O-GlcNAc Transferase (OGT) Protects Cerebral Neurons from Death During Ischemia/Reperfusion (I/R) Injury by Modulating Drp1 in Mice - Jingru Zhao; Lipeng Dong; Tiantian Huo; Jinming Cheng; Xiaojuan Li; Xiaojuan Huangfu; Sujuan Sun; Hebo Wang; Litao Li (NeuroMolecular Medicine, 2022)

A New Dual-peak Fluorescent Probe for Water Content Detection Made From Taxus - Gang Wang; Yaping Li; Haipeng Chen; Shuqin Tang; Yiyang Cheng; Yuhong Yu; Abdul Qayoom Majeedano; Shangrao Pu; Gang Wang (Journal of Fluorescence, 2022)

Association of urinary or blood heavy metals and mortality from all causes, cardiovascular disease, and cancer in the general population: a systematic review and meta-analysis of cohort studies - Xianwei Guo; Wanying Su; Ning Li; Qiuxia Song; Hao Wang; Qiwei Liang; Yaru Li; Scott Lowe; Rachel Bentley; Zhen Zhou; Evelyn J. Song; Ce Cheng; et al. (Environmental Science and Pollution Research, 2022)

Association between ambient air pollution exposure during pregnancy and gestational diabetes mellitus: a meta-analysis of cohort studies - Xinyu Zhou; Changlian Li; Han Cheng; Junyi Xie; Feng Li; Lishan Wang; Rui Ding (Environmental Science and Pollution Research, 2022)

Effect of ambient O3 on mortality due to circulatory and respiratory diseases in a high latitude city of northeast China - Yifan Zhang; Yuxia Ma; Jiahui Shen; Heping Li; Hang Wang; Bowen Cheng; Liya Ma (Environmental Science and Pollution Research, 2022)

Two novel and efficient plant composites for the degradation of oxytetracycline: nanoscale ferrous sulphide supported on rape straw waste - Yan Yang; Xiaoxun Xu; Shirong Zhang; Guiyin Wang; Zhanbiao Yang; Zhang Cheng; Junren Xian; Ting Li; Yulin Pu; Wei Zhou; Gang Xiang (Environmental Science and Pollution Research, 2022)

Ensemble forecast of tropical cyclone tracks based on deep neural networks - Chong Wang; Qing Xu; Yongcun Cheng; Yi Pan; Hong Li (Frontiers of Earth Science, 2022)

Rhizobium quercicola sp. nov., isolated from the leaf of Quercus variablis in China - Cheng-Bin Wang; Dan-Ran Bian; Ning Jiang; Han Xue; Chun-Gen Piao; Yong Li (Archives of Microbiology, 2022)

Basin structure and multiresource potential based on high-precision airborne gravity and magnetic data - Yan-Xu Liu; Wen-Yong Li; An-Qi Cao; Shan Gao; Ning Wang; Li-Jie Wang; Cheng Yang (Applied Geophysics, 2022)

Food irradiation: a promising technology to produce hypoallergenic food with high quality - Xiaowen Pi; Yili Yang; Yuxue Sun; Xibo Wang; Yin Wan; Guiming Fu; Xin Li; Jianjun Cheng (Critical Reviews in Food Science and Nutrition, 2022)

Home Composting for Onsite Treatment of Household Organic Solid Waste: A Review - Jingwen Cheng; Rongrong Yin; Wenhai Luo; Yanming Li; Lingxiao Wang; Ruixue Chang (Current Pollution Reports, 2022)

Synthesis and in vitro biological evaluation of novel dendrocandin analogue as potential anti-tumor agent - Jing-Yun Yan; Hao-Nan Yang; Ning Yang; Yin-Rong Xie; Xiu-Li Sun; Ye-Wei Huang; Cheng-Ting Zi; Xuan-Jun Wang; Jun Sheng (Natural Product Research, 2022)

Nanoscale storage encryption: data storage in synthetic DNA using a cryptosystem with a neural network - Yue Teng; Shan Yang; Liyan Liu; Ruicun Liu; Yaofeng Chen; Jinyu Li; Qian Yang; Tuoyu Liu; Yujun Cui; Peng Cheng; Shengqi Wang (Science China Life Sciences, 2022)

BcWRKY1 confers salt sensitivity via inhibiting Reactive oxygen species scavenging - Shuilin Yuan; Die Hu; Yuan Wang; Cen Shao; Tongkun Liu; Changwei Zhang; Feng Cheng; Xilin Hou; Ying Li (Plant Molecular Biology, 2022)

Temporal and spatial accumulation of potentially toxic elements (PTEs) in stream sediments from a large lead–zinc mine concentration area of Baoshan, Southwest China - Li Zhang; Zheng Yang; Qiaolin Wang; Fei Guo; Yuntao Song; Wei Han; Min Peng; Fei Liu; Kuo Li; Hangxin Cheng (Journal of Soils and Sediments, 2022)

CRIF1 promotes the progression of non-small-cell lung cancer by SIRT3- mediated deacetylation of PYCR1 - Qi Wang; Zhuolin Xie; Chang Li; Chun Xu; Cheng Ding; Sheng Ju; Jun Chen; Zihan Cui; Chen Chen; Biao Gu; Tengteng Wei; Jun Zhao (Journal of Molecular Histology, 2022)

Modification effects of seasonal and temperature variation on the association between exposure to nitrogen dioxide and ischemic stroke onset in Shenzhen, China - Yuchen Tian; Ming Xiang; Ji Peng; Yanran Duan; Ying Wen; Suli Huang; Lei Li; Shuyuan Yu; Jinquan Cheng; Xia Zhang; Peng Wang (International Journal of Biometeorology, 2022)

Differential responses of polysaccharides and antioxidant enzymes in alleviating cadmium toxicity of tuber traditional Chinese medicinal materials - Li Yang; Yuchen Kang; Haibo Dai; Xiaoqin Wang; Mengdi Xie; Jiaxin Liu; Cheng Gao; Hui Sun; Tianqi Ao; Wenqing Chen (Environmental Science and Pollution Research, 2022)

The role of estrogen receptor β in fine particulate matter (PM2.5) organic extract-induced pulmonary inflammation in female and male mice - Huaqi Guo; Hengyi Yu; Yan Feng; Wei Cheng; Yan Li; Yan Wang (Environmental Science and Pollution Research, 2022)

Selection and identification of a specific peptide binding to ovarian cancer cells from a phage-displayed peptide library - Qian Gao; Lirong Chen; Chenshuang Jia; Yue Yuan; Xinyao Li; Zheng Lu; Yang Feng; Ruixia Zhao; Xuewei Zhao; Yiwen Wang; Sinan Cheng; Caixia Zhang; et al. (Biotechnology Letters, 2022)

Protective Effect of Nanoselenium on Renal Oxidative Damage Induced by Mercury in Laying Hens - Yan Ma; Binyao Cheng; Yumeng Li; Zhuosi Wang; Xiang Li; Ao Ren; Qiujue Wu; Doudou Zhu; Bingbing Ren (Biological Trace Element Research, 2022)

Spatio-temporal Evolution of the Agricultural Eco-efficiency Network and Its Multidimensional Proximity Analysis in China - Hongjiao Qu; Yajing Yin; Junli Li; Wenwen Xing; Weiyin Wang; Cheng Zhou; Yunhua Hang (Chinese Geographical Science, 2022)

Neuroparsin 1 (MrNP1) and Neuroparsin 2 (MrNP2) Are Involved in the Regulation of Vitellogenesis in the Shrimp Macrobrachium rosenbergii - Chun Mei Ao; Li Li Shi; Wei Wang; Cheng Gui Wang; Siuming F. Chan (Frontiers in Marine Science, 2022)
Neuroparsins (NP) are small-size cysteine-rich neuropeptides first discovered in insects. They are known to be involved in insect reproduction. In this study, we have cloned two neuroparsin cDNAs (i.e., MrNP1 and MrNP2) from the freshwater shrimp Macrobrachium rosenbergii . The two neuroparsins consist of 12 cysteines, which is characteristic of the neuroparsin family. These cysteines are arranged in identical relative positions that form 6-disulfide bonds. MrNP1 and MrNP2 are most similar to the corresponding neuroparsin counterparts of the shrimp Macrobrachium nipponense . Phylogenetic study results suggested that MrNP1 and MrNP2 are closely related to MnNP1 and MnNP3, respectively. Also, an additional MrNP gene similar to MnNP2 is expected to exist in M. rosenbergii. The MrNP1 expression level is the highest in the ovary, and MrNP2 expression is higher in the brain and heart of the females. In addition, during the ovary maturation cycle, MrNP1 expression in the hepatopancreas is highest in stage V; in the ovary it is variable. MrNP2 expression in the hepatopancreas and ovary is the highest in stage II and stage I, respectively. In vivo and in vitro bioassay experiment results indicate that MrNP1 and MrNP2 recombinant proteins can stimulate the expression of the MrVg gene. In contrast, silencing of MrNP1 and MrNP2 genes would suppress MrVg, VgR, and CyclinB gene expressions. The results indicate that the products of both genes can stimulate vitellogenesis by up-regulating the MrVg gene expression. Results from their difference in expression patterns indicate that they might have different regulatory roles in vitellogenin synthesis. Since gene silencing of either MrNP1 or MrNP2 affected the expression of the other NP, we have hypothesized that coordinated regulatory action between MrNP1 and MrNP2 may be necessary for the normal vitellogenesis in M. rosenbergii.

Reproductive Biology of Yellowfin Tuna (Thunnus albacares) in Tropical Western and Central Pacific Ocean - Xiaofei Shi; Jian Zhang; Xiao Wang; Yixi Wang; Cheng Li; Jiangao Shi (Fishes, 2022)
A total of 756 yellowfin tuna (Thunnus albacares) caught by a Chinese drifting longliner in the tropical western and central Pacific Ocean (WCPO) from May 2018 to March 2019 were investigated to describe the reproductive biology of the species. Generalized linear model and polytomous logistic regression for the ordinal response model were employed to assess the effects of biometric and spatiotemporal factors (such as individual fork length (FL), fishing depth, dissolved oxygen, and month) on the reproductive traits of yellowfin tuna. The results showed that FLs ranged from 87 to 163 cm, averaging 115.8 cm (SD = ±14.2) for females and 121.8 cm (SD = ±16.8) for males. The proportion of males in the sampled fish was 0.61 (SD = ±0.29), and larger males (>130 cm) were proportionally predominant. Analyses based on the monthly variation of the gonadosomatic index and monthly proportion of sexual maturity stages of the gonads showed that the main spawning period of yellowfin tuna lasts from September to December. In addition, the 50% first maturity FLs of males and females were 111.96 cm (SD = ±1.04) and 119.64 cm (SD = ±1.30), respectively. This study provides new information on the reproductive development of T. albacares in the tropical WCPO region. These reproductive parameters reduce uncertainty in current stock assessment models, which will ultimately assist the fishery in becoming sustainable for future generations.

Effects of 3,6-Dibromocarbazole on Soil Health—Based on Soil Enzymes and the Biolog-ECO Test - Zhongkun Du; Ji Zhang; Chao Cheng; Baihui Shi; Lusheng Zhu; Jun Wang; Jinhua Wang; Bing Li (Water, Air, & Soil Pollution, 2022)

Experimental Investigation of Decoupled Charge Effect on Rock Fragmentation by Blasting - Li Yuan Chi; Cheng Wang; Zong-Xian Zhang; Xuan Xu; Jun Yang (Rock Mechanics and Rock Engineering, 2022)

The sources risk assessment combined with APCS/MLR model for potentially toxic elements in farmland of a first-tier city, China - Ning Li; Yan Li; Genmei Wang; Huanchao Zhang; Xiangling Zhang; Jiale Wen; Xinyu Cheng (Environmental Science and Pollution Research, 2022)

The impacts of ambient relative humidity and temperature on supine position-related obstructive sleep apnea in adults - Wen-Te Liu; Yuan-Hung Wang; Li-Te Chang; Chih-Da Wu; Dean Wu; Cheng-Yu Tsai; Chen-Chen Lo; Kang Lo; Kian Fan Chung; Ta-Yuan Chang; Kai-Jen Chuang; Yueh-Lun Lee; et al. (Environmental Science and Pollution Research, 2022)

Short-term effect of sulfur dioxide (SO2) change on the risk of tuberculosis outpatient visits in 16 cities of Anhui Province, China: the first multi-city study to explore differences in occupational patients - Xin-Qiang Wang; Jia-Wen Zhao; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Ying-Qing Li; Xin Cheng; Zhen-Hua Li; Yi-Cheng Mao; Cheng-Yang Hu; Kai Huang; Kun Ding; et al. (Environmental Science and Pollution Research, 2022)

Controlled rocking pile foundation system with replaceable bar fuses for seismic resilience - Zhao Cheng; Shuai Li; Jingquan Wang (Earthquake Engineering and Engineering Vibration, 2022)

Whole-transcriptome sequencing identifies key mRNAs, miRNAs, lncRNAs, and circRNAs associated with unexplained recurrent pregnancy loss - Yan Wang; Qing Cheng; Zhengyi Xia; Ran Zhou; Yiming Li; Lulu Meng; Qing Xu; Jianxin Tan; Zhengfeng Xu (Cell and Tissue Research, 2022)

Simulation studies for the detection of water-bearing structures based on the mine-induced polarization method - Cheng Wang; Depin Han; Xueqian Li (Arabian Journal of Geosciences, 2022)

Molecular Cloning of Heat Shock Protein 60 (SpHSP60) from Schizothorax prenanti and the Gene Expressions of Four SpHSPs during Lipopolysaccharide (LPS) Infection - Jianlu Zhang; Jiqin Huang; Cheng Fang; Wanchun Li; Hu Zhao; Fei Kong; Han Zhang; Hongxing Zhang; Qijun Wang (Fishes, 2022)
Heat shock proteins (HSPs) play a key role in anti-stress and immune processes and are associated with autoimmune diseases. In order to explore the immunological role of HSPs from Schizothorax prenanti (S. prenanti), SpHSP60 was cloned for the first time in this study, and the gene expressions of SpHSP27, SpHSP60, SpHSP70 and SpHSP90 in the hepatopancreas, head kidney, hindgut and spleen were analyzed by quantitative real-time PCR (qPCR) after treatment with lipopolysaccharide (LPS). The open reading frame of the SpHSP60 gene (GenBank accession number ON245159) is 1728 bp. It encodes a protein of 575 amino acids. Its C-terminus is a highly conserved and repeated glycine sequence, which is an important cofactor in ATP binding. Compared with the control group, most of the SpHSPs were significantly upregulated in the tissues examined at 12 or 24 h after LPS challenge. The most abundant expression of SpHSP70 was found in the head kidney at 24 h after LPS injection, followed by SpHSP27 in the spleen at 24 h; both of these SpHSPs displayed strong expression under the LPS stresses, about 20–70 fold more than that of SpHSP60 and SpHSP90. The temporal expression patterns of the four SpHSP genes were different in the four tissues examined. Taken together, the results suggest that SpHSP27, SpHSP60, SpHSP70 and SpHSP90 participate in innate immunity stimulated by LPS, and the response intensity of the SpHSPs was organ-specific, indicating they could provide early warning information against bacterial infection. The findings in our study will contribute to better understanding the biological processes and important roles of SpHSPs involved in defending against pathogenic bacterial challenge.

Risk Evaluation of Navigation Environment Based on Dynamic Weight Model and Its Application - Shuzhe Chen; Lei Wu; Cheng Xie; Li Zhou; Rui Wang; Zhao Liu; Quanlong Zhu; Lianzhong Zhu (Journal of Marine Science and Engineering, 2022)
In order to scientifically and reasonably evaluate the safety risk of ship navigation, to and better solve the problems of the poor sensitivity of static evaluation and insufficient ability to grasp the overall dynamic situation, in this paper, representative safety evaluation indexes for ship navigation are screened and the initial weight of each index is confirmed in combination with the improved analytic hierarchy process (IAHP), in order to learn the changes of navigation environment and accident samples in the waters in the jurisdiction. Finally, the dynamic risk evaluation is carried out by constructing a dynamic weight evaluation model for the safety risk of the navigation environment based on the weight fusion of subjective and objective impact factors. The waters under the jurisdiction of Sanya, China were selected for the study, and the navigation risk of the waters in the jurisdiction was calculated by using the dynamic weight evaluation model based on navigation risk. The calculation results are highly consistent with the results based on the statistics of historical accidents and the analysis of the characteristics of the navigation environment in the jurisdiction. The navigation risk in this water area is the greatest from May to September every year. The dynamic weight evaluation model can not only overcome the subjective evaluation distortion in the traditional risk evaluation theory of navigation environment in practical applications, but can also provide a scientific theoretical basis for the dynamic evaluation and early warning of the risk of ship navigation environments through continuous sample learning.

Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities - Lu Luo; Jun Yang; Cheng Wang; Jie Wu; Yafang Li; Xu Zhang; Hui Li; Hui Zhang; Yumei Zhou; Aiping Lu; Shilin Chen (Science China Life Sciences, 2022)

Genetic dissection of heterotic loci associated with plant weight by Graded pool-seq in heading Chinese cabbage (Brassica rapa) - Lixin Yue; Rifei Sun; Guoliang Li; Feng Cheng; Limin Gao; Qinghua Wang; Shifan Zhang; Hui Zhang; Shujiang Zhang; Fei Li (Planta, 2022)

Structural variability in the bulk soil, rhizosphere, and root endophyte fungal communities of Themeda japonica plants under different grades of karst rocky desertification - Ming Tang; Jie Liu; Wenpeng Hou; Reed M. Stubbendieck; Han Xiong; Jie Jin; Jiyi Gong; Chen Cheng; Xiaoxin Tang; Yinglong Liu; Zhaofeng Li; Jianfeng Wang; et al. (Plant and Soil, 2022)

CircWHSC1 expedites cervical cancer progression via miR-532-3p/LTBP2 axis - Yan Li; Fandong Meng; Chengguang Sui; Yang Wang; Dali Cheng (Molecular and Cellular Biochemistry, 2022)

Sevoflurane inhibits the malignant phenotypes of glioma through regulating miR-146b-5p/NFIB axis - Haili Wang; Guofang Cheng; Lili Quan; Haibo Qu; Ailing Yang; Jiangge Ye; Yuanbo Feng; Xiaofang Li; Xiaoli Shi; Hua Pan (Metabolic Brain Disease, 2022)

Prediction of the sea buckthorn AQP gene structure and its spatiotemporal expression pattern under drought stress - Dan Zhang; Nanxiang Yang; Jiawei Dong; Cheng Wang; Qiangfeng Li; Rong Wang; Zhipeng Feng; Dejuan Xie; Guisheng Ye; Yuhua Ma (Journal of Plant Biochemistry and Biotechnology, 2022)

Prediction of disability-free survival in healthy older people - Johannes Tobias Neumann; Le T. P. Thao; Anne M. Murray; Emily Callander; Prudence R. Carr; Mark R. Nelson; Rory Wolfe; Robyn L. Woods; Christopher M. Reid; Raj C. Shah; Anne B. Newman; Jeff D. Williamson; et al. (GeroScience, 2022)
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disability-free survival outcome was defined as absence of dementia, persistent disability or death. Selection of potential predictors from amongst 25 biomedical, psychosocial and lifestyle variables including recognized geriatric risk factors, utilizing a machine-learning approach. Separate models were developed for men and women. The selected predictors were evaluated in a multivariable Cox proportional hazards model and validated internally by bootstrapping. We included 19,114 Australian and US participants aged ≥65 years (median 74 years, IQR 71.6–77.7). Common predictors of a worse prognosis in both sexes included higher age, lower Modified Mini-Mental State Examination score, lower gait speed, lower grip strength and abnormal (low or elevated) body mass index. Additional risk factors for men included current smoking, and abnormal eGFR. In women, diabetes and depression were additional predictors. The biased-corrected areas under the receiver operating characteristic curves for the final prognostic models at 5 years were 0.72 for men and 0.75 for women. Final models showed good calibration between the observed and predicted risks. We developed a prediction model in which age, cognitive function and gait speed were the strongest predictors of disability-free survival in healthy older people. Trial registration Clinicaltrials.gov (NCT01038583)

Localization of salt-tolerant QTL in rice germination stage under different salinity concentrations - Yanning Wang; Liping Chen; Guiting Song; Tao Huang; Guangliang Wu; Jingai Tan; Peng Wang; Qin Cheng; Caijing Li; Qi Zhong; Shiying Huang; Mengmeng Yang; et al. (Euphytica, 2022)

Preparation of formate-free PMA@MOF-808 catalysts for deep oxidative desulfurization of model fuels - Cheng Wang; Airong Li; Yuling Ma; Shenglan Qing (Environmental Science and Pollution Research, 2022)

Alterations of dynamic functional connectivity between visual and executive-control networks in schizophrenia - Weiliang Yang; Xuexin Xu; Chunxiang Wang; Yongying Cheng; Yan Li; Shuli Xu; Jie Li (Brain Imaging and Behavior, 2022)

Myd88 knockdown with RNA interference induces in vitro immune hyporesponsiveness in dendritic cells from rhesus monkeys - Qiuhong Wang; Dongyun Cun; Desong Xu; Liang Lin; Jian Jiao; Li Zhang; Cheng Xi; Wei Li; Peng Chen; Mingdao Hu (Immunogenetics, 2022)

Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells - Nan Huang; Yaxun Wei; Yi Cheng; Xiaolong Wang; Qi Wang; Dong Chen; Wenjing Li (Genes & Genomics, 2022)

Evaluation of the inhibitory effects of four different microecological preparations on Cladophora - Jian Liu; Yunfei Sun; Wenfeng Han; Jinghao Li; Shihui Wang; Zhigang Yang; Yongxu Cheng (Aquaculture International, 2022)

Comparison of different inversion methods of D-T2 two-dimensional nuclear magnetic resonance logging and applicability analysis - Cheng-Lin Li; Mao-Jin Tan; Ke-Wen Wang; Feng Zhou; Ying-Ming Liu; Hai-Tao Zhang; Li-Zhi Xiao (Applied Geophysics, 2022)

Dust particles transport during the rare strong sandstorm process in Northern China in early year 2021 - Xianmang Xu; Peiyu Zhao; Yanchao Yin; Wei Cheng; Jin Wang; Peichuang Li; Yusheng Liu; Juan Dai; Wenpeng Yuan (Air Quality, Atmosphere & Health, 2022)

Geographic distance, sedimentation, and substrate shape cryptic crustose coralline algal assemblages in the world’s largest subtropical intertidal algal reef - Shing Hei Zhan; Ling Chen; Chen‐Pan Liao; Wun‐Ruei Chang; Cheng‐Chin Li; Guang‐You Tang; Ching‐Yu Liou; Wei‐Lung Wang; Shih‐Wei Wang; Shao‐Lun Liu (Molecular Ecology, 2022)
Algal reefs, concreted by crustose coralline algae (CCA), are the main biotic reefs in temperate waters but rare in the subtropics and tropics. The world's largest known intertidal algal reef in the subtropics is the Taoyuan Algal Reef (TAR) located in the northwestern coast of Taiwan. The biodiversity and ecology of the TAR are scarcely explored, and now the reef is imperiled by industrialization. Here, we document cryptic species of CCA in Taiwan, particularly the TAR, by sequencing the psb A genes of over 1800 specimens collected across Taiwan. We also examine the ecological background of the TAR by surveying its benthic composition and measuring its environmental parameters. Our data reveal that the TAR harbours a high diversity of cryptic CCA species (27 molecular operational taxonomic units, or mOTUs), many of which are potentially new to science (18 mOTUs) and/or endemic to the TAR (9 mOTUs). Comparing the CCA species inventory of the TAR with the rest of Taiwan shows that the TAR represents a unique hotspot of CCA taxa in the waters of Taiwan. Our analyses show that variation in the CCA assemblages in the TAR is associated with geographic distance, sedimentation, and substrate type (for example, reef vs. hermit crab shell), suggesting that dispersal limitation and contemporary environmental selection shape the CCA assemblages in the TAR. The data from this study can inform the monitoring of human impacts on the health of the TAR and contribute to our understanding of the ecological processes underlying algal reef development.

Quinoline, with the active site of 8‐hydroxyl, efficiently inhibits Micropterus salmoides rhabdovirus (MSRV) infection in vitro and in vivo - Bo‐Yang Li; Fei Yang; Zhong‐Yu Zhang; Yu‐Feng Shen; Tao Wang; Liang Zhao; Jia‐Cheng Qin; Fei Ling; Gao‐Xue Wang (Journal of Fish Diseases, 2022)
Micropterus salmoides rhabdovirus (MSRV) is an significant pathogen that causes high mortality and related economic losses in bass aquaculture. There is no effective or approved therapy to date. In this study, we evaluated the anti‐MSRV effects of 22 quinoline derivatives in grass carp ovary (GCO) cells. Among these compounds, 8‐hydroxyquinoline exhibited valid inhibition in decreasing MSRV nucleoprotein gene expression levels of 99.3% with a half‐maximal inhibitory concentrations (IC 50 ) value of 4.66 μM at 48 h. Moreover, 8‐hydroxyquinoline significantly enhanced a protective effect in GCO cells by reducing the cytopathic effect (CPE). By comparing the anti‐MSRV activity of 22 quinoline derivatives, we found that 8‐hydroxyquinoline possessed the efficient active site of 8‐hydroxyl and inhibited MSRV infection in vitro. For in vivo studies, 8‐hydroxyquinoline via intraperitoneal injection exhibited an antiviral effect in MSRV‐infected largemouth bass by substantially enhancing the survival rate by 15.0%. Importantly, the viral loads in the infected largemouth bass notably reduced in the spleen on the third days post‐infection. Overall, 8‐hydroxyquinoline was considered to be an efficient agent against MSRV in aquaculture.

Volcanic rocks of the Elashan Formation in the Dulan-Xiangride Basin, East Kunlun Orogenic Belt, NW China: Petrogenesis and implications for Late Triassic geodynamic evolution - Xingzhu Fan; Fengyue Sun; Chenghan Xu; Dongqian Wu; Lu Yu; Li Wang; Cheng Yan; Shahzad Bakht (International Geology Review, 2022)

Fishery Resources, Ecological Environment Carrying Capacity Evaluation and Coupling Coordination Analysis: The Case of the Dachen Islands, East China Sea - Hong Huang; Zuanyi Wang; Yingdong Li; Xu Zhao; Zhenhua Wang; Xiaopeng Cheng (Frontiers in Marine Science, 2022)
Impacts of human activity on the sustainable development of marine fisheries have been greatly concerned, and the carrying capacity with theoretic and practical meanings has become a focused area over the past two decades. More importantly, there are few studies on the fishery resources and environment compound system. In this study, based on the investigation data in Dachen Islands during 2019–2021, we proposed the evaluation method of fishery resources and ecological environment carrying capacity (FRCC & MEECC) and analyzed the coupling coordination degree between the fishery resources and environment. The results showed that (1) the MEECC of Dachen Islands was in the critical overload state and fluctuated significantly among seasons and the winter voyage of 2021 was the worst. (2) The nekton index of Dachen Islands was basically stable, the fish eggs and juvenile index dropped markedly, and the FRCC was also critically overloaded. (3) The fishery resources and marine environment were moderately balanced. Further, the development was relatively synchronized in autumn of 2019 and 2020, while the fishery resources in spring of 2021 lagged behind the marine environment.

A new highly oxygenated germacranolide from Carpesium nepalense var. lanatum (C.B.Clarke) Kitam - Yi-Fan Yu; Yue-Qian Li; Ru-Yue Wang; Xu Liu; Wen-Bo Cui; Xiao-Han Chen; Cheng-Mu Zhao; Feng-Ming Qi; Zhan-Xin Zhang; Dong-Qing Fei (Natural Product Research, 2022)

Secoiridoid glycosides from the fruits of Cornus officinalis - Xin Wang; Xiang-Jian Zhong; Na Zhou; Lin-Lin Ji; Jin-Jie Li; Ning Cai; Qing-Bo Wang; Peng-Cheng Lin; Xiao-Ya Shang (Natural Product Research, 2022)

Exogenous artificial DNA forms chromatin structure with active transcription in yeast - Jianting Zhou; Chao Zhang; Ran Wei; Mingzhe Han; Songduo Wang; Kaiguang Yang; Lihua Zhang; Weigang Chen; Mingzhang Wen; Cheng Li; Wei Tao; Ying-Jin Yuan (Science China Life Sciences, 2022)
Yeast artificial chromosomes (YACs) are important tools for sequencing, gene cloning, and transferring large quantities of genetic information. However, the structure and activity of YAC chromatin, as well as the unintended impacts of introducing foreign DNA sequences on DNA-associated biochemical events, have not been widely explored. Here, we showed that abundant genetic elements like TATA box and transcription factor-binding motifs occurred unintentionally in a previously reported data-carrying chromosome (dChr). In addition, we used state-of-the-art sequencing technologies to comprehensively profile the genetic, epigenetic, transcriptional, and proteomic characteristics of the exogenous dChr. We found that the data-carrying DNA formed active chromatin with high chromatin accessibility and H3K4 tri-methylation levels. The dChr also displayed highly pervasive transcriptional ability and transcribed hundreds of noncoding RNAs. The results demonstrated that exogenous artificial chromosomes formed chromatin structures and did not remain as naked or loose plasmids. A better understanding of the YAC chromatin nature will improve our ability to design better data-storage chromosomes.

Multiple indeterminate domain (IDD)–DELLA1 complexes participate in gibberellin feedback regulation in peach - Yajun Jiang; Jiajia Chen; Xianbo Zheng; Bin Tan; Xia Ye; Wei Wang; Langlang Zhang; Jidong Li; Zhiqian Li; Jun Cheng; Jiancan Feng (Plant Molecular Biology, 2022)

Investigation on the characteristics of gut microbiota in critically endangered blue-crowned laughingthrush (Garrulax courtoisi) - Cong Wang; Jiawei Li; Yuwei Cheng; Hongbo Tang; Yanpeng Xiong; Yongfei Wu; Luping Wang; Daoqiang Liu; Jianhua Huang (Molecular Genetics and Genomics, 2022)

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight - Yu-Qian Song; Shi-Di Hu; Xu Lin; Xiang-He Meng; Xiao Wang; Yin-Hua Zhang; Cheng Peng; Rui Gong; Tao Xu; Tong Zhang; Chen-Zhong Li; Dao-Yan Pan; et al. (Journal of Molecular Medicine, 2022)
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibility variants shared between these two traits. We detected 5 novel potential pleiotropic loci which are located at or near 7 different genes ( NTAN1 , PDXDC1 , CACNA1G , JAG1 , FAT1P1 , CCDC170 , ESR1 ), among which PDXDC1 and FAT1P1 have not previously been linked to these phenotypes. To partially validate the findings, we demonstrated that the expression of PDXDC1 was dramatically reduced in ovariectomized (OVX) mice in comparison with sham-operated (SHAM) mice in both the growth plate and trabecula bone. Furthermore, immunohistochemistry assay with serial sections showed that both osteoclasts and osteoblasts express PDXDC1 , supporting its potential role in bone metabolism. In conclusion, our study provides insights into some shared genetic mechanisms for BMD and BW as well as a novel potential therapeutic target for the prevention of OP in the early stages of the disease development. Key messages We investigated pleiotropy-informed enrichment between LS BMD and BW. We identified genetic variants related to both LS BMD and BW by utilizing a cFDR approach. PDXDC1 is a novel pleiotropic gene which may be related to both LS BMD and BW. Elevated expression of PDXDC1 is related to higher BMD and lower ratio n-6/n-3 PUFA indicating a bone protective effect of PDXDC1.

Novel ratiometric fluorescent probe based on internal reference and its detection of hydrazine - Xiaohong Cheng; Shuang Li; Mengyun Gong; Song Wang; Wangnan Li (Journal of Fluorescence, 2022)

Health risk of extreme low temperature on respiratory diseases in western China - Yuxia Ma; Hang Wang; Bowen Cheng; Jiahui Shen; Heping Li; Yongtao Guo; Yifan Cheng (Environmental Science and Pollution Research, 2022)

Novel combination of bioleaching and persulfate for the removal of heavy metals from metallurgical industry sludge - Chen Chen; Huidong Li; Fengjiao Cui; Zhixia Wang; Xinxin Liu; Gang Jiang; Tianjia Cheng; Runying Bai; Lei Song (Environmental Science and Pollution Research, 2022)

Comprehensive investigation of water-conducting channels in near-sea limestone mines using microtremor survey, electrical resistivity tomography, and tracer tests: a case study in Beihai City, China - Maoxin Su; Kai Cheng; Haiyan Li; Yiguo Xue; Peng Wang; Xiaoyin Ma; Congcong Li (Bulletin of Engineering Geology and the Environment, 2022)

Alternative Splicing of the Lobster (Homarus americanus) Crustacean Hyperglycemic Hormone A and B Genes Produce 2 Protein Variants Involved in Vitellogenin Inhibition - Cheng Gui Wang; Wei Wang; Li Li Shi; Yu Chun Shen; Siuming F. Chan (Frontiers in Marine Science, 2022)
Current BLASTP search analysis results suggested that the lobster ( Homarus americanus ) HaCHH-A and HaCHH-B may be derived from two different four-exon genes. Repeated tissue expression studies have revealed much different expression patterns of these two genes from those reported in the past. With RT-PCR, rapid amplification of complementary DNA (cDNA) ends (RACE), and genomic DNA cloning, we confirmed that the HaCHH-A and HaCHH-B transcripts were derived from two different four-exon CHH genes. By an alternative splicing mechanism, each gene can produce different but larger transcript variants (i.e., sHaCHH-A and sHaCHH-B ) mainly in different non-eyestalk tissues of the females. The larger and unspliced transcripts can be detected in the hepatopancreas, gill, heart, nerve cord, brain, ovary, and thoracic ganglion of the reproductive females. The expression patterns of sHaCHH-A and sHaCHH-B in other non-eyestalk tissues suggest that these transcripts have a wide spectrum of expressions during the female reproductive cycle. An in vitro organ explant culture system was developed to investigate the reproductive function of these cDNAs. The results showed that the recombinant proteins for sHaCHH-A and sHaCHH-B inhibited the gene expression of vitellogenin, whereas the double-stranded RNA (dsRNA) for sHaCHH-A and sHaCHH-B stimulated the expression of the vitellogenin gene in vitro . The results of the study may provide insights for the development of techniques to induce gonad development without using eyestalk ablation operation. This is the first in-depth report of the characterization of two four-exon CHH genes in a crustacean.

Chrysomutanin and related meroterpenoids from a DES mutant of the marine-derived fungus Penicillium chrysogenum S-3-25 - Hua Qiao; Shu-Hua Zhang; Yuan Dong; Yu Yang; Rui Xu; Bo Chen; Yi Wang; Tian-Jiao Zhu; Cheng-Bin Cui; Guo-Gang Zhang; Chang-Wei Li (Natural Product Research, 2022)

Prenatal Isoflurane Exposure Induces Developmental Neurotoxicity in Rats: the Role of Gut Microbiota - Li-Kuan Wang; Xu-Dong Yang; Dan Zhou; Tong Cheng; Xiang Zhang; Hai-Yin Wu (Neurotoxicity Research, 2022)

Paeoniflorin ameliorates cognitive impairment in Parkinson’s disease via JNK/p53 signaling - Zhu-qing He; Peng-fei Huan; Li Wang; Jian-cheng He (Metabolic Brain Disease, 2022)
Paeoniflorin (PF) has numerous benefits, including anti-inflammatory and anti-apoptosis effects. However, it is not clear if it has neuroprotective effects against cognitive impairment (CI) in Parkinson’s disease (PD). Through network pharmacology, we identified probable targets as well as signal pathways through which PF might affect CI in PD. Then, we experimentally validated our findings. The core genes of the protein-protein interactions (PPI) network include MAPK8 (JNK), TP53, CASP3 (caspase-3), postsynaptic density protein-95 (PSD-95) and synaptophysin (SYN). Pathway enrichment analysis revealed that genes involved in apoptosis and mitogen-activated protein kinase (MAPK) signaling were significantly enriched. Because JNK is a key mediator of p53-induced apoptosis, we wondered if JNK/p53 pathway influences the effects of PF against apoptosis in mouse model of PD. Molecular docking analysis showed that PF had good affinity for JNK/p53. The results of the experiments indicated that PF ameliorated behavioral impairments and upregulated the expression of the dopamine (DA) neurons, suppressed cell apoptosis in substantia nigra pars compacta (SNpc) of PD. Additionally, PF improved 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neuronal injury by inhibiting apoptosis in hippocampal neurons of the CA1 and CA3, and upregulating PSD-95 as well as SYN protein levels. Similar protective effects were observed upon JNK/p53 pathway inhibition using SP600125. Overall, PF improved CI in PD by inhibiting JNK/p53 pathway.

Numerical study of the runout behavior of the Kamenziwan landslide in the Three Gorges Reservoir region, China - Bing Li; Huiming Tang; Wenping Gong; Zhan Cheng; Tianzheng Li; Lei Wang (Landslides, 2022)

Regulation of endothelial progenitor cell functions during hyperglycemia: new therapeutic targets in diabetic wound healing - Gui Wan; Yangyang Chen; Jing Chen; Chengqi Yan; Cheng Wang; Wenqing Li; Renqun Mao; Hans-Günther Machens; Xiaofan Yang; Zhenbing Chen (Journal of Molecular Medicine, 2022)

Functional characterization of CD49f+ hepatic stem/progenitor cells in adult mice liver - Ziqi Guo; Shiming Pu; Yun Li; Xiaoxia Wang; Suying Hu; Hongxia Zhao; Cheng Yang; Zuping Zhou (Journal of Molecular Histology, 2022)

DVPred: a disease-specific prediction tool for variant pathogenicity classification for hearing loss - Fengxiao Bu; Mingjun Zhong; Qinyi Chen; Yumei Wang; Xia Zhao; Qian Zhang; Xiarong Li; Kevin T. Booth; Hela Azaiez; Yu Lu; Jing Cheng; Richard J. H. Smith; et al. (Human Genetics, 2022)

Short-term effect of ambient air pollutant change on the risk of tuberculosis outpatient visits: a time-series study in Fuyang, China - Xin-Qiang Wang; Ying-Qing Li; Cheng-Yang Hu; Kai Huang; Kun Ding; Xiao-Jing Yang; Xin Cheng; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Yong-Zhong Zhang; Zhen-tao Ding; et al. (Environmental Science and Pollution Research, 2022)

Monitoring soil salinization and its spatiotemporal variation at different depths across the Yellow River Delta based on remote sensing data with multi-parameter optimization - Tiantian Cheng; Jiahua Zhang; Sha Zhang; Yun Bai; Jingwen Wang; Shuaishuai Li; Tehseen Javid; Xianglei Meng; Til Prasad Pangali Sharma (Environmental Science and Pollution Research, 2022)

Influence of the NAO on Wintertime Surface Air Temperature over East Asia: Multidecadal Variability and Decadal Prediction - Jianping Li; Tiejun Xie; Xinxin Tang; Hao Wang; Cheng Sun; Juan Feng; Fei Zheng; Ruiqiang Ding (Advances in Atmospheric Sciences, 2022)
In this paper, we investigate the influence of the winter NAO on the multidecadal variability of winter East Asian surface air temperature (EASAT) and EASAT decadal prediction. The observational analysis shows that the winter EASAT and East Asian minimum SAT (EAmSAT) display strong in-phase fluctuations and a significant 60–80-year multidecadal variability, apart from a long-term warming trend. The winter EASAT experienced a decreasing trend in the last two decades, which is consistent with the occurrence of extremely cold events in East Asia winters in recent years. The winter NAO leads the detrended winter EASAT by 12–18 years with the greatest significant positive correlation at the lead time of 15 years. Further analysis shows that ENSO may affect winter EASAT interannual variability, but does not affect the robust lead relationship between the winter NAO and EASAT. We present the coupled oceanic-atmospheric bridge (COAB) mechanism of the NAO influences on winter EASAT multidecadal variability through its accumulated delayed effect of ∼15 years on the Atlantic Multidecadal Oscillation (AMO) and Africa–Asia multidecadal teleconnection (AAMT) pattern. An NAO-based linear model for predicting winter decadal EASAT is constructed on the principle of the COAB mechanism, with good hindcast performance. The winter EASAT for 2020–34 is predicted to keep on fluctuating downward until ∼2025, implying a high probability of occurrence of extremely cold events in coming winters in East Asia, followed by a sudden turn towards sharp warming. The predicted 2020/21 winter EASAT is almost the same as the 2019/20 winter.

First report of acanthocephalan parasite, Longicollum pagrosomi Yamaguti, 1935 in cultured red snapper ( Lutjanus erythropterus ) in Taiwan - Li‐Wu Cheng; Shreesha Rao; Pei‐Chi Wang; Shih‐Chu Chen (Journal of Fish Diseases, 2022)
For the first time, Longicollum pagrosomi Yamaguti, 1935, an acanthocephalan parasite, has been characterized with morphological, histopathological and molecular detail in farmed red snapper ( Lutjanus erythropterus ) in Taiwan. The diseased fish showed clinical signs of anorexia, emaciation and were gasping for air at the water's surface. Gross examination revealed extensive necrosis in the intestine and even penetration at the site of parasitic attachment, resulting in a large number of parasites being lodged in the peritoneal cavity, surrounded by black hyperplastic connective tissue. The parasites collected from the intestine were studied using optical microscopy, histopathology, scanning electron microscopy (SEM) and molecular phylogenetic analysis. They were creamy white in colour, and were separated into their proboscis, neck and metasoma (trunk) under optical microscopy. Histopathological examination revealed ovarian balls (floating ovaries) inside the ligament sac and eggs within the egg sorting apparatus. The SEM images revealed that the proboscis had 11–14 longitudinal rows with 9–12 recurrent, backward‐facing, organized hooks. In the 18S and 28S phylogenetic tree, sequences of the specimens were identical to those of other Longicollum pagrosomi , in addition to the morphological features. Thus, we confirmed that the parasites belonged to Longicollum pagrosomi in this study.

Global divergent trends of algal blooms detected by satellite during 1982–2018 - Chong Fang; Kaishan Song; Hans W Paerl; Pierre‐Andre Jacinthe; Zhidan Wen; Ge Liu; Hui Tao; Xiaofeng Xu; Tiit Kutser; Zongming Wang; Hongtao Duan; Kun Shi; et al. (Global Change Biology, 2022)
Algal blooms (ABs) in inland lakes have caused adverse ecological effects, and health impairment of animals and humans. We used archived Landsat images to examine ABs in lakes (>1 km 2 ) around the globe over a 37‐year time span (1982–2018). Out of the 176032 lakes with area >1 km 2 detected globally, 863 were impacted by ABs, 708 had sufficiently long records to define a trend, and 66% exhibited increasing trends in frequency ratio (FRQR, ratio of the number of ABs events observed in a year in a given lake to the number of available Landsat images for that lake) or area ratio (AR, ratio of annual maximum area covered by ABs observed in a lake to the surface area of that lake), while 34% showed a decreasing trend. Across North America, an intensification of ABs severity was observed for FRQR ( p p p p

Expansion of bilin‐based red light sensors in the subaerial desert cyanobacterium Nostoc flagelliforme - Hai‐Feng Xu; Guo‐Zheng Dai; Yu‐Jie Wang; Chao Cheng; Jin‐Long Shang; Ren‐Han Li; Ke Liu; Deqiang Duanmu; Bao‐Sheng Qiu (Environmental Microbiology, 2022)
Summary Light is the crucial environmental signal for desiccation‐tolerant cyanobacteria to activate photosynthesis and prepare for desiccation at dawn. However, the photobiological characteristics of desert cyanobacteria adaptation to one of the harshest habitats on Earth remain unresolved. In this study, we surveyed the genome of a subaerial desert cyanobacterium Nostoc flagelliforme and identified two phytochromes and seven cyanobacteriochromes (CBCRs) with one or more bilin‐binding GAF (cGMP phosphodiesterase/adenylyl cyclase/FhlA) domains. Biochemical and spectroscopic analyses of 69 purified GAF‐containing proteins from recombinant phycocyanobilin (PCB), biliverdin or phycoerythrobilin‐producing Escherichia coli indicated that nine of these proteins bind chromophores. Further investigation revealed that 11 GAFs form covalent adducts responsive to near‐UV and visible light: eight GAFs contained PCB chromophores, three GAFs contained biliverdin chromophores and one contained the PCB isomer, phycoviolobilin. Interestingly, COO91_03972 is the first‐ever reported GAF‐only CBCR capable of sensing five wavelengths of light. Bioinformatics and biochemical analyses revealed that residue P132 of COO91_03972 is essential for chromophore binding to dual‐cysteine CBCRs. Furthermore, the complement of N . flagelliforme CBCRs is enriched in red light sensors. We hypothesize that these sensors are critical for the acclimatization of N . flagelliforme to weak light environments at dawn.

Knockout of GGPPS1 restrains rab37-mediated autophagy in response to ventilator-induced lung injury - Zexu Wang; Meizi Chen; Xia Pan; Li Wang; Cheng Yin; Qiuqi Lin; Jingjing Jiang; Yunlei Zhang; Bing Wan (Human Cell, 2022)

Petrogenesis and tectonic setting of the early-middle triassic subduction-related granite in the eastern segment of East Kunlun: evidences from petrology, geochemistry, and zircon U-Pb-Hf isotopes - Zuo-Chen Li; Xian-Zhi Pei; Paul D. Bons; Rui-Bao Li; Lei Pei; Guo-Chao Chen; You-Xin Chen; Cheng-Jun Liu; Meng Wang; Shao-Wei Zhao; Xiao-Bing Li; Feng Gao (International Geology Review, 2022)

Predicting gas content in coalbed methane reservoirs using seismic waveform indication inversion: a case study from the Upper Carboniferous Benxi Formation, eastern Ordos Basin, China - Jiabei Wang; Zhijun Li; Cen Chen; Cheng Meng (Acta Geophysica, 2022)

Genome-wide Identification and Characteristics Analysis of Melon (Cucumis melo L.) MYB Transcription Factors and Their Responses to Autotoxicity and Saline-alkali Stress - Yifang Zhang; Ziyan Xie; Fangyan Wang; Cheng Zhong; Yumo Liu; Zhiying Li; Gefu Wang-Pruski; Zhizhong Zhang (Tropical Plant Biology, 2022)

Extensive sequence divergence between the reference genomes of Taraxacum kok-saghyz and Taraxacum mongolicum - Tao Lin; Xia Xu; Huilong Du; Xiuli Fan; Qingwen Chen; Chunyan Hai; Zijian Zhou; Xiao Su; Liquan Kou; Qiang Gao; Lingwei Deng; Jinsheng Jiang; et al. (Science China Life Sciences, 2022)

Characterization of Photorhabdus Virulence Cassette as a causative agent in the emerging pathogen Photorhabdus asymbiotica - Xia Wang; Jiaxuan Cheng; Jiawei Shen; Liguo Liu; Ningning Li; Ning Gao; Feng Jiang; Qi Jin (Science China Life Sciences, 2022)

Apelin-13 attenuates early brain injury through inhibiting inflammation and apoptosis in rats after experimental subarachnoid hemorrhage - Xiaoyan Shen; Guiqiang Yuan; Bing Li; Cheng Cao; Demao Cao; Jiang Wu; Xiang Li; Haiying Li; Haitao Shen; Zhong Wang; Gang Chen (Molecular Biology Reports, 2022)

CAV1 is a prognostic predictor for patients with idiopathic pulmonary fibrosis and lung cancer - Dongdong Yin; Jiayang Qiu; Suxia Hu; Longqiang Cheng; Hui Li; Xingpu Cheng; Shun Wang; Jun Lu (Journal of Biosciences, 2022)

Optimal coupling combinations between dripper discharge and irrigation interval of maize for seed production under plastic film-mulched drip irrigation in an arid region - Shimeng Ma; Ling Tong; Shaozhong Kang; Sufen Wang; Xuanyi Wu; Xiaona Cheng; Qiangqiang Li (Irrigation Science, 2022)

Discovery of a Natural Product with Potent Efficacy Against SARS-CoV-2 by Drug Screening - Daixi Li; Cheng Wang; Shaobo Wang; Aamir Mehmood; Jiang Gu; Xin Cheng; Peiqin Chen; JingFei Qiu; Jinghong Zhao; Junping Wang; Dongqing Wei (Interdisciplinary Sciences: Computational Life Sciences, 2022)

Circular RNA circ_0008934 promotes hepatocellular carcinoma growth and metastasis through modulating miR-1305/TMTC3 axis - Jia-Xi Li; Jin-Jiang Wang; Zhou-Feng Deng; Hao Zheng; Chun-Mei Yang; Ying Yuan; Cheng Yang; Fang-Fang Gu; Wei-Qi Wu; Guang-Lei Qiao; Li-Jun Ma (Human Cell, 2022)

Suitable chemical fertilizer reduction mitigates the water footprint of maize production: evidence from Northeast China - Jianqin Wang; Lijie Qin; Jingru Cheng; Chenchen Shang; Bo Li; Yongcai Dang; Hongshi He (Environmental Science and Pollution Research, 2022)

Spatial Spillover Effects of Renewable Energy on Carbon Emissions in Less-developed Areas of China - Jun Bai; Shixiang Li; Qiying Kang; Nan Wang; Kailu Guo; Jinfeng Wang; Jinhua Cheng (Environmental Science and Pollution Research, 2022)

Engineering application of fuzzy evaluation based on comprehensive weight in the selection of geophysical prospecting methods - Maoxin Su; Congcong Li; Yiguo Xue; Peng Wang; Kai Cheng; Yimin Liu (Earth Science Informatics, 2022)

Load transfer laws of tensile anchors in rock masses with weak interlayers based on a shear-slipping updating model - Yan Wang; Xin Xiang; Chang-dong Li; Guo-qiang Zhu; Cheng-bin Song; Jin-ye Xian; Jia-jun Zhang (Journal of Mountain Science, 2022)

Demersal fish diversity and molecular taxonomy in the Bering Sea and Chukchi Sea - Hai Li; Fang Yang; Xuehua Wang; Yuan Li; Nan Zhang; Ran Zhang; Cheng Liu; Hushun Zhang; Longshan Lin; Puqing Song (Conservation Genetics Resources, 2022)

Characterization and genomic analysis of a Demerecviridae phage SP76 with lytic multiple-serotypes of Salmonella - Hui Wang; Yun Shen; Pei LI; Yuyi Xiao; Yanxiu Li; Xiapei Hu; Zhuohao Wang; Zile Cheng; Zitong Wang; Qingxin Liu; Si Qin; Xiang Huo; et al. (Archives of Microbiology, 2022)

Haloterrigena gelatinilytica sp. nov., a new extremely halophilic archaeon isolated from salt-lake - Bing-Bing Liu; Nimaichand Salam; Manik Prabhu Narsing Rao; Shuang Cheng; Yuan-Guo Xie; Lai-You Wang; Yuan-ru Zhang; Xin-Yuan Yu; Shu-xian Guo; Wen-Jun Li (Archives of Microbiology, 2022)

Another Record: Ocean Warming Continues through 2021 despite La Niña Conditions - Lijing Cheng; John Abraham; Kevin E. Trenberth; John Fasullo; Tim Boyer; Michael E. Mann; Jiang Zhu; Fan Wang; Ricardo Locarnini; Yuanlong Li; Bin Zhang; Zhetao Tan; et al. (Advances in Atmospheric Sciences, 2022)
The increased concentration of greenhouse gases in the atmosphere from human activities traps heat within the climate system and increases ocean heat content (OHC). Here, we provide the first analysis of recent OHC changes through 2021 from two international groups. The world ocean, in 2021, was the hottest ever recorded by humans, and the 2021 annual OHC value is even higher than last year’s record value by 14 ± 11 ZJ (1 zetta J = 10 21 J) using the IAP/CAS dataset and by 16 ± 10 ZJ using NCEI/NOAA dataset. The long-term ocean warming is larger in the Atlantic and Southern Oceans than in other regions and is mainly attributed, via climate model simulations, to an increase in anthropogenic greenhouse gas concentrations. The year-to-year variation of OHC is primarily tied to the El Niño-Southern Oscillation (ENSO). In the seven maritime domains of the Indian, Tropical Atlantic, North Atlantic, Northwest Pacific, North Pacific, Southern oceans, and the Mediterranean Sea, robust warming is observed but with distinct inter-annual to decadal variability. Four out of seven domains showed record-high heat content in 2021. The anomalous global and regional ocean warming established in this study should be incorporated into climate risk assessments, adaptation, and mitigation.

MoOpy2 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae - Ying‐Ying Cai; Jing‐Yi Wang; Xi‐Yu Wu; Shuang Liang; Xue‐Ming Zhu; Lin Li; Jian‐Ping Lu; Xiao‐Hong Liu; Fu‐Cheng Lin (Environmental Microbiology, 2022)
Summary The development and pathogenicity of the fungus Magnaporthe oryzae , the causal agent of destructive rice blast disease, require it to perceive external environmental signals. Opy2, an overproduction‐induced pheromone‐resistant protein 2, is a crucial protein for sensing external signals in Saccharomyces cerevisiae . However, the biological functions of the homologue of Opy2 in M. oryzae are unclear. In this study, we identified that MoOPY2 is involved in fungal development, pathogenicity, and autophagy in M. oryzae . Deletion of MoOPY2 resulted in pleiotropic defects in hyphal growth, conidiation, germ tube extension, appressorium formation, appressorium turgor generation, and invasive growth, therefore leading to attenuated pathogenicity. Furthermore, MoOpy2 participates in the Osm1 MAPK pathway and the Mps1 MAPK pathway by interacting with the adaptor protein Mst50. The interaction sites of Mst50 and MoOpy2 colocalized with the autophagic marker protein MoAtg8 in the preautophagosomal structure sites (PAS). Notably, the Δ Moopy2 mutant caused cumulative MoAtg8 lipidation and rapid GFP‐MoAtg8 degradation in response to nitrogen starvation, showing that MoOpy2 is involved in the negative regulation of autophagy activity. Taken together, our study revealed that MoOpy2 of M. oryzae plays an essential role in the orchestration of fungal development, appressorium penetration, autophagy and pathogenesis.

Single-stranded RNA viruses activate and hijack host apical DNA damage response kinases for efficient viral replication - Pengcheng Li; Chenchen Xu; Xiaoyan Zhang; Cheng Cao; Xuejuan Wang; Gang Cai (Genome Instability & Disease, 2022)
The ataxia-telangiectasia mutated (ATM) and ATM-Rad3-related (ATR) are apical kinases that orchestrate the multifaceted DNA damage response (DDR) to a variety of genotoxic insults and regulate genomic stability. Whether RNA virus also manipulates the host’s DDR machine to facilitate replication is largely unknown. In this study, we revealed that single-stranded RNA virus replication specifically elicits host ATM- and ATR-mediated pathway activation and boosts their expression. The activated ATM and ATR are hijacked to the virus replication factory in the cytoplasm and facilitate viral gene expression and replication. Specific inhibitors targeting ATM and ATR strikingly block the viral proliferation and replication and inhibit expression of virus proteins. Our results reveal a novel, or otherwise noncanonical, conserved function of ATM/ATR outside DDR in promoting the replication of single-stranded RNA virus and provide an important mechanism of host–pathogen interactions.

Ecdysis Triggering Hormone, Eclosion Hormone, and Crustacean Cardioactive Peptide Play Essential but Different Roles in the Molting Process of Mud Crab, Scylla paramamosain - Yan-Fei Zhao; Qi-Qiao Wen; Chun-Mei Ao; Wei Wang; Li-Li Shi; Cheng-Gui Wang; Siuming-Francis Chan (Frontiers in Marine Science, 2022)
Molting behavior in insects is controlled by the ecdysis triggering hormone (ETH), eclosion hormone (EH) and the crustacean cardioactive peptide (CCAP). At present, the regulation of molting behavior in crustaceans remains unclear. Here, we studied the roles of ETH , EH , and CCAP in the molt regulation of the crab, Scylla paramamosain from their expression pattern and in vivo assays. The results showed that transcripts of ETH , EH , and CCAP were mainly localized in thoracic ganglia and fluctuated periodically with the molting cycle. When ETH or CCAP was knockdown at early premolt stage (D0), molting of crabs was interrupted and all animals died at late premolt stage (D2). While the EH gene was knock-down, most crabs were dead before D2. Injection of synthetic peptide for ETH or CCAP rescued ETH - or CCAP -gene knock-down crabs separately. However, none of peptides could rescue dsEH -injected crabs. At D0 stage, knockdown of ETH down-regulated the transcriptions of EH and CCAP ; while ETH was up-regulated when EH was knockdown. At D2 stage, ETH transcripts levels were reduced with the injection of dsEH but increased with the same dose of dsETH as crabs at D0 stage. Co-injection of ds ETH and ds EH down-regulated ETH at D2 stage. Results showed that ETH , EH , and CCAP play essential but different roles in molt regulation in mud crab. In summary, the result of this study contributes to the discovery of different molecular mechanisms between Insecta and Crustacea and may provide insight to develop fishery drugs that helps aquacultured crustaceans to molt successfully.

The antioxidant activities of flavonoids in Jerusalem artichoke ( Helianthus tuberosus L.) leaves and their quantitative analysis - Ming-Yang Wang; Zhi-Li Ma; Cheng-Li He; Xiao-Yan Yuan (Natural Product Research, 2022)

Prevalence and molecular epidemiology of equine piroplasmosis in China: a neglected tick-borne disease - Kewei Chen; Zhe Hu; Jingkun Li; Jingfei Wang; Diqiu Liu; Ting Qi; Wei Guo; Cheng Du; Xiaojun Wang (Science China Life Sciences, 2022)

Cancer metabolism and tumor microenvironment: fostering each other? - Yiyuan Yuan; Huimin Li; Wang Pu; Leilei Chen; Dong Guo; Hongfei Jiang; Bo He; Siyuan Qin; Kui Wang; Na Li; Jingwei Feng; Jing Wen; et al. (Science China Life Sciences, 2022)

Evolution of research topics on the Tibetan Plateau environment and ecology from 2000 to 2020: a paper mining - Keke Chang; Junyu Tao; Cheng Fang; Jian Li; Wenwu Zhou; Xutong Wang; Beibei Yan; Dan Zeng; Guanyi Chen (Environmental Science and Pollution Research, 2022)

Uncertainty and sensitivity analysis of spatial distributed roughness to a hydrodynamic water quality model: a case study on Lake Taihu, China - Yue Cheng; Yiping Li; Yaning Wang; Chunyan Tang; Yuanyuan Shi; Linda Sarpong; Ronghui Li; Kumud Acharya; Jinhua Li (Environmental Science and Pollution Research, 2022)

Lighting for work: a study on the effect of underground low-light environment on miners’ physiology - Jing Li; Yaru Qin; Cheng Guan; Yanli Xin; Zhen Wang; Ruikang Qi (Environmental Science and Pollution Research, 2022)

The combined toxicity of binary mixtures of antibiotics against the cyanobacterium Microcystis is dose-dependent: insight from a theoretical nonlinear combined toxicity assessment method - Yeyong Wang; Cheng Gao; Zhi Qu; Ming Li (Environmental Science and Pollution Research, 2022)

Effects of cryopreservation on the ultrastructure of coral larvae - Luca Cirino; Sujune Tsai; Li-Hsueh Wang; Wen-Chung Hsieh; Cheng-Liang Huang; Zhi-Hong Wen; Chiahsin Lin (Coral Reefs, 2022)

Tracing the Origins of Blueberries by Their Mineral Element Contents and 87Sr/86Sr Ratios - Qihang Li; Chaofeng Li; Shengyang Xiao; Heng Wang; Cheng Chen; Xiao Wei; Xuefeng Wen (Biological Trace Element Research, 2022)

Chemical constituents from the fruits of Piper longum L. and their vascular relaxation effect on rat mesenteric arteries - Dan Li; Rui Wang; Xiaohan Cheng; Jianfeng Yang; Yihui Yang; Huichong Qu; Sen Li; Shan Lin; Donghua Wei; Yuhua Bai; Xiaodong Zheng (Natural Product Research, 2022)

Influence of Functional Group Modification on the Toxicity of Nanoplastics - Haihong Zhang; Haodong Cheng; Yudi Wang; Zhenghua Duan; Wenjie Cui; Yansong Shi; Li Qin (Frontiers in Marine Science, 2022)
Nanoplastics (NPs) are ubiquitous in harvested organisms at various trophic levels, and more concerns on their diverse responses and wide species-dependent sensitivity are continuously increasing. However, systematic study on the toxic effects of NPs with different functional group modifications is still limited. In this review, we gathered and analyzed the toxic effects of NPs with different functional groups on microorganisms, plants, animals, and mammalian/human cells in vitro. The corresponding toxic mechanisms were also described. In general, most up-to-date relevant studies focus on amino (−NH 2 ) or carboxyl (−COOH)-modified polystyrene (PS) NPs, while research on other materials and functional groups is lacking. Positively charged PS-NH 2 NPs induced stronger toxicity than negatively charged PS-COOH. Plausible toxicity mechanisms mainly include membrane interaction and disruption, reactive oxygen species generation, and protein corona and eco-corona formations, and they were influenced by surface charges of NPs. The effects of NPs in the long-term exposure and in the real environment world also warrant further study.

Identification of A-to-I RNA editing profiles and their clinical relevance in lung adenocarcinoma - Cheng Wang; Mingtao Huang; Congcong Chen; Yuancheng Li; Na Qin; Zijian Ma; Jingyi Fan; Linnan Gong; Hui Zeng; Liu Yang; Xianfeng Xu; Jun Zhou; et al. (Science China Life Sciences, 2022)

Genome-wide identification and expression analysis of GL2-interacting-repressor (GIR) genes during cotton fiber and fuzz development - Xiaoxu Feng; Hailiang Cheng; Dongyun Zuo; Youping Zhang; Qiaolian Wang; Limin Lv; Shuyan Li; John Z. Yu; Guoli Song (Planta, 2022)

Effects of environmental factors on plant functional traits across different plant life forms in a temperate forest ecosystem - Xiaoqin Cheng; Tain Ping; Zuzheng Li; Tian Wang; Hairong Han; Howard E. Epstein (New Forests, 2022)

Flood vulnerability assessment using the triangular fuzzy number-based analytic hierarchy process and support vector machine model for the Belt and Road region - Yu Duan; Junnan Xiong; Weiming Cheng; Nan Wang; Yi Li; Yufeng He; Jun Liu; Wen He; Gang Yang (Natural Hazards, 2022)

The genomic history of southwestern Chinese populations demonstrated massive population migration and admixture among proto-Hmong–Mien speakers and incoming migrants - Yicheng Wang; Xing Zou; Mengge Wang; Didi Yuan; Li Yang; Yujie Zeng; Fang Cheng; Renkuan Tang; Guanglin He (Molecular Genetics and Genomics, 2022)

Enhanced transport and chromium remediation of nano-zero valent iron modified by tea polyphenol extracts and carboxymethyl cellulose in water–soil media - Xuyi Cheng; Shiqi Wang; Nan Xu; Li Yang; Pengcheng Jing; Jianping Chen (Journal of Soils and Sediments, 2022)

Correction to: Optimal coupling combinations between dripper discharge and irrigation interval of maize for seed production under plastic film-mulched drip irrigation in an arid region - Shimeng Ma; Ling Tong; Shaozhong Kang; Sufen Wang; Xuanyi Wu; Xiaona Cheng; Qiangqiang Li (Irrigation Science, 2022)

Effects of B-azolemiteacrylic on life-history traits and demographic parameters of two-spotted spider mite, Tetranychus urticae (Acari: Tetranychidae) - Suqin Shang; Yun Chang; Wei-Zhen Li; Wang Chang-Qing; Nie Peng-Cheng (Experimental and Applied Acarology, 2022)
The present study was conducted to evaluate sublethal effects of B-azolemiteacrylic on the two-spotted spider mite, Tetranychus urticae Koch (Acari: Tetranychidae). Female adults of T. urticae were exposed to LC 10 and LC 30 of the acaricide, and the effects on treated females and their offspring were evaluated. The results showed that the fecundity of F 0 female adults treated with LC 10 and LC 30 of B-azolemiteacrylic was reduced by 30.9 and 39.2%, respectively. Longevity and oviposition period of the females were significantly reduced as well. The developmental duration of egg and deutonymph stage of the F 1 generation were not significantly different from that of the control. The protonymph stage after LC 30 treatment lasted significantly longer, whereas the larva, deutonymph and female stage were significantly shorter than the control. The oviposition period of the F 1 generation was significantly shortened, the fecundity of each female decreased significantly, and the ratio of female-to-male was reduced too. Moreover, the average generation period of T. urticae after LC 10 and LC 30 treatments was shorter than that of the control, and the net production rate ( R 0 ), intrinsic rate of increase ( r m ) and finite rate of increase ( λ ) were all reduced by 33.3, 7.5 and 1.9% (LC 10 treatment) and by 51.3, 14.8 and 3.6% (LC 30 treatment), respectively. The population doubling time was prolonged by 7.5 and 14.8% after LC 10 and LC 30 treatments, respectively, compared with the control. These results indicate that B-azolemiteacrylic may effectively inhibit the development rate of the F 0 and F 1 populations of T. urticae , which will help design integrated strategies for the comprehensive control of T. urticae and rational use of pesticides in the field.

Promotional effect of ZrO2 and WO3 on bimetallic Pt-Pd diesel oxidation catalyst - Rongrong Fan; Zhaoqiang Li; Yu Wang; Yan Wang; Zhiyong Ding; Cheng Zhang; Na Kang; Xin Guo; Rong Wang (Environmental Science and Pollution Research, 2022)

Association of hearing loss with total and cause-specific mortality in US adults - Xiaobing Feng; Wenzhen Li; Man Cheng; Weihong Qiu; Ruyi Liang; Minjing Li; Weihong Chen; Dongming Wang (Environmental Science and Pollution Research, 2022)

Association between serum folate levels and blood concentrations of cadmium and lead in US adults - Zuxiang Wu; Huan Hu; Chenxi Wang; Ji Wu; Yurong Xiong; Yang Fu; Xiaoshu Cheng; Hai Su; Ping Li (Environmental Science and Pollution Research, 2022)

Dietary Calcium Alleviates Fluorine-Induced Liver Injury in Rats by Mitochondrial Apoptosis Pathway - Haojie Li; Zijun Hao; Li Wang; Jiarong Yang; Yangfei Zhao; Xiaofang Cheng; Haiyan Yuan; Jinming Wang (Biological Trace Element Research, 2022)

Using computational fluid dynamic simulation with Flow-3D to reveal the origin of the mushroom stone in the Xiqiao Mountain of Guangdong, China - Jian-cheng Li; Wei Wang; Yan-ming Zheng; Xiao-hao Wen; Jing Feng; Li Sheng; Chen Wang; Ming-kun Qiu (Journal of Mountain Science, 2022)

Identification of bacterial blight resistance genes in rice landraces from Yunnan Province, China - Caimei Zhao; Fuyou Yin; Ling Chen; Dingqin Li; Suqin Xiao; Qiaofang Zhong; Bo Wang; Xue Ke; Jian Fu; Xiang Li; Yue Chen; Lingxian Wang; et al. (Australasian Plant Pathology, 2022)
Bacterial blight (BB), a serious bacterial disease caused by pathogen Xanthomonas oryzae pv. oryzae ( Xoo ) affects rice growth and yield. Yunnan Province is regarded as a center of rice diversity in China and indeed the world, and has abundant rice landrace resources, which may offer prospective candidate donors in rice improvement and breeding. In this study, a set of 200 rice landraces were evaluated to determine their resistance to 10 pathogenic Xoo strains resistance by the leaf-clipping method. The results indicated that the tested rice landraces had different resistance levels against different Xoo strains. Multiple comparisons showed that the Xoo strain PXO99 was virulent to the tested rice landraces. Sixty-six rice landraces conferred resistance against at least one Xoo strain. These resistant rice landraces screened were then performed the presence of 14 cloned BB resistance genes by closely linked molecular markers and designed specific primers. The results showed that none of these resistant accessions contained xa13 , Xa21 , Xa27 , and Xa45(t) homologous fragments, while 9, 24, 4, 7, 9, 15, 1, 5, 4 and 27 accessions contained Xa1 , Xa2/Xa31(t) , Xa14 , Xa3/Xa26 , Xa4 , xa5 , Xa7 , Xa10 , Xa23 and xa25 homologous fragments, respectively. Sequence analysis further revealed that nucleotide variations around functional nucleotide polymorphisms region were observed within these accessions containing the Xa1 , Xa2/Xa31(t) , Xa14 , Xa3/Xa26 , Xa4 , xa5 , Xa10 , Xa23 and xa25 homologous fragments. These results along with phenotypic resistance spectrum supported that these accessions carried nine resistance homologous genes. Only one accession (Qishanggu_Wenshan) carried the Xa7 resistance gene. We also found that some resistant rice landraces, especially Xilandigu_Baoshan, and Laoyaling_Lincang without the above resistance genes, which mediated broad spectrum resistance to multiple Xoo strains, were identified as potential sources for breeding rice lines resistance to BB.

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

DAGDU: center location of tropical cyclones using Deviation Angle Gradient Distribution Uniformity from infrared satellite images - Chang-Jiang Zhang; Xiao-Jie Wang; Li-Cheng Xue (International Journal of Remote Sensing, 2021)

A Review of Methods for Ship Detection with Electro-Optical Images in Marine Environments - Liqian Wang; Shuzhen Fan; Yunxia Liu; Yongfu Li; Cheng Fei; Junliang Liu; Bohan Liu; Yakui Dong; Zhaojun Liu; Xian Zhao (Journal of Marine Science and Engineering, 2021)
The ocean connects all continents and is an important space for human activities. Ship detection with electro-optical images has shown great potential due to the abundant imaging spectrum and, hence, strongly supports human activities in the ocean. A suitable imaging spectrum can obtain effective images in complex marine environments, which is the premise of ship detection. This paper provides an overview of ship detection methods with electro-optical images in marine environments. Ship detection methods with sea–sky backgrounds include traditional and deep learning methods. Traditional ship detection methods comprise the following steps: preprocessing, sea–sky line (SSL) detection, region of interest (ROI) extraction, and identification. The use of deep learning is promising in ship detection; however, it requires a large amount of labeled data to build a robust model, and its targeted optimization for ship detection in marine environments is not sufficient.

Impacts of pavement on the growth and biomass of young pine, ash and maple trees - Bowen Cui; Xuming Wang; Yuebo Su; Yuanyuan Chen; Weiwei Yu; Cheng Gong; Li Li; Abdur Rehim; Xiaoke Wang (Trees, 2021)

Clinical Value of 3D-Printed Navigation Technology Combined with Neuroendoscopy for Intracerebral Hemorrhage - Yuqian Li; Hongyu Cheng; Zhenzhu Li; Haikang Zhao; Jiancai Wang; Peng Wang; Tongxin Jin; Guiyong Zheng; Haoxiang Ye; Shaopeng Li; Jun Zhang (Translational Stroke Research, 2021)

Longitudinal virological changes and underlying pathogenesis in hospitalized COVID-19 patients in Guangzhou, China - Zhengtu Li; Yinhu Li; Ruilin Sun; Shaoqiang Li; Lingdan Chen; Yangqing Zhan; Mingzhou Xie; Jiasheng Yang; Yanqun Wang; Airu Zhu; Guoping Gu; Le Yu; et al. (Science China Life Sciences, 2021)

Effective Thermal Conductivity Estimation of Fractured Rock Masses - Zheng-Wei Li; Yuan Liu; Shi-Ming Mei; Shi-Cheng Xing; Xiao-Kai Wang (Rock Mechanics and Rock Engineering, 2021)

Deformation structure and exhumation process of the Laojunshan gneiss dome in southeastern Yunnan of China - Zhong Liu; Shuyun Cao; Yanlong Dong; Wei Li; Xuemei Cheng; Haobo Wang; Meixia Lyu (Science China Earth Sciences, 2021)

Correction to: μ-Opioid Receptor–Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation - Hui Gao; Yuxin Zhang; Yansong Li; Haiqing Chang; Bo Cheng; Na Li; Wei Yuan; Shuang Li; Qiang Wang (Molecular Neurobiology, 2021)

c-Abl Tyrosine Kinase-Mediated Neuronal Apoptosis in Subarachnoid Hemorrhage by Modulating the LRP-1-Dependent Akt/GSK3β Survival Pathway - Cong Yan; Hongwei Yu; Yao Liu; Pei Wu; Chunlei Wang; Hongbo Zhao; Kongbin Yang; Qi Shao; Yingqiang Zhong; Wenyang Zhao; Jingwei Li; Nan Liu; et al. (Journal of Molecular Neuroscience, 2021)

Occurrence, source apportionment, and carcinogenic risk assessment of polycyclic aromatic hydrocarbons in urban road dusts in Shanghai - Xue-Tong Wang; Rui Fu; Ying Zhou; Cheng-Lin Wang; Guo-Fa Ren; Xiao-Li Wang; Hui Li (Environmental Science and Pollution Research, 2021)

Seasonal fluctuation of aerosolization ratio of bioaerosols and quantitative microbial risk assessment in a wastewater treatment plant - Rui-ning Wang; Xiang Li; Cheng Yan (Environmental Science and Pollution Research, 2021)

Integrated landscape approaches to building resilience and multifunctionality in the Kailash Sacred Landscape, China - Pei-li Shi; Cheng Duan; Li Wang; Ning Wu; Rajan Kotru; Janita Gurung (Journal of Mountain Science, 2021)

Discriminating hydrocarbon generation potential of coaly source rocks and their contribution: a case study from the Upper Paleozoic of Bohai Bay Basin, China - Jinjun Xu; Da Lou; Qiang Jin; Lixin Fu; Fuqi Cheng; Shuhui Zhou; Xiuhong Wang; Chao Liang; Fulai Li (Frontiers of Earth Science, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

Cytotoxic triterpenoid glycosides from leaves of Cyclocarya paliurus - Hui-Hui Sun; Wen-Yan Lv; Jie Tan; Yu-Cheng Tang; Hui Zhu; Jian-Bo Qu; Jing Li; Jian-Ping Wu; Xi-Wen Chang; Zhi-Chun Yang; Wen-Xuan Wang; Zu-Hui Chen; et al. (Natural Product Research, 2021)

Effect of coronatine on synthesis of cephalotaxine in suspension cells of Cephalotaxus mannii and its transcriptome analysis - Liu-Yan Wang; Qiao Zhang; Zi-Qi Wang; Yong-Cheng Li (Plant Cell, Tissue and Organ Culture (PCTOC), 2021)

RETRACTED ARTICLE: Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine Sulfate - Chang Ren; Yao Wang; Mei Zhang; Dexuan Kong; Chen Ning; Yujie Cheng; Yueying Bian; Mengqi Sun; Shengdi Su; Yucong Wang; Yongjie Zhang; Yang Lu; et al. (Pharmaceutical Research, 2021)

TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain - Lu Wang; Han-Yu Yang; Cai-Xia Zang; Jun-Mei Shang; Hui Liu; Zi-Hong Zhang; Fang-Yu Yuan; Cheng Ju; Fang-Yuan Li; Xiu-Qi Bao; Dan Zhang (Molecular Neurobiology, 2021)

Response of Escherichia coli to hydrogen nanobubbles: an in vitro evaluation using synchrotron infrared spectroscopy - Jinfang Lu; Jin Zheng; Yadi Wang; Jie Cheng; Xueling Li; Jun Hu; Bin Li; Junhong Lü (Journal of Zhejiang University-SCIENCE B, 2021)

Ecological risk assessment of heavy metals in farmland soils in Beijing by three improved risk assessment methods - Rui Chen; Xuying Cai; Guoyu Ding; Fumin Ren; Qi Wang; Nuo Cheng; Jiaxing Liu; Lanxin Li; Rongguang Shi (Environmental Science and Pollution Research, 2021)

A comprehensive exploration on pollution characteristics and health risks of potentially toxic elements in indoor dust from a large Cu smelting area, Central China - Han-Zhi Wang; Li-Mei Cai; Shuo Wang; Guo-Cheng Hu; Lai-Guo Chen (Environmental Science and Pollution Research, 2021)

Implantation of Bone Marrow Mesenchymal Stem Cells into Small Intestinal Submucosa Improves Bile Duct Injury in Rabbits - Ying Li; Piao Wang; Xiao-dong Hu; Jing-da Zeng; Cheng Fang; Yu Gan; Fang-yi Peng; Xiao-li Yang; De Luo; Bo Li; Song Su (Tissue Engineering and Regenerative Medicine, 2021)

The change of hydrological variables and its effects on vegetation in Central Asia - Qing Peng; Ranghui Wang; Yelin Jiang; Cheng Li; Wenhui Guo (Theoretical and Applied Climatology, 2021)
Water is an important factor that affects local ecological environments, especially in drylands. The hydrological cycle and vegetation dynamics in Central Asia (CA) have been severely affected by climate change. In this study, we employed data from Gravity Recovery and Climate Experiment (GRACE), Global Land Data Assimilation System (GLDAS), Global Land Evaporation Amsterdam Model, and Climate Research Unit to analyze the spatiotemporal changes in hydrological factors (terrestrial water storage (TWS), evapotranspiration, precipitation, and groundwater) in CA from 2003 to 2015. Additionally, the spatiotemporal changes in vegetation dynamics and the influence of hydrological variables on vegetation were analyzed. The results showed that the declining rates of precipitation, evapotranspiration, GRACE-TWS change, GLDAS-TWS change and GW change were 0.40 mm/year, 0.11 mm/year, 50.46 mm/year ( p < 0.05), 8.38 mm/year, and 41.18 mm/year ( p < 0.05), respectively. Human activity (e.g., groundwater pumping) was the dominant in determining the GW decline in CA. Precipitation dominated the changes in evapotranspiration, GRACE-TWS and GLDAS-TWS ( p < 0.05). The 2- to 3-month lagging signal has to do with the transportation from the ground surface to groundwater. The change in the normalized difference vegetation index (NDVI) from 2003 to 2015 indicated the slight vegetation degradation in CA. The results highlighted that precipitation, terrestrial water storage, and soil moisture make important contributions to the vegetation dynamics changes in CA. The effect of precipitation on vegetation growth in spring was significant ( p < 0.05), while the soil moisture effect on vegetation in summer and autumn was higher than that of precipitation.

Human activity and climate change triggered the expansion of rocky desertification in the karst areas of Southwestern China - Chaojun Chen; Daoxian Yuan; Hai Cheng; Tsailuen Yu; Chuanchou Shen; R. Lawrence Edwards; Yao Wu; Siya Xiao; Jian Zhang; Tao Wang; Ran Huang; Ziqi Liu; et al. (Science China Earth Sciences, 2021)

Identification of RNA helicases in Medicago truncatula and their expression patterns under abiotic stress - Jie Cheng; Songsong Zhou; Kun Yang; Hongyang Yu; Rongrong Chen; Liming Zeng; Hua Li; Yihua Wang; Jianbo Song (Physiology and Molecular Biology of Plants, 2021)

SETD3 Downregulation Mediates PTEN Upregulation-Induced Ischemic Neuronal Death Through Suppression of Actin Polymerization and Mitochondrial Function - Xiangyu Xu; Yu Cui; Congqin Li; Yuyang Wang; Jing Cheng; Songfeng Chen; Jiangdong Sun; Jinyang Ren; Xujin Yao; Jingchen Gao; Xiaohong Huang; Qi Wan; et al. (Molecular Neurobiology, 2021)

Additive and Epistatic QTL on Cadmium (Cd) Tolerance Associated with Seed Germinating Ability in Rice - Changsheng Li; Peng Wang; Guangliang Wu; Yanning Wang; Qin Cheng; Yicong Cai; Dahu Zhou; Caijing Li; Xiangyu Zhang; Jingai Tan; Cuijuan Li; Haohua He; et al. (Journal of Plant Growth Regulation, 2021)

MiR-590-5p inhibits pathological hypertrophy mediated heart failure by targeting RTN4 - Ping Fan; Likun Zhang; Tianyu Cheng; Jing Wang; Junyun Zhou; Li Zhao; Cuie Hua; Quan Xia (Journal of Molecular Histology, 2021)

Examination of acephate absorption, transport, and accumulation in maize after root irrigation for Spodoptera frugiperda control - Jiyingzi Wu; Xianjia Li; Ruiquan Hou; Kunyu Zhao; Yongqing Wang; Suqing Huang; Dongmei Cheng; Zhixiang Zhang (Environmental Science and Pollution Research, 2021)

Large-scale atmospheric circulation influences the ice core d-excess record from the central Tibetan Plateau - Lili Shao; Lide Tian; Zhongyin Cai; Cheng Wang; Yao Li (Climate Dynamics, 2021)

Combining geophysical methods, drilling, and monitoring techniques to investigate carbonaceous shale landslides along a railway line: a case study on Jiheng Railway, China - Maoxin Su; Kai Cheng; Yimin Liu; Yiguo Xue; Peng Wang; Kai Zhang; Congcong Li (Bulletin of Engineering Geology and the Environment, 2021)

Development of a dual-labeled, hydrolysis probe-based, real-time quantitative PCR assay for detection of both genotypes of duck circovirus-1 (DuCV-1) and DuCV-2 - Lin Zhang; Wenming Jiang; Fuyou Zhang; Yang Li; Jinping Li; Shaobo Liang; Xiaohui Yu; Cheng Peng; Shuo Liu; Jingjing Wang; Shuhong Sun; Hualei Liu (Virus Genes, 2021)

Performance of rectangular closed diaphragm walls in gently sloping liquefiable deposits subjected to different earthquake ground motions - Jianlei Zhang; Qiangong Cheng; Yan Li; Yuheng Qiu; Yufeng Wang; Jiujiang Wu (Earthquake Engineering and Engineering Vibration, 2021)

24-epibrassinolide enhanced cold tolerance of winter turnip rape (Brassica rapa L.) - Yao Li; Yuanpei Sun; Cheng Ma; Xin Kang; Juan Wang; Tengguo Zhang (Biologia, 2021)

Evaluation of the antiviral activity of naringenin, a major constituent of Typha angustifolia , against white spot syndrome virus in crayfish Procambarus clarkii - Zhong‐Chen Sun; Cheng Chen; Fei‐Fan Xu; Bing‐Ke Li; Jing‐Lei Shen; Tao Wang; Hai‐Feng Jiang; Gao‐Xue Wang (Journal of Fish Diseases, 2021)
White spot syndrome virus (WSSV) is a serious pathogen threatening global crustacean aquaculture with no commercially available drugs. Herbal medicines widely used in antiviral research offer a rich reserve for drug discovery. Here, we investigated the inhibitory activity of 13 herbal medicines against WSSV in crayfish Procambarus clarkii and discovered that naringenin (NAR) has potent anti‐WSSV activity. In the preliminary screening, the extracts of Typha angustifolia displayed the highest inhibitory activity on WSSV replication (84.62%, 100 mg/kg). Further, NAR, the main active compound of T. angustifolia, showed a much higher inhibition rate (92.85%, 50 mg/kg). NAR repressed WSSV proliferation followed a dose‐dependent manner and significantly improved the survival of WSSV‐challenged crayfish. Moreover, pre‐ or post‐treatment of NAR displayed a comparable inhibition on the viral loads. NAR decreased the transcriptional levels of vital genes in viral life cycle, particularly for the immediately early‐stage gene ie1 . Further results showed that NAR could decrease the STAT gene expression to block ie1 transcription. Besides, NAR modulated immune‐related gene Hsp70 , antioxidant ( cMnSOD, mMnSOD, CAT, GST ), anti‐inflammatory ( COX‐1 , COX‐2 ) and pro‐apoptosis‐related factors (Bax and BI‐1) to inhibit WSSV replication. Overall, these results suggest that NAR may have the potential to be developed as preventive or therapeutic agent against WSSV.

Genotype and virulence gene analyses of Bacillus cereus group clinical isolates from the Chinese softshell turtle ( Pelodiscus sinensis ) in Taiwan - Li‐Wu Cheng; Shreesha Rao; Sayuj Poudyal; Pei‐Chi Wang; Shih‐Chu Chen (Journal of Fish Diseases, 2021)
Chinese softshell turtles ( Pelodiscus sinensis ) (CST) are susceptible to infections by bacteria belonging to the Bacillus cereus group (Bcg). Bcg includes several closely related species, two of which, B . cereus and B . thuringiensis , are pathogens of aquatic animals or insects. In the present study, we collected 57 Bcg isolates from diseased CST from 2016 to 2019 in Kaohsiung and Pingtung, where most CST farms are located in Taiwan. All isolates were divided into four genotypes with two restriction enzymes, Sma I and Not I, by pulsed‐field gel electrophoresis and enterobacterial repetitive intergenic consensus–polymerase chain reaction (ERIC‐PCR). Representative isolates from each genotype were subjected to phylogenetic tree analysis using 16S rDNA and pyruvate carboxylase genes as phylogenetic markers, and these CST isolates appeared in different clades. PCR was performed targeting six selected virulence genes, four of which were detected in CST isolates, including cytotoxin K (1/57), hblC of the haemolysin BL complex (46/57), nheA of the non‐haemolytic enterotoxin complex (52/57) and enterotoxin FM (57/57), whereas cereulide synthetase and cereulide peptide synthase‐like genes were not detected in any isolates.

A semi-supervised learning method for hyperspectral imagery based on self-training and local-based affinity propagation - Haimiao Ge; Haizhu Pan; Liguo Wang; Cheng Li; Yanzhong Liu; Wenlong Zhu; Yanping Teng (International Journal of Remote Sensing, 2021)

Genetic control of Fusarium head blight resistance in two Yangmai 158-derived recombinant inbred line populations - Haisheng Yan; Guoqiang Li; Jinxing Shi; ShunShun Tian; Xiaoqiu Zhang; Rui Cheng; Xin Wang; Yang Yuan; Shouyang Cao; Jiyang Zhou; Zhongxin Kong; Haiyan Jia; et al. (Theoretical and Applied Genetics, 2021)

Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica) - Hui Zhi; Qiang He; Sha Tang; Junjun Yang; Wei Zhang; Huifang Liu; Yanchao Jia; Guanqing Jia; Aiying Zhang; Yuhui Li; Erhu Guo; Ming Gao; et al. (Theoretical and Applied Genetics, 2021)

Co-editing PINK1 and DJ-1 Genes Via Adeno-Associated Virus-Delivered CRISPR/Cas9 System in Adult Monkey Brain Elicits Classical Parkinsonian Phenotype - Hao Li; Shihao Wu; Xia Ma; Xiao Li; Tianlin Cheng; Zhifang Chen; Jing Wu; Longbao Lv; Ling Li; Liqi Xu; Wenchao Wang; Yingzhou Hu; et al. (Neuroscience Bulletin, 2021)
Whether direct manipulation of Parkinson’s disease (PD) risk genes in the adult monkey brain can elicit a Parkinsonian phenotype remains an unsolved issue. Here, we used an adeno-associated virus serotype 9 (AAV9)-delivered CRISPR/Cas9 system to directly co-edit PINK1 and DJ-1 genes in the substantia nigras (SNs) of two monkey groups: an old group and a middle-aged group. After the operation, the old group exhibited all the classic PD symptoms, including bradykinesia, tremor, and postural instability, accompanied by key pathological hallmarks of PD, such as severe nigral dopaminergic neuron loss (>64%) and evident α-synuclein pathology in the gene-edited SN. In contrast, the phenotype of their middle-aged counterparts, which also showed clear PD symptoms and pathological hallmarks, were less severe. In addition to the higher final total PD scores and more severe pathological changes, the old group were also more susceptible to gene editing by showing a faster process of PD progression. These results suggested that both genetic and aging factors played important roles in the development of PD in the monkeys. Taken together, this system can effectively develop a large number of genetically-edited PD monkeys in a short time (6–10 months), and thus provides a practical transgenic monkey model for future PD studies.

Residual Recurrence Risk of Ischemic Cerebrovascular Events: Elements and Implications - Jiejie Li; Zixiao Li; Tian-jie Lyu; Si Cheng; Yuehua Pu; Yongjun Wang (Neuroscience Bulletin, 2021)

Particulate matter pollution and emergency room visits for respiratory diseases in a valley Basin city of Northwest China - Bowen Cheng; Yuxia Ma; Hang Wang; Jiahui Shen; Yifan Zhang; Lingyun Guo; Yongtao Guo; Mingji Li (Environmental Geochemistry and Health, 2021)

Human Methylmercury Exposure and Potential Impacts in Central Tibet: Food and Traditional Tibetan Medicine - Menghan Cheng; Maodian Liu; Dou Li; Qing Luo; Zhihao Zhang; Liuliang Yuan; Chenghao Yu; Han Xie; Huiming Lin; Qianru Zhang; De Ji; Xuejun Wang (Bulletin of Environmental Contamination and Toxicology, 2021)

Identification of a 193 bp promoter region of TaNRX1-D gene from common wheat that contributes to osmotic or ABA stress inducibility in transgenic Arabidopsis - Jie Cheng; Fan Wei; Mingfei Zhang; Nan Li; Tianqi Song; Yong Wang; Dongsheng Chen; Jishan Xiang; Xiaoke Zhang (Genes & Genomics, 2021)

Detrimental impact of hypoxia on the mortality, growth, reproduction, and enzyme activities of planktonic mysid Neomysis awatschensis - Qiao-ning Wang; Xiao-dong Li; Tian Yan; Jing-jing Song; Ren-cheng Yu; Ming-jiang Zhou (Aquatic Ecology, 2021)

Modulation of the 5-HT 3 A receptor current by desacylbaldrinal - Li-Xia Wang; Hu-Lan Chen; Hong-Ling Yan; Fei Tang; Hai Zhang; Hong-Xiang Li; Qiang Ye; Cheng Peng; Yu-Zhu Tan (Natural Product Research, 2021)

Proteomics provides individualized options of precision medicine for patients with gastric cancer - Wenwen Huang; Dongdong Zhan; Yazhuo Li; Nairen Zheng; Xin Wei; Bin Bai; Kecheng Zhang; Mingwei Liu; Xuefei Zhao; Xiaotian Ni; Xia Xia; Jinwen Shi; et al. (Science China Life Sciences, 2021)

Identification and function analysis of fasciclin-like arabinogalactan protein family genes in pear (Pyrus bretschneideri) - Xiaoqiang Li; Mengyu Cheng; Chao Tang; Xiaoxuan Zhu; Kaijie Qi; Shaoling Zhang; Juyou Wu; Peng Wang (Plant Systematics and Evolution, 2021)

Remelting of a Neoproterozoic arc root: origin of the Pulang and Songnuo porphyry Cu deposits, Southwest China - Dian-Zhong Wang; Ruizhong Hu; Pete Hollings; Xian-Wu Bi; Hong Zhong; Li-Chuan Pan; Cheng-Biao Leng; Ming-Liang Huang; Jing-Jing Zhu (Mineralium Deposita, 2021)

The prograde-to-retrograde evolution of the Huangshaping skarn deposit (Nanling Range, South China) - Da-Peng Zhu; Huan Li; Thomas J. Algeo; Wei-Cheng Jiang; Chong Wang (Mineralium Deposita, 2021)

Multi-indices analysis of heavy precipitation changes in Anhui Province, China - Cheng Li; Jinhua Chen; Ranghui Wang; Jin Huang; Zhonghua Qian; Yang Xu (Meteorology and Atmospheric Physics, 2021)

A small attentional YOLO model for landslide detection from satellite remote sensing images - Libo Cheng; Jia Li; Ping Duan; Mingguo Wang (Landslides, 2021)

Patient Confidential Information Transmission Using the Integration of PSO-Based Biomedical Signal Steganography and Threshold-Based Compression - Shih-Ying Chen; Shan-Ju Lin; Ming-Cheng Tsai; Ming-Dar Tsai; Yih-Jing Tang; Shuo-Tsung Chen; Li-Hsiang Wang (Journal of Medical and Biological Engineering, 2021)

Characterization of AV422 from Haemaphysalis flava ticks in vitro - Lei Liu; Hao Tang; De-yong Duan; Jin-bao Liu; Jie Wang; Li-li Feng; Tian-yin Cheng (Experimental and Applied Acarology, 2021)

Noise reduction method of microseismic signal of water inrush in tunnel based on variational mode method - Liping Li; Hao Jin; Yanhao Chen; Shuai Cheng; Huijiang Hu; Sheng Wang (Bulletin of Engineering Geology and the Environment, 2021)

Transcriptome analysis reveals hub genes in the hepatopancreas of Exopalaemon carinicauda in response to hypoxia and reoxygenation - Wenjun Shi; Pan Wang; Runhao Hu; Xihe Wan; Hui Shen; Hui Li; Libao Wang; Yi Qiao; Ge Jiang; Jie Cheng; Zeyu Yang (Aquaculture International, 2021)

RSF1 requires CEBP/β and hSNF2H to promote IL-1β-mediated angiogenesis: the clinical and therapeutic relevance of RSF1 overexpression and amplification in myxofibrosarcomas - Chien-Feng Li; Ti-Chen Chan; Cheng-I. Wang; Fu-Min Fang; Po-Chun Lin; Shih-Chen Yu; Hsuan-Ying Huang (Angiogenesis, 2021)

The developmental regulator PatD modulates assembly of the cell‐division protein FtsZ in the cyanobacterium Anabaena sp. PCC 7120 - Li Wang; Tian‐Cai Niu; Ana Valladares; Gui‐Ming Lin; Ju‐Yuan Zhang; Antonia Herrero; Wen‐Li Chen; Cheng‐Cai Zhang (Environmental Microbiology, 2021)
Summary FtsZ is a tubulin‐like GTPase that polymerizes to initiate the process of cell division in bacteria. Heterocysts are terminally differentiated cells of filamentous cyanobacteria that have lost the capacity for cell division and in which the ftsZ gene is downregulated. However, mechanisms of FtsZ regulation during heterocyst differentiation have been scarcely investigated. The patD gene is NtcA dependent and involved in the optimization of heterocyst frequency in Anabaena sp. PCC 7120. Here, we report that the inactivation of patD caused the formation of multiple FtsZ‐rings in vegetative cells, cell enlargement, and the retention of peptidoglycan synthesis activity in heterocysts, whereas its ectopic expression resulted in aberrant FtsZ polymerization and cell division. PatD interacted with FtsZ, increased FtsZ precipitation in sedimentation assays, and promoted the formation of thick straight FtsZ bundles that differ from the toroidal aggregates formed by FtsZ alone. These results suggest that in the differentiating heterocysts, PatD interferes with the assembly of FtsZ. We propose that in Anabaena FtsZ is a bifunctional protein involved in both vegetative cell division and regulation of heterocyst differentiation. In the differentiating cells PatD‐FtsZ interactions appear to set an FtsZ activity that is insufficient for cell division but optimal to foster differentiation.

Short-term waterlogging-induced autophagy in root cells of wheat can inhibit programmed cell death - Li-Lang Zhou; Kai-Yue Gao; Li-Sha Cheng; Yue-Li Wang; Yi-Keng Cheng; Qiu-Tao Xu; Xiang-Yi Deng; Ji-Wei Li; Fang-Zhu Mei; Zhu-Qing Zhou (Protoplasma, 2021)

Citrus NIP5;1 aquaporin regulates cell membrane water permeability and alters PIPs plasma membrane localization - Mingfei Zhang; Ruilian Liu; Hai Liu; Hongbin Yang; Xin Li; Ping Wang; Feng Zhu; Rangwei Xu; Shaowu Xue; Yunjiang Cheng (Plant Molecular Biology, 2021)

Transcriptome analysis of differentially expressed genes in chrysanthemum MET1 RNA interference lines - Dong-ru Kang; Yi Zhu; Shuai-lei Li; Peng-hui Ai; Muhammad Ayoub Khan; Hong-xu Ding; Ying Wang; Zi-cheng Wang (Physiology and Molecular Biology of Plants, 2021)

Restricted Feeding Resets Endogenous Circadian Rhythm in Female Mice Under Constant Darkness - Yue Mei; Huajing Teng; Zhigang Li; Cheng Zeng; Yuanyuan Li; Wei Song; Kaifan Zhang; Zhong Sheng Sun; Yan Wang (Neuroscience Bulletin, 2021)

μ-Opioid Receptor–Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation - Hui Gao; Yuxin Zhang; Yansong Li; Haiqing Chang; Bo Cheng; Na Li; Wei Yuan; Shuang Li; Qiang Wang (Molecular Neurobiology, 2021)

The influence of VDR polymorphisms on the type 2 diabetes susceptibility in Chinese: an interaction with hypertriglyceridemia - Dongdong Zhang; Cheng Cheng; Yan Wang; Yuan Xue; Yaping Liu; Yiming Liu; Mingming Feng; Ze Xu; Wenjie Li; Xing Li (Molecular Genetics and Genomics, 2021)

Identification of potential sex-related genes in Siniperca chuatsi - Qiaoying Zhu; Chong Han; Cheng Peng; Xingni Zhou; Chongwei Wang; Linqiang Han; Shuisheng Li; Guifeng Li; Haoran Lin; Yong Zhang (Journal of Oceanology and Limnology, 2021)

Phosphorus fertilization rather than nitrogen fertilization, growing season and plant successional stage structures arbuscular mycorrhizal fungal community in a subtropical forest - Pulak Maitra; Yong Zheng; Yong-Long Wang; Dipa Mandal; Peng-Peng Lü; Cheng Gao; Busayo Joshua Babalola; Niu-Niu Ji; Xing-Chun Li; Liang-Dong Guo (Biology and Fertility of Soils, 2021)

Exploring the validity of using immersive virtual reality technique on perceived crowding of recreational environment - Ting-Hsuan Wang; Wan-Hsuan Wu; Li Shen; Chia-Kuen Cheng (Landscape and Ecological Engineering, 2021)

Foetidibacter luteolus gen. nov., sp. nov., isolated from the rhizosphere of Salvia miltiorrhiza - Qian Pu; Guo-hong Zeng; Gui-wei Wang; Ling-er Lu; Ang Li; Xu-rui Cheng; Xue-ying Wang; Ou Li; Cong Sun; Xiu-fang Hu (Archives of Microbiology, 2021)

Glaciibacter flavus sp. nov., isolated from a lichen sample - De-Feng An; Long-Qian Jiang; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Ming-Guo Jiang; Lei Lang; Li-Song Wang; Johannes F. Imhoff; Cheng-Lin Jiang; Yi Jiang (Archives of Microbiology, 2021)

Heavy Metal Adsorption and Release on Polystyrene Particles at Various Salinities - Beta Susanto Barus; Kai Chen; Minggang Cai; Rongmao Li; Huorong Chen; Cong Li; Jun Wang; Sha-Yen Cheng (Frontiers in Marine Science, 2021)
Microplastics (MPs) and heavy metals are two major types of pollutants that interact with each other, but they are poorly understood. Polystyrene (PS) is one type of MPs that is often detected in aquatic environments. In this study, we examined the adsorption capacity and release rate of heavy metals with respect to different particle sizes of PS, heavy metals, initial heavy metal concentrations, and salinities. Virgin (new) PS with diameters of 20, 50, 130, and 250 μm was used in this study, and four heavy metals (lead, cadmium, copper, and zinc) were used. The results showed that larger PS particle sizes adsorbed more heavy metals even though it took longer to achieve equilibrium adsorption. An increase in heavy metal concentration caused the adsorption capacity (μg g –1 ) of PS particles to also increase, but the adsorption rate (%) decreased. Increased salinity of the heavy metal solution resulted in a slower adsorption time and a lower adsorption capacity and release rate from the surface of PS particles. Different heavy metals also had different adsorption capacities. Pb was consistently more highly adsorbed by MPs, followed by Cu, Zn, and Cd. Larger PS sizes released heavy metals faster than smaller PS sizes, and the amounts of heavy metals released were higher. The heavy metal with the highest release rate was Cd, followed by Pb, Cu, and Zn. Finally, our findings highlight the interactions between PS and heavy metals and strongly support that PS particles can act as vectors for heavy metals in aquatic systems.

Identification of differentially expressed genes associated with aluminum resistance in the soybean plant - Jing-xuan Wang; Bo Wang; Lu-bin Cui; Hao Xie; Run-zhi Li; Cheng Wang; Zhang-jie Nan; Yu-shu Liu; Jing-yu Ma; Yun-jin Sun; Wei-yu Li (Physiology and Molecular Biology of Plants, 2021)

The Role of lncRNA TUG1 in the Parkinson Disease and Its Effect on Microglial Inflammatory Response - Jiang Cheng; Yangyang Duan; Fengting Zhang; Jin Shi; Hui Li; Feng Wang; Haining Li (NeuroMolecular Medicine, 2021)

Galectin-9 Promotes Neuronal Restoration via Binding TLR-4 in a Rat Intracerebral Hemorrhage Model - Tianyu Liang; Cheng Ma; Tianyi Wang; Ruming Deng; Jiasheng Ding; Wenjie Wang; Zhongmou Xu; Xiang Li; Haiying Li; Qing Sun; Haitao Shen; Zhong Wang; et al. (NeuroMolecular Medicine, 2021)

Syntheses and anticancer activities of novel glucosylated (−)-epigallocatechin-3-gallate derivatives linked via triazole rings - Bo-Ya Shi; Ze-Hao Wang; Ning Zhang; Yin-Rong Xie; Xiu-Li Sun; Hao-Nan Yang; Yi-Long Wu; Cheng-Ting Zi; Xuan-Jun Wang; Jun Sheng (Medicinal Chemistry Research, 2021)