Research characteristics and trends of power sector carbon emissions: a bibliometric analysis from various perspectives - Ke Liang; Wenjie Li; Junhui Wen; Weikun Ai; Jiabin Wang (Environmental Science and Pollution Research, 2023)

Streptomyces Spinosirectus sp. nov., Isolated From the Medicinal Plant Xanthium Sibiricum - Yin-Feng Wang; Si-Ren Hu; Li Fu; Yan Xiao; Xin-Ke Tang; Jian Gao (Current Microbiology, 2023)

A mitochondrial-targeted near-infrared fluorescent probe for visualizing the fluctuation of hypochlorite acid in idiopathic pulmonary fibrosis mice - Songjiao Li; Peipei Wang; Ying Liu; Ke Yang; Rongbin Zhong; Dan Cheng; Longwei He (Analytica Chimica Acta, 2023)

The self-powered electrochemical biosensing platform with multi-amplification strategy for ultrasensitive detection of microRNA-155 - Yong-ping Gao; Ke-jing Huang; Fu-ting Wang; Yang-yang Hou; Lu-di Zhao; Bo-ya Wang; Jing Xu; Honglei Shuai; Guoqiang Li (Analytica Chimica Acta, 2023)

The effect of chamber placement site on N2O emission under different fertilizer regimes from maize field - Cheng Liu; Yuan Liu; Wenhui Gao; Ke Gao; Jie Li; Baobao Sun; Xuhui Zhang; Shaopan Xia; Xiaoyu Liu; Lianqing Li; Genxing Pan (Agriculture, Ecosystems & Environment, 2023)

Hominibacterium faecale gen. nov., sp. nov., an anaerobic l-arginine-degrading bacterium isolated from human feces - Noori Borhanudin; Min Yang; Andrei V. Chaplin; Jiang Li; Qiong Wang; Li-rong Dai; Ke-jia Wu; Shi-chun Ma; Boris A. Efimov; Lei Cheng (Archives of Microbiology, 2023)

5′-Nucleotidase is dispensable for the growth of Salmonella Typhimurium but inhibits the bactericidal activity of macrophage extracellular traps - Man Qian; Ke Xu; Mengke Zhang; Junhui Niu; Tianxiang Zhao; Xiaoli Wang; Yanyan Jia; Jing Li; Zuhua Yu; Lei He; Yinju Li; Tingcai Wu; et al. (Archives of Microbiology, 2023)

Cultivation of fish ciliate parasites: Progress and prospects - Ming Li; Giana Bastos Gomes; Weishan Zhao; Guangran Hu; Ke Huang; Tomoyoshi Yoshinaga; Theodore G. Clark; Wenxiang Li; Hong Zou; Shangong Wu; Guitang Wang (Reviews in Aquaculture, 2023)
Ciliates are considered the most harmful parasites of fish, causing mass mortalities and thus substantial economic losses to the aquaculture and ornamental fish industries. To better elucidate their pathogenic mechanisms and facilitate the development of effective prevention and control strategies, it is essential to apply novel technologies to ensure the continuous and sufficient supply of parasite specimens. This review discusses the latest research progress in the artificial culture of six important parasitic ciliates affecting both freshwater and marine fish globally: Ichthyophthirius multifiliis , Cryptocaryon irritans , Chilodonella ( C. hexasticha , C. piscicola and C. uncinata ), Balantidium ctenopharyngodoni , Scuticociliatida gen. spp., and Tetrahymena spp. Methods for in vitro and in vivo culture as well as cryopreservation/preservation (depending on the specific species) of these organisms are described herein. Challenges and future applications of parasite culture are also discussed.

Cover Image - Ming Li; Giana Bastos Gomes; Weishan Zhao; Guangran Hu; Ke Huang; Tomoyoshi Yoshinaga; Theodore G. Clark; Wenxiang Li; Hong Zou; Shangong Wu; Guitang Wang (Reviews in Aquaculture, 2023)

Association between short- and long-term exposures to air pollutants and internalizing/externalizing behavior in children aged 4 to 7 years - Haiqin Qi; Anna Peng; Hong Mei; Yuanyuan Zhang; Ya Zhang; Paiziyeti Tuerxun; Wenli Dong; Chunan Li; Ke Xu; Ruixia Chang; Shaoping Yang; Jianduan Zhang (Environmental Science and Pollution Research, 2022)

Source-oriented ecological risk assessment of heavy metals in sediments of West Taihu Lake, China - Ning Li; Yan Li; Jiaxiang Wei; Ke Liu; Genmei Wang; Huanchao Zhang; Jiale Wen; Xinyu Cheng (Environmental Science and Pollution Research, 2022)

Numerical Analysis on Influences of Emergent Vegetation Patch on Runup Processes of Focused Wave Groups - Ke Qu; Yancheng Lie; Xu Wang; Xiaohan Li (Journal of Marine Science and Engineering, 2022)
During severe weather, the runup of the devasting surges and waves can cause extensive damages to the coastal facilities and results in significant loss of life. Therefore, it becomes necessary to find reliable measures to reduce the wave runup in coastal regions. As a natural barrier to the shorelines, coastal vegetation has great potential to attenuate wave runup and to prevent the coastal communities from extreme floodings and huge land loss. This study numerically discusses the influences of the emergent vegetation patch on the runup processes of extreme wave groups by applying a nonhydrostatic flow solver. Influences of the major factors, i.e., water depth, peak wave period, significant wave height, and density and length of the vegetation patch, are analyzed in detail. Research findings indicate that the presence of the emergent vegetation patch can substantially dissipate most of the incident wave energy and effectively reduce the maximum wave runup heights of extreme wave groups at the sloped beach. It is hoped that the research results of this study will be helpful to the design of coastal soft protection measures.

Changes of insular function in lifelong premature ejaculation patients before and after SSRI administration - Ming Gao; Bowen Geng; Shuming Zhang; Ke Xu; Pengyu Li; Duoli Chen; Xiao Zeng; Peng Liu; Yanzhu Wang (Psychopharmacology, 2022)

Scaling-up and proteomic analysis reveals photosynthetic and metabolic insights toward prolonged H2 photoproduction in Chlamydomonas hpm91 mutant lacking proton gradient regulation 5 (PGR5) - Peng Liu; De-Min Ye; Mei Chen; Jin Zhang; Xia-He Huang; Li-Li Shen; Ke-Ke Xia; Xiao-Jing Xu; Yong-Chao Xu; Ya-Long Guo; Ying-Chun Wang; Fang Huang (Photosynthesis Research, 2022)
Clean and sustainable H 2 production is crucial to a carbon–neutral world. H 2 generation by Chlamydomonas reinhardtii is an attractive approach for solar-H 2 from H 2 O. However, it is currently not large-scalable because of lacking desirable strains with both optimal H 2 productivity and sufficient knowledge of underlying molecular mechanism. We hereby carried out extensive and in-depth investigations of H 2 photoproduction of hpm91 mutant lacking PGR5 (Proton Gradient Regulation 5) toward its up-scaling and fundamental mechanism issues. We show that hpm91 is at least 100-fold scalable (up to 10 L) with continuous H 2 collection of 7287 ml H 2 /10L-HPBR in averagely 26 days under sulfur deprivation. Also, we show that hpm91 is robust and active during sustained H 2 photoproduction, most likely due to decreased intracellular ROS relative to wild type. Moreover, we obtained quantitative proteomic profiles of wild type and hpm91 at four representing time points of H 2 evolution, leading to 2229 and 1350 differentially expressed proteins, respectively. Compared to wild type, major proteome alterations of hpm91 include not only core subunits of photosystems and those related to anti-oxidative responses but also essential proteins in photosynthetic antenna, C/N metabolic balance, and sulfur assimilation toward both cysteine biosynthesis and sulfation of metabolites during sulfur-deprived H 2 production. These results reveal not only new insights of cellular and molecular basis of enhanced H 2 production in hpm91 but also provide additional candidate gene targets and modules for further genetic modifications and/or in artificial photosynthesis mimics toward basic and applied research aiming at advancing solar-H 2 technology.

Editorial Expression of Concern: Regulation of miR-19 to Breast Cancer Chemoresistance Through Targeting PTEN - Zhongxing Liang; Yuhua Li; Ke Huang; Nicholas Wagar; Hyunsuk Shim (Pharmaceutical Research, 2022)

Preoperative Acute Sleep Deprivation Causes Postoperative Pain Hypersensitivity and Abnormal Cerebral Function - Meimei Guo; Yuxiang Wu; Danhao Zheng; Lei Chen; Bingrui Xiong; Jinfeng Wu; Ke Li; Li Wang; Kangguang Lin; Zongze Zhang; Anne Manyande; Fuqiang Xu; et al. (Neuroscience Bulletin, 2022)

Research on time series InSAR monitoring method for multiple types of surface deformation in mining area - Ya-xing Li; Ke-ming Yang; Jian-hong Zhang; Zhi-xian Hou; Shuang Wang; Xin-ming Ding (Natural Hazards, 2022)

Environmental Factors Controlling Dissimilatory Nitrate Reduction to Ammonium in Paddy Soil - Zhijun Wei; Ke Jin; Chenglin Li; Min Wu; Jun Shan; Xiaoyuan Yan (Journal of Soil Science and Plant Nutrition, 2022)

Screening Major Properties of Biochar Affecting Acid Soil Amelioration Based on Pot Experiments and Random Forest Model - Xianlin Ke; Yan Wang; Minglong Liu; Zhuangzhi Yun; Rongjun Bian; Kun Cheng; Xiaoyu Liu; Jufeng Zheng; Xuhui Zhang; Lianqing Li; Genxing Pan (Journal of Soil Science and Plant Nutrition, 2022)

Nitrate Application Induces Adventitious Root Growth by Regulating Gene Expression Patterns in Apple Rootstocks - Muhammad Mobeen Tahir; Zhanling Lu; Chaojun Wang; Kamran Shah; Shaohuan Li; Xiaoyun Zhang; Jiangping Mao; Yu Liu; Abdullah Shalmani; Ke Li; Lu Bao; Dong Zhang (Journal of Plant Growth Regulation, 2022)

Energy substrate metabolism and oxidative stress in metabolic cardiomyopathy - Ze Chen; Zhao-Xia Jin; Jingjing Cai; Ruyan Li; Ke-Qiong Deng; Yan-Xiao Ji; Fang Lei; Huo-Ping Li; Zhibing Lu; Hongliang Li (Journal of Molecular Medicine, 2022)

Characteristic pollutants risk assessment of modified manganese residue utilization in sintered product - Chao-qiang Wang; Ke Liu; De-ming Huang; Qi-cong Huang; Pei-xin Wang; Xu-dong Mei; Shu-chun Li (Environmental Science and Pollution Research, 2022)

Effects of different silicate minerals on silicon activation by Ochrobactium sp. T-07-B - Ying Lv; Jia Li; Zhenxing Chen; Xingyu Liu; Bowei Chen; Mingjiang Zhang; Xuan Ke; Tian C. Zhang (Environmental Science and Pollution Research, 2022)

Overview of heavy metal pollution and health risk assessment of urban soils in Yangtze River Economic Belt, China - Shiqi Tang; Ke Yang; Fei Liu; Min Peng; Kuo Li; Zheng Yang; Xiujin Liu; Fei Guo; Honghong Ma (Environmental Geochemistry and Health, 2022)

Biological transfer of silver under silver nanoparticle exposure and nitrogen transfer via a collembolan-predatory mite food-chain and ecotoxicity of silver sulfide - Simin Li; Zhu Li; Xin Ke; Longhua Wu; Peter Christie (Soil Ecology Letters, 2022)

Downhill running induced DNA damage enhances mitochondrial membrane permeability by facilitating ER-mitochondria signaling - Junping Li; Binting Zhao; Shengju Chen; Zhen Wang; Kexin Shi; Binkai Lei; Chunxia Cao; Zhifei Ke; Ruiyuan Wang (Journal of Muscle Research and Cell Motility, 2022)

Recent advances in enterovirus A71 pathogenesis: a focus on fatal human enterovirus A71 infection - Jingjun Xing; Ke Wang; Geng Wang; Na Li; Yanru Zhang (Archives of Virology, 2022)

Serial structure multi-task learning method for predicting reservoir parameters - Bin-Sen Xu; Ning Li; Li-Zhi Xiao; Hong-Liang Wu; Feng-Zhou; Bing Wang; Ke-Wen Wang (Applied Geophysics, 2022)

CACNA1C-AS2 inhibits cell proliferation and suppresses cell migration and invasion via targeting FBXO45 and PI3K/AKT/mTOR pathways in glioma - Tong Cao; Yue Cui; Yingying Wang; Linhui Wu; Ke Yu; Kai Chen; Jun Xia; Yuyun Li; Zhiwei Peter Wang; Jia Ma (Apoptosis, 2022)

Abundant and diverse endophytic bacteria associated with medicinal plant Arctium lappa L. and their potential for host plant growth promoting - Jia-Qi Liu; Shu-Mei Chen; Chun-Mei Zhang; Ming-Jie Xu; Ke Xing; Cheng-Guo Li; Kui Li; Yu-Qin Zhang; Sheng Qin (Antonie van Leeuwenhoek, 2022)

Effects of elevated CO 2 and warming on the root‐associated microbiota in an agricultural ecosystem - Ke Gao; Zhenbo Mao; Enxi Meng; Jie Li; Xiaoyu Liu; Yingying Zhang; Long Zhang; Guangli Wang; Yuan Liu (Environmental Microbiology, 2022)
Plant root‐associated microbial communities profoundly affect plant nutrition and productivity. Although elevated atmospheric CO 2 and warming affect above‐ and belowground plant processes, it remains unclear how root‐associated microbial communities respond to elevated CO 2 and warming. In this study, an open‐air field experiment was conducted to assay the interactive effects of elevated CO 2 (500 ppm) and warming (+2°C) on the root‐associated microbiota and soil enzyme activities in a rice–wheat rotation ecosystem. The results revealed that elevated CO 2 significantly increased rhizosphere soil organic carbon (SOC) and total nitrogen contents. In addition, glucosidase, β‐xylosidase, and phosphatase activities significantly increased. The richness and Shannon diversity indices were significantly higher in rhizosphere soil than in root endosphere. Elevated CO 2 and warming significantly impacted the rhizosphere soil microbiota and altered their composition by changing the relative abundance of some specific groups. Soil pH, SOC, and available potassium content significantly altered the dominant bacterial phyla in the rhizosphere. SOC affected root endophytic bacterial phyla. Bacterial and fungal genera were significantly correlated with soil variables in the rhizosphere than in the root endosphere. These results indicate that microbial communities in the rhizosphere are more sensitive to elevated CO 2 and warming than those in the root endosphere.

The cAMP‐PKA signalling pathway regulates hyphal growth, conidiation, trap morphogenesis, stress tolerance, and autophagy in Arthrobotrys oligospora - Mei‐Chen Zhu; Na Zhao; Yan‐Kun Liu; Xue‐Mei Li; Zheng‐Yi Zhen; Ya‐Qing Zheng; Ke‐Qin Zhang; Jin‐Kui Yang (Environmental Microbiology, 2022)
The cyclic adenosine monophosphate‐protein kinase A (cAMP‐PKA) signalling pathway is evolutionarily conserved in eukaryotes and plays a crucial role in defending against external environmental challenges, which can modulate the cellular response to external stimuli. Arthrobotrys oligospora is a typical nematode‐trapping fungus that specializes in adhesive networks to kill nematodes. To elucidate the biological roles of the cAMP‐PKA signalling pathway, we characterized the orthologous adenylate cyclase AoAcy, a regulatory subunit (AoPkaR), and two catalytic subunits (AoPkaC1 and AoPkaC2) of PKA in A. oligospora by gene disruption, transcriptome, and metabolome analyses. Deletion of Aoacy significantly reduced the levels of cAMP and arthrobotrisins. Results revealed that Aoacy , AopkaR , and AopkaC1 were involved in hyphal growth, trap morphogenesis, sporulation, stress resistance, and autophagy. In addition, Aoacy and AopkaC1 were involved in the regulation of mitochondrial morphology, thereby affecting energy metabolism, whereas AopkaC2 affected sporulation, nuclei, and autophagy. Multi‐omics results showed that the cAMP‐PKA signalling pathway regulated multiple metabolic and cellular processes. Collectively, these data highlight the indispensable role of cAMP‐PKA signalling pathway in the growth, development, and pathogenicity of A. oligospora, and provide insights into the regulatory mechanisms of signalling pathways in sporulation, trap formation, and lifestyle transition.

Immunotherapies for the Effective Treatment of Primary Autoimmune Cerebellar Ataxia: a Case Series - Jiao Li; Bo Deng; Wenli Song; Keru Li; Jingwen Ai; Xiaoni Liu; Haocheng Zhang; Yi Zhang; Ke Lin; Guofu Shao; Chunfeng Liu; Wenhong Zhang; et al. (The Cerebellum, 2022)

Mulberry leaf extract improves non-specific immunity and antioxidant capacity of largemouth bass (Micropterus salmoides) fed a high-starch diet - Jing Tingsen; Luo Hui; Huang Junwa; Li Zhe; Li Yu; Jin Honghao; Zou Xinxi; Ke Zhenlin; Sun Wenbo; Hou Mengdan; Yang Huijun; Ye Hua (Frontiers in Marine Science, 2022)
A 70-day experiment was conducted to investigate the effects of mulberry leaf extract (MLE) on growth, proximate compositions, antioxidant and plasma biochemical parameters, and indices of non-specific immunity of largemouth bass ( Micropterus salmoides ) fed a high-starch diet. Two hundred eighty largemouth bass (initial body weight, 68.00 ± 0.19 g) were randomly fed seven diets: basal-starch diet (BSD; 8.88% starch), high-starch diet (HSD; 11.42% starch), and HSD diets supplemented with 0.05%, 0.10%, 0.20%, 0.50%, and 1.00% MLE (MLE1, MLE2, MLE3, MLE4, and MLE5, respectively). The results indicated that HSD and MLE did not significantly affect the growth performance of largemouth bass during the experimental period compared with that of the BSD, but the supplementation with more than 0.20% (MLE3, MLE4, and MLE5) MLE significantly decreased the hepatosomatic index (HSI) values, and 1.00% (MLE5) MLE significantly decreased the viscerosomatic index (VSI) values. The whole-body moisture of fish fed an HSD decreased significantly, while the whole-body lipid content increased significantly in the HSD group compared with the BSD group. Compared with HSD, MLE supplementation significantly decreased the moisture and lipid contents in the whole body. Supplementation with more than 0.20% MLE (MLE3, MLE4, and MLE5) significantly decreased the moisture content in the muscle. Supplementation with 1.00% MLE significantly decreased the content of hepatic and muscle glycogen. The malondialdehyde (MDA) content of the HSD group was significantly increased compared to that of the BSD group, whereas more than 0.10% (MLE2, MLE3, MLE4, and MLE5) MLE significantly decreased the MDA content. Additionally, the total antioxidant capacity (T-AOC), catalase (CAT), and glutathione peroxidase (GSH-Px) activities of MLE5 were significantly higher than those of the HSD group. The complement-3 (C3) content and globulin (GLB) in the plasma of the HSD group were significantly lower than those of the BSD group. Plasma C3 levels in the MLE3, MLE4, and MLE5 groups were significantly higher than those in the HSD group. In addition, glucose (GLU) levels in the MLE3, MLE4, and MLE5 groups were significantly lower than those in the HSD group. Supplementation with 0.50% (MLE4) MLE significantly increased the lysozyme (LYZ) content and decreased the activities of alanine transaminase (ALT) and aspartate transaminase (AST). Supplementation with 1.00% MLE significantly increased complement-4 (C4) and GLB contents and alkaline phosphatase (ALP) activity. Overall, these findings suggest that MLE could improve antioxidant capacity, immune function, and glycolipid metabolism, thereby alleviating the negative effects of a high-starch diet in M. salmoides .

The impact of low-carbon city pilot policy on green total-factor productivity in China’s cities - Ke-Liang Wang; Jin Li; Ru-Yu Xu; Su-Qin Pang; Zhuang Miao; Hua-Ping Sun (Environmental Science and Pollution Research, 2022)

The Application of Industrial Ecology Methods to Understand the Environmental and Economic Implications of the Forest Product Industries - Shiva Zargar; Bidhan Bhuson Roy; Qiuping Li; Jinlu Gan; Jinming Ke; Xiaoyu Liu; Qingshi Tu (Current Forestry Reports, 2022)

Experimental Investigation of the Dynamic Behavior of Submerged Floating Tunnels under Regular Wave Conditions - Fang Wang; Ke Li; Bo Huang; Liang Cheng; Hao Ding (Journal of Marine Science and Engineering, 2022)
Submerged floating tunnels (SFTs) are an innovative traffic structure for transportation in deep and long-distance ocean environments. SFTs have the risk of being subjected to wave action in the complex ocean environment. Therefore, in order to ensure the safety and stability of SFTs during their service, the dynamic behavior of an SFT subjected to the action of waves is experimentally investigated in this study. Based on the wave–current flume, a physical scale-model experiment of an SFT for studying the dynamic behavior of an SFT subjected to regular waves interactions is deeply and thoroughly explored. The results show that the wave outputs from the wave-making system are verified to be reliable. The influence of major load parameters on the dynamic behavior of the SFT are deeply and thoroughly explored. The effects of wave height and wave period on acceleration, wave pressure, anchor cable force and displacement in an SFT are discussed. This experimental study has theoretical and practical significant for SFT design and safety.

Ginsenoside Rb1 inhibits oxidative stress-induced ovarian granulosa cell injury through Akt-FoxO1 interaction - Ping Zhou; Feng Deng; Zi Yang; Canhui Cao; Hongcui Zhao; Fenting Liu; Ke Zhong; Lin Fu; Tianliu Peng; Di Sun; Hui Liu; Rong Li; et al. (Science China Life Sciences, 2022)

Bone Marrow Mesenchymal Stem Cell Exosome Attenuates Inflammasome-Related Pyroptosis via Delivering circ_003564 to Improve the Recovery of Spinal Cord Injury - Yanyin Zhao; Yu Chen; Zhiwei Wang; Changli Xu; Suchi Qiao; Tianze Liu; Ke Qi; Dake Tong; Cheng Li (Molecular Neurobiology, 2022)

CAF-derived midkine promotes EMT and cisplatin resistance by upregulating lncRNA ST7-AS1 in gastric cancer - Ke-Da Yang; Ying Wang; Fan Zhang; Qing-Ling Li; Bai-Hua Luo; De-Yun Feng; Zhi-Jun Zeng (Molecular and Cellular Biochemistry, 2022)

Adsorption of di (2-ethylhexyl) phthalate (DEHP) to microplastics in seawater: a comparison between pristine and aged particles - Ke Pan; Ciara Chun Chen; Lin Lin; Huo Xu; Fengyuan Chen; Yanping Li; Xiaoshan Zhu; Jie Ma; Wenlu Lan (Bulletin of Environmental Contamination and Toxicology, 2022)

Centrifuge and numerical modeling of the impact of sediment consolidation induced by capping on contaminant transportation - Jian Zheng; Yu-Chao Li; Han Ke; Yun-Min Chen (Bulletin of Engineering Geology and the Environment, 2022)

Study on aptamer based high throughput approach identifies natural ingredients against RGNNV - Hongling Wei; Mingzhu Liu; Ke Ke; Shuangyan Xiao; Lin Huang; Qiongyu He; Changping Mo; Hai Pang; Guozhu Xiao; Pengfei Li; Qing Yu (Journal of Fish Diseases, 2022)
Nervous necrosis virus (NNV) is one of the most destructive pathogens in marine fish aquaculture and is capable of infecting more than 50 fish species worldwide, which resulted in great economic losses. Effective drugs for managing NNV infection are urgently required. Medicinal plants have been known for thousands of years and benefit of medicinal plants against pathogens in aquaculture have emerged. Nowadays, the most commonly used method for detecting virus infection and assessing antiviral drugs efficacy is reverse transcription‐quantitative real‐time PCR. However, the application is limited on account of high reagent costs, complex time‐consuming operations and long detection time. Aptamers have been widely applied in application of pathogens or diseases diagnosis and treatments because of high specificity, strong affinity, good stability, easy synthesized and low costs. This study aimed to establish an aptamer (GBN34)‐based high‐throughput screening (GBN34‐AHTS) model for efficient selection and evaluation of natural ingredients against NNV infection. GBN34‐AHTS is an expeditious rapid method for selecting natural ingredients against NNV, which is characterized with high‐speed, dram, sensitive and accurate. AHTS strategy could reduce work intensity and experimental costs and shorten the whole screening cycle of effective ingredients. AHTS should be suitable for rapid selection of effective ingredients against other viruses, which is important for improving the prevention and controlling of aquatic diseases.

Exploratory analysis of the association between organophosphate ester mixtures with high blood pressure of children and adolescents aged 8–17 years: cross-sectional findings from the National Health and Nutrition Examination Survey - Xianwei Guo; Yujie Ke; Birong Wu; Qiuxia Song; Chenyu Sun; Yaru Li; Hao Wang; Wanying Su; Qiwei Liang; Scott Lowe; Rachel Bentley; Evelyn J. Song; et al. (Environmental Science and Pollution Research, 2022)

Photosynthetic regulation in response to strontium stress in moss Racomitrium japonicum L - Hui Ren; Renhua Huang; Ying Li; Wanting Li; Liuliu Zheng; Yanbao Lei; Ke Chen (Environmental Science and Pollution Research, 2022)

Design and Experimental Study of a Transverse Metering Device for Precut Sugarcane Setts - Fanglan Ma; Ke Li; Xiaohu Luo; Shangping Li; Xiao Teng (Sugar Tech, 2022)

Tumor necrosis factor-α coordinates with transforming growth factor-β1 to induce epithelial-mesenchymal transition and migration via the NF-κB/NOX4 pathway in bronchial epithelial cells - Ke Li; Rong Zhou; Mingze Ma; Chaomei Jin; Linlin Jiao; Siyu Zhang; Mei Tian; Fang Zhou (Molecular Biology Reports, 2022)

Phosphorylation of Truncated Tau Promotes Abnormal Native Tau Pathology and Neurodegeneration - Longfei Li; Yanli Jiang; Gang Wu; Yacoubou Abdoul Razak Mahaman; Dan Ke; Qun Wang; Bin Zhang; Jian-Zhi Wang; Hong-Lian Li; Rong Liu; Xiaochuan Wang (Molecular Neurobiology, 2022)

The Key Role of Magnetic Resonance Imaging in the Detection of Neurodegenerative Diseases-Associated Biomarkers: A Review - Ke-Ru Li; An-Guo Wu; Yong Tang; Xiao-Peng He; Chong-Lin Yu; Jian-Ming Wu; Guang-Qiang Hu; Lu Yu (Molecular Neurobiology, 2022)

iTRAQ-based proteomics analysis of diethylstilbestrol induced dysfunction of testicular gubernaculum development in mouse - Hongyan Ping; Degang Wang; Maxian Fu; Kaihong Chen; Jiuhong Zhang; Ke Li; Xuewu Jiang; Shouxing Duan; Xuan Zhang (Molecular & Cellular Toxicology, 2022)

mTOR is involved in LRP5-induced osteogenic differentiation of normal and aged periodontal ligament stem cells in vitro - Ke Yu; Chengze Wang; Yongzheng Li; Zhiwei Jiang; Guoli Yang; Ying Wang (Journal of Molecular Histology, 2022)

A Novel Fully Automated MRI-Based Deep-Learning Method for Segmentation of Nasopharyngeal Carcinoma Lymph Nodes - Yishu Deng; Dan Hou; Bin Li; Xing Lv; Liangru Ke; Mengyun Qiang; Taihe Li; Bingzhong Jing; Chaofeng Li (Journal of Medical and Biological Engineering, 2022)

Spatial and interdecadal differences in climatic suitability for winter wheat in China from 1985 to 2014 - Ke-xin Li; Fei Zheng (International Journal of Biometeorology, 2022)

Dietary supplementation of two indigenous Bacillus spp on the intestinal morphology, intestinal immune barrier and intestinal microbial diversity of Rhynchocypris lagowskii - Xin-yu Lei; Dong-ming Zhang; Qiu-ju Wang; Gui-qin Wang; Yue-hong Li; Yu-rou Zhang; Men-nan Yu; Qi Yao; Yu-ke Chen; Zhi-xin Guo (Fish Physiology and Biochemistry, 2022)

Causal association between metro transits and air quality: China’s evidence - Ke Li; Weihong Yuan; Jianglong Li (Environmental Science and Pollution Research, 2022)

Dynamic pollution emission prediction method of a combined heat and power system based on the hybrid CNN-LSTM model and attention mechanism - Anping Wan; Jie Yang; Ting Chen; Yang Jinxing; Ke Li; Zhou Qinglong (Environmental Science and Pollution Research, 2022)

Influence of algal organic matter on metal accumulation in adjacent sediments of aquaculture from a tropical coast region - Shiquan Chen; Ke Pan; Wenqin Li; Dandan Duan (Environmental Science and Pollution Research, 2022)

Study on the changes of Structural Covariance Network in post-traumatic stress disorder - Tongtong Xu; Feng Chen; Li Zhang; Yingliang Dai; Jun Ke; Rongfeng Qi; Guangming Lu; Yuan Zhong (Brain Imaging and Behavior, 2022)

Classification of Parkinson’s disease using a region-of-interest- and resting-state functional magnetic resonance imaging-based radiomics approach - Dafa Shi; Xiang Yao; Yanfei Li; Haoran Zhang; Guangsong Wang; Siyuan Wang; Ke Ren (Brain Imaging and Behavior, 2022)

Changes in plant anthocyanin levels in response to abiotic stresses: a meta-analysis - Wenjie Yan; Juanjuan Li; Xinyue Lin; Lina Wang; Xiaoxiao Yang; Xiangyu Xia; Yuxin Zhang; Shaoyu Yang; Hongbing Li; Xiping Deng; Qingbo Ke (Plant Biotechnology Reports, 2022)

Mechanism of progressive failure of a slope with a steep joint under the action of freezing and thawing: model test - Cong Li; Rong-tang Zhang; Jie-bing Zhu; Bo Lu; Xiao-ke Shen; Xiao-wei Wang; Jie-sheng Liu; Liang-liang Wu; Xin-zhou Zhang (Journal of Mountain Science, 2022)

CircRNA CORO1C Regulates miR-654-3p/USP7 Axis to Mediate Laryngeal Squamous Cell Carcinoma Progression - Jianbin Zhang; He Li; Jiangping Li; Saixiong Ke (Biochemical Genetics, 2022)

Transcriptome analysis and co‐expression network reveal the mechanism linking mitochondrial function to immune regulation in red crucian carp ( Carassius auratus red var) after Aeromonas hydrophila challenge - Ning‐Xia Xiong; Xu‐Ying Kuang; Zi‐Xuan Fang; Jie Ou; Shi‐Yun Li; Jia‐Hui Zhao; Jin‐Fang Huang; Ke‐Xin Li; Rou Wang; Lan‐Fen Fan; Sheng‐Wei Luo; Shao‐Jun Liu (Journal of Fish Diseases, 2022)
Aeromonas hydrophila is a common pathogen of freshwater fish. In this study, A. hydrophila infection was shown to cause tissue damage, trigger physiological changes as well as alter the expression profiles of immune‐ and metabolic‐related genes in immune tissues of red crucian carp (RCC). Transcriptome analysis revealed that acute A. hydrophila infection exerted a profound effect on mitochondrial oxidative phosphorylation linking metabolic regulation to immune response. In addition, we further identified cellular senescence, apoptosis, necrosis and mitogen‐activated protein kinase signal pathways as crucial signal pathways in the kidney of RCC subjected to A. hydrophila infection. These findings may have important implications for understanding modulation of immunometabolic response to bacterial infection.

Functional analysis, diversity, and distribution of carbendazim hydrolases MheI and CbmA , responsible for the initial step in carbendazim degradation - Mingliang Zhang; Xuekun Bai; Qian Li; Lu Zhang; Qian Zhu; Siyuan Gao; Zhijian Ke; Mingli Jiang; Junqiang Hu; Jiguo Qiu; Qing Hong (Environmental Microbiology, 2022)
Strains Rhodococcus qingshengii djl‐6 and Rhodococcus jialingiae djl‐6‐2 both harbour the typical carbendazim degradation pathway with the hydrolysis of carbendazim to 2‐aminobenzimidazole (2‐AB) as the initial step. However, the enzymes involved in this process are still unknown. In this study, the previous reported carbendazim hydrolase MheI was found in strain djl‐6, but not in strain djl‐6‐2, then another carbendazim hydrolase CbmA was obtained by a four‐step purification strategy from strain djl‐6‐2. CbmA was classified as a member of the amidase signature superfamily with conserved catalytic site residues Ser157, Ser181, and Lys82, while MheI was classified as a member of the Abhydrolase superfamily with conserved catalytic site residues Ser77 and His224. The catalytic efficiency ( k cat / K m ) of MheI (24.0–27.9 μM −1 min −1 ) was 200 times more than that of CbmA (0.032–0.21 μM −1 min −1 ). The mheI gene (plasmid encoded) was highly conserved (>99% identity) in the strains from different bacterial genera and its plasmid encoded flanked by mobile genetic elements. The cmbA gene was highly conserved only in strains of the genus Rhodococcus and it was chromosomally encoded. Overall, the function, diversity, and distribution of carbendazim hydrolases MheI and CbmA will provide insights into the microbial degradation of carbendazim.

Adsorption properties and mechanism research of phosphorus with different molecular structures from aqueous solutions by La-modified biochar - Ming-yao Yuan; Shang-kai Qiu; Meng-meng Li; Yuan Li; Ji-Xiu Wang; Yuan Luo; Ke-qiang Zhang; Feng Wang (Environmental Science and Pollution Research, 2022)

Development of 45 SNP markers in Triplophysa hsutschouensis based on RAD sequencing - Ya Liu; Jiansheng Lai; Zhongmeng Zhao; Hongyu Ke; Han Zhao; Yeyu Chen; Xiaoyun Wu; Qiang Li (Conservation Genetics Resources, 2022)

Niacin mitigates rumen epithelial damage in vivo by inhibiting rumen epithelial cell apoptosis on a high concentrate diet - Zhen Gao; Yanjiao Li; Chao Xu; Dan Luo; Qinghua Qiu; Ke Pan; Xiaowen Xiong; Mingren Qu; Kehui Ouyang (Veterinary Research Communications, 2022)

Stat5−/− CD4+ T cells elicit anti-melanoma effect by CD4+ T cell remolding and Notch1 activation - Ke Jin; Tong Li; Zhiyong Miao; Jingjing Ran; Luyu Chen; Dachao Mou; Chuang Wang; Shasha Wu; Hanshuo Yang; Xin-Yuan Fu (Science China Life Sciences, 2022)

mTOR-FABP4 signal is activated in brain arteriovenous malformations in humans - Debin Yan; Qiang Hao; Yu Chen; Zhipeng Li; Haibin Zhang; Kexin Yuan; Runting Li; Ruinan Li; Yahui Zhao; Ke Wang; Hao Peng; Dong Zhang; et al. (Journal of Molecular Medicine, 2022)

QTL analysis for 27 quality traits measured through the color of end-use products in common wheat (Triticum aestivum L.) - Xiaoling Jiang; Zhongxing Wang; Jishun Zhao; Qingyun Guan; Zehua Ke; Xiaojun Li; Ziyang Zhang; Jichun Tian; Hongmin Li; Jiansheng Chen (Euphytica, 2022)

Does the promotion pressure on local officials matter for regional carbon emissions? Evidence based on provincial-level leaders in China - Xiude Chen; Yanting Ke; Huiyang Li; Yazhi Song; Yulian Peng (Environmental Geochemistry and Health, 2022)

A single-cell survey unveils cellular heterogeneity and sensitive responses in mouse cortices induced by oral exposure to triphenyl phosphate - Di Ji; Yuejin Yu; Qicheng Zhu; Xianjie Li; Xiali Zhong; Zhuyi Zhang; Weijian Ke; Congying Niu; Can Wang; Jingwei Wu; Da Chen; Maoyong Song; et al. (Archives of Toxicology, 2022)

Petrophysical characteristics of shale oil reservoirs in the Yanchang Formation, Ordos Basin - Si-Xin Zhu; Li-Ming An; Yong-Kang Li; Xiao-Dong Zhang; Fan-Ke Meng (Applied Geophysics, 2022)

Self-adaptive inversion method of electromagnetic-propagation resistivity logging while drilling data - Wei Xu; Hang Huang; Xin Li; Shi-Zhen Ke (Applied Geophysics, 2022)

Hyphomonas sediminis sp. nov., isolated from marine sediment - Lu Wang; Wei He; Zeng-Yu Gao; Dao-Feng Zhang; Jian-Ke Huang; Chuang Liu; Wen-Jun Li; Ai Hua Zhang (Antonie van Leeuwenhoek, 2022)

A lens-shaped, cold-core anticyclonic surface eddy in the northern South China Sea - Yongfeng Qi; Huabin Mao; Yan Du; Xianpeng Li; Zhou Yang; Ke Xu; Ying Yang; Wanxuan Zhong; Fuchang Zhong; Linghui Yu; Huanlin Xing (Frontiers in Marine Science, 2022)
Typically, compared with the normal ocean, an anticyclonic eddy has higher sea surface temperature (SST), greater surface mixed-layer depth (MLD), and a bowl-shaped structure under the action of geostrophy. This study is the first to report an abnormal anticyclonic eddy characterized by a lens-shaped structure, cold core, and shallower MLD, which were observed in situ in the northern South China Sea (SCS) in September 2021. The SST at core of the anticyclonic eddy was 0.4°C lower than that in its peripheral region. The MLD at the center of the eddy was about half of that outside the eddy. Below the surface mixed layer, a lens-shaped structure containing relatively well-mixed water was observed between the two high-gradient layers. Within this lens-shaped structure, the isothermal layers were stretched, but accompanied by water mixing that was about one third of that at the upper and lower bounds of the structure. This eddy originated from a Kuroshio Current intrusion in late October 2020 and died in November 2021, such that its lifespan exceeded 1 year. The shedding of the Kuroshio Loop into the SCS under strong air–sea interactions under continuous sea surface cooling in winter was considered a key mechanism for the generation of the cold core of the eddy. The lens-shaped structure formed below the surface mixed layer and was maintained through geostrophic balance by the subsurface maximum speeds of the Kuroshio Current intrusion (50–100 m), thereby forming a shallower MLD in the eddy center. The subsurface speed maximum within the eddy was also observed by a shipborne acoustic Doppler current profiler at 10 months after its formation, confirming the hypothesized mechanism. This type of abnormal anticyclonic may be a common phenomenon in the northern SCS and has potential implications for the local biogeochemistry, local heat budget, and regional oceanic models.

Time Trends and Forecasts of Atmospheric Heavy Metals in Lanzhou, China, 2015–2019 - Meixia Du; Xiaochun Yin; Yongjun Li; Ting Ke; Hai Zhu; Jianjun Wu; Guisen Zheng (Water, Air, & Soil Pollution, 2022)

Super Stability of Cu-Mn/Y Bimetallic Catalyst for Ozone-assisted Catalytic Oxidation of Toluene - Ke Xia; Jin-Hua Huang; Li-Ping Ye (Water, Air, & Soil Pollution, 2022)

Intrauterine hyperglycemia impairs endometrial receptivity via up-regulating SGK1 in diabetes - Haiyan Xu; Jingyi Li; Luyang Jin; Dan Zhang; Bin Chen; Xinmei Liu; Xianhua Lin; Yiting Huang; Zhanghong Ke; Juan Liu; Lin Gao; Jianzhong Sheng; et al. (Science China Life Sciences, 2022)

VGLUT3 neurons in median raphe control the efficacy of spatial memory retrieval via ETV4 regulation of VGLUT3 transcription - Aodi He; Chen Zhang; Xiao Ke; Yao Yi; Quntao Yu; Tongmei Zhang; Hongyan Yu; Huiyun Du; Hao Li; Qing Tian; Ling-Qiang Zhu; Youming Lu (Science China Life Sciences, 2022)

A strategy for establishing an efficient somatic embryo regeneration system in Castanea mollissima Blume - Xiao-wei Li; Zhi-lin Sun; Yue-rong Gao; Jing-yi Ge; Yu-zhen Tian; Bing Liu; Shi-kan Sun; Ke-feng Fang; Ling Qin; Qing-qin Cao (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

The traditional uses, secondary metabolites, and pharmacology of Eleutherococcus species - Yue-Hui Huang; Jin-Tao Li; Ke Zan; Jun Wang; Qiang Fu (Phytochemistry Reviews, 2022)

Heroin Addiction Induces Axonal Transport Dysfunction in the Brain Detected by In Vivo MRI - Yueyuan Luo; Chengde Liao; Long Chen; Yongjin Zhang; Shasha Bao; Ailin Deng; Tengfei Ke; Qinqing Li; Jun Yang (Neurotoxicity Research, 2022)

miR-517b-3p promotes the progression of portal vein tumor thrombus via activating Wnt/β-catenin signaling pathway in hepatocellular carcinoma - Rui-Sheng Ke; Kun-Zhai Huang; De-sheng Bao; Jing-Rui Yang; Hua-xiang Wang; Li-Zhi Lv; Yi Jiang; Zhao-Hui Liu; Fu-Xing Zhang (Molecular Biology Reports, 2022)

Synthesis and antitumor activity evaluation in vitro of 4-aminoquinazoline derivatives containing 1,3,4-thiadiazole - Xiaojie Si; Honglin Dai; Chao Gao; Hao Wang; Lingling Chi; Zhangjie Wang; Limin Liu; Luye Zhang; Erdong Li; Jiaxin Zheng; Yaoyao Wang; Yu Ke; et al. (Medicinal Chemistry Research, 2022)

Disruption of mstn Gene by CRISPR/Cas9 in Large Yellow Croaker (Larimichthys crocea) - Mengzhen Yan; Bijun Li; Jiaying Wang; Yulin Bai; Qiaozhen Ke; Tao Zhou; Peng Xu (Marine Biotechnology, 2022)

Chitosan and D-fructose 1,6-bisphosphate differ in their effects on soil acidity and aluminum activation - Jackson Nkoh Nkoh; Xian He; Hai-long Lu; Ke-wei Li; Ren-yong Shi; Jiu-yu Li; Ren-kou Xu (Journal of Soils and Sediments, 2022)

Comparative Analysis of Endogenous Hormones and Metabolite Profiles in Early-Spring Flowering Plants and Unflowered Plants Revealing the Strategy of Blossom - Xue Yan; Jia Liu; Ke-Xin Wu; Nan Yang; Li-Ben Pan; Ying Song; Yang Liu; Zhong-Hua Tang (Journal of Plant Growth Regulation, 2022)

Experimental simulation of water and air migration under the presence of fissures and paleosols in unsaturated loess slopes - Peng Liu; Xianmin Ke; Wei Wang; Yitian Liu; Xiujuan Li (Hydrogeology Journal, 2022)

Integrated analysis of the miRNA and mRNA expression profiles in Leiocassis longirostris at gonadal maturation - Han Zhao; Lu Zhang; Qiang Li; Zhongmeng Zhao; Yuanliang Duan; Zhipeng Huang; Hongyu Ke; Chao Liu; Huadong Li; Lu Liu; Jun Du; Zhen Wei; et al. (Functional & Integrative Genomics, 2022)

A review of spatiotemporal patterns of neonicotinoid insecticides in water, sediment, and soil across China - Zhikun Liu; Leiming Zhang; Zulin Zhang; Lihui An; Rupert Hough; Peng Hu; Yi-Fan Li; Fuxiang Zhang; Shuang Wang; Yunqing Zhao; Yuxin Ke; Song Cui (Environmental Science and Pollution Research, 2022)

Can collaborative innovation constrain ecological footprint? Empirical evidence from Guangdong-Hong Kong-Macao Greater Bay Area, China - Xiaojun You; Qixiang Li; Kyle M. Monahan; Fei Fan; Haiqian Ke; Na Hong (Environmental Science and Pollution Research, 2022)

Runoff projections of the Qinling Mountains and their impact on water demand of Guanzhong region in Northwest China - Zhao-peng Zhang; Ke-qin Duan; Huan-cai Liu; Ya-li Meng; Rong Chen; Da-wei Li; Shuang-shuang Li (Journal of Mountain Science, 2022)

Reliable reference genes for qPCR normalization in females of the mirid predator, Cyrtorhinus lividipennis (Hemiptera: Miridae) - Kui Hu; Ke Chen; Baobao Fu; Jianqi Liu; Yan Li; Qinjian Pan; Fang Liu (Biologia, 2022)

Lelliottia steviae sp. nov. isolated from Stevia rebaudiana Bertoni - Jing Lin; Ke Huang; Jing-Yu Huang; Yuan-Ru Xiong; Meng-Meng Wei; Na Xiao; Jia Gao; Xuan-Kai Ding; Zi-Yang Ma; Jun-Hao Sang; Ling-Xian Kong; Zhi-Yun Hong; et al. (Archives of Microbiology, 2022)

High glucose-induced ROS-accumulation in embryo-larval stages of zebrafish leads to mitochondria-mediated apoptosis - Yaoqi Li; Qianqian Chen; Yinai Liu; Liuliu Bi; Libo Jin; Ke Xu; Renyi Peng (Apoptosis, 2022)

Effects of daily nitrogen and phosphorus input on planktonic community metabolism in a semi-enclosed bay by mesocosm experiment - Chenhui Xiang; Yao Li; Zhixin Ke; Gang Li; Yadong Huang; Xinying Su; Liangmin Huang; Xinyu Song (Acta Oceanologica Sinica, 2022)

Meta-analysis of the effect of melatonin application on abiotic stress tolerance in plants - Xiaoxiao Yang; Jianhong Ren; Juanjuan Li; Xinyue Lin; Xiangyu Xia; Wenjie Yan; Yuxin Zhang; Xiping Deng; Qingbo Ke (Plant Biotechnology Reports, 2022)

Post-transcriptional control of bacterial nitrogen metabolism by regulatory noncoding RNAs - Yueyue Han; Chao Li; Yongliang Yan; Min Lin; Xiubin Ke; Yunhua Zhang; Yuhua Zhan (World Journal of Microbiology and Biotechnology, 2022)
Nitrogen metabolism is the most basic process of material and energy metabolism in living organisms, and processes involving the uptake and use of different nitrogen sources are usually tightly regulated at the transcriptional and post-transcriptional levels. Bacterial regulatory noncoding RNAs are novel post-transcriptional regulators that repress or activate the expression of target genes through complementarily pairing with target mRNAs; therefore, these noncoding RNAs play an important regulatory role in many physiological processes, such as bacterial substance metabolism and stress response. In recent years, a study found that noncoding RNAs play a vital role in the post-transcriptional regulation of nitrogen metabolism, which is currently a hot topic in the study of bacterial nitrogen metabolism regulation. In this review, we present an overview of recent advances that increase our understanding on the regulatory roles of bacterial noncoding RNAs and describe in detail how noncoding RNAs regulate biological nitrogen fixation and nitrogen metabolic engineering. Furthermore, our goal is to lay a theoretical foundation for better understanding the molecular mechanisms in bacteria that are involved in environmental adaptations and metabolically-engineered genetic modifications.

Diminished miR-374c-5p negatively regulates IL (interleukin)-6 in unexplained recurrent spontaneous abortion - Lin Zhao; Li Han; Guozhen Hei; Ran Wei; Zhen Zhang; Xiaoxiao Zhu; Qiang Guo; Chu Chu; Xiaoxiao Fu; Ke Xu; Xia Li (Journal of Molecular Medicine, 2022)

Construction and comprehensive analysis of a lncRNA–mRNA interactive network to reveal a potential lncRNA for hepatic encephalopathy development - Chihao Zhang; Wei Ni; Yiming Zhu; Jiayun Lin; Hongjie Li; Zhifeng Zhao; Ke Wang; Haizhong Huo; Meng Luo (Human Cell, 2022)

Correction to: Short‑term effects of gaseous air pollutants on outpatient visits for respiratory diseases: a case‑crossover study in Baotou, China - Hao‑Yu Gao; Xiao‑Ling Liu; Ya‑Ke Lu; Yu‑Hong Liu; Li‑Kun Hu; Yan‑Ling Li; Xiao‑Dong Feng; Yu‑Xiang Yan (Environmental Science and Pollution Research, 2022)

Short-term effects of gaseous air pollutants on outpatient visits for respiratory diseases: a case-crossover study in Baotou, China - Hao-Yu Gao; Xiao-Ling Liu; Ya-Ke Lu; Yu-Hong Liu; Li-Kun Hu; Yan-Ling Li; Xiao-Dong Feng; Yu-Xiang Yan (Environmental Science and Pollution Research, 2022)

Assessing economic sustainability and ecological efficiency with genuine progress indicator: a case study of the Yangtze River Delta from 2000 to 2018 - Yongjun Li; Jing Qiao; Lei Xie; Lingyan Huang; Yue Su; Mengmeng Zhou; Ke Wang; Jing Zhang; Shan He; Lu Huang (Environmental Science and Pollution Research, 2022)

Testing the transfer functions for the Geonor T-200B and Chinese standard precipitation gauge in the central Qinghai—Tibet Plateau - Le-le Zhang; Li-ming Gao; Ji Chen; Lin Zhao; Ke-long Chen; Jing-yi Zhao; Guo-jun Liu; Ting-xi Song; Yan-kun Li (Journal of Mountain Science, 2022)

Nile tilapia TRIM39 recruits I3K413 and I3KL45 as adaptors and is involved in the NF‐κB pathway - Feng‐ying Gao; Xin Zhou; Mai‐xin Lu; Miao Wang; Zhi‐gang Liu; Jiang‐meng Cao; Xiao‐li Ke; Meng‐meng Yi (Journal of Fish Biology, 2022)
Tripartite motif (TRIM) proteins play a regulatory function in cancer, cell apoptosis and innate immunity. To understand the role of TRIM39 in Nile tilapia ( Oreochromis niloticus ), TRIM39 cDNA was isolated. The total length of TRIM39 cDNA was 5025 bp. The deduced OnTRIM39 protein contains 549 amino acids and has conserved domains of the TRIM family, which are the RING, B‐box, coiled‐coil and PRY‐SPRY domains. OnTRIM39 mRNA was widely expressed in various tissues. After challenge with Streptococcus agalactiae and stimulation with polyinosinic polycytidylic acid [poly (I:C)] and lipopolysaccharides (LPS), the amount of OnTRIM39 transcript was changed in various tested tissues. OnTRIM39 overexpression increased NF‐κB activity. OnTRIM39 was present in the cytoplasm. Mass spectrometry of proteins pulled down with recombinant OnTRIM39 showed that 250 proteins potentially interact with OnTRIM39. The authors selected I3K4I3 from the 250 candidate proteins to verify its interaction with TRIM39. They also selected I3KL45, a member of the same 14‐3‐3 protein family, to verify its interaction with TRIM39. The results of pull‐down assays showed that OnTRIM39 interacted with both I3K413 and I3KL45. These results contribute to further study of the innate immune mechanism of tilapia.

Design and Reconfiguration of Multicomponent Hydrodynamic Manipulation Devices with Arbitrary Complex Structures - Haixiang Pang; Yunxiang You; Tingqiu Li; Ke Chen; Li Sheng (Journal of Marine Science and Engineering, 2022)
Being a powerful strategy to preclude drag and achieve hydrodynamic invisibility, flow field manipulation is attracting widespread attention. In this investigation, we introduce a systematic set of arbitrary-space divide-and-conquer transformation strategies to design complex hydrodynamic cloaks. This theory removes the difficulties associated with the analytic description of complicated and irregular structures to construct hydrodynamic cloaks by adopting the divide-and-conquer algorithm and reconfiguring strategies. It also provides an approach for redistributing the flow field energy and guiding the fluid flow as desired. The proposed theory not only opens up new ideas for improving the speed and concealment of marine vehicles but also provides a new strategy for ensuring the safety of aquatic and underwater structure operations.

Spatial and Seasonal Variations in the Stable Isotope Values and Trophic Positions of Dominant Zooplankton Groups in Jiaozhou Bay, China - Zhixin Ke; Ruofei Li; Danting Chen; Chunyu Zhao; Yehui Tan (Frontiers in Marine Science, 2022)
The spatial and seasonal distributions of stable carbon and nitrogen isotopes (δ 13 C and δ 15 N) in dominant zooplankton groups were investigated in Jiaozhou Bay. Zooplankton δ 13 C values ranged from −22.89‰ to −15.86‰, and δ 15 N values ranged from 3.18‰ to 13.57‰, respectively. The δ 13 C and δ 15 N values generally followed the order of small zooplankton < large calanoids < small Sagitta < large Sagitta . Spatial distribution patterns of zooplankton δ 13 C and δ 15 N values varied in different seasons. Our results suggested that the spatial variation of δ 13 C was mainly controlled by terrigenous organic matter (OM) input and phytoplankton biomass, but water temperature may have played a key role in the seasonal variation of δ 13 C. In spring, the high phytoplankton biomass might increase the δ 13 C value of small zooplankton in the inner bay. During other seasons, the δ 13 C values of zooplankton generally increased from the inner bay to the outer bay, which might be associated with the influence of 13 C-depleted terrigenous OM carried by the river discharge. Small zooplankton stable isotope values were significantly correlated with that of particulate organic matter (POM). The influence of anthropogenic nutrient input on isotopic baseline can be cascaded to the zooplankton, and the effect might be weak at higher trophic levels. The Bayesian standard ellipse areas of dominant zooplankton groups were generally smallest in the winter, suggesting a narrow niche width during that time. The niche partition between small zooplankton, large calanoids, and Sagitta was most distinct in winter, and followed by summer. The relative trophic level of Sagitta ranged from 2.23 to 4.01, which generally declined from the inner bay to the outer bay during the spring, autumn, and winter seasons. High anthropogenic nutrient loading might reduce the difference in trophic niches among zooplankton groups. This study provided detailed information on the distribution of zooplankton δ 13 C and δ 15 N in a coastal bay, which will be useful for understanding the anthropogenic influence on the ecosystem structure and function.

Toxicity and Bioaccumulation of Copper in Phaeodactylum tricornutum Under Different Macronutrient Conditions - Beibei Zhou; Yue Zou; Jie Ma; Yanping Li; Ke Pan (Frontiers in Marine Science, 2022)
In this study, we investigated cell physiological and biochemical responses to copper (Cu) accumulation in the marine diatom Phaeodactylum tricornutum under different nitrogen (N) and phosphorus (P) conditions. Cells with sufficient N and P (+N+P) showed the highest total Cu concentrations and displayed a higher metal-tolerance ability. In the +N+P treatments, 36.5% of dissolved Cu was adsorbed on the frustules (cell walls), 54.9% was occluded in organelles, and 8.6% was in the soluble fraction. In comparison, cells with N and/or P shortages (+N−P, −N+P, and −N−P) adsorbed 10.8–13.1% of the total Cu onto their cell walls, 74.5–80% was occluded in organelles, and 9.2–12.4% was in the soluble fraction. The Cu 2+ influx on the +N+P cell wall was faster due to sufficient metal ligands on the cell walls and up-regulated metal-related transporters. A significant increase in protein content occurred under N and/or P shortages, which was accompanied by the inhibition of the antioxidative enzymatic system and cell membrane damage. Our findings indicate that N and P play an important role in both Cu adsorption (cell surface) and uptake (intracellular), and they provide multifaceted evidence of the Cu acquisition mechanism in P. tricornutum under different macronutrient conditions.

Predicting long-term hydrological change caused by climate shifting in the 21st century in the headwater area of the Yellow River Basin - Jingyi Hu; Yiping Wu; Pengcheng Sun; Fubo Zhao; Ke Sun; Tiejian Li; Bellie Sivakumar; Linjing Qiu; Yuzhu Sun; Zhangdong Jin (Stochastic Environmental Research and Risk Assessment, 2022)

Influence Mechanism of Mine Pressure on Coal Seam Gas Emission During Mining - Chaowen Hu; Qian Li; Yilong Wang; Yongyuan Li; Yaqian Wang; Ke Chang (Geotechnical and Geological Engineering, 2022)

Potential application of Fusarium fungal strains (Fusarium sp. FP, Arthrinium sp. FB, and Phoma sp. FR) for removal of Tl (I) ions from water - Jianying Mo; Yonghui Liu; Xiaoning Gao; Shuyi Zhou; Yirong Deng; Yanyang Ke; Lihu Peng; Huosheng Li; Sihao Chen; Jianyou Long (Environmental Science and Pollution Research, 2022)

FLO8 deletion leads to decreased adhesion and virulence with downregulated expression of EPA1, EPA6, and EPA7 in Candida glabrata - Jun-Tao Zhao; Ke-Zhi Chen; Jin-Yan Liu; Wei-Hua Li; Yu-Zhu Wang; Lu-Ling Wang; Ming-Jie Xiang (Brazilian Journal of Microbiology, 2022)

Isolation and characterization of 45 SNP markers in Triplophysa tenuis - Ya Liu; Yeyu Chen; Jiansheng Lai; Hongyu Ke; Zhongmeng Zhao; Han Zhao; Xiaoyun Wu; Jian Zhou; Qiang Li (Conservation Genetics Resources, 2022)

Mitigation of microbial corrosion by Cu addition to X65 pipeline steel by Pseudomonas aeruginosa MCCC 1A00099 - Yuchen Li; Xianbo Shi; Jiguang Li; Yunpeng Zeng; Minggang Shen; Wei Yan; Ke Yang (Archives of Microbiology, 2022)

Comparison of different inversion methods of D-T2 two-dimensional nuclear magnetic resonance logging and applicability analysis - Cheng-Lin Li; Mao-Jin Tan; Ke-Wen Wang; Feng Zhou; Ying-Ming Liu; Hai-Tao Zhang; Li-Zhi Xiao (Applied Geophysics, 2022)

Clinico-pathological features and mutational spectrum of 16 nemaline myopathy patients from a Chinese neuromuscular center - Xi Yin; Chuanqiang Pu; Zhenfu Wang; Ke Li; HuiFang Wang (Acta Neurologica Belgica, 2022)
Nemaline myopathy (NM) is a congenital myopathy of great heterogeneity, characterized by the presence of rods in the cytoplasm of muscle fibers. The samples of 16 nemaline myopathy patients diagnosed by characteristically pathological features went through whole exon sequencing. Clinico-pathological and genetic features of the cases were systematically analyzed. According to the classification of nemaline myopathy by ENMC, 8 cases are typical congenital subtype, 6 cases are childhood/juvenile onset subtype and 2 case are adult onset subtype. In histological findings, characteristic purple-colored rods are discovered under modified gömöri trichrome staining (MGT). Electron microscopy revealed the presence of high electron-dense nemaline bodies around the submucosa and the nucleus nine patients (9/16 56.3%) were detected pathogenic causative mutations, among whom mutations in the NEB gene were the most frequent (6 patients, 66.7%). KBTBD13 gene mutation was discovered in two patients and ACTA1 gene mutation was discovered in 1 patient. Nemaline myopathy is a congenital myopathy with highly clinico-pathological and genetic heterogeneity. NEB gene mutation is the most common mutation, in which splicing change c.21522 +3A > G is hotspot mutation in Chinese NM patients.

Community Structure of Benthic Macrofauna and the Ecological Quality of Mangrove Wetlands in Hainan, China - Ping Li; Jingli Liu; Jiankun Bai; Yifan Tong; Yuchen Meng; Xiaoping Diao; Ke Pan; Xiaoshan Zhu; Guanghui Lin (Frontiers in Marine Science, 2022)
Few studies have systematically assessed the ecological status of mangrove wetlands following the stress of anthropogenic activities in China. This study investigated the spatial and seasonal distribution of benthic macroinvertebrate communities and assessed the ecological quality of mangrove habitats on an island scale in Hainan, China (containing the third largest mangrove area of China and the highest mangrove species richness). For the benthic macrofauna community structure, a total of 102 macrobenthic taxa belonging to 50 families were identified, with Crustaceans, Molluscs, Polychaetes, and Oligochaeta having relative abundances of 52.3%, 36.1%, 10.8%, and 0.8%, respectively. Decapoda and Gastropoda dominated the benthic community abundance. Non-metric multidimensional scaling and an analysis of similarities revealed significantly different macroinvertebrate assemblages among the regions during the two seasons. The South mangroves had the lowest macrofauna species numbers, biodiversity, richness, and abundance. The macrofaunal species richness, Shannon index, Margalef index, abundance, and biomass markedly affected by region and season. As indicated by the biotic indices AMBI (AZTI’s Marine Biotic Index) and M-AMBI, more than half of the mangrove habitats on Hainan Island were slightly to heavily disturbed and had poor to moderate ecological quality. Our results recommend long-term monitoring for evaluating the quality status of mangrove wetlands and avoiding extensive land-use conversion of mangroves. Holistic approaches considering ecological characteristics and combining information on both floral and faunal functionality would contribute to the effective management and conservation of mangroves in disturbed areas.

Mutation of Beclin1 acetylation site at K414 alleviates high glucose-induced podocyte impairment in the early stage of diabetic nephropathy by inhibiting hyperactivated autophagy - Jun Xu; Yujie Deng; Yingying Ke; Yunxia Zhu; Ping Wang; Qing Yu; Chengqian Li; Bimin Shi (Molecular Biology Reports, 2022)

The Effects of Ground and Treadmill Running on Energy Metabolism and Muscle Contractile Properties: A Randomized Cross-Over Study - Yuan Zhou; Jian-gang Chen; Xiao-long Li; Xin-liang Pan; Yi-zheng Zhou; Zheng-ao Li; Zhi-cheng Liang; Jia-min Long; Ming-ze Qin; Jing Zhang; Bing Shi; Bing-jun Wan; et al. (Journal of Science in Sport and Exercise, 2022)
Purpose This study aimed to compare the effects of ground and treadmill running on energy metabolism and muscle contractile properties, providing a basis for the general public to choose running venues. Methods Ten male college students (age, 20.10 ± 1.53 years; height, 176.20 ± 5.49 cm; weight, 72.14 ± 8.25 kg; body fat percent, 12.41% ± 4.65%) were recruited in this study. Energy expenditure (EE) was measured using the accelerometer (GT9X) combined with specific estimation equations. Average heart rate (HR) was measured using a heart rate band (Polar). Muscle contractile properties were assessed by measuring muscle displacement (Dm) and contraction velocity (Vc) using tensiomyography (TMG-S1). Blood glucose (Glu) and lactate (Lac) were measured by portable devices (eB-G and Lactate Scout). The running speed was 9 km/h and the duration was 25 min. Two-way ANOVA (protocol × time) was used to analyze the effect of running protocols on energy metabolism and muscle contractile properties. Results EE of treadmill running was significantly higher than EE of ground running (protocol main effect, P < 0.001), and HR of treadmill running was significantly higher than that of ground running in the first testing time (protocol simple effect, P = 0.026; protocol × time interaction P = 0.043). The decrease in Dm of the rectus femoris after treadmill running was significantly higher than that of ground running (protocol main effect, P = 0.009). The interaction of different running protocols and testing times on Lac was significant ( P = 0.025), but all results of the simple effects analysis were not statistically significant ( P > 0.05). Conclusion Our study found a difference in energy expenditure between treadmill and ground running at 9 km/h with duration of 25 min. In addition, treadmills are more likely to cause a decrease in muscle displacement distance of the rectus femoris measured after exercise than ground running. Future studies are needed to further investigate whether the differences are induced by internal metabolism or the environmental conditions of running.

Novel EST-SSRs for an important quarantine pest Liriomyza sativae (Diptera: Agromyzidae) and their cross-species transferability - Tiansheng Liu; Xue Zhan; Jinyu Li; Fushi Ke; Xiangyu Zhu; Yanting Chen; Weiyi He; Shijun You (Applied Entomology and Zoology, 2022)

Nutrient driven transcriptional changes during phage infection in an aquatic Gammaproteobacterium - Emelie Nilsson; Ke Li; Matthias Hoetzinger; Karin Holmfeldt (Environmental Microbiology, 2022)
Summary Phages modulate bacterial metabolism during infection by regulating gene expression, which influences aquatic nutrient cycling. However, the effects of shifting nutrient regimes are less understood. Here, we analyzed transcriptomes of an ecologically relevant Gammaproteobacterium and its lytic phage in high (HNM) and low (LNM) nutrient medium. Despite different infection characteristics, including reduced burst size and longer latent period in LNM, the phage had a fixed expression profile. Bacterial transcription was instead different depending on nutrient regime, with HNM bacteria focusing on growth while LNM bacteria focused on motility and membrane transport. Additionally, phage infection had a larger effect on bacterial gene expression in LNM compared to HNM, e.g. suppressing increased iron uptake and altering expression of phosphorus uptake genes. Overall, phage infection influenced host metabolism more in LNM, which was more similar to natural conditions, emphasizing the importance of considering natural conditions to understand phage and host ecology.

Isolation and characterization of 112 SNP markers in Yellowfin seabream (Acanthopagrus latus) using RAD sequencing - Ke-Cheng Zhu; Ya-Ling Li; Wei-Bin Wu; Bao-Suo Liu; Hua-Yang Guo; Nan Zhang; Liang Guo; Dian-Chang Zhang (Conservation Genetics Resources, 2022)

Experimental Investigation of Wave-Induced Forces on a Large Quasi-Elliptical Cylinder during Extreme Events - Zhiying Yang; Hao Ding; Ke Li; Liang Cheng; Bo Huang; Qingyang Ren (Journal of Marine Science and Engineering, 2022)
Large quasi-elliptical cylinders are extensively used in ocean engineering. To enhance a better understanding of the hydrodynamic wave force on such quasi-elliptical cylinders during extreme events, a series of experiments on extreme wave interaction with a quasi-elliptical cylinder were conducted. A series of waves with various wave heights, wave periods, and wave incident directions were tested to investigate the wave parameter effect and wave directionality effect on the wave forces on the quasi-elliptical structure. The experimental results indicate that the extreme wave-induced forces on the quasi-elliptical cylinder are strongly correlated to the wave period and wave incident direction. The peak forces on the quasi-elliptical model do not vary monotonically with the increasing wave period but show an increase followed by a decrease. Both the longitudinal and transversal forces are significantly increased when the wave incident direction changes from 0° to 45° and the wave directionality effect is enhanced when the wave period is decreased. Additionally, the inertial force equation was applied to the wave force estimation for such quasi-elliptical cylinders, and the inertia coefficient CM was fitted based on the experimental results of α = 0°.

Quorum Quenching Bacteria Bacillus velezensis DH82 on Biological Control of Vibrio parahaemolyticus for Sustainable Aquaculture of Litopenaeus vannamei - Xiaohui Sun; Jia Liu; Shijing Deng; Renhe Li; Wenhua Lv; Shufeng Zhou; Xu Tang; Yun-zhang Sun; Mingyue Ke; Kunming Wang (Frontiers in Marine Science, 2022)
Aquatic pathogens such as Vibrio parahaemolyticus cause a bacterial infection that reduces the economic benefits of aquaculture and affects the food quality and safety of human beings. Quorum quenching (QQ) is considered a novel strategy of microbial antagonism that inhibits pathogens and reduces the abuse of antibiotics. This study investigates a QQ bacterial strain, Bacillus velezensis DH82 from the deep sea Yap trench, in vitro to examine the effects of DH82 and its functional products against V. parahaemolyticus , focusing on the Quorum sensing (QS) regulation and the inhibition of pathogenicity and bacterial growth. The study also conducted in vivo investigation in the aquaculture of Litopenaeus vannamei challenged with V. parahaemolyticus by immersion and injection challenge. The results of the QS regulator transcription level demonstrated the multiple QQ enzymes in DH82 regulated the pathogenicity but could not fully control the biofilm formation; the effective antibacterial activity of extracellular peptides on microbial antagonism verified the inhibition on bacterial growth of V. parahaemolyticus . The in vivo experiment in aquaria demonstrated the effective enrichment of DH82 and inhibition of Vibrio in both the aquatic system and the shrimp intestine. The dietary DH82 relieved the negative effect of Vibrio on the activity of enzyme acid phosphatase (ACP), alkaline phosphatase (AKP), superoxide dismutase (SOD) under challenge of Vibrio pathogens, and was not harmful to host according to lysozyme (LZM) activity. DH82 also ameliorated the damage to the intestine and muscles induced by V. parahaemolyticus infection according to tissue imaging. Though DH82 did present some dose-dependent adverse effects to the host, the findings revealed the effective QQ and antibacterial activity of DH82 on emerging biocontrol against V. parahaemolyticus , therefore indicating the potential application of DH82 as a biological control reagent in the sustainable and green production of aquaculture.

Evaluation of the Bioavailability and Health Risks of Cadmium in Potato Using Three In Vitro Methods - Xue He; Ke Liu; Wei Li; Jie Zhang; Chun Mao; Jihong Feng (Water, Air, & Soil Pollution, 2022)

The Mechanism of Stem Cell Aging - Liangyu Mi; Junping Hu; Na Li; Jinfang Gao; Rongxiu Huo; Xinyue Peng; Na Zhang; Ying Liu; Hanxi Zhao; Ruiling Liu; Liyun Zhang; Ke Xu (Stem Cell Reviews and Reports, 2022)
Stem cells have self-renewal ability and multi-directional differentiation potential. They have tissue repair capabilities and are essential for maintaining the tissue homeostasis. The depletion of stem cells is closely related to the occurrence of body aging and aging-related diseases. Therefore, revealing the molecular mechanisms of stem cell aging will set new directions for the therapeutic application of stem cells, the study of aging mechanisms, and the prevention and treatment of aging-related diseases. This review comprehensively describes the molecular mechanisms related to stem cell aging and provides the basis for further investigations aimed at developing new anti-stem cell aging strategies and promoting the clinical application of stem cells.

Microscopic Investigation of Rock Direct Tensile Failure Based on Statistical Analysis of Acoustic Emission Waveforms - Zhenghu Zhang; Ke Ma; Hua Li; Zhiliang He (Rock Mechanics and Rock Engineering, 2022)

Positive microbial legacy and short-term clonal plasticity aid grazing tolerance of a widespread grass species - Xiliang Li; G. Kenny Png; Shixian Sun; Hongxiao Shi; Ke Jin; Yuanheng Li (Plant and Soil, 2022)

Transcriptome of visceral adipose tissue identifies an inflammation-related ceRNA network that regulates obesity - Ganbin Li; Haoyu Zhang; Ke Cao; Zhiwei Zhai; Zhenjun Wang; Lei Yang; Jiagang Han (Molecular and Cellular Biochemistry, 2022)

Complete Depletion of Primordial Germ Cells Results in Masculinization of Monopterus albus, a Protogynous Hermaphroditic Fish - Mingxi Hou; Ke Feng; Hongrui Luo; Yinjun Jiang; Wen Xu; Yongming Li; Yanlong Song; Ji Chen; Binbin Tao; Zuoyan Zhu; Wei Hu (Marine Biotechnology, 2022)

EV-T synergizes with AZD5582 to overcome TRAIL resistance through concomitant suppression of cFLIP, MCL-1, and IAPs in hepatocarcinoma - Kui Su; Qian Yuan; Huan Hou; Changhong Ke; Chaohong Huang; Shuyi Li; Jianwu Sun; Xin Yuan; Yue Lin; Yiqing Chen; Huijuan Xin; Xiaoping Liang; et al. (Journal of Molecular Medicine, 2022)

Genetic diversity and population structure of Curcuma alismatifolia Gagnep. accessions revealed by SSR markers - Hui-Wen Yu; Ling-Jun Ke; Yi-Lan Xiao; Si-Jia Chen; Yuan-Yuan Li; Qi-Lin Tian; Yun-He Li; Jin-Shui Lin; Luan-Mei Lu (Genetic Resources and Crop Evolution, 2022)

Association of temperature variability with the risk of initial outpatient visits for allergic rhinitis: a time-series study in Changchun - Man Xu; Pan Ke; Ruoling Chen; Ping Hu; Bing Liu; Jian Hou; Li Ke (Environmental Science and Pollution Research, 2022)

Digital soil mapping of soil total nitrogen based on Landsat 8, Sentinel 2, and WorldView-2 images in smallholder farms in Yellow River Basin, China - Yiming Xu; Bin Li; Xianbao Shen; Ke Li; Xinyue Cao; Guannan Cui; Zhiliang Yao (Environmental Monitoring and Assessment, 2022)

Morphologic changes of simple star dunes during the growth process in Dunhuang, China - Zhi-shan An; Ke-cun Zhang; Li-hai Tan; Qing-he Niu; Ben-li Liu; Bai-cheng Niu (Journal of Mountain Science, 2022)

Mass Transfer during Hematitization and Implications for Uranium Mineralization in the Zoujiashan Deposit, Xiangshan Volcanic Basin - Teng Deng; Guoxiang Chi; Xiongjie Zhang; Zenghua Li; Deru Xu; Shengmiao Li; Pengfei Du; Pei Shang; Shaohao Zou; Wanpeng Zhou; Ke Xu; Hai Yan; et al. (Journal of Earth Science, 2022)

Genomic analysis of Acinetobacter phage BUCT629, a newly isolated member of the genus Obolenskvirus - Ke Han; Yinuo Zhu; Fei Li; Mengzhe Li; Xiaoping An; Lihua Song; Huahao Fan; Yigang Tong (Archives of Virology, 2022)

Retraction Note: Source discrimination of mine water inrush based on Elman neural network globally optimized by genetic algorithm - Xing Xu; Xingzhi Wang; Ke Li; Yuanzhi Li (Arabian Journal of Geosciences, 2022)

The Predictability of Ocean Environments that Contributed to the 2020/21 Extreme Cold Events in China: 2020/21 La Niña and 2020 Arctic Sea Ice Loss - Fei Zheng; Ji-Ping Liu; Xiang-Hui Fang; Mi-Rong Song; Chao-Yuan Yang; Yuan Yuan; Ke-Xin Li; Ji Wang; Jiang Zhu (Advances in Atmospheric Sciences, 2022)
Several consecutive extreme cold events impacted China during the first half of winter 2020/21, breaking the low-temperature records in many cities. How to make accurate climate predictions of extreme cold events is still an urgent issue. The synergistic effect of the warm Arctic and cold tropical Pacific has been demonstrated to intensify the intrusions of cold air from polar regions into middle-high latitudes, further influencing the cold conditions in China. However, climate models failed to predict these two ocean environments at expected lead times. Most seasonal climate forecasts only predicted the 2020/21 La Niña after the signal had already become apparent and significantly underestimated the observed Arctic sea ice loss in autumn 2020 with a 1–2 month advancement. In this work, the corresponding physical factors that may help improve the accuracy of seasonal climate predictions are further explored. For the 2020/21 La Niña prediction, through sensitivity experiments involving different atmospheric–oceanic initial conditions, the predominant southeasterly wind anomalies over the equatorial Pacific in spring of 2020 are diagnosed to play an irreplaceable role in triggering this cold event. A reasonable inclusion of atmospheric surface winds into the initialization will help the model predict La Niña development from the early spring of 2020. For predicting the Arctic sea ice loss in autumn 2020, an anomalously cyclonic circulation from the central Arctic Ocean predicted by the model, which swept abnormally hot air over Siberia into the Arctic Ocean, is recognized as an important contributor to successfully predicting the minimum Arctic sea ice extent.

The 2020/21 Extremely Cold Winter in China Influenced by the Synergistic Effect of La Niña and Warm Arctic - Fei Zheng; Yuan Yuan; Yihui Ding; Kexin Li; Xianghui Fang; Yuheng Zhao; Yue Sun; Jiang Zhu; Zongjian Ke; Ji Wang; Xiaolong Jia (Advances in Atmospheric Sciences, 2022)

Expansion of bilin‐based red light sensors in the subaerial desert cyanobacterium Nostoc flagelliforme - Hai‐Feng Xu; Guo‐Zheng Dai; Yu‐Jie Wang; Chao Cheng; Jin‐Long Shang; Ren‐Han Li; Ke Liu; Deqiang Duanmu; Bao‐Sheng Qiu (Environmental Microbiology, 2022)
Summary Light is the crucial environmental signal for desiccation‐tolerant cyanobacteria to activate photosynthesis and prepare for desiccation at dawn. However, the photobiological characteristics of desert cyanobacteria adaptation to one of the harshest habitats on Earth remain unresolved. In this study, we surveyed the genome of a subaerial desert cyanobacterium Nostoc flagelliforme and identified two phytochromes and seven cyanobacteriochromes (CBCRs) with one or more bilin‐binding GAF (cGMP phosphodiesterase/adenylyl cyclase/FhlA) domains. Biochemical and spectroscopic analyses of 69 purified GAF‐containing proteins from recombinant phycocyanobilin (PCB), biliverdin or phycoerythrobilin‐producing Escherichia coli indicated that nine of these proteins bind chromophores. Further investigation revealed that 11 GAFs form covalent adducts responsive to near‐UV and visible light: eight GAFs contained PCB chromophores, three GAFs contained biliverdin chromophores and one contained the PCB isomer, phycoviolobilin. Interestingly, COO91_03972 is the first‐ever reported GAF‐only CBCR capable of sensing five wavelengths of light. Bioinformatics and biochemical analyses revealed that residue P132 of COO91_03972 is essential for chromophore binding to dual‐cysteine CBCRs. Furthermore, the complement of N . flagelliforme CBCRs is enriched in red light sensors. We hypothesize that these sensors are critical for the acclimatization of N . flagelliforme to weak light environments at dawn.

Microplastic Contamination on the Beaches of South China - Bingwen Chai; Yanping Li; Li Wang; Xiao-Tan Zhang; Yi-Ping Wan; Fengyuan Chen; Jie Ma; Wenlu Lan; Ke Pan (Frontiers in Marine Science, 2022)
Microplastics (MPs) have emerged as a pollutant of significant global concern. The sandy beach is a fragile environment that deserves our special attention with regard to MP contamination, as this area is a hotspot that accumulates large quantities of plastic waste. Notably, our current understanding of the MP distribution on beaches and the scale of contamination is far from sufficient. Hence, this study investigated the occurrence and characteristics of MPs on 14 beaches along the coast of South China. The MPs were ubiquitously distributed in the sand, most were small, less than 1 mm. A total of 18 types of polymers were identified in the sand, suggesting that diverse types of MPs are present on the beaches. Polyethylene, polypropylene, and polystyrene were the dominant types of MPs in most of our sampling sites. The MP abundance was higher in the upper layers (0–20 cm) of the beach than in the deeper layers (20–40 cm) of the sampling site when characterized by depth (Yangjiang beach). Our study demonstrates the extent and severity of MP pollution on the beaches of South China and provides implications for future remediation measures. More effort is needed to clarify the vertical distribution of MPs on beaches, especially for those MPs less than 1 μm.

A review on recent advances in plasma-activated water for food safety: current applications and future trends - Qisen Xiang; Liumin Fan; Yunfei Li; Shanshan Dong; Ke Li; Yanhong Bai (Critical Reviews in Food Science and Nutrition, 2022)

Assessing the impacts of natural disasters on rice production in Jiangxi, China - Xiao Fu; Guannan Zhao; Weicheng Wu; Bin Xu; Jie Li; Xiaoting Zhou; Xinxin Ke; Yuan Li; Wenjing Li; Cuimin Zhou; Jingheng Jiang; Ming Zhang; et al. (International Journal of Remote Sensing, 2022)

Aldosterone dysregulation predicts the risk of mortality and rehospitalization in heart failure with a preserved ejection fraction - Bingbing Ke; Xin Tan; Lu Ren; Yangkai Fan; Yixin Zhang; Fengjuan Li; Qiqi Sun; Tong Liu; Lixin Jia; Yuan Wang; Jie Du (Science China Life Sciences, 2022)

Functional characterization of tyrosine decarboxylase genes that contribute to acteoside biosynthesis in Rehmannia glutinosa - Yan Hui Yang; Mu Rong Yang; Jian Yu Zhu; Ke Wei Dong; Yan Jie Yi; Rui Fang Li; Lei Zeng; Chang Fu Zhang (Planta, 2022)

MiR-10b-3p alleviates cerebral ischemia/reperfusion injury by targeting Krüppel-like factor 5 (KLF5) - Ke Sun; Jiangang Zhang; Qingcheng Yang; Jinzhao Zhu; Xiangdong Zhang; Kun Wu; Zhenhua Li; Weizheng Xie; Xue Luo (Pflügers Archiv - European Journal of Physiology, 2022)

Notch pathway inhibition mediated by arsenic trioxide depletes tumor initiating cells in small cell lung cancer - Meng-Hang Yang; Bing Li; Ke-Jie Chang (Molecular Biology Reports, 2022)

Recycling of supra-crustal materials in the rhyolites from north Sonid Youqi: implications for the crustal evolution in the southeast Central Asian Orogenic Belt - Jian-Zhou Tang; Zhicheng Zhang; Bo Liu; Shaohua Zhang; Ke Li; Qi Wang; Cong Ding (International Journal of Earth Sciences, 2022)

Association of long-term exposure to ambient air pollution with the number of tuberculosis cases notified: a time-series study in Hong Kong - Man Xu; Ping Hu; Ruoling Chen; Bing Liu; Hongying Chen; Jian Hou; Li ke; Jiao Huang; Hairong Ren; Hui Hu (Environmental Science and Pollution Research, 2022)

Source apportionment and ecological and health risk mapping of soil heavy metals based on PMF, SOM, and GIS methods in Hulan River Watershed, Northeastern China - Yiming Xu; Xianxia Wang; Guannan Cui; Ke Li; Yanfeng Liu; Bin Li; Zhiliang Yao (Environmental Monitoring and Assessment, 2022)

Visco − elastic − plastic creep model based on Burgers and Bingham model and its verification - Jinpeng Zhao; Zhongsheng Tan; Lei Li; Rongsen Yu; Ke Lei (Arabian Journal of Geosciences, 2022)

Susceptibility of patients with chronic obstructive pulmonary disease to heart rate difference associated with the short-term exposure to metals in ambient fine particles: A panel study in Beijing, China - Ke Gao; Xi Chen; Xiaoying Li; Hanxiyue Zhang; Mengxiao Luan; Yuan Yao; Yifan Xu; Teng Wang; Yiqun Han; Tao Xue; Junxia Wang; Mei Zheng; et al. (Science China Life Sciences, 2022)

Effect of darkness treatment on the morphology, hormone status and gene expression of developing adventitious root in apple rootstock - Ke Li; Huiyue Tian; Jiangping Mao; Abid Khan; Muhammad Mobeen Tahir; Shaohuan Li; Shiyue Chen; Yun Shao; Dong Zhang (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Sex-Specific Genomic Region Identification and Molecular Sex Marker Development of Rock Bream (Oplegnathus fasciatus) - Jie Gong; Bijun Li; Ji Zhao; Zhixiong Zhou; Qiaozhen Ke; Qihui Zhu; Dongdong Xu; Tao Zhou; Peng Xu (Marine Biotechnology, 2022)

Effects of dietary carbohydrate to lipid ratios on growth, biochemical indicators, lipid metabolism, and appetite in Chinese perch (Siniperca chuatsi) - Di Peng; Xu-Fang Liang; Farui Chai; Hexiong Feng; Jiao Li; Shulin Tang; Ke Lu; Qiwei Zhang (Fish Physiology and Biochemistry, 2022)

Dietary exposure assessment of paralytic shellfish toxins through shellfish consumption in Shenzhen population, China - Yan Zhou; Shenpan Li; Jianying Zhang; Jinzhou Zhang; Zhou Wang; Liubo Pan; Baiqiang Huang; Ke Huang; Xiao Chen; Qionghui Zhao; Tianjiu Jiang; Jianjun Liu (Environmental Science and Pollution Research, 2022)

Apatite chemistry as a petrogenetic–metallogenic indicator for skarn ore-related granitoids: an example from the Daye Fe–Cu–(Au–Mo–W) district, Eastern China - Run-Jie Zhou; Guang Wen; Jian-Wei Li; Shao-Yong Jiang; Hao Hu; Xiao-Dong Deng; Xin-Fu Zhao; Dai-Rong Yan; Ke-Tao Wei; Heng-An Cai; Shi-Chao Shang; Bai-Cun Li; et al. (Contributions to Mineralogy and Petrology, 2022)

The brain functional connectivity in the default mode network is associated with self-efficacy in young adults - Xi Wang; Qunlin Chen; Yu Li; Ke Ding; Jiang Qiu (Brain Imaging and Behavior, 2022)

miR-181b-5p Promotes the Progression of Cholangiocarcinoma by Targeting PARK2 via PTEN/PI3K/AKT Signaling Pathway - Zhe-Long Jiang; Fu-Xing Zhang; Hong-Liang Zhan; He-Jun Yang; Si-Yu Zhang; Zhao-Hui Liu; Yi Jiang; Li-Zhi Lv; Rui-Sheng Ke (Biochemical Genetics, 2022)

Swimming behaviour of silver carp ( Hypophthalmichthys molitrix ) in response to turbulent flow induced by a D ‐cylinder - Senfan Ke; Zhiying Tu; Elsa Goerig; Junjun Tan; Bixin Cheng; Zhimin Li; Xiaotao Shi (Journal of Fish Biology, 2022)
Turbulence is a complex hydraulic phenomenon which commonly occurs in natural streams and fishways. Riverine fish are subjected to heterogeneous flow velocities and turbulence, which may affect their movements and ability to pass the fishways. However, studies focusing on fish response to turbulent flows are lacking for many species. Here we investigate the effects of the turbulence created by a vertical half‐cylinder of various diameters (1.9, 2.5, 3.2 and 5.0 cm) on the swimming ability and behaviour of silver carp, Hypophthalmichthys molitrix . The large D‐cylinders (3.0 and 5.0 cm) create specific vorticity and reduced velocities areas in their vicinity, which favours flow refuging behaviours (FRBs) and thus increased relative critical swimming speeds ( U rcrit , BL/s) of silver carp, by comparison to free‐flow conditions and cylinders of smaller diameter (1.9 and 2.5 cm). The flow speed at which silver carp maximized FRBs such as Karman gaiting downstream of the cylinder, holding position in the bow wake or entraining on the side ranged from 40 to 70 cm s −1 , depending on fish body size. When holding station near a cylinder under optimal flow speeds, the distance between the fish and the cylinder is related to the size of the fish, but also to the size of the cylinder and the produced vortices. The optimal holding region in the drag wake of the cylinder ranged from 28 to 40 cm downstream of the centre of the cylinder, depending on the size of the fish. Smaller fish, however, tend to use the reduced velocities areas located in the bow wake of the large cylinders. We hypothesize that fish will display FRBs, including maintaining a Karman gait in turbulent flow, when the ratio of the cylinder diameter to their body length is between 1:3 and 1:4. They also match their tail beat frequency to the vortex shedding frequency of the cylinder. Our results provide a better understanding of how silver carp respond to turbulent flows around physical structures, with implications for the design of nature‐like fishways or exclusion devices in both its native and invasive ranges.

Oxidation of organoarsenicals and antimonite by a novel flavin monooxygenase widely present in soil bacteria - Jun Zhang; Jian Chen; Yi‐Fei Wu; Zi‐Ping Wang; Ji‐Guo Qiu; Xiao‐Long Li; Feng Cai; Ke‐Qing Xiao; Xiao‐Xu Sun; Barry P. Rosen; Fang‐Jie Zhao (Environmental Microbiology, 2022)
Summary Arsenic can be biomethylated to form a variety of organic arsenicals differing in toxicity and environmental mobility. Trivalent methylarsenite (MAs(III)) produced in the methylation process is more toxic than inorganic arsenite (As(III)). MAs(III) also serves as a primitive antibiotic and, consequently, some environmental microorganisms have evolved mechanisms to detoxify MAs(III). However, the mechanisms of MAs(III) detoxification are not well understood. In this study, we identified an arsenic resistance ( ars ) operon consisting of three genes, arsRVK , that contribute to MAs(III) resistance in Ensifer adhaerens ST2. ArsV is annotated as an NADPH‐dependent flavin monooxygenase with unknown function. Expression of arsV in the arsenic hypersensitive Escherichia coli strain AW3110 Δars conferred resistance to MAs(III) and the ability to oxidize MAs(III) to MAs(V). In the presence of NADPH and either FAD or FMN, purified ArsV protein was able to oxidize both MAs(III) to MAs(V) and Sb(III) to Sb(V). Genes with arsV ‐like sequences are widely present in soils and environmental bacteria. Metagenomic analysis of five paddy soils showed the abundance of arsV ‐like sequences of 0.12–0.25 ppm. These results demonstrate that ArsV is a novel enzyme for the detoxification of MAs(III) and Sb(III) and the genes encoding ArsV are widely present in soil bacteria.

Myrothecol A, a new alkylresorcinol with cytotoxicity from Myrothecium sp. - Zhen-Hua Li; Hui-Yuan Yang; Wen-Ting Zhu; Dong-Dong Jing; Shi-Neng Li; Peng-Ke Yan (Natural Product Research, 2022)

Transcriptomic and physiological analysis reveals interplay between salicylic acid and drought stress in citrus tree floral initiation - Faiza Shafique Khan; Zhi-Meng Gan; En-Qing Li; Meng-Ke Ren; Chun-Gen Hu; Jin-Zhi Zhang (Planta, 2022)

An antagonistic effect of elevated CO2 and warming on soil N2O emissions related to nitrifier and denitrifier communities in a Chinese wheat field - Yuan Liu; Ke Gao; Zonghao Guo; Xiaoyu Liu; Rongjun Bian; Baobao Sun; Jie Li; Junhui Chen (Plant and Soil, 2022)

Effect of exogenous abscisic acid (ABA) on the morphology, phytohormones, and related gene expression of developing lateral roots in ‘Qingzhen 1’ apple plants - Xiaoyun Zhang; Muhammad Mobeen Tahir; Shaohuan Li; Ting Tang; Jiangping Mao; Ke Li; Yun Shao; Weiwei Yang; Jianxin Niu; Dong Zhang (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Piezo1 mediates endothelial atherogenic inflammatory responses via regulation of YAP/TAZ activation - Ying Yang; Danyang Wang; Chunxiao Zhang; Wenqing Yang; Chao Li; Zichen Gao; Ke Pei; Yunlun Li (Human Cell, 2022)

Genetic improvement of grain quality traits in indica inbred rice cultivars developed in South China during 1956–2020 - Xin-Qiao Zhou; Da-Gang Chen; Jie Guo; Ping-Li Chen; Li-Jun Li; Ke Chen; You-Ding Chen; Chuan-Guang Liu; Ze-Min Zhang (Euphytica, 2022)

The effects of immersive garden experience on the health care to elderly residents with mild-to-moderate cognitive impairment living in nursing homes after the COVID-19 pandemic - Chung-Heng Hsieh; Cheng-Min Chen; Ju-Yuan Yang; Yen-Ju Lin; Man-Li Liao; Ke-Hsin Chueh (Landscape and Ecological Engineering, 2022)

Identification of bacterial blight resistance genes in rice landraces from Yunnan Province, China - Caimei Zhao; Fuyou Yin; Ling Chen; Dingqin Li; Suqin Xiao; Qiaofang Zhong; Bo Wang; Xue Ke; Jian Fu; Xiang Li; Yue Chen; Lingxian Wang; et al. (Australasian Plant Pathology, 2022)
Bacterial blight (BB), a serious bacterial disease caused by pathogen Xanthomonas oryzae pv. oryzae ( Xoo ) affects rice growth and yield. Yunnan Province is regarded as a center of rice diversity in China and indeed the world, and has abundant rice landrace resources, which may offer prospective candidate donors in rice improvement and breeding. In this study, a set of 200 rice landraces were evaluated to determine their resistance to 10 pathogenic Xoo strains resistance by the leaf-clipping method. The results indicated that the tested rice landraces had different resistance levels against different Xoo strains. Multiple comparisons showed that the Xoo strain PXO99 was virulent to the tested rice landraces. Sixty-six rice landraces conferred resistance against at least one Xoo strain. These resistant rice landraces screened were then performed the presence of 14 cloned BB resistance genes by closely linked molecular markers and designed specific primers. The results showed that none of these resistant accessions contained xa13 , Xa21 , Xa27 , and Xa45(t) homologous fragments, while 9, 24, 4, 7, 9, 15, 1, 5, 4 and 27 accessions contained Xa1 , Xa2/Xa31(t) , Xa14 , Xa3/Xa26 , Xa4 , xa5 , Xa7 , Xa10 , Xa23 and xa25 homologous fragments, respectively. Sequence analysis further revealed that nucleotide variations around functional nucleotide polymorphisms region were observed within these accessions containing the Xa1 , Xa2/Xa31(t) , Xa14 , Xa3/Xa26 , Xa4 , xa5 , Xa10 , Xa23 and xa25 homologous fragments. These results along with phenotypic resistance spectrum supported that these accessions carried nine resistance homologous genes. Only one accession (Qishanggu_Wenshan) carried the Xa7 resistance gene. We also found that some resistant rice landraces, especially Xilandigu_Baoshan, and Laoyaling_Lincang without the above resistance genes, which mediated broad spectrum resistance to multiple Xoo strains, were identified as potential sources for breeding rice lines resistance to BB.

Rock mechanical failure characteristics and energy evolution analysis of coal-rock combination with different dip angles - Wenbing Shen; Weijian Yu; Bao Pan; Ke Li (Arabian Journal of Geosciences, 2022)

Anti-inflammatory Dendranacetylene A, a new polyacetylene glucoside from the flower of Chrysanthemum morifolium Ramat - Meng Li; Mengnan Zeng; Jingke Zhang; Jingya Shi; Jinjin Lv; Yingying Tang; Xiao-ke Zheng; Wei-sheng Feng (Natural Product Research, 2021)

Lathyrane diterpenoids from Jatropha podagrica and their antitumor activities in human osteosarcoma cells - Han-Tao Yuan; Qun-Feng Li; Tian Tian; Chun-Yan Zhang; Zou-Qin Huang; Chun-Xiang Fan; Ke Mei; Jie Zhou; Xiao-Xiang Zhai; Si-Bo Li; Jian-Yong Zhu (Natural Product Research, 2021)

Hydrogen Sulfide Maintains Good Nutrition and Delays Postharvest Senescence in Postharvest Tomato Fruits by Regulating Antioxidative Metabolism - Ting-Ying Zhong; Gai-Fang Yao; Sha-Sha Wang; Ting-Ting Li; Ke-Ke Sun; Jun Tang; Zhong-Qin Huang; Feng Yang; Yan-Hong Li; Xiao-Yan Chen; Lan-Ying Hu; Hua Zhang; et al. (Journal of Plant Growth Regulation, 2021)

M1 macrophages-derived exosomes miR-34c-5p regulates interstitial cells of Cajal through targeting SCF - Su Xu; Jinhai Zhai; Ke Xu; Xingguo Zuo; Chenghua Wu; Tao Lin; Li Zeng (Journal of Biosciences, 2021)

Mechanical Aspects of Construction of New TBM Tunnel Under Existing Structures - Wu Ke; Zhang zheng; Li Shuchen; Zhou leisheng; Zhao Jiahui; Zheng Yang (Geotechnical and Geological Engineering, 2021)
It is inevitable for the construction of subways to pass under the existing structures in the city; this will cause settlement of the existing structures and affect their safety. The soil is a complex mixture, and hence it is difficult to determine the damage caused by construction using tunnel boring machine (TBM) method to the stress balance of the surrounding soil. Normally, settlement and uplift of the surface are caused during tunneling . Therefore, large-scale 3D simulations are needed to study the interaction between mechanically driven tunnel construction and the surrounding soil to estimate the expected settlement and related damage risks to the existing structures, especially in tunnel construction in urban areas. Qingdao Metro Line 1 in the Haixiao section (Xiaocunzhuang and Haiboqiao stations) was taken up as the research object to study the trend and degree of the effect of TBM tunnel construction using the numerical simulation software Midas GTS NX. The numerical simulation results and measured data were used for the reliability analysis to study the influence of different digging speeds and pressures in TBM construction on ground subsidence, and the effect of vibrations generated at the tunnel face by the TBM cutter head on the ground structure. It is shown that when other factors remain unchanged, the faster the driving speed, the smaller the ground settlement; the higher the surrounding rock pressure, the smaller the ground settlement. The vibration of the ground structure caused by the TBM cutter head complies with the relevant specifications. During construction, the driving parameters should be selected suitably depending on the available budget.

Correction to: Enhanced adsorption of phosphorus in soil by lanthanum-modified biochar: improving phosphorus retention and storage capacity - Di Zhao; Yuan Luo; Yi-yang Feng; Qiu-ping He; Li-sheng Zhang; Ke-qiang Zhang; Feng Wang (Environmental Science and Pollution Research, 2021)

Risk assessment of non-point source pollution based on landscape pattern in the Hanjiang River basin, China - Yi-wen Liu; Jia-ke Li; Jun Xia; Gai-rui Hao; Fang-Yenn Teo (Environmental Science and Pollution Research, 2021)

Nano-selenium alleviating the lipid metabolism disorder of LMH cells induced by potassium dichromate via down-regulating ACACA and FASN - Yuxuan Peng; Hao Li; Ke Shen; Wen Pan; Jiabin Zhang; Donghai Zhou (Environmental Science and Pollution Research, 2021)

Enhanced adsorption of phosphorus in soil by lanthanum-modified biochar: improving phosphorus retention and storage capacity - Di Zhao; Yuan Luo; Yi-yang Feng; Qiu-ping He; Li-sheng Zhang; Ke-qiang Zhang; Feng Wang (Environmental Science and Pollution Research, 2021)

A multi-emission analysis of organic and inorganic pollutants during the combustion of sludge with high and low calorific value coals - Jingyu Huang; Prince Atta Opoku; Li Guang; Li Ke; Eyram Norgbey (Environmental Science and Pollution Research, 2021)

Laboratory and field investigations of different bolting configurations for coal mine roadways in weak coal strata - Weijian Yu; Genshui Wu; Bao Pan; Chunlai Wang; Ke Li; Ze Liao (Bulletin of Engineering Geology and the Environment, 2021)

Machine learning-enhanced soil classification by integrating borehole and CPTU data with noise filtering - Te Xiao; Hai-Feng Zou; Ke-Sheng Yin; Yu Du; Li-Min Zhang (Bulletin of Engineering Geology and the Environment, 2021)

Geochemical prospectivity mapping through factor analysis and maximum entropy model: a case study in the Mila Mountain copper deposit, southern Tibet - Youhua Wei; Binbin Li; Ke Guo (Arabian Journal of Geosciences, 2021)

An improved optical flow method to estimate Arctic sea ice velocity (winter 2014–2016) - Haili Li; Changqing Ke; Qinghui Zhu; Xiaoyi Shen; Mengmeng Li (Acta Oceanologica Sinica, 2021)

Environmental contamination with SARS‐CoV ‐2 in COVID ‐19 hospitals in Wuhan, China, 2020 - Wei Liu; Dingchen Li; Chaojie Yang; Fangyan Chen; Ruizhong Jia; Leili Jia; Xinyi Xia; Shanhong Fan; Qing Tan; Yuehua Ke; Yong Chen; Haifeng Li; et al. (Environmental Microbiology, 2021)
Summary Coronavirus disease 2019 (COVID‐19) pandemic has caused high number of infections and deaths of healthcare workers globally. Distribution and possible transmission route of SARS‐CoV‐2 in hospital environment should be clarified. We herein collected 431 environmental (391 surface and 40 air) samples in the intensive care unit (ICU) and general wards (GWs) of three hospitals in Wuhan, China from February 21 to March 4, 2020, and detected SARS‐CoV‐2 RNA by real‐time quantitative PCR. The viral positive rate in the contaminated areas was 17.8% (28/157), whereas there was no virus detected in the clean areas. Higher positive rate (22/59, 37.3%) was found in ICU than that in GWs (3/63, 4.8%). The surfaces of computer keyboards and mouse in the ICU were the most contaminated (8/10, 80.0%), followed by the ground (6/9, 66.7%) and outer glove (2/5, 40.0%). From 17 air samples in the contaminated areas, only one sample collected at a distance of around 30 cm from the patient was positive. Enhanced surface disinfection and hand hygiene effectively decontaminated the virus from the environment. This finding might help understand the transmission route and contamination risk of SARS‐CoV‐2 and evaluate the effectiveness of infection prevention and control measures in healthcare facilities.

Characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with idiopathic membranous nephropathy - Lie Yang; Peng Xia; Yangzhong Zhou; Quexuan Cui; Gang Chen; Ke Zheng; Yan Qin; Xuemei Li (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Levels of polycyclic aromatic hydrocarbons in edible and fried vegetable oil: a health risk assessment study - Jin-Kui Ma; Ke Li; Xiang Li; Seham Elbadry; Amal A. Raslan; Yan Li; Zohair S. Mulla; Asmaa B. M. B. Tahoun; Waleed Rizk El-Ghareeb; Xiao-Chen Huang (Environmental Science and Pollution Research, 2021)

Standardized Dose–Response Curve (sDRC) Construction for OSL Dating of Quartz from Bohai Coast, NE China - Lei Xia; Yan Li; Yongsheng Chen; Liang Yi; Guangquan Chen; Yancheng Wang; Ke Hu (Journal of Marine Science and Engineering, 2021)
The optically stimulated luminescence (OSL) dating method promises to provide reliable ages for various Quaternary archives. Coastal sedimentation in the Bohai Sea (northeastern China) since the Middle Pleistocene has been influenced by paleoenvironmental and sea-level change, of which dating has been restricted using the OSL dating approach in multiple investigations. In this study, to establish a robust OSL chronological framework of the Bohai coastal sediments more effectively, the regional standardized dose–response curve (sDRC) was constructed for quartz OSL dating in the Bohai Coast (NE China) using two existing approaches. The sDRC-determined equivalent doses are broadly in agreement with those using the individual DRC for each sample. Data used for DRC construction of the fine-grained (FG) quartz samples are less scattered than those of the coarse-grained (CG) quartz samples, probably due to the signal-averaging effect for the FG samples, while the OSL signal of the CG quartz samples might document provenance information that yield relatively scattered distribution. The two approaches used in this study yield identical sDRCs, indicating that both the methods are applicable for sDRC construction in the Bohai Sea.

Two new phenylpropanoids and a new dihydrostilbenoid from the flower buds of Magnolia biondii pamp and their acetylcholinesterase inhibitory activities - Yan-Gang Cao; Hong-Wei Li; Bing Cao; Jian-Chao Wang; Yan-Li Zhang; Xuan Zhao; Xiao-Ke Zheng; Wei-Sheng Feng (Natural Product Research, 2021)

Master regulator NtrC controls the utilization of alternative nitrogen sources in Pseudomonas stutzeri A1501 - Zhimin Yang; Qin Li; Yongliang Yan; Xiubin Ke; Yueyue Han; Shaoyu Wu; Fanyang Lv; Yahui Shao; Shanshan Jiang; Min Lin; Yunhua Zhang; Yuhua Zhan (World Journal of Microbiology and Biotechnology, 2021)
Pseudomonas stutzeri A1501 is a model strain used to study associative nitrogen fixation, and it possesses the nitrogen regulatory NtrC protein in the core genome. Nitrogen sources represent one of the important factors affecting the efficiency of biological nitrogen fixation in the natural environment. However, the regulation of NtrC during nitrogen metabolism in P. stutzeri A1501 has not been clarified. In this work, a phenotypic analysis of the ntrC mutant characterized the roles of NtrC in nitrogen metabolism and the oxidative stress response of P. stutzeri A1501. To systematically identify NtrC-controlled gene expression, RNA-seq was performed to further analyse the gene expression differences between the wild-type strain and the ∆ ntrC mutant under nitrogen fixation conditions. A total of 1431 genes were found to be significantly altered by ntrC deletion, among which 147 associative genes had NtrC-binding sites, and the pathways for nitrogen fixation regulation, nitrogenous compound acquisition and catabolism and nitrate assimilation were discussed. Furthermore, the oxidative stress-related gene ( katB ), which was upregulated by ntrC deletion, was suggested to be a potential target gene of NtrC, thus highlighting the importance of NtrC in nitrogenase protection against oxygen damage. Based on these findings, we propose that NtrC is a high-ranking element in the regulatory network of P. stutzeri A1501 that controls a variety of nitrogen metabolic and oxidative stress responsive traits required for adaptation to complex rhizosphere environments.

Exploring spatial distributions of increments in soil heavy metals and their relationships with environmental factors using GWR - Hao Li; Peihong Fu; Yong Yang; Xue Yang; Hongjie Gao; Ke Li (Stochastic Environmental Research and Risk Assessment, 2021)

Gut-Derived Exosomes Mediate Memory Impairment After Intestinal Ischemia/Reperfusion via Activating Microglia - Xiao-Dong Chen; Jin Zhao; Xiao Yang; Bo-Wei Zhou; Zhengzheng Yan; Wei-Feng Liu; Cai Li; Ke-Xuan Liu (Molecular Neurobiology, 2021)

Study on synthesis and anticancer activity of 17beta-estradiol-phenol/aniline nitrogen mustard derivatives - Yu-dong Yin; Jing-jing Liu; Wen-fei Liao; Xian-kun Guo; Li-shan Zhang; Wei-bin Mo; Ke-guang Cheng (Medicinal Chemistry Research, 2021)

RNA-seq analysis of ischemia stroke and normal brain in a tree shrew model with or without type 2 diabetes mellitus - Ling Zhao; Shiying Huang; Qiwei Liao; Xia Li; Shufen Tan; Shuqing Li; Tingyu Ke (Metabolic Brain Disease, 2021)

Study on the Influence of Close Distance Construction of Urban Tunnel on the Existing Station - Yang Zheng; Ke Wu; Jie Sun; Rong Chen; Yameng Li; Shifeng Yang (Geotechnical and Geological Engineering, 2021)

Design and Evaluation of Multiplex One-Step Reverse Transcription PCR–Dipstick Chromatography Method for the Analysis of Seven Respiratory Pathogens - Li Luo; Qianming Chen; Sheng Qin; Qiang Luo; Zhenjie Liu; Qiong Li; Shuilan Zheng; Xianzhang Huang; Peifeng Ke; Xiangsheng Yang; Hui Xiao; Ning Xu (Current Microbiology, 2021)

Deep profile soil moisture distribution characteristics for different micro-topographies on the semi-arid Loess Plateau, China - Qing-ping Gou; Qing-ke Zhu; Yi-xuan Li; Xiang-lei Tian; Peng-xiang Wang; Yun-ling Xin; Shu-yuan Luo (Journal of Mountain Science, 2021)

Correction to: Integrated study of circRNA, lncRNA, miRNA, and mRNA networks in mediating the effects of testicular heat exposure - Ke Hu; Chaofan He; Xunying Sun; Longhui Li; Yifan Xu; Kejia Zhang; Xiaohua Liu; Meng Liang (Cell and Tissue Research, 2021)