metastasis, 2022)
Plexin-domain containing 2 (PLXDC2) has been reported as an oncoprotein in several human malignancies. However, its expression and roles in gastric cancer remain largely unclear. In this study, we found that PLXDC2 was highly expressed in gastric cancer tissues, and the expression levels were positively correlated with clinicopathological features, but negatively with the patients’ outcome. Cox regression analysis identified PLXDC2 as an independent prognostic indicator for the patients. Knockdown of PLXDC2 markedly suppressed the in vitro invasion and in vivo metastasis of gastric cancer cells, while overexpression of PLXDC2 resulted in opposite effects. Mechanistically, PLXDC2 enhanced the level of phosphorylated Cortactin (p-Cortactin) by physically interacting with protein tyrosine phosphatase 1B (PTP1B), an important dephosphorylase, to prevent its dephosphorylating of p-Cortactin, thereby promoting the formation of invadopodia. Collectively, our results indicate that PLXDC2 contributes to the invasion and metastasis of gastric cancer by inhibiting PTP1B to facilitate the invadopodium formation, and may serve as a potential prognostic biomarker and a therapeutic target for this disease.

Deep-layer motif method for estimating information flow between EEG signals - Denggui Fan; Hui Wang; Jun Wang (Cognitive Neurodynamics, 2022)

Evaluation of LAI Estimation of Mangrove Communities Using DLR and ELR Algorithms With UAV, Hyperspectral, and SAR Images - Bolin Fu; Jun Sun; Yeqiao Wang; Wenlan Yang; Hongchang He; Lilong Liu; Liangke Huang; Donglin Fan; Ertao Gao (Frontiers in Marine Science, 2022)
The high-precision estimation of mangrove leaf area index (LAI) using a deep learning regression algorithm (DLR) always requires a large amount of training sample data. However, it is difficult for LAI field measurements to collect a sufficient amount of sample data in mangrove wetlands. To tackle this challenge, this paper proposed an approach for expanding training samples and quantitatively evaluated the performance of estimating LAI for mangrove communities using Deep Neural Networks (DNN) and Transformer algorithms. This study also explored the effects of unmanned aerial vehicle (UAV) and Sentinel-2A multispectral, orbital hyper spectral (OHS), and GF-3 SAR images on LAI estimation of different mangrove communities. Finally, this paper evaluated the LAI estimation ability of mangrove communities using ensemble learning regression (ELR) and DLR algorithms. The results showed that: (1) the UAV images achieved the better LAI estimation of different mangrove communities (R 2 = 0.5974–0.6186), and GF-3 SAR images were better for LAI estimation of Avicennia marina with high coverage (R 2 = 0.567). The optimal spectral range for estimating LAI for mangroves in the optical images was between 650–680 nm. (2) The ELR model outperformed single base model, and produced the high-accuracy LAI estimation (R 2 = 0.5266–0.713) for different mangrove communities. (3) The average accuracy (R 2 ) of the ELR model was higher by 0.0019–0.149 than the DLR models, which demonstrated that the ELR model had a better capability (R 2 = 0.5865–0.6416) in LAI estimation. The Transformer-based LAI estimation of A. marina (R 2 = 0.6355) was better than the DNN model, while the DNN model produced higher accuracy for Kandelia candel (KC) (R 2 = 0.5577). (4) With the increase in the expansion ratio of the training sample (10–50%), the LAI estimation accuracy (R 2 ) of DNN and Transformer models for different mangrove communities increased by 0.1166–0.2037 and 0.1037–0.1644, respectively. Under the same estimation accuracy, the sample enhancement method in this paper could reduce the number of filed measurements by 20–40%.

High-throughput “read-on-ski” automated imaging and label-free detection system for toxicity screening of compounds using personalised human kidney organoids - Qizheng Wang; Jun Lu; Ke Fan; Yiwei Xu; Yucui Xiong; Zhiyong Sun; Man Zhai; Zhizhong Zhang; Sheng Zhang; Yan Song; Jianzhong Luo; Mingliang You; et al. (Journal of Zhejiang University-SCIENCE B, 2022)

Characteristics and influencing factors of frontal upwelling in the Yellow Sea in summer - Fan Sun; Fei Yu; Guangcheng Si; Jianfeng Wang; Anqi Xu; Jun Pan; Ying Tang (Acta Oceanologica Sinica, 2022)

Diversity and Structure of Demersal Fish Community Over the Northern Slope in the South China Sea - Jun Zhang; Kui Zhang; Yan-e Jiang; Yuan-jie Li; Jiang-tao Fan; Wen-ming Yu; Zuo-zhi Chen (Frontiers in Marine Science, 2022)
Three bottom trawl surveys over the northern continental slope in the South China Sea (18°50′–20°40′N, 112°50′–115°10′E) were carried out, in June 2015, March 2017 and September 2018, to investigate species composition, biodiversity and community structure of demersal fish. Surveys in 2015, 2017 and 2018 captured 97 fish species (representing 77 genera, 52 families, 26 orders), 108 fish species (representing 84 genera, 61 families, 19 orders) and 126 fish species (representing 105 genera, 74 families, 25 orders), respectively. Three surveys captured a total of 252 fish species, representing 164 genera, 97 families, 30 orders. Perciformes dominated. Species richness in station linking shallow continental shelf with deep slope was the lowest among stations. In three surveys, 16 species occurred in the catches of three surveys, accounting for 6.35% of all species. Species replacement rate between stations showed a significant linear relationship with the depth difference and latitude difference. Margalef’s species richness index ( D ), Shannon–Weiner diversity index ( H’ ) and Pielou’s evenness index ( J’ ) among stations ranged 2.65–6.74, 1.02–4.15 and 0.28–1.14, respectively. Differences of D , H ’ and J ’ were insignificant among seasons. There were significant positive linear relations between H’ and J’ and latitude. D , H’ and J’ decreased with increasing sampling depth, however the relations were not significant. Based on multivariate statistical analysis, fish community at species level was divided into five groups with average dissimilarities of 95.69%–99.96%. In terms of genus and family, average dissimilarities among groups were more than 88.11% and 82.69%. There were significant differences in species composition between depths, but no significant differences between seasons and temperatures, as well as in genus and family composition.

Enantioselective acute toxicity, oxidative stress effects, neurotoxicity, and thyroid disruption of uniconazole in zebrafish (Danio rerio) - Dong Guo; Rujian He; Lulu Luo; Weiguang Zhang; Jun Fan (Environmental Science and Pollution Research, 2022)

Astragalus Polysaccharides Reduce High-glucose-induced Rat Aortic Endothelial Cell Senescence and Inflammasome Activation by Modulating the Mitochondrial Na+/Ca2+ Exchanger - Xin-Yu Miao; Xiao-Xiao Zhu; Zhao-Yan Gu; Bo Fu; Shao-Yuan Cui; Yuan Zu; Ling-Jun Rong; Fan Hu; Xiang-Mei Chen; Yan-Ping Gong; Chun-Lin Li (Cell Biochemistry and Biophysics, 2022)

Anti-hyperglycaemic effect of labdane diterpenes isolated from the rhizome of Amomum maximum Roxb., an edible plant in Southwest China - Chuan-Li Lu; Li-Ning Wang; Ya-Jun Li; Qing-Fei Fan; Qing-Hua Huang; Jun-Jia Chen (Natural Product Research, 2022)

Four new triterpene glucosides from Salacia cochinchinensis Lour - Lu Gao; Li-Kun Duan; Jin-E Feng; Yun-Tao Jiang; Jun Gao; Jun-Ting Fan; Rong Dai; Zhi-Yong Jiang (Natural Product Research, 2022)

Marker-assisted introgression of Xa39 improve rice resistance to five Xanthomonas oryzae pv. oryzae strains - Yingyao Shi; Wei Zeng; Junping Xie; Fan Zhang; Dalong Zhuo; Lingling Gao; Mingfu Zhao; Xiaorong Shi; Minghui Xu; Zhenzhen Zheng; Zhiqi Hao; Hongyan Yuan; et al. (Journal of Plant Pathology, 2022)

The solar wind plasma upstream of Mars observed by Tianwen-1: Comparison with Mars Express and MAVEN - Kai Fan; Limei Yan; Yong Wei; Aibing Zhang; Linggao Kong; Markus Fränz; Fei He; Lihui Chai; Chongjing Yuan; Yuqi Wang; Jun Zhong; Zhaojin Rong; et al. (Science China Earth Sciences, 2022)

Experimental Study on the Disintegration Properties of Red Sandstone - Bao-Jie Fan; Fu-jun Zhao; Zong-tang Zhang; Yong-hong Liu (Geotechnical and Geological Engineering, 2022)

Petrogenesis and tectonic implications of Late Triassic dikes from the Suolun within the central Great Xing’an Range, NE China: constraints from geochronology and geochemistry - Yan Li; Hai-yin Xi; Feng-Jun Nie; Yao Zhang; Yue-ye Fan; Dong-yu Fang; Zhao-Bin Yan (Arabian Journal of Geosciences, 2022)

Investigation on Natural Infection of Covert Mortality Nodavirus in Large Yellow Croaker, Larimichthys crocea - Tingting Xu; Yuding Fan; Tianchang Jia; Chong Wang; Wei Wang; Jun Li; Qingli Zhang; Cuiluan Yao (Frontiers in Marine Science, 2022)
Covert mortality nodavirus (CMNV) recently became more prevalent, severely affecting farmed shrimps, and also other invertebrates and teleost fish, in the coastal areas of China. For better understanding of its prevalence and susceptibility of large yellow croaker Larimichthys crocea to CMNV, an epidemiological survey was carried out in the main producing areas (Ningbo, Zhejiang, China, and Ningde, Fujian, China) and its offshore feeding grounds in the Southern Yellow Sea. The collected cultured L. crocea individuals showed clinical symptoms such as anorexia and abnormal swimming and diagnosed for CMNV infection by using RT-nPCR assay. The positive rates for CMNV in the collected L. crocea samples from Ningbo, Ningde, and the Yellow Sea were 14.29% (4/28), 20.00% (7/35), and 16.67% (1/6), respectively. Furthermore, CMNV diagnosis using TaqMan probe-based reverse transcription quantitative PCR (TaqMan RT-qPCR) yielded positive rates of 25.00% (7/28), 22.86% (8/35), and 16.67% (1/6) respectively in the above-mentioned samples, and with a range of 12.73–3,108.33 of CMNV copy numbers/μg total RNA. Phylogenetic tree analysis based on the RNA-dependent RNA polymerase (RdRp) and capsid protein genes showed that CMNV isolates from L. crocea samples were clustered tightly with the original isolate of CMNV from Penaeus vannamei . The histopathological studies indicated that severe cellular necrosis occurred in the heart, liver, spleen, eye, and gill of naturally infected fish. Stronger positive signals for CMNV-specific probes appeared in the necrotic cells and tissues in the in situ hybridization (ISH) analysis. Transmission electron microscopy (TEM) revealed the presence of numerous 30 nm diameter CMNV-like viral particles. The purified CMNV suspension could cause a significant cytopathic effect (CPE) in epithelioma papilloma cyprini (EPC) cells and resulted in the formation of typical inclusion bodies, and also visible CMNV particles around the lysed EPC cells under the TEM. Taken together, all results of this study demonstrated that L. crocea is susceptible to CMNV. The prevalence of CMNV and its potential impacts on the wild population of L. crocea see the need for further investigations.

Mass transport of a mesoscale eddy in the South China Sea identified by a simulated passive tracer - Jun Zhao; Fan Wang; Shan Gao; Yinglin Hou; Kai Liu (Journal of Oceanology and Limnology, 2022)

Integrative testing device for investigating the hydro-mechanical behavior of highly expansive clay - Yun-zhi Tan; Fan Peng; Hui Li; Hua-jun Ming; De-an Sun (Arabian Journal of Geosciences, 2022)

Preface to the Special Issue: Climate Change and Variability of Tropical Cyclone Activity - Liguang Wu; Bin Wang; Johnny C. L. Chan; Kyung-Ja Ha; Il-Ju Moon; Jun Matsumoto; Zhemin Tan; Ke Fan (Advances in Atmospheric Sciences, 2022)

Identification of A-to-I RNA editing profiles and their clinical relevance in lung adenocarcinoma - Cheng Wang; Mingtao Huang; Congcong Chen; Yuancheng Li; Na Qin; Zijian Ma; Jingyi Fan; Linnan Gong; Hui Zeng; Liu Yang; Xianfeng Xu; Jun Zhou; et al. (Science China Life Sciences, 2022)

Paracoccus shandongensis sp. nov., Isolated from Activated Sludge - Xiao-Fan Gong; Fang Wang; Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Zong-Jun Du; Qiang Li (Current Microbiology, 2022)

Infestation and distribution of mites on the Yunnan red-backed vole (Eothenomys miletus) in Yunnan Province of southwest China between 2001 and 2015 - Rong Xiang; Xian-Guo Guo; Tian-Guang Ren; Cheng-Fu Zhao; Rong Fan; Zhi-Wei Zhang; Ke-Yu Mao; Pei-Ying Peng; Xiao-Bin Huang; Ti-Jun Qian (Biologia, 2022)

Effect of feed restriction on the intestinal microbial community structure of growing ducks - Jun-peng Li; Qi-fan Wu; Sheng-chao Ma; Jian-mei Wang; Bin Wei; Yang Xi; Chun-chun Han; Liang Li; Hua He; He-he Liu (Archives of Microbiology, 2022)

Mesorhizobium xinjiangense sp. nov., isolated from rhizosphere soil of Alhagi sparsifolia - Dong Meng; Yu-Ling Liu; Jun-Jie Zhang; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Heng Meng; Zong-Jun Du; Wei-Min Li; Qiang Li (Archives of Microbiology, 2022)

Comprehensive evaluation and analysis of the salinity stress response mechanisms based on transcriptome and metabolome of Staphylococcus aureus - Ying Feng; Dizhou Gu; Ziyan Wang; Chenyang Lu; Jingfeng Fan; Jun Zhou; Rixin Wang; Xiurong Su (Archives of Microbiology, 2022)

Environmental drivers of phytoplankton crops and taxonomic composition in northeastern Antarctic Peninsula adjacent sea area - Yubin Feng; Dong Li; Jun Zhao; Zhengbing Han; Jianming Pan; Gaojing Fan; Haisheng Zhang; Ji Hu; Haifeng Zhang; Jiaqi Wu; Qiuhong Zhu (Acta Oceanologica Sinica, 2022)

Gisenoside Rg1 attenuates cadmium-induced neurotoxicity in vitro and in vivo by attenuating oxidative stress and inflammation - Teng-Teng Ren; Jia-Ying Yang; Jun Wang; Sheng-Rui Fan; Rongfeng Lan; Xiao-Yan Qin (Inflammation Research, 2021)

Effect of lgals3a on embryo development of zebrafish - Kan Chen; Yuqi Fan; Jun Gu; Zhihua Han; Yue Wang; Lin Gao; Huasu Zeng; Chengyu Mao; Changqian Wang (Transgenic Research, 2021)

Soil bacterial communities interact with silicon fraction transformation and promote rice yield after long-term straw return - Alin Song; Zimin Li; Yulin Liao; Yongchao Liang; Enzhao Wang; Sai Wang; Xu Li; Jingjing Bi; Zhiyuan Si; Yanhong Lu; Jun Nie; Fenliang Fan (Soil Ecology Letters, 2021)

Origin of the Low δ18O Signals in Zircons from the Early Cretaceous A-Type Granites in Eastern China: Evidence from the Kulongshan Pluton - Wenbo Fan; Neng Jiang; Mingguo Zhai; Jun Hu (Journal of Earth Science, 2021)

Full waveform inversion based on deep learning and optimal nearly analytic discrete method - Lu Fan; Zhou Yan-Jie; He Xi-Jun; Ma Xiao; Huang Xue-Yuan (Applied Geophysics, 2021)

Improvement of farmland drainage calculation method under environmental change in Huaibei plain * - Jun‐feng Wang; Mei Zhu; Zhen‐long Wang; Tian‐tong Zhang; Yin‐fan Qi; Ling‐ling Zhu (Irrigation and Drainage, 2021)
Changes and new thoughts are vital if the farmland drainage method in the Huabei Plain is to be improved. In this article, drainage flow was chosen as the research object. Based on long‐series precipitation data, the spatial distribution of precipitation was analysed. The peak value relation index ( m ) was either adjusted or unadjusted in contrast calculations with the empirical formula and the average draining formula. The adjustment rationality and adjustment range of m were researched. Results of calculations were analysed and used to improve the applicability of the empirical formula. The spatial distribution of precipitation showed a decreasing trend from south‐west to north‐east. Before adjustment, the result of the empirical formula was equivalent to the flow of 1 day of draining water. After adjusting m to 0.84–0.87, the result was equivalent to the flow of 1.5 days of draining water. With the decrease of rainfall frequency, the drainage flow of the average draining formula was greater than that of the empirical formula and the ratio was 1.13 times when the runoff depth was 50 mm. m can be selected from 0.84 to 0.87 for calculating drainage flow in the Huabei Plain by using the empirical formula and has a direct ratio with precipitation.

Euphanoids A and B, two new lathyrane diterpenoids with nitric oxide (NO) inhibitory activity from Euphorbia kansuensis - Xue-Long Yan; Run-Zhu Fan; Jun Sang; Xing-Lin Xie; Gui-Hua Tang; Sheng Yin (Natural Product Research, 2021)

Linking circular intronic RNA degradation and function in transcription by RNase H1 - Xiang Li; Jia-Lin Zhang; Yun-Ni Lei; Xiao-Qi Liu; Wei Xue; Yang Zhang; Fan Nan; Xiang Gao; Jun Zhang; Jia Wei; Li Yang; Ling-Ling Chen (Science China Life Sciences, 2021)

Mutation of the sixth amino acid of the Rep protein has no effect on porcine circovirus 2b but enhances porcine circovirus 2d replication in vitro - Xiaoyan Wu; Shuo Wang; Changxun Xin; Chen Li; Jianli Shi; Zhe Peng; Chang Liu; Hong Han; Ying Yang; Yao Tian; Jiaxin Li; Shaojian Xu; et al. (Archives of Virology, 2021)

A landslide in Heifangtai, northwest of the Chinese Loess Plateau: triggered factors, movement characteristics, and failure mechanism - Jia-xu Kong; Jian-qi Zhuang; Jie-wei Zhan; Zheng-wei Bai; Yan-qiu Leng; Peng-hui Ma; Jian-bing Peng; Zuo-peng Wang; Tian-feng Gu; Jia-xing Sun; Fan-chen Zhang; Yuan-jun Xu; et al. (Landslides, 2021)

Food-grade γ-aminobutyric acid production by immobilized glutamate decarboxylase from Lactobacillus plantarum in rice vinegar and monosodium glutamate system - Li-Li Yao; Jia-Ren Cao; Chang-Jiang Lyu; Fang-Fang Fan; Hong-Peng Wang; Hong-Wei Cao; Jun Huang; Le-He Mei (Biotechnology Letters, 2021)

Effects of acute hypoxia stress on hemato-biochemical parameters, oxidative resistance ability, and immune responses of hybrid yellow catfish (Pelteobagrus fulvidraco × P. vachelli) juveniles - Missinhoun Dagoudo; Jun Qiang; Jin-Wen Bao; Yi-Fan Tao; Hao-Jun Zhu; Ezra Mutebi Tumukunde; Tlou Kevin Ngoepe; Pao Xu (Aquaculture International, 2021)

Vertical Fine-Scale Distribution of Calanus sinicus in the Yellow Sea Cold Water Mass During the Over-Summering Process - Jun Pan; Fangping Cheng; Fei Yu; Yongqiang Shi; Fan Sun; Guangcheng Si; Chuanjie Wei; Xinyuan Diao; Yongfang Zhao (Frontiers in Marine Science, 2021)
Calanus sinicus , a temperate copepod with a lethal temperature >27°C, is one of the key species in Chinese coastal marine ecosystems. The C. sinicus population increases in spring and declines in early summer annually due to increasing water temperature. Numerous C. sinicus individuals then congregate in the Yellow Sea Cold Water Mass (YSCWM) and remain under the thermocline from early summer to early autumn. Development and reproduction is halted in this cold and foodless bottom water and they avoid ascending to the hot surface water, which is regarded as an over-summering strategy. Based on discrete water sampling approaches, previous studies demonstrated that higher chlorophyll a (Chl a) levels appeared in the mixed hot surface water layer; however, the subsurface chlorophyll a maximum layer (SCML) has seldom been described. In the present study, various probes and a visual plankton recorder (VPR) were used to determine the fine vertical distributions of environmental factors and C. sinicus . VPR observations showed the ecological responses in fine scale and indicated that few C. sinicus individuals ascend at night, the main population preferred to remain below the SCML all day long. The results demonstrated that a constant thin SCML existed in the YSCWM area, and that the SCML location coincided with or was beneath the thermocline and halocline layers, where the temperature was suitable for C. sinicus . The relationship between abundance and Chl a, showed the diel vertical migration trend of C. sinicus to feed at night in the YSCWM area. In addition to temperature as a main influencing factor, dissolved oxygen concentrations and column depth were also influencing factors. Therefore, in addition to avoiding high surface temperature, energy supplement may be an important driving force confining the diel vertical migration of C. sinicus in the Yellow Sea in summer.

Octamer transcription factor-1 induces the Warburg effect via up-regulation of hexokinase 2 in non-small cell lung cancer - Zhen Li; Jin Su; Mingming Sun; Jiaqi Song; Huanran Sun; Jun Fan; Guo Chen; Changliang Shan; Qi Qi; Shuai Zhang (Molecular and Cellular Biochemistry, 2021)

Gas permeability evolution of granite under confining pressure unloading tests - Dawei Hu; Jun Li; Hui Zhou; Jingjing Lu; Dongdong Ma; Fan Zhang (European Journal of Environmental and Civil Engineering, 2021)

Flume Experiments on Energy Conversion Behavior for Oscillating Buoy Devices Interacting with Different Wave Types - Shufang Qin; Jun Fan; Haiming Zhang; Junwei Su; Yi Wang (Journal of Marine Science and Engineering, 2021)
Oscillating buoy device, also known as point absorber, is an important wave energy converter (WEC) for wave energy development and utilization. The previous work primarily focused on the optimization of mechanical design, buoy’s array configuration and the site selection with larger wave energy density in order to improve the wave energy generation performance. In this work, enlightened by the potential availability of Bragg reflection induced by multiple submerged breakwaters in nearshore areas, we investigate the energy conversion behavior of oscillating buoy devices under different wave types (traveling waves, partial and fully standing waves) by flume experiments. The localized partial standing wave field is generated by the Bragg resonance at the incident side of rippled bottoms. Furthermore, the fully standing wave field is generated by the wave reflection of vertical baffle installed in flume. Then the wave power generation performance is discussed under the conditions with the same wave height but different wave types. The experimental measurements show that the energy conversion performance of the oscillating buoy WEC could be improved under the condition of standing waves when compared with traveling waves. This work provides the experimental comparison evidence of wave energy conversion response of oscillating buoy devices between travelling waves and standing (fully or partial) wave conditions.

Paracoccus binzhouensis sp. nov., isolated from activated sludge - Fang Wang; Xiao-Fan Gong; Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Zong-Jun Du; Qiang Li (Archives of Microbiology, 2021)

The Effects on Water Particle Velocity of Wave Peaks Induced by Nonlinearity under Different Time Scales - Aifeng Tao; Shuya Xie; Di Wu; Jun Fan; Yini Yang (Journal of Marine Science and Engineering, 2021)
The water particle velocity of the wave peaks is closely related to the wave load borne by offshore structures. It is of great value for marine disaster prevention to study the water particle velocity of nonlinear extreme waves represented by Freak waves. This study applies the High-order Spectral Method (HOS) numerical model to analyze the characteristics and influencing factors of the water particle velocity of Freak wave peak with two different generation mechanisms under the initial condition of a weakly modulated Stokes wave train. Our results show that the water particle velocity of the wave peak increases linearly with wave height and initial wave steepness in the evolution stage of modulation instability. While in the later stage, the relationship becomes exponential. Under the condition of similar wave heights, the deformation degrees of Freak waves with different generation mechanisms are distinct, the deformation degree of modulation instability stage is smaller than that of the later stage. The water particle velocity of the wave peaks increases with the deformation degrees. Furthermore, the correlation between wave peak height and water particle velocity is a quadratic function. This provides a theoretical basis for further understanding of nonlinear waves and the prediction of marine disasters.

The interaction of MYB, bHLH and WD40 transcription factors in red pear (Pyrus pyrifolia) peel - Daolei Cui; Shuxin Zhao; Huini Xu; Andrew C. Allan; Xiaodong Zhang; Lei Fan; Limei Chen; Jun Su; Quan Shu; Kunzhi Li (Plant Molecular Biology, 2021)

Microwave irradiation coupled with zero-valent iron that enhances the composite geopolymerization of chromite ore processing residue and its mechanisms - Tao Huang; Zhen-Xing Cao; Xin-Chuan Fan; Jun-Xun Jin; Chun-Hai Yang; Long-Fei Liu; Shu-Wen Zhang (Environmental Science and Pollution Research, 2021)

Using seismic sedimentology in delineating a distributary channel type shallow-water lacustrine delta: first member of the Cretaceous Yaojia Formation in Changling area, South of Songliao Basin - Jun Wang; Kai Zeng; Bowen Wu; Jianzheng Ji; Zhidong Bao; Bin Cheng; Hongjing Zhang; Ping Xiong; Fan Diao (Arabian Journal of Geosciences, 2021)

Unraveling Street-Level Air Pollution upon a Pivotal City of Yangtze River Delta, China - Rui Feng; Han Gao; Zhuo Wang; Kun Luo; Jian-ren Fan; Hui-jun Zheng (Aerosol Science and Engineering, 2021)

Recent advances in continuous extraction of bioactive ingredients from food-processing wastes by pulsed electric fields - Jun Xi; Zongming Li; Yang Fan (Critical Reviews in Food Science and Nutrition, 2021)

Fluvastatin attenuated ischemia/reperfusion-induced autophagy and apoptosis in cardiomyocytes through down-regulation HMGB1/TLR4 signaling pathway - Hua-Sheng Ding; Jun Yang; Jian Yang; Xin Guo; Yan-Hong Tang; Yan Huang; Zhen Chen; Zhi-Xing Fan; Cong-Xin Huang (Molecular Biology Reports, 2021)

First report of grapevine Cabernet Sauvignon reovirus from grapevines in China - Xu Dong Fan; Ya Feng Dong; Zun Ping Zhang; Fang Ren; Guo Jun Hu (Journal of Plant Pathology, 2021)

Bjerkandera adusta M1 inhibits the growth of Fusarium oxysporum f. sp. conglutinans and fusarium wilt incidence in Brassica napus L. - Xiao Feng; Su-Ping Li; Yi-Fan Lu; Jing-Jie Zhang; Yun-Yun Zhu; Yong Li; Hong-Jun Yang; Xin-Hua He (Journal of Plant Pathology, 2021)

Cryostructures and ground ice content in ice-rich permafrost area of the Qinghai-Tibet Plateau with Computed Tomography Scanning - Xing-wen Fan; Zhan-ju Lin; Ze-yong Gao; Xiang-lian Meng; Fu-jun Niu; Jing Luo; Guo-an Yin; Fu-jun Zhou; Ai-yu Lan (Journal of Mountain Science, 2021)

Experimental validation of a new semi-empirical impact force model of the dry granular flow impact against a rigid barrier - Yuan-Jun Jiang; Xiao-Yi Fan; Li-Jun Su; Si-you Xiao; Jing Sui; Rui-Xiao Zhang; Yue Song; Zhi-Wen Shen (Landslides, 2021)

Chelativorans alearense sp. nov., A Novel Bacterial Species Isolated From Soil in Alear, China - Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Wei-Min Li; Zong-Jun Du; Qiang Li (Current Microbiology, 2021)

Chelativorans xinjiangense sp. nov., a novel bacterial species isolated from soil in Xinjiang, China - Dong Meng; Yu-Ling Liu; Peng-Fei Gu; Xiang-Yu Fan; Zhao-Song Huang; Yan Ji; Wei-Min Li; Zong-Jun Du; Qiang Li (Archives of Microbiology, 2021)

Propylenella binzhouense gen. nov., sp. nov. isolated from activated sludge, and proposal of Propylenellaceae fam. nov. - Yu-Ling Liu; Dong Meng; Fang Wang; Xiao-Fan Gong; Peng-Fei Gu; Xiang-Yu Fan; Zong-Jun Du; Ji-Dong Zou; Qiang Li (Antonie van Leeuwenhoek, 2021)

Probiotics, prebiotics, and synbiotics for the improvement of metabolic profiles in patients with chronic kidney disease: A systematic review and meta-analysis of randomized controlled trials - Hui Juan Zheng; Jing Guo; Qiuhong Wang; Liansheng Wang; Yahui Wang; Fan Zhang; Wei-Jun Huang; Wenting Zhang; Wei Jing Liu; Yaoxian Wang (Critical Reviews in Food Science and Nutrition, 2021)

Climate and Human-Driven Variability of Summer Hypoxia on a Large River-Dominated Shelf as Revealed by a Hypoxia Index - Kui Wang; Wei-Jun Cai; Jianfang Chen; David Kirchman; Bin Wang; Wei Fan; Daji Huang (Frontiers in Marine Science, 2021)
Coastal hypoxia has become common especially in large river dominated coastal ecosystems. To better quantify the severity of hypoxia and the contribution of hypoxia drivers, we applied principal component analysis (PCA) on observable properties from eight summer hypoxia events in the East China Sea and defined the first principal component as the hypoxia index (HI). Multiple linear regression showed that the HI significantly correlated with three direct hypoxia drivers including water column stratification, subsurface water residence time, and respiration rates, which accounted for 5.7, 55.3, and 34.5%, respectively, of the total variance of PCA derived HI. We further reconstructed the HI over the past 60 years using available long-term data of stratification, model-derived residence times and respiration rates. The results show that summer hypoxia has become more severe since the 1960s. ENSO and global warming may have exacerbated hypoxia by affecting the river discharge, resulting in freshening in the plume-impacted shelf area, while anthropogenic activities may have exacerbated hypoxia by elevating fluvial nutrient concentrations, resulting in higher respiration rates. In addition, warming of the bottom water from the Kuroshio Current accounts for an additional increasing rate for HI, which made hypoxia more severe by means of decreasing oxygen solubility. Overall, our results indicate that stratification, water residence and oxygen solubility resulting from climate change can explain about 80% while higher respiration resulting from higher nutrient inputs can explain about 20% of the variation in the severity of hypoxia during the past half century.

First report of Chaetomella raphigera causing brown spot on Eucalyptus urophylla × E. grandis in China - Xiu-Xiu Cao; Ji-Guang Wei; Jian-Gan Hou; Chun-Li Fan; Ji Luo; Yao-Jun Wu; Xiu-Hao Yang; Ji-Tong Luo; Xiao-Bing Yang (Journal of Plant Pathology, 2021)

First report of grapevine enamovirus 1 in grapevine in China - Fang Ren; Zun Ping Zhang; Xu Dong Fan; Guo Jun Hu; Ya Feng Dong (Journal of Plant Pathology, 2021)

Correlation of exosomal microRNA clusters with bone metastasis in non-small cell lung cancer - Xiao-Rong Yang; Can Pi; Ruoying Yu; Xiao-Jun Fan; Xiao-Xiao Peng; Xu-Chao Zhang; Zhi-Hong Chen; Xue Wu; Yang Shao; Yi-Long Wu; Qing Zhou (Clinical & Experimental Metastasis, 2021)
20–40% of lung cancer patients develop bone metastasis (BM) with significantly decreased overall survival. Currently, BM is mainly diagnosed by computerized tomography (CT) scan or magnetic resonance imaging (MRI) when symptom develops. Novel biomarkers with higher prediction value of BM are needed. Plasma-derived exosomal microRNAs had been isolated and sequenced of total 30 non-small cell lung cancer (NSCLC) patients including 16 with bone metastasis and 14 without bone metastasis. Hierarchical clustering based on the total miRNA profile can clearly separate cancer patients and healthy individuals (H), but not patients with (BM +) or without (BM−) BM. Weight Co-expression network of miRNAs (WGCNA) analyses identified three consensus clusters (A, B, C) of highly correlated miRNAs, among which cluster B (144 miRNAs) showed significantly differential expression in lung cancer patients, especially in BM + group. Pathway analysis of cluster B miRNAs revealed enrichment in metabolic pathways that may involve in preconditioning of the metastatic niche. Three differentially expressed miRNAs between BM + and BM− patients within cluster B were identified as miR-574-5p, a suppressor of Wnt/β-catenin pathway, was down-regulated, while miR-328-3p and miR-423-3p, two activators of the same pathway, were up-regulated in BM + patients. Cluster A miRNAs (n = 49) also showed trend of upregulation in BM + patients. Interestingly, pathway analysis indicated that 43 of them are associated with chromosome14, which has been suggested to promote epithelial-mesenchymal transition (EMT) and bone metastasis.

Functional connectivity of thalamus in children with primary nocturnal enuresis: results from a resting-state fMRI study - Anyi Zhang; Lichi Zhang; Mengxing Wang; Yiwen Zhang; Fan Jiang; Xingming Jin; Xiaoxia Du; Jun Ma (Brain Imaging and Behavior, 2021)

Identification through fine mapping and verification using CRISPR/Cas9-targeted mutagenesis for a minor QTL controlling grain weight in rice - Aye Nyein Chan; Lin-Lin Wang; Yu-Jun Zhu; Ye-Yang Fan; Jie-Yun Zhuang; Zhen-Hua Zhang (Theoretical and Applied Genetics, 2021)
Key message A minor QTL for grain weight in rice, qTGW1.2b , was fine-mapped. Its casual gene OsVQ4 was confirmed through CRISPR/Cas9-targeted mutagenesis, exhibiting an effect that was larger than the original QTL effect. Abstract The CRISPR/Cas system exhibits a great potential for rice improvement, but the application was severely hindered due to insufficient target genes, especial the lack of validated genes underlying quantitative trait loci having small effects. In this study, a minor QTL for grain weight, qTGW1.2b , was fine-mapped into a 44.0 kb region using seven sets of near isogenic lines (NILs) developed from the indica rice cross (Zhenshan 97) 3 /Milyang 46, followed by validation of the causal gene using CRISPR/Cas9-targeted mutagenesis. In the NIL populations, 1000-grain weight of the Zhenshan 97 homozygous lines decreased by 0.9–2.0% compared with the Milyang 46 homozygous lines. A gene encoding VQ-motif protein, OsVQ4 , was identified as the candidate gene based on parental sequence differences. The effect of OsVQ4 was confirmed by creating CRISPR/Cas9 knockout lines, whose 1000-grain weight decreased by 2.8–9.8% compared with the wild-type transgenic line and the recipient. These results indicate that applying genome editing system could create novel alleles with large phenotypic variation at minor QTLs, which is an effective way to validate causal genes of minor QTLs. Our study establishes a strategy for cloning minor QTLs, which could also be used to identify a large number of potential target genes for the application of CRISPR/Cas system.

Effects of Different Component Contents of Colistin Methanesulfonate on the Pharmacokinetics of Prodrug and Formed Colistin in Human - Ya-Xin Fan; Yuan-Cheng Chen; Yi Li; Ji-Cheng Yu; Xing-Chen Bian; Xin Li; Wan-Zhen Li; Bei-Ning Guo; Hai-Lan Wu; Xiao-Fen Liu; Yu Wang; Xiao-Yong Xu; et al. (Pharmaceutical Research, 2021)

Solidification of loess using microbial induced carbonate precipitation - Xiao-jun Liu; Jin-yue Fan; Jing Yu; Xin Gao (Journal of Mountain Science, 2021)

CD40 induces an antimicrobial response against the intracellular pathogen Streptococcus agalactiae in Nile tilapia, Oreochromis niloticus - Hongli Xia; Huimin Fan; Meng Long; Jun Cheng; Wenjie Chen; Dapeng Yu; Liqun Xia; Yishan Lu (Journal of Fish Diseases, 2021)
Streptococcus agalactiae is a Gram‐positive facultative intracellular bacterium that leads to severe economic loss of tilapia worldwide. Previous studies demonstrated that CD40 contributes to host protection against intracellular injection. In this study, CD40 was characterized from Nile tilapia ( Oreochromis niloticus ), named OnCD40. Sequence analysis showed that open reading frame of OnCD40 was 933 bp, containing a single peptide, a transmembrane domain and four cysteine‐rich domains. The qRT‐PCR revealed that OnCD40 was expressed in all examined tissues with the most abundant ones in spleen and thymus. After S. agalactiae stimulation, the expression of OnCD40 was significantly induced in most of the detected organs. Moreover, OnCD40‐overexpressing fish elicited significant protection against subsequent S. agalactiae challenge; approximately 10000‐fold fewer bacteria were detected in spleen of OnCD40‐overexpressing fish in comparison with control fish. Thus, CD40 had protecting function in Nile tilapia against intracellular pathogens.

Adakitic rocks at convergent plate boundaries: Compositions and petrogenesis - Qiang Wang; Lulu Hao; Xiuzheng Zhang; Jinsheng Zhou; Jun Wang; Qiwei Li; Lin Ma; Long Zhang; Yue Qi; Gongjian Tang; Wei Dan; Jingjing Fan (Science China Earth Sciences, 2020)

The origin of arc basalts: New advances and remaining questions - Yigang Xu; Qiang Wang; Gongjian Tang; Jun Wang; Hongyan Li; Jinsheng Zhou; Qiwei Li; Yue Qi; Pingping Liu; Lin Ma; Jingjing Fan (Science China Earth Sciences, 2020)

Finite element investigation on the dynamic mechanical properties of low-frequency vibrations on human L2–L3 spinal motion segments with different degrees of degeneration - Ruoxun Fan; Jie Liu; Jun Liu (Medical & Biological Engineering & Computing, 2020)

Evaluation of crustal inhomogeneity parameters in the southern Longmenshan fault zone and adjacent regions - Xiao-Ping Fan; Yi-Cheng He; Cong-Jie Yang; Jun-Fei Wang (Journal of Seismology, 2020)
Broadband teleseismic waveform data from 13 earthquakes recorded by 70 digital seismic stations were selected to evaluate the inhomogeneity parameters of the crustal medium in the southern Longmenshan fault zone and its adjacent regions using the teleseismic fluctuation wavefield method. Results show that a strong inhomogeneity exists beneath the study region, which can be divided into three blocks according to its structure and tectonic deformation features. These are known as the Sichuan-Qinghai Block, the Sichuan-Yunnan Block, and the Mid-Sichuan Block. The velocity fluctuation ratios of the three blocks are approximately 5.1%, 3.6%, and 5.1% in the upper crust and 5.1%, 3.8%, and 4.9% in the lower crust. The inhomogeneity correlation lengths of the three blocks are about 10.1 km, 14.0 km, and 10.7 km in the upper crust and 11.8 km, 17.0 km, and 11.8 km in the lower crust. The differences in the crustal medium inhomogeneity beneath the Sichuan-Yunnan Block, the Sichuan-Qinghai Block, and the Mid-Sichuan Block may be related to intensive tectonic movement and material flow in the crust and upper mantle.

Prognostic significance of low expression of B-cell translocation gene 1 (BTG 1) in skin squamous cell carcinoma - Gongqi Li; Yinhong Yue; Wenxiu Li; Yumei Chen; Houzhen Fan; Jun Yuan; Zhongming Chen; Jun Liu (Journal of Biosciences, 2020)

Geographical origin differentiation of Chinese Angelica by specific metal element fingerprinting and risk assessment - Lei Sun; Xiao Ma; Hong-Yu Jin; Chang-jun Fan; Xiao-dong Li; Tian-Tian Zuo; Shuang-Cheng Ma; Sicen Wang (Environmental Science and Pollution Research, 2020)

The second messenger c-di-AMP mediates bacterial exopolysaccharide biosynthesis: a review - Zhi-Qiang Xiong; Yi-Zhou Fan; Xin Song; Xin-Xin Liu; Yong-Jun Xia; Lian-Zhong Ai (Molecular Biology Reports, 2020)

Using profitable chrysanthemums for phytoremediation of Cd- and Zn-contaminated soils in the suburb of Shanghai - Fan Luo; Xue-Feng Hu; Kokyo Oh; Li-Jun Yan; Xin-Zhe Lu; Wei-Jie Zhang; Tetsushi Yonekura; Shinichi Yonemochi; Yugo Isobe (Journal of Soils and Sediments, 2020)

Epidemiology of skeletal tuberculosis in Beijing, China: a 10-year retrospective analysis of data - Jun Fan; Jun An; Wei Shu; Fengmin Huo; Shanshan Li; Fen Wang; Shibing Qin; Yu Pang (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Carbon sequestration in aggregates from native and cultivated soils as affected by soil stoichiometry - Ruqin Fan; Jianjun Du; Aizhen Liang; Jun Lou; Jiangye Li (Biology and Fertility of Soils, 2020)

Isopimarane-type diterpenoids from Croton laevigatus - Man-Yu Li; Zheng-Zhi Han; Li-Fang Liu; Xiao-Zhen Wu; Wen-Jun Huang; Kai Wang; Fan Yang; Cheng-Shan Yuan (Natural Product Research, 2020)

Dietary Saccharina japonica is a natural and effective tool to fortify marine teleost black sea bream fillets with iodine: effects on growth, flesh quality, and serum thyroid hormones - Chuanqi Yu; Guoquan Liu; Jun Yu; Fan Lin; Xiaobo Wen (Journal of Applied Phycology, 2020)

Genetic mapping and utilization analysis of stripe rust resistance genes in a Tibetan wheat (Triticum aestivum L.) landrace Qubaichun - Jun Cao; Zhibin Xu; Xiaoli Fan; Qiang Zhou; Guangsi Ji; Fang Wang; Bo Feng; Tao Wang (Genetic Resources and Crop Evolution, 2020)

Spatial and seasonal variability of surface particulate inorganic carbon and relationship with particulate organic carbon in the Yellow-Bohai Sea - Xiujun Wang; Jun Yu; Hang Fan (Journal of Oceanography, 2020)

Psychroflexus maritimus sp. nov., isolated from coastal sediment - Yan-Lin Zhong; Rui Zhang; Xiao-Yu Zhang; Li-Xue Yu; Meng-Fan Zhao; Zong-Jun Du (Archives of Microbiology, 2020)

A new permeability predictive model based on NMR data for sandstone reservoirs - Hongjun Xu; Changxi Li; Yiren Fan; Falong Hu; Jun Yu; Jinyu Zhou; Changxue Wang; Chunmei Yang (Arabian Journal of Geosciences, 2020)

Ascorbic acid alleviation of manganese-induced toxicity in Vallisneria natans (Lour.) Hara - Pei Fan; Jun Yin; Guidi Zhong; Zhonghua Wu (Environmental Science and Pollution Research, 2020)

Extracellular ATP affects cell viability, respiratory O2 uptake, and intracellular ATP production of tobacco cell suspension culture in response to hydrogen peroxide-induced oxidative stress - Qin-zheng Hou; Yu-pei Wang; Bao-qiang Fan; Kun Sun; Jun-yu Liang; Han-qing Feng; Ling-yun Jia (Biologia, 2020)

The Oil Content Inversion of Tar Sands by Spectroscopy - Ruixue Fan; Lixin Xing; Jun Pan; Xuanlong Shan; Guangjie Luo; Changwei Li (Journal of the Indian Society of Remote Sensing, 2020)

Pseudorabies virus encephalitis in humans: a case series study - Siyuan Fan; Hongxun Yuan; Lei Liu; Hongfang Li; Shengnan Wang; Weili Zhao; Yihan Wu; Pei Wang; Yafang Hu; Jun Han; Yanli Lyu; Wuchao Zhang; et al. (Journal of NeuroVirology, 2020)

Late Jurassic I-type rhyolites from the Duobuza region, north-central Tibet: evidence for the occurrence of juvenile lower crust and crustal growth in the Southern Qiangtang Terrane - Yu-Chao Dong; Ming Wang; Jian-Jun Fan; Chao-Ming Xie; Yun-Peng Yu; Yu-Jie Hao (International Geology Review, 2020)

Mercury fluxes, budgets, and pools in forest ecosystems of China: A review - Jun Zhou; Buyun Du; Lihai Shang; Zhangwei Wang; Hongbiao Cui; Xingjun Fan; Jing Zhou (Critical Reviews in Environmental Science and Technology, 2020)

Comparative transcriptome analysis reveals a gene expression profile that contributes to rhizome swelling in Panax japonicus var. major - Jun Rong Tang; Ying Chun Lu; Zheng Jie Gao; Wan Ling Song; Kun Hua Wei; Yan Zhao; Qing Yan Tang; Xue Jiao Li; Jun Wen Chen; Guang Hui Zhang; Guang Qiang Long; Wei Fan; et al. (Plant Biosystems, 2020)

CHR721, interacting with OsRPA1a, is essential for both male and female reproductive development in rice - Yushun Zhang; Qiong Chen; Guanlin Zhu; Fang Zhang; Xiaohua Fang; Haibo Ren; Jun’e Jiang; Fang Yang; Dechun Zhang; Fan Chen (Plant Molecular Biology, 2020)

Comparative study on flash flood hazard assessment for Nam Ou River Basin, Lao PDR - Jun Du; Zhong-jie Fan; Jian Pu (Natural Hazards, 2020)

l-Glutamic acid induced the colonization of high-efficiency nitrogen-fixing strain Ac63 (Azotobacter chroococcum) in roots of Amaranthus tricolor - Yi-Fan Wang; Jun-Feng Wang; Zhi-Min Xu; Shao-Hua She; Jun-Qing Yang; Qu-Sheng Li (Plant and Soil, 2020)

Protective effect of apigenin on d-galactosamine/LPS-induced hepatocellular injury by increment of Nrf-2 nucleus translocation - Rui-Jun Zhou; Ying Zhao; Ke Fan; Mei-Lin Xie (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Evaluation of the relationship between DNA methylation status and heterosis in soybean with MethylRAD technique - Baixing Song; Yuanqian Wang; Songnan Yang; Xueying Li; Xiao Han; Sujie Fan; Abraham Lamboro; Dan Yao; Jing Qu; Zhuo Zhang; Yang Song; Jun Zhang (Euphytica, 2020)

Influence of canopy and topographic position on soil moisture response to rainfall in a hilly catchment of Three Gorges Reservoir Area, China - Muxing Liu; Qiuyue Wang; Li Guo; Jun Yi; Henry Lin; Qing Zhu; Bihang Fan; Hailin Zhang (Journal of Geographical Sciences, 2020)

Effects of dietary proline on growth, physiology, biochemistry and TOR pathway-related gene expression in juvenile spotted drum Nibea diacanthus - Hua Rong; Fan Lin; Yunlong Zhang; Jun Yu; Chuanqi Yu; Haoran Zhang; Jude Juventus Aweya; Xiaobo Wen (Fisheries Science, 2020)

A novel anammox reactor with a nitrogen gas circulation: performance, granule size, activity, and microbial community - Wenjing Chen; Shengdong Chen; Fan Hu; Wenru Liu; Dianhai Yang; Jun Wu (Environmental Science and Pollution Research, 2020)

Integrated fate assessment of aromatic amines in aerobic sewage treatment plants - Lin Jun Zhou; Zhi Yi Rong; Wen Gu; De Ling Fan; Ji Ning Liu; Li Li Shi; Yan Hua Xu; Zhi Ying Liu (Environmental Monitoring and Assessment, 2020)
The fate and exposure of chemicals in sewage treatment plants (STPs) are major considerations in risk assessment and environmental regulation. The biodegradability and removal of seven aromatic amines were systematically evaluated using a three-tiered integrated method: a standard ready biodegradability test, an aerobic sewage treatment simulation method, and model prediction. In tier 1, the seven aromatic amines were not readily biodegraded after 28 days. In adapted aerobic active sludge, 4-isopropyl aniline, 2,4-diaminotoluene, and 4-nitroaniline among them exhibited the degradation half-life time less than 20 h, the other four aromatic amines exhibited persistent with degradation half-life of > 60 h. In tier 2 of the aerobic sewage treatment simulation testing, 2,4-diaminotoluene, 4-nitroaniline, and 4-isopropylaniline demonstrated moderately to high overall removal. Hydraulic retention time (HRT) affects the removal with the optimum HRT was determined to be 12 h to 24. 2,6-Dimethyl aniline, 2-chloro-4-nitroaniline, 2,6-diethylaniline, and 3,4-dichloroaniline were not removed during the test, indicting these four aromatic amines will enter surface water and hence pose a potential risk to aquatic ecology. Considering the lack of an STP model in China for regulation purposes, in tier 3, we developed a Chinese STP (aerobic) (abbreviated as C-STP(O)) model that reflects a universal scenario for China to predict the fate. The predicted degradation, volatilization, and absorption showed a close relationship to the physicochemical properties of the chemicals, and had same tendency with tier 2 simulation test. The prediction showed that biodegradation rather than absorption or volatilization was the main removal process of aromatic amines in aerobic STP. With the combination of modified kinetics test with C-STP (O) model, the chemical fate can be more accurately predicted than using only the readily biodegradation result.

Controls on geomorphic characteristics of the Xiaohei River basin in the upper Lancang-Mekong, China - Zhen-kui Gu; Hui Fan; Jun-peng Lou; Kun Yang (Journal of Mountain Science, 2020)

Epidural Spinal Cord Stimulation Promotes Motor Functional Recovery by Enhancing Oligodendrocyte Survival and Differentiation and by Protecting Myelin after Spinal Cord Injury in Rats - Gang Li; Zhong-Kai Fan; Guang-Fei Gu; Zhi-Qiang Jia; Qiang-Qiang Zhang; Jun-Yu Dai; Shi-Sheng He (Neuroscience Bulletin, 2020)

RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice - Zhuanli Zhou; Jiayun Ni; Jingyao Li; Chuanbing Huo; Naijun Miao; Fan Yin; Qian Cheng; Dan Xu; Hongyan Xie; Panpan Chen; Peiqing Zheng; Yingying Zhang; et al. (Journal of Molecular Medicine, 2020)
Progressive tubulointerstitial fibrosis is the common final outcome for all kidney diseases evolving into chronic kidney disease (CKD), whereas molecular mechanisms driving fibrogenesis remain elusive. Retinoic acid-inducible gene-I (RIG-I), an intracellular pattern recognition receptor, is originally identified participating in immune response by recognizing virus RNA. Here, we revealed for the first time that RIG-I was induced in unilateral ureteral obstruction (UUO) and folic acid (FA) renal fibrosis models and moderate-degree renal fibrosis patients. Besides, we found RIG-I was mainly located in renal tubular epithelial cells and promoted the production and release of inflammatory cytokines, such as interleukin (IL)-1β and IL-6 through activation of NF-κB. Inflammatory cytokines released by tubular epithelial cells activated c-Myc-mediated TGF-β/Smad signaling in fibroblasts, which in turn aggravated interstitial fibrosis by promoting fibroblast activation and production of extracellular matrix components (ECM). Deficiency of RIG-I attenuated renal fibrosis by the regulation of inflammatory responses, c-Myc expression, and fibroblast activation. Besides, gene silencing of RIG-I reduced inflammatory cytokines in cultured tubular epithelial cells treated with Angiotensin II. Knockdown of c-Myc or c-Myc inhibitor blocked IL-1β-induced fibroblast activation. Collectively, our study demonstrates that RIG-I plays a significant role in the progress of renal fibrosis via regulating c-Myc-mediated fibroblast activation. Key messages • RIG-I was constantly elevated in kidneys from renal fibrotic mice. • RIG-I facilitated inflammatory cytokine production in tubular epithelial cells. • RIG-I aggravated renal fibrosis via c-Myc-mediated TGF-β/Smad activation.

Maternal urinary bisphenol A concentration and thyroid hormone levels of Chinese mothers and newborns by maternal body mass index - Xia Wang; Ning Tang; Shoji F. Nakayama; Pianpian Fan; Zhiwei Liu; Jun Zhang; Fengxiu Ouyang (Environmental Science and Pollution Research, 2020)

Correction to: The Effects of 50 nm Unmodified Nano-ZnO on Lipid Metabolism and Semen Quality in Male Mice - Tao Kong; Shu-Hui Zhang; Cai Zhang; Ji-Liang Zhang; Fan Yang; Guo-Yong Wang; Zi-Jun Yang; Dong-Ying Bai; Yun-Yun Shi; Tian-Qi Liu; Hai-Long Li (Biological Trace Element Research, 2020)

The Effects of 50 nm Unmodified Nano-ZnO on Lipid Metabolism and Semen Quality in Male Mice - Tao Kong; Shu-Hui Zhang; Cai Zhang; Ji-Liang Zhang; Fan Yang; Guo-Yong Wang; Zi-Jun Yang; Dong-Ying Bai; Yun-Yun Shi; Tian-Qi Liu; Hai-Long Li (Biological Trace Element Research, 2020)

Titanium dioxide nanoparticles via oral exposure leads to adverse disturbance of gut microecology and locomotor activity in adult mice - Shanshan Zhang; Xuejun Jiang; Shuqun Cheng; Jingchuan Fan; Xia Qin; Tianxiong Wang; Yujia Zhang; Jun Zhang; Yu Qiu; Jingfu Qiu; Zhen Zou; Chengzhi Chen (Archives of Toxicology, 2020)

Dating of detrital zircon grains and fossils from Late Palaeozoic sediments of the Baruo area, Tibet: constraints on the Late Palaeozoic evolution of the Lhasa terrane - Ming Wang; Xiao-wen Zeng; Chao-Ming Xie; Awang Danzeng; Cai Li; Jian-Jun Fan; Hang Li (International Geology Review, 2020)

Identification of odorant-binding proteins and functional analysis of antenna-specific AplaOBP1 in the emerald ash borer, Agrilus planipennis - Shan-Ning Wang; Shuang Shan; Guo-Yue Yu; He Wang; Khalid Hussain Dhiloo; Adel Khashaveh; Fan Zhang; Yong-Jun Zhang (Journal of Pest Science, 2020)

Hydro-geochemistry evolution in Ordovician limestone water induced by mountainous coal mining: A case study from North China - Chun-ming Hao; Yue Huang; Deng-jun Ma; Xing Fan (Journal of Mountain Science, 2020)

Maize NCP1 negatively regulates drought and ABA responses through interacting with and inhibiting the activity of transcription factor ABP9 - Na Zong; Hanqian Wang; Zaoxia Li; Li Ma; Li Xie; Junling Pang; Yunliu Fan; Jun Zhao (Plant Molecular Biology, 2020)

Erratum to: Exosome-derived galectin-9 may be a novel predictor of rejection and prognosis after liver transplantation - Ai-bin Zhang; Yi-fan Peng; Jun-jun Jia; Yu Nie; Shi-yu Zhang; Hai-yang Xie; Lin Zhou; Shu-sen Zheng (Journal of Zhejiang University-SCIENCE B, 2020)

Assessment of genetic integrity of Siberian wild rye (Elymus sibiricus L.) germplasm conserved ex situ and under accelerated aging using microsatellite markers - Fan Huang; Jun Li; Hongyan Li; Lei Liu; Wengui Shi; Zhiyong Li (Genetic Resources and Crop Evolution, 2020)

Uptake, depuration, bioaccumulation, and selective enrichment of dechlorane plus in common carp (Cyprinus carpio) - Dapeng Wang; Hongliang Jia; Wen-Jun Hong; Xiaohong Xue; Yeqing Sun; Yi-Fan Li; Weijun Guo (Environmental Science and Pollution Research, 2020)

The false smut pathogen Ustilaginoidea virens requires rice stamens for false smut ball formation - Jing Fan; Jie Liu; Zhi‐You Gong; Pei‐Zhou Xu; Xiao‐Hong Hu; Jin‐Long Wu; Guo‐Bang Li; Juan Yang; Yu‐Qiu Wang; Yu‐Feng Zhou; Shuang‐Cheng Li; Li Wang; et al. (Environmental Microbiology, 2020)
Summary Rice false smut has emerged as a serious grain disease in rice production worldwide. The disease is characterized by the transformation of individual rice florets into false smut balls, which is caused by the fungal pathogen Ustilaginoidea virens . To date, little is known about the host factors required for false smut ball formation by U . virens . In this study, we identified histological determinants for the formation of false smut balls by inoculating U . virens into rice floral mutants defective with respect to individual floral parts. The results showed that U . virens could form mature false smut balls in rice floral mutants with defective pistils, but failed to develop false smut balls in the superwoman mutant lacking stamens, identifying that U . virens requires rice stamens to complete its infection cycle. Comparative transcriptome analysis indicated a list of candidate host genes that may facilitate nutrient acquisition by U . virens from the rice stamens, such as SWEET11 , SWEET14 and SUT5 , and genes involved in the biosynthesis of trehalose and raffinose family sugars. These data pinpoint rice stamens as the key target organ of U . virens infection and provide a valuable starting point for dissecting the molecular mechanism of false smut ball formation.